Homo sapiens

113 known processes

NEDD4L

neural precursor cell expressed, developmentally down-regulated 4-like

(Aliases: hNedd4-2,KIAA0439,NEDD4-2,RSP5,FLJ33870)

NEDD4L biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sodium ion transport GO:0006814 61 0.999
drinking behavior GO:0042756 1 0.999
inorganic ion transmembrane transport GO:0098660 231 0.997
regulation of sodium ion transport GO:0002028 24 0.996
cation transmembrane transport GO:0098655 238 0.990
sodium ion transmembrane transport GO:0035725 59 0.988
regulation of metal ion transport GO:0010959 120 0.984
regulation of sodium ion transmembrane transport GO:1902305 23 0.982
regulation of ion transport GO:0043269 189 0.982
regulation of transporter activity GO:0032409 82 0.976
ion transmembrane transport GO:0034220 338 0.974
metal ion transport GO:0030001 272 0.972
monovalent inorganic cation transport GO:0015672 128 0.970
cation transport GO:0006812 331 0.969
ion homeostasis GO:0050801 230 0.917
regulation of ion transmembrane transporter activity GO:0032412 72 0.915
chemical homeostasis GO:0048878 306 0.913
regulation of ion transmembrane transport GO:0034765 132 0.881
transmembrane transport GO:0055085 399 0.871
regulation of rubidium ion transmembrane transporter activity GO:2000686 2 0.856
regulation of transmembrane transport GO:0034762 139 0.828
sodium ion homeostasis GO:0055078 14 0.828
epithelium development GO:0060429 227 0.793
regulation of transmembrane transporter activity GO:0022898 74 0.782
inorganic cation transmembrane transport GO:0098662 194 0.776
regulation of sodium ion transmembrane transporter activity GO:2000649 17 0.767
regulation of protein localization GO:0032880 296 0.741
single organism cellular localization GO:1902580 332 0.726
Human
negative regulation of transport GO:0051051 176 0.715
regulation of potassium ion transmembrane transport GO:1901379 20 0.708
organ morphogenesis GO:0009887 147 0.689
cellular component morphogenesis GO:0032989 314 0.688
Yeast
negative regulation of multicellular organismal process GO:0051241 317 0.686
neuron differentiation GO:0030182 138 0.680
Human
protein modification by small protein conjugation GO:0032446 342 0.643
membrane organization GO:0061024 292 0.642
regulation of kinase activity GO:0043549 314 0.626
potassium ion transmembrane transport GO:0071805 60 0.618
negative regulation of programmed cell death GO:0043069 321 0.612
Human
regulation of protein kinase activity GO:0045859 289 0.600
positive regulation of phosphorylation GO:0042327 394 0.600
positive regulation of cellular amine metabolic process GO:0033240 7 0.599
guanosine containing compound metabolic process GO:1901068 244 0.589
metal ion homeostasis GO:0055065 169 0.585
response to abiotic stimulus GO:0009628 336 0.556
Human Yeast Mouse
cell morphogenesis GO:0000902 296 0.544
Yeast
detection of mechanical stimulus GO:0050982 4 0.542
negative regulation of cell proliferation GO:0008285 228 0.538
protein autophosphorylation GO:0046777 123 0.538
positive regulation of catabolic process GO:0009896 310 0.536
Human Yeast
erk1 and erk2 cascade GO:0070371 104 0.523
potassium ion transport GO:0006813 62 0.512
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.507
Human
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.500
Human
positive regulation of ion transport GO:0043270 87 0.497
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.495
purine nucleoside triphosphate catabolic process GO:0009146 392 0.493
response to salt stress GO:0009651 3 0.481
Mouse
positive regulation of wnt signaling pathway GO:0030177 54 0.480
ribonucleoside catabolic process GO:0042454 406 0.476
cellular ketone metabolic process GO:0042180 80 0.474
Yeast
rubidium ion transport GO:0035826 4 0.471
regulation of transferase activity GO:0051338 355 0.464
regulation of establishment of protein localization GO:0070201 242 0.452
Human
regulation of body fluid levels GO:0050878 99 0.451
regulation of cofactor metabolic process GO:0051193 3 0.445
Yeast
regulation of rubidium ion transport GO:2000680 3 0.442
