Homo sapiens

44 known processes

PARP9

poly (ADP-ribose) polymerase family, member 9

(Aliases: DKFZp686M15238,MGC:7868,FLJ43593,FLJ35310,FLJ41418,BAL,FLJ26637,BAL1,DKFZp666B0810)

PARP9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 35 0.931
Human
response to cytokine GO:0034097 232 0.918
macromolecule glycosylation GO:0043413 63 0.874
Human
protein glycosylation GO:0006486 62 0.857
Human
negative regulation of protein import into nucleus translocation GO:0033159 3 0.839
Human
regulation of viral genome replication GO:0045069 48 0.810
Human
interspecies interaction between organisms GO:0044419 156 0.803
Human
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.774
Human
protein modification by small protein conjugation GO:0032446 342 0.771
Human
chromatin assembly or disassembly GO:0006333 78 0.767
Human
protein polyubiquitination GO:0000209 110 0.732
Human
glycosylation GO:0070085 71 0.710
Human
chromatin organization GO:0006325 351 0.689
Human
defense response to virus GO:0051607 71 0.689
glycoprotein biosynthetic process GO:0009101 91 0.684
Human
chromatin assembly GO:0031497 61 0.641
Human
regulation of protein import into nucleus GO:0042306 78 0.627
Human
single organism carbohydrate metabolic process GO:0044723 193 0.598
Human
protein ubiquitination GO:0016567 314 0.597
Human
dna repair GO:0006281 198 0.565
double strand break repair GO:0006302 101 0.515
glycoprotein metabolic process GO:0009100 110 0.498
Human
protein import into nucleus GO:0006606 104 0.443
Human
fibroblast proliferation GO:0048144 33 0.436
Human
positive regulation of rig i signaling pathway GO:1900246 4 0.423
intracellular protein transport GO:0006886 270 0.413
Human
multi organism cellular process GO:0044764 156 0.408
Human
response to biotic stimulus GO:0009607 276 0.399
nuclear transport GO:0051169 179 0.398
Human
protein targeting GO:0006605 187 0.379
Human
viral process GO:0016032 146 0.373
Human
histone ubiquitination GO:0016574 31 0.358
response to other organism GO:0051707 261 0.354
innate immune response GO:0045087 178 0.343
protein import GO:0017038 130 0.342
Human
carbohydrate metabolic process GO:0005975 207 0.341
Human
negative regulation of protein polyubiquitination GO:1902915 4 0.331
Human
defense response GO:0006952 315 0.328
negative regulation of protein k63 linked ubiquitination GO:1900045 4 0.309
Human
single organism cellular localization GO:1902580 332 0.287
Human
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.270
notch receptor processing GO:0007220 2 0.259
vesicle mediated transport GO:0016192 371 0.231
viral genome replication GO:0019079 50 0.231
Human
regulation of intracellular transport GO:0032386 195 0.224
Human
establishment of protein localization to organelle GO:0072594 172 0.221
Human
negative regulation of transport GO:0051051 176 0.219
Human
response to external biotic stimulus GO:0043207 261 0.215
protein auto adp ribosylation GO:0070213 4 0.214
Human
regulation of protein polyubiquitination GO:1902914 8 0.210
Human
positive regulation of multi organism process GO:0043902 56 0.210
mda 5 signaling pathway GO:0039530 4 0.206
histone monoubiquitination GO:0010390 20 0.204
nucleocytoplasmic transport GO:0006913 176 0.195
Human
regulation of protein localization GO:0032880 296 0.194
Human
negative regulation of multicellular organismal process GO:0051241 317 0.192
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.191
Human
regulation of defense response to virus GO:0050688 33 0.180
regulation of protein ubiquitination GO:0031396 95 0.178
Human
regulation of chromatin assembly or disassembly GO:0001672 6 0.169
Human
regulation of defense response GO:0031347 154 0.156
regulation of cellular component biogenesis GO:0044087 281 0.153
Human
immune effector process GO:0002252 159 0.151
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.151
Human
positive regulation of interferon alpha production GO:0032727 11 0.151
regulation of cytoplasmic transport GO:1903649 149 0.148
Human
response to organic cyclic compound GO:0014070 204 0.140
intracellular receptor signaling pathway GO:0030522 104 0.139
regulation of cell differentiation GO:0045595 393 0.138
regulation of dna metabolic process GO:0051052 153 0.138
Human
rna interference GO:0016246 4 0.135
covalent chromatin modification GO:0016569 254 0.129
