Homo sapiens

110 known processes

NR1I2

nuclear receptor subfamily 1, group I, member 2

(Aliases: PAR,ONR1,PAR1,PXR,BXR,SXR,PAR2,PARq,PRR,SAR)

NR1I2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 381 0.527
Human
oxidation reduction process GO:0055114 396 0.522
Human Fly
chemical homeostasis GO:0048878 306 0.518
Human Fly
response to xenobiotic stimulus GO:0009410 30 0.418
drug catabolic process GO:0042737 10 0.317
steroid metabolic process GO:0008202 94 0.276
Human
cellular amino acid metabolic process GO:0006520 116 0.274
cellular lipid metabolic process GO:0044255 303 0.254
monocarboxylic acid metabolic process GO:0032787 185 0.245
Human
carbohydrate metabolic process GO:0005975 207 0.195
Human Fly
cellular ketone metabolic process GO:0042180 80 0.182
Human
regulation of hormone levels GO:0010817 125 0.163
single organism carbohydrate metabolic process GO:0044723 193 0.158
Human Fly
cellular amine metabolic process GO:0044106 41 0.142
response to drug GO:0042493 81 0.126
amine metabolic process GO:0009308 44 0.118
immune response GO:0006955 307 0.115
Human
response to lipid GO:0033993 206 0.103
Human Zebrafish
alkaloid metabolic process GO:0009820 4 0.103
lipid catabolic process GO:0016042 84 0.101
fatty acid metabolic process GO:0006631 115 0.098
cation transport GO:0006812 331 0.097
transmembrane transport GO:0055085 399 0.094
alpha amino acid metabolic process GO:1901605 72 0.093
cellular response to endogenous stimulus GO:0071495 336 0.091
Human Zebrafish
response to oxygen containing compound GO:1901700 369 0.086
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.085
Human
sulfur compound metabolic process GO:0006790 101 0.084
response to organic cyclic compound GO:0014070 204 0.081
Human Zebrafish
regulation of immune response GO:0050776 201 0.080
Human
lipid modification GO:0030258 84 0.080
response to inorganic substance GO:0010035 127 0.074
cellular response to oxygen containing compound GO:1901701 276 0.073
Human
regulation of cellular amine metabolic process GO:0033238 11 0.073
organonitrogen compound biosynthetic process GO:1901566 200 0.072
response to hormone GO:0009725 175 0.072
Human Zebrafish
regulation of cellular amino acid metabolic process GO:0006521 6 0.071
regulation of response to external stimulus GO:0032101 222 0.070
organic hydroxy compound metabolic process GO:1901615 147 0.068
Human
regulation of ion transport GO:0043269 189 0.067
monosaccharide metabolic process GO:0005996 74 0.067
Fly
small molecule biosynthetic process GO:0044283 157 0.067
Human
cellular homeostasis GO:0019725 196 0.066
negative regulation of cell death GO:0060548 345 0.066
oxidative demethylation GO:0070989 11 0.066
ion homeostasis GO:0050801 230 0.064
ion transmembrane transport GO:0034220 338 0.063
negative regulation of catalytic activity GO:0043086 335 0.063
ribonucleoside monophosphate metabolic process GO:0009161 187 0.063
negative regulation of protein metabolic process GO:0051248 391 0.063
enzyme linked receptor protein signaling pathway GO:0007167 303 0.063
cofactor metabolic process GO:0051186 87 0.063
regulation of cellular component movement GO:0051270 334 0.062
positive regulation of programmed cell death GO:0043068 249 0.062
Human
positive regulation of phosphorylation GO:0042327 394 0.062
post embryonic development GO:0009791 2 0.062
regulation of proteolysis GO:0030162 293 0.062
Human
cellular divalent inorganic cation homeostasis GO:0072503 128 0.060
lipid biosynthetic process GO:0008610 177 0.058
Human
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.058
secretion GO:0046903 254 0.058
cellular response to xenobiotic stimulus GO:0071466 29 0.058
regulation of secretion GO:0051046 194 0.058
regulation of cell differentiation GO:0045595 393 0.056
Human
innate immune response GO:0045087 178 0.056
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.054
negative regulation of phosphate metabolic process GO:0045936 267 0.054
protein maturation GO:0051604 233 0.053
Human
alcohol metabolic process GO:0006066 114 0.053
protein processing GO:0016485 226 0.053
Human
regulation of ion transmembrane transport GO:0034765 132 0.053
carboxylic acid biosynthetic process GO:0046394 97 0.052
Human
maintenance of location GO:0051235 112 0.052
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.052
negative regulation of bile acid biosynthetic process GO:0070858 3 0.052
Human
regulation of locomotion GO:0040012 329 0.052
