Homo sapiens

57 known processes

PCBP2

poly(rC) binding protein 2

(Aliases: MGC110998,HNRPE2,hnRNP-E2)

PCBP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 175 0.956
mrna processing GO:0006397 133 0.935
rna processing GO:0006396 255 0.934
rna splicing GO:0008380 131 0.896
post embryonic development GO:0009791 2 0.803
determination of adult lifespan GO:0008340 2 0.747
negative regulation of mrna catabolic process GO:1902373 4 0.709
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 8 0.708
regulation of rna splicing GO:0043484 62 0.688
regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000622 3 0.654
mrna destabilization GO:0061157 1 0.635
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.573
cellular macromolecule catabolic process GO:0044265 380 0.565
multicellular organismal aging GO:0010259 3 0.513
negative regulation of rna catabolic process GO:1902369 4 0.481
regulation of meiosis GO:0040020 3 0.436
negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000623 3 0.365
chemotaxis GO:0006935 157 0.299
negative regulation of mrna metabolic process GO:1903312 15 0.257
vesicle mediated transport GO:0016192 371 0.236
mrna catabolic process GO:0006402 56 0.232
translation GO:0006412 132 0.228
nuclear transcribed mrna catabolic process GO:0000956 48 0.222
cellular macromolecular complex assembly GO:0034622 324 0.216
regulation of meiotic cell cycle GO:0051445 4 0.211
mrna splicing via spliceosome GO:0000398 89 0.206
regulation of mrna processing GO:0050684 48 0.206
nuclear transcribed mrna catabolic process no go decay GO:0070966 2 0.203
modification dependent macromolecule catabolic process GO:0043632 212 0.186
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.184
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.180
protein catabolic process GO:0030163 325 0.178
regulation of mrna metabolic process GO:1903311 53 0.176
regulation of multi organism process GO:0043900 157 0.162
immune effector process GO:0002252 159 0.160
rna destabilization GO:0050779 1 0.157
3 utr mediated mrna destabilization GO:0061158 1 0.155
defense response to virus GO:0051607 71 0.146
positive regulation of mrna 3 end processing GO:0031442 12 0.126
rna splicing via transesterification reactions GO:0000375 90 0.125
plasma lipoprotein particle clearance GO:0034381 16 0.124
receptor mediated endocytosis GO:0006898 84 0.122
rna catabolic process GO:0006401 71 0.121
behavior GO:0007610 112 0.114
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 0.109
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.105
defense response GO:0006952 315 0.101
negative regulation of cellular protein metabolic process GO:0032269 353 0.100
positive regulation of translation GO:0045727 35 0.098
translational initiation GO:0006413 48 0.093
long chain fatty acid metabolic process GO:0001676 30 0.093
regulation of mrna catabolic process GO:0061013 13 0.090
posttranscriptional regulation of gene expression GO:0010608 213 0.090
negative regulation of protein metabolic process GO:0051248 391 0.089
regulation of mrna splicing via spliceosome GO:0048024 32 0.087
organelle assembly GO:0070925 176 0.086
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.085
regulation of mrna 3 end processing GO:0031440 12 0.085
nervous system development GO:0007399 293 0.081
regulation of response to external stimulus GO:0032101 222 0.079
memory GO:0007613 3 0.076
digestive tract morphogenesis GO:0048546 56 0.073
reproduction GO:0000003 63 0.072
regulation of translational initiation GO:0006446 24 0.071
defense response to other organism GO:0098542 129 0.071
ribonucleoprotein complex biogenesis GO:0022613 116 0.070
ncrna catabolic process GO:0034661 14 0.065
aging GO:0007568 66 0.064
anterior posterior axis specification GO:0009948 2 0.063
tripartite regional subdivision GO:0007351 2 0.061
modification dependent protein catabolic process GO:0019941 209 0.060
oocyte differentiation GO:0009994 2 0.058
oogenesis GO:0048477 2 0.057
response to external biotic stimulus GO:0043207 261 0.052
positive regulation of organelle organization GO:0010638 195 0.052
lens development in camera type eye GO:0002088 2 0.052
regulation of synaptic plasticity GO:0048167 3 0.051
negative regulation of defense response GO:0031348 47 0.049
cellular component morphogenesis GO:0032989 314 0.049
cellular protein catabolic process GO:0044257 261 0.047
oocyte development GO:0048599 1 0.047
neurogenesis GO:0022008 169 0.047
anterior posterior axis specification embryo GO:0008595 2 0.046
neuron differentiation GO:0030182 138 0.046
regulation of response to biotic stimulus GO:0002831 55 0.044
cytoplasmic mrna processing body assembly GO:0033962 10 0.043
endocytosis GO:0006897 159 0.043
