Homo sapiens

38 known processes

MMS22L

MMS22-like, DNA repair protein

(Aliases: C6orf167,DKFZp686C20164,DKFZp781C2113,FLJ46180,dJ39B17.2,KIAA1900)

MMS22L biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication GO:0006260 116 0.992
replication fork processing GO:0031297 13 0.992
dna dependent dna replication GO:0006261 44 0.976
protein polyubiquitination GO:0000209 110 0.959
double strand break repair via homologous recombination GO:0000724 50 0.951
protein modification by small protein conjugation GO:0032446 342 0.917
double strand break repair GO:0006302 101 0.910
recombinational repair GO:0000725 50 0.846
protein ubiquitination GO:0016567 314 0.802
cellular response to dna damage stimulus GO:0006974 379 0.653
positive regulation of programmed cell death GO:0043068 249 0.597
nucleosome assembly GO:0006334 50 0.592
protein dna complex assembly GO:0065004 64 0.561
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.559
chromatin assembly GO:0031497 61 0.547
post embryonic development GO:0009791 2 0.481
dna replication independent nucleosome organization GO:0034724 27 0.474
skeletal system morphogenesis GO:0048705 24 0.461
dna conformation change GO:0071103 113 0.446
cellular ketone metabolic process GO:0042180 80 0.439
odontogenesis GO:0042476 25 0.422
dna repair GO:0006281 198 0.402
amine metabolic process GO:0009308 44 0.390
positive regulation of apoptotic process GO:0043065 246 0.384
negative regulation of apoptotic process GO:0043066 316 0.366
positive regulation of cell death GO:0010942 263 0.365
regulation of intracellular protein transport GO:0033157 123 0.293
negative regulation of programmed cell death GO:0043069 321 0.283
cellular amine metabolic process GO:0044106 41 0.267
dna replication initiation GO:0006270 6 0.253
nuclear export GO:0051168 69 0.249
regulation of cellular amino acid metabolic process GO:0006521 6 0.243
regulation of protein localization GO:0032880 296 0.243
neutral lipid biosynthetic process GO:0046460 11 0.243
negative regulation of intracellular protein transport GO:0090317 42 0.237
negative regulation of transport GO:0051051 176 0.228
organ morphogenesis GO:0009887 147 0.220
regulation of cellular ketone metabolic process GO:0010565 50 0.219
protein export from nucleus GO:0006611 29 0.218
negative regulation of cell death GO:0060548 345 0.217
regulation of dna replication GO:0006275 68 0.214
odontogenesis of dentin containing tooth GO:0042475 10 0.212
cellular amino acid metabolic process GO:0006520 116 0.182
chromatin disassembly GO:0031498 13 0.181
mitotic cell cycle phase transition GO:0044772 162 0.180
skeletal system development GO:0001501 79 0.176
cellular macromolecular complex assembly GO:0034622 324 0.174
regulation of protein transport GO:0051223 213 0.173
positive regulation of cellular amine metabolic process GO:0033240 7 0.160
regulation of cellular amine metabolic process GO:0033238 11 0.160
nuclear transport GO:0051169 179 0.157
negative regulation of cytoplasmic transport GO:1903650 46 0.149
intracellular protein transport GO:0006886 270 0.142
regulation of nucleocytoplasmic transport GO:0046822 98 0.131
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.112
regulation of establishment of protein localization GO:0070201 242 0.108
cytoplasmic transport GO:0016482 379 0.108
chromosome segregation GO:0007059 114 0.107
nucleocytoplasmic transport GO:0006913 176 0.102
regulation of intracellular transport GO:0032386 195 0.100
negative regulation of dna replication GO:0008156 29 0.094
histone acetylation GO:0016573 93 0.094
female gamete generation GO:0007292 2 0.089
regulation of protein export from nucleus GO:0046825 15 0.088
protein acylation GO:0043543 138 0.086
response to inorganic substance GO:0010035 127 0.084
negative regulation of notch signaling pathway GO:0045746 10 0.082
histone modification GO:0016570 251 0.081
peptidyl tyrosine phosphorylation GO:0018108 170 0.079
acylglycerol metabolic process GO:0006639 27 0.073
cell morphogenesis GO:0000902 296 0.072
regulation of gene expression epigenetic GO:0040029 73 0.072
regulation of protein kinase activity GO:0045859 289 0.072
dna replication dependent nucleosome organization GO:0034723 32 0.068
regulation of transferase activity GO:0051338 355 0.067
regulation of apoptotic signaling pathway GO:2001233 175 0.066
regulation of proteasomal protein catabolic process GO:0061136 87 0.066
purine containing compound catabolic process GO:0072523 411 0.066
multicellular organismal aging GO:0010259 3 0.065