nitrogen compound transport GO:0071705 191 0.052
regulation of cell migration GO:0030334 289 0.051
positive regulation of transport GO:0051050 336 0.051
regulation of transferase activity GO:0051338 355 0.050
cytoplasmic transport GO:0016482 379 0.050
lipid homeostasis GO:0055088 39 0.050
Fly
cellular response to lipid GO:0071396 127 0.050
Human Zebrafish
regulation of lipid metabolic process GO:0019216 96 0.050
Human
reactive oxygen species metabolic process GO:0072593 75 0.050
cellular hormone metabolic process GO:0034754 41 0.049
determination of adult lifespan GO:0008340 2 0.049
regulation of establishment of protein localization GO:0070201 242 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
regeneration GO:0031099 4 0.048
negative regulation of apoptotic process GO:0043066 316 0.048
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.048
positive regulation of immune system process GO:0002684 283 0.047
coenzyme metabolic process GO:0006732 65 0.047
negative regulation of multicellular organismal process GO:0051241 317 0.046
activation of immune response GO:0002253 114 0.046
steroid biosynthetic process GO:0006694 46 0.046
Human
purine ribonucleoside metabolic process GO:0046128 437 0.045
regulation of protein localization GO:0032880 296 0.045
response to nitrogen compound GO:1901698 184 0.045
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.045
Human
regulation of transmembrane transport GO:0034762 139 0.044
purine nucleoside monophosphate metabolic process GO:0009126 186 0.044
response to organonitrogen compound GO:0010243 156 0.043
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.043
cellular chemical homeostasis GO:0055082 180 0.043
regulation of cytokine production GO:0001817 232 0.042
divalent inorganic cation homeostasis GO:0072507 136 0.042
cellular cation homeostasis GO:0030003 163 0.041
negative regulation of cell proliferation GO:0008285 228 0.041
Human
cation homeostasis GO:0055080 189 0.041
anion transport GO:0006820 161 0.041
defense response GO:0006952 315 0.041
Human
system process GO:0003008 349 0.041
Human
negative regulation of programmed cell death GO:0043069 321 0.041
lipid oxidation GO:0034440 33 0.040
naphthalene metabolic process GO:0018931 1 0.040
regulation of secretion by cell GO:1903530 177 0.040
monocarboxylic acid biosynthetic process GO:0072330 67 0.040
Human
actin filament based process GO:0030029 224 0.040
protein oligomerization GO:0051259 173 0.040
regulation of peptidase activity GO:0052547 180 0.039
Human
positive regulation of protein phosphorylation GO:0001934 313 0.039
response to abiotic stimulus GO:0009628 336 0.038
multicellular organismal aging GO:0010259 3 0.038
regulation of cell motility GO:2000145 299 0.038
organophosphate biosynthetic process GO:0090407 163 0.038
ornithine metabolic process GO:0006591 3 0.038
ribonucleoside triphosphate metabolic process GO:0009199 412 0.037
regulation of kinase activity GO:0043549 314 0.037
positive regulation of developmental process GO:0051094 314 0.037
Human
lipid localization GO:0010876 106 0.037
Human
nucleoside monophosphate metabolic process GO:0009123 191 0.037
metal ion transport GO:0030001 272 0.037
epoxygenase p450 pathway GO:0019373 3 0.037
regulation of nucleotide metabolic process GO:0006140 269 0.036
organic acid biosynthetic process GO:0016053 97 0.036
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.036
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
vasculature development GO:0001944 181 0.036
response to activity GO:0014823 0 0.036
organic hydroxy compound biosynthetic process GO:1901617 71 0.036
Human
cellular carbohydrate metabolic process GO:0044262 84 0.036
Human Fly
epithelial cell proliferation GO:0050673 128 0.035
Human
vesicle mediated transport GO:0016192 371 0.035
secretion by cell GO:0032940 226 0.035
cellular response to cytokine stimulus GO:0071345 181 0.035
Human
regulation of homeostatic process GO:0032844 121 0.035
negative regulation of phosphorylation GO:0042326 174 0.035
response to extracellular stimulus GO:0009991 85 0.035
Human Fly
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.034
regulation of synaptic plasticity GO:0048167 3 0.034
positive regulation of cell death GO:0010942 263 0.034
Human
xenobiotic metabolic process GO:0006805 28 0.034
sterol homeostasis GO:0055092 28 0.034
Fly
regulation of cytoplasmic transport GO:1903649 149 0.034
isoquinoline alkaloid metabolic process GO:0033076 1 0.033
