Homo sapiens

154 known processes

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

(Aliases: PDGFR,CD140B,PDGFR1,JTK12)

PDGFRB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vegf activated platelet derived growth factor receptor signaling pathway GO:0038086 3 1.000
regulation of metanephric mesenchymal cell migration GO:2000589 2 1.000
Mouse
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway GO:0038091 3 1.000
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 1.000
Human Mouse
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 1.000
Human Mouse
angiogenesis involved in wound healing GO:0060055 4 1.000
regulation of smooth muscle cell migration GO:0014910 15 1.000
positive regulation of map kinase activity GO:0043406 80 1.000
Human Mouse
vascular endothelial growth factor receptor 1 signaling pathway GO:0036323 1 1.000
Human
vascular wound healing GO:0061042 4 1.000
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 2 1.000
Mouse
cell chemotaxis GO:0060326 112 1.000
positive regulation of endothelial cell migration GO:0010595 39 1.000
Human
positive regulation of mapk cascade GO:0043410 190 0.999
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.999
muscle cell migration GO:0014812 19 0.999
platelet derived growth factor receptor alpha signaling pathway GO:0035790 1 0.999
Human
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.999
glycerolipid metabolic process GO:0046486 107 0.999
activation of protein kinase activity GO:0032147 90 0.999
Human
branching involved in salivary gland morphogenesis GO:0060445 1 0.999
regulation of epithelial cell migration GO:0010632 93 0.998
Human
positive regulation of metanephric mesenchymal cell migration GO:2000591 2 0.998
Mouse
regulation of smooth muscle cell proliferation GO:0048660 28 0.998
regulation of stress activated mapk cascade GO:0032872 84 0.998
Human
regulation of cell migration GO:0030334 289 0.998
regulation of locomotion GO:0040012 329 0.998
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 9 0.998
Human
circulatory system development GO:0072359 262 0.998
Human Mouse
positive regulation of peptidyl tyrosine autophosphorylation GO:1900086 1 0.998
regulation of chemotaxis GO:0050920 74 0.998
Human Mouse
regulation of mapk cascade GO:0043408 262 0.997
cellular response to nitrogen compound GO:1901699 144 0.997
Fly
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.997
Human
regulation of glomerulus development GO:0090192 3 0.997
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.997
positive regulation of epithelial cell proliferation GO:0050679 65 0.997
Human
positive regulation of vascular wound healing GO:0035470 1 0.997
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.996
Human
negative regulation of phosphatidylinositol biosynthetic process GO:0010512 2 0.996
endothelial cell migration GO:0043542 86 0.996
Human
cell migration involved in kidney development GO:0035787 2 0.996
Mouse Rat
peptidyl tyrosine modification GO:0018212 170 0.996
calcium mediated signaling using intracellular calcium source GO:0035584 7 0.996
Human
cellular response to endogenous stimulus GO:0071495 336 0.996
regulation of mast cell chemotaxis GO:0060753 4 0.996
positive regulation of smooth muscle cell migration GO:0014911 6 0.995
regulation of erk1 and erk2 cascade GO:0070372 99 0.995
positive regulation of locomotion GO:0040017 186 0.995
regulation of endothelial cell migration GO:0010594 67 0.995
Human
mast cell chemotaxis GO:0002551 5 0.995
Human
cyclic nucleotide metabolic process GO:0009187 82 0.994
positive regulation of histone deacetylase activity GO:1901727 3 0.994
regulation of cell motility GO:2000145 299 0.994
regulation of map kinase activity GO:0043405 108 0.994
Human Mouse
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.994
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.994
negative regulation of platelet activation GO:0010544 7 0.993
Human
metanephric mesenchymal cell migration GO:0035789 2 0.993
Mouse Rat
anatomical structure formation involved in morphogenesis GO:0048646 284 0.993
Human Mouse
response to wounding GO:0009611 168 0.993
Human Rat
regulation of vascular wound healing GO:0061043 2 0.993
positive regulation of mast cell chemotaxis GO:0060754 4 0.993
