|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.996
|
Fly |
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
1 |
0.986
|
Fly |
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.985
|
Fly |
|
|
negative regulation of interleukin 8 biosynthetic process
|
GO:0045415 |
3 |
0.952
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.942
|
Human |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.939
|
Human Rat |
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.931
|
Fly |
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
0.895
|
|
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
0.878
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
2 |
0.870
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.868
|
Human Rat |
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.851
|
Fly |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.840
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.810
|
|
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.803
|
Human |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.781
|
Fly |
|
|
cholesterol efflux
|
GO:0033344 |
28 |
0.757
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.727
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.704
|
Fly |
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.673
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.671
|
Fly |
|
|
antifungal humoral response
|
GO:0019732 |
2 |
0.667
|
Fly |
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.664
|
Human |
|
|
vitamin d metabolic process
|
GO:0042359 |
10 |
0.647
|
|
|
|
positive regulation of cholesterol efflux
|
GO:0010875 |
8 |
0.636
|
Human |
|
|
antibacterial humoral response
|
GO:0019731 |
24 |
0.627
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.624
|
|
|
|
serine phosphorylation of stat protein
|
GO:0042501 |
4 |
0.617
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.602
|
Human |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.591
|
Fly |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.590
|
Fly |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.579
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.572
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.562
|
Fly |
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
4 |
0.547
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.546
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.542
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
178 |
0.525
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.513
|
Fly |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.481
|
Fly |
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.481
|
|
|
|
negative regulation of lipid storage
|
GO:0010888 |
11 |
0.470
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.466
|
Human |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.459
|
|
|
|
positive regulation of hyaluronan biosynthetic process
|
GO:1900127 |
3 |
0.445
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.443
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.432
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.407
|
Fly |
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.405
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.398
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.394
|
Human Rat |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.383
|
Fly |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.377
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.372
|
Human |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.359
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.353
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.349
|
Fly |
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
8 |
0.346
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.332
|
Mouse |
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.325
|
Fly |
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
18 |
0.323
|
Fly |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.323
|
Mouse |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.319
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.318
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.307
|
Human |
|
|
regulation of sterol transport
|
GO:0032371 |
21 |
0.306
|
Human |
|
|
response to fungus
|
GO:0009620 |
4 |
0.304
|
Fly |
|
|
vitamin metabolic process
|
GO:0006766 |
26 |
0.295
|
|
|
|
negative regulation of vitamin metabolic process
|
GO:0046137 |
6 |
0.288
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.287
|
Human Mouse Fly |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.284
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.282
|
Fly |
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.280
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.279
|
Fly |
|
|
response to uv
|
GO:0009411 |
73 |
0.279
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.277
|
Mouse |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.275
|
Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
0.274
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.271
|
Human |
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.263
|
Human |
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
12 |
0.259
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.258
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
4 |
0.257
|
|
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
9 |
0.249
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.249
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.247
|
Fly |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.242
|
Human |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.241
|
Human Rat |
|
|
sterol transport
|
GO:0015918 |
39 |
0.236
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.235
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.227
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.222
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.222
|
Human Fly |
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.220
|
Fly |
|
|
immune effector process
|
GO:0002252 |
159 |
0.220
|
Fly |
|
|
regulation of cholesterol efflux
|
GO:0010874 |
11 |
0.199
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.196
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.195
|
Fly |
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.191
|
Fly |
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
9 |
0.174
|
Fly |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.170
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.167
|
Human Rat |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.162
|
Human |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.161
|
Human Rat |
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
6 |
0.160
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.159
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.157
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
1 |
0.157
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.156
|
Fly |
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.149
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.147
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.147
|
Human |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.147
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.141
|
Human Rat |
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
27 |
0.141
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
11 |
0.140
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.138
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.138
|
Human Mouse Fly |
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
20 |
0.131
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.129
|
Human |
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.122
|
Human Rat |
|
|
lipid transport
|
GO:0006869 |
90 |
0.119
|
Human |
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
5 |
0.117
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.115
|
|
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
11 |
0.115
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
12 |
0.111
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.111
|
Human |
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.109
|
Human |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.108
|
Human |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.108
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.108
|
Human Rat |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.107
|
Human Mouse Fly |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.106
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.105
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.104
|
Human |
|
|
foam cell differentiation
|
GO:0090077 |
15 |
0.102
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.100
|
Human Rat |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.100
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.099
|
Human |
|
|
positive regulation of interferon beta production
|
GO:0032728 |
17 |
0.099
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.098
|
|
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
21 |
0.098
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.096
|
Human Rat |
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.095
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.094
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.092
|
Human Rat |
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.092
|
Fly |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.090
|
|
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.089
|
Human Rat |
|
|
cellular response to nicotine
|
GO:0071316 |
4 |
0.089
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.088
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
27 |
0.087
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.087
|
Human Rat |
|
|
response to exogenous dsrna
|
GO:0043330 |
10 |
0.087
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.086
|
Fly |
|
|
organic anion transport
|
GO:0015711 |
103 |
0.086
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.085
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.085
|
Human Rat |
|
|
