Homo sapiens

114 known processes

NR1H4

nuclear receptor subfamily 1, group H, member 4

(Aliases: BAR,HRR-1,HRR1,RIP14,MGC163445,FXR)

NR1H4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
estrogen catabolic process GO:0006711 1 0.347
cellular response to genistein GO:0071412 1 0.273
cellular amino acid metabolic process GO:0006520 116 0.179
Mouse
amine metabolic process GO:0009308 44 0.151
Mouse
cellular ketone metabolic process GO:0042180 80 0.145
response to organic cyclic compound GO:0014070 204 0.136
Human Mouse Rat
response to oxygen containing compound GO:1901700 369 0.121
Human Mouse Rat
monocarboxylic acid metabolic process GO:0032787 185 0.116
lipid metabolic process GO:0006629 381 0.112
steroid metabolic process GO:0008202 94 0.108
cellular lipid metabolic process GO:0044255 303 0.105
anion transport GO:0006820 161 0.104
cellular response to hydroxyisoflavone GO:0071413 1 0.095
regulation of hormone levels GO:0010817 125 0.092
cellular response to oxygen containing compound GO:1901701 276 0.090
Human Mouse
system process GO:0003008 349 0.090
Human
oxidation reduction process GO:0055114 396 0.089
Human
lipid biosynthetic process GO:0008610 177 0.089
cellular amine metabolic process GO:0044106 41 0.088
Mouse
response to lipid GO:0033993 206 0.086
Human Mouse Rat
chemical homeostasis GO:0048878 306 0.086
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.085
carbohydrate metabolic process GO:0005975 207 0.077
Human Rat
regulation of cellular amine metabolic process GO:0033238 11 0.077
Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.076
Mouse
response to nitrogen compound GO:1901698 184 0.074
Human Mouse
organic anion transport GO:0015711 103 0.073
small molecule biosynthetic process GO:0044283 157 0.069
organic hydroxy compound metabolic process GO:1901615 147 0.067
single organism carbohydrate metabolic process GO:0044723 193 0.066
Human
post embryonic development GO:0009791 2 0.065
secretion GO:0046903 254 0.063
response to organonitrogen compound GO:0010243 156 0.062
Human Mouse
alkaloid metabolic process GO:0009820 4 0.061
response to xenobiotic stimulus GO:0009410 30 0.058
Human
cellular response to endogenous stimulus GO:0071495 336 0.058
Human Mouse Rat
immune response GO:0006955 307 0.057
Human
transmembrane transport GO:0055085 399 0.056
positive regulation of cellular amine metabolic process GO:0033240 7 0.056
Mouse
response to hormone GO:0009725 175 0.056
Human Rat
regeneration GO:0031099 4 0.055
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.052
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.052
defense response GO:0006952 315 0.051
Human
response to other organism GO:0051707 261 0.049
Rat
organic acid biosynthetic process GO:0016053 97 0.049
innate immune response GO:0045087 178 0.047
Human
nitrogen cycle metabolic process GO:0071941 3 0.044
Mouse
hormone metabolic process GO:0042445 61 0.043
fatty acid metabolic process GO:0006631 115 0.042
negative regulation of cellular protein metabolic process GO:0032269 353 0.041
cellular response to xenobiotic stimulus GO:0071466 29 0.040
Human
carboxylic acid biosynthetic process GO:0046394 97 0.039
ion transmembrane transport GO:0034220 338 0.039
sensory perception of smell GO:0007608 2 0.039
sulfur compound metabolic process GO:0006790 101 0.039
determination of adult lifespan GO:0008340 2 0.039
isoprenoid metabolic process GO:0006720 39 0.038
organonitrogen compound biosynthetic process GO:1901566 200 0.038
regulation of locomotion GO:0040012 329 0.038
cytoplasmic transport GO:0016482 379 0.038
regulation of response to external stimulus GO:0032101 222 0.038
multicellular organismal aging GO:0010259 3 0.036
positive regulation of phosphorylation GO:0042327 394 0.036
female gamete generation GO:0007292 2 0.036
cellular chemical homeostasis GO:0055082 180 0.036
metal ion transport GO:0030001 272 0.036
response to steroid hormone GO:0048545 80 0.036
Human Rat
nitrogen compound transport GO:0071705 191 0.036
protein maturation GO:0051604 233 0.036
Human
response to biotic stimulus GO:0009607 276 0.036
Rat
positive regulation of immune system process GO:0002684 283 0.035