nucleoside triphosphate metabolic process GO:0009141 422 0.438
cellular potassium ion transport GO:0071804 60 0.436
neuron projection development GO:0031175 106 0.435
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.430
Human
negative regulation of sodium ion transmembrane transporter activity GO:2000650 2 0.429
cell projection organization GO:0030030 252 0.420
Human Yeast
positive regulation of cellular component organization GO:0051130 376 0.419
Yeast
regulation of potassium ion transport GO:0043266 24 0.419
purine nucleotide catabolic process GO:0006195 405 0.414
system process GO:0003008 349 0.406
Mouse
multicellular organismal aging GO:0010259 3 0.399
regulation of ion homeostasis GO:2000021 73 0.394
purine containing compound catabolic process GO:0072523 411 0.388
negative regulation of sodium ion transmembrane transport GO:1902306 2 0.377
cellular response to abiotic stimulus GO:0071214 117 0.377
Human Yeast
renal tubule morphogenesis GO:0061333 14 0.375
pancreatic juice secretion GO:0030157 4 0.375
tissue morphogenesis GO:0048729 96 0.375
female gamete generation GO:0007292 2 0.372
purine ribonucleoside metabolic process GO:0046128 437 0.371
response to oxygen containing compound GO:1901700 369 0.369
negative regulation of feeding behavior GO:2000252 1 0.367
cell morphogenesis involved in differentiation GO:0000904 144 0.367
gtp metabolic process GO:0046039 239 0.366
trna transport GO:0051031 1 0.366
Yeast
cytoplasmic transport GO:0016482 379 0.363
Human Yeast
mating GO:0007618 1 0.362
regulation of cellular component biogenesis GO:0044087 281 0.361
Yeast Mouse
morphogenesis of an epithelium GO:0002009 60 0.360
nephron epithelium morphogenesis GO:0072088 15 0.358
cation homeostasis GO:0055080 189 0.354
mapk cascade GO:0000165 288 0.350
cellular response to endogenous stimulus GO:0071495 336 0.346
Human
negative regulation of apoptotic process GO:0043066 316 0.344
Human
positive regulation of gtpase activity GO:0043547 166 0.341
polyprenol biosynthetic process GO:0016094 1 0.338
Yeast
ribonucleotide catabolic process GO:0009261 405 0.337
regulation of nucleotide metabolic process GO:0006140 269 0.336
neurogenesis GO:0022008 169 0.335
Human
canonical wnt signaling pathway GO:0060070 116 0.333
single organism membrane organization GO:0044802 268 0.332
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.331
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.331
cell cell junction organization GO:0045216 69 0.327
Mouse
kidney epithelium development GO:0072073 25 0.326
small gtpase mediated signal transduction GO:0007264 78 0.323
post embryonic development GO:0009791 2 0.323
renal sodium ion transport GO:0003096 2 0.321
ribonucleoside triphosphate catabolic process GO:0009203 391 0.321
protein k29 linked ubiquitination GO:0035519 4 0.320
Human
mechanosensory behavior GO:0007638 4 0.318
nucleoside triphosphate catabolic process GO:0009143 394 0.310
cellular response to oxygen containing compound GO:1901701 276 0.310
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.309
oogenesis GO:0048477 2 0.309
forebrain generation of neurons GO:0021872 3 0.304
cellular amino acid metabolic process GO:0006520 116 0.298
nucleoside catabolic process GO:0009164 408 0.296
regulation of feeding behavior GO:0060259 3 0.294
dolichol biosynthetic process GO:0019408 1 0.292
Yeast
positive regulation of kinase activity GO:0033674 204 0.291
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.289
organic hydroxy compound metabolic process GO:1901615 147 0.287
Yeast
cell fate determination GO:0001709 3 0.287
positive regulation of transport GO:0051050 336 0.287
Human Yeast Mouse
cell development GO:0048468 328 0.286
Human
regulation of homeostatic process GO:0032844 121 0.283
gtp catabolic process GO:0006184 237 0.282
endocardial cushion development GO:0003197 3 0.279
sensory perception of chemical stimulus GO:0007606 38 0.279
regulation of mapk cascade GO:0043408 262 0.277
purine ribonucleoside catabolic process GO:0046130 398 0.273
positive regulation of hydrolase activity GO:0051345 331 0.272
