Homo sapiens

0 known processes

PDIA3

protein disulfide isomerase family A, member 3

(Aliases: ERp60,ERp57,GRP58,P58,ER60,PI-PLC,GRP57,ERp61,HsT17083)

PDIA3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to unfolded protein GO:0006986 24 1.000
endoplasmic reticulum unfolded protein response GO:0030968 16 1.000
cellular response to unfolded protein GO:0034620 16 0.999
chaperone mediated protein folding GO:0061077 13 0.998
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.997
er nucleus signaling pathway GO:0006984 23 0.996
response to endoplasmic reticulum stress GO:0034976 49 0.993
cellular response to topologically incorrect protein GO:0035967 19 0.991
sensory perception of smell GO:0007608 2 0.987
response to topologically incorrect protein GO:0035966 29 0.987
cell chemotaxis GO:0060326 112 0.987
substrate adhesion dependent cell spreading GO:0034446 41 0.982
regulation of chemotaxis GO:0050920 74 0.970
4 hydroxyproline metabolic process GO:0019471 5 0.970
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.970
regulation of behavior GO:0050795 82 0.959
post embryonic development GO:0009791 2 0.946
protein folding GO:0006457 38 0.940
Yeast Worm
cellular amine metabolic process GO:0044106 41 0.929
regulation of cell migration GO:0030334 289 0.917
endodermal cell differentiation GO:0035987 31 0.914
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.911
regulation of cell adhesion GO:0030155 166 0.903
cell junction organization GO:0034330 79 0.894
salivary gland morphogenesis GO:0007435 4 0.887
mesodermal cell differentiation GO:0048333 10 0.885
leukocyte migration GO:0050900 107 0.882
cellular extravasation GO:0045123 21 0.874
ectoderm development GO:0007398 3 0.859
peptidyl tyrosine modification GO:0018212 170 0.858
chemotaxis GO:0006935 157 0.852
regulation of cellular amine metabolic process GO:0033238 11 0.836
regulation of cellular amino acid metabolic process GO:0006521 6 0.834
endoderm formation GO:0001706 33 0.827
cellular amino acid metabolic process GO:0006520 116 0.816
entry into other organism involved in symbiotic interaction GO:0051828 25 0.812
endoderm development GO:0007492 33 0.810
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.797
positive regulation of cell motility GO:2000147 177 0.795
membrane organization GO:0061024 292 0.792
positive regulation of protein phosphorylation GO:0001934 313 0.785
positive regulation of leukocyte chemotaxis GO:0002690 38 0.785
formation of primary germ layer GO:0001704 42 0.783
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.781
regulation of locomotion GO:0040012 329 0.779
regulation of cellular component movement GO:0051270 334 0.770
positive regulation of phosphorylation GO:0042327 394 0.754
biological adhesion GO:0022610 331 0.754
cell adhesion GO:0007155 325 0.753
response to transforming growth factor beta GO:0071559 94 0.749
positive regulation of cell migration GO:0030335 172 0.733
protein hydroxylation GO:0018126 9 0.728
regulation of lipoprotein metabolic process GO:0050746 7 0.720
heterotypic cell cell adhesion GO:0034113 28 0.715
regulation of cellular ketone metabolic process GO:0010565 50 0.701
sensory perception of chemical stimulus GO:0007606 38 0.697
peptidyl tyrosine phosphorylation GO:0018108 170 0.697
positive regulation of cell adhesion GO:0045785 84 0.693
regulation of leukocyte chemotaxis GO:0002688 46 0.684
taxis GO:0042330 157 0.677
sleep GO:0030431 2 0.675
positive regulation of locomotion GO:0040017 186 0.673
amine metabolic process GO:0009308 44 0.638
extracellular matrix organization GO:0030198 41 0.637
positive regulation of cell proliferation GO:0008284 301 0.637
response to hypoxia GO:0001666 96 0.631
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.615
odontogenesis GO:0042476 25 0.602
