|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
11 |
1.000
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
12 |
1.000
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
21 |
0.996
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
1 |
0.994
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
15 |
0.994
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
18 |
0.993
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
22 |
0.991
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
2 |
0.986
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.980
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
13 |
0.979
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
18 |
0.978
|
|
|
|
positive regulation of interleukin 1 production
|
GO:0032732 |
14 |
0.954
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.906
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.904
|
|
|
|
protein autoprocessing
|
GO:0016540 |
4 |
0.902
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.892
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
2 |
0.884
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.870
|
|
|
|
interleukin 1 production
|
GO:0032612 |
26 |
0.852
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.832
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.821
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.805
|
Mouse |
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.804
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.802
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.789
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.781
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.781
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
11 |
0.765
|
|
|
|
midgut development
|
GO:0007494 |
1 |
0.747
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.739
|
|
|
|
pyroptosis
|
GO:0070269 |
1 |
0.729
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.723
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.717
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
1 |
0.707
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.696
|
Mouse |
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.682
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.681
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.680
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.677
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
1 |
0.641
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.632
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.632
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.629
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.628
|
Mouse |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.619
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.619
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.593
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
14 |
0.589
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.585
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.577
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.576
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.563
|
|
|
|
memory
|
GO:0007613 |
3 |
0.558
|
|
|
|
negative regulation of interferon beta production
|
GO:0032688 |
4 |
0.531
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.515
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.512
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.508
|
|
|
|
detection of muramyl dipeptide
|
GO:0032498 |
1 |
0.508
|
|
|
|
t cell migration
|
GO:0072678 |
16 |
0.507
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.502
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.498
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.487
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.486
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.483
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.480
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.477
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.475
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.468
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.450
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.442
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.441
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
21 |
0.440
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.437
|
Mouse |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.427
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.426
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.425
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.424
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.421
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.414
|
|
|
|
positive regulation of interleukin 10 secretion
|
GO:2001181 |
2 |
0.413
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.412
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.412
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.407
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.406
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.402
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.401
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
13 |
0.396
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.396
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.393
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.391
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.382
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
9 |
0.380
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.379
|
Mouse |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.372
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.370
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.368
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.367
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.366
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.364
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.364
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.360
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.349
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.345
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.341
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.340
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.337
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.331
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.329
|
|
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
0.328
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.327
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.326
|
Mouse |
|
|
spermatid development
|
GO:0007286 |
4 |
0.325
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.325
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.324
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
14 |
0.320
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.319
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.310
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.307
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.307
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.303
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.300
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.299
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.299
|
|
|
|
toxin transport
|
GO:1901998 |
4 |
0.299
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.297
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.291
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.290
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.289
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
2 |
0.285
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.284
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.284
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.280
|
|
|
|
positive regulation of interleukin 6 secretion
|
GO:2000778 |
6 |
0.278
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.277
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.277
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.275
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.274
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.274
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.274
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.274
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.268
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.267
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.267
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.260
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.260
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.260
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.259
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.257
|
Mouse |
|
|
autophagy
|
GO:0006914 |
88 |
0.257
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.256
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.255
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.247
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.247
|
|
|
|
microglial cell activation
|
GO:0001774 |
2 |
0.246
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.245
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.243
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.242
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.242
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.241
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.238
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.237
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.233
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.233
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.232
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.228
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.224
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.223
|
|
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
7 |
0.221
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.221
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.220
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.215
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.215
|
Mouse |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.212
|
|
|
|
macrophage activation
|
GO:0042116 |
12 |
0.212
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.211
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.210
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.210
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.210
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.209
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.207
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.204
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.203
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.202
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.200
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.200
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.197
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
2 |
0.197
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.196
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.196
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.195
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.192
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.192
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.189
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.187
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.186
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.185
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.185
|
|
|
|
interleukin 1 alpha secretion
|
GO:0050703 |
1 |
0.183
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.182
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.181
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.181
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.181
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.176
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.176
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.174
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.174
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.174
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.173
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.173
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.172
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
4 |
0.170
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.170
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.169
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.169
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.166
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.166
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.165
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.165
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
24 |
0.164
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.164
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.163
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.163
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.160
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.160
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.159
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.159
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.159
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.156
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.155
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.155
|
Mouse |
|
|
interferon beta production
|
GO:0032608 |
23 |
0.155
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.154
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.154
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.153
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.152
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.152
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.152
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.152
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.150
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.150
|
|
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.149
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.149
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.147
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.146
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.146
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.146
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.144
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.142
