Homo sapiens

15 known processes

NEU1

sialidase 1 (lysosomal sialidase)

(Aliases: FLJ93471,NANH,NEU,SIAL1)

NEU1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vacuole organization GO:0007033 44 0.582
hexose catabolic process GO:0019320 7 0.252
chemical homeostasis GO:0048878 306 0.247
ion transmembrane transport GO:0034220 338 0.197
carbohydrate catabolic process GO:0016052 36 0.176
locomotory behavior GO:0007626 1 0.126
membrane lipid metabolic process GO:0006643 53 0.116
monosaccharide metabolic process GO:0005996 74 0.111
epithelium development GO:0060429 227 0.110
single organism carbohydrate metabolic process GO:0044723 193 0.107
cellular amide metabolic process GO:0043603 69 0.098
ion homeostasis GO:0050801 230 0.097
hexose metabolic process GO:0019318 55 0.097
peripheral nervous system development GO:0007422 2 0.091
cellular amine metabolic process GO:0044106 41 0.087
cell development GO:0048468 328 0.079
galactose metabolic process GO:0006012 4 0.078
cellular ion homeostasis GO:0006873 168 0.077
carbohydrate metabolic process GO:0005975 207 0.075
reactive oxygen species metabolic process GO:0072593 75 0.063
inorganic ion transmembrane transport GO:0098660 231 0.061
lipid catabolic process GO:0016042 84 0.060
regulation of cellular amino acid metabolic process GO:0006521 6 0.059
divalent metal ion transport GO:0070838 152 0.055
mating GO:0007618 1 0.054
reactive nitrogen species metabolic process GO:2001057 3 0.054
system process GO:0003008 349 0.051
single organism carbohydrate catabolic process GO:0044724 33 0.050
exocytosis GO:0006887 71 0.049
determination of adult lifespan GO:0008340 2 0.048
cellular macromolecule catabolic process GO:0044265 380 0.046
myeloid cell differentiation GO:0030099 117 0.045
secretion by cell GO:0032940 226 0.045
apoptotic signaling pathway GO:0097190 268 0.043
cell morphogenesis GO:0000902 296 0.043
positive regulation of secretion GO:0051047 116 0.042
nephric duct development GO:0072176 4 0.042
proteasomal protein catabolic process GO:0010498 176 0.042
female gamete generation GO:0007292 2 0.041
negative regulation of programmed cell death GO:0043069 321 0.040
monovalent inorganic cation transport GO:0015672 128 0.039
positive regulation of secretion by cell GO:1903532 108 0.039
regulation of peptidase activity GO:0052547 180 0.039
response to biotic stimulus GO:0009607 276 0.039
protein localization to organelle GO:0033365 280 0.037
lipid metabolic process GO:0006629 381 0.037
inorganic cation transmembrane transport GO:0098662 194 0.036
cellular lipid metabolic process GO:0044255 303 0.036
protein maturation GO:0051604 233 0.036
neurological system process GO:0050877 163 0.035
regulation of transferase activity GO:0051338 355 0.035
cation transmembrane transport GO:0098655 238 0.035
protein catabolic process GO:0030163 325 0.034
anatomical structure formation involved in morphogenesis GO:0048646 284 0.034
negative regulation of apoptotic process GO:0043066 316 0.033
maintenance of location GO:0051235 112 0.033
cation transport GO:0006812 331 0.033
nervous system development GO:0007399 293 0.033
blastocyst development GO:0001824 3 0.033
pigment granule organization GO:0048753 7 0.032
positive regulation of phosphorylation GO:0042327 394 0.030
amine metabolic process GO:0009308 44 0.030
cellular ketone metabolic process GO:0042180 80 0.030
melanosome organization GO:0032438 7 0.030
cellular organohalogen metabolic process GO:0090345 2 0.030
post embryonic development GO:0009791 2 0.030
purinergic nucleotide receptor signaling pathway GO:0035590 4 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
negative regulation of cellular amine metabolic process GO:0033239 3 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.029
regulation of mapk cascade GO:0043408 262 0.028
cellular amino acid metabolic process GO:0006520 116 0.028
regulation of cellular ketone metabolic process GO:0010565 50 0.028
peptidyl lysine modification GO:0018205 144 0.028
negative regulation of cell death GO:0060548 345 0.027
transmembrane transport GO:0055085 399 0.027
regulation of secretion by cell GO:1903530 177 0.027
positive regulation of immune system process GO:0002684 283 0.027
oogenesis GO:0048477 2 0.026
modification dependent protein catabolic process GO:0019941 209 0.026
cell projection organization GO:0030030 252 0.026
regulation of protein kinase activity GO:0045859 289 0.025
