Homo sapiens

222 known processes

PAX8

paired box 8

PAX8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.999
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.999
globus pallidus development GO:0021759 1 0.999
forebrain regionalization GO:0021871 3 0.995
regulation of blood volume by renin angiotensin GO:0002016 1 0.990
forebrain dorsal ventral pattern formation GO:0021798 1 0.984
neuron fate commitment GO:0048663 2 0.980
Fly
menstrual cycle phase GO:0022601 2 0.961
gabaergic neuron differentiation GO:0097154 1 0.944
cardiac right ventricle morphogenesis GO:0003215 3 0.929
mesonephric duct development GO:0072177 3 0.917
paramesonephric duct development GO:0061205 2 0.862
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.832
specification of organ identity GO:0010092 3 0.812
Mouse
endocrine system development GO:0035270 26 0.800
forebrain generation of neurons GO:0021872 3 0.755
response to salt stress GO:0009651 3 0.731
locomotory behavior GO:0007626 1 0.666
branching morphogenesis of an epithelial tube GO:0048754 19 0.664
system process GO:0003008 349 0.659
kidney development GO:0001822 53 0.653
circulatory system development GO:0072359 262 0.637
regulation of cell motility GO:2000145 299 0.615
positive regulation of developmental process GO:0051094 314 0.611
Mouse
response to oxygen containing compound GO:1901700 369 0.610
outflow tract septum morphogenesis GO:0003148 4 0.591
mesenchyme development GO:0060485 59 0.581
cardiovascular system development GO:0072358 262 0.571
renal tubule development GO:0061326 19 0.565
organ morphogenesis GO:0009887 147 0.563
negative regulation of stem cell differentiation GO:2000737 22 0.543
Mouse
regulation of cell differentiation GO:0045595 393 0.510
Mouse Fly
negative regulation of cell death GO:0060548 345 0.500
Human Mouse
endocrine process GO:0050886 25 0.487
kidney epithelium development GO:0072073 25 0.484
pituitary gland development GO:0021983 2 0.471
lung alveolus development GO:0048286 4 0.468
epithelium development GO:0060429 227 0.464
cellular lipid metabolic process GO:0044255 303 0.451
positive regulation of cell differentiation GO:0045597 211 0.440
Mouse
tube development GO:0035295 125 0.438
negative regulation of apoptotic process GO:0043066 316 0.438
Human Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.431
Zebrafish Mouse
limbic system development GO:0021761 3 0.415
septum secundum development GO:0003285 2 0.413
negative regulation of cellular component movement GO:0051271 106 0.406
regulation of locomotion GO:0040012 329 0.402
forebrain neuron differentiation GO:0021879 3 0.395
regulation of systemic arterial blood pressure by hormone GO:0001990 12 0.391
epithelial cell differentiation GO:0030855 141 0.385
cardiac conduction system development GO:0003161 2 0.384
response to growth factor GO:0070848 205 0.383
tissue morphogenesis GO:0048729 96 0.382
ureteric bud development GO:0001657 13 0.367
cellular response to endogenous stimulus GO:0071495 336 0.358
mesenchymal cell development GO:0014031 50 0.351
cell development GO:0048468 328 0.347
nervous system development GO:0007399 293 0.346
behavior GO:0007610 112 0.343
negative regulation of programmed cell death GO:0043069 321 0.342
Human Mouse
small gtpase mediated signal transduction GO:0007264 78 0.342
organ formation GO:0048645 3 0.339
Mouse
positive regulation of cell proliferation GO:0008284 301 0.339
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.339
regulation of cell migration GO:0030334 289 0.338
cell cell signaling GO:0007267 155 0.335
lipid metabolic process GO:0006629 381 0.327
cerebral cortex cell migration GO:0021795 3 0.321
nephron morphogenesis GO:0072028 15 0.318
negative regulation of multicellular organismal process GO:0051241 317 0.315
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.306