negative regulation of low density lipoprotein particle receptor biosynthetic process GO:0045715 3 0.591
positive regulation of chemotaxis GO:0050921 57 0.586
oxidation reduction process GO:0055114 396 0.578
Yeast
single organism cellular localization GO:1902580 332 0.575
response to abiotic stimulus GO:0009628 336 0.569
cellular response to growth factor stimulus GO:0071363 197 0.567
behavior GO:0007610 112 0.566
Worm
positive regulation of cellular amine metabolic process GO:0033240 7 0.565
neuronal glial interaction involved in cerebral cortex radial glia guided migration GO:0021812 1 0.562
apoptotic signaling pathway GO:0097190 268 0.561
Mouse
ameboidal type cell migration GO:0001667 135 0.550
cellular metal ion homeostasis GO:0006875 146 0.549
lipid storage GO:0019915 28 0.549
response to growth factor GO:0070848 205 0.546
regulation of growth GO:0040008 165 0.540
Worm
peptidyl proline hydroxylation GO:0019511 6 0.537
vesicle mediated transport GO:0016192 371 0.533
cerebral cortex radially oriented cell migration GO:0021799 1 0.531
regulation of lymphocyte chemotaxis GO:1901623 12 0.528
single organism cell adhesion GO:0098602 179 0.524
fat cell differentiation GO:0045444 32 0.522
integrin mediated signaling pathway GO:0007229 32 0.519
regulation of cell differentiation GO:0045595 393 0.511
regulation of translation GO:0006417 89 0.496
cell growth GO:0016049 160 0.490
cellular cation homeostasis GO:0030003 163 0.487
positive regulation of cellular component organization GO:0051130 376 0.487
circulatory system development GO:0072359 262 0.472
regulation of cell motility GO:2000145 299 0.471
leukocyte chemotaxis GO:0030595 76 0.469
endomembrane system organization GO:0010256 196 0.469
cellular ion homeostasis GO:0006873 168 0.466
growth GO:0040007 202 0.456
Worm
cellular ketone metabolic process GO:0042180 80 0.452
negative regulation of multi organism process GO:0043901 92 0.449
system process GO:0003008 349 0.448
cell junction assembly GO:0034329 67 0.446
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.439
negative regulation of apoptotic process GO:0043066 316 0.439
cell morphogenesis involved in differentiation GO:0000904 144 0.436
nail development GO:0035878 3 0.428
extracellular structure organization GO:0043062 41 0.419
negative regulation of locomotion GO:0040013 118 0.410
response to oxygen containing compound GO:1901700 369 0.408
response to decreased oxygen levels GO:0036293 96 0.405
cell substrate adhesion GO:0031589 132 0.396
lipid localization GO:0010876 106 0.393
positive regulation of dna replication GO:0045740 35 0.372
positive regulation of cellular component movement GO:0051272 181 0.372
cellular component morphogenesis GO:0032989 314 0.368
Worm
interspecies interaction between organisms GO:0044419 156 0.364
endothelial cell migration GO:0043542 86 0.363
regulation of protein binding GO:0043393 66 0.361
sequestering of calcium ion GO:0051208 17 0.360
regulation of cell morphogenesis GO:0022604 153 0.355
Worm
transmembrane transport GO:0055085 399 0.348
negative regulation of cell differentiation GO:0045596 171 0.343
single organism membrane organization GO:0044802 268 0.342
de novo protein folding GO:0006458 2 0.339
lipid catabolic process GO:0016042 84 0.334
locomotory behavior GO:0007626 1 0.333
cell morphogenesis GO:0000902 296 0.330
Worm
neuron projection development GO:0031175 106 0.320
monocyte activation GO:0042117 3 0.316
cation transport GO:0006812 331 0.315
cell substrate junction assembly GO:0007044 35 0.314
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.312
response to other organism GO:0051707 261 0.304
cellular modified amino acid metabolic process GO:0006575 64 0.301
metal ion transport GO:0030001 272 0.297
cellular response to biotic stimulus GO:0071216 71 0.296
