|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.425
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.331
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.309
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.297
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.296
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.274
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.274
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.269
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.265
|
|
|
|
memory
|
GO:0007613 |
3 |
0.256
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.255
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.253
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.252
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.251
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.235
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.234
|
|
|
|
system process
|
GO:0003008 |
349 |
0.233
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.230
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.227
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.217
|
Human Rat |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.215
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.213
|
Mouse Rat |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.212
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.210
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.209
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.207
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.200
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.196
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.193
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.193
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.191
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.186
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.185
|
Mouse Rat |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.184
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.182
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.179
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.176
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.174
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.172
|
Mouse Rat |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.169
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.167
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.165
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.163
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.162
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.160
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.159
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.154
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.154
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.154
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.154
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.152
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.151
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.145
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.143
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.143
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.141
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.141
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.140
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.138
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.138
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.137
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.137
|
Yeast |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.135
|
Human |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.134
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.132
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.131
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.130
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.128
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.127
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.125
|
Mouse Rat |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.124
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.123
|
Mouse Rat |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.122
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.119
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.119
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.118
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.117
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.115
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.114
|
Rat |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.110
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.110
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.110
|
Human Yeast |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.110
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.109
|
|
|
|
cell cell adhesion mediated by cadherin
|
GO:0044331 |
4 |
0.108
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.107
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.106
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.106
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.105
|
Mouse Rat |
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.104
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.100
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.097
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.094
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.093
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.093
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.092
|
Rat |
|
|
neuron development
|
GO:0048666 |
113 |
0.091
|
Mouse Rat |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.091
|
Mouse Rat |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.090
|
|
|
|
regulation of transmission of nerve impulse
|
GO:0051969 |
2 |
0.089
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.085
|
|
|
|
establishment of neuroblast polarity
|
GO:0045200 |
1 |
0.085
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.082
|
Rat |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.082
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.082
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.082
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.082
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.082
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.081
|
Mouse Rat |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.081
|
Human Yeast |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.080
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.079
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.078
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.076
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.074
|
Yeast |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.074
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.072
|
Mouse Rat |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.071
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.071
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.070
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.068
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.066
|
|
|
|
regulation of cell cell adhesion mediated by cadherin
|
GO:2000047 |
4 |
0.066
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.065
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.065
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.064
|
|
|
|
growth
|
GO:0040007 |
202 |
0.064
|
Yeast |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.064
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.063
|
Worm |
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.063
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.062
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.062
|
Human |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.061
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.060
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.059
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.059
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.057
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.057
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.056
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.056
|
Human |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.055
|
Rat |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.054
|
Yeast |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.053
|
Yeast |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.053
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.053
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.053
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.052
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.052
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.052
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.052
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.051
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.051
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.051
|
|
|
|
establishment or maintenance of neuroblast polarity
|
GO:0045196 |
1 |
0.050
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.050
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.050
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.050
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.050
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.050
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.050
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.050
|
Rat |
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.049
|
Human |
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.049
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.049
|
Human |
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.048
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.048
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.047
|
Mouse Rat |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.047
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.047
|
Yeast |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.047
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.047
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.046
|
Human |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.046
|
Mouse Rat |
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.045
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.044
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.043
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.043
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.043
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.043
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.042
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.042
|
Human |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.041
|
Rat |
|
|
secretion
|
GO:0046903 |
254 |
0.041
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.041
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.040
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.040
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.040
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.040
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.039
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.039
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.039
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.038
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.038
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.038
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.038
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.038
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.038
|
Rat |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.037
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.037
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.037
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.037
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.037
|
Human |
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.036
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.036
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.036
|
Mouse Rat |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.036
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.036
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.035
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.035
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.035
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.035
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.035
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.035
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.035
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.034
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.034
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.034
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.034
|
Yeast |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.033
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.033
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.033
|
|
|
|
mating
|
GO:0007618 |
1 |
0.033
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.032
|
Rat |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.032
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.032
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.032
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.032
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.031
|
Human |
|
|
cell growth
|
GO:0016049 |
160 |
0.031
|
Yeast |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.031
|
Yeast |
|
|
negative regulation of transmission of nerve impulse
|
GO:0051970 |
1 |
0.031
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.030
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.030
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.030
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.029
|
Rat |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.029
|
Yeast |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.029
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
4 |
0.029
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.029
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.029
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.028
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.028
