Homo sapiens

138 known processes

MTOR

mechanistic target of rapamycin (serine/threonine kinase)

(Aliases: RAFT1,FRAP1,FRAP2,FLJ44809,RAPT1,FRAP)

MTOR biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of tor signaling GO:0032006 30 1.000
tor signaling GO:0031929 39 1.000
positive regulation of tor signaling GO:0032008 11 1.000
positive regulation of cell size GO:0045793 3 1.000
Fly
positive regulation of protein phosphorylation GO:0001934 313 0.998
rho protein signal transduction GO:0007266 26 0.997
Yeast
ribonucleotide catabolic process GO:0009261 405 0.997
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.996
Yeast Mouse Fly
glycosyl compound catabolic process GO:1901658 413 0.987
Mouse
guanosine containing compound metabolic process GO:1901068 244 0.986
Mouse
purine containing compound catabolic process GO:0072523 411 0.985
Mouse
amine metabolic process GO:0009308 44 0.985
purine ribonucleotide catabolic process GO:0009154 404 0.985
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.984
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.984
positive regulation of phosphorylation GO:0042327 394 0.984
purine ribonucleoside catabolic process GO:0046130 398 0.981
Mouse
negative regulation of cell size GO:0045792 3 0.978
Mouse Rat
ribonucleoside catabolic process GO:0042454 406 0.978
Mouse
organophosphate catabolic process GO:0046434 430 0.978
Mouse
regulation of nucleotide catabolic process GO:0030811 205 0.976
Yeast Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.974
Mouse
gtp metabolic process GO:0046039 239 0.973
Mouse
negative regulation of phosphorylation GO:0042326 174 0.972
nucleoside phosphate catabolic process GO:1901292 412 0.969
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.968
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.956
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.951
Mouse
regulation of translation GO:0006417 89 0.941
regulation of ras gtpase activity GO:0032318 128 0.941
Yeast Mouse
regulation of rho protein signal transduction GO:0035023 79 0.937
Yeast Mouse
negative regulation of tor signaling GO:0032007 11 0.936
nucleoside catabolic process GO:0009164 408 0.931
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.925
regulation of anatomical structure size GO:0090066 101 0.925
Mouse Rat Fly
negative regulation of protein modification process GO:0031400 200 0.914
nucleotide catabolic process GO:0009166 408 0.904
Mouse
regulation of purine nucleotide catabolic process GO:0033121 205 0.904
Yeast Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.899
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.898
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.891
cellular macromolecular complex assembly GO:0034622 324 0.891
Mouse
ras protein signal transduction GO:0007265 73 0.887
Yeast
positive regulation of cellular amine metabolic process GO:0033240 7 0.873
regulation of ras protein signal transduction GO:0046578 155 0.872
Yeast Mouse
autophagy GO:0006914 88 0.869
Yeast Mouse Fly
positive regulation of protein kinase activity GO:0045860 190 0.857
neuromuscular junction development GO:0007528 3 0.852
Fly
chemotaxis GO:0006935 157 0.850
Fly
regulation of reactive oxygen species metabolic process GO:2000377 41 0.849
Fly
purine nucleotide catabolic process GO:0006195 405 0.847
Mouse
regulation of transferase activity GO:0051338 355 0.841
Mouse
purine nucleoside catabolic process GO:0006152 398 0.840
Mouse
negative regulation of kinase activity GO:0033673 106 0.823
response to radiation GO:0009314 151 0.821
Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.820
Mouse
regulation of nucleotide metabolic process GO:0006140 269 0.812
Yeast Mouse
regulation of apoptotic signaling pathway GO:2001233 175 0.801
cellular response to nitrogen compound GO:1901699 144 0.797
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.792
regulation of cell growth GO:0001558 135 0.781
Yeast Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.773
positive regulation of transferase activity GO:0051347 227 0.773
