|
|
histone monoubiquitination
|
GO:0010390 |
20 |
1.000
|
Human |
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.992
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.989
|
Human |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.981
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.979
|
Human |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.943
|
Human Mouse Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.940
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.932
|
Fly |
|
|
gene silencing
|
GO:0016458 |
49 |
0.921
|
Fly |
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.897
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.839
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.839
|
|
|
|
histone h2a monoubiquitination
|
GO:0035518 |
11 |
0.838
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.837
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.809
|
Mouse Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.809
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.809
|
|
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
0.801
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.793
|
Fly |
|
|
wound healing
|
GO:0042060 |
115 |
0.774
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.740
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.709
|
Fly |
|
|
neuron development
|
GO:0048666 |
113 |
0.685
|
Fly |
|
|
response to wounding
|
GO:0009611 |
168 |
0.625
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.622
|
Fly |
|
|
histone modification
|
GO:0016570 |
251 |
0.615
|
Human Mouse |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.524
|
Mouse |
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.512
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.509
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.491
|
Human Mouse Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.435
|
Fly |
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.422
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.408
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.405
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.402
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.372
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.372
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.372
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.371
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.337
|
Human Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.328
|
Mouse |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.320
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.309
|
Mouse |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.302
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.301
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.285
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.271
|
Mouse |
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.268
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
7 |
0.268
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.262
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.245
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.241
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.230
|
Mouse |
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.226
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.210
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.206
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.186
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.183
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.180
|
Fly |
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.180
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.179
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.175
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.162
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.155
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.146
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.143
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.136
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.134
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.132
|
Mouse |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.130
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.129
|
Human |
|
|
response to ketone
|
GO:1901654 |
19 |
0.128
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.128
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.123
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.121
|
Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.120
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.119
|
|
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
31 |
0.119
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.119
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.117
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.115
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.113
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.113
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.112
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.111
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.109
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.108
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.107
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.106
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.102
|
Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.101
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.100
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.098
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.098
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.097
|
|
|
|
ovarian follicle development
|
GO:0001541 |
5 |
0.097
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.095
|
|
|
|
monoubiquitinated protein deubiquitination
|
GO:0035520 |
6 |
0.095
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.089
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.089
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.085
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.083
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.081
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.078
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.077
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.075
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.075
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.072
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.072
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.072
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.072
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.072
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.071
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.070
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.070
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.070
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.069
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.068
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.067
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.067
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.067
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
1 |
0.066
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.066
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.066
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.064
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.063
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.063
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.062
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.061
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.061
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.059
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.058
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.058
|
|
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.058
|
|
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
89 |
0.058
|
|
|
|
response to sterol
|
GO:0036314 |
14 |
0.057
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.056
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.055
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.053
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.052
|
Fly |
|
|
sebaceous gland development
|
GO:0048733 |
1 |
0.052
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.052
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
5 |
0.051
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.050
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.050
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.050
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
90 |
0.050
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.049
|
Mouse |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.048
|
Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.048
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.048
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.048
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.047
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.047
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.046
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.046
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.046
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.046
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.046
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.046
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.045
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.045
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.045
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.044
|
Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.044
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.044
|
|
|
|
neuron maturation
|
GO:0042551 |
5 |
0.043
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.043
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.043
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.043
|
|
|
|
protein localization to cell surface
|
GO:0034394 |
28 |
0.042
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.041
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.041
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.040
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.040
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.039
|
Mouse |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.039
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.039
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.039
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.039
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.039
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.039
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.038
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.038
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.038
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.037
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.037
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.037
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.036
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.036
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.036
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.036
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.036
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.035
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.035
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.035
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.034
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.034
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.034
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.034
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.034
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.034
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.034
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.033
|
Mouse |
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.033
|
Fly |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.033
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.032
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.032
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.032
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.032
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.031
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.031
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.031
|
|
|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
12 |
0.031
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.031
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.031
|
Mouse |
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
9 |
0.030
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.030
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.030
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.030
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.030
|
Mouse |
|
|
taxis
|
GO:0042330 |
157 |
0.030
|
Fly |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.030
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.029
|
Fly |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.029
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.029
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.029
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.029
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.029
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.028
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.028
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.028
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.028
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.028
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.028
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.028
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.027
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.027
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.027
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
9 |
0.027
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.027
