Homo sapiens

0 known processes

PDZD11

PDZ domain containing 11

(Aliases: PDZK11,AIPP1,PISP)

PDZD11 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
aromatic amino acid family metabolic process GO:0009072 3 0.997
forebrain generation of neurons GO:0021872 3 0.993
hair follicle morphogenesis GO:0031069 2 0.980
forebrain neuron development GO:0021884 2 0.937
indole containing compound metabolic process GO:0042430 4 0.931
lung alveolus development GO:0048286 4 0.928
metencephalon development GO:0022037 2 0.834
epidermis morphogenesis GO:0048730 3 0.833
cerebellum development GO:0021549 2 0.810
hindbrain development GO:0030902 3 0.810
inorganic cation transmembrane transport GO:0098662 194 0.696
locomotory behavior GO:0007626 1 0.666
hindlimb morphogenesis GO:0035137 2 0.661
elastic fiber assembly GO:0048251 3 0.622
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.600
cellular amine metabolic process GO:0044106 41 0.597
transition metal ion transport GO:0000041 23 0.583
organic hydroxy compound metabolic process GO:1901615 147 0.543
organonitrogen compound biosynthetic process GO:1901566 200 0.540
inorganic ion transmembrane transport GO:0098660 231 0.539
cellular amino acid metabolic process GO:0006520 116 0.512
atp catabolic process GO:0006200 157 0.511
response to zinc ion GO:0010043 12 0.508
glycoprotein biosynthetic process GO:0009101 91 0.490
amine metabolic process GO:0009308 44 0.482
removal of superoxide radicals GO:0019430 6 0.479
negative regulation of metalloenzyme activity GO:0048553 1 0.473
cellular transition metal ion homeostasis GO:0046916 21 0.459
organic hydroxy compound biosynthetic process GO:1901617 71 0.458
iron ion homeostasis GO:0055072 15 0.441
cellular response to oxidative stress GO:0034599 85 0.433
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.402
reactive oxygen species metabolic process GO:0072593 75 0.396
peptidyl lysine modification GO:0018205 144 0.394
sequestering of calcium ion GO:0051208 17 0.394
cell type specific apoptotic process GO:0097285 125 0.392
apoptotic mitochondrial changes GO:0008637 57 0.367
regulation of body fluid levels GO:0050878 99 0.367
sequestering of metal ion GO:0051238 24 0.352
nucleoside phosphate catabolic process GO:1901292 412 0.351
Human
catecholamine biosynthetic process GO:0042423 4 0.342
blood vessel remodeling GO:0001974 2 0.332
transmembrane transport GO:0055085 399 0.329
cation transmembrane transport GO:0098655 238 0.324
cation transport GO:0006812 331 0.320
cellular biogenic amine metabolic process GO:0006576 34 0.320
transition metal ion homeostasis GO:0055076 31 0.315
release of cytochrome c from mitochondria GO:0001836 35 0.308
purine nucleotide catabolic process GO:0006195 405 0.296
Human
hair cycle GO:0042633 28 0.294
cellular response to oxygen radical GO:0071450 6 0.286
chemical homeostasis GO:0048878 306 0.283
negative regulation of apoptotic process GO:0043066 316 0.282
norepinephrine biosynthetic process GO:0042421 1 0.281
negative regulation of programmed cell death GO:0043069 321 0.280
ion transmembrane transport GO:0034220 338 0.275
catechol containing compound biosynthetic process GO:0009713 4 0.273
cellular response to superoxide GO:0071451 6 0.271
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.265
nucleoside triphosphate metabolic process GO:0009141 422 0.263
Human
metal ion transport GO:0030001 272 0.253
purine nucleoside triphosphate catabolic process GO:0009146 392 0.246
Human
purine nucleoside catabolic process GO:0006152 398 0.244
Human
lactation GO:0007595 3 0.244
cation homeostasis GO:0055080 189 0.240
response to oxidative stress GO:0006979 121 0.230
alpha amino acid metabolic process GO:1901605 72 0.229
regulation of atp metabolic process GO:1903578 29 0.228
glycosyl compound catabolic process GO:1901658 413 0.228
Human
response to transition metal nanoparticle GO:1990267 29 0.227
copper ion homeostasis GO:0055070 3 0.225
response to copper ion GO:0046688 8 0.224
ion homeostasis GO:0050801 230 0.223
regulation of oxidative phosphorylation GO:0002082 3 0.220
ribonucleoside monophosphate metabolic process GO:0009161 187 0.220