protein catabolic process GO:0030163 325 0.127
regulation of protein targeting GO:1903533 91 0.120
Human
regulation of mda 5 signaling pathway GO:0039533 4 0.116
regulation of viral process GO:0050792 103 0.115
Human
positive regulation of immune system process GO:0002684 283 0.113
positive regulation of catabolic process GO:0009896 310 0.113
positive regulation of interferon beta production GO:0032728 17 0.113
negative regulation of cellular protein metabolic process GO:0032269 353 0.107
Human
negative regulation of protein ubiquitination GO:0031397 35 0.103
Human
negative regulation of protein modification process GO:0031400 200 0.099
Human
regulation of intracellular protein transport GO:0033157 123 0.098
Human
cellular response to dna damage stimulus GO:0006974 379 0.098
regulation of cell development GO:0060284 161 0.092
gene silencing by mirna GO:0035195 23 0.091
regulation of immune effector process GO:0002697 91 0.090
purine containing compound biosynthetic process GO:0072522 88 0.089
rig i signaling pathway GO:0039529 7 0.088
immune response GO:0006955 307 0.084
nucleoside phosphate biosynthetic process GO:1901293 109 0.082
regulation of fibroblast proliferation GO:0048145 32 0.078
Human
regulation of multi organism process GO:0043900 157 0.078
Human
protein adp ribosylation GO:0006471 9 0.078
Human
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.077
Human
chemical homeostasis GO:0048878 306 0.072
viral life cycle GO:0019058 132 0.071
Human
nervous system development GO:0007399 293 0.071
cellular response to nitrogen compound GO:1901699 144 0.070
positive regulation of protein catabolic process GO:0045732 75 0.069
response to nitrogen compound GO:1901698 184 0.067
negative regulation of multi organism process GO:0043901 92 0.066
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.066
Human
negative regulation of defense response to virus GO:0050687 10 0.064
rna processing GO:0006396 255 0.064
wnt signaling pathway GO:0016055 156 0.063
regulation of response to biotic stimulus GO:0002831 55 0.059
organophosphate biosynthetic process GO:0090407 163 0.057
atp metabolic process GO:0046034 176 0.057
regulation of chromosome organization GO:0033044 103 0.056
Human
response to dsrna GO:0043331 25 0.056
regulation of establishment of protein localization GO:0070201 242 0.056
Human
regulation of protein import into nucleus translocation GO:0033158 10 0.055
Human
cytoplasmic transport GO:0016482 379 0.055
Human
regulation of cell migration GO:0030334 289 0.054
protein autoubiquitination GO:0051865 37 0.051
negative regulation of protein import into nucleus GO:0042308 30 0.050
Human
regulation of nervous system development GO:0051960 88 0.048
organonitrogen compound biosynthetic process GO:1901566 200 0.048
regulation of neurogenesis GO:0050767 82 0.047
negative regulation of intracellular protein transport GO:0090317 42 0.047
Human
regulation of chromatin assembly GO:0010847 2 0.046
Human
regulation of cytokine production GO:0001817 232 0.045
cellular response to organic cyclic compound GO:0071407 127 0.044
negative regulation of cell differentiation GO:0045596 171 0.044
posttranscriptional regulation of gene expression GO:0010608 213 0.043
carbohydrate derivative biosynthetic process GO:1901137 207 0.043
Human
nuclear import GO:0051170 106 0.042
Human
pattern recognition receptor signaling pathway GO:0002221 48 0.042
cytokine production GO:0001816 247 0.041
nucleoside triphosphate catabolic process GO:0009143 394 0.040
negative regulation of neurogenesis GO:0050768 26 0.039
cellular response to interferon alpha GO:0035457 4 0.039
positive regulation of cytokine production GO:0001819 167 0.039
chromatin modification GO:0016568 298 0.038
protein localization to nucleus GO:0034504 136 0.038
Human
regulation of defense response to virus by host GO:0050691 22 0.037
ncrna metabolic process GO:0034660 108 0.037
cellular response to dsrna GO:0071359 19 0.036
nucleotide biosynthetic process GO:0009165 109 0.035
regulation of immune response GO:0050776 201 0.035
nucleoside triphosphate metabolic process GO:0009141 422 0.034
negative regulation of viral process GO:0048525 66 0.034
Human
negative regulation of fibroblast proliferation GO:0048147 12 0.034
Human
positive regulation of cytoplasmic transport GO:1903651 82 0.033