cellular response to hormone stimulus GO:0032870 125 0.035
Human Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.035
Human Mouse Rat
regulation of immune response GO:0050776 201 0.035
Human
ion homeostasis GO:0050801 230 0.035
protein processing GO:0016485 226 0.034
Human
regulation of cytokine production GO:0001817 232 0.034
cation transport GO:0006812 331 0.034
cellular response to nitrogen compound GO:1901699 144 0.033
Human Mouse
isoquinoline alkaloid metabolic process GO:0033076 1 0.033
androgen biosynthetic process GO:0006702 3 0.033
response to genistein GO:0033595 1 0.033
positive regulation of cell migration GO:0030335 172 0.033
response to inorganic substance GO:0010035 127 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
regulation of secretion GO:0051046 194 0.032
lipid catabolic process GO:0016042 84 0.032
response to external biotic stimulus GO:0043207 261 0.032
Rat
regulation of cellular component movement GO:0051270 334 0.032
positive regulation of transport GO:0051050 336 0.032
regulation of cell motility GO:2000145 299 0.031
regulation of body fluid levels GO:0050878 99 0.031
regulation of secretion by cell GO:1903530 177 0.031
regulation of protein localization GO:0032880 296 0.031
negative regulation of multicellular organismal process GO:0051241 317 0.030
regulation of phospholipase c activating g protein coupled receptor signaling pathway GO:1900736 1 0.030
regulation of kinase activity GO:0043549 314 0.030
positive regulation of cell proliferation GO:0008284 301 0.030
thyroid hormone transport GO:0070327 2 0.030
quinone catabolic process GO:1901662 2 0.029
apoptotic signaling pathway GO:0097190 268 0.029
Human
positive regulation of protein phosphorylation GO:0001934 313 0.029
negative regulation of icosanoid secretion GO:0032304 2 0.029
intracellular protein transport GO:0006886 270 0.029
regulation of protein maturation GO:1903317 150 0.029
alpha amino acid metabolic process GO:1901605 72 0.029
Mouse
epoxygenase p450 pathway GO:0019373 3 0.028
carbohydrate derivative biosynthetic process GO:1901137 207 0.028
regulation of lipid metabolic process GO:0019216 96 0.028
cellular homeostasis GO:0019725 196 0.028
secretion by cell GO:0032940 226 0.028
oogenesis GO:0048477 2 0.028
cellular cation homeostasis GO:0030003 163 0.028
positive regulation of transferase activity GO:0051347 227 0.027
membrane organization GO:0061024 292 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
regulation of ion transport GO:0043269 189 0.027
protein catabolic process GO:0030163 325 0.027
retinoic acid biosynthetic process GO:0002138 2 0.027
nucleoside phosphate biosynthetic process GO:1901293 109 0.027
vesicle mediated transport GO:0016192 371 0.027
positive regulation of cell death GO:0010942 263 0.027
Human
cation homeostasis GO:0055080 189 0.027
nucleoside triphosphate metabolic process GO:0009141 422 0.027
terpenoid metabolic process GO:0006721 27 0.027
regulation of transferase activity GO:0051338 355 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
urate transport GO:0015747 3 0.026
inorganic ion transmembrane transport GO:0098660 231 0.026
cofactor metabolic process GO:0051186 87 0.026
neurological system process GO:0050877 163 0.026
single organism cellular localization GO:1902580 332 0.026
enzyme linked receptor protein signaling pathway GO:0007167 303 0.025
regulation of cell migration GO:0030334 289 0.025
oxidative demethylation GO:0070989 11 0.025
response to abiotic stimulus GO:0009628 336 0.025
biological adhesion GO:0022610 331 0.025
protein oligomerization GO:0051259 173 0.025
signal transduction by phosphorylation GO:0023014 297 0.025
growth GO:0040007 202 0.025
cellular protein catabolic process GO:0044257 261 0.025
glycosyl compound catabolic process GO:1901658 413 0.024
regulation of cell differentiation GO:0045595 393 0.024
Human
wound healing GO:0042060 115 0.024
negative regulation of cell death GO:0060548 345 0.024
single organism membrane organization GO:0044802 268 0.024
memory GO:0007613 3 0.024
naphthalene metabolic process GO:0018931 1 0.024
response to metal ion GO:0010038 84 0.024
regulation of proteolysis GO:0030162 293 0.024
Human
response to wounding GO:0009611 168 0.024
