Homo sapiens

0 known processes

PDHX

pyruvate dehydrogenase complex, component X

(Aliases: PDX1,proX,OPDX,E3BP,DLDBP)

PDHX biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acetyl coa metabolic process GO:0006084 8 1.000
thioester biosynthetic process GO:0035384 6 1.000
acyl coa biosynthetic process GO:0071616 6 1.000
sulfur compound biosynthetic process GO:0044272 38 0.999
sulfur compound metabolic process GO:0006790 101 0.991
acetyl coa biosynthetic process from pyruvate GO:0006086 4 0.989
acyl coa metabolic process GO:0006637 23 0.983
thioester metabolic process GO:0035383 23 0.971
coenzyme biosynthetic process GO:0009108 24 0.966
cofactor metabolic process GO:0051186 87 0.965
coenzyme metabolic process GO:0006732 65 0.933
acetyl coa biosynthetic process GO:0006085 6 0.916
monocarboxylic acid metabolic process GO:0032787 185 0.879
pyruvate metabolic process GO:0006090 26 0.749
multicellular organismal aging GO:0010259 3 0.682
determination of adult lifespan GO:0008340 2 0.669
tricarboxylic acid cycle GO:0006099 4 0.568
oxidation reduction process GO:0055114 396 0.539
sleep GO:0030431 2 0.535
post embryonic development GO:0009791 2 0.488
fatty acid metabolic process GO:0006631 115 0.318
citrate metabolic process GO:0006101 2 0.275
female gamete generation GO:0007292 2 0.213
lipid metabolic process GO:0006629 381 0.179
apoptotic mitochondrial changes GO:0008637 57 0.162
energy derivation by oxidation of organic compounds GO:0015980 43 0.157
regulation of membrane potential GO:0042391 95 0.133
aerobic respiration GO:0009060 7 0.120
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.113
oogenesis GO:0048477 2 0.109
spermatid development GO:0007286 4 0.099
small molecule biosynthetic process GO:0044283 157 0.098
cell development GO:0048468 328 0.088
regulation of proteolysis GO:0030162 293 0.086
generation of precursor metabolites and energy GO:0006091 68 0.082
ribonucleoside catabolic process GO:0042454 406 0.082
purine ribonucleoside metabolic process GO:0046128 437 0.080
cellular lipid metabolic process GO:0044255 303 0.078
nucleoside monophosphate metabolic process GO:0009123 191 0.078
cellular respiration GO:0045333 21 0.076
spermatid differentiation GO:0048515 4 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.072
nucleoside catabolic process GO:0009164 408 0.072
single organism membrane organization GO:0044802 268 0.069
purine nucleoside triphosphate metabolic process GO:0009144 412 0.065
lipid biosynthetic process GO:0008610 177 0.063
tricarboxylic acid metabolic process GO:0072350 4 0.062
purine ribonucleotide catabolic process GO:0009154 404 0.062
microtubule based process GO:0007017 210 0.059
cellular amino acid metabolic process GO:0006520 116 0.058
nucleoside triphosphate metabolic process GO:0009141 422 0.056
nucleotide catabolic process GO:0009166 408 0.056
engulfment of apoptotic cell GO:0043652 2 0.056
reactive oxygen species metabolic process GO:0072593 75 0.054
morphogenesis of embryonic epithelium GO:0016331 4 0.053
tube development GO:0035295 125 0.053
purine ribonucleoside catabolic process GO:0046130 398 0.049
organic acid biosynthetic process GO:0016053 97 0.049
receptor mediated endocytosis GO:0006898 84 0.048
cellular ketone metabolic process GO:0042180 80 0.047
ribonucleoside triphosphate catabolic process GO:0009203 391 0.047
system process GO:0003008 349 0.046
aging GO:0007568 66 0.045
membrane organization GO:0061024 292 0.042
negative regulation of cell death GO:0060548 345 0.042
ribonucleoside triphosphate metabolic process GO:0009199 412 0.040
mitochondrial membrane organization GO:0007006 40 0.040
fatty acid beta oxidation using acyl coa dehydrogenase GO:0033539 3 0.040
purine nucleoside triphosphate catabolic process GO:0009146 392 0.039
positive regulation of developmental process GO:0051094 314 0.039
endocytosis GO:0006897 159 0.039
positive regulation of programmed cell death GO:0043068 249 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.035
carboxylic acid biosynthetic process GO:0046394 97 0.034
nervous system development GO:0007399 293 0.034
embryo development GO:0009790 123 0.033