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.027
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.027
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.027
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.027
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.027
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.026
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
89 |
0.026
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.026
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.026
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.026
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.026
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.026
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.026
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.026
|
Fly |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.026
|
|
|
|
ovulation cycle process
|
GO:0022602 |
9 |
0.026
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.026
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.026
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.025
|
|
|
|
growth
|
GO:0040007 |
202 |
0.025
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.025
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.025
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.025
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.025
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.025
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.024
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.024
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.024
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.024
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.024
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.024
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.024
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.024
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.023
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.023
|
Mouse |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.023
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.023
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.023
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.023
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.023
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.023
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.023
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.023
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.023
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.022
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.022
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.022
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.022
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.022
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.022
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.022
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.022
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.022
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.021
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.021
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.021
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.021
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.021
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.021
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.021
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.021
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.020
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.020
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.020
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.020
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.020
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.020
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.020
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.020
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.020
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.020
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.020
|
|
|
|
response to uv a
|
GO:0070141 |
6 |
0.020
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.020
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.020
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.020
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.020
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
1 |
0.019
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.019
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.019
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.019
|
|
|
|
spliceosomal tri snrnp complex assembly
|
GO:0000244 |
7 |
0.019
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.019
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.019
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.019
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.019
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.019
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.019
|
Mouse |
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.019
|
|
|
|
system process
|
GO:0003008 |
349 |
0.019
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.019
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.018
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.018
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.018
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.018
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.018
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.018
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.018
|
|
|
|
positive regulation of ligase activity
|
GO:0051351 |
19 |
0.018
|
Human |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.018
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.018
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.018
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.018
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.018
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.018
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.017
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
9 |
0.017
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.017
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.017
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.017
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.017
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.017
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.017
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.017
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.017
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.017
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.017
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.017
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.017
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.017
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.017
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.017
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.017
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.017
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.017
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.016
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.016
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.016
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.016
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.016
|
Fly |
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.016
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.016
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.016
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.016
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.016
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.016
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.016
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.016
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.016
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.016
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.016
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.016
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.016
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.016
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.016
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.016
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.016
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.016
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.015
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.015
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.015
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.015
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.015
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.015
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.015
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.015
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.015
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.015
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.015
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.015
|
Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.015
|
|
|
|
establishment or maintenance of monopolar cell polarity
|
GO:0061339 |
1 |
0.015
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.015
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.015
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.015
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.015
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.015
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.015
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.015
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.015
|
Fly |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.014
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.014
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.014
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.014
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.014
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.014
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.014
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.014
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.014
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.014
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.014
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.014
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.014
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.014
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.014
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.014
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.014
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.014
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.014
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.014
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.014
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.014
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.014
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.014
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.014
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.014
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.014
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.014
|
Fly |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.014
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.014
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.014
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.014
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
31 |
0.014
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.013
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.013
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.013
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.013
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.013
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
10 |
0.013
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.013
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.013
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.013
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.013
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.013
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.013
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.013
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.013
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.013
|
|
|
|
neuron projection guidance
|
GO:0097485 |
12 |
0.013
|
Fly |
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.013
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.013
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.013
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.013
|
|
|
|
head development
|
GO:0060322 |
108 |
0.013
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.013
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.013
|
Mouse |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.012
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.012
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.012
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.012
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.012
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.012
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.012
|
|
|
|
axon extension involved in axon guidance
|
GO:0048846 |
5 |
0.012
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.012
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.012
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.012
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
19 |
0.012
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.012
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.012
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.012
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.012
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.012
|
|
