Homo sapiens

144 known processes

NME2

non-metastatic cells 2, protein (NM23B) expressed in

(Aliases: NDPK-B,NDKB,NDPKB,NM23-H2,MGC111212,NM23B,PUF,MGC2212)

NME2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of epithelial cell proliferation GO:0050679 65 0.989
positive regulation of cell proliferation GO:0008284 301 0.983
keratinocyte differentiation GO:0030216 36 0.982
regulation of cell differentiation GO:0045595 393 0.978
integrin mediated signaling pathway GO:0007229 32 0.976
epidermis development GO:0008544 59 0.962
positive regulation of epidermis development GO:0045684 11 0.903
epithelial cell proliferation GO:0050673 128 0.896
regulation of camp metabolic process GO:0030814 52 0.876
Rat
camp metabolic process GO:0046058 61 0.871
Rat
nucleoside phosphate biosynthetic process GO:1901293 109 0.844
regulation of cell development GO:0060284 161 0.831
Rat
positive regulation of epidermal cell differentiation GO:0045606 8 0.814
regulation of keratinocyte differentiation GO:0045616 11 0.801
positive regulation of cell differentiation GO:0045597 211 0.780
regulation of camp biosynthetic process GO:0030817 45 0.748
Rat
regulation of nucleotide metabolic process GO:0006140 269 0.726
Rat
negative regulation of apoptotic process GO:0043066 316 0.717
regulation of epithelial cell proliferation GO:0050678 113 0.703
epidermal cell differentiation GO:0009913 45 0.702
regulation of epidermal cell differentiation GO:0045604 15 0.689
organophosphate biosynthetic process GO:0090407 163 0.653
regulation of nucleotide biosynthetic process GO:0030808 50 0.622
Rat
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.606
Rat
epithelium development GO:0060429 227 0.583
lipid biosynthetic process GO:0008610 177 0.582
lipid metabolic process GO:0006629 381 0.566
nucleoside triphosphate biosynthetic process GO:0009142 20 0.532
nucleoside diphosphate metabolic process GO:0009132 16 0.530
regulation of cellular component movement GO:0051270 334 0.513
Worm
post embryonic development GO:0009791 2 0.505
Worm
regulation of purine nucleotide metabolic process GO:1900542 264 0.496
Rat
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.469
Rat
small molecule catabolic process GO:0044282 92 0.429
negative regulation of multicellular organismal process GO:0051241 317 0.428
Rat
camp biosynthetic process GO:0006171 47 0.426
Rat
protein oligomerization GO:0051259 173 0.419
Rat
ribonucleotide biosynthetic process GO:0009260 81 0.418
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.414
Rat
positive regulation of keratinocyte differentiation GO:0045618 6 0.392
positive regulation of nucleotide metabolic process GO:0045981 230 0.383
Rat
carboxylic acid catabolic process GO:0046395 71 0.380
positive regulation of developmental process GO:0051094 314 0.366
cellular amine metabolic process GO:0044106 41 0.361
protein homooligomerization GO:0051260 100 0.353
skin development GO:0043588 76 0.352
negative regulation of cell proliferation GO:0008285 228 0.350
purine nucleoside triphosphate metabolic process GO:0009144 412 0.340
Rat
cellular macromolecular complex assembly GO:0034622 324 0.302
fatty acid metabolic process GO:0006631 115 0.285
purine ribonucleotide biosynthetic process GO:0009152 79 0.266
Rat
monocarboxylic acid catabolic process GO:0072329 37 0.262
defense response GO:0006952 315 0.260
regulation of cellular ketone metabolic process GO:0010565 50 0.259
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.259
Rat
small gtpase mediated signal transduction GO:0007264 78 0.257
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.250
Rat
regulation of cell migration GO:0030334 289 0.249
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.244
innate immune response GO:0045087 178 0.224
negative regulation of cell death GO:0060548 345 0.215
regulation of locomotion GO:0040012 329 0.212
Worm
regulation of epidermis development GO:0045682 19 0.210
ribonucleotide catabolic process GO:0009261 405 0.206
regulation of cellular amino acid metabolic process GO:0006521 6 0.200
cellular amino acid metabolic process GO:0006520 116 0.199
amine metabolic process GO:0009308 44 0.198
protein tetramerization GO:0051262 47 0.192
response to organonitrogen compound GO:0010243 156 0.183
Rat
cellular ketone metabolic process GO:0042180 80 0.181
negative regulation of phosphate metabolic process GO:0045936 267 0.177
lipid modification GO:0030258 84 0.175
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.174
Rat
oxidation reduction process GO:0055114 396 0.161
