|
|
amide biosynthetic process
|
GO:0043604 |
15 |
1.000
|
Fly |
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
1.000
|
Human |
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
9 |
1.000
|
Human |
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
8 |
1.000
|
Human |
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
1.000
|
Fly |
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
1 |
1.000
|
Fly |
|
|
vitamin d metabolic process
|
GO:0042359 |
10 |
1.000
|
Human |
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
1.000
|
Fly |
|
|
negative regulation of interleukin 8 biosynthetic process
|
GO:0045415 |
3 |
1.000
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
1.000
|
Human |
|
|
negative regulation of vitamin metabolic process
|
GO:0046137 |
6 |
1.000
|
Human |
|
|
activation of innate immune response
|
GO:0002218 |
55 |
1.000
|
Human |
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
1.000
|
Human |
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
5 |
1.000
|
Human |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.999
|
Human Fly |
|
|
positive regulation of mirna metabolic process
|
GO:2000630 |
4 |
0.999
|
Human |
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
4 |
0.999
|
Human |
|
|
positive regulation of cholesterol efflux
|
GO:0010875 |
8 |
0.999
|
|
|
|
cellular response to nicotine
|
GO:0071316 |
4 |
0.999
|
Human |
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.998
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.998
|
Human Fly |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.998
|
Human |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.997
|
Human |
|
|
positive regulation of hyaluronan biosynthetic process
|
GO:1900127 |
3 |
0.997
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.997
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.997
|
Human |
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
6 |
0.996
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.996
|
Human Fly |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.996
|
Human |
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
27 |
0.995
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.995
|
Human Fly |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.995
|
Human Fly |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.995
|
Human |
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.995
|
Fly |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.994
|
Human |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.994
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.993
|
Fly |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.993
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.992
|
Human |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.991
|
Human |
|
|
regulation of sterol transport
|
GO:0032371 |
21 |
0.991
|
|
|
|
antifungal humoral response
|
GO:0019732 |
2 |
0.990
|
Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.990
|
Human |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.990
|
Human |
|
|
regulation of mirna metabolic process
|
GO:2000628 |
5 |
0.990
|
Human |
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.989
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.987
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.986
|
Fly |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.986
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.985
|
Human |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.985
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.983
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.983
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.982
|
|
|
|
mirna metabolic process
|
GO:0010586 |
10 |
0.981
|
Human |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.980
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.980
|
Human |
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.980
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.979
|
|
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.978
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.978
|
Human |
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.976
|
Fly |
|
|
negative regulation of lipid storage
|
GO:0010888 |
11 |
0.976
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.975
|
Human Fly |
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.975
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.975
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.975
|
|
|
|
vitamin metabolic process
|
GO:0006766 |
26 |
0.974
|
Human |
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.974
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.973
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.973
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.971
|
Fly |
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.969
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.966
|
Human |
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.964
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.964
|
Fly |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.961
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.961
|
Human |
|
|
vitamin biosynthetic process
|
GO:0009110 |
11 |
0.961
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.960
|
Human Mouse Fly |
|
|
regulation of interleukin 8 biosynthetic process
|
GO:0045414 |
11 |
0.960
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.958
|
Human |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.957
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
1 |
0.957
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.956
|
Human Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.953
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.949
|
Human |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.949
|
Human |
|
|
activation of immune response
|
GO:0002253 |
114 |
0.949
|
Human |
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
12 |
0.949
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.947
|
Human Fly |
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.940
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.937
|
Human Fly |
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
20 |
0.935
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.934
|
Human |
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.928
|
Human |
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.926
|
Human Fly |
|
|
regulation of cholesterol transport
|
GO:0032374 |
21 |
0.926
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.925
|
Fly |
|
|
vitamin d biosynthetic process
|
GO:0042368 |
9 |
0.924
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.924
|
Human Fly |
|
|
type 2 immune response
|
GO:0042092 |
6 |
0.917
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.915
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.913
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.908
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.904
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.895
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.895
|
Human |
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.893
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.892
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.892
|
Human |
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.890
|
Human |
|
|
regulation of defense response to bacterium
|
GO:1900424 |
2 |
0.890
|
Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.884
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.879
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.878
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.877
|
Human |
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.876
|
Human |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.869
