Homo sapiens

110 known processes

OTUB1

OTU domain, ubiquitin aldehyde binding 1

(Aliases: FLJ20113,MGC111158,OTB1,OTU1,FLJ40710,MGC4584)

OTUB1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ubiquitin dependent protein catabolic process GO:0006511 206 0.983
modification dependent protein catabolic process GO:0019941 209 0.982
protein ubiquitination GO:0016567 314 0.979
protein polyubiquitination GO:0000209 110 0.968
cellular protein catabolic process GO:0044257 261 0.951
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.947
protein modification by small protein conjugation GO:0032446 342 0.940
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.934
cellular macromolecule catabolic process GO:0044265 380 0.920
protein autoubiquitination GO:0051865 37 0.913
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.902
proteasomal protein catabolic process GO:0010498 176 0.899
negative regulation of cell death GO:0060548 345 0.881
modification dependent macromolecule catabolic process GO:0043632 212 0.832
regulation of proteolysis GO:0030162 293 0.793
negative regulation of apoptotic process GO:0043066 316 0.737
protein catabolic process GO:0030163 325 0.727
positive regulation of catabolic process GO:0009896 310 0.699
response to abiotic stimulus GO:0009628 336 0.691
regulation of proteasomal protein catabolic process GO:0061136 87 0.630
protein k48 linked ubiquitination GO:0070936 38 0.629
regulation of protein ubiquitination GO:0031396 95 0.622
regulation of cell cycle GO:0051726 393 0.608
purine nucleoside catabolic process GO:0006152 398 0.592
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.563
post embryonic development GO:0009791 2 0.554
glycosyl compound catabolic process GO:1901658 413 0.544
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.527
actin filament based process GO:0030029 224 0.503
regulation of cellular response to stress GO:0080135 244 0.481
mitotic cell cycle process GO:1903047 286 0.469
response to other organism GO:0051707 261 0.463
purine ribonucleotide catabolic process GO:0009154 404 0.454
organophosphate catabolic process GO:0046434 430 0.448
purine nucleotide catabolic process GO:0006195 405 0.444
small gtpase mediated signal transduction GO:0007264 78 0.435
chromatin modification GO:0016568 298 0.434
purine nucleoside triphosphate catabolic process GO:0009146 392 0.417
purine ribonucleoside metabolic process GO:0046128 437 0.405
covalent chromatin modification GO:0016569 254 0.400
positive regulation of cellular catabolic process GO:0031331 284 0.395
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.390
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.388
cell division GO:0051301 168 0.385
nucleoside catabolic process GO:0009164 408 0.383
rho protein signal transduction GO:0007266 26 0.378
positive regulation of proteolysis GO:0045862 142 0.377
protein k63 linked ubiquitination GO:0070534 31 0.373
wnt signaling pathway GO:0016055 156 0.373
secretion GO:0046903 254 0.373
nucleotide catabolic process GO:0009166 408 0.373
mitotic cell cycle phase transition GO:0044772 162 0.371
defense response GO:0006952 315 0.360
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.358
nucleoside triphosphate metabolic process GO:0009141 422 0.358
guanosine containing compound catabolic process GO:1901069 239 0.355
cell cycle phase transition GO:0044770 173 0.353
regulation of actin filament based process GO:0032970 141 0.353
negative regulation of programmed cell death GO:0043069 321 0.349
regulation of cytoskeleton organization GO:0051493 177 0.340
cellular response to dna damage stimulus GO:0006974 379 0.336
ribonucleoside triphosphate catabolic process GO:0009203 391 0.335
chromosome segregation GO:0007059 114 0.330
regulation of cell cycle process GO:0010564 266 0.321
negative regulation of cell cycle phase transition GO:1901988 89 0.320
protein maturation GO:0051604 233 0.318
mitotic cell cycle GO:0000278 326 0.317
regulation of protein catabolic process GO:0042176 155 0.315
guanosine containing compound metabolic process GO:1901068 244 0.308
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.301
negative regulation of cell cycle GO:0045786 193 0.294
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.290
protein processing GO:0016485 226 0.283
dna repair GO:0006281 198 0.282
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.280
chromatin organization GO:0006325 351 0.270
negative regulation of chromosome organization GO:2001251 48 0.267