cell projection organization GO:0030030 252 0.160
Rat
lipid oxidation GO:0034440 33 0.155
negative regulation of cellular protein metabolic process GO:0032269 353 0.142
positive regulation of protein phosphorylation GO:0001934 313 0.140
positive regulation of cellular amine metabolic process GO:0033240 7 0.139
ribonucleoside triphosphate metabolic process GO:0009199 412 0.139
Rat
cellular response to dna damage stimulus GO:0006974 379 0.139
cellular lipid catabolic process GO:0044242 65 0.137
inflammatory response GO:0006954 79 0.136
signal transduction by phosphorylation GO:0023014 297 0.134
Worm
negative regulation of protein metabolic process GO:0051248 391 0.128
positive regulation of camp metabolic process GO:0030816 41 0.123
Rat
vesicle mediated transport GO:0016192 371 0.123
Worm
regulation of protein kinase activity GO:0045859 289 0.117
cellular macromolecule catabolic process GO:0044265 380 0.117
fatty acid beta oxidation GO:0006635 22 0.113
nucleotide biosynthetic process GO:0009165 109 0.109
cyclic purine nucleotide metabolic process GO:0052652 60 0.106
Rat
purine nucleotide catabolic process GO:0006195 405 0.105
negative regulation of programmed cell death GO:0043069 321 0.105
fatty acid catabolic process GO:0009062 29 0.105
cellular homeostasis GO:0019725 196 0.104
Rat
negative regulation of cellular component organization GO:0051129 235 0.101
regulation of protein localization GO:0032880 296 0.100
guanosine containing compound metabolic process GO:1901068 244 0.099
Rat
rho protein signal transduction GO:0007266 26 0.097
response to oxidative stress GO:0006979 121 0.097
Rat
response to biotic stimulus GO:0009607 276 0.094
organic acid catabolic process GO:0016054 71 0.093
positive regulation of neurogenesis GO:0050769 49 0.092
Rat
pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 1 0.091
Rat
ras protein signal transduction GO:0007265 73 0.090
cellular response to oxidative stress GO:0034599 85 0.088
Rat
blood circulation GO:0008015 113 0.088
positive regulation of cell development GO:0010720 92 0.087
Rat
chemotaxis GO:0006935 157 0.087
positive regulation of neuron differentiation GO:0045666 40 0.085
Rat
ubiquitin dependent protein catabolic process GO:0006511 206 0.085
immune response GO:0006955 307 0.081
purine ribonucleoside metabolic process GO:0046128 437 0.081
Rat
negative regulation of phosphorylation GO:0042326 174 0.080
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.080
regulation of cell morphogenesis GO:0022604 153 0.080
regulation of response to wounding GO:1903034 101 0.079
erk1 and erk2 cascade GO:0070371 104 0.077
taxis GO:0042330 157 0.076
negative regulation of cell development GO:0010721 48 0.075
nucleoside triphosphate metabolic process GO:0009141 422 0.074
positive regulation of transport GO:0051050 336 0.073
cellular chemical homeostasis GO:0055082 180 0.072
Rat
negative regulation of protein modification process GO:0031400 200 0.071
regulation of cell projection organization GO:0031344 107 0.070
Rat
negative regulation of developmental process GO:0051093 247 0.069
Rat
regulation of cell cycle process GO:0010564 266 0.067
chemical homeostasis GO:0048878 306 0.067
Rat
modification dependent macromolecule catabolic process GO:0043632 212 0.066
cellular response to oxygen containing compound GO:1901701 276 0.066
Rat
negative regulation of phosphorus metabolic process GO:0010563 267 0.066
regulation of response to external stimulus GO:0032101 222 0.065
purine ribonucleoside catabolic process GO:0046130 398 0.064
organelle assembly GO:0070925 176 0.064
regulation of gtpase activity GO:0043087 180 0.064
negative regulation of protein phosphorylation GO:0001933 140 0.063
response to external biotic stimulus GO:0043207 261 0.060
pyrimidine nucleotide biosynthetic process GO:0006221 2 0.060
Rat
nucleoside phosphate catabolic process GO:1901292 412 0.060
regulation of cell cycle GO:0051726 393 0.060
circulatory system process GO:0003013 113 0.059
cellular lipid metabolic process GO:0044255 303 0.059
ribonucleoprotein complex subunit organization GO:0071826 81 0.059
cellular response to acid chemical GO:0071229 44 0.058
Rat
cellular response to lipid GO:0071396 127 0.056
Rat
gtp catabolic process GO:0006184 237 0.056
generation of neurons GO:0048699 152 0.056
Rat
negative regulation of cell migration GO:0030336 102 0.056
purine nucleoside catabolic process GO:0006152 398 0.055
purine nucleoside triphosphate catabolic process GO:0009146 392 0.055
negative regulation of cell differentiation GO:0045596 171 0.054