carboxylic acid transport GO:0046942 63 0.024
locomotory behavior GO:0007626 1 0.024
divalent inorganic cation homeostasis GO:0072507 136 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
organophosphate catabolic process GO:0046434 430 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
interspecies interaction between organisms GO:0044419 156 0.023
negative regulation of protein maturation GO:1903318 142 0.023
monosaccharide metabolic process GO:0005996 74 0.023
testosterone biosynthetic process GO:0061370 2 0.023
mitotic cell cycle GO:0000278 326 0.023
coagulation GO:0050817 78 0.023
tissue regeneration GO:0042246 3 0.023
monocarboxylic acid biosynthetic process GO:0072330 67 0.023
cellular metal ion homeostasis GO:0006875 146 0.023
protein targeting GO:0006605 187 0.023
organic hydroxy compound biosynthetic process GO:1901617 71 0.023
maintenance of location GO:0051235 112 0.022
Human
multi organism cellular process GO:0044764 156 0.022
regulation of protein processing GO:0070613 150 0.022
regulation of intracellular transport GO:0032386 195 0.022
cellular ion homeostasis GO:0006873 168 0.022
cell activation GO:0001775 213 0.022
response to phenylpropanoid GO:0080184 1 0.022
reactive oxygen species metabolic process GO:0072593 75 0.022
positive regulation of cellular component movement GO:0051272 181 0.022
nucleotide catabolic process GO:0009166 408 0.022
organic acid transport GO:0015849 65 0.022
viral process GO:0016032 146 0.022
segmentation GO:0035282 4 0.022
epithelial cell differentiation GO:0030855 141 0.022
Human
regulation of cell cycle GO:0051726 393 0.022
nervous system development GO:0007399 293 0.021
regulation of response to wounding GO:1903034 101 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
urea metabolic process GO:0019627 3 0.021
Mouse
dephosphorylation GO:0016311 209 0.021
response to growth factor GO:0070848 205 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
Human
cation transmembrane transport GO:0098655 238 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
protein localization to organelle GO:0033365 280 0.021
positive regulation of programmed cell death GO:0043068 249 0.021
Human
mitotic cell cycle process GO:1903047 286 0.021
phenylpropanoid metabolic process GO:0009698 3 0.021
cellular amide metabolic process GO:0043603 69 0.021
Mouse
alcohol metabolic process GO:0006066 114 0.021
toxin metabolic process GO:0009404 4 0.021
intracellular receptor signaling pathway GO:0030522 104 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
naphthalene containing compound metabolic process GO:0090420 1 0.021
regulation of mapk cascade GO:0043408 262 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
negative regulation of transport GO:0051051 176 0.020
negative regulation of protein processing GO:0010955 142 0.020
cellular organohalogen metabolic process GO:0090345 2 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
hemostasis GO:0007599 76 0.020
atp metabolic process GO:0046034 176 0.020
positive regulation of cell motility GO:2000147 177 0.020
response to estrogen GO:0043627 47 0.020
negative regulation of cell proliferation GO:0008285 228 0.020
Human
positive regulation of catabolic process GO:0009896 310 0.020
cytokine production GO:0001816 247 0.020
response to drug GO:0042493 81 0.020
Human
negative regulation of hydrolase activity GO:0051346 182 0.020
ribonucleotide catabolic process GO:0009261 405 0.020
regulation of cell cycle process GO:0010564 266 0.020
metal ion homeostasis GO:0055065 169 0.020
regulation of protein kinase activity GO:0045859 289 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
salivary gland morphogenesis GO:0007435 4 0.019
cell adhesion GO:0007155 325 0.019
regulation of homeostatic process GO:0032844 121 0.019
cell chemotaxis GO:0060326 112 0.019
protein ubiquitination GO:0016567 314 0.019
cellular divalent inorganic cation homeostasis GO:0072503 128 0.019
fatty acid omega oxidation GO:0010430 2 0.019
regulation of growth GO:0040008 165 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
carboxylic acid catabolic process GO:0046395 71 0.019
neuromuscular junction development GO:0007528 3 0.019