response to nutrient levels GO:0031667 81 0.772
Mouse Rat Fly
cellular amine metabolic process GO:0044106 41 0.772
cell cycle phase transition GO:0044770 173 0.764
negative regulation of transferase activity GO:0051348 124 0.744
negative regulation of protein phosphorylation GO:0001933 140 0.738
extrinsic apoptotic signaling pathway GO:0097191 119 0.734
cell development GO:0048468 328 0.730
Mouse Fly
cellular response to external stimulus GO:0071496 111 0.701
Mouse Fly
regulation of protein serine threonine kinase activity GO:0071900 179 0.696
regulation of nucleoside metabolic process GO:0009118 209 0.696
Yeast Mouse
response to starvation GO:0042594 59 0.694
Mouse Fly
response to extracellular stimulus GO:0009991 85 0.681
Mouse Rat Fly
carbohydrate metabolic process GO:0005975 207 0.678
Rat
regulation of protein kinase activity GO:0045859 289 0.675
Mouse
regulation of growth GO:0040008 165 0.675
Yeast Fly
gtp catabolic process GO:0006184 237 0.668
Mouse
apoptotic signaling pathway GO:0097190 268 0.657
regulation of cell morphogenesis GO:0022604 153 0.646
regulation of cellular component size GO:0032535 82 0.631
Mouse Rat Fly
peptidyl tyrosine phosphorylation GO:0018108 170 0.630
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.620
positive regulation of transcription from rna polymerase iii promoter GO:0045945 10 0.609
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.604
cellular response to starvation GO:0009267 58 0.600
Mouse Fly
regulation of purine nucleotide metabolic process GO:1900542 264 0.600
Yeast Mouse
cellular amino acid metabolic process GO:0006520 116 0.599
cellular response to oxygen containing compound GO:1901701 276 0.584
cell activation GO:0001775 213 0.554
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.548
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.548
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.546
regulation of gtpase activity GO:0043087 180 0.543
Yeast Mouse
regulation of kinase activity GO:0043549 314 0.542
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.538
Yeast
regulation of cellular amino acid metabolic process GO:0006521 6 0.529
translational initiation GO:0006413 48 0.526
Yeast
regulation of cellular component movement GO:0051270 334 0.519
cellular ketone metabolic process GO:0042180 80 0.517
Rat
reactive oxygen species metabolic process GO:0072593 75 0.509
Fly
response to organonitrogen compound GO:0010243 156 0.491
positive regulation of actin filament polymerization GO:0030838 38 0.488
Mouse
negative regulation of t cell apoptotic process GO:0070233 4 0.487
positive regulation of cellular component organization GO:0051130 376 0.486
Yeast Mouse
regulation of actin filament polymerization GO:0030833 50 0.482
Mouse
negative regulation of catalytic activity GO:0043086 335 0.477
t cell activation GO:0042110 99 0.470
positive regulation of cellular component biogenesis GO:0044089 158 0.457
Mouse Fly
actin filament based process GO:0030029 224 0.455
regulation of small gtpase mediated signal transduction GO:0051056 156 0.448
Yeast Mouse
growth GO:0040007 202 0.447
cellular component morphogenesis GO:0032989 314 0.443
Fly
regulation of locomotion GO:0040012 329 0.442
regulation of cellular ketone metabolic process GO:0010565 50 0.435
Rat
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.419
cellular response to insulin stimulus GO:0032869 41 0.418
regulation of gtp catabolic process GO:0033124 180 0.414
Yeast Mouse
negative regulation of cellular component organization GO:0051129 235 0.408
cell cycle g1 s phase transition GO:0044843 80 0.405
guanosine containing compound catabolic process GO:1901069 239 0.404
Mouse
amino acid transport GO:0006865 28 0.403
mitotic cell cycle process GO:1903047 286 0.390
positive regulation of rac gtpase activity GO:0032855 31 0.378
negative regulation of autophagy GO:0010507 14 0.373
Yeast Mouse Fly
g1 s transition of mitotic cell cycle GO:0000082 78 0.368
response to abiotic stimulus GO:0009628 336 0.367
