Homo sapiens

73 known processes

NONO

non-POU domain containing, octamer-binding

(Aliases: NRB54,P54,NMT55,P54NRB)

NONO biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902177 4 0.878
Human
negative regulation of oxidative stress induced cell death GO:1903202 17 0.787
multicellular organismal aging GO:0010259 3 0.607
determination of adult lifespan GO:0008340 2 0.605
chromatin modification GO:0016568 298 0.602
positive regulation of oxidative stress induced cell death GO:1903209 5 0.525
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.477
Human
post embryonic development GO:0009791 2 0.454
Worm
sensory perception of light stimulus GO:0050953 35 0.451
Fly
rna splicing GO:0008380 131 0.444
Human
mrna processing GO:0006397 133 0.424
Human
negative regulation of apoptotic process GO:0043066 316 0.406
mrna metabolic process GO:0016071 175 0.387
Human
negative regulation of oxidative stress induced neuron death GO:1903204 7 0.364
mrna splicing via spliceosome GO:0000398 89 0.333
Human
oogenesis GO:0048477 2 0.325
negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903377 5 0.320
negative regulation of neuron apoptotic process GO:0043524 23 0.318
positive regulation of developmental process GO:0051094 314 0.302
regulation of axon regeneration GO:0048679 1 0.297
nitrogen compound transport GO:0071705 191 0.259
growth GO:0040007 202 0.225
Worm
negative regulation of cell death GO:0060548 345 0.215
chromatin organization GO:0006325 351 0.214
system process GO:0003008 349 0.208
Fly
regulation of neuron projection regeneration GO:0070570 1 0.202
nucleic acid transport GO:0050657 39 0.197
cytoplasmic transport GO:0016482 379 0.184
rna catabolic process GO:0006401 71 0.182
negative regulation of cellular catabolic process GO:0031330 83 0.180
cellular amino acid metabolic process GO:0006520 116 0.177
negative regulation of programmed cell death GO:0043069 321 0.171
posttranscriptional regulation of gene expression GO:0010608 213 0.171
nervous system development GO:0007399 293 0.170
regulation of oxidative stress induced cell death GO:1903201 24 0.169
cardiovascular system development GO:0072358 262 0.167
cellular response to dna damage stimulus GO:0006974 379 0.153
cell death in response to oxidative stress GO:0036473 29 0.144
female gamete generation GO:0007292 2 0.144
translation GO:0006412 132 0.138
intrinsic apoptotic signaling pathway GO:0097193 127 0.137
locomotory behavior GO:0007626 1 0.133
chemical homeostasis GO:0048878 306 0.127
neuron death in response to oxidative stress GO:0036475 9 0.122
regulation of gene expression epigenetic GO:0040029 73 0.119
cellular response to oxidative stress GO:0034599 85 0.115
cell projection organization GO:0030030 252 0.114
negative regulation of cellular component organization GO:0051129 235 0.112
metal ion transport GO:0030001 272 0.112
positive regulation of apoptotic signaling pathway GO:2001235 70 0.112
Human
rna stabilization GO:0043489 18 0.111
adult locomotory behavior GO:0008344 1 0.108
sensory perception GO:0007600 103 0.106
Fly
regulation of cellular response to stress GO:0080135 244 0.102
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.096
Human
viral process GO:0016032 146 0.095
multi organism cellular process GO:0044764 156 0.095
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 7 0.090
oxidation reduction process GO:0055114 396 0.086
mitotic nuclear division GO:0007067 119 0.085
negative regulation of protein metabolic process GO:0051248 391 0.084
immune effector process GO:0002252 159 0.084
cellular macromolecular complex assembly GO:0034622 324 0.084
interspecies interaction between organisms GO:0044419 156 0.083
cellular homeostasis GO:0019725 196 0.083
defense response GO:0006952 315 0.082
chromatin assembly or disassembly GO:0006333 78 0.082
regulation of multi organism process GO:0043900 157 0.082
mrna catabolic process GO:0006402 56 0.080
rna transport GO:0050658 39 0.079
negative regulation of neuron death GO:1901215 32 0.074
neuron development GO:0048666 113 0.074
negative regulation of chromatin silencing GO:0031936 4 0.074
regulation of mrna metabolic process GO:1903311 53 0.073
response to oxidative stress GO:0006979 121 0.073
cellular response to cytokine stimulus GO:0071345 181 0.072
negative regulation of phosphate metabolic process GO:0045936 267 0.072
regulation of cell development GO:0060284 161 0.071