negative regulation of proteolysis GO:0045861 132 0.019
cell development GO:0048468 328 0.019
Human
regulation of nucleotide metabolic process GO:0006140 269 0.019
purine containing compound catabolic process GO:0072523 411 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
positive regulation of locomotion GO:0040017 186 0.019
response to cytokine GO:0034097 232 0.019
Human
positive regulation of cellular component organization GO:0051130 376 0.019
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.019
cellular carbohydrate metabolic process GO:0044262 84 0.019
Human
blastoderm segmentation GO:0007350 2 0.019
g protein coupled receptor signaling pathway GO:0007186 207 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
mapk cascade GO:0000165 288 0.018
cellular response to organic cyclic compound GO:0071407 127 0.018
Human Mouse Rat
uronic acid metabolic process GO:0006063 16 0.018
rhythmic behavior GO:0007622 2 0.018
blood coagulation GO:0007596 76 0.018
positive regulation of kinase activity GO:0033674 204 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
alkaloid catabolic process GO:0009822 3 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
glycerolipid metabolic process GO:0046486 107 0.018
cellular hormone metabolic process GO:0034754 41 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
coenzyme metabolic process GO:0006732 65 0.018
xenobiotic metabolic process GO:0006805 28 0.018
Human
cardiovascular system development GO:0072358 262 0.018
regulation of endopeptidase activity GO:0052548 170 0.018
Human
nucleocytoplasmic transport GO:0006913 176 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
regulation of protein transport GO:0051223 213 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
diterpenoid metabolic process GO:0016101 20 0.018
positive regulation of immune response GO:0050778 159 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
inorganic cation transmembrane transport GO:0098662 194 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
mitochondrion organization GO:0007005 156 0.017
myeloid cell differentiation GO:0030099 117 0.017
Human
negative regulation of cellular organohalogen metabolic process GO:0090349 1 0.017
cellular modified amino acid metabolic process GO:0006575 64 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
response to bacterium GO:0009617 144 0.017
Rat
negative regulation of cellular organofluorine metabolic process GO:0090350 1 0.017
positive regulation of plasminogen activation GO:0010756 3 0.017
reactive oxygen species biosynthetic process GO:1903409 4 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
response to fungus GO:0009620 4 0.017
response to nutrient levels GO:0031667 81 0.017
Human
regulation of multi organism process GO:0043900 157 0.017
negative regulation of protein modification process GO:0031400 200 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
regulation of cell adhesion GO:0030155 166 0.017
spermatid differentiation GO:0048515 4 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
inorganic anion transmembrane transport GO:0098661 47 0.016
cellular lipid catabolic process GO:0044242 65 0.016
cell growth GO:0016049 160 0.016
nuclear transport GO:0051169 179 0.016
actin filament based process GO:0030029 224 0.016
organic acid catabolic process GO:0016054 71 0.016
regulation of peptidase activity GO:0052547 180 0.016
Human
peptidyl tyrosine modification GO:0018212 170 0.016
positive regulation of developmental process GO:0051094 314 0.016
Human
nucleoside monophosphate metabolic process GO:0009123 191 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
limbic system development GO:0021761 3 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
cellular response to organonitrogen compound GO:0071417 124 0.016
Human Mouse
steroid biosynthetic process GO:0006694 46 0.016
negative regulation of response to external stimulus GO:0032102 83 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
activation of immune response GO:0002253 114 0.016
positive regulation of cytokine production GO:0001819 167 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