Mouse Fly
cellular response to nutrient levels GO:0031669 69 0.364
Mouse Fly
cell growth GO:0016049 160 0.363
regulation of anatomical structure morphogenesis GO:0022603 286 0.362
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.361
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.359
Mouse
maintenance of location GO:0051235 112 0.356
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.355
synapse assembly GO:0007416 8 0.353
Fly
translation GO:0006412 132 0.350
lipid localization GO:0010876 106 0.348
cell chemotaxis GO:0060326 112 0.343
cell morphogenesis involved in differentiation GO:0000904 144 0.342
Fly
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.338
positive regulation of hydrolase activity GO:0051345 331 0.336
Yeast
neuron development GO:0048666 113 0.329
Fly
transmission of nerve impulse GO:0019226 11 0.320
regulation of protein complex assembly GO:0043254 147 0.319
Mouse
carboxylic acid transport GO:0046942 63 0.318
positive regulation of kinase activity GO:0033674 204 0.312
regulation of transmembrane transport GO:0034762 139 0.311
calcium ion homeostasis GO:0055074 122 0.308
phospholipid catabolic process GO:0009395 12 0.307
regulation of cellular amine metabolic process GO:0033238 11 0.303
peptidyl serine phosphorylation GO:0018105 101 0.301
actin filament organization GO:0007015 128 0.297
Mouse
post embryonic development GO:0009791 2 0.294
negative regulation of ion transport GO:0043271 39 0.293
retrograde transport endosome to golgi GO:0042147 45 0.288
negative regulation of cellular catabolic process GO:0031330 83 0.285
Yeast Mouse Fly
taxis GO:0042330 157 0.281
Fly
lipid metabolic process GO:0006629 381 0.265
neurological system process GO:0050877 163 0.263
positive regulation of protein polymerization GO:0032273 45 0.258
Mouse
cellular protein complex assembly GO:0043623 188 0.257
Mouse
positive regulation of protein complex assembly GO:0031334 86 0.255
Mouse
neutrophil chemotaxis GO:0030593 24 0.245
metal ion homeostasis GO:0055065 169 0.243
regulation of rho gtpase activity GO:0032319 66 0.242
Yeast Mouse
regulation of cell development GO:0060284 161 0.228
protein ubiquitination GO:0016567 314 0.227
regulation of cell differentiation GO:0045595 393 0.225
Mouse
fibroblast migration GO:0010761 7 0.224
granulocyte chemotaxis GO:0071621 37 0.223
regulation of cell size GO:0008361 19 0.222
Mouse Rat Fly
cell adhesion GO:0007155 325 0.216
i kappab kinase nf kappab signaling GO:0007249 166 0.216
cation homeostasis GO:0055080 189 0.214
lipid modification GO:0030258 84 0.213
Rat
cellular response to peptide GO:1901653 59 0.210
response to organic cyclic compound GO:0014070 204 0.206
anion transport GO:0006820 161 0.206
negative regulation of protein kinase activity GO:0006469 98 0.205
regulation of glucosylceramide catabolic process GO:2000752 1 0.205
positive regulation of nucleotide metabolic process GO:0045981 230 0.202
Yeast
glucosylceramide metabolic process GO:0006678 3 0.200
positive regulation of interleukin 5 production GO:0032754 3 0.198
neuron differentiation GO:0030182 138 0.192
Fly
regulation of cytoskeleton organization GO:0051493 177 0.190
response to oxygen containing compound GO:1901700 369 0.188
negative regulation of hydrolase activity GO:0051346 182 0.187
leukocyte chemotaxis GO:0030595 76 0.186
neuron projection development GO:0031175 106 0.185
Fly
response to amino acid GO:0043200 14 0.184
small gtpase mediated signal transduction GO:0007264 78 0.180
Yeast
divalent inorganic cation transport GO:0072511 158 0.180
regulation of dendrite development GO:0050773 18 0.179
regulation of immune response GO:0050776 201 0.172
actin cytoskeleton organization GO:0030036 207 0.165
dephosphorylation GO:0016311 209 0.164
determination of adult lifespan GO:0008340 2 0.162
Fly
vasculature development GO:0001944 181 0.161
phosphatidylinositol mediated signaling GO:0048015 55 0.158
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.158
positive regulation of nucleoside metabolic process GO:0045979 186 0.156
