|
|
actin filament based process
|
GO:0030029 |
224 |
1.000
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
1.000
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.999
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.995
|
Human Worm Fly |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.992
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.988
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.985
|
Human Mouse Worm Fly |
|
|
ventricular cardiac muscle tissue morphogenesis
|
GO:0055010 |
14 |
0.982
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.980
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.979
|
Fly |
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.976
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.975
|
Fly |
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.963
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.961
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.959
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.958
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.957
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
22 |
0.957
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.935
|
Human |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.922
|
Worm Fly |
|
|
cell development
|
GO:0048468 |
328 |
0.921
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.911
|
|
|
|
sarcomere organization
|
GO:0045214 |
8 |
0.902
|
Fly |
|
|
muscle contraction
|
GO:0006936 |
73 |
0.902
|
Human Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.895
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.889
|
Fly |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.887
|
Worm Fly |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.884
|
|
|
|
regulation of actin filament depolymerization
|
GO:0030834 |
10 |
0.883
|
|
|
|
skeletal muscle thin filament assembly
|
GO:0030240 |
3 |
0.878
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.868
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.867
|
Worm Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.850
|
Worm Fly |
|
|
muscle system process
|
GO:0003012 |
81 |
0.848
|
Human Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.838
|
Fly |
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
0.837
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.826
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.825
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.818
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.814
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.810
|
Human Worm Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.806
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.802
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.795
|
Rat |
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.792
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.784
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.782
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.777
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.775
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.773
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.772
|
Human Worm Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.752
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.738
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.728
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.725
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.721
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.720
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.717
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.716
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.709
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.706
|
Human |
|
|
coagulation
|
GO:0050817 |
78 |
0.704
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.702
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.702
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.699
|
Fly |
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.696
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.689
|
Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.686
|
|
|
|
ventricular cardiac muscle tissue development
|
GO:0003229 |
14 |
0.678
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.678
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.676
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.661
|
Human Mouse Worm Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.659
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.656
|
Human |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.651
|
Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.649
|
Worm Fly |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.645
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.643
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.639
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.637
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.632
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.617
|
Human Worm Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.602
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.597
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.594
|
Human Worm Fly |
|
|
protein targeting
|
GO:0006605 |
187 |
0.583
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.581
|
Human Worm Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.579
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.572
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.569
|
Mouse |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.547
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.538
|
Human Mouse Worm Fly |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.537
|
Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.535
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.533
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.531
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.522
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.520
|
Mouse Worm Fly |
|
|
protein import
|
GO:0017038 |
130 |
0.516
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.510
|
Rat |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.509
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.501
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.496
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.490
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.489
|
Worm Fly |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.488
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.480
|
|
|
|
negative regulation of actin filament depolymerization
|
GO:0030835 |
5 |
0.471
|
|
|
|
actin crosslink formation
|
GO:0051764 |
1 |
0.470
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.457
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.451
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.449
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.445
|
Mouse Worm Fly |
|
|
system process
|
GO:0003008 |
349 |
0.442
|
Human Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.440
|
|
|
|
protein depolymerization
|
GO:0051261 |
30 |
0.436
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.430
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.423
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.421
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.413
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.412
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.410
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.410
|
Mouse |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.408
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.402
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.401
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.398
|
Rat |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.396
|
Rat |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.395
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.387
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.385
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.379
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.379
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
18 |
0.374
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.372
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.368
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
20 |
0.365
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.363
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.362
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.358
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.344
|
Rat |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.334
|
|
|
|
mating
|
GO:0007618 |
1 |
0.332
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.332
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.332
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.329
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.328
|
|
|
|
growth
|
GO:0040007 |
202 |
0.316
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.315
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.312
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.311
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.310
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.310
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.308
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.306
|
Rat |
|
|
nuclear import
|
GO:0051170 |
106 |
0.303
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.299
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.299
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.295
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.291
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.287
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.286
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.285
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.283
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.283
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.282
|
Rat |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.281
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.278
|
Rat |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.276
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.276
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.275
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.274
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.274
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.273
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.257
|
|
|
|
uterus morphogenesis
|
GO:0061038 |
2 |
0.257
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.252
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.251
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.248
|
|
|
|
negative regulation of actin filament polymerization
|
GO:0030837 |
10 |
0.243
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.240
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.240
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
20 |
0.238
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.238
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.235
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.235
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.235
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.233
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.231
|
|
|
|
adenylate cyclase inhibiting dopamine receptor signaling pathway
|
GO:0007195 |
4 |
0.230
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.229
|
Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.226
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.223
|
Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.220
|
Fly |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.216
|
|
|
|
protein o linked glycosylation via serine
|
GO:0018242 |
3 |
0.215
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.215
|
|
|
|
actin filament capping
|
GO:0051693 |
4 |
0.215
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.215
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.210
|
Rat Worm |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.209
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.208
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.207
|
Rat |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.206
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.204
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.203
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.202
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.200
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.200
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.199
|
Worm Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.195
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.191
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.188
|
Worm Fly |
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.184
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.184
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.183
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.182
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.181
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.176
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.176
|
|
|
|
adult behavior
|
GO:0030534 |
18 |
0.174
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.174
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.174
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.170
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.169
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
19 |
0.165
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.161
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.160
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.160
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.160
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.158
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.158
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.156
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.155
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.154
|
|
|
|
skeletal myofibril assembly
|
GO:0014866 |
3 |
0.154
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.153
