Homo sapiens

0 known processes

NUP54

nucleoporin 54kDa

(Aliases: MGC13407)

NUP54 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transferase activity GO:0051338 355 0.219
negative regulation of cellular protein metabolic process GO:0032269 353 0.212
negative regulation of apoptotic process GO:0043066 316 0.179
ras protein signal transduction GO:0007265 73 0.173
small gtpase mediated signal transduction GO:0007264 78 0.162
negative regulation of cell proliferation GO:0008285 228 0.154
negative regulation of protein modification process GO:0031400 200 0.146
negative regulation of protein metabolic process GO:0051248 391 0.119
nuclear export GO:0051168 69 0.118
regulation of cell cycle GO:0051726 393 0.113
Worm
post embryonic development GO:0009791 2 0.106
Worm
regulation of protein kinase activity GO:0045859 289 0.102
locomotory behavior GO:0007626 1 0.100
negative regulation of cell death GO:0060548 345 0.094
negative regulation of intracellular signal transduction GO:1902532 183 0.083
negative regulation of protein phosphorylation GO:0001933 140 0.083
mapk cascade GO:0000165 288 0.083
endocytosis GO:0006897 159 0.080
Worm
regulation of protein serine threonine kinase activity GO:0071900 179 0.080
regulation of mapk cascade GO:0043408 262 0.078
amine metabolic process GO:0009308 44 0.077
negative regulation of catalytic activity GO:0043086 335 0.077
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.076
signal transduction by phosphorylation GO:0023014 297 0.075
cellular amine metabolic process GO:0044106 41 0.074
intracellular protein transport GO:0006886 270 0.071
immune response GO:0006955 307 0.070
negative regulation of phosphate metabolic process GO:0045936 267 0.065
negative regulation of phosphorylation GO:0042326 174 0.064
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.062
negative regulation of protein kinase activity GO:0006469 98 0.062
regulation of cellular amine metabolic process GO:0033238 11 0.061
enzyme linked receptor protein signaling pathway GO:0007167 303 0.060
negative regulation of phosphorus metabolic process GO:0010563 267 0.057
negative regulation of transferase activity GO:0051348 124 0.057
regulation of protein localization GO:0032880 296 0.056
regulation of ras protein signal transduction GO:0046578 155 0.054
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.053
nuclear transport GO:0051169 179 0.053
regulation of small gtpase mediated signal transduction GO:0051056 156 0.052
microtubule cytoskeleton organization GO:0000226 176 0.051
Worm
microtubule based process GO:0007017 210 0.048
Worm
negative regulation of multicellular organismal process GO:0051241 317 0.048
purine nucleoside catabolic process GO:0006152 398 0.048
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.047
rna processing GO:0006396 255 0.047
organophosphate biosynthetic process GO:0090407 163 0.047
single organism cellular localization GO:1902580 332 0.045
Worm
cellular amino acid metabolic process GO:0006520 116 0.045
cell aging GO:0007569 52 0.044
negative regulation of kinase activity GO:0033673 106 0.043
regulation of mitotic cell cycle GO:0007346 189 0.042
Worm
purine nucleoside monophosphate metabolic process GO:0009126 186 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
organelle localization GO:0051640 84 0.037
Worm
regulation of cell cycle process GO:0010564 266 0.037
negative regulation of cellular component organization GO:0051129 235 0.036
ribonucleotide catabolic process GO:0009261 405 0.036
memory GO:0007613 3 0.036
regulation of immune response GO:0050776 201 0.036
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.036
regulation of map kinase activity GO:0043405 108 0.035
actin filament based process GO:0030029 224 0.035
response to abiotic stimulus GO:0009628 336 0.035
regulation of locomotion GO:0040012 329 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
endomembrane system organization GO:0010256 196 0.033
regulation of response to external stimulus GO:0032101 222 0.033
innate immune response GO:0045087 178 0.033
cellular protein complex assembly GO:0043623 188 0.033
ribonucleoside catabolic process GO:0042454 406 0.032
protein export from nucleus GO:0006611 29 0.031
cellular ketone metabolic process GO:0042180 80 0.031
cellular component morphogenesis GO:0032989 314 0.030
negative regulation of map kinase activity GO:0043407 27 0.030
organelle assembly GO:0070925 176 0.030
nervous system development GO:0007399 293 0.029
purine nucleotide catabolic process GO:0006195 405 0.029
regulation of cell migration GO:0030334 289 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.027
regulation of proteolysis GO:0030162 293 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
cytoplasmic transport GO:0016482 379 0.027
negative regulation of cellular amine metabolic process GO:0033239 3 0.026
negative regulation of mapk cascade GO:0043409 56 0.026
modification dependent macromolecule catabolic process GO:0043632 212 0.026
protein ubiquitination GO:0016567 314 0.026
regulation of cellular component movement GO:0051270 334 0.026
actin cytoskeleton organization GO:0030036 207 0.026
multicellular organismal aging GO:0010259 3 0.026
cellular macromolecule catabolic process GO:0044265 380 0.025
negative regulation of immune system process GO:0002683 136 0.025
single organism membrane organization GO:0044802 268 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.025
protein catabolic process GO:0030163 325 0.024
protein maturation GO:0051604 233 0.024
regulation of multi organism process GO:0043900 157 0.024
secretion GO:0046903 254 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