ribonucleotide catabolic process GO:0009261 405 0.263
protein modification by small protein removal GO:0070646 92 0.262
autophagy GO:0006914 88 0.259
response to radiation GO:0009314 151 0.257
response to biotic stimulus GO:0009607 276 0.253
negative regulation of protein maturation GO:1903318 142 0.241
regulation of mitotic cell cycle GO:0007346 189 0.233
negative regulation of proteolysis GO:0045861 132 0.231
regulation of secretion by cell GO:1903530 177 0.229
ras protein signal transduction GO:0007265 73 0.228
protein deubiquitination GO:0016579 79 0.226
negative regulation of cell cycle process GO:0010948 121 0.223
histone modification GO:0016570 251 0.222
secretion by cell GO:0032940 226 0.221
cell cycle checkpoint GO:0000075 117 0.221
apoptotic signaling pathway GO:0097190 268 0.210
positive regulation of organelle organization GO:0010638 195 0.209
signal transduction in response to dna damage GO:0042770 57 0.209
positive regulation of protein ubiquitination GO:0031398 53 0.208
negative regulation of catalytic activity GO:0043086 335 0.206
nucleoside triphosphate catabolic process GO:0009143 394 0.205
cellular response to endogenous stimulus GO:0071495 336 0.205
response to external biotic stimulus GO:0043207 261 0.203
regulation of cellular protein catabolic process GO:1903362 96 0.201
mitotic cell cycle checkpoint GO:0007093 68 0.199
protein secretion GO:0009306 98 0.199
signal transduction by p53 class mediator GO:0072331 72 0.198
purine containing compound catabolic process GO:0072523 411 0.190
single organism membrane organization GO:0044802 268 0.189
positive regulation of hydrolase activity GO:0051345 331 0.187
gtp catabolic process GO:0006184 237 0.186
regulation of cellular component biogenesis GO:0044087 281 0.185
cellular response to abiotic stimulus GO:0071214 117 0.183
cell development GO:0048468 328 0.181
ribonucleoside catabolic process GO:0042454 406 0.180
endomembrane system organization GO:0010256 196 0.176
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.176
cation transport GO:0006812 331 0.175
positive regulation of cell death GO:0010942 263 0.174
cellular response to nutrient levels GO:0031669 69 0.173
response to organic cyclic compound GO:0014070 204 0.171
regulation of mitosis GO:0007088 63 0.168
mitotic sister chromatid segregation GO:0000070 53 0.167
regulation of response to external stimulus GO:0032101 222 0.164
purine ribonucleoside catabolic process GO:0046130 398 0.161
regulation of cell cycle phase transition GO:1901987 126 0.161
actin mediated cell contraction GO:0070252 12 0.158
cell morphogenesis GO:0000902 296 0.158
positive regulation of cellular protein catabolic process GO:1903364 37 0.155
microtubule based process GO:0007017 210 0.154
regulation of protein maturation GO:1903317 150 0.154
peptidyl lysine acetylation GO:0018394 101 0.149
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.146
positive regulation of programmed cell death GO:0043068 249 0.144
positive regulation of protein catabolic process GO:0045732 75 0.139
regulation of actin cytoskeleton organization GO:0032956 116 0.137
cellular response to organic cyclic compound GO:0071407 127 0.137
regulation of endopeptidase activity GO:0052548 170 0.134
regulation of chromosome organization GO:0033044 103 0.132
negative regulation of protein metabolic process GO:0051248 391 0.131
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.130
regulation of wnt signaling pathway GO:0030111 123 0.130
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.129
regulation of protein stability GO:0031647 87 0.127
cellular response to ionizing radiation GO:0071479 32 0.126
nucleoside phosphate catabolic process GO:1901292 412 0.122
negative regulation of protein processing GO:0010955 142 0.121
vesicle mediated transport GO:0016192 371 0.121
nucleoside monophosphate catabolic process GO:0009125 159 0.119
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.119
regulation of secretion GO:0051046 194 0.116
actin cytoskeleton organization GO:0030036 207 0.115
regulation of protein processing GO:0070613 150 0.115
negative regulation of protein modification process GO:0031400 200 0.107
negative regulation of multicellular organismal process GO:0051241 317 0.105
mitotic nuclear division GO:0007067 119 0.105
negative regulation of hydrolase activity GO:0051346 182 0.102
nervous system development GO:0007399 293 0.101
ion transmembrane transport GO:0034220 338 0.100
cellular component morphogenesis GO:0032989 314 0.100
cell projection organization GO:0030030 252 0.100