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.152
|
|
|
|
positive regulation of potassium ion transport
|
GO:0043268 |
15 |
0.151
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.151
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.150
|
Fly |
|
|
taxis
|
GO:0042330 |
157 |
0.149
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.149
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.149
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.146
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.144
|
Worm Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.143
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.143
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.141
|
|
|
|
regulation of cardiac muscle cell membrane potential
|
GO:0086036 |
1 |
0.140
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.140
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.138
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.136
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.135
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.133
|
|
|
|
myofibril assembly
|
GO:0030239 |
10 |
0.132
|
Worm Fly |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.131
|
Human |
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.130
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.130
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.130
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.128
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.128
|
Mouse |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.127
|
|
|
|
memory
|
GO:0007613 |
3 |
0.126
|
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.125
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.124
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.124
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.123
|
Worm |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.122
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.121
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.121
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.120
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.119
|
Fly |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.119
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.118
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
22 |
0.118
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.117
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.117
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.117
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.117
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.116
|
Rat Worm |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.116
|
Rat |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.116
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.116
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.116
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.115
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.114
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.113
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.112
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.111
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.111
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.111
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.108
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.106
|
Fly |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.105
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.102
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.099
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.098
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.097
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.097
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.097
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.096
|
Mouse |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.095
|
Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.095
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.095
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.094
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.094
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.094
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.093
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.093
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.093
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.089
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.089
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.088
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.088
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.088
|
Fly |
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.087
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.087
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.086
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.086
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.085
|
Mouse |
|
|
molting cycle
|
GO:0042303 |
28 |
0.084
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.079
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.079
|
Worm Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.078
|
|
|
|
tube formation
|
GO:0035148 |
10 |
0.078
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.077
|
|
|
|
actin filament depolymerization
|
GO:0030042 |
12 |
0.076
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.075
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.074
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.074
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.073
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.073
|
Fly |
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.073
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.072
|
|
|
|
protein localization to cell surface
|
GO:0034394 |
28 |
0.072
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.071
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.070
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.069
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.069
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.069
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.068
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.068
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.068
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.068
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.068
|
Worm Fly |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.068
|
|
|
|
barbed end actin filament capping
|
GO:0051016 |
3 |
0.067
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.067
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.066
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.066
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.066
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.065
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.064
|
|
|
|
negative regulation of potassium ion transmembrane transport
|
GO:1901380 |
5 |
0.063
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.062
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.062
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.062
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.062
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.061
|
Rat |
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.061
|
Worm |
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.061
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
17 |
0.061
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.061
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.061
|
Worm Fly |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.061
|
Fly |
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.060
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.060
|
Mouse |
|
|
chronological cell aging
|
GO:0001300 |
2 |
0.060
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.059
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.058
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.057
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.057
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.056
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.056
|
|
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.056
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.056
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.056
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.055
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.055
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.054
|
Fly |
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.054
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.053
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.053
|
Worm |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.053
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.052
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.052
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.052
|
Rat |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.051
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.051
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.051
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.051
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.051
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.050
|
Rat |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.050
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.050
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.050
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.050
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.049
|
Human |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.049
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.048
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.048
|
Worm Fly |
|
|
axonogenesis
|
GO:0007409 |
31 |
0.048
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.048
|
|
|
|
positive regulation of potassium ion transmembrane transport
|
GO:1901381 |
12 |
0.048
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.047
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.047
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.047
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.047
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.047
|
|
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
22 |
0.046
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.046
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.046
|
Mouse Worm Fly |
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.045
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
8 |
0.045
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.045
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.045
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.044
|
Rat |
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.044
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.044
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.044
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.044
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.043
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.043
|
Worm |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.043
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.043
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.043
|
Rat |
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.042
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.042
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.042
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.042
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.042
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.041
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
29 |
0.041
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.041
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.041
|
Rat |
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.041
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.041
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.040
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.040
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.040
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.040
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.040
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.040
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.039
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.039
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.039
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.039
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.038
|
|
|
|
positive regulation of potassium ion transmembrane transporter activity
|
GO:1901018 |
8 |
0.038
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.038
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.038
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.038
|
|
|
|
integrin activation
|
GO:0033622 |
8 |
0.038
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.038
|
|
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.038
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.037
|
Mouse |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.037
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.037
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.037
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.037
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.037
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.037
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.036
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.036
|
Fly |
|
|
spermatid development
|
GO:0007286 |
4 |
0.036
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.036
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.036
|
|
|
|
positive regulation of transporter activity
|
GO:0032411 |
32 |
0.036
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.036
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.035
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.035
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.035
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.035
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.035
|
|