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.033
positive regulation of cell death GO:0010942 263 0.033
purine containing compound catabolic process GO:0072523 411 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
purine nucleotide catabolic process GO:0006195 405 0.031
protein poly adp ribosylation GO:0070212 3 0.031
Human
activation of innate immune response GO:0002218 55 0.031
nucleotide catabolic process GO:0009166 408 0.030
monosaccharide metabolic process GO:0005996 74 0.030
ribonucleoside monophosphate metabolic process GO:0009161 187 0.029
negative regulation of programmed cell death GO:0043069 321 0.028
purine ribonucleotide catabolic process GO:0009154 404 0.028
cellular response to virus GO:0098586 9 0.028
neurogenesis GO:0022008 169 0.027
ribonucleoprotein complex assembly GO:0022618 78 0.027
cellular response to cytokine stimulus GO:0071345 181 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
purine nucleoside monophosphate metabolic process GO:0009126 186 0.025
protein localization to organelle GO:0033365 280 0.025
Human
nucleoside monophosphate catabolic process GO:0009125 159 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
generation of neurons GO:0048699 152 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
protein oligomerization GO:0051259 173 0.024
purine nucleoside monophosphate catabolic process GO:0009128 158 0.023
regulation of cellular response to stress GO:0080135 244 0.023
response to virus GO:0009615 126 0.023
regulation of protein localization to nucleus GO:1900180 85 0.023
Human
positive regulation of intracellular protein transport GO:0090316 76 0.023
dsrna fragmentation GO:0031050 13 0.023
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
positive regulation of immune effector process GO:0002699 40 0.023
negative regulation of developmental process GO:0051093 247 0.023
positive regulation of notch signaling pathway GO:0045747 6 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.022
positive regulation of innate immune response GO:0045089 79 0.022
negative regulation of notch signaling pathway GO:0045746 10 0.022
hexose metabolic process GO:0019318 55 0.022
negative regulation of apoptotic process GO:0043066 316 0.021
circulatory system development GO:0072359 262 0.021
regulation of proteolysis GO:0030162 293 0.021
regulation of rig i signaling pathway GO:0039535 6 0.021
histone modification GO:0016570 251 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.021
defense response to other organism GO:0098542 129 0.021
lipoprotein metabolic process GO:0042157 42 0.020
cardiovascular system development GO:0072358 262 0.020
cellular response to type i interferon GO:0071357 12 0.020
cellular protein catabolic process GO:0044257 261 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
regulation of transferase activity GO:0051338 355 0.020
regulation of cellular component movement GO:0051270 334 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
purine nucleoside catabolic process GO:0006152 398 0.019
response to oxygen containing compound GO:1901700 369 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
regulation of ribonuclease activity GO:0060700 3 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
mrna metabolic process GO:0016071 175 0.019
membrane organization GO:0061024 292 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.019
regulation of angiogenesis GO:0045765 92 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.018
Human
female gamete generation GO:0007292 2 0.018
protein acylation GO:0043543 138 0.018
regulation of binding GO:0051098 111 0.018
protein monoubiquitination GO:0006513 39 0.018
cellular response to molecule of bacterial origin GO:0071219 62 0.018
negative regulation of cytokine production GO:0001818 82 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.017
positive regulation of proteolysis GO:0045862 142 0.017
neuron differentiation GO:0030182 138 0.017
regulation of chromatin organization GO:1902275 56 0.017
Human
organophosphate catabolic process GO:0046434 430 0.017
single organism membrane organization GO:0044802 268 0.017
regulation of innate immune response GO:0045088 97 0.017
regulation of protein kinase activity GO:0045859 289 0.017
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.017