Rat
cell development GO:0048468 328 0.054
Rat
regulation of kinase activity GO:0043549 314 0.054
regulation of dna binding GO:0051101 37 0.053
cytokine production GO:0001816 247 0.053
defense response to other organism GO:0098542 129 0.053
anatomical structure homeostasis GO:0060249 100 0.052
cell morphogenesis GO:0000902 296 0.052
negative regulation of cell motility GO:2000146 104 0.052
reproductive process GO:0022414 106 0.051
Worm
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.051
regulation of purine nucleotide catabolic process GO:0033121 205 0.051
ameboidal type cell migration GO:0001667 135 0.051
purine ribonucleoside biosynthetic process GO:0046129 23 0.051
Rat
regulation of growth GO:0040008 165 0.050
response to other organism GO:0051707 261 0.050
regulation of defense response GO:0031347 154 0.049
organonitrogen compound biosynthetic process GO:1901566 200 0.049
Rat
epithelium migration GO:0090132 119 0.048
dephosphorylation GO:0016311 209 0.048
oogenesis GO:0048477 2 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
negative regulation of protein maturation GO:1903318 142 0.046
carbohydrate derivative biosynthetic process GO:1901137 207 0.046
Rat
immune effector process GO:0002252 159 0.045
regulation of nucleotide catabolic process GO:0030811 205 0.045
dna catabolic process GO:0006308 49 0.045
negative regulation of immune system process GO:0002683 136 0.045
Rat
regulation of anatomical structure morphogenesis GO:0022603 286 0.044
response to acid chemical GO:0001101 66 0.044
Rat
purine nucleotide biosynthetic process GO:0006164 84 0.044
Rat
regulation of protein transport GO:0051223 213 0.044
negative regulation of cellular amine metabolic process GO:0033239 3 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.043
positive regulation of cellular component movement GO:0051272 181 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.042
positive regulation of phosphorylation GO:0042327 394 0.042
Worm
regulation of protein catabolic process GO:0042176 155 0.042
chromatin modification GO:0016568 298 0.041
negative regulation of transport GO:0051051 176 0.041
regulation of epithelial cell differentiation GO:0030856 24 0.041
modification dependent protein catabolic process GO:0019941 209 0.041
cellular glucose homeostasis GO:0001678 11 0.041
Rat
regulation of binding GO:0051098 111 0.041
regulation of myeloid cell differentiation GO:0045637 81 0.041
Rat
pyrimidine containing compound metabolic process GO:0072527 19 0.040
Rat
ribonucleoprotein complex assembly GO:0022618 78 0.040
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
positive regulation of mapk cascade GO:0043410 190 0.040
Worm
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.040
Rat
negative regulation of leukocyte differentiation GO:1902106 24 0.040
Rat
tissue migration GO:0090130 119 0.040
mitotic cell cycle phase transition GO:0044772 162 0.039
negative regulation of cellular component movement GO:0051271 106 0.039
receptor mediated endocytosis GO:0006898 84 0.039
Worm
response to peptide GO:1901652 65 0.039
Rat
regulation of inflammatory response GO:0050727 46 0.039
nucleoside diphosphate phosphorylation GO:0006165 12 0.039
locomotory behavior GO:0007626 1 0.038
regulation of proteolysis GO:0030162 293 0.038
organophosphate catabolic process GO:0046434 430 0.037
negative regulation of protein processing GO:0010955 142 0.037
response to carbohydrate GO:0009743 21 0.036
Rat
cellular response to growth factor stimulus GO:0071363 197 0.036
gtp metabolic process GO:0046039 239 0.035
Rat
fatty acid oxidation GO:0019395 31 0.035
neuron development GO:0048666 113 0.035
Rat
response to hexose GO:0009746 20 0.035
Rat
endocytosis GO:0006897 159 0.035
Worm
regulation of secretion GO:0051046 194 0.034
peptidyl serine phosphorylation GO:0018105 101 0.034
positive regulation of immune system process GO:0002684 283 0.033
regulation of establishment of protein localization GO:0070201 242 0.033
regulation of innate immune response GO:0045088 97 0.033
pyrimidine ribonucleoside triphosphate metabolic process GO:0009208 2 0.033
Rat
positive regulation of cellular component organization GO:0051130 376 0.032
Rat
regulation of nervous system development GO:0051960 88 0.032
Rat
response to oxygen containing compound GO:1901700 369 0.032
Rat
protein catabolic process GO:0030163 325 0.032
cellular component morphogenesis GO:0032989 314 0.032
retina homeostasis GO:0001895 42 0.032
dna repair GO:0006281 198 0.032
regulation of epithelial cell migration GO:0010632 93 0.032