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.142
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.142
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.141
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.141
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.140
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.140
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.139
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.137
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.137
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.135
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.134
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.134
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.134
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.133
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.133
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.133
|
|
|
|
positive regulation of antigen processing and presentation
|
GO:0002579 |
1 |
0.132
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.132
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.132
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.132
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.131
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.131
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.131
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.131
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.129
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.129
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
15 |
0.128
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.128
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.127
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.127
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.126
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.126
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.126
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.126
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.126
|
|
|
|
macrophage differentiation
|
GO:0030225 |
11 |
0.125
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.124
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.124
|
|
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.123
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.123
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.122
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.121
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.121
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.120
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.119
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.118
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.116
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.116
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
14 |
0.115
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.115
|
Mouse |
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.114
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.114
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.113
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.113
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.113
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.113
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.111
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.111
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.110
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.110
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.110
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.109
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.109
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.108
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.108
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.108
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.108
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.107
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.107
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.107
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.105
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.105
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.105
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.104
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.104
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.103
|
|
|
|
pinocytosis
|
GO:0006907 |
8 |
0.103
|
|
|
|
type i interferon production
|
GO:0032606 |
27 |
0.103
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.102
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.102
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.101
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.100
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.100
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.100
|
|
|
|
detection of chemical stimulus
|
GO:0009593 |
55 |
0.098
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.098
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.097
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.097
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.096
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.095
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.095
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.093
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.093
|
|
|
|
lung development
|
GO:0030324 |
20 |
0.093
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.092
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.092
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.092
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.092
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.091
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.091
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.091
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.091
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.090
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.090
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.090
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.089
|
|
|
|
regulation of circadian sleep wake cycle non rem sleep
|
GO:0045188 |
1 |
0.089
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.089
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.089
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.089
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.089
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.088
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.087
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.087
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.086
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.086
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.086
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.086
|
|
|
|
interleukin 1 alpha production
|
GO:0032610 |
2 |
0.085
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.085
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.085
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.084
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.084
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.083
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.082
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.081
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.081
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.081
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.080
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.080
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.080
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.079
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.079
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.078
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.078
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.078
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.078
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.078
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.077
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.076
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.076
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.076
|
|
|
|
positive regulation of mhc class i biosynthetic process
|
GO:0045345 |
4 |
0.076
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.076
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.076
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.075
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.074
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.073
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.072
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.071
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.071
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.071
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.071
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.070
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.070
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.069
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.068
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.068
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.066
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.066
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.066
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.066
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.066
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.066
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.066
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.066
|
|
|
|
secondary metabolic process
|
GO:0019748 |
17 |
0.066
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.065
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.064
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.064
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.063
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.063
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.062
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.062
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.062
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.062
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.062
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.061
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.061
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.061
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.061
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.061
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.060
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.060
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.059
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.058
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.058
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.056
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.056
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.056
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.055
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.055
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.055
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.055
|
|
|
|
regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010803 |
12 |
0.055
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.055
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.054
|
|
|
|
positive regulation of circadian sleep wake cycle sleep
|
GO:0045938 |
1 |
0.054
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.053
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
11 |
0.053
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.053
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.053
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.053
|
|
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.052
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.052
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.052
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.052
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.051
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.050
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.049
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.049
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.049
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.049
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.049
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
0.048
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.048
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.048
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.048
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.047
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.047
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.047
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.046
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.046
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.046
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.045
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.045
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.045
|
|
|
|
negative regulation of type i interferon production
|
GO:0032480 |
5 |
0.045
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.044
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.044
|
|
|
|
respiratory tube development
|
GO:0030323 |
20 |
0.044
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
11 |
0.044
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.044
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.044
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.043
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.043
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.042
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
15 |
0.042
|
|
|
|
membrane depolarization
|
GO:0051899 |
26 |
0.041
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.041
|
|
|
|
detection of external biotic stimulus
|
GO:0098581 |
19 |
0.041
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.041
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.040
|
Mouse |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.040
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
18 |
0.040
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.040
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.039
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.039
|
|
