Homo sapiens

0 known processes

PDIA6

protein disulfide isomerase family A, member 6

(Aliases: ERP5,TXNDC7,P5)

PDIA6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein folding GO:0006457 38 0.985
response to unfolded protein GO:0006986 24 0.957
Worm
post embryonic development GO:0009791 2 0.853
Worm
endoplasmic reticulum unfolded protein response GO:0030968 16 0.745
Worm
protein n linked glycosylation via asparagine GO:0018279 10 0.697
protein n linked glycosylation GO:0006487 23 0.635
negative regulation of apoptotic process GO:0043066 316 0.433
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.421
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.398
glycoprotein biosynthetic process GO:0009101 91 0.376
cellular response to unfolded protein GO:0034620 16 0.347
Worm
protein glycosylation GO:0006486 62 0.346
response to endoplasmic reticulum stress GO:0034976 49 0.290
Worm
cellular macromolecule catabolic process GO:0044265 380 0.243
regulation of peptidase activity GO:0052547 180 0.242
chaperone mediated protein folding GO:0061077 13 0.240
regulation of endopeptidase activity GO:0052548 170 0.235
protein oxidation GO:0018158 5 0.221
oxidation reduction process GO:0055114 396 0.201
negative regulation of programmed cell death GO:0043069 321 0.190
negative regulation of cell death GO:0060548 345 0.185
positive regulation of hydrolase activity GO:0051345 331 0.183
system process GO:0003008 349 0.182
modification dependent macromolecule catabolic process GO:0043632 212 0.166
response to oxygen containing compound GO:1901700 369 0.163
response to abiotic stimulus GO:0009628 336 0.160
er nucleus signaling pathway GO:0006984 23 0.159
Worm
protein catabolic process GO:0030163 325 0.158
modification dependent protein catabolic process GO:0019941 209 0.153
carbohydrate metabolic process GO:0005975 207 0.153
cellular response to oxidative stress GO:0034599 85 0.150
response to decreased oxygen levels GO:0036293 96 0.148
negative regulation of phosphorus metabolic process GO:0010563 267 0.147
vesicle mediated transport GO:0016192 371 0.144
negative regulation of hydrolase activity GO:0051346 182 0.142
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.136
ribonucleotide catabolic process GO:0009261 405 0.136
ubiquitin dependent protein catabolic process GO:0006511 206 0.135
negative regulation of cellular protein metabolic process GO:0032269 353 0.133
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.128
positive regulation of developmental process GO:0051094 314 0.127
purine nucleoside catabolic process GO:0006152 398 0.113
embryo development GO:0009790 123 0.112
negative regulation of phosphate metabolic process GO:0045936 267 0.110
glycosylation GO:0070085 71 0.110
cellular protein catabolic process GO:0044257 261 0.106
purine ribonucleoside catabolic process GO:0046130 398 0.101
cellular response to superoxide GO:0071451 6 0.098
proteasomal protein catabolic process GO:0010498 176 0.097
tissue homeostasis GO:0001894 63 0.092
endoplasmic reticulum organization GO:0007029 20 0.091
cellular response to external stimulus GO:0071496 111 0.091
response to external biotic stimulus GO:0043207 261 0.090
glycosyl compound catabolic process GO:1901658 413 0.089
regulation of purine nucleotide catabolic process GO:0033121 205 0.086
reactive oxygen species metabolic process GO:0072593 75 0.086
cellular amine metabolic process GO:0044106 41 0.085
protein maturation GO:0051604 233 0.085
negative regulation of catalytic activity GO:0043086 335 0.085
glycoprotein metabolic process GO:0009100 110 0.084
heat acclimation GO:0010286 3 0.084
purine ribonucleotide catabolic process GO:0009154 404 0.083
regulation of proteolysis GO:0030162 293 0.082
cellular modified amino acid metabolic process GO:0006575 64 0.078
single organism carbohydrate metabolic process GO:0044723 193 0.077
endocytosis GO:0006897 159 0.077
cellular response to organonitrogen compound GO:0071417 124 0.075
hindbrain development GO:0030902 3 0.074
protein processing GO:0016485 226 0.074
response to organonitrogen compound GO:0010243 156 0.073
maintenance of location GO:0051235 112 0.069
nucleoside phosphate catabolic process GO:1901292 412 0.068
