Homo sapiens

0 known processes

PDE6D

phosphodiesterase 6D, cGMP-specific, rod, delta

(Aliases: PDED)

PDE6D biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
intraciliary transport GO:0042073 7 1.000
endoplasmic reticulum tubular network organization GO:0071786 8 1.000
endoplasmic reticulum organization GO:0007029 20 0.992
organophosphate catabolic process GO:0046434 430 0.942
Mouse
guanosine containing compound metabolic process GO:1901068 244 0.933
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.887
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.885
Mouse
gtp metabolic process GO:0046039 239 0.885
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.877
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.854
Mouse
guanosine containing compound catabolic process GO:1901069 239 0.847
Mouse
glycosyl compound catabolic process GO:1901658 413 0.834
Mouse
nucleotide catabolic process GO:0009166 408 0.818
Mouse
ribonucleotide catabolic process GO:0009261 405 0.807
Mouse
ribonucleoside catabolic process GO:0042454 406 0.790
Mouse
establishment of protein localization to endoplasmic reticulum membrane GO:0097051 3 0.787
regulation of protein polymerization GO:0032271 63 0.752
gtp catabolic process GO:0006184 237 0.747
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.734
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.730
Mouse
purine nucleoside catabolic process GO:0006152 398 0.721
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.630
Mouse
cilium morphogenesis GO:0060271 75 0.628
nucleoside phosphate catabolic process GO:1901292 412 0.605
Mouse
cilium organization GO:0044782 68 0.586
positive regulation of tor signaling GO:0032008 11 0.579
post golgi vesicle mediated transport GO:0006892 36 0.568
cytokinesis GO:0000910 96 0.543
cellular component morphogenesis GO:0032989 314 0.528
purine nucleotide catabolic process GO:0006195 405 0.505
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.499
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.460
cell development GO:0048468 328 0.451
purine ribonucleoside catabolic process GO:0046130 398 0.449
Mouse
golgi vesicle transport GO:0048193 80 0.419
endomembrane system organization GO:0010256 196 0.415
positive regulation of protein polymerization GO:0032273 45 0.403
protein targeting to peroxisome GO:0006625 15 0.387
organelle inheritance GO:0048308 2 0.380
regulation of microtubule polymerization GO:0031113 12 0.376
cell morphogenesis GO:0000902 296 0.372
positive regulation of cytoskeleton organization GO:0051495 83 0.345
photoreceptor cell differentiation GO:0046530 2 0.329
protein polymerization GO:0051258 71 0.316
cilium assembly GO:0042384 63 0.303
cell division GO:0051301 168 0.294
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.288
nucleoside catabolic process GO:0009164 408 0.269
Mouse
positive regulation of cellular component biogenesis GO:0044089 158 0.269
nervous system development GO:0007399 293 0.239
purine nucleoside triphosphate catabolic process GO:0009146 392 0.230
Mouse
microtubule based process GO:0007017 210 0.225
cell projection organization GO:0030030 252 0.221
endosomal transport GO:0016197 129 0.215
purine ribonucleotide catabolic process GO:0009154 404 0.206
Mouse
mitochondrion distribution GO:0048311 3 0.205
kidney development GO:0001822 53 0.201
positive regulation of cellular amine metabolic process GO:0033240 7 0.200
neuron differentiation GO:0030182 138 0.198
regulation of cellular amine metabolic process GO:0033238 11 0.196
neuromuscular junction development GO:0007528 3 0.188
cellular amine metabolic process GO:0044106 41 0.187
cell part morphogenesis GO:0032990 137 0.184
regulation of kinase activity GO:0043549 314 0.179
urogenital system development GO:0001655 65 0.169
regulation of nucleotide catabolic process GO:0030811 205 0.168
Mouse
neurogenesis GO:0022008 169 0.159
positive regulation of protein complex assembly GO:0031334 86 0.155
peroxisomal transport GO:0043574 15 0.155
cellular macromolecular complex assembly GO:0034622 324 0.155
smoothened signaling pathway GO:0007224 14 0.149
positive regulation of cellular component organization GO:0051130 376 0.144
establishment of protein localization to peroxisome GO:0072663 15 0.142