regulation of nucleoside metabolic process GO:0009118 209 0.219
Human
cellular divalent inorganic cation homeostasis GO:0072503 128 0.217
cellular calcium ion homeostasis GO:0006874 117 0.212
secretion GO:0046903 254 0.212
neuron apoptotic process GO:0051402 39 0.209
nucleoside catabolic process GO:0009164 408 0.207
Human
cerebellar cortex development GO:0021695 1 0.206
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.202
skin morphogenesis GO:0043589 6 0.201
apoptotic signaling pathway GO:0097190 268 0.200
cellular metal ion homeostasis GO:0006875 146 0.199
mitochondrion organization GO:0007005 156 0.199
metal ion homeostasis GO:0055065 169 0.198
ribonucleoside catabolic process GO:0042454 406 0.196
Human
cell differentiation in hindbrain GO:0021533 1 0.195
nucleoside triphosphate catabolic process GO:0009143 394 0.194
Human
negative regulation of cell death GO:0060548 345 0.189
calcium ion homeostasis GO:0055074 122 0.188
norepinephrine metabolic process GO:0042415 1 0.182
cellular ion homeostasis GO:0006873 168 0.181
positive regulation of oxidoreductase activity GO:0051353 26 0.181
ribonucleoside triphosphate catabolic process GO:0009203 391 0.179
Human
ribonucleoside monophosphate catabolic process GO:0009158 158 0.179
nucleotide catabolic process GO:0009166 408 0.178
Human
regulation of oxidoreductase activity GO:0051341 43 0.175
hair cycle process GO:0022405 12 0.173
nucleoside monophosphate catabolic process GO:0009125 159 0.170
cell projection organization GO:0030030 252 0.166
regulation of neuron death GO:1901214 56 0.163
maintenance of location GO:0051235 112 0.156
glycoprotein metabolic process GO:0009100 110 0.155
purine containing compound catabolic process GO:0072523 411 0.155
Human
superoxide metabolic process GO:0006801 20 0.151
purine nucleoside monophosphate catabolic process GO:0009128 158 0.146
tissue morphogenesis GO:0048729 96 0.143
organ morphogenesis GO:0009887 147 0.134
divalent inorganic cation homeostasis GO:0072507 136 0.133
leukocyte activation GO:0045321 164 0.130
ribonucleoside triphosphate metabolic process GO:0009199 412 0.129
Human
cellular homeostasis GO:0019725 196 0.127
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.127
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.127
cellular response to oxygen containing compound GO:1901701 276 0.123
skin development GO:0043588 76 0.123
positive regulation of metalloenzyme activity GO:0048554 2 0.123
t helper cell differentiation GO:0042093 4 0.122
cellular cation homeostasis GO:0030003 163 0.115
t cell differentiation involved in immune response GO:0002292 7 0.115
molting cycle process GO:0022404 12 0.109
epithelium development GO:0060429 227 0.108
generation of precursor metabolites and energy GO:0006091 68 0.105
purine nucleoside monophosphate metabolic process GO:0009126 186 0.104
neuron death GO:0070997 65 0.103
cellular response to reactive oxygen species GO:0034614 50 0.103
t cell activation GO:0042110 99 0.103
response to metal ion GO:0010038 84 0.102
collagen fibril organization GO:0030199 10 0.099
post embryonic development GO:0009791 2 0.096
morphogenesis of an epithelium GO:0002009 60 0.094
nucleoside monophosphate metabolic process GO:0009123 191 0.092
regulation of generation of precursor metabolites and energy GO:0043467 27 0.089
respiratory tube development GO:0030323 20 0.089
response to reactive oxygen species GO:0000302 61 0.089
cellular chemical homeostasis GO:0055082 180 0.087
appendage development GO:0048736 23 0.087
tryptophan metabolic process GO:0006568 2 0.086
cell morphogenesis involved in differentiation GO:0000904 144 0.086
cell activation GO:0001775 213 0.086
negative regulation of catalytic activity GO:0043086 335 0.085
anatomical structure formation involved in morphogenesis GO:0048646 284 0.085
response to oxygen containing compound GO:1901700 369 0.083
immune effector process GO:0002252 159 0.080
alpha beta t cell differentiation involved in immune response GO:0002293 5 0.078
response to oxygen radical GO:0000305 6 0.077
epidermis development GO:0008544 59 0.075
negative regulation of neuron apoptotic process GO:0043524 23 0.074