positive regulation of cell death GO:0010942 263 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.023
cell division GO:0051301 168 0.023
Worm
positive regulation of organelle organization GO:0010638 195 0.023
negative regulation of cell cycle GO:0045786 193 0.023
microtubule organizing center organization GO:0031023 62 0.023
cellular protein catabolic process GO:0044257 261 0.023
embryo development GO:0009790 123 0.023
Worm
membrane organization GO:0061024 292 0.023
regulation of cell motility GO:2000145 299 0.023
cellular response to oxygen containing compound GO:1901701 276 0.022
protein modification by small protein conjugation GO:0032446 342 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
nitrogen compound transport GO:0071705 191 0.022
mitotic cell cycle GO:0000278 326 0.022
Worm
positive regulation of cell differentiation GO:0045597 211 0.022
lipid metabolic process GO:0006629 381 0.021
chromatin modification GO:0016568 298 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
defense response GO:0006952 315 0.021
anatomical structure formation involved in morphogenesis GO:0048646 284 0.021
vesicle mediated transport GO:0016192 371 0.021
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
positive regulation of cellular component organization GO:0051130 376 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
secretion by cell GO:0032940 226 0.021
protein modification by small protein removal GO:0070646 92 0.021
regulation of cellular response to stress GO:0080135 244 0.021
brain development GO:0007420 97 0.020
mitotic cell cycle process GO:1903047 286 0.020
Worm
cell morphogenesis GO:0000902 296 0.020
spermatid differentiation GO:0048515 4 0.020
synaptic vesicle localization GO:0097479 5 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
oogenesis GO:0048477 2 0.020
Worm
negative regulation of programmed cell death GO:0043069 321 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
spermatid development GO:0007286 4 0.019
protein processing GO:0016485 226 0.019
regulation of erbb signaling pathway GO:1901184 27 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
organophosphate catabolic process GO:0046434 430 0.019
cell cycle phase transition GO:0044770 173 0.019
positive regulation of immune system process GO:0002684 283 0.018
negative regulation of developmental process GO:0051093 247 0.018
positive regulation of catabolic process GO:0009896 310 0.018
purine containing compound catabolic process GO:0072523 411 0.018
cell adhesion GO:0007155 325 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
regulation of intracellular transport GO:0032386 195 0.018
positive regulation of cytokine production GO:0001819 167 0.018
determination of adult lifespan GO:0008340 2 0.018
nucleotide catabolic process GO:0009166 408 0.018
negative regulation of locomotion GO:0040013 118 0.018
embryonic epithelial tube formation GO:0001838 4 0.017
cytokine mediated signaling pathway GO:0019221 109 0.017
erbb signaling pathway GO:0038127 44 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
regulation of kinase activity GO:0043549 314 0.017
regulation of cell differentiation GO:0045595 393 0.017
Worm
system process GO:0003008 349 0.017
regulation of dna metabolic process GO:0051052 153 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
protein localization to nucleus GO:0034504 136 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
biological adhesion GO:0022610 331 0.017
glial cell migration GO:0008347 4 0.017
neuroblast proliferation GO:0007405 4 0.017
apoptotic signaling pathway GO:0097190 268 0.016
rna splicing GO:0008380 131 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
regulation of protein transport GO:0051223 213 0.016
cilium assembly GO:0042384 63 0.016
compound eye development GO:0048749 1 0.016
response to oxygen containing compound GO:1901700 369 0.016
adult locomotory behavior GO:0008344 1 0.016
positive regulation of cell division GO:0051781 59 0.016
regulation of protein catabolic process GO:0042176 155 0.016
centrosome cycle GO:0007098 32 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
cellular lipid metabolic process GO:0044255 303 0.016
nucleobase containing compound transport GO:0015931 51 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
negative regulation of organelle organization GO:0010639 126 0.015
regulation of defense response GO:0031347 154 0.015
cell projection assembly GO:0030031 126 0.015
cell activation GO:0001775 213 0.015
ribonucleoprotein complex biogenesis GO:0022613 116 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
cytokinesis GO:0000910 96 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
negative regulation of multi organism process GO:0043901 92 0.015
wound healing GO:0042060 115 0.014
segmentation GO:0035282 4 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 11 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
protein localization to organelle GO:0033365 280 0.014
regeneration GO:0031099 4 0.014
leukocyte activation GO:0045321 164 0.014
regulation of chromosome organization GO:0033044 103 0.014
negative regulation of transport GO:0051051 176 0.014
maintenance of location GO:0051235 112 0.014
epithelial cell proliferation GO:0050673 128 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
protein localization to membrane GO:0072657 160 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
vesicle localization GO:0051648 26 0.014
negative regulation of defense response GO:0031348 47 0.014
positive regulation of innate immune response GO:0045089 79 0.014
regulation of innate immune response GO:0045088 97 0.014
