Homo sapiens

0 known processes

PBK

PDZ binding kinase

(Aliases: Nori-3,SPK,FLJ14385,TOPK,CT84)

PBK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
female gamete generation GO:0007292 2 0.934
regulation of cell cycle GO:0051726 393 0.817
negative regulation of cell cycle GO:0045786 193 0.777
single organism cellular localization GO:1902580 332 0.680
post embryonic development GO:0009791 2 0.671
hard palate development GO:0060022 1 0.608
signal transduction by phosphorylation GO:0023014 297 0.540
Mouse
oogenesis GO:0048477 2 0.531
regulation of mapk cascade GO:0043408 262 0.525
Mouse
oocyte development GO:0048599 1 0.520
positive regulation of phosphorylation GO:0042327 394 0.513
ras protein signal transduction GO:0007265 73 0.502
oocyte differentiation GO:0009994 2 0.490
purine nucleoside catabolic process GO:0006152 398 0.479
mitotic cell cycle GO:0000278 326 0.461
positive regulation of developmental process GO:0051094 314 0.438
negative regulation of phosphate metabolic process GO:0045936 267 0.406
Mouse
locomotory behavior GO:0007626 1 0.390
purine ribonucleoside catabolic process GO:0046130 398 0.384
positive regulation of cellular amine metabolic process GO:0033240 7 0.377
negative regulation of mitotic cell cycle GO:0045930 102 0.377
nucleoside phosphate catabolic process GO:1901292 412 0.374
microtubule cytoskeleton organization GO:0000226 176 0.358
regulation of growth GO:0040008 165 0.352
regulation of cell cycle process GO:0010564 266 0.342
endomembrane system organization GO:0010256 196 0.338
small gtpase mediated signal transduction GO:0007264 78 0.336
regulation of cytoskeleton organization GO:0051493 177 0.334
tube development GO:0035295 125 0.329
tube morphogenesis GO:0035239 95 0.324
regulation of mitotic cell cycle GO:0007346 189 0.322
nucleoside triphosphate metabolic process GO:0009141 422 0.321
ribonucleoside triphosphate catabolic process GO:0009203 391 0.318
ribonucleotide catabolic process GO:0009261 405 0.304
anterior posterior axis specification GO:0009948 2 0.295
establishment of organelle localization GO:0051656 59 0.290
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.288
tripartite regional subdivision GO:0007351 2 0.282
enzyme linked receptor protein signaling pathway GO:0007167 303 0.274
segmentation GO:0035282 4 0.270
positive regulation of cell proliferation GO:0008284 301 0.269
immune response GO:0006955 307 0.263
response to inorganic substance GO:0010035 127 0.257
regulation of protein serine threonine kinase activity GO:0071900 179 0.255
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.253
embryonic morphogenesis GO:0048598 85 0.250
phasic smooth muscle contraction GO:0014821 6 0.249
amine metabolic process GO:0009308 44 0.249
cell development GO:0048468 328 0.245
negative regulation of cellular component organization GO:0051129 235 0.244
epithelium development GO:0060429 227 0.242
regulation of cellular amino acid metabolic process GO:0006521 6 0.237
positive regulation of protein phosphorylation GO:0001934 313 0.237
anterior posterior axis specification embryo GO:0008595 2 0.236
mitotic cell cycle process GO:1903047 286 0.234
anatomical structure formation involved in morphogenesis GO:0048646 284 0.227
microtubule organizing center organization GO:0031023 62 0.225
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.224
Mouse
regulation of protein complex assembly GO:0043254 147 0.223
positive regulation of programmed cell death GO:0043068 249 0.221
kidney morphogenesis GO:0060993 19 0.220
cell fate commitment GO:0045165 27 0.219
negative regulation of cell cycle process GO:0010948 121 0.217
regulation of cellular amine metabolic process GO:0033238 11 0.213
positive regulation of transport GO:0051050 336 0.212
regulation of cellular component size GO:0032535 82 0.211
negative regulation of organelle organization GO:0010639 126 0.208