regulation of nucleotide catabolic process GO:0030811 205 0.268
regulation of actin cytoskeleton organization GO:0032956 116 0.267
Yeast
regulation of gtp catabolic process GO:0033124 180 0.266
signal transduction by phosphorylation GO:0023014 297 0.265
purine nucleoside triphosphate metabolic process GO:0009144 412 0.262
regulation of cellular amine metabolic process GO:0033238 11 0.262
response to transforming growth factor beta GO:0071559 94 0.262
Human
trna export from nucleus GO:0006409 1 0.261
Yeast
regulation of protein localization to plasma membrane GO:1903076 40 0.260
regulation of purine nucleotide metabolic process GO:1900542 264 0.260
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.259
Yeast
sensory perception of taste GO:0050909 36 0.257
positive regulation of systemic arterial blood pressure GO:0003084 2 0.257
positive regulation of nucleotide catabolic process GO:0030813 185 0.257
positive regulation of sodium ion transmembrane transport GO:1902307 9 0.256
cell junction organization GO:0034330 79 0.253
Mouse
regulation of cell morphogenesis GO:0022604 153 0.253
Yeast
transmission of virus GO:0019089 1 0.251
Human
ribosomal large subunit export from nucleus GO:0000055 3 0.251
Yeast
regulation of cytoskeleton organization GO:0051493 177 0.244
Yeast
regulation of purine nucleotide catabolic process GO:0033121 205 0.243
organophosphate catabolic process GO:0046434 430 0.242
cell projection morphogenesis GO:0048858 129 0.240
protein localization to membrane GO:0072657 160 0.238
negative regulation of cell death GO:0060548 345 0.237
Human
negative regulation of ion transmembrane transport GO:0034766 26 0.236
cell cell signaling GO:0007267 155 0.236
regulation of protein transport GO:0051223 213 0.235
Human
negative regulation of sodium ion transport GO:0010766 3 0.235
single organism cell adhesion GO:0098602 179 0.233
nucleoside phosphate catabolic process GO:1901292 412 0.231
positive regulation of blood pressure GO:0045777 3 0.229
water homeostasis GO:0030104 14 0.225
regulation of wnt signaling pathway GO:0030111 123 0.221
regulation of ketone biosynthetic process GO:0010566 7 0.221
Yeast
purine nucleoside catabolic process GO:0006152 398 0.221
regulation of mrna export from nucleus GO:0010793 3 0.220
Yeast
positive regulation of nucleotide metabolic process GO:0045981 230 0.220
negative regulation of protein metabolic process GO:0051248 391 0.219
cellular response to growth factor stimulus GO:0071363 197 0.217
Human
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.215
distal tubule development GO:0072017 4 0.213
detection of stimulus GO:0051606 85 0.208
response to decreased oxygen levels GO:0036293 96 0.206
positive regulation of cytoplasmic transport GO:1903651 82 0.204
Human
actin filament based process GO:0030029 224 0.203
Yeast
response to inorganic substance GO:0010035 127 0.203
kidney morphogenesis GO:0060993 19 0.202
regulation of protein ubiquitination GO:0031396 95 0.201
protein localization to plasma membrane GO:0072659 93 0.196
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.194
regulation of system process GO:0044057 101 0.192
negative regulation of protein modification process GO:0031400 200 0.192
nuclear transport GO:0051169 179 0.191
Human Yeast
behavior GO:0007610 112 0.191
regulation of ras protein signal transduction GO:0046578 155 0.185
positive regulation of transmembrane transport GO:0034764 41 0.185
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.182
kidney development GO:0001822 53 0.180
nucleotide catabolic process GO:0009166 408 0.179
regulation of vesicle mediated transport GO:0060627 130 0.178
Yeast
negative regulation of phosphorylation GO:0042326 174 0.178
circulatory system process GO:0003013 113 0.177
Mouse
glycosyl compound catabolic process GO:1901658 413 0.176
neuron development GO:0048666 113 0.174
Human
cellular response to water stimulus GO:0071462 1 0.173
positive regulation of transferase activity GO:0051347 227 0.173
positive regulation of gtp catabolic process GO:0033126 166 0.172