negative regulation of wound healing GO:0061045 25 0.993
Human
positive regulation of dna replication GO:0045740 35 0.993
Human
regulation of reactive oxygen species metabolic process GO:2000377 41 0.992
Mouse
smooth muscle cell migration GO:0014909 18 0.992
positive regulation of focal adhesion assembly GO:0051894 11 0.992
Human
blood vessel morphogenesis GO:0048514 162 0.992
Human Mouse
regulation of coagulation GO:0050818 44 0.992
Human
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.991
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.990
Human Mouse
taxis GO:0042330 157 0.990
positive regulation of jnk cascade GO:0046330 52 0.990
Human
blood vessel development GO:0001568 172 0.989
Human Mouse
cell substrate adhesion GO:0031589 132 0.988
Human
regulation of cellular amine metabolic process GO:0033238 11 0.988
basophil chemotaxis GO:0002575 1 0.988
leukocyte chemotaxis GO:0030595 76 0.987
Human
activation of mapk activity GO:0000187 45 0.987
Human
reactive oxygen species metabolic process GO:0072593 75 0.987
Mouse
glomerular mesangial cell proliferation GO:0072110 3 0.987
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.986
positive regulation of behavior GO:0048520 60 0.986
Human Mouse
focal adhesion assembly GO:0048041 30 0.985
Human
positive regulation of cell adhesion GO:0045785 84 0.985
Human
digestive system development GO:0055123 75 0.985
Fly
epithelial cell migration GO:0010631 119 0.984
Human Fly
mapk cascade GO:0000165 288 0.984
positive regulation of kinase activity GO:0033674 204 0.984
epithelium migration GO:0090132 119 0.984
Human Fly
monocyte chemotaxis GO:0002548 20 0.983
Human
tube development GO:0035295 125 0.983
Fly
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.983
positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway GO:0038033 4 0.983
positive regulation of leukocyte chemotaxis GO:0002690 38 0.982
positive regulation of lipid metabolic process GO:0045834 50 0.982
angiogenesis GO:0001525 147 0.982
Human Mouse
actin filament based process GO:0030029 224 0.982
Human Mouse Fly
biological adhesion GO:0022610 331 0.982
Human
cellular lipid metabolic process GO:0044255 303 0.981
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 12 0.981
Human
regulation of cellular component biogenesis GO:0044087 281 0.981
Human
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.981
positive regulation of dna metabolic process GO:0051054 73 0.980
Human Mouse
cellular ketone metabolic process GO:0042180 80 0.980
negative regulation of hemostasis GO:1900047 22 0.980
Human
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.979
Human
metanephric glomerulus development GO:0072224 2 0.979
Mouse Rat
sprouting angiogenesis GO:0002040 29 0.979
positive regulation of cell proliferation GO:0008284 301 0.978
positive regulation of cell substrate adhesion GO:0010811 37 0.978
Human
positive regulation of glomerular mesangial cell proliferation GO:0072126 1 0.977
vasculature development GO:0001944 181 0.976
Human Mouse
salivary gland morphogenesis GO:0007435 4 0.973
Fly
regulation of focal adhesion assembly GO:0051893 20 0.971
Human
glomerulus development GO:0032835 15 0.971
Mouse Rat
negative regulation of coagulation GO:0050819 24 0.971
Human
regulation of leukocyte chemotaxis GO:0002688 46 0.970
platelet derived growth factor receptor signaling pathway GO:0048008 14 0.970
metanephric glomerulus vasculature development GO:0072239 1 0.969
Mouse
protein autophosphorylation GO:0046777 123 0.969
cell migration involved in metanephros development GO:0035788 2 0.968
Mouse Rat
amine metabolic process GO:0009308 44 0.968
positive regulation of cellular amine metabolic process GO:0033240 7 0.967
response to abiotic stimulus GO:0009628 336 0.967
Rat
regulation of kinase activity GO:0043549 314 0.967
positive regulation of response to external stimulus GO:0032103 88 0.966
Human Mouse
organ morphogenesis GO:0009887 147 0.964
Mouse Rat Fly
rho protein signal transduction GO:0007266 26 0.963
mast cell cytokine production GO:0032762 1 0.962
Human
regulation of cellular component movement GO:0051270 334 0.961
positive regulation of stress activated mapk cascade GO:0032874 60 0.961
Human
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.961
Human