protein catabolic process GO:0030163 325 0.064
regulation of cytoplasmic transport GO:1903649 149 0.064
peptidyl lysine modification GO:0018205 144 0.062
head development GO:0060322 108 0.062
glycerolipid biosynthetic process GO:0045017 51 0.061
positive regulation of cellular component organization GO:0051130 376 0.061
regulation of protein catabolic process GO:0042176 155 0.058
nucleoside triphosphate metabolic process GO:0009141 422 0.054
regulation of anatomical structure morphogenesis GO:0022603 286 0.053
lipid metabolic process GO:0006629 381 0.052
mrna splicing via spliceosome GO:0000398 89 0.051
cellular response to abiotic stimulus GO:0071214 117 0.051
response to uv GO:0009411 73 0.049
regulation of dna metabolic process GO:0051052 153 0.049
determination of adult lifespan GO:0008340 2 0.049
negative regulation of dna metabolic process GO:0051053 57 0.048
positive regulation of protein kinase activity GO:0045860 190 0.048
peptidyl lysine acetylation GO:0018394 101 0.047
cell projection organization GO:0030030 252 0.047
organelle fission GO:0048285 149 0.047
chromatin organization GO:0006325 351 0.046
oogenesis GO:0048477 2 0.046
regulation of kinase activity GO:0043549 314 0.044
positive regulation of apoptotic signaling pathway GO:2001235 70 0.044
negative regulation of multicellular organismal process GO:0051241 317 0.043
regulation of cell cycle GO:0051726 393 0.043
regulation of proteolysis GO:0030162 293 0.043
positive regulation of protein phosphorylation GO:0001934 313 0.043
cell projection morphogenesis GO:0048858 129 0.042
nucleoside triphosphate catabolic process GO:0009143 394 0.042
chromatin assembly or disassembly GO:0006333 78 0.042
triglyceride biosynthetic process GO:0019432 10 0.041
neuron differentiation GO:0030182 138 0.040
regulation of mapk cascade GO:0043408 262 0.039
positive regulation of mapk cascade GO:0043410 190 0.039
regulation of epithelial cell proliferation GO:0050678 113 0.039
generation of neurons GO:0048699 152 0.039
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.039
cellular response to oxidative stress GO:0034599 85 0.039
organophosphate catabolic process GO:0046434 430 0.038
cellular response to radiation GO:0071478 65 0.038
positive regulation of kinase activity GO:0033674 204 0.038
positive regulation of phosphorylation GO:0042327 394 0.038
face development GO:0060324 12 0.037
purine ribonucleotide catabolic process GO:0009154 404 0.037
cellular protein catabolic process GO:0044257 261 0.037
regulation of protein maturation GO:1903317 150 0.036
protein processing GO:0016485 226 0.036
positive regulation of transferase activity GO:0051347 227 0.035
protein dna complex subunit organization GO:0071824 80 0.035
regulation of chromosome organization GO:0033044 103 0.035
dna replication dependent nucleosome assembly GO:0006335 32 0.035
rna processing GO:0006396 255 0.035
purine nucleoside triphosphate catabolic process GO:0009146 392 0.034
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.033
maintenance of location GO:0051235 112 0.032
apoptotic signaling pathway GO:0097190 268 0.032
response to abiotic stimulus GO:0009628 336 0.032
enzyme linked receptor protein signaling pathway GO:0007167 303 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.031
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.031
regulation of notch signaling pathway GO:0008593 18 0.031
ribonucleotide catabolic process GO:0009261 405 0.031
regulation of nucleoside metabolic process GO:0009118 209 0.030
rna splicing GO:0008380 131 0.030
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.030
ribonucleoside triphosphate catabolic process GO:0009203 391 0.030
cell morphogenesis involved in differentiation GO:0000904 144 0.029
ribonucleoside triphosphate metabolic process GO:0009199 412 0.029
protein complex disassembly GO:0043241 52 0.029
dna replication independent nucleosome assembly GO:0006336 27 0.029
glycerolipid metabolic process GO:0046486 107 0.029
negative regulation of cell cycle GO:0045786 193 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
nucleoside catabolic process GO:0009164 408 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.028
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
lipid biosynthetic process GO:0008610 177 0.027
cellular lipid metabolic process GO:0044255 303 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
regulation of dna templated transcription elongation GO:0032784 23 0.026
positive regulation of catabolic process GO:0009896 310 0.026