neuromuscular junction development GO:0007528 3 0.033
regulation of cell cycle GO:0051726 393 0.033
single organism membrane fusion GO:0044801 37 0.033
negative regulation of programmed cell death GO:0043069 321 0.032
gastrulation GO:0007369 51 0.032
response to oxygen containing compound GO:1901700 369 0.032
ribonucleotide catabolic process GO:0009261 405 0.031
negative regulation of apoptotic process GO:0043066 316 0.031
response to organic cyclic compound GO:0014070 204 0.031
atp metabolic process GO:0046034 176 0.031
regulation of apoptotic signaling pathway GO:2001233 175 0.030
reproductive process GO:0022414 106 0.029
cytoplasmic transport GO:0016482 379 0.029
primary neural tube formation GO:0014020 3 0.029
regulation of cellular component biogenesis GO:0044087 281 0.029
purine containing compound catabolic process GO:0072523 411 0.029
mitochondrial transport GO:0006839 60 0.028
sulfur amino acid metabolic process GO:0000096 14 0.028
positive regulation of peptidase activity GO:0010952 88 0.027
regulation of growth GO:0040008 165 0.027
growth GO:0040007 202 0.027
regulation of cellular amine metabolic process GO:0033238 11 0.027
regulation of mitochondrial membrane potential GO:0051881 23 0.027
neural tube closure GO:0001843 3 0.026
vesicle mediated transport GO:0016192 371 0.026
inorganic cation transmembrane transport GO:0098662 194 0.026
organophosphate catabolic process GO:0046434 430 0.025
amine metabolic process GO:0009308 44 0.025
cell projection organization GO:0030030 252 0.025
positive regulation of proteolysis GO:0045862 142 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
cation transmembrane transport GO:0098655 238 0.024
release of cytochrome c from mitochondria GO:0001836 35 0.024
defense response GO:0006952 315 0.023
regulation of cellular ketone metabolic process GO:0010565 50 0.023
epithelium development GO:0060429 227 0.023
cofactor biosynthetic process GO:0051188 31 0.023
tube morphogenesis GO:0035239 95 0.023
reproduction GO:0000003 63 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
regulation of cell cycle process GO:0010564 266 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
apoptotic signaling pathway GO:0097190 268 0.020
regulation of proteasomal protein catabolic process GO:0061136 87 0.020
positive regulation of catabolic process GO:0009896 310 0.019
organ formation GO:0048645 3 0.019
neuron differentiation GO:0030182 138 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
cellular amide metabolic process GO:0043603 69 0.018
apoptotic cell clearance GO:0043277 12 0.018
response to abiotic stimulus GO:0009628 336 0.018
cell morphogenesis GO:0000902 296 0.018
nucleoside triphosphate catabolic process GO:0009143 394 0.018
regulation of cellular response to growth factor stimulus GO:0090287 76 0.018
glycerophospholipid metabolic process GO:0006650 84 0.018
reproductive structure development GO:0048608 55 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
response to nutrient levels GO:0031667 81 0.017
regeneration GO:0031099 4 0.017
cellular protein catabolic process GO:0044257 261 0.017
lipid oxidation GO:0034440 33 0.017
single organism cellular localization GO:1902580 332 0.017
tube closure GO:0060606 3 0.017
protein maturation GO:0051604 233 0.016
hindbrain development GO:0030902 3 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
dephosphorylation GO:0016311 209 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
single organism reproductive process GO:0044702 98 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
embryonic morphogenesis GO:0048598 85 0.015
carboxylic acid transport GO:0046942 63 0.015
protein processing GO:0016485 226 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
metal ion transport GO:0030001 272 0.015
taxis GO:0042330 157 0.015
cellular component morphogenesis GO:0032989 314 0.015
detection of stimulus GO:0051606 85 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
response to oxidative stress GO:0006979 121 0.015
dicarboxylic acid metabolic process GO:0043648 29 0.014
cellular amine metabolic process GO:0044106 41 0.014
protein targeting GO:0006605 187 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