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 11 0.961
Human
regulation of cell substrate junction assembly GO:0090109 20 0.961
Human
tissue migration GO:0090130 119 0.960
Human Fly
actin cytoskeleton organization GO:0030036 207 0.960
Human Mouse Fly
mast cell degranulation GO:0043303 4 0.960
Human
jnk cascade GO:0007254 80 0.959
Human
stress activated mapk cascade GO:0051403 93 0.958
Human
regulation of glomerular mesangial cell proliferation GO:0072124 3 0.958
stress activated protein kinase signaling cascade GO:0031098 94 0.956
Human
cell substrate adherens junction assembly GO:0007045 30 0.956
Human
positive regulation of protein kinase b signaling GO:0051897 42 0.956
regulation of endothelial cell proliferation GO:0001936 56 0.956
Human
positive regulation of endothelial cell proliferation GO:0001938 37 0.956
Human
digestive tract development GO:0048565 75 0.955
Fly
positive regulation of protein kinase activity GO:0045860 190 0.954
Human Mouse
regulation of hemostasis GO:1900046 42 0.953
Human
response to organonitrogen compound GO:0010243 156 0.951
Fly
positive regulation of fibroblast proliferation GO:0048146 21 0.950
Human
response to oxygen containing compound GO:1901700 369 0.949
Rat Fly
second messenger mediated signaling GO:0019932 78 0.948
Human
tissue morphogenesis GO:0048729 96 0.948
Fly
positive regulation of phosphorylation GO:0042327 394 0.947
regulation of positive chemotaxis GO:0050926 14 0.947
Human
regulation of cell adhesion GO:0030155 166 0.945
Human
cellular amine metabolic process GO:0044106 41 0.944
heart development GO:0007507 95 0.944
Mouse
cell morphogenesis GO:0000902 296 0.943
Human Fly
negative regulation of blood coagulation GO:0030195 22 0.942
Human
response to growth factor GO:0070848 205 0.941
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.941
Human Mouse
muscle cell proliferation GO:0033002 35 0.941
regulation of cell matrix adhesion GO:0001952 42 0.941
Human
regulation of peptidyl tyrosine autophosphorylation GO:1900084 1 0.941
regulation of leukocyte migration GO:0002685 63 0.940
peptidyl tyrosine phosphorylation GO:0018108 170 0.940
hemostasis GO:0007599 76 0.939
Human
receptor internalization GO:0031623 43 0.939
cellular response to organonitrogen compound GO:0071417 124 0.938
Fly
platelet activation GO:0030168 44 0.938
Human
gastrulation GO:0007369 51 0.936
positive regulation of adherens junction organization GO:1903393 12 0.936
Human
regulation of jnk cascade GO:0046328 73 0.935
Human
cellular response to oxygen containing compound GO:1901701 276 0.935
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.935
cell adhesion GO:0007155 325 0.934
Human
digestive tract morphogenesis GO:0048546 56 0.932
Fly
cell activation GO:0001775 213 0.930
Human
cardiovascular system development GO:0072358 262 0.929
Human Mouse
regulation of cell junction assembly GO:1901888 29 0.928
Human
regulation of cellular response to stress GO:0080135 244 0.927
Human
blood coagulation GO:0007596 76 0.927
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.924
Human Fly
positive regulation of chemotaxis GO:0050921 57 0.924
Human Mouse
smooth muscle cell proliferation GO:0048659 28 0.921
regulation of epithelial cell proliferation GO:0050678 113 0.920
Human
positive chemotaxis GO:0050918 33 0.920
Human
protein kinase c signaling GO:0070528 17 0.920
Human
signal transduction by phosphorylation GO:0023014 297 0.920
glycerophospholipid metabolic process GO:0006650 84 0.919
positive regulation of protein phosphorylation GO:0001934 313 0.917
Human Mouse
morphogenesis of an epithelium GO:0002009 60 0.916
Fly
epithelium development GO:0060429 227 0.914
Fly
regulation of transferase activity GO:0051338 355 0.914
regulation of angiogenesis GO:0045765 92 0.911
Human
regulation of lipid kinase activity GO:0043550 19 0.909
chemotaxis GO:0006935 157 0.909
regulation of protein kinase c signaling GO:0090036 8 0.908
Human
gland morphogenesis GO:0022612 8 0.907
Fly
regulation of ion transmembrane transport GO:0034765 132 0.907
Mouse
regulation of cell proliferation involved in kidney development GO:1901722 3 0.905
fc receptor signaling pathway GO:0038093 2 0.904
Human
positive regulation of cellular component movement GO:0051272 181 0.902