circulatory system development GO:0072359 262 0.070
nucleoside catabolic process GO:0009164 408 0.068
neuron projection development GO:0031175 106 0.066
innate immune response GO:0045087 178 0.066
cellular divalent inorganic cation homeostasis GO:0072503 128 0.066
intracellular protein transport GO:0006886 270 0.064
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.064
regulation of response to oxidative stress GO:1902882 26 0.064
neuron differentiation GO:0030182 138 0.063
atp dependent chromatin remodeling GO:0043044 25 0.063
neurogenesis GO:0022008 169 0.063
demethylation GO:0070988 37 0.063
apoptotic signaling pathway GO:0097190 268 0.062
covalent chromatin modification GO:0016569 254 0.060
rna splicing via transesterification reactions GO:0000375 90 0.060
Human
dna demethylation GO:0080111 12 0.060
regulation of nervous system development GO:0051960 88 0.058
membrane organization GO:0061024 292 0.058
cofactor metabolic process GO:0051186 87 0.058
organonitrogen compound biosynthetic process GO:1901566 200 0.057
negative regulation of cell cycle GO:0045786 193 0.056
regulation of secretion GO:0051046 194 0.056
negative regulation of hydrolase activity GO:0051346 182 0.054
chemotaxis GO:0006935 157 0.053
regulation of cell cycle GO:0051726 393 0.053
organic acid biosynthetic process GO:0016053 97 0.051
cell development GO:0048468 328 0.050
cellular macromolecule catabolic process GO:0044265 380 0.049
positive regulation of apoptotic process GO:0043065 246 0.049
Human
reproductive structure development GO:0048608 55 0.049
response to abiotic stimulus GO:0009628 336 0.047
histone modification GO:0016570 251 0.047
mrna stabilization GO:0048255 18 0.047
cellular cation homeostasis GO:0030003 163 0.046
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.046
Human
negative regulation of catalytic activity GO:0043086 335 0.045
ornithine metabolic process GO:0006591 3 0.045
regulation of cell projection organization GO:0031344 107 0.045
positive regulation of cellular component organization GO:0051130 376 0.045
protein dna complex subunit organization GO:0071824 80 0.044
response to cytokine GO:0034097 232 0.043
protein deacylation GO:0035601 39 0.043
nucleoside triphosphate catabolic process GO:0009143 394 0.043
single organism membrane organization GO:0044802 268 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.043
regulation of translational elongation GO:0006448 2 0.041
establishment of protein localization to membrane GO:0090150 121 0.041
cellular response to oxygen containing compound GO:1901701 276 0.041
histone lysine methylation GO:0034968 50 0.041
mitotic cell cycle GO:0000278 326 0.041
regulation of intracellular transport GO:0032386 195 0.041
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 10 0.041
proline metabolic process GO:0006560 3 0.040
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 7 0.040
ras protein signal transduction GO:0007265 73 0.040
positive regulation of growth GO:0045927 58 0.039
response to oxygen containing compound GO:1901700 369 0.039
cellular chemical homeostasis GO:0055082 180 0.039
negative regulation of organelle organization GO:0010639 126 0.039
positive regulation of programmed cell death GO:0043068 249 0.039
Human
regulation of neurogenesis GO:0050767 82 0.039
negative regulation of axonogenesis GO:0050771 4 0.039
atrial septum primum morphogenesis GO:0003289 1 0.039
behavior GO:0007610 112 0.039
Fly
neurological system process GO:0050877 163 0.038
Fly
generation of neurons GO:0048699 152 0.038
response to wounding GO:0009611 168 0.038
negative regulation of cellular response to oxidative stress GO:1900408 18 0.037
carbohydrate metabolic process GO:0005975 207 0.037
response to biotic stimulus GO:0009607 276 0.036
regulation of mrna processing GO:0050684 48 0.036
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
regulation of translation GO:0006417 89 0.036
rna interference GO:0016246 4 0.036
cation transport GO:0006812 331 0.035
positive regulation of immune system process GO:0002684 283 0.035
oocyte development GO:0048599 1 0.034
sensory perception of pain GO:0019233 4 0.034
septum secundum development GO:0003285 2 0.034
cation homeostasis GO:0055080 189 0.033
rna polyadenylation GO:0043631 14 0.033
regulation of cellular response to oxidative stress GO:1900407 26 0.032
cell morphogenesis GO:0000902 296 0.032
negative regulation of response to external stimulus GO:0032102 83 0.032
