Homo sapiens

8 known processes

NDUFS2

NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)

(Aliases: CI-49)

NDUFS2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
atp metabolic process GO:0046034 176 0.995
Worm
purine nucleoside monophosphate metabolic process GO:0009126 186 0.985
Worm
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.983
Worm
atp synthesis coupled electron transport GO:0042773 4 0.982
Worm
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.979
Worm
nucleoside monophosphate metabolic process GO:0009123 191 0.933
Worm
nadh dehydrogenase complex assembly GO:0010257 16 0.879
mitochondrial respiratory chain complex assembly GO:0033108 23 0.877
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.863
Worm
multicellular organismal aging GO:0010259 3 0.844
Worm
nucleoside triphosphate metabolic process GO:0009141 422 0.830
Worm
energy derivation by oxidation of organic compounds GO:0015980 43 0.795
Worm
mitochondrial electron transport nadh to ubiquinone GO:0006120 2 0.788
Worm
ribonucleoside monophosphate metabolic process GO:0009161 187 0.781
Worm
tricarboxylic acid cycle GO:0006099 4 0.759
ribonucleoside triphosphate metabolic process GO:0009199 412 0.705
Worm
post embryonic development GO:0009791 2 0.696
Worm
purine ribonucleoside metabolic process GO:0046128 437 0.690
Worm
generation of precursor metabolites and energy GO:0006091 68 0.640
Worm
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.630
determination of adult lifespan GO:0008340 2 0.561
Worm
oxidation reduction process GO:0055114 396 0.503
purine nucleoside triphosphate metabolic process GO:0009144 412 0.499
Worm
cellular respiration GO:0045333 21 0.422
Worm
mitochondrion organization GO:0007005 156 0.404
response to hypoxia GO:0001666 96 0.263
mitochondrial respiratory chain complex i assembly GO:0032981 16 0.250
isocitrate metabolic process GO:0006102 1 0.249
mitochondrial membrane organization GO:0007006 40 0.224
embryo development GO:0009790 123 0.223
Worm
oxidative phosphorylation GO:0006119 10 0.222
Worm
membrane organization GO:0061024 292 0.191
respiratory electron transport chain GO:0022904 7 0.172
Worm
vesicle mediated transport GO:0016192 371 0.163
Worm
electron transport chain GO:0022900 8 0.159
Worm
citrate metabolic process GO:0006101 2 0.159
myosin filament assembly GO:0031034 2 0.149
energy coupled proton transport down electrochemical gradient GO:0015985 2 0.136
succinate metabolic process GO:0006105 1 0.118
cardiovascular system development GO:0072358 262 0.109
anatomical structure formation involved in morphogenesis GO:0048646 284 0.103
purine ribonucleoside biosynthetic process GO:0046129 23 0.101
cation transport GO:0006812 331 0.098
monocarboxylic acid metabolic process GO:0032787 185 0.095
lipid metabolic process GO:0006629 381 0.093
cellular protein complex assembly GO:0043623 188 0.089
neuroblast proliferation GO:0007405 4 0.088
ribose phosphate biosynthetic process GO:0046390 82 0.087
aging GO:0007568 66 0.085
Worm
nervous system development GO:0007399 293 0.085
cellular macromolecular complex assembly GO:0034622 324 0.082
intracellular protein transport GO:0006886 270 0.079
defense response GO:0006952 315 0.070
reactive oxygen species metabolic process GO:0072593 75 0.066
response to decreased oxygen levels GO:0036293 96 0.063
intracellular protein transmembrane transport GO:0065002 24 0.060
response to oxygen levels GO:0070482 100 0.059
system process GO:0003008 349 0.057
protein maturation GO:0051604 233 0.054
endocytosis GO:0006897 159 0.054
Worm
mitochondrial transport GO:0006839 60 0.054
lipid catabolic process GO:0016042 84 0.052
transmembrane transport GO:0055085 399 0.049
growth GO:0040007 202 0.046
fatty acid metabolic process GO:0006631 115 0.044
response to drug GO:0042493 81 0.044
Worm
chemical homeostasis GO:0048878 306 0.043
lipid oxidation GO:0034440 33 0.039
regulation of proteolysis GO:0030162 293 0.039
circulatory system development GO:0072359 262 0.039
actin filament based process GO:0030029 224 0.038
biological adhesion GO:0022610 331 0.038
monocarboxylic acid catabolic process GO:0072329 37 0.037
oogenesis GO:0048477 2 0.036
regulation of nucleoside metabolic process GO:0009118 209 0.035
female gamete generation GO:0007292 2 0.035
central nervous system development GO:0007417 123 0.035
receptor mediated endocytosis GO:0006898 84 0.033
Worm
response to abiotic stimulus GO:0009628 336 0.033
negative regulation of apoptotic signaling pathway GO:2001234 97 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.032
neuromuscular junction development GO:0007528 3 0.032
carbohydrate derivative biosynthetic process GO:1901137 207 0.031
inorganic ion transmembrane transport GO:0098660 231 0.031
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.030
regulation of endopeptidase activity GO:0052548 170 0.030
organic acid catabolic process GO:0016054 71 0.030
regulation of nucleotide catabolic process GO:0030811 205 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
cell growth GO:0016049 160 0.030
negative regulation of growth GO:0045926 97 0.030
protein localization to membrane GO:0072657 160 0.030
positive regulation of hydrolase activity GO:0051345 331 0.029
regulation of peptidase activity GO:0052547 180 0.029
cellular amino acid metabolic process GO:0006520 116 0.029
ribonucleotide biosynthetic process GO:0009260 81 0.028
embryonic morphogenesis GO:0048598 85 0.028
generation of neurons GO:0048699 152 0.028
organic hydroxy compound metabolic process GO:1901615 147 0.027
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.027
purine containing compound catabolic process GO:0072523 411 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
single organism membrane organization GO:0044802 268 0.027
ion transmembrane transport GO:0034220 338 0.026
actin cytoskeleton organization GO:0030036 207 0.026
negative regulation of cell death GO:0060548 345 0.026
inorganic anion transmembrane transport GO:0098661 47 0.026
positive regulation of apoptotic process GO:0043065 246 0.026
protein localization to organelle GO:0033365 280 0.026
