|
|
double strand break repair
|
GO:0006302 |
101 |
1.000
|
|
|
|
dna double strand break processing
|
GO:0000729 |
10 |
0.999
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.999
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.998
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.998
|
|
|
|
telomere maintenance via telomere lengthening
|
GO:0010833 |
9 |
0.994
|
|
|
|
telomere capping
|
GO:0016233 |
5 |
0.994
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.993
|
|
|
|
positive regulation of protein autophosphorylation
|
GO:0031954 |
9 |
0.990
|
|
|
|
dna catabolic process exonucleolytic
|
GO:0000738 |
17 |
0.986
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.973
|
Mouse |
|
|
double strand break repair via single strand annealing
|
GO:0045002 |
4 |
0.972
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.970
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.967
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.967
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.963
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.963
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.959
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
15 |
0.957
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.957
|
|
|
|
telomere maintenance
|
GO:0000723 |
32 |
0.954
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.951
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.946
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.938
|
|
|
|
dna damage induced protein phosphorylation
|
GO:0006975 |
5 |
0.937
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
31 |
0.935
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.934
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.928
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.926
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.913
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.905
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.904
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.896
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.892
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.891
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.885
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.861
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.858
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.855
|
|
|
|
nucleosome assembly
|
GO:0006334 |
50 |
0.855
|
|
|
|
dna geometric change
|
GO:0032392 |
32 |
0.854
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.848
|
|
|
|
telomere organization
|
GO:0032200 |
33 |
0.836
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.831
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.820
|
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.819
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.814
|
|
|
|
dna duplex unwinding
|
GO:0032508 |
30 |
0.814
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.811
|
Mouse |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.789
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.772
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.763
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.729
|
|
|
|
replication fork processing
|
GO:0031297 |
13 |
0.722
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.715
|
|
|
|
regulation of transcription by chromatin organization
|
GO:0034401 |
1 |
0.715
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.697
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.682
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.681
|
|
|
|
positive regulation of telomere maintenance
|
GO:0032206 |
4 |
0.675
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.605
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.602
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.584
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.580
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
3 |
0.573
|
Mouse |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.569
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.565
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.558
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.541
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.540
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.514
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.513
|
|
|
|
non recombinational repair
|
GO:0000726 |
14 |
0.508
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.503
|
Mouse |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.502
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.499
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.497
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.488
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.472
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.471
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.466
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.462
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.456
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.455
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.445
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.440
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.439
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.432
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.430
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.426
|
|
|
|
telomere maintenance via telomerase
|
GO:0007004 |
8 |
0.413
|
|
|
|
double strand break repair via nonhomologous end joining
|
GO:0006303 |
10 |
0.410
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
19 |
0.405
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.403
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.399
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.391
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.387
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.383
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.375
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.375
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.374
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.369
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.362
|
|
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.352
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.349
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.348
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.338
|
|
|
|
positive regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043517 |
8 |
0.329
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.324
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.322
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.320
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.315
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.314
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.312
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.310
|
|
|
|
telomere maintenance via recombination
|
GO:0000722 |
4 |
0.309
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.308
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.307
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.307
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.302
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.300
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.288
|
Mouse |
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.288
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.284
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.282
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.281
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.279
|
|
|
|
reciprocal dna recombination
|
GO:0035825 |
4 |
0.279
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.276
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.275
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.275
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.275
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.268
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.268
|
|
|
|
rna dependent dna replication
|
GO:0006278 |
16 |
0.266
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.263
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.263
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.261
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.261
|
Mouse |
|
|
regulation of dna endoreduplication
|
GO:0032875 |
5 |
0.255
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.251
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.249
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.248
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.247
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.246
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.246
|
|
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
7 |
0.240
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.238
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.236
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.235
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
4 |
0.235
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.232
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.228
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.222
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.219
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.216
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.214
|
|
|
|
histone h4 k20 methylation
|
GO:0034770 |
1 |
0.211
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.209
|
|
|
|
isotype switching
|
GO:0045190 |
3 |
0.204
|
Mouse |
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.201
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.201
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.198
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.197
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.196
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.196
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.193
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.188
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.186
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.184
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.184
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.182
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.181
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.176
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.168
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.167
|
|
|
|
reciprocal meiotic recombination
|
GO:0007131 |
4 |
0.163
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.160
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.159
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.159
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.159
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.157
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.154
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.153
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.149
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
8 |
0.148
|
|
|
|
regulation of telomere maintenance
|
GO:0032204 |
13 |
0.146
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.145
|
|
|
|
regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043516 |
20 |
0.143
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.143
|
|
|
|
mitotic recombination
|
GO:0006312 |
8 |
0.142
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.141
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.141
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.137
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.135
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.135
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.135
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.132
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.132
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.130
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.130
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.130
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.128
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.127
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.125
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.125
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.124
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.120
|
|
|
|
dna replication independent nucleosome organization
|
GO:0034724 |
27 |
0.116
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.115
|
|
|
|
positive regulation of signal transduction by p53 class mediator
|
GO:1901798 |
10 |
0.111
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.110
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.109
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.109
|
|
|
|
regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034243 |
13 |
0.107
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.107
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.105
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.105
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.103
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.100
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.097
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.097
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.096
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.096
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.095
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.094
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.094
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.092
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.091
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.091
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.091
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.089
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.089
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.089
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.089
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.088
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.085
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.084
|
|
|
|
negative regulation of dna dependent dna replication
|
GO:2000104 |
9 |
0.084
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.083
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.081
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.079
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.079
|
|
|
|
dna synthesis involved in dna repair
|
GO:0000731 |
6 |
0.079