protein deacetylation GO:0006476 38 0.032
embryo development GO:0009790 123 0.032
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.032
hemopoiesis GO:0030097 180 0.032
immune system development GO:0002520 195 0.032
small gtpase mediated signal transduction GO:0007264 78 0.032
negative regulation of cell differentiation GO:0045596 171 0.032
chromatin remodeling GO:0006338 55 0.031
negative regulation of catabolic process GO:0009895 104 0.031
macromolecule deacylation GO:0098732 41 0.031
ribonucleoprotein complex biogenesis GO:0022613 116 0.031
regulation of cell differentiation GO:0045595 393 0.031
single organism reproductive process GO:0044702 98 0.030
oocyte differentiation GO:0009994 2 0.030
cellular response to nitrogen compound GO:1901699 144 0.030
negative regulation of intracellular signal transduction GO:1902532 183 0.029
dna repair GO:0006281 198 0.029
dna dealkylation GO:0035510 13 0.029
mitotic cell cycle process GO:1903047 286 0.029
negative regulation of developmental process GO:0051093 247 0.029
Worm
cell part morphogenesis GO:0032990 137 0.029
regulation of cell cycle phase transition GO:1901987 126 0.029
positive regulation of isotype switching to iga isotypes GO:0048298 2 0.029
reproductive system development GO:0061458 56 0.029
cellular component morphogenesis GO:0032989 314 0.028
cellular ketone metabolic process GO:0042180 80 0.028
response to nitrogen compound GO:1901698 184 0.028
nuclear transcribed mrna catabolic process GO:0000956 48 0.028
rna processing GO:0006396 255 0.028
Human
development of primary sexual characteristics GO:0045137 35 0.028
negative regulation of multicellular organismal process GO:0051241 317 0.028
Worm
regulation of neuron death GO:1901214 56 0.027
organ morphogenesis GO:0009887 147 0.027
circadian rhythm GO:0007623 21 0.027
Mouse Rat
negative regulation of transport GO:0051051 176 0.026
posttranscriptional gene silencing by rna GO:0035194 25 0.026
regulation of cellular amino acid metabolic process GO:0006521 6 0.026
axon regeneration GO:0031103 1 0.026
cellular modified amino acid metabolic process GO:0006575 64 0.026
cell cycle phase transition GO:0044770 173 0.026
vesicle mediated transport GO:0016192 371 0.026
regulation of response to wounding GO:1903034 101 0.026
regulation of vesicle mediated transport GO:0060627 130 0.026
regulation of rna stability GO:0043487 23 0.026
sex differentiation GO:0007548 45 0.025
regulation of growth GO:0040008 165 0.025
double strand break repair GO:0006302 101 0.025
endocytosis GO:0006897 159 0.025
positive regulation of immune response GO:0050778 159 0.025
viral life cycle GO:0019058 132 0.024
trna 3 end processing GO:0042780 3 0.024
cellular modified amino acid biosynthetic process GO:0042398 15 0.024
protein stabilization GO:0050821 64 0.024
meiotic chromosome segregation GO:0045132 4 0.024
visual perception GO:0007601 27 0.024
Fly
regulation of proteolysis GO:0030162 293 0.024
reproduction GO:0000003 63 0.024
Worm Fly
positive regulation of transport GO:0051050 336 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.024
neuron projection regeneration GO:0031102 1 0.023
sexual reproduction GO:0019953 37 0.023
Fly
secretion GO:0046903 254 0.023
neuron projection morphogenesis GO:0048812 50 0.023
regulation of mrna stability GO:0043488 23 0.023
gene silencing GO:0016458 49 0.023
regulation of viral process GO:0050792 103 0.023
negative regulation of response to wounding GO:1903035 47 0.023
negative regulation of apoptotic signaling pathway GO:2001234 97 0.022
positive regulation of cell differentiation GO:0045597 211 0.022
muscle organ development GO:0007517 56 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
reproductive process GO:0022414 106 0.022
Fly
regulation of immunoglobulin production GO:0002637 4 0.022
cellular response to organonitrogen compound GO:0071417 124 0.022
negative regulation of cell cycle process GO:0010948 121 0.022
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
ion homeostasis GO:0050801 230 0.022
taxis GO:0042330 157 0.022
regulation of neuron apoptotic process GO:0043523 35 0.021
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
aging GO:0007568 66 0.021
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.021
activation of immune response GO:0002253 114 0.021
pigment biosynthetic process GO:0046148 10 0.021
nuclear export GO:0051168 69 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
