Homo sapiens

26 known processes

NXF1

nuclear RNA export factor 1

(Aliases: TAP,MEX67,DKFZp667O0311)

NXF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna transport GO:0051028 30 0.998
establishment of rna localization GO:0051236 39 0.998
rna transport GO:0050658 39 0.997
nucleic acid transport GO:0050657 39 0.995
rna export from nucleus GO:0006405 33 0.993
nucleobase containing compound transport GO:0015931 51 0.990
rna localization GO:0006403 41 0.978
nuclear pore organization GO:0006999 10 0.969
nucleus organization GO:0006997 28 0.967
regulation of nucleocytoplasmic transport GO:0046822 98 0.947
nitrogen compound transport GO:0071705 191 0.926
nucleocytoplasmic transport GO:0006913 176 0.917
post embryonic development GO:0009791 2 0.893
cytoplasmic transport GO:0016482 379 0.847
blastoderm segmentation GO:0007350 2 0.743
nuclear pore complex assembly GO:0051292 7 0.701
regulation of cytoplasmic transport GO:1903649 149 0.670
cellular macromolecular complex assembly GO:0034622 324 0.665
mrna export from nucleus GO:0006406 29 0.654
anterior posterior axis specification GO:0009948 2 0.654
intracellular protein transport GO:0006886 270 0.620
female gamete generation GO:0007292 2 0.576
segmentation GO:0035282 4 0.570
regulation of meiotic cell cycle GO:0051445 4 0.563
pore complex assembly GO:0046931 9 0.562
protein import into nucleus GO:0006606 104 0.555
protein localization to organelle GO:0033365 280 0.552
regulation of intracellular transport GO:0032386 195 0.545
nuclear export GO:0051168 69 0.529
regulation of cell cycle GO:0051726 393 0.514
anterior posterior axis specification embryo GO:0008595 2 0.510
vesicle mediated transport GO:0016192 371 0.499
embryo development GO:0009790 123 0.496
Worm
tripartite regional subdivision GO:0007351 2 0.453
nuclear transport GO:0051169 179 0.445
cellular protein complex assembly GO:0043623 188 0.409
engulfment of apoptotic cell GO:0043652 2 0.409
single organism cellular localization GO:1902580 332 0.397
regulation of nucleobase containing compound transport GO:0032239 7 0.371
g1 s transition of mitotic cell cycle GO:0000082 78 0.363
rna splicing GO:0008380 131 0.357
embryo development ending in birth or egg hatching GO:0009792 34 0.353
Worm
negative regulation of multicellular organismal process GO:0051241 317 0.348
oogenesis GO:0048477 2 0.332
protein export from nucleus GO:0006611 29 0.299
regulation of mrna splicing via spliceosome GO:0048024 32 0.293
regulation of mrna processing GO:0050684 48 0.272
endocytosis GO:0006897 159 0.271
regulation of meiosis GO:0040020 3 0.262
regulation of mrna export from nucleus GO:0010793 3 0.257
protein localization to nucleus GO:0034504 136 0.256
oocyte differentiation GO:0009994 2 0.251
neuromuscular junction development GO:0007528 3 0.249
regulation of mitotic cell cycle GO:0007346 189 0.244
protein targeting to nucleus GO:0044744 104 0.234
protein targeting GO:0006605 187 0.220
male meiosis GO:0007140 1 0.213
regulation of mapk cascade GO:0043408 262 0.211
regulation of rna splicing GO:0043484 62 0.198
reproductive process GO:0022414 106 0.193
receptor mediated endocytosis GO:0006898 84 0.169
negative regulation of transport GO:0051051 176 0.152
response to external biotic stimulus GO:0043207 261 0.149
negative regulation of growth GO:0045926 97 0.148
nuclear import GO:0051170 106 0.142
mrna metabolic process GO:0016071 175 0.140
Fly
rna interference GO:0016246 4 0.137
mitotic cell cycle phase transition GO:0044772 162 0.135
response to bacterium GO:0009617 144 0.124
regulation of cell cycle process GO:0010564 266 0.124
cell division GO:0051301 168 0.120
mitotic cell cycle GO:0000278 326 0.116
nervous system development GO:0007399 293 0.115
embryonic axis specification GO:0000578 5 0.113
regulation of mrna metabolic process GO:1903311 53 0.113
response to biotic stimulus GO:0009607 276 0.110
protein import GO:0017038 130 0.106
regulation of cell cycle g1 s phase transition GO:1902806 42 0.101
oocyte development GO:0048599 1 0.101
regulation of autophagy GO:0010506 52 0.100
microtubule organizing center organization GO:0031023 62 0.096
regulation of mitotic cell cycle phase transition GO:1901990 118 0.095
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.093
multicellular organismal aging GO:0010259 3 0.093
sex differentiation GO:0007548 45 0.092
response to heat GO:0009408 21 0.092
single organism nuclear import GO:1902593 104 0.089
organelle fission GO:0048285 149 0.087
regulation of protein localization GO:0032880 296 0.085
ribonucleoside triphosphate metabolic process GO:0009199 412 0.083
gonad development GO:0008406 34 0.083
establishment of protein localization to organelle GO:0072594 172 0.080
purine nucleoside triphosphate catabolic process GO:0009146 392 0.079
negative regulation of developmental process GO:0051093 247 0.078
negative regulation of locomotion GO:0040013 118 0.078
