Homo sapiens

0 known processes

MSH5

mutS homolog 5 (E. coli)

(Aliases: G7,NG23,DKFZp434C1615,MUTSH5,MGC2939)

MSH5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiosis i GO:0007127 4 0.830
Yeast Mouse Worm
reciprocal meiotic recombination GO:0007131 4 0.737
Yeast Worm
reciprocal dna recombination GO:0035825 4 0.618
Yeast Worm
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.565
organelle fission GO:0048285 149 0.508
Yeast Mouse Worm
regulation of phagocytosis engulfment GO:0060099 2 0.435
negative regulation of phagocytosis engulfment GO:0060101 1 0.433
ras protein signal transduction GO:0007265 73 0.369
endomembrane system organization GO:0010256 196 0.224
neuromuscular junction development GO:0007528 3 0.146
regulation of interleukin 2 secretion GO:1900040 2 0.129
purine ribonucleotide catabolic process GO:0009154 404 0.124
meiotic nuclear division GO:0007126 10 0.114
Yeast Mouse Worm
cellular response to dna damage stimulus GO:0006974 379 0.114
purine ribonucleoside metabolic process GO:0046128 437 0.113
cell development GO:0048468 328 0.108
calcium ion transport GO:0006816 147 0.103
regulation of mitotic cell cycle GO:0007346 189 0.098
regulation of actin cytoskeleton organization GO:0032956 116 0.089
membrane organization GO:0061024 292 0.084
small gtpase mediated signal transduction GO:0007264 78 0.081
positive regulation of organelle organization GO:0010638 195 0.080
meiotic cell cycle GO:0051321 13 0.078
Yeast Mouse Worm
cellular ketone metabolic process GO:0042180 80 0.074
regulation of non canonical wnt signaling pathway GO:2000050 4 0.074
chromatin organization GO:0006325 351 0.073
dna conformation change GO:0071103 113 0.069
nucleoside triphosphate catabolic process GO:0009143 394 0.068
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.067
dna repair GO:0006281 198 0.066
regulation of cell cycle phase transition GO:1901987 126 0.063
female gamete generation GO:0007292 2 0.063
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.062
oocyte differentiation GO:0009994 2 0.062
negative regulation of phosphate metabolic process GO:0045936 267 0.060
multicellular organismal aging GO:0010259 3 0.060
divalent inorganic cation transport GO:0072511 158 0.060
post embryonic development GO:0009791 2 0.059
Worm
engulfment of apoptotic cell GO:0043652 2 0.059
regulation of cytoskeleton organization GO:0051493 177 0.058
nucleoside phosphate catabolic process GO:1901292 412 0.057
oogenesis GO:0048477 2 0.057
regulation of actin filament based process GO:0032970 141 0.055
mitochondrion organization GO:0007005 156 0.055
positive regulation of cell cycle GO:0045787 140 0.055
positive regulation of phosphorylation GO:0042327 394 0.054
cation transport GO:0006812 331 0.054
interleukin 2 secretion GO:0070970 3 0.053
purine nucleoside catabolic process GO:0006152 398 0.053
positive regulation of cellular component organization GO:0051130 376 0.052
metal ion transport GO:0030001 272 0.052
negative regulation of phosphorus metabolic process GO:0010563 267 0.051
determination of adult lifespan GO:0008340 2 0.051
rac protein signal transduction GO:0016601 12 0.049
segmentation GO:0035282 4 0.048
mitotic cell cycle GO:0000278 326 0.047
positive regulation of phagocytosis engulfment GO:0060100 1 0.047
negative regulation of mitotic cell cycle GO:0045930 102 0.047
negative regulation of cell cycle process GO:0010948 121 0.046
organophosphate catabolic process GO:0046434 430 0.046
negative regulation of cellular protein metabolic process GO:0032269 353 0.046
thymus development GO:0048538 3 0.045
golgi organization GO:0007030 38 0.045
negative regulation of phosphorylation GO:0042326 174 0.044
mitotic cell cycle process GO:1903047 286 0.044
apoptotic signaling pathway GO:0097190 268 0.044
intrinsic apoptotic signaling pathway GO:0097193 127 0.043
actin cytoskeleton organization GO:0030036 207 0.042
purine nucleotide catabolic process GO:0006195 405 0.042
guanosine containing compound catabolic process GO:1901069 239 0.041
vesicle mediated transport GO:0016192 371 0.041
defense response GO:0006952 315 0.041
mapk cascade GO:0000165 288 0.040
regulation of cellular response to stress GO:0080135 244 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
regulation of mapk cascade GO:0043408 262 0.040
regulation of cell cycle GO:0051726 393 0.040
protein modification by small protein conjugation GO:0032446 342 0.039
glycosyl compound catabolic process GO:1901658 413 0.039
circulatory system process GO:0003013 113 0.038
oocyte development GO:0048599 1 0.037
positive regulation of transport GO:0051050 336 0.037
regulation of nucleoside metabolic process GO:0009118 209 0.037
regulation of establishment of protein localization GO:0070201 242 0.036
cellular amine metabolic process GO:0044106 41 0.035
ribonucleoside catabolic process GO:0042454 406 0.035
divalent metal ion transport GO:0070838 152 0.035
regulation of cellular amine metabolic process GO:0033238 11 0.035