epithelial cell migration GO:0010631 119 0.032
defense response to bacterium GO:0042742 63 0.031
response to abiotic stimulus GO:0009628 336 0.030
positive regulation of kinase activity GO:0033674 204 0.030
nucleotide phosphorylation GO:0046939 15 0.030
cell cycle checkpoint GO:0000075 117 0.030
positive regulation of protein kinase activity GO:0045860 190 0.030
negative regulation of apoptotic signaling pathway GO:2001234 97 0.030
regulation of intracellular transport GO:0032386 195 0.029
multicellular organismal homeostasis GO:0048871 67 0.029
single organism membrane organization GO:0044802 268 0.029
negative regulation of transferase activity GO:0051348 124 0.029
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.029
regulation of secretion by cell GO:1903530 177 0.029
tissue morphogenesis GO:0048729 96 0.028
cytoplasmic transport GO:0016482 379 0.028
regulation of ras protein signal transduction GO:0046578 155 0.028
cellular response to carbohydrate stimulus GO:0071322 11 0.028
Rat
negative regulation of catalytic activity GO:0043086 335 0.028
regulation of myeloid leukocyte differentiation GO:0002761 39 0.028
Rat
regulation of erk1 and erk2 cascade GO:0070372 99 0.027
positive regulation of cell migration GO:0030335 172 0.027
peptidyl tyrosine modification GO:0018212 170 0.027
guanosine containing compound catabolic process GO:1901069 239 0.027
positive regulation of cell projection organization GO:0031346 64 0.027
Rat
response to bacterium GO:0009617 144 0.026
regulation of cytoplasmic transport GO:1903649 149 0.026
purine ribonucleotide catabolic process GO:0009154 404 0.026
negative regulation of epithelial cell migration GO:0010633 38 0.026
carboxylic acid biosynthetic process GO:0046394 97 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.026
regulation of mitotic cell cycle phase transition GO:1901990 118 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.026
regulation of gtp catabolic process GO:0033124 180 0.026
chromatin organization GO:0006325 351 0.026
intrinsic apoptotic signaling pathway GO:0097193 127 0.025
mapk cascade GO:0000165 288 0.025
Worm
negative regulation of kinase activity GO:0033673 106 0.025
regulation of nucleoside metabolic process GO:0009118 209 0.025
regulation of cell motility GO:2000145 299 0.025
Worm
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.025
embryonic morphogenesis GO:0048598 85 0.024
pyrimidine nucleoside metabolic process GO:0006213 13 0.024
Rat
alpha amino acid metabolic process GO:1901605 72 0.024
angiogenesis GO:0001525 147 0.024
regulation of intracellular protein transport GO:0033157 123 0.024
rna processing GO:0006396 255 0.024
regulation of ras gtpase activity GO:0032318 128 0.024
negative regulation of protein transport GO:0051224 75 0.024
regulation of protein maturation GO:1903317 150 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
establishment of protein localization to membrane GO:0090150 121 0.024
cell cycle phase transition GO:0044770 173 0.024
regulation of leukocyte differentiation GO:1902105 61 0.024
Rat
oocyte development GO:0048599 1 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
negative regulation of proteolysis GO:0045861 132 0.023
regulation of lipid biosynthetic process GO:0046890 47 0.023
cell matrix adhesion GO:0007160 85 0.023
regulation of ion transport GO:0043269 189 0.022
regulation of protein binding GO:0043393 66 0.022
histone modification GO:0016570 251 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
reactive oxygen species biosynthetic process GO:1903409 4 0.022
actin cytoskeleton organization GO:0030036 207 0.022
positive regulation of nervous system development GO:0051962 54 0.021
Rat
regulation of neuron projection development GO:0010975 57 0.021
Rat
cell division GO:0051301 168 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
blood vessel morphogenesis GO:0048514 162 0.021
negative regulation of protein binding GO:0032091 35 0.021
cell substrate adhesion GO:0031589 132 0.021
protein ubiquitination GO:0016567 314 0.021
neurogenesis GO:0022008 169 0.021
Rat
leukocyte differentiation GO:0002521 98 0.021
Rat
cell morphogenesis involved in differentiation GO:0000904 144 0.021
negative regulation of mitotic cell cycle GO:0045930 102 0.021
single organism cell adhesion GO:0098602 179 0.021
regulation of protein processing GO:0070613 150 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.020
positive regulation of protein localization to nucleus GO:1900182 48 0.020