golgi organization GO:0007030 38 0.139
generation of neurons GO:0048699 152 0.139
protein localization to peroxisome GO:0072662 15 0.132
microtubule polymerization GO:0046785 18 0.128
vesicle mediated transport GO:0016192 371 0.127
regulation of vesicle mediated transport GO:0060627 130 0.126
purine containing compound catabolic process GO:0072523 411 0.123
Mouse
intracellular protein transmembrane transport GO:0065002 24 0.123
regulation of protein complex assembly GO:0043254 147 0.122
biological adhesion GO:0022610 331 0.121
positive regulation of nucleotide metabolic process GO:0045981 230 0.120
locomotory behavior GO:0007626 1 0.118
cellular protein complex assembly GO:0043623 188 0.115
cation transport GO:0006812 331 0.113
regulation of purine nucleotide catabolic process GO:0033121 205 0.113
Mouse
neuron development GO:0048666 113 0.109
maintenance of protein location in nucleus GO:0051457 12 0.107
cytoskeleton dependent intracellular transport GO:0030705 21 0.106
positive regulation of kinase activity GO:0033674 204 0.105
cell adhesion GO:0007155 325 0.105
regulation of purine nucleotide metabolic process GO:1900542 264 0.103
Mouse
acetylcholine transport GO:0015870 1 0.102
cytoplasmic transport GO:0016482 379 0.097
regulation of cytoskeleton organization GO:0051493 177 0.096
regulation of nucleoside metabolic process GO:0009118 209 0.092
Mouse
cell projection morphogenesis GO:0048858 129 0.090
microtubule polymerization or depolymerization GO:0031109 37 0.090
positive regulation of transport GO:0051050 336 0.090
establishment of protein localization to organelle GO:0072594 172 0.089
regulation of gtpase activity GO:0043087 180 0.089
regulation of gtp catabolic process GO:0033124 180 0.086
Mouse
amine metabolic process GO:0009308 44 0.085
single organism membrane fusion GO:0044801 37 0.084
neuron projection development GO:0031175 106 0.082
regulation of cellular ketone metabolic process GO:0010565 50 0.081
transmembrane transport GO:0055085 399 0.080
protein folding GO:0006457 38 0.079
regulation of anatomical structure size GO:0090066 101 0.079
intracellular protein transmembrane import GO:0044743 23 0.076
negative regulation of nucleotide catabolic process GO:0030812 16 0.075
establishment of protein localization to membrane GO:0090150 121 0.074
nitrogen compound transport GO:0071705 191 0.074
microtubule cytoskeleton organization GO:0000226 176 0.073
regulation of cellular component size GO:0032535 82 0.072
negative regulation of catabolic process GO:0009895 104 0.070
secretion GO:0046903 254 0.066
reactive oxygen species metabolic process GO:0072593 75 0.066
regulation of actin polymerization or depolymerization GO:0008064 56 0.063
single organism membrane organization GO:0044802 268 0.062
taxis GO:0042330 157 0.061
vesicle organization GO:0016050 62 0.060
maintenance of location in cell GO:0051651 62 0.059
regulation of anatomical structure morphogenesis GO:0022603 286 0.059
maintenance of protein location in cell GO:0032507 56 0.058
chemotaxis GO:0006935 157 0.058
regulation of transferase activity GO:0051338 355 0.058
actin filament polymerization GO:0030041 45 0.058
renal system development GO:0072001 63 0.057
regulation of actin filament polymerization GO:0030833 50 0.057
positive regulation of organelle organization GO:0010638 195 0.056
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.056
cell projection assembly GO:0030031 126 0.056
regulation of microtubule cytoskeleton organization GO:0070507 61 0.055
organelle assembly GO:0070925 176 0.054
positive regulation of catabolic process GO:0009896 310 0.054
regulation of reactive oxygen species metabolic process GO:2000377 41 0.054
positive regulation of gtp catabolic process GO:0033126 166 0.053
regulation of actin filament based process GO:0032970 141 0.052
angiogenesis GO:0001525 147 0.052
ribonucleoprotein complex biogenesis GO:0022613 116 0.051
positive regulation of nucleotide catabolic process GO:0030813 185 0.051
microtubule based movement GO:0007018 32 0.050
epithelium development GO:0060429 227 0.049
protein localization to membrane GO:0072657 160 0.049
protein localization to organelle GO:0033365 280 0.048
exocytosis GO:0006887 71 0.048
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.047
