Homo sapiens

0 known processes

ORC1

origin recognition complex, subunit 1

(Aliases: ORC1L,PARC1,HSORC1)

ORC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication initiation GO:0006270 6 1.000
Fly
dna dependent dna replication GO:0006261 44 0.997
Fly
dna replication GO:0006260 116 0.997
Fly
chromatin organization GO:0006325 351 0.925
post embryonic development GO:0009791 2 0.893
Worm
protein dna complex subunit organization GO:0071824 80 0.882
mitotic sister chromatid segregation GO:0000070 53 0.842
protein dna complex assembly GO:0065004 64 0.804
sister chromatid segregation GO:0000819 54 0.742
mitotic sister chromatid separation GO:0051306 18 0.693
regulation of dna dependent dna replication initiation GO:0030174 3 0.670
positive regulation of mitotic cell cycle GO:0045931 60 0.626
dna unwinding involved in dna replication GO:0006268 2 0.615
mitotic nuclear division GO:0007067 119 0.611
mitotic cell cycle phase transition GO:0044772 162 0.609
metaphase anaphase transition of cell cycle GO:0044784 21 0.592
regulation of mitosis GO:0007088 63 0.574
double strand break repair GO:0006302 101 0.568
g2 dna damage checkpoint GO:0031572 26 0.532
recombinational repair GO:0000725 50 0.514
mitotic cell cycle GO:0000278 326 0.493
neutral lipid catabolic process GO:0046461 12 0.493
dna conformation change GO:0071103 113 0.473
covalent chromatin modification GO:0016569 254 0.464
chromosome segregation GO:0007059 114 0.462
cell cycle g2 m phase transition GO:0044839 43 0.459
regulation of meiotic cell cycle GO:0051445 4 0.438
organelle fission GO:0048285 149 0.406
regulation of mitotic sister chromatid separation GO:0010965 27 0.401
mitotic cell cycle process GO:1903047 286 0.399
histone modification GO:0016570 251 0.377
chromosome separation GO:0051304 23 0.363
multicellular organismal aging GO:0010259 3 0.358
microtubule based process GO:0007017 210 0.310
positive regulation of cell cycle GO:0045787 140 0.310
Rat
determination of adult lifespan GO:0008340 2 0.309
regulation of mitotic sister chromatid segregation GO:0033047 27 0.305
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.301
dna packaging GO:0006323 77 0.297
ribonucleoside monophosphate metabolic process GO:0009161 187 0.295
regulation of cell cycle process GO:0010564 266 0.294
Rat
regulation of gene silencing GO:0060968 24 0.294
microtubule cytoskeleton organization GO:0000226 176 0.288
positive regulation of developmental process GO:0051094 314 0.287
positive regulation of chromosome segregation GO:0051984 9 0.275
cellular response to dna damage stimulus GO:0006974 379 0.274
dna duplex unwinding GO:0032508 30 0.263
meiosis i GO:0007127 4 0.254
cell cycle dna replication GO:0044786 11 0.241
mitotic cell cycle checkpoint GO:0007093 68 0.226
regulation of cell diameter GO:0060305 1 0.211
positive regulation of meiotic cell cycle GO:0051446 2 0.207
chromatin modification GO:0016568 298 0.204
ribonucleoside catabolic process GO:0042454 406 0.199
nuclear dna replication GO:0033260 6 0.199
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.195
regulation of dna replication GO:0006275 68 0.183
double strand break repair via homologous recombination GO:0000724 50 0.175
positive regulation of cellular component organization GO:0051130 376 0.175
regulation of mitotic cell cycle GO:0007346 189 0.174
dna biosynthetic process GO:0071897 40 0.169
Fly
nuclear division GO:0000280 128 0.168
regulation of dna metabolic process GO:0051052 153 0.166
modification dependent macromolecule catabolic process GO:0043632 212 0.166
histone h3 k4 methylation GO:0051568 27 0.165
regulation of cell cycle phase transition GO:1901987 126 0.158
chromosome condensation GO:0030261 15 0.157
ribonucleoside monophosphate catabolic process GO:0009158 158 0.157
spindle organization GO:0007051 53 0.150
regulation of cytokinesis GO:0032465 45 0.148
cellular protein catabolic process GO:0044257 261 0.148
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.148
telomere maintenance GO:0000723 32 0.147
ubiquitin dependent protein catabolic process GO:0006511 206 0.142
meiotic chromosome segregation GO:0045132 4 0.139
positive regulation of cell cycle process GO:0090068 106 0.138
Rat
dna recombination GO:0006310 77 0.137
negative regulation of cell cycle process GO:0010948 121 0.131
oocyte maturation GO:0001556 1 0.129
cytokinesis GO:0000910 96 0.128
regulation of mitotic cell cycle phase transition GO:1901990 118 0.126
dna replication checkpoint GO:0000076 5 0.120
positive regulation of nuclear cell cycle dna replication GO:0010571 4 0.119
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.112
regulation of cell cycle GO:0051726 393 0.108
Rat
histone methylation GO:0016571 60 0.107
purine nucleotide catabolic process GO:0006195 405 0.105