purine ribonucleotide catabolic process GO:0009154 404 0.171
positive regulation of cellular catabolic process GO:0031331 284 0.170
Yeast
regulation of anatomical structure morphogenesis GO:0022603 286 0.169
Yeast
determination of adult lifespan GO:0008340 2 0.169
negative regulation of cellular component organization GO:0051129 235 0.166
epithelial cell differentiation GO:0030855 141 0.166
dolichol metabolic process GO:0019348 3 0.164
Yeast
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.163
Human
modification dependent protein catabolic process GO:0019941 209 0.162
negative regulation of ion transport GO:0043271 39 0.162
cell adhesion GO:0007155 325 0.162
regulation of actin filament based process GO:0032970 141 0.162
Yeast
negative regulation of intracellular signal transduction GO:1902532 183 0.162
regulation of protein serine threonine kinase activity GO:0071900 179 0.161
mitotic cell cycle process GO:1903047 286 0.161
establishment of protein localization to membrane GO:0090150 121 0.160
detection of abiotic stimulus GO:0009582 15 0.160
locomotory behavior GO:0007626 1 0.159
protein k48 linked ubiquitination GO:0070936 38 0.155
regulation of gtpase activity GO:0043087 180 0.155
detection of mechanical stimulus involved in sensory perception GO:0050974 1 0.154
nervous system development GO:0007399 293 0.154
Human
dephosphorylation GO:0016311 209 0.153
ribonucleoprotein complex export from nucleus GO:0071426 4 0.152
Yeast
regulation of nucleoside metabolic process GO:0009118 209 0.151
amine metabolic process GO:0009308 44 0.150
negative regulation of protein phosphorylation GO:0001933 140 0.150
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.150
response to growth factor GO:0070848 205 0.150
Human
establishment of ribosome localization GO:0033753 4 0.149
Yeast
regulation of erk1 and erk2 cascade GO:0070372 99 0.149
cell part morphogenesis GO:0032990 137 0.149
intracellular protein transport GO:0006886 270 0.149
Human
secretion GO:0046903 254 0.148
protein monoubiquitination GO:0006513 39 0.148
Yeast
atrioventricular valve development GO:0003171 3 0.147
ubiquitin dependent endocytosis GO:0070086 1 0.146
Yeast
response to other organism GO:0051707 261 0.146
Human
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.145
regulation of endosome size GO:0051036 3 0.145
Yeast
ketone biosynthetic process GO:0042181 17 0.145
Yeast
regulation of calcium ion transport GO:0051924 79 0.144
negative regulation of digestive system process GO:0060457 2 0.144
ribonucleoside triphosphate metabolic process GO:0009199 412 0.144
i kappab kinase nf kappab signaling GO:0007249 166 0.143
adherens junction organization GO:0034332 36 0.143
nephron tubule morphogenesis GO:0072078 13 0.142
cell projection assembly GO:0030031 126 0.142
Yeast
positive regulation of cell differentiation GO:0045597 211 0.141
regulation of cellular component movement GO:0051270 334 0.141
positive regulation of intracellular transport GO:0032388 104 0.139
Human
ras protein signal transduction GO:0007265 73 0.138
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.137
Mouse
positive regulation of protein kinase activity GO:0045860 190 0.136
renal tubule development GO:0061326 19 0.133
positive regulation of ras gtpase activity GO:0032320 117 0.133
membrane repolarization GO:0086009 23 0.133
chemotaxis GO:0006935 157 0.133
quinone metabolic process GO:1901661 18 0.132
Yeast
mitotic cell cycle GO:0000278 326 0.132
positive regulation of ion transmembrane transport GO:0034767 40 0.132
Mouse
progesterone receptor signaling pathway GO:0050847 3 0.132
Human
cellular amine metabolic process GO:0044106 41 0.131
positive regulation of calcium ion transport GO:0051928 51 0.131
anterior posterior axis specification GO:0009948 2 0.130
chromatin organization GO:0006325 351 0.129
Yeast
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.128
calcium ion transport GO:0006816 147 0.127
peptidyl threonine modification GO:0018210 45 0.127
isoprenoid metabolic process GO:0006720 39 0.127
Yeast