positive regulation of transcription during mitosis
|
GO:0045897 |
2 |
0.084
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.084
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.083
|
Fly |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.083
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.082
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.081
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.080
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.080
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.078
|
Human |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.077
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
8 |
0.077
|
Fly |
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.077
|
|
|
|
negative regulation of vitamin d biosynthetic process
|
GO:0010957 |
5 |
0.076
|
|
|
|
regulation of macrophage derived foam cell differentiation
|
GO:0010743 |
14 |
0.075
|
Human |
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.075
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.074
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.074
|
Human |
|
|
regulation of polysaccharide metabolic process
|
GO:0032881 |
21 |
0.074
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.074
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.073
|
|
|
|
regulation of monooxygenase activity
|
GO:0032768 |
22 |
0.073
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.073
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.072
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.072
|
Human Rat |
|
|
vitamin d biosynthetic process
|
GO:0042368 |
9 |
0.072
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.071
|
|
|
|
mirna metabolic process
|
GO:0010586 |
10 |
0.071
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.070
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.068
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.067
|
|
|
|
regulation of interleukin 8 biosynthetic process
|
GO:0045414 |
11 |
0.067
|
Human |
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
17 |
0.067
|
Human Rat |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.066
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.065
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.065
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
1 |
0.064
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.063
|
Human |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.063
|
Fly |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.063
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.061
|
Human Rat |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.061
|
|
|
|
spleen development
|
GO:0048536 |
1 |
0.061
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.060
|
Human Rat |
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
11 |
0.060
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.058
|
Human Rat |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.058
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.058
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
25 |
0.057
|
|
|
|
i kappab phosphorylation
|
GO:0007252 |
7 |
0.057
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.056
|
Mouse |
|
|
regulation of mirna metabolic process
|
GO:2000628 |
5 |
0.056
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.056
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.056
|
|
|
|
epiboly involved in gastrulation with mouth forming second
|
GO:0055113 |
1 |
0.056
|
|
|
|
negative regulation of calcidiol 1 monooxygenase activity
|
GO:0010956 |
3 |
0.056
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.056
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.055
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.055
|
Human Rat |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.054
|
|
|
|
regulation of transcription during mitosis
|
GO:0045896 |
2 |
0.054
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.054
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.053
|
Human |
|
|
lactation
|
GO:0007595 |
3 |
0.052
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.052
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.052
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.051
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.050
|
Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.050
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.050
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.050
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.049
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.049
|
|
|
|
regulation of hyaluronan biosynthetic process
|
GO:1900125 |
6 |
0.049
|
|
|
|
cellular response to alkaloid
|
GO:0071312 |
11 |
0.048
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.047
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.047
|
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.047
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.046
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.045
|
|
|
|
negative regulation of alcohol biosynthetic process
|
GO:1902931 |
13 |
0.045
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.045
|
Human Rat |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.044
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.044
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.043
|
Human Rat |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.043
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.043
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.042
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.042
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.042
|
Human Rat |
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.042
|
Human Rat |
|
|
translation
|
GO:0006412 |
132 |
0.042
|
Human |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.042
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.041
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.041
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.041
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.040
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.040
|
Human Rat |
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.039
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.039
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.039
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.038
|
Human Rat |
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.038
|
Human Rat |
|
|
aminoglycan metabolic process
|
GO:0006022 |
39 |
0.037
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.037
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.037
|
Human |
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.036
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.036
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.036
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.036
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.035
|
Human Rat |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.035
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.033
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.033
|
Human Rat |
|
|
aminoglycan biosynthetic process
|
GO:0006023 |
29 |
0.033
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.033
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.033
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.032
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.032
|
Human |
|
|
response to dsrna
|
GO:0043331 |
25 |
0.032
|
|
|
|
type 2 immune response
|
GO:0042092 |
6 |
0.032
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.032
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
12 |
0.031
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.031
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.031
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.031
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.031
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.031
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.030
|
Fly |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.030
|
Human |
|
|
regulation of interferon alpha production
|
GO:0032647 |
11 |
0.030
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.029
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.029
|
Human Rat |
|
|
immune system development
|
GO:0002520 |
195 |
0.029
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.029
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.029
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.029
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.029
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.029
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.029
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.028
|
Human |
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.028
|
Human |
|
|
gene silencing
|
GO:0016458 |
49 |
0.028
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.028
|
Human Rat |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.027
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.027
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.027
|
|
|
|
glycosaminoglycan biosynthetic process
|
GO:0006024 |
27 |
0.026
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.026
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.026
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.026
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
11 |
0.026
|
Human |
|
|
skeletal muscle contraction
|
GO:0003009 |
16 |
0.026
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.026
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.026
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.026
|
Human |
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
12 |
0.026
|
Human |
|
|
dorsal ventral axis specification
|
GO:0009950 |
7 |
0.025
|
Fly |
|
|
regulation of lipid storage
|
GO:0010883 |
21 |
0.025
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.024
|
Fly |
|
|
phagocytosis
|
GO:0006909 |
42 |
0.024
|
Fly |
|
|
cytoplasmic sequestering of transcription factor
|
GO:0042994 |
9 |
0.024
|
Human Rat |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.024
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.024
