|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.996
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.994
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.985
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.982
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.981
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.978
|
Human |
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.978
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.977
|
Human |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.968
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.967
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.961
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.957
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.948
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.947
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.947
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.947
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.946
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.939
|
Human |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.937
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.933
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.923
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.923
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.922
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.922
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.921
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.921
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.913
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.913
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.911
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.906
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.904
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.888
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.884
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.882
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.879
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.875
|
|
|
|
regulation of lamellipodium morphogenesis
|
GO:2000392 |
4 |
0.872
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
1 |
0.869
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.856
|
Human |
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.854
|
Human |
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.843
|
Yeast |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.838
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.837
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.826
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.812
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.804
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.804
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.802
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.796
|
Human |
|
|
negative regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis
|
GO:2001271 |
3 |
0.783
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.778
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.776
|
Human |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.774
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.774
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.756
|
Human |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.752
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.751
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.737
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.735
|
|
|
|
contact inhibition
|
GO:0060242 |
3 |
0.733
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.728
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.722
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.715
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.706
|
Worm |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.706
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.703
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.681
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.680
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.674
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.670
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.670
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.666
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.664
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.664
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.658
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.655
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.652
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.652
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.648
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.645
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.637
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.636
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.631
|
Worm |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.631
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.629
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.623
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.609
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.609
|
Human |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.606
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.604
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.601
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.601
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.592
|
Worm |
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.589
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.588
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.586
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.586
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.583
|
Human Yeast |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.577
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.575
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.574
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.570
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.567
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.566
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.560
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.555
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.554
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.554
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.553
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.553
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.549
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.545
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.535
|
Human Yeast |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.531
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.530
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.523
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.500
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.498
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.495
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.495
|
|
|
|
growth
|
GO:0040007 |
202 |
0.493
|
Yeast |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.488
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.487
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.487
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.482
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.476
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.466
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.464
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.460
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.460
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.453
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.449
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.447
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.445
|
Worm |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.445
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.439
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.437
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.433
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.430
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.428
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.424
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.422
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.420
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.412
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.410
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.404
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.397
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.397
|
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.393
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.392
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.388
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.386
|
Human |
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.385
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.381
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.374
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.373
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.372
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.371
|
Worm |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.365
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.360
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.357
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.355
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.354
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.354
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.351
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.346
|
Human |
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.344
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.342
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.340
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.339
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.333
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.328
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.321
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.320
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.318
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.317
|
Yeast Worm |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.315
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.312
|
Human |
|
|
positive regulation of lamellipodium morphogenesis
|
GO:2000394 |
2 |
0.311
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.310
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.305
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.300
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.291
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.288
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.287
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.284
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.281
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.280
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.277
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.273
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.261
|
Human Yeast |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.258
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.256
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.254
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.253
|
Human Yeast |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.251
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.250
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.248
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.246
|
|
|
|
regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis
|
GO:2001270 |
3 |
0.244
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.242
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.240
|
Yeast |
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.232
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.231
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.222
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.221
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.221
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.220
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.219
|
Worm |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.219
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.213
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.212
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.211
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.209
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.209
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.209
|
Worm |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.206
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.201
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.201
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.198
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.194
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.194
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.194
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.194
|
Human |
|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
0.193
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.192
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.190
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.190
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.189
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.188
|
Human |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.187
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.185
|
Yeast |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.184
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.181
|
Yeast |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.181
|
Human |
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.180
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.177
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.175
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.175
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.175
|
Human Yeast |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.173
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.169
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.169
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.166
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.165
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.163
|
|
|
|
fibroblast migration
|
GO:0010761 |
7 |
0.158
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.158
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
12 |
0.158
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.153