regulation of anatomical structure morphogenesis GO:0022603 286 0.303
Mouse Fly
cation transport GO:0006812 331 0.303
response to lipid GO:0033993 206 0.299
nephron epithelium morphogenesis GO:0072088 15 0.298
cellular ion homeostasis GO:0006873 168 0.294
calcium ion homeostasis GO:0055074 122 0.293
head development GO:0060322 108 0.291
enzyme linked receptor protein signaling pathway GO:0007167 303 0.289
response to hormone GO:0009725 175 0.287
cellular response to growth factor stimulus GO:0071363 197 0.286
regulation of cellular component movement GO:0051270 334 0.284
striated muscle cell apoptotic process GO:0010658 3 0.282
renal system development GO:0072001 63 0.273
regulation of dermatome development GO:0061183 3 0.269
blood circulation GO:0008015 113 0.257
cation homeostasis GO:0055080 189 0.254
chemotaxis GO:0006935 157 0.253
regulation of hormone levels GO:0010817 125 0.252
negative regulation of developmental process GO:0051093 247 0.245
Mouse
cell projection organization GO:0030030 252 0.244
Fly
negative regulation of locomotion GO:0040013 118 0.242
lung saccule development GO:0060430 2 0.240
mesonephros development GO:0001823 17 0.237
heart morphogenesis GO:0003007 48 0.235
negative regulation of cell differentiation GO:0045596 171 0.228
Mouse
taxis GO:0042330 157 0.220
mapk cascade GO:0000165 288 0.214
cellular component morphogenesis GO:0032989 314 0.212
positive regulation of nucleotide metabolic process GO:0045981 230 0.210
cation transmembrane transport GO:0098655 238 0.210
ureteric bud morphogenesis GO:0060675 10 0.204
positive regulation of locomotion GO:0040017 186 0.201
positive regulation of odontogenesis GO:0042482 3 0.192
divalent inorganic cation homeostasis GO:0072507 136 0.192
endoderm development GO:0007492 33 0.187
muscle tissue development GO:0060537 62 0.187
hindbrain development GO:0030902 3 0.186
kidney morphogenesis GO:0060993 19 0.185
negative regulation of cell migration GO:0030336 102 0.181
brain development GO:0007420 97 0.178
cardiac atrium development GO:0003230 10 0.177
negative regulation of cell development GO:0010721 48 0.176
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.176
glycine import GO:0036233 1 0.173
regulation of testosterone biosynthetic process GO:2000224 2 0.171
negative regulation of male gonad development GO:2000019 1 0.169
post embryonic development GO:0009791 2 0.169
Worm
mesenchymal cell differentiation GO:0048762 52 0.168
metal ion homeostasis GO:0055065 169 0.167
micturition GO:0060073 3 0.166
central nervous system development GO:0007417 123 0.164
response to abiotic stimulus GO:0009628 336 0.161
positive regulation of protein phosphorylation GO:0001934 313 0.160
cardiac muscle tissue development GO:0048738 39 0.158
metanephros development GO:0001656 16 0.157
response to alcohol GO:0097305 64 0.157
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 12 0.155
nephric duct development GO:0072176 4 0.155
morphogenesis of an epithelium GO:0002009 60 0.153
cellular chemical homeostasis GO:0055082 180 0.153
regionalization GO:0003002 29 0.150
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.149
regulation of transmembrane transport GO:0034762 139 0.148
cellular divalent inorganic cation homeostasis GO:0072503 128 0.147
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.146
muscle organ development GO:0007517 56 0.146
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.145
regulation of cardiac muscle cell apoptotic process GO:0010665 3 0.145
nucleoside triphosphate metabolic process GO:0009141 422 0.144
transmembrane transport GO:0055085 399 0.144
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.144
Mouse
forebrain development GO:0030900 26 0.141
striated muscle tissue development GO:0014706 59 0.140
cell type specific apoptotic process GO:0097285 125 0.137
Mouse
positive regulation of epithelial cell proliferation GO:0050679 65 0.136