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.024
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.024
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.024
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.024
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.024
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.024
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.023
|
Human Rat |
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.023
|
|
|
|
response to uv c
|
GO:0010225 |
7 |
0.023
|
Human |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.023
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.023
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.023
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.023
|
Human Rat |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.023
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.023
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.023
|
Human Rat |
|
|
rhythmic process
|
GO:0048511 |
31 |
0.023
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.022
|
Human |
|
|
negative regulation of steroid biosynthetic process
|
GO:0010894 |
15 |
0.022
|
|
|
|
response to hexose
|
GO:0009746 |
20 |
0.022
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.022
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.022
|
Human Rat |
|
|
negative regulation of response to interferon gamma
|
GO:0060331 |
2 |
0.022
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
29 |
0.021
|
|
|
|
negative regulation of steroid metabolic process
|
GO:0045939 |
15 |
0.021
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.021
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.021
|
Human Rat |
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.021
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.021
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.021
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.021
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
16 |
0.021
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
17 |
0.021
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.020
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.020
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.020
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.020
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.020
|
Human |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.020
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.020
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.020
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.020
|
|
|
|
cytoplasmic sequestering of nf kappab
|
GO:0007253 |
7 |
0.020
|
Human Rat |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.020
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.020
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.020
|
Human Rat |
|
|
vitamin biosynthetic process
|
GO:0009110 |
11 |
0.020
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.020
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.020
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.020
|
Human Rat |
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.019
|
|
|
|
interleukin 8 biosynthetic process
|
GO:0042228 |
12 |
0.019
|
Human |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.019
|
|
|
|
response to fatty acid
|
GO:0070542 |
13 |
0.019
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.019
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.019
|
|
|
|
positive regulation of sterol transport
|
GO:0032373 |
10 |
0.019
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.019
|
Human Rat |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.019
|
Human |
|
|
neutrophil mediated immunity
|
GO:0002446 |
4 |
0.019
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.019
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.019
|
Human |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.019
|
|
|
|
musculoskeletal movement
|
GO:0050881 |
17 |
0.019
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.019
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.019
|
Fly |
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.018
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.018
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.018
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.018
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.018
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.018
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.018
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.018
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.018
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.018
|
Human Rat |
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.018
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.018
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.018
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.018
|
Human Rat |
|
|
dna conformation change
|
GO:0071103 |
113 |
0.018
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.018
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.018
|
|
|
|
type i interferon production
|
GO:0032606 |
27 |
0.018
|
|
|
|
positive regulation of anoikis
|
GO:2000210 |
4 |
0.018
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.018
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.017
|
|
|
|
interleukin 12 production
|
GO:0032615 |
15 |
0.017
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.017
|
|
|
|
regulation of type i interferon production
|
GO:0032479 |
26 |
0.017
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.017
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.017
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.017
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.017
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.017
|
Human Rat |
|
|
regulation of chromatin silencing
|
GO:0031935 |
8 |
0.017
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.017
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.017
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.017
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.017
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.017
|
Human Rat |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.016
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.016
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.016
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.016
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.016
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.016
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.016
|
|
|
|
somite development
|
GO:0061053 |
7 |
0.016
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.016
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.016
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.016
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.016
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.016
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.016
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.016
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.016
|
|
|
|
negative regulation of oxidoreductase activity
|
GO:0051354 |
17 |
0.016
|
|
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.016
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.016
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.016
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.015
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.015
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
35 |
0.015
|
|
|
|
peptidyl lysine monomethylation
|
GO:0018026 |
4 |
0.015
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.015
|
|
|
|
negative regulation of nf kappab import into nucleus
|
GO:0042347 |
12 |
0.015
|
Human Rat |
|
|
regulation of calcidiol 1 monooxygenase activity
|
GO:0060558 |
6 |
0.015
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.015
|
Mouse |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.015
|
|
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
3 |
0.015
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
12 |
0.015
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.014
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.014
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.014
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.014
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
1 |
0.014
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.014
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.014
|
|
|
|
regulation of double strand break repair via homologous recombination
|
GO:0010569 |
11 |
0.014
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.014
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.014
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.014
|
|
|
|
cellular aldehyde metabolic process
|
GO:0006081 |
20 |
0.014
|
|
|
|
positive regulation of cholesterol transport
|
GO:0032376 |
10 |
0.014
|
Human |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.014
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.014
|
|
|
|
multicellular organismal movement
|
GO:0050879 |
17 |
0.014
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.013
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.013
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.013
|
|
|
|
positive regulation of mirna metabolic process
|
GO:2000630 |
4 |
0.013
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.013
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.013
|
Human |
|
|
regulation of viral release from host cell
|
GO:1902186 |
20 |
0.013
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.013
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.013
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.013
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.013
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.013
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.013
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.013
|
Human Rat |
|
|
tissue migration
|
GO:0090130 |
119 |
0.013
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.013
|
|