cellular metal ion homeostasis GO:0006875 146 0.033
neurological system process GO:0050877 163 0.033
organic anion transport GO:0015711 103 0.033
positive regulation of cell proliferation GO:0008284 301 0.033
negative regulation of protein maturation GO:1903318 142 0.033
purine ribonucleotide biosynthetic process GO:0009152 79 0.033
positive regulation of immune response GO:0050778 159 0.033
amide transport GO:0042886 76 0.033
terpenoid metabolic process GO:0006721 27 0.033
negative regulation of locomotion GO:0040013 118 0.032
negative regulation of intracellular signal transduction GO:1902532 183 0.032
negative regulation of transport GO:0051051 176 0.032
regulation of protein kinase activity GO:0045859 289 0.032
nucleoside phosphate biosynthetic process GO:1901293 109 0.032
regulation of carbohydrate metabolic process GO:0006109 54 0.031
Human Fly
apoptotic signaling pathway GO:0097190 268 0.031
Human
positive regulation of transferase activity GO:0051347 227 0.031
drug metabolic process GO:0017144 19 0.031
glycerolipid metabolic process GO:0046486 107 0.031
exogenous drug catabolic process GO:0042738 8 0.031
negative regulation of protein processing GO:0010955 142 0.031
regulation of endopeptidase activity GO:0052548 170 0.031
Human
generation of precursor metabolites and energy GO:0006091 68 0.031
Human Fly
alkaloid catabolic process GO:0009822 3 0.031
signal transduction by phosphorylation GO:0023014 297 0.031
peptide transport GO:0015833 74 0.030
mitochondrion organization GO:0007005 156 0.030
nucleoside triphosphate metabolic process GO:0009141 422 0.030
mapk cascade GO:0000165 288 0.030
alpha ketoglutarate transport GO:0015742 1 0.030
negative regulation of protein modification process GO:0031400 200 0.030
negative regulation of cellular amine metabolic process GO:0033239 3 0.029
purine containing compound catabolic process GO:0072523 411 0.029
regulation of phospholipase c activating g protein coupled receptor signaling pathway GO:1900736 1 0.029
purine nucleotide biosynthetic process GO:0006164 84 0.029
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.029
Human
response to metal ion GO:0010038 84 0.029
small molecule catabolic process GO:0044282 92 0.029
organic acid transport GO:0015849 65 0.029
regulation of protein transport GO:0051223 213 0.029
memory GO:0007613 3 0.028
naphthalene containing compound metabolic process GO:0090420 1 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
negative regulation of cellular organohalogen metabolic process GO:0090349 1 0.028
atp metabolic process GO:0046034 176 0.028
purine containing compound biosynthetic process GO:0072522 88 0.028
single organism cellular localization GO:1902580 332 0.027
cellular calcium ion homeostasis GO:0006874 117 0.027
nucleotide catabolic process GO:0009166 408 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
immune effector process GO:0002252 159 0.027
protein catabolic process GO:0030163 325 0.027
isoprenoid metabolic process GO:0006720 39 0.027
response to nutrient levels GO:0031667 81 0.027
Human Fly
regulation of cell growth GO:0001558 135 0.027
negative regulation of developmental process GO:0051093 247 0.027
Human
intracellular receptor signaling pathway GO:0030522 104 0.027
peptidyl tyrosine phosphorylation GO:0018108 170 0.027
ribose phosphate biosynthetic process GO:0046390 82 0.027
regulation of apoptotic signaling pathway GO:2001233 175 0.026
protein homooligomerization GO:0051260 100 0.026
response to other organism GO:0051707 261 0.026
regulation of cellular component biogenesis GO:0044087 281 0.026
lipid transport GO:0006869 90 0.026
Human
intracellular protein transport GO:0006886 270 0.026
negative regulation of growth GO:0045926 97 0.026
response to external biotic stimulus GO:0043207 261 0.026
positive regulation of cellular component movement GO:0051272 181 0.026
locomotory behavior GO:0007626 1 0.026
cellular macromolecule catabolic process GO:0044265 380 0.026
hormone transport GO:0009914 68 0.026
regulation of intracellular transport GO:0032386 195 0.026
urate transport GO:0015747 3 0.026
nucleotide biosynthetic process GO:0009165 109 0.026
single organism membrane organization GO:0044802 268 0.026
epithelium migration GO:0090132 119 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
blood vessel development GO:0001568 172 0.026
female gamete generation GO:0007292 2 0.025