Human
determination of adult lifespan GO:0008340 2 0.017
multicellular organismal aging GO:0010259 3 0.017
regulation of protein catabolic process GO:0042176 155 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
immune response regulating signaling pathway GO:0002764 97 0.016
positive regulation of intracellular transport GO:0032388 104 0.016
positive regulation of immune response GO:0050778 159 0.016
glycosyl compound catabolic process GO:1901658 413 0.016
positive regulation of transferase activity GO:0051347 227 0.015
atp catabolic process GO:0006200 157 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
nucleoside catabolic process GO:0009164 408 0.015
apoptotic signaling pathway GO:0097190 268 0.015
protein maturation GO:0051604 233 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.015
production of small rna involved in gene silencing by rna GO:0070918 13 0.015
cellular amino acid metabolic process GO:0006520 116 0.015
activation of immune response GO:0002253 114 0.015
positive regulation of defense response GO:0031349 87 0.015
cell fate determination GO:0001709 3 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
positive regulation of protein import into nucleus GO:0042307 46 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 12 0.013
ribonucleoprotein complex biogenesis GO:0022613 116 0.013
negative regulation of cytoplasmic transport GO:1903650 46 0.013
Human
nucleoside phosphate catabolic process GO:1901292 412 0.013
oogenesis GO:0048477 2 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
cellular response to lipid GO:0071396 127 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
multi organism transport GO:0044766 14 0.013
positive regulation of endopeptidase activity GO:0010950 84 0.013
regulation of protein k63 linked ubiquitination GO:1900044 6 0.013
Human
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.012
mapk cascade GO:0000165 288 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
spermatid differentiation GO:0048515 4 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
regulation of notch signaling pathway GO:0008593 18 0.012
cell cycle arrest GO:0007050 71 0.012
cellular response to interferon gamma GO:0071346 24 0.012
mitotic cell cycle process GO:1903047 286 0.012
regulation of kinase activity GO:0043549 314 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
production of sirna involved in rna interference GO:0030422 3 0.012
compound eye development GO:0048749 1 0.012
cellular lipid metabolic process GO:0044255 303 0.012
regulation of locomotion GO:0040012 329 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
Human
positive regulation of apoptotic process GO:0043065 246 0.012
negative regulation of cell cycle GO:0045786 193 0.011
protein localization to membrane GO:0072657 160 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
regulation of cell motility GO:2000145 299 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
glucose metabolic process GO:0006006 45 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
response to radiation GO:0009314 151 0.011
vasculature development GO:0001944 181 0.011
viral transcription GO:0019083 35 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
ion transmembrane transport GO:0034220 338 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
posttranscriptional gene silencing GO:0016441 25 0.011
regulation of response to external stimulus GO:0032101 222 0.010
transmembrane transport GO:0055085 399 0.010
metal ion transport GO:0030001 272 0.010
macrophage fusion GO:0034238 1 0.010
response to molecule of bacterial origin GO:0002237 82 0.010
positive regulation of kinase activity GO:0033674 204 0.010
ncrna processing GO:0034470 83 0.010
mitotic cell cycle GO:0000278 326 0.010
negative regulation of neuron differentiation GO:0045665 21 0.010
negative regulation of immune system process GO:0002683 136 0.010
lipid biosynthetic process GO:0008610 177 0.010

PARP9 disease predictions

Disease DO term ID Size Probability Func Analog Org
cerebrovascular disease DOID:6713 8 0.098
cardiovascular system disease DOID:1287 106 0.098
artery disease DOID:0050828 23 0.098
vascular disease DOID:178 25 0.098
disease of metabolism DOID:0014667 295 0.011
acquired metabolic disease DOID:0060158 58 0.011