regulation of canonical wnt signaling pathway GO:0060828 88 0.127
neurotransmitter secretion GO:0007269 4 0.127
positive regulation of cell motility GO:2000147 177 0.126
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.125
maintenance of location in cell GO:0051651 62 0.124
vesicle mediated transport GO:0016192 371 0.124
Human Yeast
response to hypoxia GO:0001666 96 0.124
positive regulation of sodium ion transmembrane transporter activity GO:2000651 6 0.123
innate immune response GO:0045087 178 0.123
protein catabolic process GO:0030163 325 0.123
cellular macromolecule catabolic process GO:0044265 380 0.121
regulation of neurotransmitter secretion GO:0046928 3 0.119
regulation of nucleocytoplasmic transport GO:0046822 98 0.118
Human Yeast
protein polyubiquitination GO:0000209 110 0.118
negative regulation of protein localization to cell surface GO:2000009 5 0.117
single organismal cell cell adhesion GO:0016337 148 0.117
positive regulation of nucleoside metabolic process GO:0045979 186 0.116
regulation of secretion GO:0051046 194 0.116
establishment of planar polarity GO:0001736 3 0.116
dissemination or transmission of organism from other organism involved in symbiotic interaction GO:0051821 1 0.116
Human
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.115
Human
establishment of organelle localization GO:0051656 59 0.115
Yeast
sodium ion export from cell GO:0036376 6 0.114
negative regulation of dna metabolic process GO:0051053 57 0.113
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.110
axonogenesis GO:0007409 31 0.110
divalent inorganic cation transport GO:0072511 158 0.110
cellular component disassembly GO:0022411 92 0.109
neuroblast proliferation GO:0007405 4 0.109
neuron projection morphogenesis GO:0048812 50 0.109
regulation of endothelial cell migration GO:0010594 67 0.109
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.108
ubiquitin dependent protein catabolic process GO:0006511 206 0.108
defense response GO:0006952 315 0.108
Human
regulation of proteolysis GO:0030162 293 0.106
Yeast
regulation of rrna processing GO:2000232 1 0.105
Yeast
regulation of cell differentiation GO:0045595 393 0.103
somatic stem cell division GO:0048103 1 0.102
rho protein signal transduction GO:0007266 26 0.102
proteasomal protein catabolic process GO:0010498 176 0.100
microtubule cytoskeleton organization GO:0000226 176 0.099
divalent metal ion transport GO:0070838 152 0.098
nephron morphogenesis GO:0072028 15 0.098
adherens junction assembly GO:0034333 34 0.098
negative regulation of catalytic activity GO:0043086 335 0.098
ribonucleoprotein complex localization GO:0071166 4 0.098
Yeast
renal absorption GO:0070293 6 0.098
oxidoreduction coenzyme metabolic process GO:0006733 19 0.097
Yeast
bmp signaling pathway GO:0030509 49 0.097
Human
plasma membrane organization GO:0007009 115 0.097
multicellular organismal response to stress GO:0033555 1 0.097
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.096
wnt signaling pathway GO:0016055 156 0.096
protein localization to organelle GO:0033365 280 0.095
Human
melanin metabolic process GO:0006582 1 0.095
maintenance of location GO:0051235 112 0.094
positive regulation of sodium ion transport GO:0010765 14 0.094
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.093
biological adhesion GO:0022610 331 0.093
negative regulation of cellular protein metabolic process GO:0032269 353 0.092
regulation of small gtpase mediated signal transduction GO:0051056 156 0.092
negative regulation of transporter activity GO:0032410 25 0.091
distal tubule morphogenesis GO:0072156 3 0.091
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.090
Yeast
negative regulation of multi organism process GO:0043901 92 0.090
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.090
regulation of cell junction assembly GO:1901888 29 0.089
Mouse
modification dependent macromolecule catabolic process GO:0043632 212 0.089
endothelium development GO:0003158 33 0.089
regulation of cellular ketone metabolic process GO:0010565 50 0.087
Yeast
axon development GO:0061564 34 0.087