cellular calcium ion homeostasis GO:0006874 117 0.295
entry into host GO:0044409 25 0.294
brain morphogenesis GO:0048854 1 0.292
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.280
negative regulation of cell death GO:0060548 345 0.277
positive regulation of leukocyte migration GO:0002687 46 0.277
regulation of binding GO:0051098 111 0.276
interaction with host GO:0051701 42 0.273
receptor clustering GO:0043113 9 0.271
regulation of protein stability GO:0031647 87 0.269
positive regulation of developmental process GO:0051094 314 0.268
Worm
positive regulation of developmental growth GO:0048639 16 0.267
Worm
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.266
cerebral cortex radial glia guided migration GO:0021801 1 0.265
establishment of protein localization to membrane GO:0090150 121 0.259
single organismal cell cell adhesion GO:0016337 148 0.252
lipoprotein metabolic process GO:0042157 42 0.250
renal system development GO:0072001 63 0.247
regulation of protein localization to plasma membrane GO:1903076 40 0.247
release of sequestered calcium ion into cytosol GO:0051209 41 0.245
central nervous system development GO:0007417 123 0.241
divalent inorganic cation homeostasis GO:0072507 136 0.240
regulation of axon guidance GO:1902667 3 0.235
positive regulation of cell substrate adhesion GO:0010811 37 0.233
leukocyte cell cell adhesion GO:0007159 37 0.230
positive regulation of transport GO:0051050 336 0.229
actin filament based process GO:0030029 224 0.226
ion homeostasis GO:0050801 230 0.225
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.220
Mouse
regulation of protein homodimerization activity GO:0043496 9 0.220
post embryonic organ development GO:0048569 1 0.218
neuron differentiation GO:0030182 138 0.217
maintenance of location GO:0051235 112 0.217
gastrulation GO:0007369 51 0.217
positive regulation of endocytosis GO:0045807 42 0.210
regulation of phagocytosis GO:0050764 21 0.202
regulation of cellular response to growth factor stimulus GO:0090287 76 0.199
alpha amino acid metabolic process GO:1901605 72 0.199
regulation of response to external stimulus GO:0032101 222 0.198
regulation of vesicle mediated transport GO:0060627 130 0.198
urogenital system development GO:0001655 65 0.192
nervous system development GO:0007399 293 0.191
positive regulation of protein kinase activity GO:0045860 190 0.189
cellular response to lithium ion GO:0071285 2 0.188
regulation of multi organism process GO:0043900 157 0.186
regulation of transmission of nerve impulse GO:0051969 2 0.184
dendritic cell migration GO:0036336 6 0.181
pharynx development GO:0060465 1 0.181
actin filament organization GO:0007015 128 0.179
heart development GO:0007507 95 0.179
purine ribonucleotide catabolic process GO:0009154 404 0.176
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.172
cell adhesion mediated by integrin GO:0033627 27 0.171
cardiovascular system development GO:0072358 262 0.171
plasma membrane organization GO:0007009 115 0.171
protein o linked glycosylation via serine GO:0018242 3 0.169
negative regulation of protein homodimerization activity GO:0090074 1 0.168
neurological system process GO:0050877 163 0.166
purine containing compound catabolic process GO:0072523 411 0.165
multi organism cellular process GO:0044764 156 0.164
regulation of endocytosis GO:0030100 72 0.163
protein stabilization GO:0050821 64 0.163
muscle tissue development GO:0060537 62 0.161
regulation of cell substrate adhesion GO:0010810 68 0.161
visual behavior GO:0007632 2 0.160
synaptic vesicle endocytosis GO:0048488 2 0.160
antigen processing and presentation of peptide antigen GO:0048002 18 0.159
metal ion homeostasis GO:0055065 169 0.158
regulation of epithelial cell migration GO:0010632 93 0.158
ribonucleotide catabolic process GO:0009261 405 0.157