interspecies interaction between organisms GO:0044419 156 0.025
regulation of protein maturation GO:1903317 150 0.025
reactive oxygen species biosynthetic process GO:1903409 4 0.025
blood coagulation GO:0007596 76 0.025
long chain fatty acid metabolic process GO:0001676 30 0.025
9 cis retinoic acid metabolic process GO:0042905 1 0.025
organophosphate catabolic process GO:0046434 430 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
response to acid chemical GO:0001101 66 0.025
Human
response to low density lipoprotein particle GO:0055098 4 0.025
Human
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
protein targeting GO:0006605 187 0.025
epithelium development GO:0060429 227 0.025
Human
hexose metabolic process GO:0019318 55 0.025
Fly
cellular ion homeostasis GO:0006873 168 0.025
peptide secretion GO:0002790 51 0.024
positive regulation of protein kinase activity GO:0045860 190 0.024
regulation of mitochondrion organization GO:0010821 54 0.024
multi organism cellular process GO:0044764 156 0.024
cell activation GO:0001775 213 0.024
positive regulation of lipid metabolic process GO:0045834 50 0.024
regulation of response to wounding GO:1903034 101 0.024
carnitine transmembrane transport GO:1902603 3 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
glycolytic process GO:0006096 17 0.024
Human
negative regulation of cellular component movement GO:0051271 106 0.024
coagulation GO:0050817 78 0.024
defense response to other organism GO:0098542 129 0.024
mitotic cell cycle GO:0000278 326 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
response to cytokine GO:0034097 232 0.024
Human
sensory perception of pain GO:0019233 4 0.024
growth GO:0040007 202 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.023
cholesterol homeostasis GO:0042632 28 0.023
Fly
organic hydroxy compound transport GO:0015850 63 0.023
response to hypoxia GO:0001666 96 0.023
cell cell signaling GO:0007267 155 0.023
peptidyl tyrosine modification GO:0018212 170 0.023
response to growth factor GO:0070848 205 0.023
response to steroid hormone GO:0048545 80 0.023
Human Zebrafish
myeloid cell differentiation GO:0030099 117 0.023
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
regulation of cell cycle GO:0051726 393 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
regulation of smooth muscle cell proliferation GO:0048660 28 0.023
Human
positive regulation of mapk cascade GO:0043410 190 0.022
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.022
sensory perception GO:0007600 103 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
Human
regulation of mapk cascade GO:0043408 262 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
nucleocytoplasmic transport GO:0006913 176 0.022
negative regulation of icosanoid secretion GO:0032304 2 0.022
response to biotic stimulus GO:0009607 276 0.022
positive regulation of fibrinolysis GO:0051919 4 0.022
cellular response to oxidative stress GO:0034599 85 0.022
nuclear transport GO:0051169 179 0.022
carboxylic acid catabolic process GO:0046395 71 0.022
angiogenesis GO:0001525 147 0.022
divalent metal ion transport GO:0070838 152 0.022
metal ion homeostasis GO:0055065 169 0.022
negative regulation of protein phosphorylation GO:0001933 140 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.022
tissue migration GO:0090130 119 0.021
cellular protein catabolic process GO:0044257 261 0.021
response to oxidative stress GO:0006979 121 0.021
neuromuscular junction development GO:0007528 3 0.021
response to wounding GO:0009611 168 0.021
positive regulation of organelle organization GO:0010638 195 0.021
demethylation GO:0070988 37 0.021
oogenesis GO:0048477 2 0.021
g protein coupled receptor signaling pathway GO:0007186 207 0.021
carboxylic acid transport GO:0046942 63 0.021
viral process GO:0016032 146 0.021
cellular component morphogenesis GO:0032989 314 0.021
Human
regulation of hormone secretion GO:0046883 57 0.021
hormone secretion GO:0046879 65 0.021
cellular response to dna damage stimulus GO:0006974 379 0.021
negative regulation of kinase activity GO:0033673 106 0.021
purine nucleotide catabolic process GO:0006195 405 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
nuclear import GO:0051170 106 0.020
regulation of intracellular protein transport GO:0033157 123 0.020
segmentation GO:0035282 4 0.020
carbohydrate catabolic process GO:0016052 36 0.020
Human
negative regulation of hydrolase activity GO:0051346 182 0.020