dna templated transcription elongation GO:0006354 25 0.025
regulation of response to oxidative stress GO:1902882 26 0.025
atp catabolic process GO:0006200 157 0.024
peptidyl tyrosine modification GO:0018212 170 0.024
atp dependent chromatin remodeling GO:0043044 25 0.024
posttranscriptional regulation of gene expression GO:0010608 213 0.024
response to metal ion GO:0010038 84 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
internal peptidyl lysine acetylation GO:0018393 97 0.024
response to cytokine GO:0034097 232 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.023
negative regulation of cell proliferation GO:0008285 228 0.023
nervous system development GO:0007399 293 0.023
response to external biotic stimulus GO:0043207 261 0.023
protein stabilization GO:0050821 64 0.022
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902177 4 0.022
reproductive process GO:0022414 106 0.022
regulation of protein acetylation GO:1901983 25 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
negative regulation of protein maturation GO:1903318 142 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
regulation of dna dependent dna replication initiation GO:0030174 3 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
positive regulation of organelle organization GO:0010638 195 0.021
epithelial cell proliferation GO:0050673 128 0.021
regulation of mrna splicing via spliceosome GO:0048024 32 0.020
regulation of cell cycle process GO:0010564 266 0.020
neurogenesis GO:0022008 169 0.020
dna geometric change GO:0032392 32 0.020
response to radiation GO:0009314 151 0.020
mapk cascade GO:0000165 288 0.020
embryo development ending in birth or egg hatching GO:0009792 34 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
growth GO:0040007 202 0.020
intrinsic apoptotic signaling pathway GO:0097193 127 0.020
peripheral nervous system development GO:0007422 2 0.019
cell cycle dna replication GO:0044786 11 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
mrna metabolic process GO:0016071 175 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.019
positive regulation of cellular component biogenesis GO:0044089 158 0.018
engulfment of apoptotic cell GO:0043652 2 0.018
negative regulation of catabolic process GO:0009895 104 0.018
regulation of erk1 and erk2 cascade GO:0070372 99 0.018
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.018
vesicle mediated transport GO:0016192 371 0.018
regulation of histone modification GO:0031056 47 0.018
transmembrane transport GO:0055085 399 0.018
macromolecule methylation GO:0043414 97 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
guanosine containing compound catabolic process GO:1901069 239 0.017
internal protein amino acid acetylation GO:0006475 101 0.017
regulation of cellular protein catabolic process GO:1903362 96 0.017
sister chromatid cohesion GO:0007062 24 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
nuclear division GO:0000280 128 0.017
neuromuscular junction development GO:0007528 3 0.017
erk1 and erk2 cascade GO:0070371 104 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
cellular component morphogenesis GO:0032989 314 0.017
dna packaging GO:0006323 77 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.017
neuron projection development GO:0031175 106 0.017
negative regulation of protein metabolic process GO:0051248 391 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.016
positive regulation of protein catabolic process GO:0045732 75 0.016
protein methylation GO:0006479 74 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.016
atp metabolic process GO:0046034 176 0.016
ion transmembrane transport GO:0034220 338 0.016
gtp catabolic process GO:0006184 237 0.016
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.016
chromatin modification GO:0016568 298 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
regulation of triglyceride metabolic process GO:0090207 11 0.016
regulation of dna templated transcription in response to stress GO:0043620 18 0.016
negative regulation of hydrolase activity GO:0051346 182 0.015
biological adhesion GO:0022610 331 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
regulation of receptor activity GO:0010469 47 0.015
cell projection assembly GO:0030031 126 0.015
nucleotide catabolic process GO:0009166 408 0.015
regeneration GO:0031099 4 0.015
chromatin remodeling GO:0006338 55 0.015
response to biotic stimulus GO:0009607 276 0.015
protein autophosphorylation GO:0046777 123 0.015
response to ionizing radiation GO:0010212 65 0.015