organ morphogenesis GO:0009887 147 0.157
Worm
pericardium development GO:0060039 2 0.152
response to estrogen GO:0043627 47 0.151
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.151
intrinsic apoptotic signaling pathway GO:0097193 127 0.150
actin cytoskeleton organization GO:0030036 207 0.150
cellular divalent inorganic cation homeostasis GO:0072503 128 0.150
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.148
negative regulation of developmental process GO:0051093 247 0.148
negative regulation of protein metabolic process GO:0051248 391 0.147
response to lithium ion GO:0010226 2 0.146
endocytosis GO:0006897 159 0.144
receptor metabolic process GO:0043112 81 0.142
cell development GO:0048468 328 0.141
posttranscriptional regulation of gene expression GO:0010608 213 0.139
negative regulation of programmed cell death GO:0043069 321 0.138
regulation of homeostatic process GO:0032844 121 0.137
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 6 0.136
response to lipid GO:0033993 206 0.136
regulation of meiosis GO:0040020 3 0.135
viral entry into host cell GO:0046718 24 0.134
tissue morphogenesis GO:0048729 96 0.133
epiboly involved in wound healing GO:0090505 8 0.133
generation of neurons GO:0048699 152 0.131
epithelial cell migration GO:0010631 119 0.131
digestive system development GO:0055123 75 0.129
anoikis GO:0043276 22 0.128
wound healing spreading of epidermal cells GO:0035313 6 0.128
positive regulation of hydrolase activity GO:0051345 331 0.127
neurogenesis GO:0022008 169 0.126
monocarboxylic acid metabolic process GO:0032787 185 0.126
skin development GO:0043588 76 0.126
negative regulation of protein binding GO:0032091 35 0.126
cytosolic calcium ion transport GO:0060401 48 0.125
negative regulation of apoptotic signaling pathway GO:2001234 97 0.125
cellular response to oxygen containing compound GO:1901701 276 0.123
regulation of developmental growth GO:0048638 30 0.123
Worm
regulation of macrophage derived foam cell differentiation GO:0010743 14 0.123
divalent metal ion transport GO:0070838 152 0.123
negative regulation of binding GO:0051100 57 0.121
cellular macromolecular complex assembly GO:0034622 324 0.118
regulation of anatomical structure morphogenesis GO:0022603 286 0.118
Worm
positive regulation of establishment of protein localization to plasma membrane GO:0090004 18 0.117
optokinetic behavior GO:0007634 1 0.117
response to hormone GO:0009725 175 0.115
dephosphorylation GO:0016311 209 0.114
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.113
foam cell differentiation GO:0090077 15 0.112
cytoplasmic transport GO:0016482 379 0.111
organ formation GO:0048645 3 0.110
negative regulation of anoikis GO:2000811 15 0.108
cellular homeostasis GO:0019725 196 0.106
positive regulation of phagocytosis GO:0050766 15 0.106
organophosphate catabolic process GO:0046434 430 0.105
leukocyte activation GO:0045321 164 0.104
cellular response to external stimulus GO:0071496 111 0.103
macrophage fusion GO:0034238 1 0.103
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.102
positive regulation of cell cell adhesion GO:0022409 22 0.101
positive regulation of t cell chemotaxis GO:0010820 7 0.100
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.099
response to organophosphorus GO:0046683 41 0.099
negative regulation of multicellular organismal process GO:0051241 317 0.098
protein localization to membrane GO:0072657 160 0.098
regulation of sequestering of calcium ion GO:0051282 41 0.095
oocyte differentiation GO:0009994 2 0.095
lipid transport GO:0006869 90 0.093
movement in host environment GO:0052126 25 0.093
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.092
regulation of meiotic cell cycle GO:0051445 4 0.092
receptor mediated endocytosis GO:0006898 84 0.092