i kappab kinase nf kappab signaling GO:0007249 166 0.020
activation of protein kinase activity GO:0032147 90 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
regulation of body fluid levels GO:0050878 99 0.020
circulatory system development GO:0072359 262 0.020
endodermal cell fate commitment GO:0001711 4 0.020
calcium ion homeostasis GO:0055074 122 0.020
membrane organization GO:0061024 292 0.020
sensory perception of smell GO:0007608 2 0.020
vitamin d receptor signaling pathway GO:0070561 4 0.020
Human
regulation of lipid biosynthetic process GO:0046890 47 0.020
Human
regulation of dna metabolic process GO:0051052 153 0.020
urea metabolic process GO:0019627 3 0.020
negative regulation of cell motility GO:2000146 104 0.020
regulation of protein processing GO:0070613 150 0.020
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.020
hemopoiesis GO:0030097 180 0.020
Human
blood vessel morphogenesis GO:0048514 162 0.020
regulation of transmembrane transporter activity GO:0022898 74 0.019
response to decreased oxygen levels GO:0036293 96 0.019
positive regulation of proteolysis GO:0045862 142 0.019
Human
purine ribonucleotide catabolic process GO:0009154 404 0.019
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.019
regulation of cellular response to stress GO:0080135 244 0.019
positive regulation of endopeptidase activity GO:0010950 84 0.019
Human
negative regulation of cell differentiation GO:0045596 171 0.019
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
regulation of nucleotide biosynthetic process GO:0030808 50 0.019
regulation of membrane potential GO:0042391 95 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
blastoderm segmentation GO:0007350 2 0.019
negative regulation of response to wounding GO:1903035 47 0.019
peptide hormone secretion GO:0030072 50 0.019
cellular response to hormone stimulus GO:0032870 125 0.019
Human Zebrafish
negative regulation of cellular organofluorine metabolic process GO:0090350 1 0.019
regulation of epithelial cell migration GO:0010632 93 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
positive regulation of kinase activity GO:0033674 204 0.019
cytokine production GO:0001816 247 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
regulation of oxidoreductase activity GO:0051341 43 0.019
Human
phospholipid metabolic process GO:0006644 99 0.018
sodium independent organic anion transport GO:0043252 2 0.018
response to nutrient GO:0007584 20 0.018
Human
nucleoside catabolic process GO:0009164 408 0.018
fatty acid biosynthetic process GO:0006633 46 0.018
cellular response to nitrogen compound GO:1901699 144 0.018
Human
salivary gland morphogenesis GO:0007435 4 0.018
regulation of growth GO:0040008 165 0.018
negative regulation of cell migration GO:0030336 102 0.018
dephosphorylation GO:0016311 209 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
regulation of cell cycle process GO:0010564 266 0.018
immune system development GO:0002520 195 0.018
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
xenobiotic transport GO:0042908 1 0.018
negative regulation of protein kinase activity GO:0006469 98 0.018
positive regulation of cytokine production GO:0001819 167 0.018
limbic system development GO:0021761 3 0.018
nervous system development GO:0007399 293 0.018
protein ubiquitination GO:0016567 314 0.018
cation transmembrane transport GO:0098655 238 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
vitamin k catabolic process GO:0042377 2 0.017
positive regulation of protein transport GO:0051222 135 0.017
energy homeostasis GO:0097009 3 0.017
zymogen activation GO:0031638 70 0.017
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.017
pyruvate metabolic process GO:0006090 26 0.017
Human
protein localization to organelle GO:0033365 280 0.017
response to oxygen levels GO:0070482 100 0.017
cell junction organization GO:0034330 79 0.017
cellular response to prostaglandin stimulus GO:0071379 4 0.017
cellular response to metal ion GO:0071248 43 0.017
positive regulation of dna metabolic process GO:0051054 73 0.017
positive regulation of ion transport GO:0043270 87 0.017
glucose metabolic process GO:0006006 45 0.017
Fly
mitotic cell cycle process GO:1903047 286 0.017
monoterpenoid metabolic process GO:0016098 6 0.017
cellular lipid catabolic process GO:0044242 65 0.017
cellular modified amino acid metabolic process GO:0006575 64 0.017
signal release GO:0023061 70 0.017