cytoplasmic transport GO:0016482 379 0.206
growth GO:0040007 202 0.204
positive regulation of transferase activity GO:0051347 227 0.203
negative regulation of cell proliferation GO:0008285 228 0.198
regulation of apoptotic signaling pathway GO:2001233 175 0.195
stress activated protein kinase signaling cascade GO:0031098 94 0.193
Mouse
response to radiation GO:0009314 151 0.192
Mouse
taxis GO:0042330 157 0.190
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.189
negative regulation of apoptotic process GO:0043066 316 0.181
positive regulation of protein kinase activity GO:0045860 190 0.181
ribonucleoside triphosphate metabolic process GO:0009199 412 0.181
regulation of cellular component biogenesis GO:0044087 281 0.179
regulation of cellular ketone metabolic process GO:0010565 50 0.179
purine nucleotide catabolic process GO:0006195 405 0.178
purine ribonucleotide catabolic process GO:0009154 404 0.176
double strand break repair GO:0006302 101 0.173
cation transport GO:0006812 331 0.173
regulation of cellular response to stress GO:0080135 244 0.167
Mouse
response to oxygen containing compound GO:1901700 369 0.167
cellular ketone metabolic process GO:0042180 80 0.167
endothelial cell proliferation GO:0001935 65 0.166
organophosphate catabolic process GO:0046434 430 0.165
ribonucleoside catabolic process GO:0042454 406 0.165
positive regulation of apoptotic process GO:0043065 246 0.164
protein autophosphorylation GO:0046777 123 0.161
regulation of ras protein signal transduction GO:0046578 155 0.158
secretion GO:0046903 254 0.156
microtubule based process GO:0007017 210 0.153
cell fate specification GO:0001708 8 0.152
hematopoietic or lymphoid organ development GO:0048534 186 0.149
nucleotide catabolic process GO:0009166 408 0.145
activation of protein kinase activity GO:0032147 90 0.145
negative regulation of cellular protein metabolic process GO:0032269 353 0.145
Mouse
intracellular protein transport GO:0006886 270 0.139
regulation of dephosphorylation GO:0035303 96 0.139
response to oxidative stress GO:0006979 121 0.138
cell adhesion GO:0007155 325 0.138
negative regulation of hydrolase activity GO:0051346 182 0.136
regulation of kinase activity GO:0043549 314 0.136
dephosphorylation GO:0016311 209 0.135
circulatory system development GO:0072359 262 0.134
regulation of protein polymerization GO:0032271 63 0.132
neuronal action potential GO:0019228 9 0.132
biological adhesion GO:0022610 331 0.130
vesicle mediated transport GO:0016192 371 0.129
regulation of small gtpase mediated signal transduction GO:0051056 156 0.129
nuclear division GO:0000280 128 0.126
nucleoside triphosphate catabolic process GO:0009143 394 0.125
proteasomal protein catabolic process GO:0010498 176 0.124
Mouse
positive regulation of kinase activity GO:0033674 204 0.123
cellular response to oxygen containing compound GO:1901701 276 0.120
cellular component morphogenesis GO:0032989 314 0.120
purine nucleoside triphosphate catabolic process GO:0009146 392 0.120
reproductive process GO:0022414 106 0.119
chromosome segregation GO:0007059 114 0.118
blastoderm segmentation GO:0007350 2 0.117
cellular response to oxidative stress GO:0034599 85 0.117
positive regulation of cytoskeleton organization GO:0051495 83 0.116
g2 m transition of mitotic cell cycle GO:0000086 41 0.116
immune effector process GO:0002252 159 0.113
positive regulation of organelle organization GO:0010638 195 0.109
regulation of response to external stimulus GO:0032101 222 0.109
Mouse
neuromuscular junction development GO:0007528 3 0.108
rho protein signal transduction GO:0007266 26 0.108
negative regulation of catalytic activity GO:0043086 335 0.108
ribonucleoside monophosphate catabolic process GO:0009158 158 0.107
negative regulation of phosphatase activity GO:0010923 61 0.105