positive regulation of multicellular organism growth GO:0040018 6 0.092
Worm
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.091
collagen metabolic process GO:0032963 28 0.091
chaperone mediated protein folding requiring cofactor GO:0051085 1 0.090
regulation of purine nucleotide catabolic process GO:0033121 205 0.089
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.089
response to oxygen levels GO:0070482 100 0.088
synaptic vesicle recycling GO:0036465 3 0.088
reproduction GO:0000003 63 0.087
Worm
immune response GO:0006955 307 0.087
protein localization to plasma membrane GO:0072659 93 0.087
enzyme linked receptor protein signaling pathway GO:0007167 303 0.087
positive regulation of dna metabolic process GO:0051054 73 0.087
regulation of kinase activity GO:0043549 314 0.086
cellular response to endogenous stimulus GO:0071495 336 0.086
gland development GO:0048732 48 0.086
nephron development GO:0072006 30 0.086
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.085
positive regulation of protein localization to plasma membrane GO:1903078 20 0.084
regulation of cell cell adhesion GO:0022407 57 0.084
divalent inorganic cation transport GO:0072511 158 0.083
viral process GO:0016032 146 0.083
regulation of cell growth GO:0001558 135 0.082
antigen processing and presentation via mhc class ib GO:0002475 3 0.081
hypotonic response GO:0006971 2 0.081
intracellular receptor signaling pathway GO:0030522 104 0.081
negative regulation of cell development GO:0010721 48 0.081
calcium ion transport GO:0006816 147 0.080
regulation of collagen catabolic process GO:0010710 3 0.079
regulation of t cell migration GO:2000404 14 0.078
calcium ion transmembrane transport GO:0070588 76 0.078
response to estradiol GO:0032355 23 0.076
purine nucleoside catabolic process GO:0006152 398 0.076
cellular protein complex assembly GO:0043623 188 0.075
response to extracellular stimulus GO:0009991 85 0.074
regulation of nucleoside metabolic process GO:0009118 209 0.074
determination of adult lifespan GO:0008340 2 0.074
positive regulation of growth GO:0045927 58 0.073
Worm
negative regulation of entry of bacterium into host cell GO:2000536 1 0.073
digestive tract morphogenesis GO:0048546 56 0.072
regulation of rubidium ion transport GO:2000680 3 0.071
eye pigmentation GO:0048069 1 0.071
regulation of entry of bacterium into host cell GO:2000535 2 0.070
cation homeostasis GO:0055080 189 0.070
embryo development GO:0009790 123 0.070
Worm
developmental growth GO:0048589 48 0.070
Worm
regulation of wnt signaling pathway GO:0030111 123 0.069
cell matrix adhesion GO:0007160 85 0.069
mesoderm formation GO:0001707 10 0.068
positive regulation of substrate adhesion dependent cell spreading GO:1900026 15 0.068
response to steroid hormone GO:0048545 80 0.067
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.067
negative regulation of lipid transport GO:0032369 18 0.067
phagocytosis GO:0006909 42 0.066
tube development GO:0035295 125 0.065
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.065
positive regulation of phagocytosis engulfment GO:0060100 1 0.064
ras protein signal transduction GO:0007265 73 0.064
regulation of cell development GO:0060284 161 0.064
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.063
cerebral cortex development GO:0021987 10 0.062
regulation of apoptotic signaling pathway GO:2001233 175 0.062
Mouse
regulation of protein localization GO:0032880 296 0.061
nucleoside phosphate catabolic process GO:1901292 412 0.061
cerebral cortex cell migration GO:0021795 3 0.061
forebrain development GO:0030900 26 0.060
regulation of protein kinase activity GO:0045859 289 0.060
head development GO:0060322 108 0.059
cell activation GO:0001775 213 0.058
receptor biosynthetic process GO:0032800 18 0.058
visual learning GO:0008542 1 0.056