cytokine production GO:0001816 247 0.098
generation of neurons GO:0048699 152 0.098
oogenesis GO:0048477 2 0.097
regulation of gtp catabolic process GO:0033124 180 0.097
oocyte differentiation GO:0009994 2 0.094
enzyme linked receptor protein signaling pathway GO:0007167 303 0.093
cellular response to radiation GO:0071478 65 0.093
gtp metabolic process GO:0046039 239 0.092
regulation of response to dna damage stimulus GO:2001020 94 0.092
chromosome separation GO:0051304 23 0.089
intrinsic apoptotic signaling pathway GO:0097193 127 0.087
transmembrane transport GO:0055085 399 0.085
protein monoubiquitination GO:0006513 39 0.084
regulation of gtpase activity GO:0043087 180 0.083
regulation of protein localization GO:0032880 296 0.083
regulation of protein complex assembly GO:0043254 147 0.080
regulation of anatomical structure size GO:0090066 101 0.079
purine nucleoside triphosphate metabolic process GO:0009144 412 0.079
nitrogen compound transport GO:0071705 191 0.078
regulation of mitotic cell cycle phase transition GO:1901990 118 0.078
regulation of anatomical structure morphogenesis GO:0022603 286 0.078
negative regulation of organelle organization GO:0010639 126 0.077
neuromuscular junction development GO:0007528 3 0.076
mitochondrion organization GO:0007005 156 0.076
innate immune response GO:0045087 178 0.074
regulation of cell development GO:0060284 161 0.074
organelle fission GO:0048285 149 0.074
regulation of rho protein signal transduction GO:0035023 79 0.073
cytoplasmic transport GO:0016482 379 0.071
regulation of intracellular transport GO:0032386 195 0.070
mitotic dna integrity checkpoint GO:0044774 30 0.069
negative regulation of cellular protein metabolic process GO:0032269 353 0.069
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 10 0.068
single organism reproductive process GO:0044702 98 0.067
neuron projection development GO:0031175 106 0.066
response to oxygen containing compound GO:1901700 369 0.066
regulation of defense response GO:0031347 154 0.066
response to inorganic substance GO:0010035 127 0.066
vasculature development GO:0001944 181 0.065
positive regulation of cellular component organization GO:0051130 376 0.065
epithelial cell differentiation GO:0030855 141 0.065
neuron differentiation GO:0030182 138 0.065
positive regulation of cellular amine metabolic process GO:0033240 7 0.064
positive regulation of gtpase activity GO:0043547 166 0.064
regulation of cysteine type endopeptidase activity GO:2000116 127 0.063
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.061
microtubule cytoskeleton organization GO:0000226 176 0.061
establishment of protein localization to membrane GO:0090150 121 0.060
regulation of dna metabolic process GO:0051052 153 0.059
response to growth factor GO:0070848 205 0.058
negative regulation of cellular component organization GO:0051129 235 0.058
response to virus GO:0009615 126 0.058
positive regulation of secretion by cell GO:1903532 108 0.058
regulation of locomotion GO:0040012 329 0.058
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.058
positive regulation of phosphorylation GO:0042327 394 0.058
cellular homeostasis GO:0019725 196 0.058
mitotic sister chromatid separation GO:0051306 18 0.057
sister chromatid segregation GO:0000819 54 0.057
negative regulation of mitotic cell cycle GO:0045930 102 0.057
posttranscriptional regulation of gene expression GO:0010608 213 0.056
negative regulation of phosphorus metabolic process GO:0010563 267 0.055
regulation of cell morphogenesis GO:0022604 153 0.055
response to ionizing radiation GO:0010212 65 0.055
single organism cellular localization GO:1902580 332 0.054
regulation of chromosome segregation GO:0051983 44 0.054
positive regulation of secretion GO:0051047 116 0.054
regulation of purine nucleotide catabolic process GO:0033121 205 0.054
positive regulation of cytoskeleton organization GO:0051495 83 0.054
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.054
response to lipid GO:0033993 206 0.054
anatomical structure formation involved in morphogenesis GO:0048646 284 0.053
regulation of neurogenesis GO:0050767 82 0.053
cardiovascular system development GO:0072358 262 0.052
ribonucleoside triphosphate metabolic process GO:0009199 412 0.052
androgen receptor signaling pathway GO:0030521 34 0.052
cellular response to growth factor stimulus GO:0071363 197 0.051
regulation of cytokine production GO:0001817 232 0.051
regulation of apoptotic signaling pathway GO:2001233 175 0.051