purine containing compound catabolic process GO:0072523 411 0.101
regulation of protein transport GO:0051223 213 0.100
regulation of transferase activity GO:0051338 355 0.100
establishment of protein localization to organelle GO:0072594 172 0.096
leukocyte activation GO:0045321 164 0.095
regulation of protein kinase activity GO:0045859 289 0.095
response to transforming growth factor beta GO:0071559 94 0.094
protein oligomerization GO:0051259 173 0.094
mitotic cell cycle phase transition GO:0044772 162 0.093
hemopoiesis GO:0030097 180 0.092
regulation of microtubule based process GO:0032886 74 0.092
ureteric bud morphogenesis GO:0060675 10 0.091
single organism membrane organization GO:0044802 268 0.090
maintenance of location GO:0051235 112 0.090
mapk cascade GO:0000165 288 0.090
Mouse
defense response GO:0006952 315 0.089
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.089
cell activation GO:0001775 213 0.088
regulation of protein localization GO:0032880 296 0.088
g1 s transition of mitotic cell cycle GO:0000082 78 0.088
potassium ion transport GO:0006813 62 0.087
mitotic nuclear division GO:0007067 119 0.086
regulation of cellular protein catabolic process GO:1903362 96 0.085
Mouse
regulation of anatomical structure morphogenesis GO:0022603 286 0.085
positive regulation of hydrolase activity GO:0051345 331 0.084
purine nucleoside monophosphate metabolic process GO:0009126 186 0.084
nucleoside monophosphate catabolic process GO:0009125 159 0.083
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.083
nucleoside catabolic process GO:0009164 408 0.083
single organism cell adhesion GO:0098602 179 0.082
single organism reproductive process GO:0044702 98 0.082
cellular macromolecular complex assembly GO:0034622 324 0.082
immune system development GO:0002520 195 0.082
cellular response to growth factor stimulus GO:0071363 197 0.081
dna repair GO:0006281 198 0.080
regulation of locomotion GO:0040012 329 0.080
response to abiotic stimulus GO:0009628 336 0.079
Mouse
positive regulation of protein localization to nucleus GO:1900182 48 0.077
mating GO:0007618 1 0.076
positive regulation of cell death GO:0010942 263 0.076
regulation of secretion GO:0051046 194 0.073
regulation of phosphatase activity GO:0010921 81 0.073
regulation of lymphocyte activation GO:0051249 103 0.073
negative regulation of phosphorus metabolic process GO:0010563 267 0.072
Mouse
generation of neurons GO:0048699 152 0.072
negative regulation of phosphorylation GO:0042326 174 0.072
Mouse
peptidyl serine phosphorylation GO:0018105 101 0.072
protein localization to organelle GO:0033365 280 0.071
regulation of anatomical structure size GO:0090066 101 0.071
epithelial cell proliferation GO:0050673 128 0.071
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.071
protein localization to nucleus GO:0034504 136 0.071
negative regulation of intracellular signal transduction GO:1902532 183 0.070
Mouse
peptidyl serine modification GO:0018209 106 0.070
muscle contraction GO:0006936 73 0.069
negative regulation of cell death GO:0060548 345 0.069
cell aging GO:0007569 52 0.069
positive regulation of protein polymerization GO:0032273 45 0.068
digestive tract morphogenesis GO:0048546 56 0.068
negative regulation of catabolic process GO:0009895 104 0.066
Mouse
negative regulation of dephosphorylation GO:0035305 63 0.066
positive regulation of meiotic cell cycle GO:0051446 2 0.066
chordate embryonic development GO:0043009 34 0.066
morphogenesis of an epithelium GO:0002009 60 0.066
metal ion transport GO:0030001 272 0.065
positive regulation of cellular component organization GO:0051130 376 0.065
positive regulation of cell differentiation GO:0045597 211 0.065
tissue morphogenesis GO:0048729 96 0.065
response to calcium ion GO:0051592 46 0.065
regulation of cell activation GO:0050865 125 0.064
cell cycle checkpoint GO:0000075 117 0.064