Human
positive regulation of phosphorylation GO:0042327 394 0.134
inner ear morphogenesis GO:0042472 4 0.133
Zebrafish Mouse
organonitrogen compound biosynthetic process GO:1901566 200 0.133
inorganic cation transmembrane transport GO:0098662 194 0.132
metal ion transport GO:0030001 272 0.132
ras protein signal transduction GO:0007265 73 0.131
epithelial tube morphogenesis GO:0060562 38 0.131
negative regulation of cardiac muscle cell apoptotic process GO:0010667 2 0.131
neuron projection development GO:0031175 106 0.130
Fly
segmentation GO:0035282 4 0.130
epithelial to mesenchymal transition GO:0001837 48 0.129
cellular homeostasis GO:0019725 196 0.128
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.126
spinal cord development GO:0021510 4 0.125
chemical homeostasis GO:0048878 306 0.125
cellular metal ion homeostasis GO:0006875 146 0.123
cell morphogenesis GO:0000902 296 0.122
stem cell development GO:0048864 69 0.121
Mouse
cellular amino acid metabolic process GO:0006520 116 0.121
morphogenesis of a branching epithelium GO:0061138 20 0.120
nephron tubule development GO:0072080 17 0.119
heart development GO:0007507 95 0.119
response to organic cyclic compound GO:0014070 204 0.119
associative learning GO:0008306 1 0.118
negative regulation of cell motility GO:2000146 104 0.118
organic hydroxy compound metabolic process GO:1901615 147 0.118
dermatome development GO:0061054 3 0.117
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.116
embryonic organ development GO:0048568 36 0.114
Zebrafish Mouse
circulatory system process GO:0003013 113 0.114
mesonephric epithelium development GO:0072163 14 0.113
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.111
Mouse
positive regulation of nucleotide catabolic process GO:0030813 185 0.111
blood vessel development GO:0001568 172 0.110
neurogenesis GO:0022008 169 0.110
Fly
male sex differentiation GO:0046661 25 0.109
Worm
negative regulation of testosterone biosynthetic process GO:2000225 1 0.109
mesonephric tubule formation GO:0072172 1 0.108
regulation of purine nucleotide metabolic process GO:1900542 264 0.108
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.107
purine ribonucleoside metabolic process GO:0046128 437 0.107
positive regulation of nucleoside metabolic process GO:0045979 186 0.106
negative regulation of testicular blood vessel morphogenesis GO:0061369 1 0.105
regulation of cell morphogenesis GO:0022604 153 0.104
Mouse
negative regulation of myotube differentiation GO:0010832 4 0.104
positive regulation of cell motility GO:2000147 177 0.103
immune system development GO:0002520 195 0.103
cell fate determination GO:0001709 3 0.103
lung development GO:0030324 20 0.102
cellular cation homeostasis GO:0030003 163 0.102
cellular potassium ion transport GO:0071804 60 0.101
tube morphogenesis GO:0035239 95 0.101
signal transduction by phosphorylation GO:0023014 297 0.101
phospholipid metabolic process GO:0006644 99 0.101
ion homeostasis GO:0050801 230 0.100
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.100
ribonucleoside catabolic process GO:0042454 406 0.099
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.099
cellular amine metabolic process GO:0044106 41 0.099
regulation of neurogenesis GO:0050767 82 0.098
Fly
cytosolic calcium ion homeostasis GO:0051480 89 0.098
regulation of purine nucleotide catabolic process GO:0033121 205 0.096
peptide secretion GO:0002790 51 0.096
cell differentiation in spinal cord GO:0021515 1 0.096
positive regulation of cortisol biosynthetic process GO:2000066 1 0.095
cell morphogenesis involved in differentiation GO:0000904 144 0.095
actin filament based process GO:0030029 224 0.095
wnt signaling pathway GO:0016055 156 0.094
response to external biotic stimulus GO:0043207 261 0.094
positive regulation of kinase activity GO:0033674 204 0.093