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.033
positive regulation of wnt signaling pathway planar cell polarity pathway GO:2000096 2 0.033
meiotic chromosome segregation GO:0045132 4 0.032
Worm
negative regulation of phagocytosis GO:0050765 4 0.032
positive regulation of cellular component biogenesis GO:0044089 158 0.032
regulation of cellular component biogenesis GO:0044087 281 0.032
positive regulation of calcium ion transport GO:0051928 51 0.031
regulation of purine nucleotide catabolic process GO:0033121 205 0.031
immune response activating signal transduction GO:0002757 90 0.031
negative regulation of mapk cascade GO:0043409 56 0.031
positive regulation of apoptotic process GO:0043065 246 0.030
signal transduction by p53 class mediator GO:0072331 72 0.030
axon extension involved in axon guidance GO:0048846 5 0.030
purine ribonucleoside catabolic process GO:0046130 398 0.030
cell cycle checkpoint GO:0000075 117 0.030
regulation of ras gtpase activity GO:0032318 128 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
ribonucleotide catabolic process GO:0009261 405 0.029
signal transduction by phosphorylation GO:0023014 297 0.029
regulation of response to dna damage stimulus GO:2001020 94 0.029
mitotic cell cycle checkpoint GO:0007093 68 0.028
positive regulation of gtp catabolic process GO:0033126 166 0.028
guanosine containing compound metabolic process GO:1901068 244 0.028
dna packaging GO:0006323 77 0.028
establishment of planar polarity GO:0001736 3 0.027
cell growth GO:0016049 160 0.027
response to biotic stimulus GO:0009607 276 0.027
secretion by cell GO:0032940 226 0.027
actin filament based process GO:0030029 224 0.027
regulation of kinase activity GO:0043549 314 0.027
regulation of protein localization GO:0032880 296 0.027
sequestering of metal ion GO:0051238 24 0.027
negative regulation of cell death GO:0060548 345 0.027
regulation of cell cycle process GO:0010564 266 0.026
positive regulation of extracellular matrix organization GO:1903055 3 0.026
actin filament polymerization GO:0030041 45 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
negative regulation of cell cycle GO:0045786 193 0.026
regulation of mitotic cell cycle phase transition GO:1901990 118 0.026
positive regulation of nucleoside metabolic process GO:0045979 186 0.025
negative regulation of cell cycle phase transition GO:1901988 89 0.025
jnk cascade GO:0007254 80 0.025
regulation of cell migration GO:0030334 289 0.025
reproduction GO:0000003 63 0.025
Yeast Mouse Worm
regulation of oxidative stress induced cell death GO:1903201 24 0.025
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
cerebellum development GO:0021549 2 0.025
defense response to bacterium GO:0042742 63 0.025
regulation of apoptotic cell clearance GO:2000425 5 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
regulation of neural precursor cell proliferation GO:2000177 4 0.024
gtp catabolic process GO:0006184 237 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
regulation of ion transport GO:0043269 189 0.024
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.024
viral life cycle GO:0019058 132 0.024
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.024
metencephalon development GO:0022037 2 0.024
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.024
phospholipid metabolic process GO:0006644 99 0.024
motor neuron axon guidance GO:0008045 2 0.023
positive regulation of ras gtpase activity GO:0032320 117 0.023
cell adhesion GO:0007155 325 0.023
chromatin assembly or disassembly GO:0006333 78 0.023
purine containing compound catabolic process GO:0072523 411 0.023
central nervous system development GO:0007417 123 0.022
muscle organ development GO:0007517 56 0.022
cellular response to abiotic stimulus GO:0071214 117 0.022
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.022
b cell proliferation GO:0042100 22 0.022
nuclear division GO:0000280 128 0.022
Yeast Mouse Worm
negative regulation of viral process GO:0048525 66 0.022
central nervous system neuron axonogenesis GO:0021955 3 0.022
endocytosis GO:0006897 159 0.021
regulation of cell morphogenesis GO:0022604 153 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
dna damage checkpoint GO:0000077 68 0.021
cellular protein complex assembly GO:0043623 188 0.021
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
response to endoplasmic reticulum stress GO:0034976 49 0.021
actin filament organization GO:0007015 128 0.021
cell projection organization GO:0030030 252 0.021
regulation of protein complex assembly GO:0043254 147 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
negative regulation of apoptotic process GO:0043066 316 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
negative regulation of kinase activity GO:0033673 106 0.021
response to fungus GO:0009620 4 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.020
compound eye development GO:0048749 1 0.020