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.153
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.152
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.152
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
6 |
0.151
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.148
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.147
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.147
|
Yeast |
|
|
neuron development
|
GO:0048666 |
113 |
0.146
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.144
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.144
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.143
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.143
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.142
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.141
|
Worm |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.141
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.140
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.139
|
Yeast |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.139
|
Human |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.138
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.137
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.136
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.136
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.135
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.135
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.133
|
Yeast |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.132
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.132
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.130
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.128
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.127
|
Yeast |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.127
|
Human |
|
|
cell competition in a multicellular organism
|
GO:0035212 |
1 |
0.124
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.123
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.120
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.119
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.119
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.118
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.117
|
Human Yeast |
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.117
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.116
|
Yeast |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.115
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.115
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.114
|
|
|
|
positive regulation of t cell chemotaxis
|
GO:0010820 |
7 |
0.114
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.114
|
Yeast |
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.113
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.112
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.111
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.111
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.110
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.110
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.108
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.108
|
Yeast |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.108
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.108
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.107
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.107
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.105
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.103
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.103
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.102
|
Human |
|
|
olfactory bulb development
|
GO:0021772 |
5 |
0.101
|
|
|
|
tangential migration from the subventricular zone to the olfactory bulb
|
GO:0022028 |
3 |
0.101
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.100
|
Yeast |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.099
|
Yeast |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.099
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.098
|
|
|
|
system process
|
GO:0003008 |
349 |
0.098
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.096
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.096
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.095
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.093
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.092
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.092
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.091
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.090
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.089
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.089
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.089
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.088
|
Yeast |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.088
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.087
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.087
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.086
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.085
|
Yeast |
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.084
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.084
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.081
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.081
|
Yeast |
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.080
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.079
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.078
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.078
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.077
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.076
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.075
|
Yeast |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.075
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.075
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.074
|
Yeast |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.074
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.073
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.073
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.072
|
Yeast |
|
|
reproduction
|
GO:0000003 |
63 |
0.072
|
Yeast |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.071
|
Yeast |
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.070
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.070
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.069
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.068
|
Yeast |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.068
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.068
|
Yeast |
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.068
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.067
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.067
|
Human |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.066
|
Human |
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.065
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.065
|
|
|
|
forebrain neuron development
|
GO:0021884 |
2 |
0.065
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.064
|
|
|
|
sterol transmembrane transport
|
GO:0035382 |
4 |
0.064
|
Yeast |
|
|
activation of ras gtpase activity
|
GO:0032856 |
15 |
0.064
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.063
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.063
|
Human |
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.061
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.061
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.060
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.060
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.058
|
Yeast |
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.057
|
Yeast |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.057
|
|
|
|
regulation of intracellular estrogen receptor signaling pathway
|
GO:0033146 |
13 |
0.057
|
Human |
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.057
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.057
|
|
|
|
memory
|
GO:0007613 |
3 |
0.056
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.056
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.056
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.056
|
|
|
|
regulation of synaptic vesicle endocytosis
|
GO:1900242 |
1 |
0.056
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.055
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.055
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.054
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.054
|
|
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
22 |
0.054
|
Human |
|
|
head development
|
GO:0060322 |
108 |
0.054
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.053
|
Yeast |
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.053
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.053
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.053
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.053
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.052
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.051
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.051
|
Yeast |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.051
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.051
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.051
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.051
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.050
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.049
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.049
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.049
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.049
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.049
|
Yeast |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.048
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.047
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.047
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.047
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.047
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.046
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.046
|
Yeast |
|
|
response to insulin
|
GO:0032868 |
45 |
0.045
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.045
|
Human Yeast |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.045
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.045
|
Yeast |
|
|
sensory perception
|
GO:0007600 |
103 |
0.044
|
|
|
|
synapse organization
|
GO:0050808 |
14 |
0.043
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.043
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.043
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.042
|
|
|
|
positive regulation of lamellipodium organization
|
GO:1902745 |
12 |
0.042
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.041
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.041
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.041
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.041
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.040
|
Yeast |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.040
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.040
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.039
|
Human |
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.039
|
|
|
|
axis specification
|
GO:0009798 |
12 |
0.039
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.039
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.038
|
Yeast |
|
|
cell growth
|
GO:0016049 |
160 |
0.038
|
Yeast |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.038
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.038
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.038
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.037
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.037
|
Yeast |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.037
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.037
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.037
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.036
|
Yeast |
|
|
negative regulation of lamellipodium assembly
|
GO:0010593 |
2 |
0.036
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.035
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.035
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.035
|
Human |
|
|
regulation of cell cell adhesion mediated by cadherin
|
GO:2000047 |
4 |
0.035
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.035
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.035
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.035
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.034
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.034
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.034
|
Yeast |
|
|
rna localization
|
GO:0006403 |
41 |
0.034
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.034
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.034
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.033
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.033
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.033
|
|
|
|
positive regulation of arp2 3 complex mediated actin nucleation
|
GO:2000601 |
5 |
0.033
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.032
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.032
|
|
|
|
regulation of synapse structural plasticity
|
GO:0051823 |
2 |
0.031
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.031
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.031
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.031
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.031
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.031
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.031
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
4 |
0.030
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.030
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.030
|
Yeast |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.030
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.030
|
Yeast |
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.029
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.029
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.029
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.029
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.029
|
Yeast |
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.029
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.029
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.029
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.029
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
28 |
0.028
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.028
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.028
|
|