mononuclear cell proliferation GO:0032943 71 0.064
immunological synapse formation GO:0001771 1 0.064
response to growth factor GO:0070848 205 0.063
cytokine production GO:0001816 247 0.062
purine nucleoside monophosphate catabolic process GO:0009128 158 0.062
protein catabolic process GO:0030163 325 0.062
Mouse
regulation of actin filament length GO:0030832 56 0.062
cell cycle phase transition GO:0044770 173 0.061
behavior GO:0007610 112 0.061
circadian behavior GO:0048512 2 0.060
multicellular organismal reproductive process GO:0048609 40 0.060
negative regulation of programmed cell death GO:0043069 321 0.060
neurological system process GO:0050877 163 0.060
purine nucleoside triphosphate metabolic process GO:0009144 412 0.059
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.059
spindle stabilization GO:0043146 4 0.058
muscle system process GO:0003012 81 0.058
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.058
digestive tract development GO:0048565 75 0.057
apoptotic signaling pathway GO:0097190 268 0.057
stress activated mapk cascade GO:0051403 93 0.056
Mouse
adaptive immune response GO:0002250 49 0.055
modification dependent macromolecule catabolic process GO:0043632 212 0.055
Mouse
positive regulation of ras gtpase activity GO:0032320 117 0.055
positive regulation of protein transport GO:0051222 135 0.055
lipid metabolic process GO:0006629 381 0.055
multicellular organism reproduction GO:0032504 42 0.054
regulation of dna metabolic process GO:0051052 153 0.054
response to metal ion GO:0010038 84 0.054
nervous system development GO:0007399 293 0.054
morphogenesis of embryonic epithelium GO:0016331 4 0.054
negative regulation of protein metabolic process GO:0051248 391 0.054
Mouse
protein modification by small protein conjugation GO:0032446 342 0.054
protein homooligomerization GO:0051260 100 0.054
epithelial cell differentiation GO:0030855 141 0.054
cell cycle arrest GO:0007050 71 0.054
lymphocyte activation GO:0046649 133 0.053
establishment of cell polarity GO:0030010 22 0.053
regulation of cytoplasmic transport GO:1903649 149 0.053
protein import GO:0017038 130 0.052
cell cell recognition GO:0009988 4 0.052
regulation of nucleotide catabolic process GO:0030811 205 0.052
regulation of gtp catabolic process GO:0033124 180 0.052
negative regulation of immune system process GO:0002683 136 0.051
response to hydrogen peroxide GO:0042542 40 0.051
cell morphogenesis involved in differentiation GO:0000904 144 0.050
ubiquitin dependent protein catabolic process GO:0006511 206 0.050
Mouse
neurogenesis GO:0022008 169 0.050
centrosome duplication GO:0051298 28 0.050
positive regulation of immune system process GO:0002684 283 0.050
nucleoside monophosphate metabolic process GO:0009123 191 0.049
developmental growth GO:0048589 48 0.049
cell cycle g2 m phase transition GO:0044839 43 0.049
regulation of epithelial cell proliferation GO:0050678 113 0.049
t cell activation GO:0042110 99 0.049
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.049
regulation of protein catabolic process GO:0042176 155 0.049
Mouse
cell fate determination GO:0001709 3 0.049
kidney development GO:0001822 53 0.048
nuclear import GO:0051170 106 0.047
chromatin modification GO:0016568 298 0.047
developmental process involved in reproduction GO:0003006 66 0.047
membrane organization GO:0061024 292 0.047
positive regulation of mapk cascade GO:0043410 190 0.047
cell growth GO:0016049 160 0.047
glycosyl compound catabolic process GO:1901658 413 0.046
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.045
neuroblast proliferation GO:0007405 4 0.045
regulation of microtubule cytoskeleton organization GO:0070507 61 0.045
negative regulation of apoptotic signaling pathway GO:2001234 97 0.045
organelle localization GO:0051640 84 0.045
protein dephosphorylation GO:0006470 81 0.044