vesicle docking involved in exocytosis GO:0006904 3 0.047
cellular ketone metabolic process GO:0042180 80 0.046
microtubule organizing center organization GO:0031023 62 0.046
cytokinetic process GO:0032506 12 0.046
positive regulation of phosphorylation GO:0042327 394 0.046
protein transmembrane transport GO:0071806 25 0.045
intracellular protein transport GO:0006886 270 0.045
regulation of translation GO:0006417 89 0.045
positive regulation of transferase activity GO:0051347 227 0.043
protein import GO:0017038 130 0.042
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.041
negative regulation of hydrolase activity GO:0051346 182 0.040
positive regulation of protein phosphorylation GO:0001934 313 0.040
protein localization to nucleus GO:0034504 136 0.039
plasma membrane organization GO:0007009 115 0.039
regulation of secretion GO:0051046 194 0.039
regulation of ribosome biogenesis GO:0090069 1 0.039
regulation of cell morphogenesis GO:0022604 153 0.038
golgi inheritance GO:0048313 2 0.038
regulation of autophagy GO:0010506 52 0.038
regulation of protein kinase activity GO:0045859 289 0.038
small gtpase mediated signal transduction GO:0007264 78 0.038
regulation of cell cycle process GO:0010564 266 0.037
positive regulation of protein kinase activity GO:0045860 190 0.037
vesicle fusion GO:0006906 17 0.036
protein targeting to membrane GO:0006612 42 0.036
membrane organization GO:0061024 292 0.035
membrane fusion GO:0061025 43 0.035
cellular component assembly involved in morphogenesis GO:0010927 73 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.033
positive regulation of actin filament polymerization GO:0030838 38 0.033
protein ubiquitination GO:0016567 314 0.033
protein localization to endoplasmic reticulum GO:0070972 19 0.032
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.032
ubiquitin dependent protein catabolic process GO:0006511 206 0.032
golgi localization GO:0051645 4 0.032
compound eye development GO:0048749 1 0.032
cellular response to nitrogen compound GO:1901699 144 0.032
regulation of nucleotide metabolic process GO:0006140 269 0.031
Mouse
regulation of cell shape GO:0008360 48 0.031
translation GO:0006412 132 0.031
positive regulation of nucleoside metabolic process GO:0045979 186 0.031
positive regulation of secretion GO:0051047 116 0.031
circulatory system development GO:0072359 262 0.031
posttranscriptional regulation of gene expression GO:0010608 213 0.030
cell junction assembly GO:0034329 67 0.030
actin polymerization or depolymerization GO:0008154 56 0.029
post embryonic development GO:0009791 2 0.029
establishment of protein localization to plasma membrane GO:0090002 68 0.029
chromatin organization GO:0006325 351 0.029
mitochondrion organization GO:0007005 156 0.029
cellular response to oxygen containing compound GO:1901701 276 0.029
tissue migration GO:0090130 119 0.029
single organism cellular localization GO:1902580 332 0.029
maintenance of protein localization in organelle GO:0072595 15 0.028
protein modification by small protein conjugation GO:0032446 342 0.028
vacuole organization GO:0007033 44 0.028
determination of adult lifespan GO:0008340 2 0.028
rho protein signal transduction GO:0007266 26 0.027
antigen processing and presentation GO:0019882 33 0.027
positive regulation of secretion by cell GO:1903532 108 0.027
adult locomotory behavior GO:0008344 1 0.026
microtubule based transport GO:0010970 21 0.026
negative regulation of cellular catabolic process GO:0031330 83 0.026
centrosome organization GO:0051297 58 0.025
chromatin modification GO:0016568 298 0.025
maintenance of location GO:0051235 112 0.025
positive regulation of rho protein signal transduction GO:0035025 4 0.025
epithelial cell differentiation GO:0030855 141 0.025
actin filament based movement GO:0030048 17 0.025
positive regulation of exocytosis GO:0045921 35 0.025
negative regulation of nucleotide metabolic process GO:0045980 29 0.025
peptidyl tyrosine phosphorylation GO:0018108 170 0.025
regulation of endocytosis GO:0030100 72 0.024
response to oxygen containing compound GO:1901700 369 0.024
negative regulation of nucleoside metabolic process GO:0045978 18 0.024
protein autophosphorylation GO:0046777 123 0.024
mitotic cell cycle process GO:1903047 286 0.024
