|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
1.000
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
1.000
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.999
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.996
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.996
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.992
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.992
|
|
|
|
atp dependent chromatin remodeling
|
GO:0043044 |
25 |
0.991
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.990
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.989
|
Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.988
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.986
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.984
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.981
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.979
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.978
|
Mouse |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.976
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.975
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.974
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.971
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.968
|
Rat |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.964
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.962
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.959
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.951
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.948
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.947
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.946
|
Mouse Rat Worm |
|
|
histone modification
|
GO:0016570 |
251 |
0.941
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.940
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.938
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.927
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.926
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.924
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.917
|
Rat |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.907
|
Mouse |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.907
|
Mouse |
|
|
dna repair
|
GO:0006281 |
198 |
0.900
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.898
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.890
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.886
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.884
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.874
|
Rat |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.874
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.872
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.871
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.871
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.858
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.856
|
Mouse Rat |
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.846
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.844
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.840
|
Mouse |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.838
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.831
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.828
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.822
|
Mouse |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.820
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.816
|
Mouse |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.815
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.813
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.810
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.805
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.798
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.795
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.793
|
Rat |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.789
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.789
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.780
|
Rat |
|
|
taxis
|
GO:0042330 |
157 |
0.779
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.774
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.769
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.768
|
Rat |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.767
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.765
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.748
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.728
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.727
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.716
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.705
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.704
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.704
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.700
|
Mouse |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.694
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.692
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.691
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.689
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.689
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.679
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.674
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.671
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.670
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.665
|
Rat |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.643
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.637
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.635
|
Rat |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.635
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.634
|
Mouse |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.629
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.608
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.573
|
Rat |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.568
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.566
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.563
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.561
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.549
|
|
|
|
aging
|
GO:0007568 |
66 |
0.543
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.537
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.535
|
Rat |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.532
|
Rat |
|
|
lipid localization
|
GO:0010876 |
106 |
0.527
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.513
|
Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.510
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.506
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.489
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.487
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.480
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.479
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.473
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.473
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.471
|
Rat |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.461
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.451
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.445
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.441
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.438
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.436
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.434
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.433
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.430
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.426
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.424
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.422
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.421
|
|
|
|
histone exchange
|
GO:0043486 |
3 |
0.405
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.395
|
Rat Worm |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.382
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.378
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.375
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.375
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.372
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.365
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.365
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.361
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.361
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.360
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.354
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.353
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.353
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.349
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.347
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.343
|
Mouse |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.340
|
Rat |
|
|
eye development
|
GO:0001654 |
42 |
0.336
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.330
|
Rat |
|
|
rna processing
|
GO:0006396 |
255 |
0.329
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.325
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.322
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.321
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.316
|
Mouse |
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.315
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.311
|
Mouse |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.309
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.307
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.304
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.302
|
Rat |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.301
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.296
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.295
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.290
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.287
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.285
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.284
|
Mouse |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.280
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.277
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.274
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.270
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.269
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.266
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.266
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.265
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.258
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.254
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.253
|
|
|
|
growth
|
GO:0040007 |
202 |
0.252
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.249
|
Rat |
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.247
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.246
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.245
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.244
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.244
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.243
|
Rat |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.241
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.241
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.240
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.240
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.239
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.238
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.234
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.233
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.233
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.231
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.231
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.229
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.229
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.228
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.228
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.226
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.225
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.223
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.220
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.219
|
Rat |
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.219
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.215
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.210
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.208
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.205
|
Rat |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.203
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.202
|
Mouse |
|
|
oogenesis
|
GO:0048477 |
2 |
0.199
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.197
|
Rat |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.194
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.191
|
Mouse |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.189
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.188
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.183
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.182
|
Rat |
|
|
camera type eye development
|
GO:0043010 |
25 |
0.179
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.178
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.178
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.176
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.176
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.173
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.173
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.172
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.172
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.171
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.171
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.170
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.170
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.168
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.168
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.167
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.167
|
|
|
|
nucleosome organization
|
GO:0034728 |
66 |
0.165
