|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.932
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.904
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.900
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.898
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.879
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.870
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.854
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.852
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.816
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.801
|
Mouse Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.738
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.730
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.697
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.694
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.648
|
Mouse Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.642
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.640
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.638
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.625
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.612
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.609
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.608
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.607
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.565
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.516
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.508
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.470
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.446
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.440
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.434
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.423
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.404
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.399
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.379
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.371
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.352
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.349
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.345
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.338
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.334
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.333
|
Mouse Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.332
|
|
|
|
endocytic recycling
|
GO:0032456 |
12 |
0.330
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.329
|
Yeast |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.329
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.320
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.319
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.312
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.305
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.304
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.300
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.299
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.294
|
|
|
|
memory
|
GO:0007613 |
3 |
0.289
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.286
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.285
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.278
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.271
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.252
|
|
|
|
unsaturated fatty acid biosynthetic process
|
GO:0006636 |
21 |
0.249
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.249
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.240
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.236
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.234
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.233
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.229
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.228
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.224
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.220
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.219
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.218
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.218
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.215
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.215
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.213
|
|
|
|
phospholipid catabolic process
|
GO:0009395 |
12 |
0.213
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.213
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.210
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.210
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.209
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.208
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.200
|
|
|
|
fatty acid transport
|
GO:0015908 |
25 |
0.197
|
|
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.193
|
|
|
|
negative regulation of lipid catabolic process
|
GO:0050995 |
9 |
0.191
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.191
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.185
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.184
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.183
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.182
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.182
|
Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.181
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.180
|
|
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
35 |
0.179
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.179
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.178
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.176
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
35 |
0.176
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
37 |
0.175
|
|
|
|
positive regulation of phospholipid transport
|
GO:2001140 |
4 |
0.174
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.172
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.169
|
Yeast Mouse |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.166
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.166
|
|
|
|
regulation of ceramide biosynthetic process
|
GO:2000303 |
2 |
0.165
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.165
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.164
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.163
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.163
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.161
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.158
|
Yeast |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.157
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.157
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.154
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
38 |
0.153
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.153
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.152
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.151
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.148
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.147
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.146
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.145
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.145
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.145
|
Worm |
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.144
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.144
|
|
|
|
system process
|
GO:0003008 |
349 |
0.143
|
Worm |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.143
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.142
|
Mouse |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.142
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.141
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.140
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.139
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.139
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.138
|
|
|
|
positive regulation of superoxide anion generation
|
GO:0032930 |
4 |
0.137
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.137
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.136
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.135
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.134
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.133
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.133
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.132
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.130
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.130
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.130
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.129
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.128
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.128
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.128
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.128
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.127
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.124
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.124
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.122
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.122
|
Mouse |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.120
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.116
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.111
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.110
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.110
|
|
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.108
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.106
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.106
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.105
|
Rat |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.105
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.104
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.103
|
Mouse |
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.102
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.102
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.101
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
1 |
0.099
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.098
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.098
|
Mouse |
|
|
positive regulation of glucosylceramide catabolic process
|
GO:2000753 |
1 |
0.098
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.097
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.097
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.094
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.093
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.093
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.093
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.092
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.092
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.092
|
Fly |
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.092
|
|
|
|
sphingolipid biosynthetic process
|
GO:0030148 |
18 |
0.092
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.090
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
23 |
0.090
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.089
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.089
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.089
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.088
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.088
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.087
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.087
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.085
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.083
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.083
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.082
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.082
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.082
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.081
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.081
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.081
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.081
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.080
|
|
|
|
fatty acid catabolic process
|
GO:0009062 |
29 |
0.080
|
|
|
|
monosaccharide transport
|
GO:0015749 |
32 |
0.080
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.080
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.079
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.079
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.078
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.078
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.077
|
Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.077
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.077
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.077
|
|
|
|
liposaccharide metabolic process
|
GO:1903509 |
27 |
0.076
|
|
|
|
regulation of fatty acid beta oxidation
|
GO:0031998 |
8 |
0.076
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.076
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.075
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.075
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.075
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.075
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.074
|
Worm |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.074
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.073
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.071
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.071
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.071
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.070
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.070
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.070
|
|
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.070
|
|
|
|
glycogen biosynthetic process
|
GO:0005978 |
16 |
0.070
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.070
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.069
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.069
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.069
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.068
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.068
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.068