Yeast
regulation of map kinase activity GO:0043405 108 0.155
calcium ion transmembrane transport GO:0070588 76 0.153
ameboidal type cell migration GO:0001667 135 0.151
cellular response to growth factor stimulus GO:0071363 197 0.151
positive regulation of organelle organization GO:0010638 195 0.150
Mouse
response to peptide hormone GO:0043434 61 0.147
Mouse
response to nitrogen compound GO:1901698 184 0.147
midbrain development GO:0030901 45 0.146
protein kinase b signaling GO:0043491 69 0.144
Rat
positive regulation of catabolic process GO:0009896 310 0.144
Yeast
cellular cation homeostasis GO:0030003 163 0.143
mitotic cell cycle GO:0000278 326 0.142
hematopoietic or lymphoid organ development GO:0048534 186 0.141
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.139
myeloid leukocyte migration GO:0097529 62 0.138
cellular calcium ion homeostasis GO:0006874 117 0.137
rac protein signal transduction GO:0016601 12 0.134
negative regulation of cardiac muscle cell apoptotic process GO:0010667 2 0.134
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.134
regulation of cell motility GO:2000145 299 0.133
protein modification by small protein conjugation GO:0032446 342 0.133
positive regulation of apoptotic signaling pathway GO:2001235 70 0.133
generation of neurons GO:0048699 152 0.131
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.130
Yeast
regulation of smooth muscle cell migration GO:0014910 15 0.129
response to cytokine GO:0034097 232 0.128
positive regulation of glial cell proliferation GO:0060252 2 0.126
cell morphogenesis GO:0000902 296 0.125
Fly
neutrophil migration GO:1990266 25 0.125
aging GO:0007568 66 0.125
Fly
tube development GO:0035295 125 0.125
oogenesis GO:0048477 2 0.124
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.124
multicellular organismal aging GO:0010259 3 0.123
Fly
regulation of ion transport GO:0043269 189 0.123
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.123
regulation of nervous system development GO:0051960 88 0.122
Mouse
regulation of cell cycle GO:0051726 393 0.121
Yeast
muscle system process GO:0003012 81 0.121
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.120
Yeast
regulation of metal ion transport GO:0010959 120 0.120
ion homeostasis GO:0050801 230 0.120
cellular ion homeostasis GO:0006873 168 0.119
positive regulation of cell death GO:0010942 263 0.118
cellular lipid catabolic process GO:0044242 65 0.118
Rat
insulin receptor signaling pathway GO:0008286 23 0.117
positive regulation of vasoconstriction GO:0045907 3 0.117
cellular response to amino acid stimulus GO:0071230 12 0.116
regeneration GO:0031099 4 0.115
phospholipid metabolic process GO:0006644 99 0.114
regulation of cell adhesion GO:0030155 166 0.114
negative regulation of intracellular signal transduction GO:1902532 183 0.113
positive regulation of cell adhesion GO:0045785 84 0.108
atrioventricular valve development GO:0003171 3 0.106
cellular divalent inorganic cation homeostasis GO:0072503 128 0.105
cellular chemical homeostasis GO:0055082 180 0.103
ribosome biogenesis GO:0042254 48 0.102
Yeast Fly
biological adhesion GO:0022610 331 0.102
positive regulation of protein ubiquitination GO:0031398 53 0.102
regulation of system process GO:0044057 101 0.099
peptidyl threonine phosphorylation GO:0018107 41 0.098
Mouse
inositol lipid mediated signaling GO:0048017 55 0.096
cellular response to organonitrogen compound GO:0071417 124 0.096
purine nucleoside monophosphate catabolic process GO:0009128 158 0.095
atp metabolic process GO:0046034 176 0.095
regulation of mapk cascade GO:0043408 262 0.093
cytokine mediated signaling pathway GO:0019221 109 0.093
muscle tissue development GO:0060537 62 0.093
regulation of endopeptidase activity GO:0052548 170 0.093
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.092
Fly
cardiac ventricle development GO:0003231 23 0.091
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.091
Yeast
memory GO:0007613 3 0.089
endothelial cell proliferation GO:0001935 65 0.089