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.079
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.079
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.077
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.077
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.076
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.076
|
|
|
|
histone h4 k16 acetylation
|
GO:0043984 |
14 |
0.076
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
3 |
0.075
|
Mouse |
|
|
negative regulation of telomerase activity
|
GO:0051974 |
6 |
0.074
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.073
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.073
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.072
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.071
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.070
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.070
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.069
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.069
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.068
|
|
|
|
positive regulation vascular endothelial growth factor production
|
GO:0010575 |
12 |
0.067
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.067
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.066
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.066
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.065
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.065
|
|
|
|
single strand break repair
|
GO:0000012 |
6 |
0.065
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.064
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
27 |
0.063
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.062
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.062
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.060
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.060
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.059
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.059
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.058
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.058
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.057
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.057
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.057
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.057
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.057
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.057
|
|
|
|
positive regulation of camp dependent protein kinase activity
|
GO:2000481 |
4 |
0.057
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.056
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.056
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.056
|
|
|
|
histone h2a phosphorylation
|
GO:1990164 |
3 |
0.055
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.055
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.055
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.055
|
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.054
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.054
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.054
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.053
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.053
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.053
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.053
|
|
|
|
negative regulation of dna endoreduplication
|
GO:0032876 |
5 |
0.053
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.052
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
37 |
0.051
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.050
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
8 |
0.049
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.048
|
Mouse |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.048
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.048
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.047
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.047
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.047
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.047
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
247 |
0.047
|
|
|
|
positive regulation of mhc class ii biosynthetic process
|
GO:0045348 |
3 |
0.046
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.046
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.046
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.046
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.044
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.044
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.043
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
5 |
0.043
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.043
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.042
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.042
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.042
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.042
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.041
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.041
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
23 |
0.041
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.041
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.040
|
|
|
|
protein localization to chromosome telomeric region
|
GO:0070198 |
6 |
0.040
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.039
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.039
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.039
|
|
|
|
histone phosphorylation
|
GO:0016572 |
16 |
0.039
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.039
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.038
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.038
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.038
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.038
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.038
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.037
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.036
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.036
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.035
|
|
|
|
v d j recombination
|
GO:0033151 |
3 |
0.035
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.035
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.035
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.035
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.035
|
|
|
|
aging
|
GO:0007568 |
66 |
0.035
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.034
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.034
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.034
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.034
|
|
|
|
regulation of sister chromatid cohesion
|
GO:0007063 |
9 |
0.033
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.033
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.033
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.033
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.032
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.032
|
|
|
|
dna replication independent nucleosome assembly
|
GO:0006336 |
27 |
0.032
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.031
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.031
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.031
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.031
|
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
5 |
0.031
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.031
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.030
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.030
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.030
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.030
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.030
|
Mouse |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.030
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.030
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.030
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.029
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.029
|
|
|
|
n terminal peptidyl lysine acetylation
|
GO:0018076 |
4 |
0.029
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.028
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.028
|
|
|
|
positive regulation of dna repair
|
GO:0045739 |
25 |
0.028
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.028
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.028
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.028
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.028
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.027
|
|
|
|
system process
|
GO:0003008 |
349 |
0.027
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.027
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.027
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.027
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.026
|
|
|
|
prostanoid metabolic process
|
GO:0006692 |
17 |
0.026
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.026
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.026
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.026
|
|
|
|
phosphatidylinositol 3 phosphate biosynthetic process
|
GO:0036092 |
3 |
0.026
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.025
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.025
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.025
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.025
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.025
|
|
|
|
histone h2a k63 linked ubiquitination
|
GO:0070535 |
5 |
0.025
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.025
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.025
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
10 |
0.024
|
|
|
|
histone mrna catabolic process
|
GO:0071044 |
10 |
0.024
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.024
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.024
|
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.024
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.024
|
Mouse |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.024
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.024
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.024
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.024
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.024
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.024
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.024
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.024
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.024
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.024
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.024
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.024
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.023
|
|
|
|
negative regulation of fatty acid metabolic process
|
GO:0045922 |
8 |
0.023
|
|
|
|
negative regulation of histone h3 k9 methylation
|
GO:0051573 |
3 |
0.023
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.023
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.023
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.023
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.022
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.022
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.022
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.022
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.022
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.022
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.022
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.022
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.022
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.022
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.022
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.021
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.021
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.021
|
|
|
|
dna dependent dna replication maintenance of fidelity
|
GO:0045005 |
14 |
0.021
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.021
|
|
|
|
positive regulation of histone methylation
|
GO:0031062 |
12 |
0.021
|
|
|
|
regulation of telomere maintenance via telomerase
|
GO:0032210 |
6 |
0.021
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.021
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.021
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.021
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.021
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.021
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.021
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.021
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.020
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.020
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.020
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.020
|
|
|
|
response to glucagon
|
GO:0033762 |
1 |
0.020
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.020
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.020
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.019
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.019
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.019
|
|
|
|
negative regulation of sister chromatid segregation
|
GO:0033046 |
17 |
0.019
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.019
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.019
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.019
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.019
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.019
|
|
|
|
multicellular organism growth
|
GO:0035264 |
8 |
0.019
|
|
|
|
mismatch repair
|
GO:0006298 |
15 |
0.019
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.019
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.019
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.019
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.019
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.019
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.019
|
Mouse |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.018
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.018
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.018
|
|
|
|
unsaturated fatty acid biosynthetic process
|
GO:0006636 |
21 |
0.018
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.018
|
|
|
|
mitotic spindle assembly checkpoint
|
GO:0007094 |
14 |
0.018
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.018
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.018
|
|
|
|
regulation of dna templated transcription initiation
|
GO:2000142 |
9 |
0.018
|
|