cellular response to endogenous stimulus GO:0071495 336 0.044
cellular response to lipid GO:0071396 127 0.044
multicellular organismal aging GO:0010259 3 0.044
neural tube formation GO:0001841 3 0.043
actin filament organization GO:0007015 128 0.043
response to other organism GO:0051707 261 0.043
covalent chromatin modification GO:0016569 254 0.043
epithelial tube morphogenesis GO:0060562 38 0.042
lymphocyte proliferation GO:0046651 70 0.042
actin filament based process GO:0030029 224 0.042
nephron development GO:0072006 30 0.042
regulation of erk1 and erk2 cascade GO:0070372 99 0.042
urogenital system development GO:0001655 65 0.041
regulation of cysteine type endopeptidase activity GO:2000116 127 0.041
cellular component disassembly GO:0022411 92 0.041
receptor mediated endocytosis GO:0006898 84 0.041
response to biotic stimulus GO:0009607 276 0.041
purine ribonucleoside metabolic process GO:0046128 437 0.041
erbb signaling pathway GO:0038127 44 0.041
dna packaging GO:0006323 77 0.040
cellular macromolecule catabolic process GO:0044265 380 0.040
Mouse
spindle checkpoint GO:0031577 26 0.040
regulation of organelle assembly GO:1902115 40 0.040
cellular protein complex assembly GO:0043623 188 0.040
positive regulation of cellular component biogenesis GO:0044089 158 0.039
cell junction organization GO:0034330 79 0.039
response to external biotic stimulus GO:0043207 261 0.039
mitotic cell cycle checkpoint GO:0007093 68 0.039
leukocyte apoptotic process GO:0071887 31 0.039
organelle assembly GO:0070925 176 0.039
actin cytoskeleton organization GO:0030036 207 0.038
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.038
cell substrate adhesion GO:0031589 132 0.038
positive regulation of nucleotide catabolic process GO:0030813 185 0.038
multi organism reproductive process GO:0044703 54 0.038
guanosine containing compound catabolic process GO:1901069 239 0.038
cellular amine metabolic process GO:0044106 41 0.038
actin polymerization or depolymerization GO:0008154 56 0.038
atp catabolic process GO:0006200 157 0.038
centrosome organization GO:0051297 58 0.038
action potential GO:0001508 34 0.037
system process GO:0003008 349 0.037
regulation of gtpase activity GO:0043087 180 0.037
positive regulation of peptidase activity GO:0010952 88 0.037
negative regulation of cell growth GO:0030308 83 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
regulation of endopeptidase activity GO:0052548 170 0.036
regulation of cell differentiation GO:0045595 393 0.036
positive regulation of nucleoside metabolic process GO:0045979 186 0.036
determination of adult lifespan GO:0008340 2 0.036
single organismal cell cell adhesion GO:0016337 148 0.036
positive regulation of nucleotide metabolic process GO:0045981 230 0.035
positive regulation of cellular component movement GO:0051272 181 0.035
lens development in camera type eye GO:0002088 2 0.035
mitotic spindle elongation GO:0000022 4 0.035
positive regulation of protein complex assembly GO:0031334 86 0.035
regulation of intracellular transport GO:0032386 195 0.035
maintenance of protein location GO:0045185 57 0.034
negative regulation of protein complex disassembly GO:0043242 20 0.034
regulation of mitotic cell cycle phase transition GO:1901990 118 0.034
male gamete generation GO:0048232 22 0.034
regulation of cell adhesion GO:0030155 166 0.033
regulation of cell motility GO:2000145 299 0.033
cellular amino acid metabolic process GO:0006520 116 0.033
protein ubiquitination GO:0016567 314 0.033
regulation of binding GO:0051098 111 0.032
positive regulation of cell development GO:0010720 92 0.032
regulation of proteolysis GO:0030162 293 0.032
Mouse
regulation of cellular component movement GO:0051270 334 0.032
chemical homeostasis GO:0048878 306 0.032
regulation of protein targeting GO:1903533 91 0.032