actin filament based movement GO:0030048 17 0.051
immune effector process GO:0002252 159 0.051
positive regulation of transport GO:0051050 336 0.050
negative regulation of phosphorylation GO:0042326 174 0.050
internal peptidyl lysine acetylation GO:0018393 97 0.050
endocytosis GO:0006897 159 0.050
regulation of transmembrane transport GO:0034762 139 0.049
intracellular receptor signaling pathway GO:0030522 104 0.049
positive regulation of ras gtpase activity GO:0032320 117 0.049
negative regulation of cell proliferation GO:0008285 228 0.048
regulation of mitotic sister chromatid separation GO:0010965 27 0.048
ribosome biogenesis GO:0042254 48 0.048
response to bacterium GO:0009617 144 0.047
positive regulation of protein phosphorylation GO:0001934 313 0.047
nuclear division GO:0000280 128 0.046
regulation of cellular component movement GO:0051270 334 0.046
negative regulation of ion transport GO:0043271 39 0.046
positive regulation of chromatin modification GO:1903310 30 0.046
regulation of transferase activity GO:0051338 355 0.046
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.046
i kappab kinase nf kappab signaling GO:0007249 166 0.046
cytokinesis GO:0000910 96 0.046
immune response GO:0006955 307 0.045
regulation of ras protein signal transduction GO:0046578 155 0.044
female gamete generation GO:0007292 2 0.044
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.044
embryo development GO:0009790 123 0.044
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.043
cellular response to external stimulus GO:0071496 111 0.043
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.043
regulation of cellular ketone metabolic process GO:0010565 50 0.043
negative regulation of cytokine production GO:0001818 82 0.043
metal ion transport GO:0030001 272 0.042
protein acetylation GO:0006473 116 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.042
regulation of nucleoside metabolic process GO:0009118 209 0.041
negative regulation of apoptotic signaling pathway GO:2001234 97 0.041
negative regulation of protein catabolic process GO:0042177 59 0.040
cell cycle arrest GO:0007050 71 0.040
substantia nigra development GO:0021762 45 0.040
amine metabolic process GO:0009308 44 0.040
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.039
lens development in camera type eye GO:0002088 2 0.039
purine nucleoside monophosphate catabolic process GO:0009128 158 0.039
multicellular organism reproduction GO:0032504 42 0.039
response to nutrient levels GO:0031667 81 0.039
regulation of cell division GO:0051302 116 0.038
positive regulation of cell cycle GO:0045787 140 0.038
viral life cycle GO:0019058 132 0.038
regulation of ion transmembrane transport GO:0034765 132 0.038
multi organism reproductive process GO:0044703 54 0.037
protein acylation GO:0043543 138 0.037
cellular response to extracellular stimulus GO:0031668 72 0.037
regulation of transporter activity GO:0032409 82 0.037
membrane organization GO:0061024 292 0.037
cellular chemical homeostasis GO:0055082 180 0.037
regulation of nervous system development GO:0051960 88 0.036
cellular amine metabolic process GO:0044106 41 0.036
regulation of peptidase activity GO:0052547 180 0.036
actin filament organization GO:0007015 128 0.036
positive regulation of apoptotic process GO:0043065 246 0.035
regulation of ras gtpase activity GO:0032318 128 0.035
cellular response to lipid GO:0071396 127 0.035
negative regulation of phosphate metabolic process GO:0045936 267 0.035
regulation of cell differentiation GO:0045595 393 0.035
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.035
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.035
regulation of cellular component size GO:0032535 82 0.035
negative regulation of transport GO:0051051 176 0.035
cation transmembrane transport GO:0098655 238 0.035
regulation of innate immune response GO:0045088 97 0.035
negative regulation of intracellular signal transduction GO:1902532 183 0.034
positive regulation of developmental process GO:0051094 314 0.034
regulation of cell migration GO:0030334 289 0.034
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.034
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.034
regulation of small gtpase mediated signal transduction GO:0051056 156 0.033
maintenance of location GO:0051235 112 0.033
regulation of nucleotide catabolic process GO:0030811 205 0.033
cellular amino acid metabolic process GO:0006520 116 0.033
ion homeostasis GO:0050801 230 0.033
circulatory system development GO:0072359 262 0.033