single organism cell adhesion GO:0098602 179 0.013
positive regulation of immune response GO:0050778 159 0.013
wnt signaling pathway GO:0016055 156 0.013
protein homooligomerization GO:0051260 100 0.013
defense response to other organism GO:0098542 129 0.013
cell projection organization GO:0030030 252 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
positive regulation of cell cycle GO:0045787 140 0.013
Worm
regulation of cytokine production GO:0001817 232 0.013
cell development GO:0048468 328 0.013
Worm
cellular response to cytokine stimulus GO:0071345 181 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
cell fate determination GO:0001709 3 0.013
oxidation reduction process GO:0055114 396 0.013
chromatin organization GO:0006325 351 0.013
neurotransmitter secretion GO:0007269 4 0.013
female gamete generation GO:0007292 2 0.013
Worm
ameboidal type cell migration GO:0001667 135 0.013
response to cytokine GO:0034097 232 0.013
negative regulation of intracellular transport GO:0032387 60 0.013
neuromuscular junction development GO:0007528 3 0.013
response to other organism GO:0051707 261 0.013
mrna metabolic process GO:0016071 175 0.013
alcohol metabolic process GO:0006066 114 0.013
glycerolipid metabolic process GO:0046486 107 0.013
cellular homeostasis GO:0019725 196 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
mitotic sister chromatid separation GO:0051306 18 0.012
peripheral nervous system development GO:0007422 2 0.012
glycoprotein metabolic process GO:0009100 110 0.012
negative regulation of protein maturation GO:1903318 142 0.012
response to virus GO:0009615 126 0.012
regulation of proteasomal protein catabolic process GO:0061136 87 0.012
oocyte development GO:0048599 1 0.012
cell part morphogenesis GO:0032990 137 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
regulation of nuclear division GO:0051783 65 0.012
cell projection morphogenesis GO:0048858 129 0.012
hindbrain development GO:0030902 3 0.012
nucleoside catabolic process GO:0009164 408 0.012
cilium morphogenesis GO:0060271 75 0.012
regulation of myeloid cell differentiation GO:0045637 81 0.012
reproductive process GO:0022414 106 0.012
Worm
negative regulation of protein processing GO:0010955 142 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
endothelial cell proliferation GO:0001935 65 0.012
regulation of odontogenesis GO:0042481 4 0.012
central nervous system development GO:0007417 123 0.012
response to hormone GO:0009725 175 0.012
regulation of mitosis GO:0007088 63 0.012
regulation of cell division GO:0051302 116 0.011
Worm
negative regulation of cell motility GO:2000146 104 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
atp catabolic process GO:0006200 157 0.011
t cell differentiation in thymus GO:0033077 4 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
chromosome segregation GO:0007059 114 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
protein oligomerization GO:0051259 173 0.011
neural tube formation GO:0001841 3 0.011
cell cycle arrest GO:0007050 71 0.011
cellular response to lipid GO:0071396 127 0.011
neurological system process GO:0050877 163 0.011
positive regulation of defense response GO:0031349 87 0.011
synaptic vesicle endocytosis GO:0048488 2 0.011
cilium organization GO:0044782 68 0.011
dephosphorylation GO:0016311 209 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
negative regulation of proteolysis GO:0045861 132 0.011
golgi to vacuole transport GO:0006896 3 0.011
tissue migration GO:0090130 119 0.011
epidermal growth factor receptor signaling pathway GO:0007173 39 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
negative regulation of dna metabolic process GO:0051053 57 0.011
thymus development GO:0048538 3 0.011
response to organic cyclic compound GO:0014070 204 0.011
response to growth factor GO:0070848 205 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
immune system development GO:0002520 195 0.011
positive regulation of developmental process GO:0051094 314 0.011
Worm
establishment of protein localization to membrane GO:0090150 121 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
phospholipid metabolic process GO:0006644 99 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
myosin filament assembly GO:0031034 2 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
positive regulation of transport GO:0051050 336 0.011
lymphocyte activation GO:0046649 133 0.010
meiosis i GO:0007127 4 0.010
negative regulation of response to external stimulus GO:0032102 83 0.010
positive regulation of synaptic transmission GO:0050806 4 0.010
immune effector process GO:0002252 159 0.010
canonical wnt signaling pathway GO:0060070 116 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
positive regulation of proteolysis GO:0045862 142 0.010
receptor mediated endocytosis GO:0006898 84 0.010
Worm
regulation of peptidase activity GO:0052547 180 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
ribonucleoside monophosphate catabolic process GO:0009158 158 0.010
protein targeting GO:0006605 187 0.010
glycoprotein biosynthetic process GO:0009101 91 0.010
negative regulation of cellular component movement GO:0051271 106 0.010
response to wounding GO:0009611 168 0.010

NUP54 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.111
neurodegenerative disease DOID:1289 102 0.111
nervous system disease DOID:863 431 0.111
synucleinopathy DOID:0050890 22 0.094
disease of metabolism DOID:0014667 295 0.047
inherited metabolic disorder DOID:655 242 0.043
sensory system disease DOID:0050155 203 0.012
musculoskeletal system disease DOID:17 223 0.012
disease of cellular proliferation DOID:14566 174 0.010