regulation of cell cycle phase transition GO:1901987 126 0.031
regulation of developmental growth GO:0048638 30 0.031
neuron differentiation GO:0030182 138 0.031
embryo development GO:0009790 123 0.031
adult locomotory behavior GO:0008344 1 0.031
regulation of actin filament based process GO:0032970 141 0.031
response to reactive oxygen species GO:0000302 61 0.031
regulation of peptidase activity GO:0052547 180 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
regulation of leukocyte proliferation GO:0070663 67 0.031
positive regulation of intracellular protein transport GO:0090316 76 0.031
stem cell division GO:0017145 2 0.031
protein secretion GO:0009306 98 0.031
regulation of protein maturation GO:1903317 150 0.031
Mouse
single organism nuclear import GO:1902593 104 0.031
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.030
lymphocyte mediated immunity GO:0002449 48 0.030
primary neural tube formation GO:0014020 3 0.030
reproduction GO:0000003 63 0.030
adherens junction organization GO:0034332 36 0.030
regulation of cell morphogenesis GO:0022604 153 0.029
response to lipid GO:0033993 206 0.029
regulation of membrane potential GO:0042391 95 0.029
hindbrain development GO:0030902 3 0.029
myeloid cell differentiation GO:0030099 117 0.029
embryo development ending in birth or egg hatching GO:0009792 34 0.029
gtp metabolic process GO:0046039 239 0.029
reproductive system development GO:0061458 56 0.029
protein import into nucleus GO:0006606 104 0.029
mesonephric epithelium development GO:0072163 14 0.029
erk1 and erk2 cascade GO:0070371 104 0.029
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.028
monovalent inorganic cation transport GO:0015672 128 0.028
regulation of establishment of protein localization GO:0070201 242 0.028
positive regulation of intracellular transport GO:0032388 104 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.028
Mouse
cellular response to radiation GO:0071478 65 0.027
Mouse
protein targeting GO:0006605 187 0.027
dna dependent dna replication GO:0006261 44 0.027
mesonephric tubule development GO:0072164 14 0.027
cellular protein catabolic process GO:0044257 261 0.027
Mouse
cellular lipid metabolic process GO:0044255 303 0.027
regulation of intracellular protein transport GO:0033157 123 0.027
branching involved in ureteric bud morphogenesis GO:0001658 9 0.027
chromatin organization GO:0006325 351 0.027
photoreceptor cell differentiation GO:0046530 2 0.027
cytokine production involved in immune response GO:0002367 27 0.027
regulation of cellular response to growth factor stimulus GO:0090287 76 0.026
regulation of t cell activation GO:0050863 77 0.026
production of molecular mediator of immune response GO:0002440 37 0.026
epidermal growth factor receptor signaling pathway GO:0007173 39 0.026
renal system development GO:0072001 63 0.026
secretion by cell GO:0032940 226 0.026
response to nutrient levels GO:0031667 81 0.026
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.026
regulation of hormone levels GO:0010817 125 0.026
chromatin assembly or disassembly GO:0006333 78 0.025
dna replication GO:0006260 116 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.025
Mouse
sexual reproduction GO:0019953 37 0.025
regulation of cell development GO:0060284 161 0.025
regulation of protein depolymerization GO:1901879 22 0.025
gtp catabolic process GO:0006184 237 0.025
regulation of protein localization to nucleus GO:1900180 85 0.025
reproductive structure development GO:0048608 55 0.025
response to extracellular stimulus GO:0009991 85 0.025
macromolecular complex disassembly GO:0032984 60 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.024
protein maturation GO:0051604 233 0.024
Mouse
spindle elongation GO:0051231 4 0.024
protein acetylation GO:0006473 116 0.024
cell cycle g1 s phase transition GO:0044843 80 0.024