cellular response to peptide GO:1901653 59 0.899
Fly
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.897
Human Mouse
positive regulation of cell migration GO:0030335 172 0.892
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.891
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.890
regulation of cellular amino acid metabolic process GO:0006521 6 0.888
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.887
Human
regulation of lipid metabolic process GO:0019216 96 0.887
regulation of cell substrate adhesion GO:0010810 68 0.887
Human
positive regulation of jak stat cascade GO:0046427 35 0.885
Human
positive regulation of p38mapk cascade GO:1900745 8 0.884
regulation of mitosis GO:0007088 63 0.883
Mouse
regulation of anatomical structure morphogenesis GO:0022603 286 0.882
Human Fly
erk1 and erk2 cascade GO:0070371 104 0.879
negative regulation of locomotion GO:0040013 118 0.875
vascular endothelial growth factor signaling pathway GO:0038084 15 0.872
positive regulation of developmental process GO:0051094 314 0.870
Human Mouse
myeloid cell differentiation GO:0030099 117 0.867
regulation of phosphatidylinositol biosynthetic process GO:0010511 5 0.864
response to peptide GO:1901652 65 0.863
Fly
cell proliferation involved in kidney development GO:0072111 3 0.862
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.860
Human
regulation of adherens junction organization GO:1903391 21 0.860
Human
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.856
Human Mouse
wound healing GO:0042060 115 0.855
Human Rat
regulation of cellular response to growth factor stimulus GO:0090287 76 0.851
Human
granulocyte migration GO:0097530 40 0.848
mucopolysaccharide metabolic process GO:1903510 27 0.848
cell matrix adhesion GO:0007160 85 0.844
Human
tube morphogenesis GO:0035239 95 0.843
Fly
positive regulation of cell division GO:0051781 59 0.838
Mouse
positive regulation of leukocyte migration GO:0002687 46 0.837
cellular component morphogenesis GO:0032989 314 0.834
Human Mouse Fly
negative regulation of cell migration GO:0030336 102 0.833
cytosolic calcium ion homeostasis GO:0051480 89 0.828
Human
regulation of blood coagulation GO:0030193 42 0.825
Human
cell junction organization GO:0034330 79 0.823
Human
regulation of cell migration involved in sprouting angiogenesis GO:0090049 9 0.820
humoral immune response GO:0006959 49 0.818
Fly
ras protein signal transduction GO:0007265 73 0.816
cell migration involved in sprouting angiogenesis GO:0002042 19 0.815
cellular response to peptide hormone stimulus GO:0071375 56 0.811
Fly
cellular response to insulin stimulus GO:0032869 41 0.809
Fly
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 0.801
Human
negative regulation of gastrulation GO:2000542 4 0.800
myeloid leukocyte migration GO:0097529 62 0.800
Human
response to stem cell factor GO:0036215 1 0.798
Human
dna replication GO:0006260 116 0.796
Human
regulation of cgmp metabolic process GO:0030823 9 0.795
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.795
Mouse
positive regulation of phosphoprotein phosphatase activity GO:0032516 9 0.795
negative regulation of developmental process GO:0051093 247 0.794
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 2 0.792
Mouse
regulation of protein kinase activity GO:0045859 289 0.791
Human Mouse
epithelial cell proliferation GO:0050673 128 0.789
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.788
Human
urogenital system development GO:0001655 65 0.785
Mouse Rat Fly
negative regulation of programmed cell death GO:0043069 321 0.784
Human Rat Fly
regulation of histone deacetylase activity GO:1901725 3 0.784
response to nitrogen compound GO:1901698 184 0.782
Fly
connective tissue development GO:0061448 39 0.781
Mouse
muscle structure development GO:0061061 98 0.780
Mouse
positive regulation of cell motility GO:2000147 177 0.777
positive regulation of epithelial cell migration GO:0010634 55 0.770
Human
activation of protein kinase b activity GO:0032148 14 0.764
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.764
Human
phosphatidylinositol mediated signaling GO:0048015 55 0.760
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.759
Human
positive regulation of calcium ion transport GO:0051928 51 0.755
Mouse