embryo development GO:0009790 123 0.042
regulation of defense response to virus GO:0050688 33 0.041
calcium ion homeostasis GO:0055074 122 0.041
positive regulation of mrna metabolic process GO:1903313 19 0.040
rna 3 end processing GO:0031123 35 0.040
ubiquitin dependent protein catabolic process GO:0006511 206 0.039
cellular divalent inorganic cation homeostasis GO:0072503 128 0.039
lipid metabolic process GO:0006629 381 0.039
female gamete generation GO:0007292 2 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.038
cellular lipid metabolic process GO:0044255 303 0.038
negative regulation of immune system process GO:0002683 136 0.038
negative regulation of catabolic process GO:0009895 104 0.037
response to biotic stimulus GO:0009607 276 0.037
chromosome segregation GO:0007059 114 0.037
positive regulation of cell cycle GO:0045787 140 0.037
ion homeostasis GO:0050801 230 0.036
regulation of proteolysis GO:0030162 293 0.036
chromatin organization GO:0006325 351 0.035
long term synaptic potentiation GO:0060291 1 0.034
positive regulation of cytoplasmic mrna processing body assembly GO:0010606 4 0.034
cell morphogenesis GO:0000902 296 0.034
positive regulation of cellular catabolic process GO:0031331 284 0.034
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.034
regulation of translation GO:0006417 89 0.033
positive regulation of catabolic process GO:0009896 310 0.033
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.033
purine nucleoside triphosphate catabolic process GO:0009146 392 0.033
glial cell migration GO:0008347 4 0.032
negative regulation of defense response to virus GO:0050687 10 0.032
regulation of low density lipoprotein particle receptor biosynthetic process GO:0045714 4 0.031
monocarboxylic acid metabolic process GO:0032787 185 0.031
anatomical structure formation involved in morphogenesis GO:0048646 284 0.031
meiosis i GO:0007127 4 0.031
positive regulation of synaptic transmission GO:0050806 4 0.030
regulation of organelle assembly GO:1902115 40 0.030
proteasomal protein catabolic process GO:0010498 176 0.030
negative regulation of response to external stimulus GO:0032102 83 0.029
regulation of peptidase activity GO:0052547 180 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.029
organelle fission GO:0048285 149 0.029
circulatory system development GO:0072359 262 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.028
spermatid differentiation GO:0048515 4 0.027
carboxylic acid biosynthetic process GO:0046394 97 0.027
positive regulation of mrna catabolic process GO:0061014 10 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
cell fate determination GO:0001709 3 0.026
response to other organism GO:0051707 261 0.026
transmission of nerve impulse GO:0019226 11 0.026
ncrna metabolic process GO:0034660 108 0.026
oxidation reduction process GO:0055114 396 0.026
regulation of cell cycle process GO:0010564 266 0.025
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.025
reproductive process GO:0022414 106 0.025
single organism reproductive process GO:0044702 98 0.025
organic acid biosynthetic process GO:0016053 97 0.025
cellular chemical homeostasis GO:0055082 180 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
protein maturation GO:0051604 233 0.025
intrinsic apoptotic signaling pathway GO:0097193 127 0.024
reproductive structure development GO:0048608 55 0.024
cellular response to histamine GO:0071420 3 0.024
regulation of nuclear division GO:0051783 65 0.024
cell division GO:0051301 168 0.024
rna interference GO:0016246 4 0.024
neurological system process GO:0050877 163 0.024
single organism behavior GO:0044708 28 0.023
protein processing GO:0016485 226 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
cell morphogenesis involved in differentiation GO:0000904 144 0.023
low density lipoprotein particle receptor biosynthetic process GO:0045713 5 0.022
rrna metabolic process GO:0016072 40 0.022
fatty acid metabolic process GO:0006631 115 0.022
positive regulation of cell cycle process GO:0090068 106 0.022
tissue homeostasis GO:0001894 63 0.022
receptor metabolic process GO:0043112 81 0.022
fatty acid biosynthetic process GO:0006633 46 0.021
protein methylation GO:0006479 74 0.021
biological adhesion GO:0022610 331 0.021
cation homeostasis GO:0055080 189 0.021
blastoderm segmentation GO:0007350 2 0.021
axon development GO:0061564 34 0.021
response to virus GO:0009615 126 0.020
metal ion transport GO:0030001 272 0.020
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.020
actin mediated cell contraction GO:0070252 12 0.020
cellular calcium ion homeostasis GO:0006874 117 0.020
cation transport GO:0006812 331 0.020
methylation GO:0032259 106 0.020
ribonucleoprotein complex subunit organization GO:0071826 81 0.020