cell cycle phase transition GO:0044770 173 0.098
mitotic chromosome condensation GO:0007076 11 0.098
dna integrity checkpoint GO:0031570 71 0.097
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.096
protein alkylation GO:0008213 74 0.096
exit from mitosis GO:0010458 10 0.094
g1 s transition of mitotic cell cycle GO:0000082 78 0.092
neurogenesis GO:0022008 169 0.090
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.086
response to biotic stimulus GO:0009607 276 0.086
Zebrafish
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.085
cell division GO:0051301 168 0.085
nervous system development GO:0007399 293 0.084
Fly
vesicle mediated transport GO:0016192 371 0.083
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.083
engulfment of apoptotic cell GO:0043652 2 0.083
immune response GO:0006955 307 0.083
cellular macromolecule catabolic process GO:0044265 380 0.082
embryo development GO:0009790 123 0.081
Zebrafish Worm
response to other organism GO:0051707 261 0.081
Zebrafish
triglyceride catabolic process GO:0019433 10 0.078
cell cycle checkpoint GO:0000075 117 0.077
dna geometric change GO:0032392 32 0.076
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.075
generation of neurons GO:0048699 152 0.072
ribonucleoside triphosphate metabolic process GO:0009199 412 0.071
regulation of protein kinase activity GO:0045859 289 0.070
humoral immune response GO:0006959 49 0.070
histone lysine methylation GO:0034968 50 0.070
purine ribonucleoside metabolic process GO:0046128 437 0.069
response to external biotic stimulus GO:0043207 261 0.069
Zebrafish
purine nucleoside triphosphate metabolic process GO:0009144 412 0.068
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.068
regulation of cell division GO:0051302 116 0.067
mitotic dna damage checkpoint GO:0044773 28 0.065
peripheral nervous system development GO:0007422 2 0.065
purine ribonucleotide catabolic process GO:0009154 404 0.065
regulation of dna dependent dna replication GO:0090329 19 0.065
regulation of proteasomal protein catabolic process GO:0061136 87 0.064
reciprocal meiotic recombination GO:0007131 4 0.062
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.062
atp catabolic process GO:0006200 157 0.062
proteasomal protein catabolic process GO:0010498 176 0.060
mitotic dna integrity checkpoint GO:0044774 30 0.060
growth GO:0040007 202 0.060
Zebrafish
regulation of chromosome organization GO:0033044 103 0.059
purine nucleoside monophosphate metabolic process GO:0009126 186 0.059
rna processing GO:0006396 255 0.058
cellular macromolecular complex assembly GO:0034622 324 0.058
regulation of purine nucleotide metabolic process GO:1900542 264 0.056
lagging strand elongation GO:0006273 3 0.055
purine nucleoside triphosphate catabolic process GO:0009146 392 0.055
nucleoside catabolic process GO:0009164 408 0.055
regulation of microtubule cytoskeleton organization GO:0070507 61 0.053
positive regulation of hydrolase activity GO:0051345 331 0.053
positive regulation of cell proliferation GO:0008284 301 0.053
Rat
protein methylation GO:0006479 74 0.052
positive regulation of catabolic process GO:0009896 310 0.050
rna dependent dna replication GO:0006278 16 0.048
cell cell signaling GO:0007267 155 0.048
positive regulation of cytokinesis GO:0032467 29 0.048
macromolecule methylation GO:0043414 97 0.046
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 2 0.046
nucleoside triphosphate catabolic process GO:0009143 394 0.046
dna repair GO:0006281 198 0.046
methylation GO:0032259 106 0.045
ribonucleoside triphosphate catabolic process GO:0009203 391 0.044
negative regulation of meiotic cell cycle GO:0051447 2 0.044
g2 m transition of mitotic cell cycle GO:0000086 41 0.044
mitotic sister chromatid cohesion GO:0007064 12 0.043
purine nucleoside catabolic process GO:0006152 398 0.043
response to fungus GO:0009620 4 0.042
Zebrafish
cellular response to lithium ion GO:0071285 2 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.041
protein homooligomerization GO:0051260 100 0.041
purine containing compound catabolic process GO:0072523 411 0.041
cell aging GO:0007569 52 0.041
7 methylguanosine mrna capping GO:0006370 7 0.041
regulation of cell cycle g1 s phase transition GO:1902806 42 0.041
cellular component assembly involved in morphogenesis GO:0010927 73 0.040
small gtpase mediated signal transduction GO:0007264 78 0.040
regulation of atp catabolic process GO:1903289 25 0.040
regulation of nuclear division GO:0051783 65 0.040
reproductive system development GO:0061458 56 0.039
Worm
neuron fate commitment GO:0048663 2 0.039
regeneration GO:0031099 4 0.039
dna strand elongation involved in dna replication GO:0006271 3 0.038
somatic stem cell maintenance GO:0035019 4 0.038
regulation of kinase activity GO:0043549 314 0.038