positive regulation of locomotion GO:0040017 186 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
enzyme linked receptor protein signaling pathway GO:0007167 303 0.020
female gamete generation GO:0007292 2 0.020
regulation of cellular response to stress GO:0080135 244 0.020
myeloid cell differentiation GO:0030099 117 0.020
Rat
protein dephosphorylation GO:0006470 81 0.020
negative regulation of cell cycle GO:0045786 193 0.020
regulation of cell adhesion GO:0030155 166 0.020
positive regulation of cell motility GO:2000147 177 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.019
nuclear transport GO:0051169 179 0.019
mitotic cell cycle GO:0000278 326 0.019
cellular response to glucose stimulus GO:0071333 10 0.019
Rat
positive regulation of cell cycle GO:0045787 140 0.019
response to monosaccharide GO:0034284 20 0.019
Rat
response to nitrogen compound GO:1901698 184 0.019
Rat
myeloid leukocyte migration GO:0097529 62 0.019
response to lipid GO:0033993 206 0.018
Rat
regulation of rho gtpase activity GO:0032319 66 0.018
cyclic nucleotide metabolic process GO:0009187 82 0.018
Rat
hematopoietic or lymphoid organ development GO:0048534 186 0.018
Rat
proteasomal protein catabolic process GO:0010498 176 0.018
activation of protein kinase activity GO:0032147 90 0.018
negative regulation of response to external stimulus GO:0032102 83 0.018
response to wounding GO:0009611 168 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
epithelial cell differentiation GO:0030855 141 0.018
regulation of proteasomal protein catabolic process GO:0061136 87 0.018
vascular process in circulatory system GO:0003018 29 0.018
protein maturation GO:0051604 233 0.018
positive regulation of innate immune response GO:0045089 79 0.018
negative regulation of catabolic process GO:0009895 104 0.018
peptidyl tyrosine phosphorylation GO:0018108 170 0.017
positive regulation of immune response GO:0050778 159 0.017
positive regulation of catabolic process GO:0009896 310 0.017
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.017
Rat
system process GO:0003008 349 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
regulation of angiogenesis GO:0045765 92 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
glycoprotein metabolic process GO:0009100 110 0.017
positive regulation of ras gtpase activity GO:0032320 117 0.017
hemopoiesis GO:0030097 180 0.017
Rat
regulation of autophagy GO:0010506 52 0.017
cell activation GO:0001775 213 0.017
regulation of neuron death GO:1901214 56 0.017
regulation of vasculature development GO:1901342 97 0.017
glutamate metabolic process GO:0006536 10 0.016
calcium ion transport GO:0006816 147 0.016
regulation of blood vessel size GO:0050880 18 0.016
regulation of immune response GO:0050776 201 0.016
negative regulation of response to wounding GO:1903035 47 0.016
tissue homeostasis GO:0001894 63 0.016
regulation of rho protein signal transduction GO:0035023 79 0.016
cell cell signaling GO:0007267 155 0.016
apoptotic signaling pathway GO:0097190 268 0.016
regulation of neuron differentiation GO:0045664 70 0.016
Rat
regulation of transferase activity GO:0051338 355 0.016
response to peptide hormone GO:0043434 61 0.016
Rat
chromosome segregation GO:0007059 114 0.015
positive regulation of epithelial cell differentiation GO:0030858 14 0.015
regulation of cellular protein catabolic process GO:1903362 96 0.015
oocyte differentiation GO:0009994 2 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
response to fungus GO:0009620 4 0.015
positive regulation of defense response GO:0031349 87 0.015
cell part morphogenesis GO:0032990 137 0.015
positive regulation of binding GO:0051099 45 0.015
ion homeostasis GO:0050801 230 0.015
regulation of dna metabolic process GO:0051052 153 0.015
positive regulation of secretion GO:0051047 116 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.015
cellular protein catabolic process GO:0044257 261 0.014
secretion GO:0046903 254 0.014
regulation of mapk cascade GO:0043408 262 0.014
Worm
protein targeting GO:0006605 187 0.014
single organism cellular localization GO:1902580 332 0.014
response to reactive oxygen species GO:0000302 61 0.014
regulation of neurogenesis GO:0050767 82 0.014
Rat
protein homotetramerization GO:0051289 28 0.014
cellular cation homeostasis GO:0030003 163 0.014
regulation of immune effector process GO:0002697 91 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
sex differentiation GO:0007548 45 0.014
Worm
cell type specific apoptotic process GO:0097285 125 0.014
glycerophospholipid metabolic process GO:0006650 84 0.014