mesonephros development GO:0001823 17 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
protein acylation GO:0043543 138 0.024
mitochondrion organization GO:0007005 156 0.024
muscle tissue development GO:0060537 62 0.024
cell type specific apoptotic process GO:0097285 125 0.024
endocytosis GO:0006897 159 0.024
cellular response to external stimulus GO:0071496 111 0.024
negative regulation of cell cycle phase transition GO:1901988 89 0.023
organ morphogenesis GO:0009887 147 0.023
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.023
leukocyte proliferation GO:0070661 74 0.023
organic acid biosynthetic process GO:0016053 97 0.023
spermatid development GO:0007286 4 0.023
cellular response to biotic stimulus GO:0071216 71 0.023
regulation of meiotic cell cycle GO:0051445 4 0.023
gamete generation GO:0007276 25 0.023
regulation of nervous system development GO:0051960 88 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.023
positive regulation of endopeptidase activity GO:0010950 84 0.023
establishment of protein localization to membrane GO:0090150 121 0.023
transmembrane transport GO:0055085 399 0.023
histone modification GO:0016570 251 0.023
cardiovascular system development GO:0072358 262 0.023
regulation of protein processing GO:0070613 150 0.022
Mouse
cell cell signaling GO:0007267 155 0.022
brain development GO:0007420 97 0.022
t cell mediated immunity GO:0002456 25 0.022
positive regulation of catabolic process GO:0009896 310 0.022
innate immune response GO:0045087 178 0.022
cellular response to metal ion GO:0071248 43 0.022
protein tetramerization GO:0051262 47 0.022
microtubule polymerization or depolymerization GO:0031109 37 0.022
neuron development GO:0048666 113 0.022
regulation of ion transport GO:0043269 189 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
positive regulation of gtpase activity GO:0043547 166 0.022
cellular response to reactive oxygen species GO:0034614 50 0.022
regulation of actin polymerization or depolymerization GO:0008064 56 0.022
regulation of multi organism process GO:0043900 157 0.021
response to organic cyclic compound GO:0014070 204 0.021
cellular calcium ion homeostasis GO:0006874 117 0.021
positive regulation of nervous system development GO:0051962 54 0.021
regulation of dna replication GO:0006275 68 0.021
positive regulation of dna metabolic process GO:0051054 73 0.021
rna processing GO:0006396 255 0.021
organelle fission GO:0048285 149 0.021
regulation of jak stat cascade GO:0046425 44 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
g protein coupled receptor signaling pathway GO:0007186 207 0.021
actin filament polymerization GO:0030041 45 0.021
response to hormone GO:0009725 175 0.020
oxidation reduction process GO:0055114 396 0.020
jak stat cascade GO:0007259 46 0.020
regulation of protein ubiquitination GO:0031396 95 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
cell morphogenesis GO:0000902 296 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
rhythmic behavior GO:0007622 2 0.020
regulation of protein import into nucleus GO:0042306 78 0.020
oocyte maturation GO:0001556 1 0.020
regulation of actin cytoskeleton organization GO:0032956 116 0.020
cellular response to nutrient levels GO:0031669 69 0.020
regulation of rho protein signal transduction GO:0035023 79 0.020
nuclear migration GO:0007097 1 0.020
protein processing GO:0016485 226 0.019
Mouse
embryonic epithelial tube formation GO:0001838 4 0.019
embryonic placenta development GO:0001892 1 0.019
positive regulation of secretion GO:0051047 116 0.019
peptidyl tyrosine phosphorylation GO:0018108 170 0.019
negative regulation of lymphocyte activation GO:0051250 24 0.019
negative regulation of developmental process GO:0051093 247 0.019

PBK disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.050
disease of cellular proliferation DOID:14566 174 0.022