cell division GO:0051301 168 0.063
regulation of cysteine type endopeptidase activity GO:2000116 127 0.062
regulation of growth GO:0040008 165 0.062
regulation of cellular component movement GO:0051270 334 0.061
response to temperature stimulus GO:0009266 22 0.060
regulation of purine nucleotide metabolic process GO:1900542 264 0.058
response to organic cyclic compound GO:0014070 204 0.058
retina homeostasis GO:0001895 42 0.058
cellular response to endogenous stimulus GO:0071495 336 0.057
carbohydrate derivative biosynthetic process GO:1901137 207 0.057
regulation of transferase activity GO:0051338 355 0.057
response to organophosphorus GO:0046683 41 0.056
negative regulation of protein metabolic process GO:0051248 391 0.056
bone development GO:0060348 26 0.055
oogenesis GO:0048477 2 0.055
hydrogen peroxide metabolic process GO:0042743 20 0.054
response to bacterium GO:0009617 144 0.053
regulation of cell motility GO:2000145 299 0.052
cellular response to hydrogen peroxide GO:0070301 37 0.051
intracellular protein transport GO:0006886 270 0.051
regulation of locomotion GO:0040012 329 0.051
ribonucleoside triphosphate metabolic process GO:0009199 412 0.050
regulation of nucleoside metabolic process GO:0009118 209 0.049
cation transport GO:0006812 331 0.049
response to inorganic substance GO:0010035 127 0.049
oocyte differentiation GO:0009994 2 0.049
cellular metal ion homeostasis GO:0006875 146 0.048
lipid localization GO:0010876 106 0.048
determination of adult lifespan GO:0008340 2 0.048
regulation of nucleotide metabolic process GO:0006140 269 0.046
regulation of phosphatase activity GO:0010921 81 0.046
posttranscriptional regulation of gene expression GO:0010608 213 0.046
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.045
regulation of atp metabolic process GO:1903578 29 0.043
negative regulation of peptidase activity GO:0010466 91 0.043
regulation of response to external stimulus GO:0032101 222 0.043
apoptotic signaling pathway GO:0097190 268 0.042
regulation of cell migration GO:0030334 289 0.042
negative regulation of protein maturation GO:1903318 142 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.039
protein transmembrane transport GO:0071806 25 0.039
skeletal system development GO:0001501 79 0.038
circulatory system process GO:0003013 113 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.038
positive regulation of kinase activity GO:0033674 204 0.038
positive regulation of protein kinase activity GO:0045860 190 0.038
receptor mediated endocytosis GO:0006898 84 0.037
regulation of protein maturation GO:1903317 150 0.037
cellular homeostasis GO:0019725 196 0.037
peptidyl asparagine modification GO:0018196 11 0.037
response to nitrogen compound GO:1901698 184 0.037
purine nucleotide catabolic process GO:0006195 405 0.036
negative regulation of phosphorylation GO:0042326 174 0.036
regulation of kinase activity GO:0043549 314 0.036
organophosphate catabolic process GO:0046434 430 0.035
multicellular organismal homeostasis GO:0048871 67 0.034
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.034
growth GO:0040007 202 0.033
response to other organism GO:0051707 261 0.033
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.033
positive regulation of growth GO:0045927 58 0.032
regulation of protein processing GO:0070613 150 0.032
regulation of cell differentiation GO:0045595 393 0.032
purine ribonucleoside metabolic process GO:0046128 437 0.032
sensory organ development GO:0007423 52 0.031
regulation of behavior GO:0050795 82 0.031
response to wounding GO:0009611 168 0.031
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.030
response to topologically incorrect protein GO:0035966 29 0.030
Worm
monocarboxylic acid metabolic process GO:0032787 185 0.030
negative regulation of multicellular organismal process GO:0051241 317 0.030
anterior posterior axis specification GO:0009948 2 0.030
cellular amino acid metabolic process GO:0006520 116 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.030
response to oxidative stress GO:0006979 121 0.029
purine containing compound catabolic process GO:0072523 411 0.029
nitrogen compound transport GO:0071705 191 0.029
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