regulation of response to external stimulus GO:0032101 222 0.021
positive regulation of dna metabolic process GO:0051054 73 0.021
cellular metal ion homeostasis GO:0006875 146 0.020
dna templated transcription termination GO:0006353 3 0.020
cell activation GO:0001775 213 0.020
organophosphate catabolic process GO:0046434 430 0.020
regulation of cell activation GO:0050865 125 0.020
immune response GO:0006955 307 0.020
protein localization to organelle GO:0033365 280 0.020
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.020
response to axon injury GO:0048678 1 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
mrna 3 end processing GO:0031124 24 0.019
negative regulation of intracellular protein transport GO:0090317 42 0.019
establishment of blood brain barrier GO:0060856 1 0.019
rna localization GO:0006403 41 0.019
response to other organism GO:0051707 261 0.019
ventricular septum morphogenesis GO:0060412 3 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
neuromuscular junction development GO:0007528 3 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
rna export from nucleus GO:0006405 33 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
regulation of cell migration GO:0030334 289 0.018
organelle fission GO:0048285 149 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
small molecule biosynthetic process GO:0044283 157 0.018
regulation of binding GO:0051098 111 0.018
organelle assembly GO:0070925 176 0.018
negative regulation of gene silencing by rna GO:0060967 3 0.018
negative regulation of gene expression epigenetic GO:0045814 19 0.018
regulation of neuron projection development GO:0010975 57 0.017
regulation of lymphocyte mediated immunity GO:0002706 33 0.017
tricarboxylic acid metabolic process GO:0072350 4 0.017
histone deacetylation GO:0016575 32 0.017
purine containing compound biosynthetic process GO:0072522 88 0.017
developmental process involved in reproduction GO:0003006 66 0.017
positive regulation of exocytosis GO:0045921 35 0.017
cellular ion homeostasis GO:0006873 168 0.017
rhythmic process GO:0048511 31 0.017
Mouse Rat
negative regulation of translation GO:0017148 37 0.017
dephosphorylation GO:0016311 209 0.017
multi organism reproductive process GO:0044703 54 0.017
Fly
regulation of meiotic cell cycle GO:0051445 4 0.017
metal ion homeostasis GO:0055065 169 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
positive regulation of response to oxidative stress GO:1902884 7 0.017
Human
response to temperature stimulus GO:0009266 22 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
negative regulation of multi organism process GO:0043901 92 0.016
cell projection morphogenesis GO:0048858 129 0.016
positive regulation of developmental growth GO:0048639 16 0.016
nucleosome positioning GO:0016584 3 0.016
regulation of dna metabolic process GO:0051052 153 0.016
wound healing GO:0042060 115 0.016
determination of bilateral symmetry GO:0009855 15 0.016
positive regulation of translation GO:0045727 35 0.016
regulation of immune effector process GO:0002697 91 0.016
cellular hyperosmotic response GO:0071474 4 0.015
response to drug GO:0042493 81 0.015
cell growth GO:0016049 160 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
monovalent inorganic cation transport GO:0015672 128 0.015
positive regulation of endopeptidase activity GO:0010950 84 0.015
nuclear transport GO:0051169 179 0.015
protein acylation GO:0043543 138 0.015
neuron apoptotic process GO:0051402 39 0.015
positive regulation of multi organism process GO:0043902 56 0.015
negative regulation of mitotic cell cycle GO:0045930 102 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
nucleosome organization GO:0034728 66 0.014
histone h3 deacetylation GO:0070932 9 0.014
chromatin silencing GO:0006342 12 0.014
positive regulation of cell activation GO:0050867 81 0.014
purine containing compound catabolic process GO:0072523 411 0.014
ossification GO:0001503 121 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
amine metabolic process GO:0009308 44 0.014
regulation of gene silencing GO:0060968 24 0.014
histone exchange GO:0043486 3 0.014
circulatory system process GO:0003013 113 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
negative regulation of cytoskeleton organization GO:0051494 45 0.014
ribose phosphate biosynthetic process GO:0046390 82 0.013
mating GO:0007618 1 0.013