mrna splicing via spliceosome GO:0000398 89 0.077
centrosome organization GO:0051297 58 0.077
regulation of cellular response to stress GO:0080135 244 0.077
microtubule based process GO:0007017 210 0.075
dna replication GO:0006260 116 0.074
meiosis i GO:0007127 4 0.073
response to other organism GO:0051707 261 0.072
negative regulation of cell cycle GO:0045786 193 0.072
rna splicing via transesterification reactions GO:0000375 90 0.071
rna processing GO:0006396 255 0.070
Fly
signal transduction by phosphorylation GO:0023014 297 0.067
enzyme linked receptor protein signaling pathway GO:0007167 303 0.066
cell cycle g1 s phase transition GO:0044843 80 0.066
nuclear division GO:0000280 128 0.066
locomotory behavior GO:0007626 1 0.064
negative regulation of cell differentiation GO:0045596 171 0.064
mrna processing GO:0006397 133 0.058
Fly
negative regulation of protein metabolic process GO:0051248 391 0.057
cellular response to heat GO:0034605 14 0.057
negative regulation of epidermal cell differentiation GO:0045605 4 0.057
regulation of defense response GO:0031347 154 0.056
autophagy GO:0006914 88 0.056
posttranscriptional gene silencing by rna GO:0035194 25 0.054
negative regulation of catalytic activity GO:0043086 335 0.054
negative regulation of cytoplasmic transport GO:1903650 46 0.052
negative regulation of cellular component organization GO:0051129 235 0.051
negative regulation of phosphate metabolic process GO:0045936 267 0.051
stem cell differentiation GO:0048863 93 0.051
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.051
regulation of gene expression epigenetic GO:0040029 73 0.051
epithelial cell proliferation involved in lung morphogenesis GO:0060502 3 0.050
mapk cascade GO:0000165 288 0.050
cellular component disassembly GO:0022411 92 0.048
negative regulation of developmental growth GO:0048640 10 0.047
cellular response to organic cyclic compound GO:0071407 127 0.046
nucleoside monophosphate metabolic process GO:0009123 191 0.046
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.046
regulation of immune response GO:0050776 201 0.044
regulation of innate immune response GO:0045088 97 0.043
defense response to other organism GO:0098542 129 0.043
small molecule biosynthetic process GO:0044283 157 0.042
female sex determination GO:0030237 1 0.041
cell development GO:0048468 328 0.041
male genitalia development GO:0030539 1 0.040
synaptic vesicle localization GO:0097479 5 0.039
response to organic cyclic compound GO:0014070 204 0.039
membrane organization GO:0061024 292 0.039
dna templated transcription elongation GO:0006354 25 0.038
lipid metabolic process GO:0006629 381 0.038
sex determination GO:0007530 3 0.037
regulation of purine nucleotide catabolic process GO:0033121 205 0.036
reproductive structure development GO:0048608 55 0.036
heart development GO:0007507 95 0.036
ribonucleoside triphosphate catabolic process GO:0009203 391 0.035
negative regulation of phosphorus metabolic process GO:0010563 267 0.035
purine nucleoside monophosphate metabolic process GO:0009126 186 0.035
regulation of protein targeting GO:1903533 91 0.035
defense response GO:0006952 315 0.034
cell cycle phase transition GO:0044770 173 0.034
nucleoside catabolic process GO:0009164 408 0.034
positive regulation of developmental process GO:0051094 314 0.033
defense response to bacterium GO:0042742 63 0.033
gene silencing by rna GO:0031047 26 0.033
reproductive system development GO:0061458 56 0.032
regulation of nuclear division GO:0051783 65 0.032
negative regulation of intracellular transport GO:0032387 60 0.031
regulation of cell differentiation GO:0045595 393 0.031
small gtpase mediated signal transduction GO:0007264 78 0.031
positive regulation of epithelial cell proliferation GO:0050679 65 0.031
nucleotide catabolic process GO:0009166 408 0.030
regulation of rna export from nucleus GO:0046831 6 0.030
posttranscriptional gene silencing GO:0016441 25 0.030
regulation of cell cycle phase transition GO:1901987 126 0.030
negative regulation of defense response GO:0031348 47 0.030
memory GO:0007613 3 0.029
response to temperature stimulus GO:0009266 22 0.029
anatomical structure formation involved in morphogenesis GO:0048646 284 0.029
growth GO:0040007 202 0.029
cellular amine metabolic process GO:0044106 41 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
mitotic cell cycle process GO:1903047 286 0.029
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.029
determination of adult lifespan GO:0008340 2 0.029
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 2 0.028
regulation of synapse assembly GO:0051963 5 0.028
regulation of intracellular protein transport GO:0033157 123 0.027
negative regulation of keratinocyte differentiation GO:0045617 3 0.027
response to abiotic stimulus GO:0009628 336 0.027
morphogenesis of embryonic epithelium GO:0016331 4 0.027
chromatin organization GO:0006325 351 0.027