Rat
negative regulation of glial cell apoptotic process GO:0034351 6 0.087
protein polymerization GO:0051258 71 0.087
Mouse
regulation of axon regeneration GO:0048679 1 0.086
positive regulation of cell differentiation GO:0045597 211 0.085
Mouse
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.085
regulation of protein binding GO:0043393 66 0.084
cellular response to peptide hormone stimulus GO:0071375 56 0.084
cellular response to dna damage stimulus GO:0006974 379 0.083
Yeast Fly
regulation of smooth muscle cell proliferation GO:0048660 28 0.083
cellular response to endogenous stimulus GO:0071495 336 0.082
leukocyte activation GO:0045321 164 0.082
organic acid transport GO:0015849 65 0.082
regulation of protein ubiquitination GO:0031396 95 0.081
ribonucleoside triphosphate metabolic process GO:0009199 412 0.080
Mouse
organic anion transport GO:0015711 103 0.080
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.078
chemical homeostasis GO:0048878 306 0.077
regulation of rac protein signal transduction GO:0035020 6 0.077
Mouse
peptidyl serine modification GO:0018209 106 0.077
sequestering of calcium ion GO:0051208 17 0.077
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.076
termination of signal transduction GO:0023021 3 0.076
system process GO:0003008 349 0.074
cellular response to cytokine stimulus GO:0071345 181 0.074
cognition GO:0050890 43 0.074
hemopoiesis GO:0030097 180 0.073
muscle contraction GO:0006936 73 0.073
modification dependent macromolecule catabolic process GO:0043632 212 0.072
neuron projection morphogenesis GO:0048812 50 0.072
Fly
developmental growth GO:0048589 48 0.071
Fly
mitral valve development GO:0003174 3 0.071
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.071
response to alkaloid GO:0043279 20 0.071
negative regulation of sequestering of calcium ion GO:0051283 41 0.070
positive regulation of gliogenesis GO:0014015 4 0.070
positive regulation of apoptotic process GO:0043065 246 0.069
cellular homeostasis GO:0019725 196 0.068
monosaccharide metabolic process GO:0005996 74 0.067
Rat
glucosylceramide catabolic process GO:0006680 2 0.067
cation transport GO:0006812 331 0.066
cellular response to organic cyclic compound GO:0071407 127 0.066
divalent metal ion transport GO:0070838 152 0.066
cell aging GO:0007569 52 0.066
protein maturation GO:0051604 233 0.066
protein catabolic process GO:0030163 325 0.065
positive regulation of endothelial cell migration GO:0010595 39 0.065
negative regulation of ion transmembrane transport GO:0034766 26 0.065
positive regulation of cell proliferation GO:0008284 301 0.065
Rat
positive regulation of translation GO:0045727 35 0.065
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.065
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.064
osteoblast differentiation GO:0001649 92 0.064
cellular metal ion homeostasis GO:0006875 146 0.063
positive regulation of ras gtpase activity GO:0032320 117 0.063
Yeast
regulation of protein catabolic process GO:0042176 155 0.062
response to glucagon GO:0033762 1 0.062
regulation of proteolysis GO:0030162 293 0.061
positive regulation of gtp catabolic process GO:0033126 166 0.061
Yeast
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.061
regulation of actin filament length GO:0030832 56 0.061
Mouse
head development GO:0060322 108 0.060
neural nucleus development GO:0048857 47 0.060
nervous system development GO:0007399 293 0.060
Mouse Fly
blood circulation GO:0008015 113 0.059
vesicle mediated transport GO:0016192 371 0.059
Yeast Fly
substantia nigra development GO:0021762 45 0.059
somatic stem cell maintenance GO:0035019 4 0.058
axonogenesis GO:0007409 31 0.058
Fly
regulation of fibroblast migration GO:0010762 7 0.058
regulation of dephosphorylation GO:0035303 96 0.057
organic acid catabolic process GO:0016054 71 0.057
Rat
positive regulation of nucleotide catabolic process GO:0030813 185 0.056
Yeast
basic amino acid transport GO:0015802 3 0.056
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.056