cellular response to organonitrogen compound GO:0071417 124 0.017
Human
cellular macromolecular complex assembly GO:0034622 324 0.017
cytosolic calcium ion homeostasis GO:0051480 89 0.017
single organism nuclear import GO:1902593 104 0.017
immune response activating signal transduction GO:0002757 90 0.017
positive regulation of cell differentiation GO:0045597 211 0.016
Human
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.016
Human
positive regulation of apoptotic process GO:0043065 246 0.016
Human
regulation of innate immune response GO:0045088 97 0.016
Human
positive regulation of cell development GO:0010720 92 0.016
regulation of ion transmembrane transporter activity GO:0032412 72 0.016
positive regulation of locomotion GO:0040017 186 0.016
single organism carbohydrate catabolic process GO:0044724 33 0.016
Human
negative regulation of cell cycle GO:0045786 193 0.016
regulation of lymphocyte activation GO:0051249 103 0.016
regulation of system process GO:0044057 101 0.016
actin mediated cell contraction GO:0070252 12 0.016
epithelial cell migration GO:0010631 119 0.016
somatic stem cell maintenance GO:0035019 4 0.016
arachidonic acid metabolic process GO:0019369 14 0.016
wound healing GO:0042060 115 0.016
regulation of reactive oxygen species metabolic process GO:2000377 41 0.016
positive regulation of peptidase activity GO:0010952 88 0.016
Human
organic acid catabolic process GO:0016054 71 0.016
immune response regulating signaling pathway GO:0002764 97 0.016
blastocyst development GO:0001824 3 0.016
negative regulation of cell growth GO:0030308 83 0.016
regulation of cell development GO:0060284 161 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
cytokine mediated signaling pathway GO:0019221 109 0.016
Human
leukocyte activation GO:0045321 164 0.016
sterol transport GO:0015918 39 0.016
protein autophosphorylation GO:0046777 123 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.016
Human
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.016
Human Fly
regulation of cellular organofluorine metabolic process GO:0090348 1 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
biological adhesion GO:0022610 331 0.016
positive regulation of catabolic process GO:0009896 310 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
extrinsic apoptotic signaling pathway GO:0097191 119 0.016
endocytosis GO:0006897 159 0.016
positive regulation of intracellular transport GO:0032388 104 0.016
ameboidal type cell migration GO:0001667 135 0.015
response to estrogen GO:0043627 47 0.015
inflammatory response GO:0006954 79 0.015
ras protein signal transduction GO:0007265 73 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
regulation of cell activation GO:0050865 125 0.015
negative regulation of proteolysis GO:0045861 132 0.015
actin filament based movement GO:0030048 17 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
regulation of leukocyte activation GO:0002694 115 0.015
regulation of transporter activity GO:0032409 82 0.015
detection of stimulus GO:0051606 85 0.015
hemostasis GO:0007599 76 0.015
establishment of tissue polarity GO:0007164 3 0.015
negative regulation of transferase activity GO:0051348 124 0.015
adult locomotory behavior GO:0008344 1 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
response to bacterium GO:0009617 144 0.015
divalent inorganic cation transport GO:0072511 158 0.015
endothelial cell proliferation GO:0001935 65 0.015
response to purine containing compound GO:0014074 40 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015

NR1I2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.197
Human
inherited metabolic disorder DOID:655 242 0.062
sensory system disease DOID:0050155 203 0.036
nervous system disease DOID:863 431 0.036
acquired metabolic disease DOID:0060158 58 0.030
Human
eye and adnexa disease DOID:1492 150 0.028
eye disease DOID:5614 149 0.027
retinal disease DOID:5679 118 0.027
disease of cellular proliferation DOID:14566 174 0.021
diabetes mellitus DOID:9351 31 0.020
Human
carbohydrate metabolism disease DOID:0050013 32 0.020
Human
glucose metabolism disease DOID:4194 32 0.020
Human
amino acid metabolic disorder DOID:9252 50 0.019
musculoskeletal system disease DOID:17 223 0.017
Human
cancer DOID:162 167 0.017
organ system cancer DOID:0050686 164 0.017
cardiovascular system disease DOID:1287 106 0.015
bone disease DOID:0080001 88 0.015
Human
connective tissue disease DOID:65 109 0.015
Human