regulation of nucleotide metabolic process GO:0006140 269 0.038
negative regulation of dna metabolic process GO:0051053 57 0.037
regulation of protein catabolic process GO:0042176 155 0.037
organelle assembly GO:0070925 176 0.037
atp metabolic process GO:0046034 176 0.036
nucleotide catabolic process GO:0009166 408 0.036
membrane organization GO:0061024 292 0.036
negative regulation of apoptotic process GO:0043066 316 0.035
glycerolipid catabolic process GO:0046503 18 0.035
modification dependent protein catabolic process GO:0019941 209 0.035
protein modification by small protein conjugation GO:0032446 342 0.034
dna double strand break processing GO:0000729 10 0.033
reproductive structure development GO:0048608 55 0.033
Worm
positive regulation of cellular catabolic process GO:0031331 284 0.033
negative regulation of cell cycle phase transition GO:1901988 89 0.033
reciprocal dna recombination GO:0035825 4 0.033
cellular lipid catabolic process GO:0044242 65 0.033
regulation of microtubule polymerization GO:0031113 12 0.032
antimicrobial humoral response GO:0019730 26 0.032
negative regulation of cell size GO:0045792 3 0.032
reproductive process GO:0022414 106 0.031
Worm
sister chromatid cohesion GO:0007062 24 0.031
regulation of microtubule based process GO:0032886 74 0.030
regulation of cytoskeleton organization GO:0051493 177 0.029
reproduction GO:0000003 63 0.029
Worm
sex differentiation GO:0007548 45 0.029
Worm
muscle cell differentiation GO:0042692 63 0.029
developmental growth GO:0048589 48 0.028
Zebrafish
dna endoreduplication GO:0042023 5 0.028
actin cytoskeleton organization GO:0030036 207 0.028
nucleoside triphosphate metabolic process GO:0009141 422 0.028
organophosphate biosynthetic process GO:0090407 163 0.027
organophosphate catabolic process GO:0046434 430 0.027
negative regulation of mitosis GO:0045839 24 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
cell cycle g1 s phase transition GO:0044843 80 0.027
positive regulation of dna metabolic process GO:0051054 73 0.027
response to hypoxia GO:0001666 96 0.026
regulation of transferase activity GO:0051338 355 0.026
centrosome organization GO:0051297 58 0.026
regulation of atp metabolic process GO:1903578 29 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
oogenesis GO:0048477 2 0.025
negative regulation of mitotic cell cycle GO:0045930 102 0.025
female gamete generation GO:0007292 2 0.024
negative regulation of cell death GO:0060548 345 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
dna strand elongation GO:0022616 5 0.023
regulation of cellular ketone metabolic process GO:0010565 50 0.023
protein catabolic process GO:0030163 325 0.023
nucleosome assembly GO:0006334 50 0.023
cilium morphogenesis GO:0060271 75 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
compound eye development GO:0048749 1 0.023
negative regulation of catalytic activity GO:0043086 335 0.022
cilium organization GO:0044782 68 0.022
myosin filament organization GO:0031033 2 0.022
negative regulation of gene expression epigenetic GO:0045814 19 0.022
positive regulation of organelle organization GO:0010638 195 0.022
cell fate determination GO:0001709 3 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.021
actin filament based process GO:0030029 224 0.021
cation transport GO:0006812 331 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.020
cellular component morphogenesis GO:0032989 314 0.020
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.020
glycine metabolic process GO:0006544 4 0.020
gtp metabolic process GO:0046039 239 0.019
aging GO:0007568 66 0.019
dna catabolic process exonucleolytic GO:0000738 17 0.019
double strand break repair via nonhomologous end joining GO:0006303 10 0.019
oocyte development GO:0048599 1 0.019
cofactor biosynthetic process GO:0051188 31 0.019
leading strand elongation GO:0006272 1 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.019
dna catabolic process GO:0006308 49 0.019
nucleoside monophosphate metabolic process GO:0009123 191 0.018
regulation of growth GO:0040008 165 0.018
Zebrafish
positive regulation of fibroblast proliferation GO:0048146 21 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
centrosome duplication GO:0051298 28 0.018
cellular component disassembly GO:0022411 92 0.018
neuron development GO:0048666 113 0.018
negative regulation of protein modification process GO:0031400 200 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.017
positive regulation of mitosis GO:0045840 25 0.017
positive regulation of nuclear division GO:0051785 27 0.017
non recombinational repair GO:0000726 14 0.017
cellular ketone metabolic process GO:0042180 80 0.017
positive regulation of cell division GO:0051781 59 0.017
endocytosis GO:0006897 159 0.017
