Homo sapiens

42 known processes

NEK1

NIMA (never in mitosis gene a)-related kinase 1

(Aliases: DKFZp686D06121,NY-REN-55,DKFZp686K12169,MGC138800,SRPS2,KIAA1901)

NEK1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 63 0.485
cilium morphogenesis GO:0060271 75 0.482
glial cell migration GO:0008347 4 0.371
cardiovascular system development GO:0072358 262 0.311
sensory perception of smell GO:0007608 2 0.299
neural tube patterning GO:0021532 2 0.280
purine ribonucleoside catabolic process GO:0046130 398 0.215
cilium organization GO:0044782 68 0.203
purine nucleotide catabolic process GO:0006195 405 0.200
cell projection organization GO:0030030 252 0.187
ribonucleotide catabolic process GO:0009261 405 0.186
ribonucleoside monophosphate catabolic process GO:0009158 158 0.180
purine containing compound catabolic process GO:0072523 411 0.164
organophosphate catabolic process GO:0046434 430 0.160
regulation of wnt signaling pathway GO:0030111 123 0.150
positive regulation of cellular component organization GO:0051130 376 0.144
replication fork processing GO:0031297 13 0.141
purine nucleoside triphosphate metabolic process GO:0009144 412 0.138
anterograde axon cargo transport GO:0008089 1 0.137
epithelium development GO:0060429 227 0.137
determination of adult lifespan GO:0008340 2 0.136
cellular response to dna damage stimulus GO:0006974 379 0.131
Mouse
dna conformation change GO:0071103 113 0.130
cell projection morphogenesis GO:0048858 129 0.130
ribonucleoside triphosphate metabolic process GO:0009199 412 0.125
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.121
cell development GO:0048468 328 0.116
wnt signaling pathway GO:0016055 156 0.116
organelle fission GO:0048285 149 0.112
nucleoside catabolic process GO:0009164 408 0.109
organelle assembly GO:0070925 176 0.109
glycosyl compound catabolic process GO:1901658 413 0.105
purine nucleoside monophosphate metabolic process GO:0009126 186 0.102
purine nucleoside triphosphate catabolic process GO:0009146 392 0.101
neuron differentiation GO:0030182 138 0.100
neuron projection development GO:0031175 106 0.100
purine nucleoside monophosphate catabolic process GO:0009128 158 0.100
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.099
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.095
chemotaxis GO:0006935 157 0.094
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.092
cellular component morphogenesis GO:0032989 314 0.090
nervous system development GO:0007399 293 0.083
mitotic cell cycle GO:0000278 326 0.081
nucleoside phosphate catabolic process GO:1901292 412 0.077
cellular component assembly involved in morphogenesis GO:0010927 73 0.077
taxis GO:0042330 157 0.077
generation of neurons GO:0048699 152 0.076
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.076
negative regulation of protein metabolic process GO:0051248 391 0.076
regulation of cell cycle GO:0051726 393 0.075
anatomical structure formation involved in morphogenesis GO:0048646 284 0.075
ribonucleoside monophosphate metabolic process GO:0009161 187 0.074
regulation of cell differentiation GO:0045595 393 0.074
tube development GO:0035295 125 0.074
cell morphogenesis GO:0000902 296 0.073
system process GO:0003008 349 0.072
microtubule cytoskeleton organization GO:0000226 176 0.070
axon cargo transport GO:0008088 2 0.069
purine nucleoside catabolic process GO:0006152 398 0.068
nucleoside triphosphate catabolic process GO:0009143 394 0.068
microtubule based process GO:0007017 210 0.067
neurogenesis GO:0022008 169 0.067
nucleotide catabolic process GO:0009166 408 0.065
female gamete generation GO:0007292 2 0.064
regulation of protein maturation GO:1903317 150 0.064
mitotic nuclear division GO:0007067 119 0.061
chromatin assembly GO:0031497 61 0.059
dna replication GO:0006260 116 0.057
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.055
ribonucleoside catabolic process GO:0042454 406 0.055
regulation of cell cycle process GO:0010564 266 0.054
dna dependent dna replication GO:0006261 44 0.054
cell projection assembly GO:0030031 126 0.053
neuron development GO:0048666 113 0.052
cell part morphogenesis GO:0032990 137 0.052
circulatory system development GO:0072359 262 0.052
cellular macromolecule catabolic process GO:0044265 380 0.051
inorganic cation transmembrane transport GO:0098662 194 0.051
positive regulation of cell cycle GO:0045787 140 0.050