cell adhesion GO:0007155 325 0.025
embryo development ending in birth or egg hatching GO:0009792 34 0.025
Worm
mating GO:0007618 1 0.025
nucleotide catabolic process GO:0009166 408 0.025
excretion GO:0007588 9 0.025
response to wounding GO:0009611 168 0.024
head development GO:0060322 108 0.024
carboxylic acid catabolic process GO:0046395 71 0.024
positive regulation of proteolysis GO:0045862 142 0.023
intrinsic apoptotic signaling pathway GO:0097193 127 0.023
ion homeostasis GO:0050801 230 0.023
protein processing GO:0016485 226 0.023
wound healing GO:0042060 115 0.023
response to other organism GO:0051707 261 0.023
positive regulation of cell death GO:0010942 263 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
metal ion transport GO:0030001 272 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
negative regulation of cell proliferation GO:0008285 228 0.022
negative regulation of programmed cell death GO:0043069 321 0.022
cytoplasmic transport GO:0016482 379 0.022
cellular ion homeostasis GO:0006873 168 0.022
single organism cellular localization GO:1902580 332 0.021
fatty acid oxidation GO:0019395 31 0.021
regulation of cell growth GO:0001558 135 0.021
sulfur compound metabolic process GO:0006790 101 0.021
organophosphate catabolic process GO:0046434 430 0.021
cellular component morphogenesis GO:0032989 314 0.020
brain development GO:0007420 97 0.020
cellular amine metabolic process GO:0044106 41 0.020
regulation of growth GO:0040008 165 0.020
monovalent inorganic cation transport GO:0015672 128 0.020
innate immune response GO:0045087 178 0.020
cardiac muscle tissue development GO:0048738 39 0.020
cellular cation homeostasis GO:0030003 163 0.019
spermatid differentiation GO:0048515 4 0.019
tricarboxylic acid metabolic process GO:0072350 4 0.019
cell part morphogenesis GO:0032990 137 0.019
anion transport GO:0006820 161 0.019
cellular lipid metabolic process GO:0044255 303 0.019
zymogen activation GO:0031638 70 0.019
muscle tissue development GO:0060537 62 0.018
locomotory behavior GO:0007626 1 0.018
aerobic respiration GO:0009060 7 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
substantia nigra development GO:0021762 45 0.018
response to external biotic stimulus GO:0043207 261 0.018
cation homeostasis GO:0055080 189 0.017
protein catabolic process GO:0030163 325 0.017
regulation of cell adhesion GO:0030155 166 0.017
ribonucleoside catabolic process GO:0042454 406 0.016
response to oxidative stress GO:0006979 121 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
myosin filament organization GO:0031033 2 0.016
adult locomotory behavior GO:0008344 1 0.016
regeneration GO:0031099 4 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
regulation of membrane potential GO:0042391 95 0.016
cation transmembrane transport GO:0098655 238 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
cell development GO:0048468 328 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
regulation of neurogenesis GO:0050767 82 0.015
establishment of protein localization to mitochondrial membrane GO:0090151 7 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.015
protein targeting GO:0006605 187 0.015
response to biotic stimulus GO:0009607 276 0.015
monovalent inorganic cation homeostasis GO:0055067 37 0.015
cellular chemical homeostasis GO:0055082 180 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
inner mitochondrial membrane organization GO:0007007 8 0.015
spinal cord development GO:0021510 4 0.015
midbrain development GO:0030901 45 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
cellular response to cytokine stimulus GO:0071345 181 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
striated muscle myosin thick filament assembly GO:0071688 2 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
response to cytokine GO:0034097 232 0.014
purine nucleotide biosynthetic process GO:0006164 84 0.014
maintenance of location GO:0051235 112 0.014
regulation of transferase activity GO:0051338 355 0.013
regulation of gtpase activity GO:0043087 180 0.013
dicarboxylic acid catabolic process GO:0043649 9 0.013
regulation of protein kinase activity GO:0045859 289 0.013
lipid storage GO:0019915 28 0.013
response to oxygen containing compound GO:1901700 369 0.013
regulation of cellular amino acid metabolic process GO:0006521 6 0.013
glycerol metabolic process GO:0006071 4 0.013
immune response GO:0006955 307 0.013
lipid localization GO:0010876 106 0.013
regulation of kinase activity GO:0043549 314 0.013
cofactor biosynthetic process GO:0051188 31 0.013
regulation of membrane permeability GO:0090559 25 0.013
reproduction GO:0000003 63 0.012
Worm
hydrogen transport GO:0006818 23 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
spermatid development GO:0007286 4 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
negative regulation of cell adhesion GO:0007162 64 0.012
reproductive system development GO:0061458 56 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
cell differentiation in spinal cord GO:0021515 1 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
neuron differentiation GO:0030182 138 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
behavior GO:0007610 112 0.011
neural nucleus development GO:0048857 47 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
nitrogen compound transport GO:0071705 191 0.011
negative regulation of cell growth GO:0030308 83 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
apoptotic nuclear changes GO:0030262 13 0.011
positive regulation of catabolic process GO:0009896 310 0.011
rho protein signal transduction GO:0007266 26 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
muscle system process GO:0003012 81 0.011
ventral spinal cord development GO:0021517 1 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
nucleotide biosynthetic process GO:0009165 109 0.010
cell cell signaling GO:0007267 155 0.010
dicarboxylic acid metabolic process GO:0043648 29 0.010
actomyosin structure organization GO:0031032 59 0.010
regulation of cell development GO:0060284 161 0.010