cell morphogenesis GO:0000902 296 0.071
central nervous system neuron development GO:0021954 7 0.070
hematopoietic or lymphoid organ development GO:0048534 186 0.070
cellular component morphogenesis GO:0032989 314 0.069
cell projection morphogenesis GO:0048858 129 0.069
t cell activation involved in immune response GO:0002286 13 0.069
cell development GO:0048468 328 0.068
hemopoiesis GO:0030097 180 0.067
immune system development GO:0002520 195 0.067
alpha beta t cell differentiation GO:0046632 7 0.065
leukocyte differentiation GO:0002521 98 0.064
phenol containing compound metabolic process GO:0018958 12 0.063
forebrain development GO:0030900 26 0.060
female gamete generation GO:0007292 2 0.059
extracellular matrix organization GO:0030198 41 0.057
lymphocyte activation GO:0046649 133 0.055
hair follicle development GO:0001942 11 0.055
behavior GO:0007610 112 0.054
connective tissue development GO:0061448 39 0.053
extracellular structure organization GO:0043062 41 0.051
skeletal system development GO:0001501 79 0.051
blood vessel development GO:0001568 172 0.050
embryo development GO:0009790 123 0.050
vasculature development GO:0001944 181 0.047
negative regulation of neuron death GO:1901215 32 0.046
cell activation involved in immune response GO:0002263 30 0.046
response to inorganic substance GO:0010035 127 0.044
cardiovascular system development GO:0072358 262 0.044
leukocyte activation involved in immune response GO:0002366 30 0.043
lung development GO:0030324 20 0.042
gland development GO:0048732 48 0.042
copper ion import GO:0015677 1 0.041
alpha beta t cell activation involved in immune response GO:0002287 5 0.040
cartilage development GO:0051216 31 0.040
generation of neurons GO:0048699 152 0.039
circulatory system development GO:0072359 262 0.039
neuron differentiation GO:0030182 138 0.039
cell part morphogenesis GO:0032990 137 0.038
neuron projection development GO:0031175 106 0.038
central nervous system development GO:0007417 123 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
pigmentation GO:0043473 22 0.036
tissue remodeling GO:0048771 16 0.035
tube development GO:0035295 125 0.035
single organism cellular localization GO:1902580 332 0.034
microtubule based process GO:0007017 210 0.034
cellular copper ion homeostasis GO:0006878 2 0.034
lipid metabolic process GO:0006629 381 0.033
neurogenesis GO:0022008 169 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.033
oogenesis GO:0048477 2 0.033
limb morphogenesis GO:0035108 16 0.032
immune response GO:0006955 307 0.032
limb development GO:0060173 23 0.032
secretion by tissue GO:0032941 9 0.032
cellular macromolecule catabolic process GO:0044265 380 0.031
dendrite development GO:0016358 24 0.031
vesicle mediated transport GO:0016192 371 0.031
protein oligomerization GO:0051259 173 0.031
cellular ketone metabolic process GO:0042180 80 0.030
respiratory system development GO:0060541 22 0.030
regulation of cellular amine metabolic process GO:0033238 11 0.030
endocytosis GO:0006897 159 0.030
oocyte differentiation GO:0009994 2 0.029
neuron development GO:0048666 113 0.028
protein processing GO:0016485 226 0.028
response to iron ion GO:0010039 6 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
indolalkylamine metabolic process GO:0006586 2 0.028
regulation of kinase activity GO:0043549 314 0.028
defense response GO:0006952 315 0.027
regulation of cell cycle GO:0051726 393 0.027
single organism membrane organization GO:0044802 268 0.026
lymphocyte differentiation GO:0030098 35 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
molting cycle GO:0042303 28 0.026
intracellular protein transport GO:0006886 270 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.025
protein catabolic process GO:0030163 325 0.024
lymphocyte activation involved in immune response GO:0002285 20 0.024
central nervous system neuron differentiation GO:0021953 9 0.024
adult locomotory behavior GO:0008344 1 0.024
cd4 positive alpha beta t cell activation GO:0035710 6 0.023
regulation of protein localization GO:0032880 296 0.023
Human
regulation of protein catabolic process GO:0042176 155 0.022
response to abiotic stimulus GO:0009628 336 0.022