regulation of meiotic cell cycle GO:0051445 4 0.050
microtubule based movement GO:0007018 32 0.050
cell morphogenesis involved in differentiation GO:0000904 144 0.049
nucleoside monophosphate metabolic process GO:0009123 191 0.049
cranial nerve development GO:0021545 4 0.048
negative regulation of developmental process GO:0051093 247 0.047
atp catabolic process GO:0006200 157 0.047
regulation of transporter activity GO:0032409 82 0.047
sodium ion transport GO:0006814 61 0.046
purine ribonucleotide catabolic process GO:0009154 404 0.046
ion homeostasis GO:0050801 230 0.043
positive regulation of organelle organization GO:0010638 195 0.043
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.042
positive regulation of cell cycle process GO:0090068 106 0.042
regulation of protein localization GO:0032880 296 0.042
anatomical structure homeostasis GO:0060249 100 0.041
nucleoside triphosphate metabolic process GO:0009141 422 0.041
chromatin modification GO:0016568 298 0.041
telomere maintenance GO:0000723 32 0.040
memory GO:0007613 3 0.040
chemical homeostasis GO:0048878 306 0.040
sodium ion transmembrane transport GO:0035725 59 0.040
positive regulation of telomere maintenance GO:0032206 4 0.040
regulation of ion transmembrane transport GO:0034765 132 0.039
atp metabolic process GO:0046034 176 0.038
regulation of epithelial cell proliferation GO:0050678 113 0.038
nuclear export GO:0051168 69 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
inner ear morphogenesis GO:0042472 4 0.036
positive regulation of wnt signaling pathway GO:0030177 54 0.036
regulation of proteolysis GO:0030162 293 0.036
nucleosome assembly GO:0006334 50 0.035
protein maturation GO:0051604 233 0.035
oogenesis GO:0048477 2 0.034
inner ear development GO:0048839 8 0.034
regulation of mapk cascade GO:0043408 262 0.033
regulation of intracellular transport GO:0032386 195 0.033
mitotic cell cycle process GO:1903047 286 0.033
ubiquitin dependent protein catabolic process GO:0006511 206 0.033
dna repair GO:0006281 198 0.032
nucleosome organization GO:0034728 66 0.032
nerve development GO:0021675 4 0.032
central nervous system development GO:0007417 123 0.032
cellular response to nitrogen compound GO:1901699 144 0.032
regulation of establishment of protein localization GO:0070201 242 0.032
regulation of intracellular protein transport GO:0033157 123 0.032
positive regulation of meiotic cell cycle GO:0051446 2 0.032
transmembrane transport GO:0055085 399 0.032
positive regulation of epithelial cell proliferation GO:0050679 65 0.032
sensory perception of sound GO:0007605 37 0.032
multicellular organismal aging GO:0010259 3 0.031
segmentation GO:0035282 4 0.031
cation transmembrane transport GO:0098655 238 0.031
kidney development GO:0001822 53 0.031
embryo development GO:0009790 123 0.031
metal ion transport GO:0030001 272 0.031
regulation of homeostatic process GO:0032844 121 0.030
pattern specification process GO:0007389 43 0.030
mapk cascade GO:0000165 288 0.030
head development GO:0060322 108 0.030
cytoskeleton dependent intracellular transport GO:0030705 21 0.029
cellular amino acid metabolic process GO:0006520 116 0.029
cell division GO:0051301 168 0.029
modification dependent macromolecule catabolic process GO:0043632 212 0.029
neuromuscular junction development GO:0007528 3 0.029
neurological system process GO:0050877 163 0.029
tissue morphogenesis GO:0048729 96 0.029
regulation of protein catabolic process GO:0042176 155 0.029
regulation of dna metabolic process GO:0051052 153 0.028
microtubule based transport GO:0010970 21 0.028
positive regulation of developmental process GO:0051094 314 0.028
nucleoside monophosphate catabolic process GO:0009125 159 0.028
response to nitrogen compound GO:1901698 184 0.028
negative regulation of protein processing GO:0010955 142 0.028
positive regulation of transport GO:0051050 336 0.027
renal system development GO:0072001 63 0.027
negative regulation of multicellular organismal process GO:0051241 317 0.027
epithelial cell differentiation GO:0030855 141 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
double strand break repair GO:0006302 101 0.026
regulation of cellular protein catabolic process GO:1903362 96 0.026
dephosphorylation GO:0016311 209 0.026
sensory perception of mechanical stimulus GO:0050954 37 0.026
spindle organization GO:0007051 53 0.026
ras protein signal transduction GO:0007265 73 0.026