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.056
positive regulation of programmed cell death GO:0043068 249 0.055
cellular macromolecule catabolic process GO:0044265 380 0.055
rna interference GO:0016246 4 0.055
regulation of binding GO:0051098 111 0.053
regulation of ion transmembrane transport GO:0034765 132 0.053
skeletal muscle contraction GO:0003009 16 0.053
musculoskeletal movement GO:0050881 17 0.052
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.052
lymphocyte activation GO:0046649 133 0.052
response to alcohol GO:0097305 64 0.052
immune system development GO:0002520 195 0.051
activation of mapkk activity GO:0000186 18 0.051
cell substrate adhesion GO:0031589 132 0.051
brain development GO:0007420 97 0.051
response to redox state GO:0051775 7 0.051
cellular response to acid chemical GO:0071229 44 0.051
regulation of calcium ion transport GO:0051924 79 0.050
regulation of transcription from rna polymerase iii promoter GO:0006359 13 0.049
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.049
atp catabolic process GO:0006200 157 0.049
activin receptor signaling pathway GO:0032924 24 0.049
regulation of proteasomal protein catabolic process GO:0061136 87 0.049
negative regulation of developmental process GO:0051093 247 0.048
positive regulation of proteolysis GO:0045862 142 0.048
negative regulation of catabolic process GO:0009895 104 0.048
Yeast Mouse Fly
protein deubiquitination GO:0016579 79 0.048
regulation of protein polymerization GO:0032271 63 0.047
Mouse
regulation of macroautophagy GO:0016241 19 0.047
Mouse Fly
cellular protein catabolic process GO:0044257 261 0.047
enzyme linked receptor protein signaling pathway GO:0007167 303 0.047
regulation of endothelial cell proliferation GO:0001936 56 0.046
Rat
cellular lipid metabolic process GO:0044255 303 0.046
Yeast Rat
positive regulation of cell development GO:0010720 92 0.046
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.045
sequestering of metal ion GO:0051238 24 0.045
positive regulation of oxidoreductase activity GO:0051353 26 0.045
trabecula morphogenesis GO:0061383 2 0.044
long term synaptic potentiation GO:0060291 1 0.044
negative regulation of cell proliferation GO:0008285 228 0.044
single organism membrane organization GO:0044802 268 0.043
oxidation reduction process GO:0055114 396 0.042
Rat
ribonucleoside monophosphate catabolic process GO:0009158 158 0.042
positive regulation of protein binding GO:0032092 24 0.042
cellular glucan metabolic process GO:0006073 22 0.042
Rat
positive regulation of cellular component movement GO:0051272 181 0.042
negative regulation of protein dephosphorylation GO:0035308 3 0.042
nucleoside monophosphate metabolic process GO:0009123 191 0.042
regulation of heart contraction GO:0008016 50 0.042
regulation of calcium ion transmembrane transport GO:1903169 28 0.041
spongiotrophoblast layer development GO:0060712 1 0.041
regulation of nuclear division GO:0051783 65 0.041
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.041
negative regulation of cellular amine metabolic process GO:0033239 3 0.041
ubiquitin dependent protein catabolic process GO:0006511 206 0.040
peptidyl tyrosine modification GO:0018212 170 0.040
Mouse
synapse organization GO:0050808 14 0.040
Fly
regulation of synaptic plasticity GO:0048167 3 0.040
positive regulation of superoxide anion generation GO:0032930 4 0.040
regulation of protein kinase b signaling GO:0051896 61 0.040
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.039
divalent inorganic cation homeostasis GO:0072507 136 0.039
cardiac muscle cell fate commitment GO:0060923 4 0.039
regulation of cysteine type endopeptidase activity GO:2000116 127 0.039
regulation of cell migration GO:0030334 289 0.039
hexose metabolic process GO:0019318 55 0.039
Rat
neural tube formation GO:0001841 3 0.039
response to caffeine GO:0031000 3 0.039
regulation of response to external stimulus GO:0032101 222 0.038
Mouse Rat Fly
positive regulation of immune response GO:0050778 159 0.038