cellular amino acid metabolic process GO:0006520 116 0.023
protein targeting GO:0006605 187 0.023
cellular response to endogenous stimulus GO:0071495 336 0.023
protein kinase a signaling GO:0010737 9 0.023
positive regulation of translation GO:0045727 35 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
mitotic cell cycle GO:0000278 326 0.022
system process GO:0003008 349 0.022
epithelial cell development GO:0002064 34 0.021
mitochondrion localization GO:0051646 10 0.021
modification dependent macromolecule catabolic process GO:0043632 212 0.021
single organism reproductive process GO:0044702 98 0.021
endocytosis GO:0006897 159 0.021
regulation of mapk cascade GO:0043408 262 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
regulation of clathrin mediated endocytosis GO:2000369 4 0.020
cell cell adhesion mediated by cadherin GO:0044331 4 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
covalent chromatin modification GO:0016569 254 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
histone modification GO:0016570 251 0.019
spermatid differentiation GO:0048515 4 0.019
maintenance of protein location GO:0045185 57 0.019
dendritic spine morphogenesis GO:0060997 3 0.019
multicellular organismal aging GO:0010259 3 0.018
protein localization to cell leading edge GO:1902463 1 0.018
regulation of secretion by cell GO:1903530 177 0.018
actin mediated cell contraction GO:0070252 12 0.018
cellular response to peptide hormone stimulus GO:0071375 56 0.018
lipid metabolic process GO:0006629 381 0.018
autophagy GO:0006914 88 0.018
actin cytoskeleton organization GO:0030036 207 0.018
regulation of protein catabolic process GO:0042176 155 0.018
regulated secretory pathway GO:0045055 20 0.017
endothelial cell migration GO:0043542 86 0.017
response to starvation GO:0042594 59 0.017
centrosome cycle GO:0007098 32 0.017
regulation of protein localization GO:0032880 296 0.017
positive regulation of cell death GO:0010942 263 0.017
positive regulation of cell size GO:0045793 3 0.017
negative regulation of organelle organization GO:0010639 126 0.017
cell cell junction assembly GO:0007043 25 0.017
macroautophagy GO:0016236 39 0.017
negative regulation of cytoskeleton organization GO:0051494 45 0.017
cellular response to dna damage stimulus GO:0006974 379 0.016
g1 s transition of mitotic cell cycle GO:0000082 78 0.016
endothelial cell chemotaxis GO:0035767 13 0.016
response to hormone GO:0009725 175 0.016
golgi to plasma membrane transport GO:0006893 21 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
apoptotic signaling pathway GO:0097190 268 0.016
receptor mediated endocytosis GO:0006898 84 0.016
actin filament organization GO:0007015 128 0.016
positive regulation of cell projection organization GO:0031346 64 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.015
response to peptide hormone GO:0043434 61 0.015
regulation of protein transport GO:0051223 213 0.015
regulation of cytokinesis GO:0032465 45 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
response to nitrogen compound GO:1901698 184 0.015
regeneration GO:0031099 4 0.015
carbohydrate metabolic process GO:0005975 207 0.015
response to organonitrogen compound GO:0010243 156 0.015
regulation of cell adhesion GO:0030155 166 0.015
cell chemotaxis GO:0060326 112 0.015
regulation of proteolysis GO:0030162 293 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
cell morphogenesis involved in differentiation GO:0000904 144 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
cellular response to hormone stimulus GO:0032870 125 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
response to organic cyclic compound GO:0014070 204 0.015
secretion by cell GO:0032940 226 0.015
acetate ester transport GO:1901374 1 0.014
multicellular organismal response to stress GO:0033555 1 0.014
response to radiation GO:0009314 151 0.014
organelle localization GO:0051640 84 0.014
regulation of cellular protein catabolic process GO:1903362 96 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.014
regulation of protein ubiquitination GO:0031396 95 0.014
memory GO:0007613 3 0.014
negative regulation of protein complex assembly GO:0031333 43 0.014
regulation of intracellular transport GO:0032386 195 0.013
meiosis i GO:0007127 4 0.013