protein processing GO:0016485 226 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.026
canonical wnt signaling pathway GO:0060070 116 0.025
protein modification by small protein conjugation GO:0032446 342 0.025
epithelial cell proliferation GO:0050673 128 0.025
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.025
regulation of cell morphogenesis GO:0022604 153 0.025
spermatid differentiation GO:0048515 4 0.025
regulation of vesicle mediated transport GO:0060627 130 0.025
meiosis i GO:0007127 4 0.025
sensory perception of chemical stimulus GO:0007606 38 0.025
nitrogen compound transport GO:0071705 191 0.024
smoothened signaling pathway GO:0007224 14 0.024
regulation of receptor mediated endocytosis GO:0048259 32 0.024
intrinsic apoptotic signaling pathway GO:0097193 127 0.024
regulation of endocytosis GO:0030100 72 0.024
response to oxygen containing compound GO:1901700 369 0.024
chromatin remodeling GO:0006338 55 0.024
cation transport GO:0006812 331 0.024
hindbrain development GO:0030902 3 0.024
negative regulation of cell cycle GO:0045786 193 0.024
chromosome segregation GO:0007059 114 0.024
protein ubiquitination GO:0016567 314 0.023
regulation of protein transport GO:0051223 213 0.023
axon development GO:0061564 34 0.023
sensory perception GO:0007600 103 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
regulation of metal ion transport GO:0010959 120 0.023
apoptotic signaling pathway GO:0097190 268 0.023
meiotic chromosome segregation GO:0045132 4 0.023
dna packaging GO:0006323 77 0.023
blastoderm segmentation GO:0007350 2 0.023
ion transmembrane transport GO:0034220 338 0.023
negative regulation of mitotic cell cycle GO:0045930 102 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
regulation of transferase activity GO:0051338 355 0.023
positive regulation of transferase activity GO:0051347 227 0.022
membrane organization GO:0061024 292 0.022
protein dephosphorylation GO:0006470 81 0.022
rna splicing GO:0008380 131 0.022
dna replication independent nucleosome assembly GO:0006336 27 0.022
post embryonic development GO:0009791 2 0.022
sensory organ development GO:0007423 52 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
single organismal cell cell adhesion GO:0016337 148 0.022
nuclear division GO:0000280 128 0.022
regulation of ion homeostasis GO:2000021 73 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
mitotic cell cycle phase transition GO:0044772 162 0.022
dna replication independent nucleosome organization GO:0034724 27 0.021
regulation of transmembrane transporter activity GO:0022898 74 0.021
nuclear transport GO:0051169 179 0.021
reactive oxygen species biosynthetic process GO:1903409 4 0.021
regulation of membrane potential GO:0042391 95 0.021
regulation of cell cycle phase transition GO:1901987 126 0.020
regulation of chromosome organization GO:0033044 103 0.020
motor neuron axon guidance GO:0008045 2 0.020
forebrain development GO:0030900 26 0.020
cellular amine metabolic process GO:0044106 41 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
maintenance of location GO:0051235 112 0.020
morphogenesis of embryonic epithelium GO:0016331 4 0.020
positive regulation of dna metabolic process GO:0051054 73 0.020
vesicle mediated transport GO:0016192 371 0.020
amine metabolic process GO:0009308 44 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
regulation of kinase activity GO:0043549 314 0.019
protein catabolic process GO:0030163 325 0.019
regulation of cell projection organization GO:0031344 107 0.019
heart development GO:0007507 95 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
single organism cell adhesion GO:0098602 179 0.019
single organism membrane organization GO:0044802 268 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
spindle assembly involved in mitosis GO:0090307 12 0.019
regulation of cellular component biogenesis GO:0044087 281 0.018
cellular protein catabolic process GO:0044257 261 0.018
positive regulation of chromosome organization GO:2001252 41 0.018
skin development GO:0043588 76 0.018
double strand break repair via homologous recombination GO:0000724 50 0.018
endocytosis GO:0006897 159 0.018
chordate embryonic development GO:0043009 34 0.018
vasculature development GO:0001944 181 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
neuron projection morphogenesis GO:0048812 50 0.018