|
Fly |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.869
|
Human |
|
|
regulation of humoral immune response
|
GO:0002920 |
11 |
0.868
|
Fly |
|
|
peptide transport
|
GO:0015833 |
74 |
0.866
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.860
|
Human |
|
|
negative regulation of oxidoreductase activity
|
GO:0051354 |
17 |
0.858
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.849
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
4 |
0.842
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.840
|
Fly |
|
|
cellular response to alkaloid
|
GO:0071312 |
11 |
0.838
|
Human |
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.835
|
|
|
|
cytoplasmic sequestering of nf kappab
|
GO:0007253 |
7 |
0.826
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.825
|
Fly |
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.823
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.816
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.814
|
|
|
|
negative regulation of vitamin d biosynthetic process
|
GO:0010957 |
5 |
0.814
|
Human |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.811
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.811
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.807
|
Human |
|
|
nik nf kappab signaling
|
GO:0038061 |
12 |
0.804
|
Mouse |
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.801
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.795
|
Human |
|
|
aminoglycan metabolic process
|
GO:0006022 |
39 |
0.793
|
Human |
|
|
t helper 1 cell differentiation
|
GO:0045063 |
1 |
0.793
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.792
|
Human |
|
|
immune effector process
|
GO:0002252 |
159 |
0.792
|
Fly |
|
|
sterol transport
|
GO:0015918 |
39 |
0.789
|
|
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
21 |
0.785
|
Human |
|
|
t helper 1 type immune response
|
GO:0042088 |
8 |
0.783
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.780
|
Fly |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.774
|
Human Fly |
|
|
regulation of cholesterol efflux
|
GO:0010874 |
11 |
0.774
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.772
|
Fly |
|
|
defense response to virus
|
GO:0051607 |
71 |
0.772
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.771
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.769
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.763
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.753
|
Human Fly |
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.753
|
Human |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.750
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.750
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.748
|
Human |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.746
|
Human |
|
|
negative regulation of alcohol biosynthetic process
|
GO:1902931 |
13 |
0.742
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.740
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.738
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.735
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.732
|
Human |
|
|
positive regulation of translation
|
GO:0045727 |
35 |
0.731
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.730
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.727
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.725
|
Human Fly |
|
|
hyaluronan metabolic process
|
GO:0030212 |
15 |
0.720
|
Human |
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.718
|
Human |
|
|
dorsal ventral axis specification
|
GO:0009950 |
7 |
0.718
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.717
|
Mouse |
|
|
nervous system development
|
GO:0007399 |
293 |
0.717
|
Fly |
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.717
|
Human |
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.708
|
Fly |
|
|
interleukin 8 biosynthetic process
|
GO:0042228 |
12 |
0.702
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.701
|
Human |
|
|
response to exogenous dsrna
|
GO:0043330 |
10 |
0.701
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.700
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.699
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.694
|
|
|
|
response to uv b
|
GO:0010224 |
10 |
0.691
|
Human |
|
|
myeloid dendritic cell activation
|
GO:0001773 |
4 |
0.683
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.681
|
Fly |
|
|
macrophage derived foam cell differentiation
|
GO:0010742 |
15 |
0.675
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.669
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.667
|
Fly |
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.667
|
Human |
|
|
aminoglycan biosynthetic process
|
GO:0006023 |
29 |
0.666
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.656
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.653
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.652
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
3 |
0.648
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.642
|
Fly |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.637
|
Human |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.637
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.636
|
Human |
|
|
hyaluronan biosynthetic process
|
GO:0030213 |
10 |
0.629
|
Human |
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.628
|
Human |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.625
|
Human |
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.624
|
Human |
|
|
regulation of lipid storage
|
GO:0010883 |
21 |
0.624
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.612
|
Human |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.607
|
|
|
|
regulation of interleukin 12 biosynthetic process
|
GO:0045075 |
1 |
0.605
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.602
|
Mouse |
|
|
positive regulation of cholesterol transport
|
GO:0032376 |
10 |
0.594
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.589
|
Human |
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.579
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.575
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
20 |
0.560
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.558
|
|
|
|
response to nicotine
|
GO:0035094 |
12 |
0.557
|
Human |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.542
|
Human |
|
|
protein import
|
GO:0017038 |
130 |
0.533
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.532
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
25 |
0.531
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.519
|
Fly |
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.517
|
Mouse |
|
|
negative regulation of macrophage derived foam cell differentiation
|
GO:0010745 |
7 |
0.514
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.513
|
Human |
|
|
regulation of interleukin 12 production
|
GO:0032655 |
15 |
0.513
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.510
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
4 |
0.507
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.506
|
Fly |
|
|
lipid localization
|
GO:0010876 |
106 |
0.498
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.490
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.489
|
Human |
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.483
|
Human |
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
35 |
0.479
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.474
|
Human |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.473
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
22 |
0.468
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.462
|
Human |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.458
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.452
|
Human |
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.446
|
Fly |
|
|