regulation of protein maturation GO:1903317 150 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
chromosome segregation GO:0007059 114 0.020
Worm
regulation of chromosome organization GO:0033044 103 0.019
i kappab kinase nf kappab signaling GO:0007249 166 0.019
regulation of cell cycle arrest GO:0071156 36 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
regulation of actin filament length GO:0030832 56 0.019
regulation of viral process GO:0050792 103 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
mrna metabolic process GO:0016071 175 0.019
response to bacterium GO:0009617 144 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.018
growth GO:0040007 202 0.018
axis elongation GO:0003401 4 0.018
nerve development GO:0021675 4 0.018
dna integrity checkpoint GO:0031570 71 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
multi organism cellular process GO:0044764 156 0.018
erk1 and erk2 cascade GO:0070371 104 0.018
cell morphogenesis GO:0000902 296 0.018
defense response to fungus GO:0050832 4 0.018
negative regulation of multi organism process GO:0043901 92 0.017
biological adhesion GO:0022610 331 0.017
nucleotide catabolic process GO:0009166 408 0.017
cell substrate adhesion GO:0031589 132 0.017
actin nucleation GO:0045010 21 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
ion homeostasis GO:0050801 230 0.017
rna processing GO:0006396 255 0.017
negative regulation of jnk cascade GO:0046329 16 0.017
cell cycle arrest GO:0007050 71 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
nucleoside catabolic process GO:0009164 408 0.017
developmental growth involved in morphogenesis GO:0060560 23 0.016
generation of neurons GO:0048699 152 0.016
negative regulation of transport GO:0051051 176 0.016
defense response to other organism GO:0098542 129 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
signal transduction in response to dna damage GO:0042770 57 0.016
cellular response to oxidative stress GO:0034599 85 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
response to abiotic stimulus GO:0009628 336 0.016
neurological system process GO:0050877 163 0.016
regulation of proteolysis GO:0030162 293 0.016
response to organonitrogen compound GO:0010243 156 0.016
negative regulation of organelle organization GO:0010639 126 0.016
protein processing GO:0016485 226 0.016
regulation of protein transport GO:0051223 213 0.016
regulation of cellular component size GO:0032535 82 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
protein maturation GO:0051604 233 0.016
cytosolic calcium ion homeostasis GO:0051480 89 0.015
response to uv GO:0009411 73 0.015
protein localization to organelle GO:0033365 280 0.015
nervous system development GO:0007399 293 0.015
negative regulation of stress activated mapk cascade GO:0032873 19 0.015
protein targeting GO:0006605 187 0.015
positive regulation of wnt signaling pathway GO:0030177 54 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
regulation of gtpase activity GO:0043087 180 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
negative regulation of protein modification process GO:0031400 200 0.014
positive regulation of mitotic cell cycle GO:0045931 60 0.014
protein acetylation GO:0006473 116 0.014
regulation of cellular senescence GO:2000772 13 0.014
lipid metabolic process GO:0006629 381 0.014
single organism membrane organization GO:0044802 268 0.014
spermatid differentiation GO:0048515 4 0.014
regulation of neuron death GO:1901214 56 0.014
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.014
cellular metal ion homeostasis GO:0006875 146 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
protein acylation GO:0043543 138 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
positive regulation of cytoplasmic transport GO:1903651 82 0.014
regulation of protein kinase activity GO:0045859 289 0.014
mitotic dna damage checkpoint GO:0044773 28 0.014
regulation of stress activated mapk cascade GO:0032872 84 0.014
positive regulation of rho gtpase activity GO:0032321 56 0.014
positive regulation of catabolic process GO:0009896 310 0.014
cognition GO:0050890 43 0.014
intracellular protein transport GO:0006886 270 0.014
neuron projection development GO:0031175 106 0.014
neuron death GO:0070997 65 0.014
hindbrain development GO:0030902 3 0.014
regulation of anatomical structure size GO:0090066 101 0.013
response to external biotic stimulus GO:0043207 261 0.013
actin filament bundle assembly GO:0051017 54 0.013
transmembrane transport GO:0055085 399 0.013
astrocyte differentiation GO:0048708 4 0.013
single organismal cell cell adhesion GO:0016337 148 0.013
cell cycle phase transition GO:0044770 173 0.013
regulation of cell growth GO:0001558 135 0.013
cytoplasmic transport GO:0016482 379 0.013
amine metabolic process GO:0009308 44 0.013
microtubule based process GO:0007017 210 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
positive regulation of cell cycle arrest GO:0071158 23 0.013
establishment of tissue polarity GO:0007164 3 0.013