cartilage condensation GO:0001502 1 0.093
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.092
organophosphate catabolic process GO:0046434 430 0.091
regulation of mesonephros development GO:0061217 3 0.091
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.090
positive regulation of catabolic process GO:0009896 310 0.090
regulation of cell development GO:0060284 161 0.089
Mouse Fly
positive regulation of cellular catabolic process GO:0031331 284 0.089
branching involved in ureteric bud morphogenesis GO:0001658 9 0.089
regulation of muscle cell differentiation GO:0051147 31 0.089
regulation of mapk cascade GO:0043408 262 0.088
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.088
response to nitrogen compound GO:1901698 184 0.088
lung morphogenesis GO:0060425 6 0.087
nephron epithelium development GO:0072009 23 0.087
cellular response to oxygen containing compound GO:1901701 276 0.086
positive regulation of ras gtpase activity GO:0032320 117 0.086
purine nucleoside triphosphate metabolic process GO:0009144 412 0.085
regulation of blood pressure GO:0008217 30 0.084
g protein coupled receptor signaling pathway GO:0007186 207 0.084
development of primary male sexual characteristics GO:0046546 23 0.084
positive regulation of cellular amine metabolic process GO:0033240 7 0.083
mesonephric tubule morphogenesis GO:0072171 10 0.083
regulation of cell cycle GO:0051726 393 0.082
embryonic epithelial tube formation GO:0001838 4 0.082
Mouse
hyperosmotic response GO:0006972 4 0.082
purine ribonucleoside catabolic process GO:0046130 398 0.082
regulation of small gtpase mediated signal transduction GO:0051056 156 0.082
digestive system development GO:0055123 75 0.082
ventricular septum morphogenesis GO:0060412 3 0.081
positive regulation of nervous system development GO:0051962 54 0.081
male gonad development GO:0008584 23 0.081
positive regulation of tooth mineralization GO:0070172 2 0.081
positive regulation of protein kinase activity GO:0045860 190 0.080
nephron development GO:0072006 30 0.080
generation of neurons GO:0048699 152 0.080
Fly
regulation of epithelial to mesenchymal transition GO:0010717 37 0.080
secretion by cell GO:0032940 226 0.079
hormone secretion GO:0046879 65 0.079
regulation of kinase activity GO:0043549 314 0.077
purine nucleotide catabolic process GO:0006195 405 0.077
hormone metabolic process GO:0042445 61 0.077
neuron differentiation GO:0030182 138 0.076
Fly
regulation of nervous system development GO:0051960 88 0.076
Fly
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.075
response to other organism GO:0051707 261 0.075
positive regulation of hydrolase activity GO:0051345 331 0.075
single organism reproductive process GO:0044702 98 0.075
Worm
regulation of epithelial cell proliferation GO:0050678 113 0.074
Human
nucleoside phosphate catabolic process GO:1901292 412 0.074
ribonucleoside triphosphate catabolic process GO:0009203 391 0.074
renal tubule morphogenesis GO:0061333 14 0.073
response to biotic stimulus GO:0009607 276 0.073
nephron tubule morphogenesis GO:0072078 13 0.073
negative regulation of epithelial to mesenchymal transition GO:0010719 14 0.073
secretion GO:0046903 254 0.072
guanosine containing compound metabolic process GO:1901068 244 0.071
cell projection morphogenesis GO:0048858 129 0.071
Fly
regulation of secretion GO:0051046 194 0.071
nitrogen compound transport GO:0071705 191 0.070
rho protein signal transduction GO:0007266 26 0.070
ribonucleotide catabolic process GO:0009261 405 0.070
wnt signaling pathway involved in wound healing spreading of epidermal cells GO:0035659 1 0.070
limb bud formation GO:0060174 1 0.070
ribonucleoside triphosphate metabolic process GO:0009199 412 0.069
response to organonitrogen compound GO:0010243 156 0.069
membrane organization GO:0061024 292 0.069
gland development GO:0048732 48 0.069