positive regulation of developmental process GO:0051094 314 0.025
secretion GO:0046903 254 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
cellular component morphogenesis GO:0032989 314 0.024
response to oxygen containing compound GO:1901700 369 0.024
cytoplasmic transport GO:0016482 379 0.023
regulation of exocytosis GO:0017157 46 0.023
metal ion transport GO:0030001 272 0.023
sensory perception of pain GO:0019233 4 0.023
regulation of secretion GO:0051046 194 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
vesicle mediated transport GO:0016192 371 0.023
reactive oxygen species biosynthetic process GO:1903409 4 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
modification dependent macromolecule catabolic process GO:0043632 212 0.022
cellular lipid catabolic process GO:0044242 65 0.022
response to fungus GO:0009620 4 0.022
cellular homeostasis GO:0019725 196 0.022
cellular chemical homeostasis GO:0055082 180 0.022
cellular pigmentation GO:0033059 17 0.022
hair cell differentiation GO:0035315 2 0.022
response to nitrogen compound GO:1901698 184 0.022
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
oxidation reduction process GO:0055114 396 0.021
positive regulation of transport GO:0051050 336 0.021
growth GO:0040007 202 0.021
purine nucleoside monophosphate metabolic process GO:0009126 186 0.021
regulation of angiotensin levels in blood GO:0002002 3 0.021
regulation of wnt signaling pathway GO:0030111 123 0.020
lipid storage GO:0019915 28 0.020
regulation of lipid metabolic process GO:0019216 96 0.020
positive regulation of bone resorption GO:0045780 2 0.020
defense response GO:0006952 315 0.020
cellular protein catabolic process GO:0044257 261 0.020
positive regulation of exocytosis GO:0045921 35 0.020
lipid localization GO:0010876 106 0.020
protein oligomerization GO:0051259 173 0.019
generation of neurons GO:0048699 152 0.019
response to other organism GO:0051707 261 0.019
eye development GO:0001654 42 0.019
vesicle organization GO:0016050 62 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
neurogenesis GO:0022008 169 0.019
response to oxidative stress GO:0006979 121 0.019
hemopoiesis GO:0030097 180 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
neuronal action potential GO:0019228 9 0.018
lytic vacuole organization GO:0080171 24 0.018
regulation of protein maturation GO:1903317 150 0.018
sphingolipid metabolic process GO:0006665 38 0.018
cilium organization GO:0044782 68 0.018
cation homeostasis GO:0055080 189 0.018
neuron differentiation GO:0030182 138 0.018
central nervous system development GO:0007417 123 0.018
signal transduction by phosphorylation GO:0023014 297 0.017
glycolipid metabolic process GO:0006664 27 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.017
regulation of osteoblast differentiation GO:0045667 38 0.017
regulation of cellular response to stress GO:0080135 244 0.017
atp metabolic process GO:0046034 176 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.017
cranial nerve development GO:0021545 4 0.017
regulation of lymphocyte mediated immunity GO:0002706 33 0.017
single organism membrane organization GO:0044802 268 0.016
memory GO:0007613 3 0.016
negative regulation of oxidative stress induced cell death GO:1903202 17 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
long term memory GO:0007616 2 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
embryo development GO:0009790 123 0.016
regulation of kinase activity GO:0043549 314 0.016
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
regulation of systemic arterial blood pressure by hormone GO:0001990 12 0.016
divalent inorganic cation transport GO:0072511 158 0.016
regulation of homeostatic process GO:0032844 121 0.016
wnt signaling pathway GO:0016055 156 0.015
regulation of cell development GO:0060284 161 0.015
multicellular organismal aging GO:0010259 3 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
tissue homeostasis GO:0001894 63 0.015
protein acylation GO:0043543 138 0.015
cellular cation homeostasis GO:0030003 163 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.015
response to external biotic stimulus GO:0043207 261 0.015
microtubule based process GO:0007017 210 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
intracellular protein transport GO:0006886 270 0.015
regulation of defense response GO:0031347 154 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
compound eye development GO:0048749 1 0.014