morphogenesis of an epithelium GO:0002009 60 0.018
negative regulation of proteolysis GO:0045861 132 0.018
positive regulation of dna replication GO:0045740 35 0.018
negative regulation of wnt signaling pathway GO:0030178 69 0.018
positive regulation of cell proliferation GO:0008284 301 0.017
mitochondrion organization GO:0007005 156 0.017
lipid metabolic process GO:0006629 381 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
regulation of cellular amine metabolic process GO:0033238 11 0.017
positive regulation of kinase activity GO:0033674 204 0.017
sequestering of calcium ion GO:0051208 17 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
action potential GO:0001508 34 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
regulation of jnk cascade GO:0046328 73 0.017
recombinational repair GO:0000725 50 0.017
monovalent inorganic cation transport GO:0015672 128 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
oocyte development GO:0048599 1 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
organelle localization GO:0051640 84 0.017
negative regulation of protein maturation GO:1903318 142 0.017
peptidyl tyrosine dephosphorylation GO:0035335 36 0.016
response to biotic stimulus GO:0009607 276 0.016
positive regulation of gtpase activity GO:0043547 166 0.016
establishment of protein localization to membrane GO:0090150 121 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
locomotory behavior GO:0007626 1 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
response to growth factor GO:0070848 205 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
regulation of sister chromatid segregation GO:0033045 27 0.016
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.016
cellular ketone metabolic process GO:0042180 80 0.016
protein dna complex assembly GO:0065004 64 0.016
negative regulation of cellular catabolic process GO:0031330 83 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
positive regulation of catabolic process GO:0009896 310 0.015
regulation of stress activated mapk cascade GO:0032872 84 0.015
cytoplasmic transport GO:0016482 379 0.015
regulation of rab gtpase activity GO:0032313 39 0.015
telomere organization GO:0032200 33 0.015
oocyte differentiation GO:0009994 2 0.015
axonogenesis GO:0007409 31 0.015
mitotic sister chromatid segregation GO:0000070 53 0.015
protein polyubiquitination GO:0000209 110 0.015
rna processing GO:0006396 255 0.015
regulation of dna replication GO:0006275 68 0.015
mitotic sister chromatid separation GO:0051306 18 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
nucleocytoplasmic transport GO:0006913 176 0.014
specification of symmetry GO:0009799 16 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
short term memory GO:0007614 1 0.014
dna duplex unwinding GO:0032508 30 0.014
dna geometric change GO:0032392 32 0.014
regulation of action potential GO:0098900 2 0.014
protein export from nucleus GO:0006611 29 0.014
regulation of cellular component movement GO:0051270 334 0.014
cell adhesion GO:0007155 325 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
receptor mediated endocytosis GO:0006898 84 0.014
epidermis development GO:0008544 59 0.014
gtp catabolic process GO:0006184 237 0.014
single organism cellular localization GO:1902580 332 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.014
cerebellum development GO:0021549 2 0.014
regulation of sodium ion transmembrane transporter activity GO:2000649 17 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
sister chromatid cohesion GO:0007062 24 0.013
signal transduction in response to dna damage GO:0042770 57 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
regulation of growth GO:0040008 165 0.013
protein autophosphorylation GO:0046777 123 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
negative regulation of transport GO:0051051 176 0.013
multi organism cellular process GO:0044764 156 0.013
mitotic spindle elongation GO:0000022 4 0.013
positive regulation of homeostatic process GO:0032846 47 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
determination of bilateral symmetry GO:0009855 15 0.013
immune system development GO:0002520 195 0.013
jnk cascade GO:0007254 80 0.013
neural tube development GO:0021915 9 0.013
regulation of cell development GO:0060284 161 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
stem cell development GO:0048864 69 0.013