hippocampus development GO:0021766 1 0.068
positive regulation of glucocorticoid metabolic process GO:0031945 1 0.068
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.068
reproductive process GO:0022414 106 0.068
Worm
organic hydroxy compound transport GO:0015850 63 0.068
multicellular organismal response to stress GO:0033555 1 0.068
regulation of transferase activity GO:0051338 355 0.068
embryonic morphogenesis GO:0048598 85 0.068
Zebrafish Mouse
nucleotide catabolic process GO:0009166 408 0.068
positive regulation of mapk cascade GO:0043410 190 0.068
gtp catabolic process GO:0006184 237 0.067
embryonic forelimb morphogenesis GO:0035115 4 0.067
striated muscle cell differentiation GO:0051146 43 0.067
negative regulation of cellular component organization GO:0051129 235 0.067
pattern specification involved in kidney development GO:0061004 1 0.066
Mouse
embryo development GO:0009790 123 0.065
Zebrafish Mouse Worm
regulation of ras gtpase activity GO:0032318 128 0.065
ion transmembrane transport GO:0034220 338 0.065
heart formation GO:0060914 2 0.064
regulation of ion transmembrane transport GO:0034765 132 0.064
positive regulation of transferase activity GO:0051347 227 0.064
regulation of cell cycle process GO:0010564 266 0.064
stem cell differentiation GO:0048863 93 0.064
Mouse
hair follicle morphogenesis GO:0031069 2 0.064
cytoplasmic transport GO:0016482 379 0.063
nucleoside triphosphate catabolic process GO:0009143 394 0.062
positive regulation of mesonephros development GO:0061213 2 0.062
Mouse
regulation of odontogenesis GO:0042481 4 0.062
cardiac atrium morphogenesis GO:0003209 7 0.062
cardiac chamber morphogenesis GO:0003206 26 0.062
cardiac ventricle morphogenesis GO:0003208 20 0.062
regulation of system process GO:0044057 101 0.061
dorsal ventral pattern formation GO:0009953 15 0.061
regulation of nucleotide metabolic process GO:0006140 269 0.061
regulation of striated muscle cell differentiation GO:0051153 25 0.059
nucleoside catabolic process GO:0009164 408 0.059
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.059
mesonephric tubule development GO:0072164 14 0.059
muscle structure development GO:0061061 98 0.058
Fly
lung epithelium development GO:0060428 7 0.058
developmental programmed cell death GO:0010623 3 0.057
Mouse
epidermis morphogenesis GO:0048730 3 0.057
glycosyl compound catabolic process GO:1901658 413 0.057
reproductive system development GO:0061458 56 0.057
Worm
regulation of ras protein signal transduction GO:0046578 155 0.057
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.057
neural nucleus development GO:0048857 47 0.057
regulation of organ morphogenesis GO:2000027 24 0.057
Mouse Fly
regulation of nucleotide catabolic process GO:0030811 205 0.056
regulation of behavior GO:0050795 82 0.056
cell fate commitment GO:0045165 27 0.056
Worm Fly
cell adhesion GO:0007155 325 0.056
regulation of protein kinase activity GO:0045859 289 0.056
erk1 and erk2 cascade GO:0070371 104 0.055
atrial septum morphogenesis GO:0060413 5 0.055
potassium ion transmembrane transport GO:0071805 60 0.055
heart field specification GO:0003128 2 0.055
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.054
organophosphate biosynthetic process GO:0090407 163 0.054
regulation of neuron differentiation GO:0045664 70 0.054
Fly
canonical wnt signaling pathway GO:0060070 116 0.054
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.054
neurological system process GO:0050877 163 0.054
cell part morphogenesis GO:0032990 137 0.054
Fly
regulation of nucleoside metabolic process GO:0009118 209 0.053
biological adhesion GO:0022610 331 0.053
keratinocyte differentiation GO:0030216 36 0.053
hindlimb morphogenesis GO:0035137 2 0.052
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.052
regulation of gtp catabolic process GO:0033124 180 0.052