response to inorganic substance GO:0010035 127 0.056
tissue migration GO:0090130 119 0.056
negative chemotaxis GO:0050919 11 0.056
negative regulation of homeostatic process GO:0032845 59 0.055
regulation of cell cycle GO:0051726 393 0.055
cell cell adhesion mediated by integrin GO:0033631 8 0.055
brain development GO:0007420 97 0.055
defense response GO:0006952 315 0.054
leukocyte tethering or rolling GO:0050901 15 0.054
cell projection organization GO:0030030 252 0.054
regulation of cellular component biogenesis GO:0044087 281 0.054
regulation of phosphoprotein phosphatase activity GO:0043666 23 0.053
anatomical structure formation involved in morphogenesis GO:0048646 284 0.053
regulation of substrate adhesion dependent cell spreading GO:1900024 19 0.053
blood vessel morphogenesis GO:0048514 162 0.052
positive regulation of catabolic process GO:0009896 310 0.052
response to molecule of bacterial origin GO:0002237 82 0.052
negative regulation of nervous system development GO:0051961 28 0.051
epithelium development GO:0060429 227 0.051
regulation of establishment of protein localization GO:0070201 242 0.050
de novo posttranslational protein folding GO:0051084 2 0.050
response to drug GO:0042493 81 0.050
wound healing spreading of cells GO:0044319 8 0.050
negative regulation of cell adhesion GO:0007162 64 0.050
hemidesmosome assembly GO:0031581 5 0.049
cellular chemical homeostasis GO:0055082 180 0.049
cholesterol metabolic process GO:0008203 28 0.048
negative regulation of catalytic activity GO:0043086 335 0.048
extracellular matrix disassembly GO:0022617 16 0.048
retinoic acid receptor signaling pathway GO:0048384 13 0.047
reproductive process GO:0022414 106 0.047
Worm
translation GO:0006412 132 0.047
regulation of dephosphorylation GO:0035303 96 0.046
negative regulation of cell motility GO:2000146 104 0.046
regulation of purine nucleotide metabolic process GO:1900542 264 0.046
cellular response to hepatocyte growth factor stimulus GO:0035729 6 0.046
tissue homeostasis GO:0001894 63 0.046
morphogenesis of an epithelial sheet GO:0002011 12 0.045
sterol transport GO:0015918 39 0.045
low density lipoprotein particle receptor biosynthetic process GO:0045713 5 0.045
chordate embryonic development GO:0043009 34 0.045
neuron projection regeneration GO:0031102 1 0.044
cellular response to oxidative stress GO:0034599 85 0.044
ubiquitin dependent protein catabolic process GO:0006511 206 0.044
calcium ion homeostasis GO:0055074 122 0.044
nucleoside triphosphate catabolic process GO:0009143 394 0.044
regulation of low density lipoprotein particle receptor biosynthetic process GO:0045714 4 0.044
ion transmembrane transport GO:0034220 338 0.043
digestive tract development GO:0048565 75 0.043
response to wounding GO:0009611 168 0.043
cellular lipid catabolic process GO:0044242 65 0.043
positive regulation of behavior GO:0048520 60 0.043
axon regeneration GO:0031103 1 0.042
multicellular organismal signaling GO:0035637 34 0.042
ectodermal cell differentiation GO:0010668 3 0.042
single organism reproductive process GO:0044702 98 0.042
Worm
regulation of chemokine production GO:0032642 31 0.042
protein transmembrane transport GO:0071806 25 0.042
immune effector process GO:0002252 159 0.042
nuclear export GO:0051168 69 0.041
copper ion homeostasis GO:0055070 3 0.041
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.041
odontogenesis of dentin containing tooth GO:0042475 10 0.041
regulation of ras protein signal transduction GO:0046578 155 0.041
axon development GO:0061564 34 0.041
establishment of protein localization to plasma membrane GO:0090002 68 0.040
response to bacterium GO:0009617 144 0.040
epithelium migration GO:0090132 119 0.040
positive regulation of programmed cell death GO:0043068 249 0.039
Mouse
protein catabolic process GO:0030163 325 0.039