regeneration GO:0031099 4 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.013
response to inorganic substance GO:0010035 127 0.013
cell cycle phase transition GO:0044770 173 0.013
regulation of sodium ion transport GO:0002028 24 0.012
calcium ion homeostasis GO:0055074 122 0.012
blood vessel morphogenesis GO:0048514 162 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
sequestering of metal ion GO:0051238 24 0.012
growth GO:0040007 202 0.012
cellular calcium ion homeostasis GO:0006874 117 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
divalent inorganic cation transport GO:0072511 158 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
leukocyte activation GO:0045321 164 0.012
metaphase anaphase transition of cell cycle GO:0044784 21 0.012
actin cytoskeleton organization GO:0030036 207 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.012
neuron remodeling GO:0016322 2 0.012
intracellular protein transport GO:0006886 270 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.012
divalent metal ion transport GO:0070838 152 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
brain development GO:0007420 97 0.012
response to abiotic stimulus GO:0009628 336 0.012
Mouse
secretion by cell GO:0032940 226 0.012
regulation of protein processing GO:0070613 150 0.012
sister chromatid segregation GO:0000819 54 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
developmental process involved in reproduction GO:0003006 66 0.012
regulation of cellular response to stress GO:0080135 244 0.012
cell fate determination GO:0001709 3 0.012
negative regulation of organelle organization GO:0010639 126 0.012
translation GO:0006412 132 0.012
lipid localization GO:0010876 106 0.012
response to axon injury GO:0048678 1 0.012
positive regulation of endocytosis GO:0045807 42 0.012
cellular homeostasis GO:0019725 196 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
reproductive process GO:0022414 106 0.011
cell substrate adhesion GO:0031589 132 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
centrosome organization GO:0051297 58 0.011
oxidation reduction process GO:0055114 396 0.011
metencephalon development GO:0022037 2 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
response to other organism GO:0051707 261 0.011
humoral immune response GO:0006959 49 0.011
regionalization GO:0003002 29 0.011
establishment of organelle localization GO:0051656 59 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
membrane depolarization during action potential GO:0086010 10 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
associative learning GO:0008306 1 0.011
positive regulation of cell division GO:0051781 59 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.011
positive regulation of cellular amine metabolic process GO:0033240 7 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
defense response GO:0006952 315 0.011
response to external biotic stimulus GO:0043207 261 0.011
cell growth GO:0016049 160 0.011
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.010
cellular cation homeostasis GO:0030003 163 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.010
signal transduction by p53 class mediator GO:0072331 72 0.010
cellular chemical homeostasis GO:0055082 180 0.010
reciprocal meiotic recombination GO:0007131 4 0.010
dna recombination GO:0006310 77 0.010
positive regulation of cell development GO:0010720 92 0.010
innate immune response GO:0045087 178 0.010
protein homooligomerization GO:0051260 100 0.010
regulation of ion transmembrane transporter activity GO:0032412 72 0.010
protein localization to membrane GO:0072657 160 0.010
cytokine production GO:0001816 247 0.010
secretion GO:0046903 254 0.010

NEK1 disease predictions

Disease DO term ID Size Probability Func Analog Org
meckel syndrome DOID:0050778 11 0.281
sensory system disease DOID:0050155 203 0.059
eye and adnexa disease DOID:1492 150 0.059
nervous system disease DOID:863 431 0.059
joubert syndrome DOID:0050777 18 0.035
eye disease DOID:5614 149 0.033
retinal disease DOID:5679 118 0.030
immune system disease DOID:2914 155 0.024
disease of cellular proliferation DOID:14566 174 0.019
hematopoietic system disease DOID:74 100 0.016
cancer DOID:162 167 0.015
central nervous system disease DOID:331 186 0.014
neurodegenerative disease DOID:1289 102 0.014
disease of metabolism DOID:0014667 295 0.012