Homo sapiens

135 known processes

PAXIP1

PAX interacting (with transcription-activation domain) protein 1

(Aliases: PACIP1,PAXIP1L,FLJ41049,CAGF29,TNRC2,PTIP)

PAXIP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone methylation GO:0016571 60 0.999
histone h3 k4 methylation GO:0051568 27 0.999
chromatin modification GO:0016568 298 0.997
histone modification GO:0016570 251 0.996
histone lysine methylation GO:0034968 50 0.994
chromatin organization GO:0006325 351 0.989
protein alkylation GO:0008213 74 0.940
internal protein amino acid acetylation GO:0006475 101 0.887
Mouse
histone h3 acetylation GO:0043966 45 0.880
methylation GO:0032259 106 0.818
peptidyl lysine methylation GO:0018022 37 0.742
post embryonic development GO:0009791 2 0.719
covalent chromatin modification GO:0016569 254 0.711
cellular response to dna damage stimulus GO:0006974 379 0.685
protein methylation GO:0006479 74 0.594
internal peptidyl lysine acetylation GO:0018393 97 0.576
Mouse
negative regulation of cell cycle process GO:0010948 121 0.508
mitotic cell cycle GO:0000278 326 0.474
protein acylation GO:0043543 138 0.457
Mouse
chromosome segregation GO:0007059 114 0.454
cell cycle checkpoint GO:0000075 117 0.426
protein acetylation GO:0006473 116 0.417
Mouse
oocyte development GO:0048599 1 0.391
female gamete generation GO:0007292 2 0.364
cell projection organization GO:0030030 252 0.361
peptidyl lysine modification GO:0018205 144 0.315
Mouse
segmentation GO:0035282 4 0.314
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.279
oogenesis GO:0048477 2 0.265
mitotic cell cycle process GO:1903047 286 0.259
reproductive process GO:0022414 106 0.223
mitotic nuclear division GO:0007067 119 0.218
regulation of chromosome segregation GO:0051983 44 0.215
sister chromatid segregation GO:0000819 54 0.213
regulation of cellular component biogenesis GO:0044087 281 0.200
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.192
single organism reproductive process GO:0044702 98 0.183
response to estrogen GO:0043627 47 0.182
regulation of chromosome organization GO:0033044 103 0.179
Mouse
embryo development GO:0009790 123 0.177
Fly
determination of adult lifespan GO:0008340 2 0.167
mitotic sister chromatid segregation GO:0000070 53 0.150
positive regulation of cell proliferation GO:0008284 301 0.149
oocyte differentiation GO:0009994 2 0.148
organelle fission GO:0048285 149 0.139
regulation of mitotic cell cycle GO:0007346 189 0.138
regulation of meiotic cell cycle GO:0051445 4 0.136
reproductive structure development GO:0048608 55 0.135
macromolecule methylation GO:0043414 97 0.119
negative regulation of cell cycle GO:0045786 193 0.117
cellular component morphogenesis GO:0032989 314 0.116
mitotic cell cycle phase transition GO:0044772 162 0.113
nervous system development GO:0007399 293 0.111
response to lipid GO:0033993 206 0.103
histone h4 k8 acetylation GO:0043982 15 0.101
rna processing GO:0006396 255 0.100
purine nucleoside triphosphate metabolic process GO:0009144 412 0.100
histone acetylation GO:0016573 93 0.099
Mouse
chromosome separation GO:0051304 23 0.092
regulation of dna templated transcription elongation GO:0032784 23 0.090
regulation of cell cycle process GO:0010564 266 0.089
regulation of gene expression epigenetic GO:0040029 73 0.088
ribonucleotide catabolic process GO:0009261 405 0.088
multicellular organismal aging GO:0010259 3 0.087
cellular amino acid metabolic process GO:0006520 116 0.086
regulation of cellular ketone metabolic process GO:0010565 50 0.083
response to steroid hormone GO:0048545 80 0.083
cell projection morphogenesis GO:0048858 129 0.079
positive regulation of growth GO:0045927 58 0.070
Worm
reproductive system development GO:0061458 56 0.064
cardiovascular system development GO:0072358 262 0.064
Mouse
regulation of protein localization GO:0032880 296 0.063
dna templated transcription initiation GO:0006352 35 0.063
embryo development ending in birth or egg hatching GO:0009792 34 0.061
response to organic cyclic compound GO:0014070 204 0.060
ubiquitin dependent protein catabolic process GO:0006511 206 0.054
dna packaging GO:0006323 77 0.053
ribonucleoside catabolic process GO:0042454 406 0.051
regulation of cell division GO:0051302 116 0.051