positive regulation of smoothened signaling pathway GO:0045880 4 0.014
ph reduction GO:0045851 11 0.014
response to endoplasmic reticulum stress GO:0034976 49 0.014
ganglioside catabolic process GO:0006689 3 0.014
autophagy GO:0006914 88 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
nerve development GO:0021675 4 0.014
sulfur compound metabolic process GO:0006790 101 0.014
establishment of organelle localization GO:0051656 59 0.014
regulation of vesicle mediated transport GO:0060627 130 0.013
negative regulation of protein modification process GO:0031400 200 0.013
immune response GO:0006955 307 0.013
endochondral bone morphogenesis GO:0060350 3 0.013
cellular response to reactive oxygen species GO:0034614 50 0.013
metal ion homeostasis GO:0055065 169 0.013
membrane organization GO:0061024 292 0.013
protein ubiquitination GO:0016567 314 0.013
renal system development GO:0072001 63 0.013
regulation of hormone levels GO:0010817 125 0.013
protein autophosphorylation GO:0046777 123 0.013
regulation of postsynaptic membrane potential GO:0060078 1 0.013
circulatory system development GO:0072359 262 0.013
monovalent inorganic cation homeostasis GO:0055067 37 0.013
mapk cascade GO:0000165 288 0.013
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.013
regulation of cellular response to oxidative stress GO:1900407 26 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
response to axon injury GO:0048678 1 0.012
organophosphate catabolic process GO:0046434 430 0.012
regulation of cell differentiation GO:0045595 393 0.012
organelle assembly GO:0070925 176 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
positive regulation of cell death GO:0010942 263 0.012
lymphocyte activation GO:0046649 133 0.012
single organism reproductive process GO:0044702 98 0.012
cell projection assembly GO:0030031 126 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
lysosome organization GO:0007040 24 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.012
kidney development GO:0001822 53 0.012
aging GO:0007568 66 0.012
ossification GO:0001503 121 0.012
nucleoside catabolic process GO:0009164 408 0.012
protein acetylation GO:0006473 116 0.012
cell growth GO:0016049 160 0.011
histone modification GO:0016570 251 0.011
response to reactive oxygen species GO:0000302 61 0.011
neuromuscular junction development GO:0007528 3 0.011
positive regulation of defense response GO:0031349 87 0.011
calcium ion transport GO:0006816 147 0.011
epithelial cell proliferation GO:0050673 128 0.011
negative regulation of protein processing GO:0010955 142 0.011
reproductive process GO:0022414 106 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
chromatin organization GO:0006325 351 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
negative regulation of proteolysis GO:0045861 132 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
prostate gland development GO:0030850 3 0.011
regulation of intracellular transport GO:0032386 195 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.011
decidualization GO:0046697 4 0.011
response to organonitrogen compound GO:0010243 156 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
mitotic cell cycle GO:0000278 326 0.010
response to hormone GO:0009725 175 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
multicellular organismal signaling GO:0035637 34 0.010
cellular calcium ion homeostasis GO:0006874 117 0.010
dephosphorylation GO:0016311 209 0.010
pigmentation GO:0043473 22 0.010
osteoblast differentiation GO:0001649 92 0.010
negative regulation of transferase activity GO:0051348 124 0.010
negative regulation of peptidase activity GO:0010466 91 0.010

NEU1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.997
lysosomal storage disease DOID:3211 47 0.997
inherited metabolic disorder DOID:655 242 0.997
lipid storage disease DOID:9455 28 0.991
central nervous system disease DOID:331 186 0.886
nervous system disease DOID:863 431 0.886
cerebral degeneration DOID:1443 16 0.823
brain disease DOID:936 73 0.823
sphingolipidosis DOID:1927 14 0.731
mucopolysaccharidosis DOID:12798 11 0.393
neuronal ceroid lipofuscinosis DOID:14503 11 0.339
neurodegenerative disease DOID:1289 102 0.021
disease of cellular proliferation DOID:14566 174 0.016
sensory system disease DOID:0050155 203 0.011
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011
immune system disease DOID:2914 155 0.011
cancer DOID:162 167 0.011