regulation of atpase activity GO:0043462 25 0.028
regulation of membrane potential GO:0042391 95 0.028
positive regulation of nucleotide catabolic process GO:0030813 185 0.027
cytokinesis GO:0000910 96 0.027
developmental growth GO:0048589 48 0.027
nucleoside triphosphate metabolic process GO:0009141 422 0.026
actin filament organization GO:0007015 128 0.026
nucleoside monophosphate catabolic process GO:0009125 159 0.025
regulation of apoptotic signaling pathway GO:2001233 175 0.025
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.025
locomotory behavior GO:0007626 1 0.025
positive regulation of phosphorylation GO:0042327 394 0.024
response to transforming growth factor beta GO:0071559 94 0.024
reproduction GO:0000003 63 0.024
actin cytoskeleton organization GO:0030036 207 0.024
positive regulation of nucleoside metabolic process GO:0045979 186 0.024
regulation of phosphoprotein phosphatase activity GO:0043666 23 0.024
response to hypoxia GO:0001666 96 0.024
cytoplasmic transport GO:0016482 379 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
positive regulation of cell proliferation GO:0008284 301 0.023
positive regulation of cell death GO:0010942 263 0.023
intrinsic apoptotic signaling pathway GO:0097193 127 0.023
lymphocyte activation GO:0046649 133 0.023
regulation of protein ubiquitination GO:0031396 95 0.022
regulation of response to wounding GO:1903034 101 0.022
metencephalon development GO:0022037 2 0.022
multicellular organismal aging GO:0010259 3 0.022
nervous system development GO:0007399 293 0.022
single organism cellular localization GO:1902580 332 0.022
immune effector process GO:0002252 159 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.022
peptidyl cysteine modification GO:0018198 9 0.022
embryo development ending in birth or egg hatching GO:0009792 34 0.022
somitogenesis GO:0001756 2 0.022
inflammatory response GO:0006954 79 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.022
positive regulation of cytokine production GO:0001819 167 0.022
neural tube formation GO:0001841 3 0.022
dephosphorylation GO:0016311 209 0.021
nucleotide catabolic process GO:0009166 408 0.021
positive regulation of apoptotic signaling pathway GO:2001235 70 0.021
response to lipid GO:0033993 206 0.021
membrane organization GO:0061024 292 0.021
negative regulation of protein processing GO:0010955 142 0.021
positive regulation of transferase activity GO:0051347 227 0.021
alpha amino acid metabolic process GO:1901605 72 0.020
skin development GO:0043588 76 0.020
peptidyl cysteine oxidation GO:0018171 1 0.020
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.020
response to toxic substance GO:0009636 37 0.020
regulation of multi organism process GO:0043900 157 0.019
positive regulation of blood pressure GO:0045777 3 0.019
reproductive system development GO:0061458 56 0.019
cerebellar cortex development GO:0021695 1 0.019
pigment biosynthetic process GO:0046148 10 0.019
positive regulation of developmental growth GO:0048639 16 0.019
maintenance of protein location GO:0045185 57 0.019
regulation of binding GO:0051098 111 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
positive regulation of apoptotic process GO:0043065 246 0.018
negative regulation of proteolysis GO:0045861 132 0.018
cyclic nucleotide biosynthetic process GO:0009190 61 0.018
negative regulation of endopeptidase activity GO:0010951 84 0.018
cell development GO:0048468 328 0.018
sex differentiation GO:0007548 45 0.018
cellular response to toxic substance GO:0097237 4 0.017
peptide cross linking GO:0018149 12 0.017
actin filament based process GO:0030029 224 0.017
single organism membrane organization GO:0044802 268 0.017
regulation of homeostatic process GO:0032844 121 0.017
t cell activation GO:0042110 99 0.017
leukocyte activation GO:0045321 164 0.017
segmentation GO:0035282 4 0.017
eye pigmentation GO:0048069 1 0.016
regulation of cytokine production GO:0001817 232 0.016
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.016
developmental process involved in reproduction GO:0003006 66 0.016
reproductive process GO:0022414 106 0.016
protein localization to organelle GO:0033365 280 0.016
cellular response to organic cyclic compound GO:0071407 127 0.016
