|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.982
|
|
|
|
positive regulation of glucocorticoid receptor signaling pathway
|
GO:2000324 |
1 |
0.978
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.977
|
|
|
|
regulation of intracellular estrogen receptor signaling pathway
|
GO:0033146 |
13 |
0.975
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.967
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.966
|
|
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.963
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.957
|
|
|
|
intracellular estrogen receptor signaling pathway
|
GO:0030520 |
23 |
0.956
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.947
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.939
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.929
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.927
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.915
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.909
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.902
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.897
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.893
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.887
|
|
|
|
carbon catabolite regulation of transcription from rna polymerase ii promoter
|
GO:0000429 |
3 |
0.886
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.874
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.867
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.862
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.858
|
|
|
|
positive regulation of intracellular estrogen receptor signaling pathway
|
GO:0033148 |
5 |
0.844
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.841
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.816
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.804
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.802
|
Mouse |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.795
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.788
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.779
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.757
|
|
|
|
carbon catabolite activation of transcription from rna polymerase ii promoter
|
GO:0000436 |
3 |
0.751
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.745
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.736
|
|
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.732
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.731
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
3 |
0.731
|
Human |
|
|
hormone mediated signaling pathway
|
GO:0009755 |
22 |
0.727
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.714
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.712
|
Mouse |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.703
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.701
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.698
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.663
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.656
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.654
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.635
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.616
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.604
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.597
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.587
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.577
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.567
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.557
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.533
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.526
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.525
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.522
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.492
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.490
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.490
|
|
|
|
regulation of transcription from rna polymerase ii promoter by galactose
|
GO:0000431 |
1 |
0.483
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.480
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.479
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.474
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.471
|
|
|
|
regulation of transcription involved in lymphatic endothelial cell fate commitment
|
GO:0060849 |
2 |
0.466
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.461
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.460
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.433
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.429
|
|
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
3 |
0.426
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.412
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.406
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.394
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.391
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.388
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.385
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.380
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.379
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.377
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.374
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.366
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.366
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.359
|
|
|
|
male gonad development
|
GO:0008584 |
23 |
0.357
|
|
|
|
positive regulation of epidermis development
|
GO:0045684 |
11 |
0.354
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.348
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.347
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.346
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.346
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.343
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.340
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.339
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.337
|
Mouse |
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.334
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.333
|
|
|
|
response to osmotic stress
|
GO:0006970 |
17 |
0.331
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.327
|
|
|
|
regulation of myelination
|
GO:0031641 |
1 |
0.326
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.323
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.315
|
|
|
|
mrna catabolic process
|
GO:0006402 |
56 |
0.307
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.305
|
|
|
|
polyadenylation dependent mrna catabolic process
|
GO:0071047 |
1 |
0.303
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.301
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.298
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.298
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.291
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.287
|
|
|
|
response to genistein
|
GO:0033595 |
1 |
0.287
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.284
|
|
|
|
positive regulation of signal transduction by p53 class mediator
|
GO:1901798 |
10 |
0.283
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.282
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.280
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.278
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
10 |
0.275
|
|
|
|
regulation of glucocorticoid receptor signaling pathway
|
GO:2000322 |
2 |
0.273
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.273
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.273
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.272
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.271
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.271
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.267
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.264
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.263
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.259
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.255
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.254
|
Mouse |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.253
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.252
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.250
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.250
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.246
|
Human |
|
|
epidermis development
|
GO:0008544 |
59 |
0.245
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.243
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.239
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.239
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.233
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.232
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.230
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.228
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.228
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.227
|
Mouse |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.227
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.224
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.223
|
Mouse |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.217
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.216
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.214
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.214
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.212
|
|
|
|
positive regulation of cardiac muscle cell differentiation
|
GO:2000727 |
4 |
0.210
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.208
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.207
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.207
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.206
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.202
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.202
|
|
|
|
regulation of skeletal muscle cell differentiation
|
GO:2001014 |
3 |
0.197
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.197
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.194
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.191
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.191
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.190
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.189
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.186
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.186
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
3 |
0.185
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.181
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.181
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.180
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.177
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.176
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.175
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.174
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.174
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.173
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.172
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.171
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.171
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.170
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.169
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.168
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.168
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.165
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.165
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.164
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.164
|
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.163
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.162
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.162
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.162
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.160
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.159
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.157
|
Mouse |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.154
|
Mouse |
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
15 |
0.153
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.152
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.151
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.151
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.151
|
|
|
|
negative regulation of small gtpase mediated signal transduction
|
GO:0051058 |
12 |
0.150
|
|
|
|
ornithine metabolic process
|
GO:0006591 |
3 |
0.150
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.149
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.145
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.144
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.144
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.142
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.140
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.140
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.139
|
|
|
|
regulation of cardiac muscle cell differentiation
|
GO:2000725 |
7 |
0.139
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.138
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.137
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.134
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.134
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
18 |
0.133
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.133
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.133
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.132
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.131
|
Mouse |
|
|
cell activation
|
GO:0001775 |
213 |
0.131
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.130
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.129
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.128
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.127
|
Mouse |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.124
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.124
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.124
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.123
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.122
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.119
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.119
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.116
|
|
|
|
lymphatic endothelial cell fate commitment
|
GO:0060838 |
2 |
0.115
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.115
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.114
|
|
|
|
head development
|
GO:0060322 |
108 |
0.114
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.113
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.113
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.111
|
|
|
|
positive regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033145 |