positive regulation of meiotic cell cycle GO:0051446 2 0.019
hemopoiesis GO:0030097 180 0.019
regulation of cell maturation GO:1903429 3 0.019
regulation of transferase activity GO:0051338 355 0.019
melanin metabolic process GO:0006582 1 0.019
mrna 3 end processing GO:0031124 24 0.019
digestive tract development GO:0048565 75 0.019
cell projection morphogenesis GO:0048858 129 0.019
cellular component disassembly GO:0022411 92 0.019
intracellular protein transport GO:0006886 270 0.019
adult behavior GO:0030534 18 0.018
formation of primary germ layer GO:0001704 42 0.018
low density lipoprotein particle clearance GO:0034383 8 0.018
protein targeting GO:0006605 187 0.018
cell growth GO:0016049 160 0.018
endoderm formation GO:0001706 33 0.018
ribonucleoprotein complex assembly GO:0022618 78 0.018
regulation of cell growth GO:0001558 135 0.017
sex determination GO:0007530 3 0.017
sequestering of metal ion GO:0051238 24 0.017
organophosphate catabolic process GO:0046434 430 0.017
somatic muscle development GO:0007525 1 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
embryonic hemopoiesis GO:0035162 4 0.017
positive regulation of ossification GO:0045778 32 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
regulation of cell cycle GO:0051726 393 0.017
cell part morphogenesis GO:0032990 137 0.016
long chain fatty acid biosynthetic process GO:0042759 4 0.016
regulation of ossification GO:0030278 58 0.016
rho protein signal transduction GO:0007266 26 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
monocarboxylic acid biosynthetic process GO:0072330 67 0.016
regulation of response to dna damage stimulus GO:2001020 94 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
nucleosome organization GO:0034728 66 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
negative regulation of cell cycle GO:0045786 193 0.016
axonogenesis GO:0007409 31 0.016
lens morphogenesis in camera type eye GO:0002089 2 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
actin filament based process GO:0030029 224 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
cation transmembrane transport GO:0098655 238 0.015
myeloid cell differentiation GO:0030099 117 0.015
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.015
dna conformation change GO:0071103 113 0.015
locomotory behavior GO:0007626 1 0.015
purine containing compound catabolic process GO:0072523 411 0.015
protein ubiquitination GO:0016567 314 0.015
negative regulation of developmental process GO:0051093 247 0.015
macromolecule methylation GO:0043414 97 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.015
mitotic cell cycle GO:0000278 326 0.015
negative regulation of cellular catabolic process GO:0031330 83 0.015
cellular ion homeostasis GO:0006873 168 0.014
chemical homeostasis GO:0048878 306 0.014
cellular homeostasis GO:0019725 196 0.014
intracellular mrna localization GO:0008298 1 0.014
negative regulation of protein modification process GO:0031400 200 0.014
response to axon injury GO:0048678 1 0.014
negative regulation of gene silencing by rna GO:0060967 3 0.014
system process GO:0003008 349 0.014
cellular cation homeostasis GO:0030003 163 0.014
protein dna complex subunit organization GO:0071824 80 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
actin filament based movement GO:0030048 17 0.014
regulation of ion transmembrane transporter activity GO:0032412 72 0.014
regulation of cell differentiation GO:0045595 393 0.014
neuromuscular junction development GO:0007528 3 0.014
lung alveolus development GO:0048286 4 0.014
chromatin assembly GO:0031497 61 0.014
motor neuron axon guidance GO:0008045 2 0.014
positive regulation of organelle assembly GO:1902117 17 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
nucleotide catabolic process GO:0009166 408 0.013
metal ion homeostasis GO:0055065 169 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
pituitary gland development GO:0021983 2 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
regulation of leukocyte differentiation GO:1902105 61 0.013
regulation of cellular response to stress GO:0080135 244 0.013
establishment of nucleus localization GO:0040023 1 0.013
cardiovascular system development GO:0072358 262 0.013
macromolecular complex disassembly GO:0032984 60 0.013
mitotic cell cycle process GO:1903047 286 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
positive regulation of immune system process GO:0002684 283 0.013
rna export from nucleus GO:0006405 33 0.013
cell projection organization GO:0030030 252 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
positive regulation of translational initiation GO:0045948 7 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
heart development GO:0007507 95 0.013