positive regulation of programmed cell death GO:0043068 249 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
protein stabilization GO:0050821 64 0.015
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
regulation of defense response GO:0031347 154 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
cellular response to reactive oxygen species GO:0034614 50 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
cellular response to lipid GO:0071396 127 0.015
male genitalia development GO:0030539 1 0.015
transmembrane transport GO:0055085 399 0.015
camp biosynthetic process GO:0006171 47 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.014
cell activation GO:0001775 213 0.014
pyrimidine nucleotide biosynthetic process GO:0006221 2 0.014
response to purine containing compound GO:0014074 40 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
male sex differentiation GO:0046661 25 0.014
regulation of protein stability GO:0031647 87 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.014
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.014
endomembrane system organization GO:0010256 196 0.014
mitochondrion organization GO:0007005 156 0.013
hydrogen peroxide catabolic process GO:0042744 13 0.013
response to hormone GO:0009725 175 0.013
negative regulation of transferase activity GO:0051348 124 0.013
multicellular organismal reproductive process GO:0048609 40 0.013
macromolecule glycosylation GO:0043413 63 0.013
positive regulation of catabolic process GO:0009896 310 0.013
cell chemotaxis GO:0060326 112 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
calcium mediated signaling GO:0019722 44 0.013
immune response GO:0006955 307 0.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.012
synaptic vesicle endocytosis GO:0048488 2 0.012
regulation of mitochondrial membrane potential GO:0051881 23 0.012
regulation of developmental growth GO:0048638 30 0.012
generation of neurons GO:0048699 152 0.012
oocyte development GO:0048599 1 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
multi organism reproductive process GO:0044703 54 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
lipid storage GO:0019915 28 0.012
response to biotic stimulus GO:0009607 276 0.012
regulation of blood vessel size GO:0050880 18 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.011
blood circulation GO:0008015 113 0.011
head development GO:0060322 108 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
regeneration GO:0031099 4 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
maintenance of location in cell GO:0051651 62 0.011
maintenance of protein localization in organelle GO:0072595 15 0.011
maintenance of protein location in cell GO:0032507 56 0.011
superoxide metabolic process GO:0006801 20 0.011
positive regulation of systemic arterial blood pressure GO:0003084 2 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
multicellular organism reproduction GO:0032504 42 0.011
regulation of intracellular transport GO:0032386 195 0.011
response to extracellular stimulus GO:0009991 85 0.011
response to hydrogen peroxide GO:0042542 40 0.010
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.010
negative regulation of catabolic process GO:0009895 104 0.010
positive regulation of cell differentiation GO:0045597 211 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
glycogen metabolic process GO:0005977 22 0.010
neural nucleus development GO:0048857 47 0.010
aging GO:0007568 66 0.010
positive regulation of multicellular organism growth GO:0040018 6 0.010
purine containing compound biosynthetic process GO:0072522 88 0.010
reproductive structure development GO:0048608 55 0.010

PDIA6 disease predictions

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 55 0.056
bone disease DOID:0080001 88 0.056
musculoskeletal system disease DOID:17 223 0.056
connective tissue disease DOID:65 109 0.056
central nervous system disease DOID:331 186 0.049
nervous system disease DOID:863 431 0.049
osteochondrodysplasia DOID:2256 35 0.031
cancer DOID:162 167 0.020
disease of cellular proliferation DOID:14566 174 0.020
organ system cancer DOID:0050686 164 0.020
immune system disease DOID:2914 155 0.015