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.028
|
Yeast |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.028
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.028
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.028
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.028
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.028
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.028
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.028
|
Yeast |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.027
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.027
|
Mouse Rat |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.026
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.026
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.026
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.026
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.026
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.026
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.026
|
Yeast |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.026
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.026
|
Human |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.026
|
|
|
|
brain derived neurotrophic factor receptor signaling pathway
|
GO:0031547 |
1 |
0.026
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.026
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.025
|
|
|
|
head development
|
GO:0060322 |
108 |
0.025
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.025
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.025
|
|
|
|
cloaca development
|
GO:0035844 |
1 |
0.025
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.025
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.025
|
Yeast |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.025
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.025
|
|
|
|
cellular response to histamine
|
GO:0071420 |
3 |
0.025
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.025
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.025
|
|
|
|
adenylate cyclase inhibiting adrenergic receptor signaling pathway
|
GO:0071881 |
1 |
0.024
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.024
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.024
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.024
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.024
|
|
|
|
regulation of atrial cardiac muscle cell membrane repolarization
|
GO:0060372 |
4 |
0.024
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.024
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.024
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.024
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.023
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.023
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.023
|
Yeast |
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.023
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.023
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.023
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.023
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.023
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.023
|
Rat |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.023
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.023
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.023
|
|
|
|
regulation of acrosome reaction
|
GO:0060046 |
4 |
0.023
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.023
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.023
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.023
|
Yeast |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.023
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.023
|
|
|
|
gamma aminobutyric acid signaling pathway
|
GO:0007214 |
3 |
0.022
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.022
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.022
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.022
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.022
|
Rat |
|
|
response to wounding
|
GO:0009611 |
168 |
0.022
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.022
|
|
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.022
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.022
|
Human Yeast Rat |
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.022
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.021
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.021
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.021
|
Rat |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.021
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.021
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.021
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.021
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.020
|
Rat |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.020
|
Yeast |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.020
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.020
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.020
|
Worm |
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.020
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.020
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.020
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.020
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.020
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.020
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.020
|
|
|
|
positive regulation of synapse structural plasticity
|
GO:0051835 |
2 |
0.019
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.019
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.019
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.019
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.019
|
Human |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.019
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.019
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.019
|
Human |
|
|
regulation of synapse structural plasticity
|
GO:0051823 |
2 |
0.019
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.019
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.019
|
Yeast |
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.019
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.019
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.019
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.018
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.018
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.018
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.018
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.018
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.018
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.018
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.018
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.018
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.017
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.017
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.017
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.017
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.017
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.017
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.017
|
Yeast |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.017
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.017
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.017
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.017
|
Yeast |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.017
|
Worm |
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.017
|
|
|
|
av node cell to bundle of his cell communication
|
GO:0086067 |
4 |
0.017
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.017
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.017
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.017
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.017
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.016
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.016
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.016
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.016
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.016
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.016
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.016
|
Yeast |
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.016
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.016
|
Rat |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.016
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
1 |
0.016
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.016
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.016
|
Human Yeast Rat |
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.016
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.016
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.016
|
Yeast |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.016
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.016
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.016
|
Rat |
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.016
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.016
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.015
|
Human |
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.015
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.015
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.015
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
1 |
0.015
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.015
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.015
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.015
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.015
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.015
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.015
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.015
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.015
|
Human |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.015
|
Human |
|
|
cgmp catabolic process
|
GO:0046069 |
3 |
0.015
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.015
|
Yeast |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.015
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.015
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.015
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.015
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.015
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.015
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.015
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.015
|
Rat |
|
|
protein processing
|
GO:0016485 |
226 |
0.015
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.015
|
Human |
|
|
response to activity
|
GO:0014823 |
0 |
0.015
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.014
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.014
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.014
|
Yeast |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.014
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.014
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.014
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.014
|
Human |
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.014
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.014
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.014
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.014
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.014
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.014
|
Yeast Worm |
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.014
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.014
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.014
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.014
|
Yeast |
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.014
|
Rat |
|
|
segmentation
|
GO:0035282 |
4 |
0.014
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.014
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.014
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.013
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.013
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.013
|
Rat |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.013
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.013
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.013
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.013
|
Yeast |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.013
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.013
|
Yeast |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.013
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.013
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.013
|
Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.013
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.013
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.013
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.013
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.013
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.013
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.013
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.013
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.013
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.013
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.013
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.013
|
Rat |
|
|
protein targeting
|
GO:0006605 |
187 |
0.013
|
Yeast |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.013
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.013
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.013
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.013
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.013
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.013
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.013
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.013
|
|
|
|
regulation of collateral sprouting
|
GO:0048670 |
2 |
0.013
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.013
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.013
|
Human Yeast Rat |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.012
|
Human |
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.012
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.012
|
Human |
|
|
developmental growth
|
GO:0048589 |
48 |
0.012
|
|