cellular protein catabolic process GO:0044257 261 0.022
cytoplasmic transport GO:0016482 379 0.021
protein maturation GO:0051604 233 0.021
mammary gland development GO:0030879 17 0.021
regulation of proteolysis GO:0030162 293 0.021
catecholamine metabolic process GO:0006584 6 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
Human
regulation of establishment of protein localization GO:0070201 242 0.020
body fluid secretion GO:0007589 9 0.020
system process GO:0003008 349 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
oocyte development GO:0048599 1 0.019
protein ubiquitination GO:0016567 314 0.019
regulation of locomotion GO:0040012 329 0.019
regulation of transferase activity GO:0051338 355 0.019
negative regulation of protein metabolic process GO:0051248 391 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
multicellular organismal aging GO:0010259 3 0.018
membrane organization GO:0061024 292 0.018
positive regulation of phosphorylation GO:0042327 394 0.018
positive regulation of secretion by cell GO:1903532 108 0.018
protein homooligomerization GO:0051260 100 0.018
small molecule biosynthetic process GO:0044283 157 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
determination of adult lifespan GO:0008340 2 0.017
copper ion transport GO:0006825 3 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
protein targeting GO:0006605 187 0.017
alpha beta t cell activation GO:0046631 15 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
Human
dna repair GO:0006281 198 0.017
regulation of protein kinase activity GO:0045859 289 0.017
positive regulation of kinase activity GO:0033674 204 0.017
regulation of secretion GO:0051046 194 0.017
chromatin modification GO:0016568 298 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
chromosome segregation GO:0007059 114 0.016
positive regulation of catabolic process GO:0009896 310 0.016
Human
positive regulation of hydrolase activity GO:0051345 331 0.016
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
Human
nerve development GO:0021675 4 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
motor neuron axon guidance GO:0008045 2 0.016
regulation of cellular response to stress GO:0080135 244 0.016
dephosphorylation GO:0016311 209 0.016
neuron projection morphogenesis GO:0048812 50 0.016
sensory perception of pain GO:0019233 4 0.016
endosomal transport GO:0016197 129 0.015
regulation of growth GO:0040008 165 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
neurological system process GO:0050877 163 0.015
negative regulation of protein maturation GO:1903318 142 0.015
regulation of secretion by cell GO:1903530 177 0.015
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
nuclear transport GO:0051169 179 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
negative regulation of protein modification process GO:0031400 200 0.015
innate immune response GO:0045087 178 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
Human
oxidative phosphorylation GO:0006119 10 0.014
chromatin organization GO:0006325 351 0.014
biological adhesion GO:0022610 331 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
secretion by cell GO:0032940 226 0.014
mapk cascade GO:0000165 288 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
cranial nerve development GO:0021545 4 0.014
regulation of cell cycle process GO:0010564 266 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
Human
regulation of cell motility GO:2000145 299 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
organophosphate catabolic process GO:0046434 430 0.013
Human
signal transduction by phosphorylation GO:0023014 297 0.013
cell cycle phase transition GO:0044770 173 0.013
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.013
positive regulation of secretion GO:0051047 116 0.013
negative regulation of growth GO:0045926 97 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
Human
spermatid differentiation GO:0048515 4 0.013
mitotic cell cycle GO:0000278 326 0.013
regeneration GO:0031099 4 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
negative regulation of cell cycle GO:0045786 193 0.013
response to other organism GO:0051707 261 0.013