defense response to other organism GO:0098542 129 0.016
circadian behavior GO:0048512 2 0.016
drug catabolic process GO:0042737 10 0.016
Human
phylloquinone metabolic process GO:0042374 2 0.016
cellular calcium ion homeostasis GO:0006874 117 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
positive regulation of peptidyl serine phosphorylation of stat protein GO:0033141 3 0.015
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
Human
9 cis retinoic acid metabolic process GO:0042905 1 0.015
response to acid chemical GO:0001101 66 0.015
Human Mouse
viral life cycle GO:0019058 132 0.015
leukocyte migration GO:0050900 107 0.015
hormone catabolic process GO:0042447 4 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
immune effector process GO:0002252 159 0.015
positive regulation of protein transport GO:0051222 135 0.015
menaquinone metabolic process GO:0009233 3 0.015
regulation of cellular response to stress GO:0080135 244 0.015
endomembrane system organization GO:0010256 196 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
rho protein signal transduction GO:0007266 26 0.015
adult locomotory behavior GO:0008344 1 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
cellular glucuronidation GO:0052695 16 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
cellular response to lipid GO:0071396 127 0.015
Human Mouse Rat
vitamin k catabolic process GO:0042377 2 0.015
lipid transport GO:0006869 90 0.015
Human
reactive nitrogen species metabolic process GO:2001057 3 0.015
sequestering of metal ion GO:0051238 24 0.015
somatic muscle development GO:0007525 1 0.015
icosanoid catabolic process GO:1901523 2 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
small molecule catabolic process GO:0044282 92 0.015
associative learning GO:0008306 1 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
purine ribonucleotide biosynthetic process GO:0009152 79 0.014
regulation of cell growth GO:0001558 135 0.014
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.014
anatomical structure homeostasis GO:0060249 100 0.014
somatic stem cell maintenance GO:0035019 4 0.014
regulation of cellular organofluorine metabolic process GO:0090348 1 0.014
regulation of protein catabolic process GO:0042176 155 0.014
spermatid development GO:0007286 4 0.014
chemotaxis GO:0006935 157 0.014
protein localization to membrane GO:0072657 160 0.014
divalent inorganic cation transport GO:0072511 158 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
epithelium development GO:0060429 227 0.014
Human
chromatin organization GO:0006325 351 0.014
hindbrain development GO:0030902 3 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
negative regulation of locomotion GO:0040013 118 0.014
oocyte development GO:0048599 1 0.014
regulation of vasculature development GO:1901342 97 0.014
positive regulation of fibrinolysis GO:0051919 4 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
sequestering of calcium ion GO:0051208 17 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
ras protein signal transduction GO:0007265 73 0.014
lipid localization GO:0010876 106 0.014
Human
dna repair GO:0006281 198 0.014
nucleotide biosynthetic process GO:0009165 109 0.014
rna processing GO:0006396 255 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
aromatic amino acid family metabolic process GO:0009072 3 0.013
generation of precursor metabolites and energy GO:0006091 68 0.013
Human
ribose phosphate biosynthetic process GO:0046390 82 0.013
response to oxidative stress GO:0006979 121 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
behavior GO:0007610 112 0.013
calcium ion homeostasis GO:0055074 122 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
coumarin metabolic process GO:0009804 2 0.013
inner ear morphogenesis GO:0042472 4 0.013
circulatory system development GO:0072359 262 0.013
nucleoside catabolic process GO:0009164 408 0.013
endocytosis GO:0006897 159 0.013
demethylation GO:0070988 37 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
icosanoid metabolic process GO:0006690 35 0.013
tissue migration GO:0090130 119 0.013
ribonucleotide biosynthetic process GO:0009260 81 0.013
fatty acid derivative metabolic process GO:1901568 35 0.013