anatomical structure homeostasis GO:0060249 100 0.038
cardiac ventricle morphogenesis GO:0003208 20 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
regulation of protein localization GO:0032880 296 0.038
Mouse
response to light stimulus GO:0009416 87 0.037
Fly
sister chromatid segregation GO:0000819 54 0.037
cytosolic calcium ion homeostasis GO:0051480 89 0.037
regulation of fatty acid beta oxidation GO:0031998 8 0.037
Rat
positive regulation of endopeptidase activity GO:0010950 84 0.036
rna catabolic process GO:0006401 71 0.036
regulation of cell projection organization GO:0031344 107 0.035
Mouse
lipid oxidation GO:0034440 33 0.035
Rat
regulation of anion transport GO:0044070 25 0.035
regulation of phospholipid scramblase activity GO:1900161 1 0.035
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.035
epithelial tube morphogenesis GO:0060562 38 0.035
cellular response to hormone stimulus GO:0032870 125 0.034
ribonucleoside monophosphate metabolic process GO:0009161 187 0.034
female gamete generation GO:0007292 2 0.034
regulation of blood circulation GO:1903522 59 0.034
metal ion transport GO:0030001 272 0.034
posttranscriptional regulation of gene expression GO:0010608 213 0.034
erk1 and erk2 cascade GO:0070371 104 0.034
negative regulation of transmembrane transport GO:0034763 29 0.034
cell projection organization GO:0030030 252 0.034
Mouse Rat Fly
negative regulation of lipid catabolic process GO:0050995 9 0.034
endocardium development GO:0003157 2 0.033
sphingolipid metabolic process GO:0006665 38 0.033
Yeast
skeletal muscle tissue growth GO:0048630 2 0.033
regulation of endothelial cell migration GO:0010594 67 0.033
ion transmembrane transport GO:0034220 338 0.033
modification dependent protein catabolic process GO:0019941 209 0.033
epithelial to mesenchymal transition GO:0001837 48 0.033
positive regulation of substrate adhesion dependent cell spreading GO:1900026 15 0.033
positive regulation of cell growth GO:0030307 48 0.033
hindbrain development GO:0030902 3 0.033
hexose transport GO:0008645 30 0.033
negative regulation of mapk cascade GO:0043409 56 0.032
positive regulation of developmental process GO:0051094 314 0.032
Mouse
nucleoside monophosphate catabolic process GO:0009125 159 0.032
endoplasmic reticulum to cytosol transport GO:1903513 13 0.031
lipid biosynthetic process GO:0008610 177 0.031
regulation of cation channel activity GO:2001257 33 0.031
response to axon injury GO:0048678 1 0.031
positive regulation of gtpase activity GO:0043547 166 0.031
Yeast
hair cycle GO:0042633 28 0.031
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.031
atrial septum primum morphogenesis GO:0003289 1 0.030
transmembrane transport GO:0055085 399 0.030
striated muscle cell apoptotic process GO:0010658 3 0.030
positive regulation of mapk cascade GO:0043410 190 0.030
positive regulation of cellular protein catabolic process GO:1903364 37 0.030
ribonucleoprotein complex biogenesis GO:0022613 116 0.029
Yeast Fly
regulation of myeloid cell differentiation GO:0045637 81 0.029
leukocyte migration GO:0050900 107 0.029
dna repair GO:0006281 198 0.029
cardiac chamber morphogenesis GO:0003206 26 0.029
fatty acid catabolic process GO:0009062 29 0.029
Rat
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.029
ribonucleoprotein complex assembly GO:0022618 78 0.029
dendrite development GO:0016358 24 0.029
Fly
nuclear transcribed mrna catabolic process GO:0000956 48 0.029
cellular response to abiotic stimulus GO:0071214 117 0.029
glycerolipid metabolic process GO:0046486 107 0.029
organelle assembly GO:0070925 176 0.029

MTOR disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.086
muscular disease DOID:0080000 114 0.050
muscle tissue disease DOID:66 113 0.050
cancer DOID:162 167 0.041
disease of cellular proliferation DOID:14566 174 0.041
organ system cancer DOID:0050686 164 0.041
myopathy DOID:423 104 0.040
central nervous system disease DOID:331 186 0.032
neurodegenerative disease DOID:1289 102 0.032
nervous system disease DOID:863 431 0.032