positive regulation of mapk cascade GO:0043410 190 0.087
dissemination or transmission of symbiont from host GO:0044007 1 0.087
Human
guanosine containing compound catabolic process GO:1901069 239 0.085
polyprenol metabolic process GO:0016093 3 0.085
Yeast
positive regulation of transporter activity GO:0032411 32 0.085
Mouse
tripartite regional subdivision GO:0007351 2 0.085
protein ubiquitination GO:0016567 314 0.084
monovalent inorganic cation homeostasis GO:0055067 37 0.084
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.084
trna processing GO:0008033 23 0.084
Yeast
response to radiation GO:0009314 151 0.083
Human Yeast
defense response to other organism GO:0098542 129 0.083
Human
sensory perception of pain GO:0019233 4 0.083
negative regulation of developmental process GO:0051093 247 0.082
nephron development GO:0072006 30 0.082
synaptic transmission GO:0007268 61 0.082
nephron tubule development GO:0072080 17 0.082
negative regulation of protein transport GO:0051224 75 0.081
Human
digestion GO:0007586 22 0.080
endosomal transport GO:0016197 129 0.080
Yeast
negative regulation of cell motility GO:2000146 104 0.080
regulation of membrane potential GO:0042391 95 0.079
development involved in symbiotic interaction GO:0044111 1 0.079
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.078
regulation of cell migration GO:0030334 289 0.077
negative regulation of hydrolase activity GO:0051346 182 0.077
oocyte development GO:0048599 1 0.077
forebrain neuron development GO:0021884 2 0.076
positive regulation of actin filament bundle assembly GO:0032233 25 0.076
organelle localization GO:0051640 84 0.076
Yeast
anatomical structure formation involved in morphogenesis GO:0048646 284 0.075
Yeast
segmentation GO:0035282 4 0.074
regulation of activin receptor signaling pathway GO:0032925 14 0.074
negative regulation of trophoblast cell migration GO:1901164 3 0.073
regulation of digestive system process GO:0044058 5 0.073
microtubule based process GO:0007017 210 0.073
coenzyme biosynthetic process GO:0009108 24 0.073
Yeast
regulation of cell cycle GO:0051726 393 0.072
endothelial cell differentiation GO:0045446 26 0.071
wound healing GO:0042060 115 0.071
reproductive process GO:0022414 106 0.071
Yeast
regulation of epithelial cell migration GO:0010632 93 0.071
taxis GO:0042330 157 0.070
cellular ion homeostasis GO:0006873 168 0.070
motor neuron axon guidance GO:0008045 2 0.070
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.069
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.068
Human
regulation of cell projection organization GO:0031344 107 0.067
Yeast
ribosomal subunit export from nucleus GO:0000054 4 0.067
Yeast
endomembrane system organization GO:0010256 196 0.067
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.067
Human
maintenance of protein location GO:0045185 57 0.066
protein targeting GO:0006605 187 0.066
Human
golgi vesicle transport GO:0048193 80 0.065
cellular response to nitrogen compound GO:1901699 144 0.065
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.065
positive regulation of programmed cell death GO:0043068 249 0.065
multicellular organismal water homeostasis GO:0050891 14 0.065
response to oxygen levels GO:0070482 100 0.065
regulation of cell development GO:0060284 161 0.064
central nervous system development GO:0007417 123 0.064
response to light stimulus GO:0009416 87 0.064
Human Yeast
cell junction assembly GO:0034329 67 0.063
Mouse
oocyte differentiation GO:0009994 2 0.063
positive regulation of proteolysis GO:0045862 142 0.063
Yeast
protein deubiquitination GO:0016579 79 0.063
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.063
mitochondrion organization GO:0007005 156 0.063
Yeast
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage GO:0010767 1 0.063
Human
endothelial cell migration GO:0043542 86 0.061
positive regulation of neuron migration GO:2001224 1 0.061
nucleocytoplasmic transport GO:0006913 176 0.061
Human Yeast
regulation of ras gtpase activity GO:0032318 128 0.061
regulation of dna metabolic process GO:0051052 153 0.061