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.751
response to macrophage colony stimulating factor GO:0036005 4 0.751
Human
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.746
cellular amino acid metabolic process GO:0006520 116 0.744
immune response GO:0006955 307 0.743
Human Fly
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.740
behavior GO:0007610 112 0.740
Human Mouse
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.740
kit signaling pathway GO:0038109 1 0.740
Human
phosphatidylinositol metabolic process GO:0046488 53 0.737
cell projection organization GO:0030030 252 0.735
Fly
positive regulation of protein localization to early endosome GO:1902966 2 0.735
lipid metabolic process GO:0006629 381 0.734
granulocyte chemotaxis GO:0071621 37 0.734
calcium ion import GO:0070509 23 0.732
Mouse
negative regulation of cell proliferation GO:0008285 228 0.727
response to peptide hormone GO:0043434 61 0.726
Fly
osteoblast differentiation GO:0001649 92 0.725
blood vessel endothelial cell migration GO:0043534 42 0.724
ameboidal type cell migration GO:0001667 135 0.724
Human Fly
lipid biosynthetic process GO:0008610 177 0.719
regulation of behavior GO:0050795 82 0.717
Human Mouse
positive regulation of protein kinase c signaling GO:0090037 5 0.716
Human
negative regulation of lipid metabolic process GO:0045833 38 0.714
positive regulation of immune system process GO:0002684 283 0.708
gland development GO:0048732 48 0.706
Mouse Fly
negative regulation of response to external stimulus GO:0032102 83 0.704
Human
negative regulation of apoptotic process GO:0043066 316 0.703
Human Rat Fly
positive regulation of cell junction assembly GO:1901890 11 0.703
Human
regulation of neuron apoptotic process GO:0043523 35 0.701
response to fibroblast growth factor GO:0071774 39 0.698
regulation of mesenchymal stem cell differentiation GO:2000739 6 0.698
Human
regulation of immune response GO:0050776 201 0.698
Human
lung alveolus development GO:0048286 4 0.696
regulation of receptor internalization GO:0002090 15 0.695
blood circulation GO:0008015 113 0.691
negative regulation of cell death GO:0060548 345 0.690
Human Rat Fly
regulation of vasculature development GO:1901342 97 0.684
Human
regulation of endothelial cell apoptotic process GO:2000351 24 0.684
Human
regulation of wound healing GO:0061041 56 0.681
Human
phospholipid metabolic process GO:0006644 99 0.675
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.674
Human
calcium mediated signaling GO:0019722 44 0.673
Human
glycerolipid biosynthetic process GO:0045017 51 0.665
adherens junction organization GO:0034332 36 0.664
Human
tyrosine phosphorylation of stat protein GO:0007260 33 0.664
Human
adherens junction assembly GO:0034333 34 0.655
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.654
Rat
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 12 0.650
positive regulation of cell matrix adhesion GO:0001954 23 0.647
Human
male genitalia development GO:0030539 1 0.643
Fly
regulation of dna metabolic process GO:0051052 153 0.641
Human Mouse
positive regulation of angiogenesis GO:0045766 51 0.640
Human
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.639
nitric oxide synthase biosynthetic process GO:0051767 6 0.639
Human
exocytosis GO:0006887 71 0.638
Human
protein localization to organelle GO:0033365 280 0.637
protein kinase b signaling GO:0043491 69 0.632
endothelial cell chemotaxis GO:0035767 13 0.631
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.631
Human
embryo development GO:0009790 123 0.630
Mouse Fly
neuron apoptotic process GO:0051402 39 0.629
polysaccharide biosynthetic process GO:0000271 27 0.627
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.626
regulation of dna replication GO:0006275 68 0.623
Human
small gtpase mediated signal transduction GO:0007264 78 0.605
regeneration GO:0031099 4 0.604
positive regulation of cellular component organization GO:0051130 376 0.603
Human Mouse
biomineral tissue development GO:0031214 39 0.602
regulation of protein kinase b signaling GO:0051896 61 0.601
kidney vasculature morphogenesis GO:0061439 1 0.591
Mouse
regulation of calcium ion transport GO:0051924 79 0.591
Mouse
endothelial cell proliferation GO:0001935 65 0.582
Human
cellular response to cytokine stimulus GO:0071345 181 0.579