viral life cycle GO:0019058 132 0.027
regulation of protein transport GO:0051223 213 0.027
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.026
negative regulation of immune system process GO:0002683 136 0.026
positive regulation of hydrolase activity GO:0051345 331 0.026
apoptotic cell clearance GO:0043277 12 0.026
interspecies interaction between organisms GO:0044419 156 0.026
ribonucleotide catabolic process GO:0009261 405 0.025
localization within membrane GO:0051668 14 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
positive regulation of dna templated transcription elongation GO:0032786 18 0.024
cardiovascular system development GO:0072358 262 0.024
ribonucleoside monophosphate catabolic process GO:0009158 158 0.024
positive regulation of cell death GO:0010942 263 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
protein modification by small protein removal GO:0070646 92 0.023
cellular homeostasis GO:0019725 196 0.022
organonitrogen compound biosynthetic process GO:1901566 200 0.022
spliceosomal complex assembly GO:0000245 17 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
regulation of response to wounding GO:1903034 101 0.022
peripheral nervous system development GO:0007422 2 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
gene silencing GO:0016458 49 0.021
adult locomotory behavior GO:0008344 1 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
negative regulation of nervous system development GO:0051961 28 0.021
negative regulation of mapk cascade GO:0043409 56 0.021
epithelium development GO:0060429 227 0.021
phagocytosis GO:0006909 42 0.020
regulation of dna templated transcription elongation GO:0032784 23 0.020
purine nucleoside monophosphate catabolic process GO:0009128 158 0.020
organ morphogenesis GO:0009887 147 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
microtubule cytoskeleton organization GO:0000226 176 0.020
regulation of nervous system development GO:0051960 88 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.020
neural tube formation GO:0001841 3 0.020
regulation of map kinase activity GO:0043405 108 0.020
atp metabolic process GO:0046034 176 0.020
regulation of cellular ketone metabolic process GO:0010565 50 0.020
spermatid differentiation GO:0048515 4 0.019
osteoblast differentiation GO:0001649 92 0.019
organophosphate catabolic process GO:0046434 430 0.019
regulation of multi organism process GO:0043900 157 0.019
protein complex localization GO:0031503 31 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
development of primary sexual characteristics GO:0045137 35 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.018
regulation of growth rate GO:0040009 1 0.018
regulation of protein complex disassembly GO:0043244 28 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
stress activated protein kinase signaling cascade GO:0031098 94 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
hemopoiesis GO:0030097 180 0.017
regulation of oocyte development GO:0060281 1 0.017
atp catabolic process GO:0006200 157 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.017
reproduction GO:0000003 63 0.017
negative regulation of viral genome replication GO:0045071 35 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
amine metabolic process GO:0009308 44 0.017
smad protein import into nucleus GO:0007184 13 0.016
male gamete generation GO:0048232 22 0.016
somitogenesis GO:0001756 2 0.016
regulation of epidermis development GO:0045682 19 0.016
embryonic pattern specification GO:0009880 5 0.016
developmental process involved in reproduction GO:0003006 66 0.016
regulation of developmental growth GO:0048638 30 0.016
regulation of protein serine threonine kinase activity GO:0071900 179 0.016
stem cell development GO:0048864 69 0.016
erbb signaling pathway GO:0038127 44 0.016
negative regulation of cell cycle process GO:0010948 121 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
multicellular organismal reproductive process GO:0048609 40 0.015
nls bearing protein import into nucleus GO:0006607 2 0.015
ras protein signal transduction GO:0007265 73 0.015
immune response GO:0006955 307 0.015
branch elongation of an epithelium GO:0060602 3 0.015
cellular ketone metabolic process GO:0042180 80 0.015
regulation of cell maturation GO:1903429 3 0.015
defense response to fungus GO:0050832 4 0.015
chromatin modification GO:0016568 298 0.015
multi organism reproductive process GO:0044703 54 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
dna conformation change GO:0071103 113 0.014
dna recombination GO:0006310 77 0.014
regulation of viral genome replication GO:0045069 48 0.014
negative regulation of transferase activity GO:0051348 124 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
negative regulation of innate immune response GO:0045824 18 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