NDUFS2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.996
inherited metabolic disorder DOID:655 242 0.996
leigh disease DOID:3652 16 0.989
mitochondrial metabolism disease DOID:700 29 0.989
endocrine gland cancer DOID:170 26 0.392
cancer DOID:162 167 0.392
disease of cellular proliferation DOID:14566 174 0.392
organ system cancer DOID:0050686 164 0.392
heart disease DOID:114 68 0.225
cardiovascular system disease DOID:1287 106 0.225
muscular disease DOID:0080000 114 0.113
musculoskeletal system disease DOID:17 223 0.113
myopathy DOID:423 104 0.100
muscle tissue disease DOID:66 113 0.100
retinal disease DOID:5679 118 0.066
sensory system disease DOID:0050155 203 0.066
eye and adnexa disease DOID:1492 150 0.066
nervous system disease DOID:863 431 0.066
eye disease DOID:5614 149 0.066
gastrointestinal system cancer DOID:3119 52 0.054
cardiomyopathy DOID:0050700 50 0.038
central nervous system disease DOID:331 186 0.036
dilated cardiomyopathy DOID:12930 32 0.035
intrinsic cardiomyopathy DOID:0060036 50 0.035
amino acid metabolic disorder DOID:9252 50 0.034
neuromuscular disease DOID:440 38 0.021
neuropathy DOID:870 52 0.021
retinal degeneration DOID:8466 89 0.015
coenzyme q10 deficiency disease DOID:0050730 6 0.011
retinitis pigmentosa DOID:10584 51 0.010