regulation of wnt signaling pathway GO:0030111 123 0.052
mesodermal cell fate specification GO:0007501 2 0.052
positive regulation of cellular component organization GO:0051130 376 0.052
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.052
negative regulation of muscle cell differentiation GO:0051148 17 0.051
activation of protein kinase activity GO:0032147 90 0.051
telencephalon development GO:0021537 17 0.051
positive regulation of glucocorticoid biosynthetic process GO:0031948 1 0.051
actin cytoskeleton organization GO:0030036 207 0.050
inorganic ion transmembrane transport GO:0098660 231 0.050
lung epithelial cell differentiation GO:0060487 1 0.050
guanosine containing compound catabolic process GO:1901069 239 0.050
regulation of cellular component biogenesis GO:0044087 281 0.049
muscle tissue morphogenesis GO:0060415 19 0.049
visual behavior GO:0007632 2 0.049
regulation of ion transport GO:0043269 189 0.049
negative regulation of catalytic activity GO:0043086 335 0.048
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.048
muscle organ morphogenesis GO:0048644 19 0.048
blood vessel morphogenesis GO:0048514 162 0.048
action potential GO:0001508 34 0.048
purine nucleoside catabolic process GO:0006152 398 0.048
ribonucleotide biosynthetic process GO:0009260 81 0.048
synaptic transmission glycinergic GO:0060012 1 0.048
regulation of protein serine threonine kinase activity GO:0071900 179 0.048
drinking behavior GO:0042756 1 0.048
cellular calcium ion homeostasis GO:0006874 117 0.047
muscle cell differentiation GO:0042692 63 0.047
signal release GO:0023061 70 0.047
cell aggregation GO:0098743 1 0.046
urogenital system development GO:0001655 65 0.046
response to lipopolysaccharide GO:0032496 70 0.046
determination of adult lifespan GO:0008340 2 0.046
positive regulation of cellular component movement GO:0051272 181 0.046
potassium ion transport GO:0006813 62 0.045
regulation of metanephros size GO:0035566 1 0.045
Human
purine ribonucleotide biosynthetic process GO:0009152 79 0.044
angiogenesis GO:0001525 147 0.043
cardiac muscle cell apoptotic process GO:0010659 3 0.043
cell proliferation in forebrain GO:0021846 1 0.043
small molecule biosynthetic process GO:0044283 157 0.043
regulation of cellular amino acid metabolic process GO:0006521 6 0.042
cardiac muscle tissue morphogenesis GO:0055008 18 0.042
regulation of gtpase activity GO:0043087 180 0.042
protein localization to plasma membrane GO:0072659 93 0.042
hormone transport GO:0009914 68 0.041
negative regulation of voltage gated calcium channel activity GO:1901386 4 0.041
cloacal septation GO:0060197 1 0.041
cellular response to organic cyclic compound GO:0071407 127 0.041
positive regulation of cell migration GO:0030335 172 0.041
morphogenesis of a branching structure GO:0001763 21 0.041
cellular response to hormone stimulus GO:0032870 125 0.041
response to molecule of bacterial origin GO:0002237 82 0.041
cellular response to organonitrogen compound GO:0071417 124 0.041
response to wounding GO:0009611 168 0.041
response to fibroblast growth factor GO:0071774 39 0.040
leukocyte migration GO:0050900 107 0.040
cerebral cortex development GO:0021987 10 0.040
lung cell differentiation GO:0060479 1 0.040
developmental process involved in reproduction GO:0003006 66 0.040
Worm
positive regulation of aldosterone metabolic process GO:0032346 2 0.040
respiratory tube development GO:0030323 20 0.040
neuron projection morphogenesis GO:0048812 50 0.040
Fly
gtp metabolic process GO:0046039 239 0.040
regulation of striated muscle cell apoptotic process GO:0010662 3 0.040
regulation of myotube differentiation GO:0010830 18 0.039
epidermis development GO:0008544 59 0.039
neuron development GO:0048666 113 0.039
Fly
multicellular organismal aging GO:0010259 3 0.039
endomembrane system organization GO:0010256 196 0.039