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
nuclear transcribed mrna poly a tail shortening GO:0000289 8 0.012
secretion GO:0046903 254 0.012
regulation of endocytosis GO:0030100 72 0.012
anatomical structure homeostasis GO:0060249 100 0.012
regulation of axon guidance GO:1902667 3 0.012
response to bacterium GO:0009617 144 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
spliceosomal complex assembly GO:0000245 17 0.012
regulation of feeding behavior GO:0060259 3 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
immune response GO:0006955 307 0.012
nuclear division GO:0000280 128 0.012
regulation of muscle cell differentiation GO:0051147 31 0.012
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.012
axon regeneration GO:0031103 1 0.012
positive regulation of endopeptidase activity GO:0010950 84 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.012
regulation of gtpase activity GO:0043087 180 0.012
peptidyl proline modification GO:0018208 15 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
dna templated transcription termination GO:0006353 3 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
cellular response to growth factor stimulus GO:0071363 197 0.011
regulation of oocyte development GO:0060281 1 0.011
apoptotic signaling pathway GO:0097190 268 0.011
microtubule based process GO:0007017 210 0.011
tube morphogenesis GO:0035239 95 0.011
cellular protein complex disassembly GO:0043624 36 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
protein autophosphorylation GO:0046777 123 0.011
spermatid development GO:0007286 4 0.011
alternative mrna splicing via spliceosome GO:0000380 27 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
carbohydrate metabolic process GO:0005975 207 0.011
regulation of plasma lipoprotein particle levels GO:0097006 32 0.011
smoothened signaling pathway GO:0007224 14 0.011
maintenance of location in cell GO:0051651 62 0.011
sensory perception of pain GO:0019233 4 0.011
dna packaging GO:0006323 77 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
cellular amine metabolic process GO:0044106 41 0.011
positive regulation of transport GO:0051050 336 0.011
intracellular receptor signaling pathway GO:0030522 104 0.011
embryonic camera type eye development GO:0031076 2 0.011
meiotic chromosome segregation GO:0045132 4 0.011
small molecule biosynthetic process GO:0044283 157 0.011
muscle cell fate commitment GO:0042693 4 0.011
cellular response to ammonium ion GO:0071242 4 0.011
actomyosin structure organization GO:0031032 59 0.011
positive regulation of hormone biosynthetic process GO:0046886 4 0.011
calcium ion transmembrane transport GO:0070588 76 0.010
lipid biosynthetic process GO:0008610 177 0.010
embryonic morphogenesis GO:0048598 85 0.010
regulation of kinase activity GO:0043549 314 0.010
regulation of growth GO:0040008 165 0.010
somitogenesis GO:0001756 2 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
response to endoplasmic reticulum stress GO:0034976 49 0.010
regulation of heart morphogenesis GO:2000826 4 0.010
positive regulation of cell division GO:0051781 59 0.010
divalent inorganic cation homeostasis GO:0072507 136 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.010
positive regulation of protein phosphorylation GO:0001934 313 0.010
detection of stimulus GO:0051606 85 0.010
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.010
positive regulation of mrna processing GO:0050685 17 0.010
taxis GO:0042330 157 0.010
erk1 and erk2 cascade GO:0070371 104 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010

PCBP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.114
nervous system disease DOID:863 431 0.114
sensory system disease DOID:0050155 203 0.068
disease of cellular proliferation DOID:14566 174 0.068
neurodegenerative disease DOID:1289 102 0.048
eye and adnexa disease DOID:1492 150 0.043
eye disease DOID:5614 149 0.043
immune system disease DOID:2914 155 0.037
retinal disease DOID:5679 118 0.032
retinal degeneration DOID:8466 89 0.032
musculoskeletal system disease DOID:17 223 0.020
cancer DOID:162 167 0.019
organ system cancer DOID:0050686 164 0.019
disease of metabolism DOID:0014667 295 0.018
auditory system disease DOID:2742 53 0.017
cardiovascular system disease DOID:1287 106 0.017
retinitis pigmentosa DOID:10584 51 0.016
heart disease DOID:114 68 0.015
nonsyndromic deafness DOID:0050563 50 0.013
myopathy DOID:423 104 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
cardiomyopathy DOID:0050700 50 0.012
intrinsic cardiomyopathy DOID:0060036 50 0.012
connective tissue disease DOID:65 109 0.011
anemia DOID:2355 55 0.011
hematopoietic system disease DOID:74 100 0.011
inherited metabolic disorder DOID:655 242 0.010