Fly
blood circulation GO:0008015 113 0.013
response to transforming growth factor beta GO:0071559 94 0.013
regulation of cellular component movement GO:0051270 334 0.013
tripartite regional subdivision GO:0007351 2 0.013
single organism carbohydrate catabolic process GO:0044724 33 0.013
maintenance of gastrointestinal epithelium GO:0030277 8 0.013
compound eye development GO:0048749 1 0.013
negative regulation of phosphatase activity GO:0010923 61 0.013
negative regulation of response to oxidative stress GO:1902883 18 0.013
cell type specific apoptotic process GO:0097285 125 0.013
developmental growth GO:0048589 48 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
transmembrane transport GO:0055085 399 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
negative regulation of cell growth GO:0030308 83 0.013
lymphocyte activation GO:0046649 133 0.013
trabecula morphogenesis GO:0061383 2 0.013
positive regulation of cell death GO:0010942 263 0.013
Human
carboxylic acid biosynthetic process GO:0046394 97 0.013
positive regulation of lymphocyte activation GO:0051251 73 0.013
regulation of immune response GO:0050776 201 0.013
spermatid differentiation GO:0048515 4 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
termination of rna polymerase i transcription GO:0006363 1 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.012
negative regulation of binding GO:0051100 57 0.012
regulation of meiosis GO:0040020 3 0.012
negative regulation of protein transport GO:0051224 75 0.012
positive regulation of secretion GO:0051047 116 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
isotype switching GO:0045190 3 0.012
calcium ion homeostasis GO:0055074 122 0.012
connective tissue development GO:0061448 39 0.012
negative regulation of neuron projection development GO:0010977 15 0.012
spermatid development GO:0007286 4 0.012
protein methylation GO:0006479 74 0.012
regulation of protein transport GO:0051223 213 0.012
vasculature development GO:0001944 181 0.012
dna packaging GO:0006323 77 0.012
cellular response to organic cyclic compound GO:0071407 127 0.012
sensory organ development GO:0007423 52 0.012
negative regulation of cell cycle phase transition GO:1901988 89 0.012
response to heat GO:0009408 21 0.012
regulation of defense response GO:0031347 154 0.012
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.012
leukocyte activation GO:0045321 164 0.012
positive regulation of nervous system development GO:0051962 54 0.012
epithelium development GO:0060429 227 0.012
lung saccule development GO:0060430 2 0.012
g2 dna damage checkpoint GO:0031572 26 0.012
segmentation GO:0035282 4 0.011
tube morphogenesis GO:0035239 95 0.011
dna recombination GO:0006310 77 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
regeneration GO:0031099 4 0.011
detection of stimulus GO:0051606 85 0.011
negative regulation of nucleotide catabolic process GO:0030812 16 0.011
chromatin remodeling at centromere GO:0031055 2 0.011
anterior posterior axis specification GO:0009948 2 0.011
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.011
negative regulation of nucleotide metabolic process GO:0045980 29 0.011
cation transmembrane transport GO:0098655 238 0.011
protein maturation GO:0051604 233 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
methylation GO:0032259 106 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
tissue homeostasis GO:0001894 63 0.011
response to xenobiotic stimulus GO:0009410 30 0.011
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.010
endomembrane system organization GO:0010256 196 0.010
regulation of ion transport GO:0043269 189 0.010
ncrna metabolic process GO:0034660 108 0.010
negative regulation of neurogenesis GO:0050768 26 0.010
central nervous system development GO:0007417 123 0.010
divalent inorganic cation homeostasis GO:0072507 136 0.010
determination of heart left right asymmetry GO:0061371 8 0.010

NONO disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.168
neurodegenerative disease DOID:1289 102 0.168
nervous system disease DOID:863 431 0.168
disease of cellular proliferation DOID:14566 174 0.060
sensory system disease DOID:0050155 203 0.034
eye and adnexa disease DOID:1492 150 0.034
cancer DOID:162 167 0.026
organ system cancer DOID:0050686 164 0.017
neuromuscular disease DOID:440 38 0.014
charcot marie tooth disease DOID:10595 33 0.014
neuropathy DOID:870 52 0.014