neurogenesis GO:0022008 169 0.013
response to light stimulus GO:0009416 87 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
response to radiation GO:0009314 151 0.013
negative regulation of erk1 and erk2 cascade GO:0070373 14 0.013
response to organic cyclic compound GO:0014070 204 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
actin polymerization or depolymerization GO:0008154 56 0.013
negative regulation of response to dna damage stimulus GO:2001021 33 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 5 0.013
regulation of mitochondrion organization GO:0010821 54 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
regulation of defense response GO:0031347 154 0.013
somitogenesis GO:0001756 2 0.013
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.012
regulation of actin polymerization or depolymerization GO:0008064 56 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.012
positive regulation of phagocytosis GO:0050766 15 0.012
regulation of secretion GO:0051046 194 0.012
ion transmembrane transport GO:0034220 338 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
positive regulation of protein complex assembly GO:0031334 86 0.012
gtp metabolic process GO:0046039 239 0.012
response to nitrogen compound GO:1901698 184 0.012
regulation of protein stability GO:0031647 87 0.012
chromatin modification GO:0016568 298 0.012
negative regulation of cell migration GO:0030336 102 0.012
cellular lipid metabolic process GO:0044255 303 0.012
protein catabolic process GO:0030163 325 0.012
regulation of protein processing GO:0070613 150 0.012
spermatid development GO:0007286 4 0.012
interspecies interaction between organisms GO:0044419 156 0.012
negative regulation of phospholipase activity GO:0010519 3 0.012
positive regulation of osteoblast proliferation GO:0033690 3 0.012
positive regulation of homeostatic process GO:0032846 47 0.012
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.012
innate immune response GO:0045087 178 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
regulation of actin filament polymerization GO:0030833 50 0.011
negative regulation of immune system process GO:0002683 136 0.011
internal peptidyl lysine acetylation GO:0018393 97 0.011
peripheral nervous system development GO:0007422 2 0.011
cellular response to radiation GO:0071478 65 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.011
nuclear transport GO:0051169 179 0.011
maintenance of location GO:0051235 112 0.011
reproductive process GO:0022414 106 0.011
Mouse
single organism reproductive process GO:0044702 98 0.011
Mouse
parathyroid gland development GO:0060017 2 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
regulation of cell cycle g1 s phase transition GO:1902806 42 0.011
regeneration GO:0031099 4 0.011
regulation of homeostatic process GO:0032844 121 0.011
negative regulation of transferase activity GO:0051348 124 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
peptidyl lysine modification GO:0018205 144 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
positive regulation of actin filament polymerization GO:0030838 38 0.011
phagocytosis GO:0006909 42 0.011
macromolecule methylation GO:0043414 97 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
negative regulation of homeostatic process GO:0032845 59 0.011
stress activated mapk cascade GO:0051403 93 0.011
response to wounding GO:0009611 168 0.011
taxis GO:0042330 157 0.011
inner ear morphogenesis GO:0042472 4 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
covalent chromatin modification GO:0016569 254 0.010
regulation of system process GO:0044057 101 0.010
regulation of calcium ion transport into cytosol GO:0010522 33 0.010
blood circulation GO:0008015 113 0.010
oxidative stress induced premature senescence GO:0090403 3 0.010
response to oxygen levels GO:0070482 100 0.010
positive regulation of cell death GO:0010942 263 0.010
phagocytosis engulfment GO:0006911 7 0.010
regulation of signal transduction by p53 class mediator GO:1901796 26 0.010
lamellipodium organization GO:0097581 30 0.010
cellular protein catabolic process GO:0044257 261 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
negative regulation of sequestering of calcium ion GO:0051283 41 0.010
regulation of protein localization to nucleus GO:1900180 85 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
peptidyl lysine acetylation GO:0018394 101 0.010
positive regulation of ion transport GO:0043270 87 0.010
axonogenesis GO:0007409 31 0.010
cell projection morphogenesis GO:0048858 129 0.010

MSH5 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.023
disease of cellular proliferation DOID:14566 174 0.023
organ system cancer DOID:0050686 164 0.023
sensory system disease DOID:0050155 203 0.013
eye and adnexa disease DOID:1492 150 0.013
nervous system disease DOID:863 431 0.013
disease of metabolism DOID:0014667 295 0.010
inherited metabolic disorder DOID:655 242 0.010