Human
response to increased oxygen levels GO:0036296 4 0.574
Rat
cell projection assembly GO:0030031 126 0.573
Fly
mitotic spindle elongation GO:0000022 4 0.570
Fly
regulation of transporter activity GO:0032409 82 0.564
embryonic morphogenesis GO:0048598 85 0.563
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.561
antimicrobial humoral response GO:0019730 26 0.560
Fly
positive regulation of cytokine production GO:0001819 167 0.560
Human
positive regulation of wound healing GO:0090303 20 0.560
coagulation GO:0050817 78 0.554
Human
organophosphate biosynthetic process GO:0090407 163 0.552
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.549
renal system process involved in regulation of blood volume GO:0001977 4 0.549
actin filament organization GO:0007015 128 0.548
Fly
cellular response to stem cell factor stimulus GO:0036216 1 0.544
Human
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.542
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.541
Human
regulation of peptidase activity GO:0052547 180 0.537
negative regulation of response to wounding GO:1903035 47 0.534
Human
mitotic cell cycle process GO:1903047 286 0.533
Mouse Fly
positive regulation of mitotic cell cycle GO:0045931 60 0.531
Mouse
regulation of nucleotide metabolic process GO:0006140 269 0.524
striated muscle tissue development GO:0014706 59 0.523
Mouse
single organism cellular localization GO:1902580 332 0.515
Human
positive regulation of cell proliferation involved in kidney development GO:1901724 1 0.512
cell morphogenesis involved in differentiation GO:0000904 144 0.510
regulation of system process GO:0044057 101 0.507
cell division GO:0051301 168 0.507
Mouse
inositol lipid mediated signaling GO:0048017 55 0.506
renal system vasculature morphogenesis GO:0061438 1 0.504
Mouse
regulation of blood vessel size GO:0050880 18 0.501
response to cytokine GO:0034097 232 0.499
Human
cell development GO:0048468 328 0.498
Mouse Fly
detection of abiotic stimulus GO:0009582 15 0.496
cellular response to macrophage colony stimulating factor stimulus GO:0036006 4 0.487
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.487
regulation of cell activation GO:0050865 125 0.486
Human
kidney vasculature development GO:0061440 7 0.483
Mouse
mesenchymal cell differentiation GO:0048762 52 0.483
positive regulation of chemokine production GO:0032722 22 0.480
Human
cellular response to acid chemical GO:0071229 44 0.480
ossification GO:0001503 121 0.477
response to lipid GO:0033993 206 0.466
Rat
negative regulation of endodermal cell differentiation GO:1903225 2 0.466
positive regulation of metanephros development GO:0072216 3 0.465
Mouse
positive regulation of lipid kinase activity GO:0090218 13 0.463
mast cell migration GO:0097531 5 0.463
Human
positive regulation of cell cycle process GO:0090068 106 0.461
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.453
Human
response to insulin GO:0032868 45 0.453
Fly
positive regulation of transport GO:0051050 336 0.452
Human Mouse
negative regulation of phospholipid biosynthetic process GO:0071072 3 0.450
embryonic skeletal system morphogenesis GO:0048704 9 0.449
morphogenesis of a branching structure GO:0001763 21 0.443
regulation of mitotic cell cycle GO:0007346 189 0.442
Mouse
regulation of response to external stimulus GO:0032101 222 0.440
Human Mouse
epithelial cell differentiation GO:0030855 141 0.440
Fly
negative regulation of endothelial cell apoptotic process GO:2000352 16 0.438
Human
retina vasculature development in camera type eye GO:0061298 3 0.438
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.437
immune response regulating signaling pathway GO:0002764 97 0.436
Human
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.433
myeloid leukocyte cytokine production GO:0061082 5 0.427
Human
regulation of blood vessel endothelial cell migration GO:0043535 30 0.423
organophosphate catabolic process GO:0046434 430 0.423
regulation of polysaccharide biosynthetic process GO:0032885 20 0.421
positive regulation of endothelial cell chemotaxis GO:2001028 5 0.420
positive regulation of mitosis GO:0045840 25 0.419
Mouse
ion transmembrane transport GO:0034220 338 0.414
Mouse
multicellular organismal aging GO:0010259 3 0.414