secretion by cell GO:0032940 226 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
regulation of response to external stimulus GO:0032101 222 0.014
protein homooligomerization GO:0051260 100 0.014
inner mitochondrial membrane organization GO:0007007 8 0.014
immune response GO:0006955 307 0.014
locomotory behavior GO:0007626 1 0.014
tissue regeneration GO:0042246 3 0.014
developmental process involved in reproduction GO:0003006 66 0.014
multi organism reproductive process GO:0044703 54 0.014
cell type specific apoptotic process GO:0097285 125 0.014
mitochondrion organization GO:0007005 156 0.014
intracellular protein transport GO:0006886 270 0.014
negative regulation of cell cycle GO:0045786 193 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
cellular carbohydrate biosynthetic process GO:0034637 21 0.014
regulation of cellular amino acid metabolic process GO:0006521 6 0.013
carbohydrate metabolic process GO:0005975 207 0.013
regulation of kinase activity GO:0043549 314 0.013
cell projection morphogenesis GO:0048858 129 0.013
response to inorganic substance GO:0010035 127 0.013
protein polymerization GO:0051258 71 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
membrane fusion GO:0061025 43 0.013
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.013
establishment of protein localization to mitochondrion GO:0072655 22 0.013
cardiovascular system development GO:0072358 262 0.013
ion homeostasis GO:0050801 230 0.013
digestive system development GO:0055123 75 0.013
regulation of cellular component movement GO:0051270 334 0.013
mitotic cell cycle phase transition GO:0044772 162 0.012
maintenance of location GO:0051235 112 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
regulation of cell growth GO:0001558 135 0.012
regulation of dna metabolic process GO:0051052 153 0.012
protein tetramerization GO:0051262 47 0.012
secretion GO:0046903 254 0.012
developmental growth GO:0048589 48 0.012
mitotic cell cycle GO:0000278 326 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
golgi vesicle transport GO:0048193 80 0.012
peripheral nervous system development GO:0007422 2 0.012
positive regulation of organelle organization GO:0010638 195 0.012
regulation of protein maturation GO:1903317 150 0.012
negative regulation of protein modification process GO:0031400 200 0.012
cell part morphogenesis GO:0032990 137 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
lipid modification GO:0030258 84 0.011
protein catabolic process GO:0030163 325 0.011
central nervous system development GO:0007417 123 0.011
compound eye development GO:0048749 1 0.011
positive regulation of developmental growth GO:0048639 16 0.011
generation of neurons GO:0048699 152 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
organic acid transport GO:0015849 65 0.011
protein localization to plasma membrane GO:0072659 93 0.011
response to reactive oxygen species GO:0000302 61 0.011
regulation of homeostatic process GO:0032844 121 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
mitotic cell cycle process GO:1903047 286 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
mitochondrial fusion GO:0008053 13 0.011
atp synthesis coupled electron transport GO:0042773 4 0.011
electron transport chain GO:0022900 8 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
cell division GO:0051301 168 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
regulation of mitochondrion organization GO:0010821 54 0.010
ras protein signal transduction GO:0007265 73 0.010
regulation of secretion GO:0051046 194 0.010
cellular response to dna damage stimulus GO:0006974 379 0.010
chemotaxis GO:0006935 157 0.010
regulation of protein localization GO:0032880 296 0.010
response to biotic stimulus GO:0009607 276 0.010
neurological system process GO:0050877 163 0.010

PDHX disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.816
amino acid metabolic disorder DOID:9252 50 0.816
inherited metabolic disorder DOID:655 242 0.816
organic acidemia DOID:0060159 14 0.156
maple syrup urine disease DOID:9269 5 0.019
carbohydrate metabolic disorder DOID:2978 55 0.018
immune system disease DOID:2914 155 0.011