regulation of protein dephosphorylation GO:0035304 18 0.014
negative regulation of protein kinase activity GO:0006469 98 0.014
response to growth factor GO:0070848 205 0.014
purine ribonucleoside triphosphate biosynthetic process GO:0009206 11 0.013
Rat
cell projection assembly GO:0030031 126 0.013
growth GO:0040007 202 0.013
sequestering of metal ion GO:0051238 24 0.013
response to hormone GO:0009725 175 0.013
Rat
protein secretion GO:0009306 98 0.013
digestion GO:0007586 22 0.013
dna conformation change GO:0071103 113 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
cellular response to hexose stimulus GO:0071331 10 0.013
Rat
endothelial cell proliferation GO:0001935 65 0.013
nucleoside catabolic process GO:0009164 408 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
response to glucose GO:0009749 19 0.013
Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
adult locomotory behavior GO:0008344 1 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
cell cycle arrest GO:0007050 71 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
regulation of cytokine production GO:0001817 232 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
positive regulation of response to external stimulus GO:0032103 88 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
negative regulation of immune response GO:0050777 40 0.012
positive regulation of dna binding GO:0043388 17 0.012
peripheral nervous system development GO:0007422 2 0.012
negative regulation of intracellular transport GO:0032387 60 0.012
amide transport GO:0042886 76 0.012
pyrimidine containing compound biosynthetic process GO:0072528 4 0.012
Rat
positive regulation of cell cycle process GO:0090068 106 0.012
ribose phosphate biosynthetic process GO:0046390 82 0.012
Rat
negative regulation of cell cycle arrest GO:0071157 12 0.012
myeloid leukocyte differentiation GO:0002573 60 0.012
Rat
hindbrain development GO:0030902 3 0.012
positive regulation of proteolysis GO:0045862 142 0.012
positive regulation of protein transport GO:0051222 135 0.012
regulation of signal transduction by p53 class mediator GO:1901796 26 0.012
negative regulation of neuron apoptotic process GO:0043524 23 0.012
divalent inorganic cation transport GO:0072511 158 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.012
intracellular receptor signaling pathway GO:0030522 104 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
generation of precursor metabolites and energy GO:0006091 68 0.012
carbohydrate metabolic process GO:0005975 207 0.012
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.011
Worm
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
epithelial to mesenchymal transition GO:0001837 48 0.011
blastoderm segmentation GO:0007350 2 0.011
microtubule based process GO:0007017 210 0.011
divalent metal ion transport GO:0070838 152 0.011
intracellular protein transport GO:0006886 270 0.011
pyrimidine ribonucleoside biosynthetic process GO:0046132 2 0.011
Rat
cation transport GO:0006812 331 0.011
metal ion homeostasis GO:0055065 169 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
regulation of chromosome organization GO:0033044 103 0.011
protein targeting to nucleus GO:0044744 104 0.011
fibroblast proliferation GO:0048144 33 0.011
response to light stimulus GO:0009416 87 0.011
response to growth hormone GO:0060416 11 0.011
Rat
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
digestive tract development GO:0048565 75 0.011
regulation of peptide transport GO:0090087 62 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
regulation of metal ion transport GO:0010959 120 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
immune system development GO:0002520 195 0.011
Rat
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
stem cell differentiation GO:0048863 93 0.011
sequestering of calcium ion GO:0051208 17 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.011
reproductive structure development GO:0048608 55 0.011
Worm
nucleotide catabolic process GO:0009166 408 0.011
muscle structure development GO:0061061 98 0.010

NME2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.092
cancer DOID:162 167 0.049
organ system cancer DOID:0050686 164 0.039
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
immune system disease DOID:2914 155 0.017
hematopoietic system disease DOID:74 100 0.017
disease of metabolism DOID:0014667 295 0.015
neuromuscular disease DOID:440 38 0.014
neuropathy DOID:870 52 0.014
neurodegenerative disease DOID:1289 102 0.011