peptide biosynthetic process
|
GO:0043043 |
8 |
0.444
|
Fly |
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.440
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
1 |
0.435
|
|
|
|
interleukin 12 production
|
GO:0032615 |
15 |
0.434
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.427
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
20 |
0.427
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.423
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.416
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.406
|
Human |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
5 |
0.397
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.390
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.390
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.388
|
Human |
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.382
|
|
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
11 |
0.375
|
Human |
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
27 |
0.365
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.357
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.356
|
Human |
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
7 |
0.355
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
12 |
0.353
|
Human |
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
18 |
0.346
|
Fly |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.341
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
24 |
0.341
|
Fly |
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.340
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.337
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.336
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.332
|
Human Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.326
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
10 |
0.323
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.310
|
Human |
|
|
glycosaminoglycan biosynthetic process
|
GO:0006024 |
27 |
0.301
|
Human |
|
|
negative regulation of monooxygenase activity
|
GO:0032769 |
7 |
0.301
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.300
|
|
|
|
regulation of interferon alpha production
|
GO:0032647 |
11 |
0.300
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.300
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.294
|
Human |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.291
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.279
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.279
|
Human |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.278
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.276
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.264
|
Human |
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.264
|
|
|
|
regulation of macrophage derived foam cell differentiation
|
GO:0010743 |
14 |
0.261
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.260
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.258
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.255
|
Human |
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.249
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.247
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.246
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
17 |
0.246
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.237
|
Human |
|
|
response to dsrna
|
GO:0043331 |
25 |
0.235
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.233
|
|
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
9 |
0.232
|
Fly |
|
|
protein targeting
|
GO:0006605 |
187 |
0.231
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.225
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.225
|
|
|
|
translation
|
GO:0006412 |
132 |
0.222
|
|
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.220
|
Human |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.216
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.214
|
|
|
|
response to interleukin 6
|
GO:0070741 |
15 |
0.209
|
Human |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.206
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.205
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.201
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.200
|
Fly |
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.194
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.191
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.187
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.180
|
Fly |
|
|
regulation of hyaluronan biosynthetic process
|
GO:1900125 |
6 |
0.177
|
Human |
|
|
lipid transport
|
GO:0006869 |
90 |
0.176
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.174
|
Human |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.173
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.171
|
Human |
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.166
|
Human |
|
|
positive regulation of sterol transport
|
GO:0032373 |
10 |
0.164
|
|
|
|
regulation of cardiac muscle cell membrane potential
|
GO:0086036 |
1 |
0.162
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.161
|
Human |
|
|
regulation of polysaccharide metabolic process
|
GO:0032881 |
21 |
0.159
|
Human |
|
|
epithelium development
|
GO:0060429 |
227 |
0.156
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.155
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.152
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.151
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.149
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.149
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.146
|
|
|
|
response to uv c
|
GO:0010225 |
7 |
0.146
|
|
|
|
regulation of calcidiol 1 monooxygenase activity
|
GO:0060558 |
6 |
0.142
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.135
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.135
|
Fly |
|
|
negative regulation of steroid metabolic process
|
GO:0045939 |
15 |
0.134
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.132
|
Human |
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.131
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.130
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.127
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.123
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.122
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.120
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.117
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.115
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
11 |
0.114
|
|
|
|
negative regulation of steroid biosynthetic process
|
GO:0010894 |
15 |
0.114
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.114
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.110
|
|
|
|
negative regulation of calcidiol 1 monooxygenase activity
|
GO:0010956 |
3 |
0.109
|
Human |
|
|
cellular response to glucose stimulus
|
GO:0071333 |
10 |
0.109
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.107
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
1 |
0.107
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.107
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.106
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.104
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.103
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
5 |
0.102
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.101
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.100
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.099
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.099
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.098
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.095
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.095
|
Fly |
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.094
|
|
|
|
regulation of cd40 signaling pathway
|
GO:2000348 |
3 |
0.093