negative regulation of cellular protein catabolic process GO:1903363 38 0.050
negative regulation of organelle organization GO:0010639 126 0.049
intracellular estrogen receptor signaling pathway GO:0030520 23 0.047
dna replication GO:0006260 116 0.046
dna repair GO:0006281 198 0.046
cell development GO:0048468 328 0.045
developmental process involved in reproduction GO:0003006 66 0.044
negative regulation of chromosome organization GO:2001251 48 0.042
circulatory system development GO:0072359 262 0.042
Mouse
protein catabolic process GO:0030163 325 0.042
regulation of growth GO:0040008 165 0.042
Worm
regulation of protein transport GO:0051223 213 0.040
vesicle mediated transport GO:0016192 371 0.039
metaphase anaphase transition of cell cycle GO:0044784 21 0.039
growth GO:0040007 202 0.039
Worm
cellular response to oxygen containing compound GO:1901701 276 0.038
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.038
negative regulation of protein maturation GO:1903318 142 0.038
purine nucleotide catabolic process GO:0006195 405 0.038
immune system development GO:0002520 195 0.037
Mouse
sex differentiation GO:0007548 45 0.036
dna conformation change GO:0071103 113 0.036
mitotic cell cycle checkpoint GO:0007093 68 0.036
nuclear division GO:0000280 128 0.036
anterior posterior axis specification GO:0009948 2 0.036
cellular ketone metabolic process GO:0042180 80 0.036
single organism cellular localization GO:1902580 332 0.034
development of primary sexual characteristics GO:0045137 35 0.034
locomotory behavior GO:0007626 1 0.034
central nervous system development GO:0007417 123 0.034
organophosphate catabolic process GO:0046434 430 0.034
cytokine production GO:0001816 247 0.034
regulation of response to dna damage stimulus GO:2001020 94 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.033
cell morphogenesis GO:0000902 296 0.033
nucleoside monophosphate catabolic process GO:0009125 159 0.032
regulation of protein processing GO:0070613 150 0.032
generation of neurons GO:0048699 152 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.032
meiotic chromosome segregation GO:0045132 4 0.031
regulation of sister chromatid segregation GO:0033045 27 0.031
ras protein signal transduction GO:0007265 73 0.031
protein localization to organelle GO:0033365 280 0.030
nucleoside monophosphate metabolic process GO:0009123 191 0.030
blastocyst development GO:0001824 3 0.030
negative regulation of proteolysis GO:0045861 132 0.029
regulation of cell cycle phase transition GO:1901987 126 0.029
modification dependent protein catabolic process GO:0019941 209 0.028
regulation of nuclear division GO:0051783 65 0.028
dna dependent dna replication GO:0006261 44 0.028
cell part morphogenesis GO:0032990 137 0.027
taxis GO:0042330 157 0.027
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.025
maintenance of protein location in cell GO:0032507 56 0.024
multi multicellular organism process GO:0044706 18 0.024
hematopoietic or lymphoid organ development GO:0048534 186 0.024
cell division GO:0051301 168 0.024
reproduction GO:0000003 63 0.024
regionalization GO:0003002 29 0.023
Fly
protein processing GO:0016485 226 0.023
response to hormone GO:0009725 175 0.023
chordate embryonic development GO:0043009 34 0.023
negative regulation of programmed cell death GO:0043069 321 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
mrna metabolic process GO:0016071 175 0.023
cellular response to organonitrogen compound GO:0071417 124 0.023
positive regulation of protein transport GO:0051222 135 0.022
regulation of mitotic cell cycle phase transition GO:1901990 118 0.022
multicellular organismal reproductive process GO:0048609 40 0.022
amine metabolic process GO:0009308 44 0.022
glycosyl compound catabolic process GO:1901658 413 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
regulation of meiosis GO:0040020 3 0.021
negative regulation of mitotic cell cycle GO:0045930 102 0.021
purine containing compound catabolic process GO:0072523 411 0.021
cell morphogenesis involved in differentiation GO:0000904 144 0.021
maintenance of protein location GO:0045185 57 0.021
atp catabolic process GO:0006200 157 0.021
chromatin assembly or disassembly GO:0006333 78 0.021