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.161
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.158
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.157
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.157
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.156
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.154
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.152
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.152
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.150
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.149
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.149
|
Rat |
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
9 |
0.148
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.145
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.141
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.141
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.141
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.140
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.138
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.137
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.136
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.135
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.134
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.133
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.132
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.132
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.129
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.129
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.128
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
23 |
0.126
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.125
|
Mouse |
|
|
cell aging
|
GO:0007569 |
52 |
0.124
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.124
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.123
|
Mouse |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.123
|
Rat |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.120
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.119
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.119
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.116
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.115
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.115
|
|
|
|
rrna modification
|
GO:0000154 |
2 |
0.114
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.114
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.113
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.112
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.111
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.109
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.109
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.109
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.106
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.106
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.105
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.103
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.103
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.102
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.102
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.102
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.101
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.101
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.100
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.100
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.099
|
|
|
|
histone h2a acetylation
|
GO:0043968 |
12 |
0.098
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.095
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.092
|
Rat |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.091
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.091
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.090
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.090
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.089
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.089
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.089
|
Rat |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.088
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.086
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.085
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.085
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.085
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.084
|
Rat |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.083
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.083
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.082
|
|
|
|
neural retina development
|
GO:0003407 |
8 |
0.081
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.081
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.081
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.081
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.080
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.080
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.080
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.079
|
Rat |
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.078
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.078
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.077
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.077
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.077
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.076
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.076
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.076
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.075
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.073
|
Rat |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.073
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.072
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.072
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.072
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
62 |
0.071
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.071
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.070
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.070
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.069
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.069
|
Mouse |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.069
|
|
|
|
in utero embryonic development
|
GO:0001701 |
8 |
0.069
|
Rat |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.069
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.069
|
Rat |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.068
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.066
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
25 |
0.066
|
|
|
|
sperm egg recognition
|
GO:0035036 |
3 |
0.065
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.065
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.065
|
Mouse |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.064
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.064
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.064
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.063
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.063
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.063
|
Rat |
|
|
mismatch repair
|
GO:0006298 |
15 |
0.062
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.061
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.061
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.061
|
|
|
|
heart induction
|
GO:0003129 |
4 |
0.061
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.060
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.059
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.059
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.058
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.058
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.058
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.058
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.058
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.057
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.056
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.056
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.056
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.056
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.056
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.055
|
Rat |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.055
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.055
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.054
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.054
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.054
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.053
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.053
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.053
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.053
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.052
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.052
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.051
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.051
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.051
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.051
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.051
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.051
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.051
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.050
|
Rat |
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.049
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.049
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.049
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.049
|
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.049
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.049
|
|
|
|
regulation of rna stability
|
GO:0043487 |
23 |
0.049
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.049
|
Mouse |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.048
|
|
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.047
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.047
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.047
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.047
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.046
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.046
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.046
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.046
|
|
|
|
toxin transport
|
GO:1901998 |
4 |
0.046
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.045
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.045
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.045
|
Mouse |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.045
|
Rat |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.045
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.044
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.044
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.043
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.043
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.041
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.041
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.041
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.041
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.041
|
Mouse |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.040
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.040
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.040
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.039
|
|
|
|
small nucleolar ribonucleoprotein complex assembly
|
GO:0000491 |
3 |
0.039
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.039
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.039
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.038
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.038
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.038
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.038
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.037
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.037
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.037
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.037
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.037
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.037
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.037
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.036
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.036
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.035
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.035
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.034
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.034
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.034
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.034
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.034
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.034
|
Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.033
|
Rat |
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.033
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.032
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.032
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.032
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.032
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.032
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.032
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.032
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.031
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.031
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.031
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.031
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.031
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.031
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.030
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.030
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.030
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.030
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.030
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.030
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.030
|
|