neurological system process GO:0050877 163 0.060
positive regulation of vasculogenesis GO:2001214 1 0.060
negative regulation of kinase activity GO:0033673 106 0.060
cellular protein catabolic process GO:0044257 261 0.059
vasculature development GO:0001944 181 0.059
cellular metal ion homeostasis GO:0006875 146 0.059
establishment of protein localization to plasma membrane GO:0090002 68 0.059
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.059
Human
cellular chemical homeostasis GO:0055082 180 0.058
regulation of protein catabolic process GO:0042176 155 0.057
Human Yeast
chromatin assembly or disassembly GO:0006333 78 0.057
Yeast
angiogenesis GO:0001525 147 0.057
regulation of isoprenoid metabolic process GO:0019747 1 0.057
Yeast
negative regulation of transmembrane transport GO:0034763 29 0.057
positive regulation of cell death GO:0010942 263 0.056
response to water GO:0009415 2 0.056
regulation of peptidase activity GO:0052547 180 0.056
nitrogen compound transport GO:0071705 191 0.056
Yeast
cellular response to organonitrogen compound GO:0071417 124 0.056
embryo development GO:0009790 123 0.056
mitral valve development GO:0003174 3 0.056
endocardial cell differentiation GO:0060956 2 0.055
regulation of cellular protein catabolic process GO:1903362 96 0.055
Yeast
regulation of vasculogenesis GO:2001212 3 0.055
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.054
Human
regulation of cell motility GO:2000145 299 0.054
coenzyme metabolic process GO:0006732 65 0.054
Yeast
wound healing spreading of epidermal cells GO:0035313 6 0.054
establishment of protein localization to organelle GO:0072594 172 0.054
Human
negative regulation of protein kinase activity GO:0006469 98 0.053
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.053
protein autoubiquitination GO:0051865 37 0.053
Human Yeast
cellular response to acid chemical GO:0071229 44 0.053
striated muscle tissue development GO:0014706 59 0.053
positive regulation of protein catabolic process GO:0045732 75 0.053
Human Yeast
generation of neurons GO:0048699 152 0.053
Human
blood circulation GO:0008015 113 0.052
Mouse
late endosome to vacuole transport GO:0045324 2 0.052
Yeast
brain development GO:0007420 97 0.051
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.051
Yeast
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.051
tube development GO:0035295 125 0.050
blood vessel endothelial cell migration GO:0043534 42 0.050
regulation of neuron projection development GO:0010975 57 0.048
stem cell differentiation GO:0048863 93 0.048
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.048
negative regulation of phosphatase activity GO:0010923 61 0.048
response to organic cyclic compound GO:0014070 204 0.048
muscle structure development GO:0061061 98 0.048
renal system development GO:0072001 63 0.048
positive regulation of dendritic cell apoptotic process GO:2000670 1 0.048
regulation of multi organism process GO:0043900 157 0.048
Human Yeast
regulation of blood pressure GO:0008217 30 0.047
Mouse
regulation of cell growth GO:0001558 135 0.047
negative regulation of chorionic trophoblast cell proliferation GO:1901383 2 0.047
regulation of multivesicular body size GO:0010796 1 0.047
Yeast
digestive system process GO:0022600 17 0.047
atrioventricular valve morphogenesis GO:0003181 2 0.047
regulation of binding GO:0051098 111 0.047
maintenance of protein location in cell GO:0032507 56 0.047
negative regulation of epithelial cell migration GO:0010633 38 0.046
wound healing spreading of cells GO:0044319 8 0.046
positive regulation of organelle organization GO:0010638 195 0.046
regulation of neuron differentiation GO:0045664 70 0.046
stem cell division GO:0017145 2 0.046

NEDD4L disease predictions

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 11 1.000
kidney disease DOID:557 36 1.000
urinary system disease DOID:18 40 1.000
respiratory system disease DOID:1579 14 0.837
lower respiratory tract disease DOID:0050161 13 0.837
nervous system disease DOID:863 431 0.059
neuropathy DOID:870 52 0.059