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.091
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.090
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.090
|
Fly |
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
17 |
0.088
|
Fly |
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.088
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.088
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.087
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.086
|
Human |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.085
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.084
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.083
|
Fly |
|
|
neutral amino acid transport
|
GO:0015804 |
9 |
0.082
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.081
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.080
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.080
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.079
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.079
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.078
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.076
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.075
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.074
|
Human |
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.074
|
|
|
|
cholesterol efflux
|
GO:0033344 |
28 |
0.073
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.072
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.071
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
22 |
0.071
|
Fly |
|
|
organic anion transport
|
GO:0015711 |
103 |
0.070
|
|
|
|
acute phase response
|
GO:0006953 |
5 |
0.070
|
|
|
|
negative regulation of reactive oxygen species metabolic process
|
GO:2000378 |
11 |
0.070
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.068
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.068
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.068
|
|
|
|
positive regulation of interleukin 10 biosynthetic process
|
GO:0045082 |
1 |
0.067
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.066
|
|
|
|
i kappab phosphorylation
|
GO:0007252 |
7 |
0.064
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.064
|
Human |
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.064
|
|
|
|
cytoplasmic sequestering of transcription factor
|
GO:0042994 |
9 |
0.063
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.063
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.062
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.062
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.060
|
|
|
|
negative regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031665 |
7 |
0.060
|
|
|
|
serine phosphorylation of stat protein
|
GO:0042501 |
4 |
0.059
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.059
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.058
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.057
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.056
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.056
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.055
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.055
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.054
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.053
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.053
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.053
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.053
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.052
|
|
|
|
regulation of monooxygenase activity
|
GO:0032768 |
22 |
0.052
|
Human |
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.052
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
15 |
0.050
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
6 |
0.050
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.049
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
15 |
0.049
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.049
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.048
|
|
|
|
negative regulation of interleukin 1 beta production
|
GO:0032691 |
6 |
0.048
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.048
|
Fly |
|
|
memory
|
GO:0007613 |
3 |
0.048
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.048
|
Fly |
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.047
|
Human |
|
|
ossification
|
GO:0001503 |
121 |
0.047
|
|
|
|
negative regulation of nf kappab import into nucleus
|
GO:0042347 |
12 |
0.047
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.047
|
|
|
|
positive regulation of interleukin 13 production
|
GO:0032736 |
4 |
0.047
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.046
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
13 |
0.046
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.046
|
Human |
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.046
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.046
|
|
|
|
receptor mediated virion attachment to host cell
|
GO:0046813 |
4 |
0.045
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.044
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.044
|
|
|
|
regulation of ruffle assembly
|
GO:1900027 |
8 |
0.043
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.043
|
Fly |
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.043
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
27 |
0.041
|
Human |
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.041
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.041
|
|
|
|
toll like receptor 3 signaling pathway
|
GO:0034138 |
4 |
0.041
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.041
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.040
|
Fly |
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
12 |
0.040
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.039
|
Human |
|
|
regulation of interleukin 10 production
|
GO:0032653 |
16 |
0.039
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.039
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.038
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.038
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.038
|
Mouse |
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.038
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.037
|
|
|
|
foam cell differentiation
|
GO:0090077 |
15 |
0.037
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.036
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.036
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.036
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.036
|
Mouse |
|
|
nuclear import
|
GO:0051170 |
106 |
0.036
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.036
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.036
|
Fly |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.034
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.033
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.033
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.033
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.032
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.032
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
12 |
0.032
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.031
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.031
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.031
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.031
|
|
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.030
|
|
|
|
single organism carbohydrate catabolic process
|
GO:0044724 |
33 |
0.030
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.030
|
|
|
|
regulation of camp mediated signaling
|
GO:0043949 |
13 |
0.030
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
1 |
0.030
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.030
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.029
|
|