regulation of protein tyrosine kinase activity GO:0061097 36 0.015
histone ubiquitination GO:0016574 31 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.015
hepatocyte proliferation GO:0072574 1 0.015
positive regulation of cellular response to oxidative stress GO:1900409 7 0.015
negative regulation of epithelial cell proliferation GO:0050680 48 0.015
actin filament based process GO:0030029 224 0.015
membrane organization GO:0061024 292 0.014
neuron death in response to oxidative stress GO:0036475 9 0.014
embryo development GO:0009790 123 0.014
response to other organism GO:0051707 261 0.014
nucleosome organization GO:0034728 66 0.014
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
locomotory behavior GO:0007626 1 0.014
gtp metabolic process GO:0046039 239 0.014
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 8 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
meiotic chromosome segregation GO:0045132 4 0.014
negative regulation of transferase activity GO:0051348 124 0.014
myeloid cell differentiation GO:0030099 117 0.014
cell development GO:0048468 328 0.014
regulation of lipid metabolic process GO:0019216 96 0.014
g1 s transition of mitotic cell cycle GO:0000082 78 0.013
dendrite development GO:0016358 24 0.013
face morphogenesis GO:0060325 10 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 7 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.013
negative regulation of developmental process GO:0051093 247 0.013
cellular response to sterol depletion GO:0071501 4 0.013
tube development GO:0035295 125 0.013
cell adhesion GO:0007155 325 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
regulation of cellular response to oxidative stress GO:1900407 26 0.013
regulation of mrna processing GO:0050684 48 0.013
notch signaling pathway GO:0007219 31 0.013
modification dependent protein catabolic process GO:0019941 209 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
liver morphogenesis GO:0072576 1 0.012
regulation of gene silencing GO:0060968 24 0.012
mitotic nuclear division GO:0007067 119 0.012
negative regulation of immune system process GO:0002683 136 0.012
cell cycle g2 m phase transition GO:0044839 43 0.012
cell type specific apoptotic process GO:0097285 125 0.012
regulation of protein stability GO:0031647 87 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
regulation of cellular response to stress GO:0080135 244 0.012
regulation of neuron death GO:1901214 56 0.012
protein acetylation GO:0006473 116 0.012
reproduction GO:0000003 63 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
cell death in response to oxidative stress GO:0036473 29 0.012
protein localization to organelle GO:0033365 280 0.012
mitotic cell cycle process GO:1903047 286 0.012
metal ion transport GO:0030001 272 0.011
hemopoiesis GO:0030097 180 0.011
cell cycle phase transition GO:0044770 173 0.011
sister chromatid segregation GO:0000819 54 0.011
neuron remodeling GO:0016322 2 0.011
response to light stimulus GO:0009416 87 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
dephosphorylation GO:0016311 209 0.011
positive regulation of cellular protein catabolic process GO:1903364 37 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
lipid localization GO:0010876 106 0.011
defense response GO:0006952 315 0.011
defense response to other organism GO:0098542 129 0.011
cell growth GO:0016049 160 0.011
cellular component disassembly GO:0022411 92 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
cellular response to light stimulus GO:0071482 34 0.011
cation transport GO:0006812 331 0.011
covalent chromatin modification GO:0016569 254 0.010
oxidation reduction process GO:0055114 396 0.010
developmental process involved in reproduction GO:0003006 66 0.010
rho protein signal transduction GO:0007266 26 0.010
head morphogenesis GO:0060323 11 0.010
immune response GO:0006955 307 0.010
regulation of anatomical structure size GO:0090066 101 0.010
mitotic cell cycle GO:0000278 326 0.010
response to oxidative stress GO:0006979 121 0.010
protein maturation GO:0051604 233 0.010

MMS22L disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.068
disease of metabolism DOID:0014667 295 0.063
hematopoietic system disease DOID:74 100 0.035
inherited metabolic disorder DOID:655 242 0.022
sensory system disease DOID:0050155 203 0.015
nervous system disease DOID:863 431 0.015
eye and adnexa disease DOID:1492 150 0.014
cancer DOID:162 167 0.011
disease of cellular proliferation DOID:14566 174 0.011
organ system cancer DOID:0050686 164 0.011