hair follicle morphogenesis GO:0031069 2 0.013
regulation of microtubule based process GO:0032886 74 0.013
protein maturation GO:0051604 233 0.013
peroxisome organization GO:0007031 28 0.013
response to abiotic stimulus GO:0009628 336 0.013
response to insulin GO:0032868 45 0.013
actin filament based process GO:0030029 224 0.013
dephosphorylation GO:0016311 209 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
regulation of cell cycle GO:0051726 393 0.013
nuclear import GO:0051170 106 0.013
neurotransmitter secretion GO:0007269 4 0.013
oogenesis GO:0048477 2 0.013
protein processing GO:0016485 226 0.013
apical junction assembly GO:0043297 19 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
cortical actin cytoskeleton organization GO:0030866 9 0.013
rna interference GO:0016246 4 0.013
male gonad development GO:0008584 23 0.012
regulation of cell projection organization GO:0031344 107 0.012
negative regulation of cellular protein metabolic process GO:0032269 353 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
regulation of actin filament length GO:0030832 56 0.012
protein acylation GO:0043543 138 0.012
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.012
axon development GO:0061564 34 0.012
collateral sprouting GO:0048668 2 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
nuclear transport GO:0051169 179 0.012
protein acetylation GO:0006473 116 0.012
cell growth GO:0016049 160 0.012
protein catabolic process GO:0030163 325 0.012
regulation of protein maturation GO:1903317 150 0.012
spermatid development GO:0007286 4 0.012
nerve development GO:0021675 4 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
centriole replication GO:0007099 13 0.012
epithelial cell migration GO:0010631 119 0.012
blood vessel morphogenesis GO:0048514 162 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
dna repair GO:0006281 198 0.011
vasculature development GO:0001944 181 0.011
regulation of protein processing GO:0070613 150 0.011
negative regulation of growth GO:0045926 97 0.011
cellular response to inorganic substance GO:0071241 45 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
establishment of protein localization to endoplasmic reticulum GO:0072599 11 0.011
peptidyl lysine acetylation GO:0018394 101 0.011
melanin metabolic process GO:0006582 1 0.011
positive regulation of myotube differentiation GO:0010831 3 0.011
sequestering of calcium ion GO:0051208 17 0.011
protein import into peroxisome membrane GO:0045046 5 0.011
motor neuron axon guidance GO:0008045 2 0.011
mapk cascade GO:0000165 288 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
peripheral nervous system development GO:0007422 2 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
cellular response to metal ion GO:0071248 43 0.011
optic nerve development GO:0021554 2 0.011
axonogenesis GO:0007409 31 0.011
regulation of growth GO:0040008 165 0.010
negative regulation of cell size GO:0045792 3 0.010
regulation of cellular response to stress GO:0080135 244 0.010
interspecies interaction between organisms GO:0044419 156 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
positive regulation of microtubule polymerization or depolymerization GO:0031112 8 0.010
positive regulation of regulated secretory pathway GO:1903307 8 0.010
purine nucleotide biosynthetic process GO:0006164 84 0.010
multi organism cellular process GO:0044764 156 0.010
cellular response to peptide GO:1901653 59 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
activation of protein kinase activity GO:0032147 90 0.010
regulation of cell projection assembly GO:0060491 47 0.010

PDE6D disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.091
eye and adnexa disease DOID:1492 150 0.091
nervous system disease DOID:863 431 0.091
retinal disease DOID:5679 118 0.048
retinal degeneration DOID:8466 89 0.048
eye disease DOID:5614 149 0.048
retinitis pigmentosa DOID:10584 51 0.026
immune system disease DOID:2914 155 0.021
urinary system disease DOID:18 40 0.019
kidney disease DOID:557 36 0.018
musculoskeletal system disease DOID:17 223 0.018
central nervous system disease DOID:331 186 0.012
neurodegenerative disease DOID:1289 102 0.012
muscular disease DOID:0080000 114 0.010
connective tissue disease DOID:65 109 0.010