chromatin assembly or disassembly GO:0006333 78 0.016
cell growth GO:0016049 160 0.016
ras protein signal transduction GO:0007265 73 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
telomere organization GO:0032200 33 0.016
centrosome cycle GO:0007098 32 0.016
protein oligomerization GO:0051259 173 0.016
positive regulation of leukocyte activation GO:0002696 80 0.016
microtubule organizing center organization GO:0031023 62 0.016
embryo development ending in birth or egg hatching GO:0009792 34 0.016
Worm
regulation of triglyceride metabolic process GO:0090207 11 0.016
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.016
nucleosome organization GO:0034728 66 0.015
cell adhesion GO:0007155 325 0.015
regulation of proteolysis GO:0030162 293 0.015
negative regulation of transferase activity GO:0051348 124 0.015
mitotic g2 m transition checkpoint GO:0044818 9 0.015
negative regulation of chromosome organization GO:2001251 48 0.015
chemical homeostasis GO:0048878 306 0.015
regulation of binding GO:0051098 111 0.015
jak stat cascade GO:0007259 46 0.015
male meiosis GO:0007140 1 0.015
regulation of multicellular organism growth GO:0040014 8 0.015
Zebrafish
regulation of triglyceride catabolic process GO:0010896 6 0.015
positive regulation of cytoskeleton organization GO:0051495 83 0.015
regulation of t cell activation GO:0050863 77 0.015
neuroblast division GO:0055057 1 0.015
protein complex disassembly GO:0043241 52 0.014
negative regulation of chromatin silencing GO:0031936 4 0.014
positive regulation of chromosome organization GO:2001252 41 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
single organism reproductive process GO:0044702 98 0.014
Worm
development of primary sexual characteristics GO:0045137 35 0.014
Worm
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
dna damage checkpoint GO:0000077 68 0.014
regulation of exit from mitosis GO:0007096 6 0.014
positive regulation of growth GO:0045927 58 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
neuron differentiation GO:0030182 138 0.014
asymmetric stem cell division GO:0098722 1 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
response to abiotic stimulus GO:0009628 336 0.013
cellular amino acid metabolic process GO:0006520 116 0.013
asymmetric neuroblast division GO:0055059 1 0.013
sensory organ development GO:0007423 52 0.013
cell development GO:0048468 328 0.013
regulation of synaptic vesicle transport GO:1902803 3 0.013
autophagic cell death GO:0048102 3 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
purine nucleoside monophosphate catabolic process GO:0009128 158 0.013
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.013
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.012
cellular amine metabolic process GO:0044106 41 0.012
regulation of embryonic development GO:0045995 20 0.012
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 3 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.012
segmentation GO:0035282 4 0.012
positive regulation of proteolysis GO:0045862 142 0.012
cell type specific apoptotic process GO:0097285 125 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
dephosphorylation GO:0016311 209 0.012
gene silencing GO:0016458 49 0.012
oocyte differentiation GO:0009994 2 0.012
regulation of immune response GO:0050776 201 0.012
negative regulation of protein maturation GO:1903318 142 0.012
spermatogenesis GO:0007283 22 0.011
negative regulation of protein metabolic process GO:0051248 391 0.011
glial cell development GO:0021782 7 0.011
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
muscle cell development GO:0055001 29 0.011
eye development GO:0001654 42 0.011
cofactor metabolic process GO:0051186 87 0.011
centriole replication GO:0007099 13 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
endosome localization GO:0032439 2 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
regulation of chromosome segregation GO:0051983 44 0.011
neuronal stem cell division GO:0036445 1 0.011
response to inorganic substance GO:0010035 127 0.011
biological adhesion GO:0022610 331 0.011
regulation of ubiquitin protein transferase activity GO:0051438 28 0.011
response to decreased oxygen levels GO:0036293 96 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
positive regulation of t helper cell differentiation GO:0045624 2 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
cell projection organization GO:0030030 252 0.010
regulation of secretion GO:0051046 194 0.010
negative regulation of sister chromatid segregation GO:0033046 17 0.010

ORC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.017
inherited metabolic disorder DOID:655 242 0.017
disease of cellular proliferation DOID:14566 174 0.015
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.013