cellular ion homeostasis GO:0006873 168 0.014
dna packaging GO:0006323 77 0.014
vasculature development GO:0001944 181 0.014
negative regulation of multi organism process GO:0043901 92 0.014
leukocyte mediated immunity GO:0002443 59 0.014
nucleotide excision repair GO:0006289 31 0.014
regeneration GO:0031099 4 0.014
ossification GO:0001503 121 0.014
inorganic ion transmembrane transport GO:0098660 231 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
regulation of epithelial cell proliferation GO:0050678 113 0.013
sulfur compound biosynthetic process GO:0044272 38 0.013
regulation of atp metabolic process GO:1903578 29 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
circulatory system development GO:0072359 262 0.013
dna repair GO:0006281 198 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
inflammatory response GO:0006954 79 0.013
regulation of growth GO:0040008 165 0.013
regulation of myeloid cell differentiation GO:0045637 81 0.013
viral process GO:0016032 146 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
angiogenesis GO:0001525 147 0.013
regulation of kinase activity GO:0043549 314 0.013
dosage compensation GO:0007549 3 0.013
positive regulation of protein kinase activity GO:0045860 190 0.012
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
response to molecule of bacterial origin GO:0002237 82 0.012
macromolecular complex disassembly GO:0032984 60 0.012
epithelial cell proliferation GO:0050673 128 0.012
cellular macromolecule catabolic process GO:0044265 380 0.012
negative regulation of cell death GO:0060548 345 0.012
aging GO:0007568 66 0.012
regulation of proteolysis GO:0030162 293 0.012
circadian sleep wake cycle GO:0042745 2 0.012
macromolecule deacylation GO:0098732 41 0.012
cellular amino acid metabolic process GO:0006520 116 0.012
immune system development GO:0002520 195 0.012
regulation of cell development GO:0060284 161 0.012
muscle system process GO:0003012 81 0.012
myosin filament assembly GO:0031034 2 0.012
protein autophosphorylation GO:0046777 123 0.012
blastocyst development GO:0001824 3 0.012
cellular protein complex disassembly GO:0043624 36 0.012
primary neural tube formation GO:0014020 3 0.012
sulfur compound metabolic process GO:0006790 101 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.011
regionalization GO:0003002 29 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
regulation of isotype switching GO:0045191 2 0.011
mitotic nuclear division GO:0007067 119 0.011
regulation of epithelial cell proliferation involved in lung morphogenesis GO:2000794 2 0.011
adaptive immune response GO:0002250 49 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
positive regulation of cellular amine metabolic process GO:0033240 7 0.011
response to drug GO:0042493 81 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
cellular biogenic amine metabolic process GO:0006576 34 0.011
ribonucleoprotein complex subunit organization GO:0071826 81 0.011
regulation of protein kinase activity GO:0045859 289 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.011
nuclear pore distribution GO:0031081 1 0.011
wound healing GO:0042060 115 0.011
response to fungus GO:0009620 4 0.011
gamete generation GO:0007276 25 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
regulation of locomotion GO:0040012 329 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.010
toxin transport GO:1901998 4 0.010
chordate embryonic development GO:0043009 34 0.010
stress activated mapk cascade GO:0051403 93 0.010
negative regulation of mrna metabolic process GO:1903312 15 0.010
regulation of cell division GO:0051302 116 0.010
protein catabolic process GO:0030163 325 0.010
histone modification GO:0016570 251 0.010
regulation of chromatin assembly GO:0010847 2 0.010
response to oxygen levels GO:0070482 100 0.010
mitochondrion organization GO:0007005 156 0.010
rhythmic behavior GO:0007622 2 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
positive regulation of mapk cascade GO:0043410 190 0.010
nucleus localization GO:0051647 1 0.010
pattern specification process GO:0007389 43 0.010
epidermal cell differentiation GO:0009913 45 0.010
protein localization to membrane GO:0072657 160 0.010

NXF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.169
disease of cellular proliferation DOID:14566 174 0.169
organ system cancer DOID:0050686 164 0.169
muscular disease DOID:0080000 114 0.130
musculoskeletal system disease DOID:17 223 0.130
myeloid leukemia DOID:8692 18 0.102
immune system cancer DOID:0060083 36 0.102
acute myeloid leukemia DOID:9119 17 0.102
hematologic cancer DOID:2531 36 0.102
leukemia DOID:1240 21 0.102
synucleinopathy DOID:0050890 22 0.045
central nervous system disease DOID:331 186 0.045
neurodegenerative disease DOID:1289 102 0.045
nervous system disease DOID:863 431 0.045
myopathy DOID:423 104 0.040
muscular dystrophy DOID:9884 51 0.040
muscle tissue disease DOID:66 113 0.040