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.067
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
3 |
0.067
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.067
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.067
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.067
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.067
|
Fly |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.066
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.066
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.066
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.066
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.065
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.065
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.065
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.064
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.064
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.064
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.063
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.063
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.063
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.063
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.063
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.063
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.063
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.062
|
|
|
|
response to food
|
GO:0032094 |
1 |
0.061
|
|
|
|
cellular carbohydrate biosynthetic process
|
GO:0034637 |
21 |
0.061
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.061
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.061
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.061
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.061
|
|
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
3 |
0.061
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.060
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.060
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.060
|
|
|
|
positive regulation of endothelial cell apoptotic process
|
GO:2000353 |
8 |
0.059
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.059
|
Yeast |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.059
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.059
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.058
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.058
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.058
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.058
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.058
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.058
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.057
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.057
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.057
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.057
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.057
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.057
|
|
|
|
carboxylic acid catabolic process
|
GO:0046395 |
71 |
0.056
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.056
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.056
|
Yeast |
|
|
muscle system process
|
GO:0003012 |
81 |
0.056
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.056
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.055
|
Mouse |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.055
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.055
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.055
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.054
|
|
|
|
viral genome replication
|
GO:0019079 |
50 |
0.054
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.054
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.054
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.054
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.053
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.053
|
Worm |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.053
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.053
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.053
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.053
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.052
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.052
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.052
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.052
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.052
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.051
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.051
|
|
|
|
negative regulation of fatty acid beta oxidation
|
GO:0031999 |
1 |
0.051
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.051
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.051
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.051
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.051
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.051
|
|
|
|
regulation of glucosylceramide catabolic process
|
GO:2000752 |
1 |
0.050
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.050
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.050
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.050
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.050
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.049
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.049
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.049
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.049
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.048
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.048
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.048
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.048
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.048
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.048
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.048
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
2 |
0.048
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.047
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.047
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.047
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.047
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.047
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.047
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.047
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.047
|
|
|
|
regulation of fatty acid oxidation
|
GO:0046320 |
9 |
0.047
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.047
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.046
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.046
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.046
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.045
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.045
|
|
|
|
glucosylceramide catabolic process
|
GO:0006680 |
2 |
0.045
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.045
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.045
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.045
|
|
|
|
otic vesicle development
|
GO:0071599 |
1 |
0.044
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.044
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.044
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.044
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.043
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.043
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.043
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.043
|
Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.043
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.042
|
|
|
|
regulation of glucose import
|
GO:0046324 |
21 |
0.042
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
27 |
0.042
|
|
|
|
organophosphate ester transport
|
GO:0015748 |
32 |
0.041
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.041
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.041
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.041
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.041
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.040
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.040
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.040
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.040
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.040
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.040
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.040
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.039
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.039
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
2 |
0.039
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.039
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.038
|
|
|
|
sphingomyelin catabolic process
|
GO:0006685 |
2 |
0.038
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.038
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.038
|
Mouse |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.038
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.037
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.037
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.036
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.036
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.036
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.036
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.036
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.035
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.035
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.035
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.035
|
Worm |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.035
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.035
|
|
|
|
ceramide metabolic process
|
GO:0006672 |
25 |
0.035
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.035
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.035
|
|
|
|
cellular defense response
|
GO:0006968 |
2 |
0.035
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.035
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.034
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.034
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.034
|
|
|
|
membrane lipid biosynthetic process
|
GO:0046467 |
27 |
0.034
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.034
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.034
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.034
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.034
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
22 |
0.034
|
|
|
|
positive regulation of nik nf kappab signaling
|
GO:1901224 |
10 |
0.034
|
|
|
|
regulation of fatty acid transport
|
GO:2000191 |
8 |
0.034
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.034
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.033
|
Mouse |
|
|
single organism carbohydrate catabolic process
|
GO:0044724 |
33 |
0.033
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.033
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.033
|
Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.033
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.033
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.033
|
|
|
|
skeletal muscle contraction
|
GO:0003009 |
16 |
0.033
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.033
|
|
|
|
hexose transport
|
GO:0008645 |
30 |
0.033
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.032
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.032
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.032
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.032
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.032
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.032
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.032
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.032
|
Mouse |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.032
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.032
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.032
|
|
|
|
muscle hypertrophy in response to stress
|
GO:0003299 |
4 |
0.032
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.032
|
|
|
|
muscle adaptation
|
GO:0043500 |
12 |
0.032
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.032
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.032
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.032
|
|
|
|
cellular polysaccharide biosynthetic process
|
GO:0033692 |
21 |
0.032
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.032
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.032
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.031
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.031
|
|
|
|
glucosylceramide metabolic process
|
GO:0006678 |
3 |
0.031
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.031
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.031
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.030
|
|
|
|
modulation by host of viral transcription
|
GO:0043921 |
20 |
0.030
|
|
|
|
regulation of sphingomyelin catabolic process
|
GO:2000754 |
1 |
0.030
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.030
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.030
|
|
|
|
regulation of glycogen metabolic process
|
GO:0070873 |
15 |
0.030
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.030
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.030
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.030
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.029
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.029
|
|
|
|
positive regulation of sphingomyelin catabolic process
|
GO:2000755 |
1 |
0.029
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.029
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.029
|
|
|
|
thymic t cell selection
|
GO:0045061 |
2 |
0.029
|
|
|
|
prostanoid metabolic process
|
GO:0006692 |
17 |
0.029
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.029
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.029
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.029
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.029
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.028
|
|
|
|
regulation of anion transport
|
GO:0044070 |
25 |
0.028
|
|