sequestering of metal ion GO:0051238 24 0.038
mesoderm morphogenesis GO:0048332 11 0.038
purine nucleoside triphosphate catabolic process GO:0009146 392 0.038
nucleotide catabolic process GO:0009166 408 0.038
antigen processing and presentation GO:0019882 33 0.038
phospholipid catabolic process GO:0009395 12 0.037
regulation of t cell chemotaxis GO:0010819 7 0.037
negative regulation of cell growth GO:0030308 83 0.037
regulation of phagocytosis engulfment GO:0060099 2 0.037
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.037
positive regulation of epithelial cell migration GO:0010634 55 0.037
regulation of gtpase activity GO:0043087 180 0.037
vasculature development GO:0001944 181 0.037
blood vessel development GO:0001568 172 0.036
glycoprotein biosynthetic process GO:0009101 91 0.036
negative regulation of translation GO:0017148 37 0.036
t cell chemotaxis GO:0010818 10 0.036
positive regulation of transferase activity GO:0051347 227 0.036
dendritic cell chemotaxis GO:0002407 6 0.036
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.035
cellular response to metal ion GO:0071248 43 0.035
glycosyl compound catabolic process GO:1901658 413 0.035
cardiocyte differentiation GO:0035051 23 0.034
sensory perception GO:0007600 103 0.034
angiogenesis GO:0001525 147 0.034
myeloid leukocyte activation GO:0002274 34 0.034
autophagy GO:0006914 88 0.034
regulation of nervous system development GO:0051960 88 0.034
response to biotic stimulus GO:0009607 276 0.034
body morphogenesis GO:0010171 11 0.033
Worm
protein maturation by protein folding GO:0022417 2 0.033
cortical actin cytoskeleton organization GO:0030866 9 0.033
cellular macromolecule catabolic process GO:0044265 380 0.033
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.032
receptor transactivation GO:0035624 4 0.032
purine nucleotide catabolic process GO:0006195 405 0.032
response to nitrogen compound GO:1901698 184 0.032
negative regulation of hydrolase activity GO:0051346 182 0.032
neuron development GO:0048666 113 0.032
organic hydroxy compound transport GO:0015850 63 0.031
response to axon injury GO:0048678 1 0.031
positive regulation of protein secretion GO:0050714 60 0.031
regulation of response to oxidative stress GO:1902882 26 0.031
response to heat GO:0009408 21 0.031
positive regulation of keratinocyte migration GO:0051549 4 0.030
calcium ion transport into cytosol GO:0060402 48 0.030
regulation of cellular response to oxidative stress GO:1900407 26 0.030
pigment biosynthetic process GO:0046148 10 0.030
multicellular organismal reproductive process GO:0048609 40 0.030
Worm
morphogenesis of an epithelium GO:0002009 60 0.030
response to temperature stimulus GO:0009266 22 0.030
response to metal ion GO:0010038 84 0.030

PDIA3 disease predictions

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 35 0.865
bone development disease DOID:0080006 55 0.865
bone disease DOID:0080001 88 0.865
musculoskeletal system disease DOID:17 223 0.865
connective tissue disease DOID:65 109 0.865
osteogenesis imperfecta DOID:12347 13 0.275
cancer DOID:162 167 0.084
disease of cellular proliferation DOID:14566 174 0.084
organ system cancer DOID:0050686 164 0.084
myeloma DOID:0070004 7 0.082
immune system cancer DOID:0060083 36 0.082
hematologic cancer DOID:2531 36 0.082
bone marrow cancer DOID:4960 10 0.082
primary immunodeficiency disease DOID:612 36 0.079
combined t cell and b cell immunodeficiency DOID:628 12 0.079
immune system disease DOID:2914 155 0.079
central nervous system disease DOID:331 186 0.073
nervous system disease DOID:863 431 0.073
disease of mental health DOID:150 70 0.056
cognitive disorder DOID:1561 29 0.056
disease of metabolism DOID:0014667 295 0.034
acquired metabolic disease DOID:0060158 58 0.034
neurodegenerative disease DOID:1289 102 0.033