calcium ion transport GO:0006816 147 0.013
fatty acid biosynthetic process GO:0006633 46 0.013
cell morphogenesis GO:0000902 296 0.013
Human
positive regulation of apoptotic process GO:0043065 246 0.013
Human
negative regulation of organelle organization GO:0010639 126 0.013
anion transmembrane transport GO:0098656 76 0.013
regulation of lipid biosynthetic process GO:0046890 47 0.013
leukotriene catabolic process GO:0036100 2 0.013
regulation of viral process GO:0050792 103 0.013
vitamin e metabolic process GO:0042360 1 0.013
response to hypoxia GO:0001666 96 0.013
angiogenesis GO:0001525 147 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
positive regulation of secretion by cell GO:1903532 108 0.013
astrocyte differentiation GO:0048708 4 0.013
regulation of glial cell differentiation GO:0045685 3 0.013
midgut development GO:0007494 1 0.013
multicellular organismal homeostasis GO:0048871 67 0.013
cell cycle phase transition GO:0044770 173 0.013
leukocyte differentiation GO:0002521 98 0.013
Human
covalent chromatin modification GO:0016569 254 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
inflammatory response GO:0006954 79 0.012
response to extracellular stimulus GO:0009991 85 0.012
Human
cell projection organization GO:0030030 252 0.012
negative regulation of cell cycle GO:0045786 193 0.012
cell substrate adhesion GO:0031589 132 0.012
protein secretion GO:0009306 98 0.012
regulation of high density lipoprotein particle clearance GO:0010982 2 0.012
melanin metabolic process GO:0006582 1 0.012
purine containing compound biosynthetic process GO:0072522 88 0.012
interleukin 13 secretion GO:0072611 2 0.012
methylation GO:0032259 106 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
plasminogen activation GO:0031639 11 0.012
negative regulation of epithelial cell proliferation GO:0050680 48 0.012
Human
protein homooligomerization GO:0051260 100 0.012
response to radiation GO:0009314 151 0.012
regulation of transmembrane transport GO:0034762 139 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
Human
response to axon injury GO:0048678 1 0.012
response to oxygen levels GO:0070482 100 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
chromatin modification GO:0016568 298 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
response to decreased oxygen levels GO:0036293 96 0.012
long chain fatty acid metabolic process GO:0001676 30 0.012
negative regulation of immune system process GO:0002683 136 0.012
Human
cellular response to glucocorticoid stimulus GO:0071385 4 0.012
vasculature development GO:0001944 181 0.012
myoblast fusion GO:0007520 1 0.012
peripheral nervous system development GO:0007422 2 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.012
regulation of dna metabolic process GO:0051052 153 0.012
positive regulation of secretion GO:0051047 116 0.012
oocyte differentiation GO:0009994 2 0.012
mrna metabolic process GO:0016071 175 0.012
positive regulation of response to external stimulus GO:0032103 88 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
cytokine mediated signaling pathway GO:0019221 109 0.012
Human
regulation of neural precursor cell proliferation GO:2000177 4 0.012
prostate gland development GO:0030850 3 0.012
response to caffeine GO:0031000 3 0.012
divalent metal ion transport GO:0070838 152 0.012

NR1H4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.141
Human
inherited metabolic disorder DOID:655 242 0.121
amino acid metabolic disorder DOID:9252 50 0.038
acquired metabolic disease DOID:0060158 58 0.018
Human
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
sensory system disease DOID:0050155 203 0.017
nervous system disease DOID:863 431 0.017
central nervous system disease DOID:331 186 0.016
lipid metabolism disorder DOID:3146 26 0.016
steroid inherited metabolic disorder DOID:1701 9 0.016
organ system cancer DOID:0050686 164 0.016
immune system disease DOID:2914 155 0.015
musculoskeletal system disease DOID:17 223 0.014
Human
auditory system disease DOID:2742 53 0.014
hematopoietic system disease DOID:74 100 0.013
neurodegenerative disease DOID:1289 102 0.012
nonsyndromic deafness DOID:0050563 50 0.012