negative regulation of hydrolase activity GO:0051346 182 0.020
regulation of cellular protein catabolic process GO:1903362 96 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.020
nucleoside catabolic process GO:0009164 408 0.020
positive regulation of programmed cell death GO:0043068 249 0.019
transdifferentiation GO:0060290 2 0.019
dendrite development GO:0016358 24 0.019
negative regulation of cellular catabolic process GO:0031330 83 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.018
intracellular mrna localization GO:0008298 1 0.018
compound eye development GO:0048749 1 0.018
cellular response to abiotic stimulus GO:0071214 117 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
behavior GO:0007610 112 0.017
purine nucleoside catabolic process GO:0006152 398 0.016
maintenance of location in cell GO:0051651 62 0.016
spindle checkpoint GO:0031577 26 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
histone h4 k5 acetylation GO:0043981 15 0.016
organelle assembly GO:0070925 176 0.016
regulation of protein maturation GO:1903317 150 0.016
double strand break repair GO:0006302 101 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
regulation of proteolysis GO:0030162 293 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
intracellular receptor signaling pathway GO:0030522 104 0.015
vasculature development GO:0001944 181 0.015
Mouse
immune response GO:0006955 307 0.015
Mouse Fly
regulation of mitosis GO:0007088 63 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
regulation of defense response GO:0031347 154 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
mitotic spindle checkpoint GO:0071174 18 0.014
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.014
mitotic sister chromatid separation GO:0051306 18 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
mrna processing GO:0006397 133 0.013
regulation of protein catabolic process GO:0042176 155 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
primary neural tube formation GO:0014020 3 0.013
lens development in camera type eye GO:0002088 2 0.013
head development GO:0060322 108 0.013
chemotaxis GO:0006935 157 0.013
dna templated transcription elongation GO:0006354 25 0.013
negative regulation of gene expression epigenetic GO:0045814 19 0.012
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.012
multicellular organism reproduction GO:0032504 42 0.012
microtubule based process GO:0007017 210 0.012
response to ionizing radiation GO:0010212 65 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
protein oligomerization GO:0051259 173 0.012
negative regulation of cell cycle phase transition GO:1901988 89 0.012
negative regulation of sister chromatid segregation GO:0033046 17 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
endocytosis GO:0006897 159 0.011
cell cell signaling GO:0007267 155 0.011
regulation of mitotic sister chromatid separation GO:0010965 27 0.011
secretion by cell GO:0032940 226 0.011
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.011
tissue morphogenesis GO:0048729 96 0.011
ribonucleoside monophosphate catabolic process GO:0009158 158 0.011
neuron projection development GO:0031175 106 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.011
negative regulation of protein processing GO:0010955 142 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
peptidyl lysine acetylation GO:0018394 101 0.011
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.010
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
positive regulation of cellular component organization GO:0051130 376 0.010
chromatin silencing GO:0006342 12 0.010
gamete generation GO:0007276 25 0.010
cell cycle phase transition GO:0044770 173 0.010
regulation of dna metabolic process GO:0051052 153 0.010
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.010

PAXIP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 70 0.034
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
musculoskeletal system disease DOID:17 223 0.012
disease of cellular proliferation DOID:14566 174 0.012
neurodegenerative disease DOID:1289 102 0.008
dementia DOID:1307 19 0.000
alzheimer s disease DOID:10652 16 0.000
tauopathy DOID:680 16 0.000
cognitive disorder DOID:1561 29 0.000