7 |
0.111
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.110
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.110
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.109
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.109
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.109
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.108
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.107
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.107
|
Mouse |
|
|
positive regulation of organic acid transport
|
GO:0032892 |
3 |
0.105
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.104
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.104
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.104
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.104
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.104
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.103
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.103
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.102
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
23 |
0.101
|
|
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
6 |
0.100
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.099
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.099
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.096
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.096
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.096
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.095
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.094
|
|
|
|
corticosteroid receptor signaling pathway
|
GO:0031958 |
5 |
0.093
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.092
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.092
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.091
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.091
|
|
|
|
positive regulation of gluconeogenesis
|
GO:0045722 |
1 |
0.090
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.089
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.089
|
|
|
|
inositol phosphate mediated signaling
|
GO:0048016 |
16 |
0.089
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.088
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.088
|
|
|
|
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoter
|
GO:0035947 |
1 |
0.088
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.087
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.087
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.086
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.086
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.086
|
Mouse |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.086
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.085
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.085
|
|
|
|
heart growth
|
GO:0060419 |
6 |
0.085
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.084
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.084
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.084
|
|
|
|
response to zinc ion
|
GO:0010043 |
12 |
0.084
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.084
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.083
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.083
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.083
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.082
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.082
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.082
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.081
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.080
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.080
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.079
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.079
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.078
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.077
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.077
|
Mouse |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.077
|
|
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
5 |
0.077
|
Human |
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.077
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.076
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.076
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.075
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.075
|
Mouse |
|
|
nuclear transcribed mrna catabolic process
|
GO:0000956 |
48 |
0.075
|
|
|
|
response to glucagon
|
GO:0033762 |
1 |
0.075
|
|
|
|
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter
|
GO:0072367 |
4 |
0.075
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.074
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.074
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.074
|
|
|
|
translation
|
GO:0006412 |
132 |
0.074
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
53 |
0.074
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.073
|
|
|
|
maternal placenta development
|
GO:0001893 |
5 |
0.072
|
|
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.072
|
Human |
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.071
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.071
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.071
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.071
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.071
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.070
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.070
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.069
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.069
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.069
|
|
|
|
female pregnancy
|
GO:0007565 |
17 |
0.068
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.067
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.067
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.067
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.067
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.066
|
Human |
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.066
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.066
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.066
|
Mouse |
|
|
steroid hormone mediated signaling pathway
|
GO:0043401 |
12 |
0.066
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.064
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.064
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.063
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.063
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.063
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.063
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.063
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.063
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.063
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.062
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.061
|
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.061
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
4 |
0.061
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.061
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.060
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.060
|
|
|
|
regulation of type b pancreatic cell apoptotic process
|
GO:2000674 |
3 |
0.060
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.060
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.060
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.059
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.059
|
|
|
|
response to mercury ion
|
GO:0046689 |
4 |
0.058
|
|
|
|
mammary gland development
|
GO:0030879 |
17 |
0.058
|
Mouse |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.057
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.056
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
5 |
0.056
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.056
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.056
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.055
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.055
|
Mouse |
|
|
cellular hormone metabolic process
|
GO:0034754 |
41 |
0.055
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.055
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.054
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.054
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.054
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.054
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.054
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.054
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.054
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.053
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.053
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.053
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.053
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.052
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.051
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.051
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.051
|
|
|
|
nuclear transcribed mrna catabolic process nonsense mediated decay
|
GO:0000184 |
23 |
0.051
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.051
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.050
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.050
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.049
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.049
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.049
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.049
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.049
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.049
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.048
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.048
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.048
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.048
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.048
|
|
|
|
i kappab phosphorylation
|
GO:0007252 |
7 |
0.048
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.047
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.047
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.047
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.047
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.047
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.047
|
Human |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.047
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.046
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.046
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.046
|
|
|
|
regulation of transcription involved in cell fate commitment
|
GO:0060850 |
6 |
0.046
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.046
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.045
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.045
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.045
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.045
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.045
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.045
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.045
|
Human |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.044
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.044
|
|
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
14 |
0.044
|
|
|
|
placenta development
|
GO:0001890 |
10 |
0.044
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.044
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
17 |
0.044
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.044
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.044
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.044
|
|
|
|
regulation of transcription by chromatin organization
|
GO:0034401 |
1 |
0.043
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.043
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.043
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.043
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.043
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.043
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.043
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.043
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.043
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.042
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.042
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.042
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.042
|
|
|
|
response to nutrient
|
GO:0007584 |
20 |
0.042
|
Human |
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.042
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.041
|
|
|
|
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0017055 |
2 |
0.041
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
16 |
0.041
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.041
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.041
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.041
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.041
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.041
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.040
|
|
|
|
face development
|
GO:0060324 |
12 |
0.040
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.040
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.040
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.040
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.040
|
Mouse |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.040
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.040
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.040
|
|
|
|
xenobiotic metabolic process
|
GO:0006805 |
28 |
0.040
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.040
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.040
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.040
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.039
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.039
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.039
|
|
|
|
demethylation
|
GO:0070988 |
37 |
0.038
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
2 |
0.038
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.038
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.037
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.037
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.037
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.037
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.037
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
18 |
0.037
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.037
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.037
|
|
|
|
negative regulation of toll like receptor 4 signaling pathway
|
GO:0034144 |
4 |
0.036
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.036
|
|
|
|
ventricular cardiac muscle cell differentiation
|
GO:0055012 |
1 |
0.036
|
|