regulation of cell morphogenesis GO:0022604 153 0.410
Human Fly
response to estrogen GO:0043627 47 0.409
Rat
regulation of cell cycle process GO:0010564 266 0.409
Mouse
immune system development GO:0002520 195 0.408
Human Fly
cell substrate junction assembly GO:0007044 35 0.408
Human
metal ion transport GO:0030001 272 0.406
Mouse
leukocyte activation GO:0045321 164 0.404
Human
metanephric nephron development GO:0072210 9 0.402
Mouse Rat
cardiac muscle tissue development GO:0048738 39 0.400
Mouse
regulation of receptor mediated endocytosis GO:0048259 32 0.399
nuclear division GO:0000280 128 0.398
Mouse
vascular process in circulatory system GO:0003018 29 0.397
vesicle mediated transport GO:0016192 371 0.392
Human
positive regulation of dna biosynthetic process GO:2000573 8 0.391
Mouse
hemopoiesis GO:0030097 180 0.382
Human Fly
chemokine production GO:0032602 32 0.381
Human
glomerulus vasculature development GO:0072012 6 0.379
Mouse
regulation of body fluid levels GO:0050878 99 0.377
Human
cellular response to dna damage stimulus GO:0006974 379 0.374
Fly
protein secretion GO:0009306 98 0.374
Human
regulation of nuclear division GO:0051783 65 0.373
Mouse
positive regulation of lipase activity GO:0060193 28 0.373
tor signaling GO:0031929 39 0.372
Fly
single organism carbohydrate metabolic process GO:0044723 193 0.367
regulation of purine nucleotide metabolic process GO:1900542 264 0.367
cell junction assembly GO:0034329 67 0.363
Human
innate immune response GO:0045087 178 0.363
Fly
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.357
purine ribonucleotide catabolic process GO:0009154 404 0.356
regulation of macrophage chemotaxis GO:0010758 4 0.355
regulation of carbohydrate biosynthetic process GO:0043255 27 0.355
positive regulation of hydrolase activity GO:0051345 331 0.354
myeloid leukocyte differentiation GO:0002573 60 0.353
cellular response to organic cyclic compound GO:0071407 127 0.353
regulation of t cell activation GO:0050863 77 0.352
cellular response to hormone stimulus GO:0032870 125 0.346
Fly
regulation of ras protein signal transduction GO:0046578 155 0.343
response to inorganic substance GO:0010035 127 0.340
Rat
leukocyte migration GO:0050900 107 0.338
Human
calcium ion homeostasis GO:0055074 122 0.337
Human
negative regulation of cell activation GO:0050866 33 0.334
Human
regulation of protein localization GO:0032880 296 0.331
Human
system process GO:0003008 349 0.329
response to oxidative stress GO:0006979 121 0.329
Rat
embryonic organ development GO:0048568 36 0.329
Mouse Fly
transmembrane transport GO:0055085 399 0.328
Mouse
fibroblast proliferation GO:0048144 33 0.327
Human
negative regulation of protein maturation GO:1903318 142 0.327
steroid metabolic process GO:0008202 94 0.326
regulation of cell cycle GO:0051726 393 0.321
Mouse
negative regulation of neuron apoptotic process GO:0043524 23 0.317
cellular homeostasis GO:0019725 196 0.317
Human
positive regulation of secretion by cell GO:1903532 108 0.315
Human
neurogenesis GO:0022008 169 0.313
regulation of cytoplasmic transport GO:1903649 149 0.312
regulation of ion transport GO:0043269 189 0.310
Mouse
regulation of secretion GO:0051046 194 0.307
Human
regulation of organ morphogenesis GO:2000027 24 0.307
growth GO:0040007 202 0.306
regulation of polysaccharide metabolic process GO:0032881 21 0.305
response to radiation GO:0009314 151 0.304
positive regulation of endocytosis GO:0045807 42 0.304
cellular metal ion homeostasis GO:0006875 146 0.303
Human
negative regulation of neuron death GO:1901215 32 0.302
cation homeostasis GO:0055080 189 0.302
Human
striated muscle cell differentiation GO:0051146 43 0.301
Mouse
regulation of endodermal cell differentiation GO:1903224 3 0.301
response to alcohol GO:0097305 64 0.301
Rat
regulation of endothelial cell chemotaxis GO:2001026 9 0.299
negative regulation of endopeptidase activity GO:0010951 84 0.299
positive regulation of cell activation GO:0050867 81 0.298

PDGFRB disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.862
Human
cancer DOID:162 167 0.819
Human
organ system cancer DOID:0050686 164 0.738
Human
musculoskeletal system disease DOID:17 223 0.656
connective tissue disease DOID:65 109 0.656
gastrointestinal system cancer DOID:3119 52 0.368
Human