cell morphogenesis involved in differentiation GO:0000904 144 0.033
regulation of cytoplasmic transport GO:1903649 149 0.033
dna damage checkpoint GO:0000077 68 0.033
double strand break repair GO:0006302 101 0.032
metaphase anaphase transition of cell cycle GO:0044784 21 0.032
midbrain development GO:0030901 45 0.032
steroid biosynthetic process GO:0006694 46 0.032
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.031
negative regulation of cellular catabolic process GO:0031330 83 0.031
regulation of calcium ion transport GO:0051924 79 0.031
regulation of chromatin organization GO:1902275 56 0.031
ribonucleoside monophosphate catabolic process GO:0009158 158 0.030
regulation of neuron projection development GO:0010975 57 0.030
inorganic cation transmembrane transport GO:0098662 194 0.030
ameboidal type cell migration GO:0001667 135 0.030
regulation of protein transport GO:0051223 213 0.030
regulation of vesicle mediated transport GO:0060627 130 0.029
regulation of growth GO:0040008 165 0.029
positive regulation of protein polymerization GO:0032273 45 0.029
negative regulation of defense response GO:0031348 47 0.029
histone acetylation GO:0016573 93 0.029
retrograde transport endosome to golgi GO:0042147 45 0.029
positive regulation of cell differentiation GO:0045597 211 0.029
cellular ketone metabolic process GO:0042180 80 0.028
regulation of cell projection organization GO:0031344 107 0.028
positive regulation of gtp catabolic process GO:0033126 166 0.028
regulation of neuron differentiation GO:0045664 70 0.028
internal protein amino acid acetylation GO:0006475 101 0.028
regulation of establishment of protein localization GO:0070201 242 0.028
oocyte development GO:0048599 1 0.028
cellular response to nitrogen compound GO:1901699 144 0.028
regulation of actin filament polymerization GO:0030833 50 0.027
lipid biosynthetic process GO:0008610 177 0.027
dna integrity checkpoint GO:0031570 71 0.027
regulation of actin polymerization or depolymerization GO:0008064 56 0.027
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.027
mitotic dna damage checkpoint GO:0044773 28 0.027
cellular response to oxygen containing compound GO:1901701 276 0.026
cell part morphogenesis GO:0032990 137 0.026
trabecula morphogenesis GO:0061383 2 0.026
protein targeting GO:0006605 187 0.025
negative regulation of response to external stimulus GO:0032102 83 0.025
developmental process involved in reproduction GO:0003006 66 0.025
regulation of protein secretion GO:0050708 86 0.025
regulation of chromatin modification GO:1903308 51 0.025
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.025
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.025
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.024
positive regulation of protein complex assembly GO:0031334 86 0.024
regulation of ion transport GO:0043269 189 0.024
reactive oxygen species metabolic process GO:0072593 75 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
regulation of metal ion transport GO:0010959 120 0.023
protein k48 linked deubiquitination GO:0071108 19 0.023
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.023
multicellular organismal aging GO:0010259 3 0.023
protein localization to organelle GO:0033365 280 0.023
biological adhesion GO:0022610 331 0.022
growth GO:0040007 202 0.022
neuron development GO:0048666 113 0.022
response to starvation GO:0042594 59 0.022
regulation of notch signaling pathway GO:0008593 18 0.021
calcium ion transport GO:0006816 147 0.021
response to extracellular stimulus GO:0009991 85 0.021
regulation of homeostatic process GO:0032844 121 0.021
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
positive regulation of mapk cascade GO:0043410 190 0.020
negative regulation of phosphatase activity GO:0010923 61 0.020
interspecies interaction between organisms GO:0044419 156 0.020
mitotic cytokinesis GO:0000281 19 0.020
immune system development GO:0002520 195 0.020
organelle localization GO:0051640 84 0.020
neural tube formation GO:0001841 3 0.020
organelle fusion GO:0048284 36 0.020
establishment of protein localization to plasma membrane GO:0090002 68 0.019
calcium ion transmembrane transport GO:0070588 76 0.019
endosomal transport GO:0016197 129 0.019
regulation of ion transmembrane transporter activity GO:0032412 72 0.019
signal release GO:0023061 70 0.019
viral process GO:0016032 146 0.019
canonical wnt signaling pathway GO:0060070 116 0.019
mitotic cytokinetic process GO:1902410 2 0.019
multi organism cellular process GO:0044764 156 0.019