interspecies interaction between organisms GO:0044419 156 0.013
cell adhesion GO:0007155 325 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
positive regulation of transferase activity GO:0051347 227 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
nervous system development GO:0007399 293 0.013
mitotic cell cycle process GO:1903047 286 0.012
single organism reproductive process GO:0044702 98 0.012
viral life cycle GO:0019058 132 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
positive regulation of transport GO:0051050 336 0.012
positive regulation of cell death GO:0010942 263 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
regulation of protein maturation GO:1903317 150 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
cytokinesis GO:0000910 96 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
response to lipid GO:0033993 206 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
actin filament based process GO:0030029 224 0.012
peripheral nervous system development GO:0007422 2 0.012
chordate embryonic development GO:0043009 34 0.012
regulation of peptidase activity GO:0052547 180 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
response to radiation GO:0009314 151 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
protein localization to organelle GO:0033365 280 0.011
embryo development ending in birth or egg hatching GO:0009792 34 0.011
regulation of cellular component movement GO:0051270 334 0.011
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.011
hippocampus development GO:0021766 1 0.011
organelle localization GO:0051640 84 0.011
optic nerve development GO:0021554 2 0.011
response to external biotic stimulus GO:0043207 261 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
Human
negative regulation of cell growth GO:0030308 83 0.011
cell growth GO:0016049 160 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
negative regulation of protein processing GO:0010955 142 0.011
multi organism cellular process GO:0044764 156 0.011
regulation of cell growth GO:0001558 135 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
Human
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
regulation of response to external stimulus GO:0032101 222 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
response to cytokine GO:0034097 232 0.011
lipid localization GO:0010876 106 0.011
coenzyme metabolic process GO:0006732 65 0.011
growth GO:0040007 202 0.011
positive regulation of proteolysis GO:0045862 142 0.011
regulation of multi organism process GO:0043900 157 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
negative regulation of proteolysis GO:0045861 132 0.010
cell division GO:0051301 168 0.010
protein dephosphorylation GO:0006470 81 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
Human
visual learning GO:0008542 1 0.010
organic acid biosynthetic process GO:0016053 97 0.010
regulation of protein processing GO:0070613 150 0.010
regulation of mapk cascade GO:0043408 262 0.010
negative regulation of transferase activity GO:0051348 124 0.010
positive regulation of protein transport GO:0051222 135 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
negative regulation of transport GO:0051051 176 0.010
organelle fission GO:0048285 149 0.010
regulation of membrane potential GO:0042391 95 0.010
nucleotide biosynthetic process GO:0009165 109 0.010
rho protein signal transduction GO:0007266 26 0.010
Human
cellular response to external stimulus GO:0071496 111 0.010
positive regulation of peptidase activity GO:0010952 88 0.010
regulation of nucleocytoplasmic transport GO:0046822 98 0.010
spermatid development GO:0007286 4 0.010

PDZD11 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.948
inherited metabolic disorder DOID:655 242 0.948
metal metabolism disorder DOID:896 19 0.948
hair disease DOID:421 9 0.439
integumentary system disease DOID:16 43 0.439
central nervous system disease DOID:331 186 0.085
neurodegenerative disease DOID:1289 102 0.085
nervous system disease DOID:863 431 0.085
sensory system disease DOID:0050155 203 0.012
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012