cerebral cortex neuron differentiation GO:0021895 1 0.039
regulation of systemic arterial blood pressure GO:0003073 19 0.038
metencephalon development GO:0022037 2 0.038
circadian behavior GO:0048512 2 0.038
regulation of male gonad development GO:2000018 4 0.038
regulation of cellular response to growth factor stimulus GO:0090287 76 0.038
positive regulation of synaptic transmission GO:0050806 4 0.038
cardiac septum morphogenesis GO:0060411 9 0.038
epidermal cell differentiation GO:0009913 45 0.038
skin development GO:0043588 76 0.038
positive regulation of cell death GO:0010942 263 0.038
lipid biosynthetic process GO:0008610 177 0.038
positive regulation of gtpase activity GO:0043547 166 0.037
sodium independent organic anion transport GO:0043252 2 0.037
telencephalon cell migration GO:0022029 4 0.037
anterior posterior axis specification GO:0009948 2 0.037
organic anion transport GO:0015711 103 0.037
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.037
pattern specification process GO:0007389 43 0.037
Mouse
vesicle mediated transport GO:0016192 371 0.037
reactive nitrogen species metabolic process GO:2001057 3 0.037
cellular ketone metabolic process GO:0042180 80 0.037
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.037
Fly
female gamete generation GO:0007292 2 0.036
purine containing compound biosynthetic process GO:0072522 88 0.036
protein processing GO:0016485 226 0.036
Human
visual learning GO:0008542 1 0.036
synaptic transmission involved in micturition GO:0060084 2 0.036
bone mineralization GO:0030282 34 0.036
nucleoside phosphate biosynthetic process GO:1901293 109 0.036
vasculature development GO:0001944 181 0.036
positive regulation of neurogenesis GO:0050769 49 0.035
respiratory system development GO:0060541 22 0.035
motor neuron axon guidance GO:0008045 2 0.035
somatostatin signaling pathway GO:0038170 1 0.035
axonogenesis GO:0007409 31 0.035
regulation of peptidase activity GO:0052547 180 0.035
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.035
response to estrogen GO:0043627 47 0.035
purine nucleoside monophosphate catabolic process GO:0009128 158 0.035
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.035
single organism cellular localization GO:1902580 332 0.035
response to disaccharide GO:0034285 1 0.034
regulation of body fluid levels GO:0050878 99 0.034
positive regulation of neuron differentiation GO:0045666 40 0.034
purine containing compound catabolic process GO:0072523 411 0.034
regulation of cellular amine metabolic process GO:0033238 11 0.034
renal vesicle morphogenesis GO:0072077 4 0.034
response to cytokine GO:0034097 232 0.034
morphogenesis of embryonic epithelium GO:0016331 4 0.033
Mouse
response to ethanol GO:0045471 11 0.033
postsynaptic membrane organization GO:0001941 2 0.033
response to transforming growth factor beta GO:0071559 94 0.033
regulation of hormone secretion GO:0046883 57 0.033
regulation of membrane potential GO:0042391 95 0.033
negative regulation of striated muscle cell differentiation GO:0051154 8 0.033
somatostatin receptor signaling pathway GO:0038169 1 0.033
sex differentiation GO:0007548 45 0.033
Worm
organic hydroxy compound biosynthetic process GO:1901617 71 0.033
regulation of cyclase activity GO:0031279 19 0.033
cellular response to dna damage stimulus GO:0006974 379 0.033
cardiac cell fate determination GO:0060913 3 0.032

PAX8 disease predictions

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 11 0.122
kidney disease DOID:557 36 0.122
Human
urinary system disease DOID:18 40 0.122
Human
cancer DOID:162 167 0.071
Human
disease of cellular proliferation DOID:14566 174 0.071
Human
sensory system disease DOID:0050155 203 0.060
nervous system disease DOID:863 431 0.060
disease of metabolism DOID:0014667 295 0.057
organ system cancer DOID:0050686 164 0.048
Human
eye and adnexa disease DOID:1492 150 0.040