defense response to other organism GO:0098542 129 0.019
cell projection morphogenesis GO:0048858 129 0.018
response to metal ion GO:0010038 84 0.018
protein polymerization GO:0051258 71 0.018
regulation of ubiquitin protein transferase activity GO:0051438 28 0.018
protein stabilization GO:0050821 64 0.018
regulation of sister chromatid segregation GO:0033045 27 0.018
regulation of ion homeostasis GO:2000021 73 0.018
receptor mediated endocytosis GO:0006898 84 0.018
regulation of transmembrane transporter activity GO:0022898 74 0.018
g1 dna damage checkpoint GO:0044783 18 0.017
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.017
positive regulation of response to dna damage stimulus GO:2001022 43 0.017
regulation of cellular response to growth factor stimulus GO:0090287 76 0.017
stem cell development GO:0048864 69 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
protein oligomerization GO:0051259 173 0.017
regulation of cell motility GO:2000145 299 0.017
cellular response to organonitrogen compound GO:0071417 124 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.017
cellular response to starvation GO:0009267 58 0.017
negative regulation of sister chromatid segregation GO:0033046 17 0.017
meiotic chromosome segregation GO:0045132 4 0.017
reproductive system development GO:0061458 56 0.017
negative regulation of immune system process GO:0002683 136 0.017
negative regulation of cellular protein catabolic process GO:1903363 38 0.017
positive regulation of endopeptidase activity GO:0010950 84 0.017
protein localization to plasma membrane GO:0072659 93 0.017
dna replication GO:0006260 116 0.017
positive regulation of protein transport GO:0051222 135 0.016
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.016
positive regulation of endocytosis GO:0045807 42 0.016
establishment of tissue polarity GO:0007164 3 0.016
negative regulation of secretion GO:0051048 58 0.016
dna recombination GO:0006310 77 0.016
mitochondrial transport GO:0006839 60 0.016
negative regulation of transmembrane transport GO:0034763 29 0.016
interleukin 8 production GO:0032637 51 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
protein k29 linked ubiquitination GO:0035519 4 0.016
chemical homeostasis GO:0048878 306 0.016
neuron projection morphogenesis GO:0048812 50 0.016
negative regulation of secretion by cell GO:1903531 52 0.016
hormone transport GO:0009914 68 0.016
homotypic cell cell adhesion GO:0034109 47 0.016
nuclear transport GO:0051169 179 0.015
regulation of microtubule based process GO:0032886 74 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
leukocyte migration GO:0050900 107 0.015
oxidoreduction coenzyme metabolic process GO:0006733 19 0.015
positive regulation of dendrite morphogenesis GO:0050775 3 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.015
mapk cascade GO:0000165 288 0.015
regulation of cell activation GO:0050865 125 0.015
negative regulation of dna metabolic process GO:0051053 57 0.015
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.015
dna damage response signal transduction resulting in transcription GO:0042772 12 0.015
positive regulation of actin filament polymerization GO:0030838 38 0.015
response to lipopolysaccharide GO:0032496 70 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
regulation of autophagy GO:0010506 52 0.015
protein localization to membrane GO:0072657 160 0.015
divalent metal ion transport GO:0070838 152 0.015
organelle inheritance GO:0048308 2 0.015
cation homeostasis GO:0055080 189 0.015
protein deacylation GO:0035601 39 0.014
lipid metabolic process GO:0006629 381 0.014
cerebral cortex cell migration GO:0021795 3 0.014
regulation of nuclear division GO:0051783 65 0.014
angiogenesis GO:0001525 147 0.014
cellular protein complex assembly GO:0043623 188 0.014
reproductive process GO:0022414 106 0.014
positive regulation of immune response GO:0050778 159 0.014
negative regulation of ion transmembrane transport GO:0034766 26 0.014
response to cytokine GO:0034097 232 0.014
system process GO:0003008 349 0.014
protein autophosphorylation GO:0046777 123 0.014
positive regulation of transferase activity GO:0051347 227 0.014
gene silencing GO:0016458 49 0.014

OTUB1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.042
retinal disease DOID:5679 118 0.014
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
nervous system disease DOID:863 431 0.014
eye disease DOID:5614 149 0.014
cancer DOID:162 167 0.014
organ system cancer DOID:0050686 164 0.014