Homo sapiens

101 known processes

PDZD3

PDZ domain containing 3

(Aliases: IKEPP,FLJ22756,PDZK2,NHERF4)

PDZD3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
receptor guanylyl cyclase signaling pathway GO:0007168 5 1.000
cyclic nucleotide metabolic process GO:0009187 82 0.999
cyclic purine nucleotide metabolic process GO:0052652 60 0.987
nucleoside phosphate biosynthetic process GO:1901293 109 0.987
ribonucleotide biosynthetic process GO:0009260 81 0.983
nucleotide biosynthetic process GO:0009165 109 0.963
purine ribonucleotide biosynthetic process GO:0009152 79 0.962
purine nucleotide biosynthetic process GO:0006164 84 0.954
purine containing compound biosynthetic process GO:0072522 88 0.929
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.829
organophosphate biosynthetic process GO:0090407 163 0.794
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.747
organonitrogen compound biosynthetic process GO:1901566 200 0.721
cgmp metabolic process GO:0046068 19 0.648
cellular response to cytokine stimulus GO:0071345 181 0.514
enzyme linked receptor protein signaling pathway GO:0007167 303 0.484
negative regulation of eosinophil migration GO:2000417 2 0.317
cgmp biosynthetic process GO:0006182 12 0.291
response to cytokine GO:0034097 232 0.276
response to toxic substance GO:0009636 37 0.275
negative regulation of eosinophil extravasation GO:2000420 1 0.248
cyclic nucleotide biosynthetic process GO:0009190 61 0.192
regulation of eosinophil extravasation GO:2000419 1 0.119
eosinophil extravasation GO:0072682 1 0.111
anion transport GO:0006820 161 0.101
Human
cation transport GO:0006812 331 0.094
Human
regulation of nucleotide biosynthetic process GO:0030808 50 0.091
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.086
metal ion transport GO:0030001 272 0.082
positive regulation of camp biosynthetic process GO:0030819 35 0.079
transmembrane transport GO:0055085 399 0.076
Human
negative regulation of cellular extravasation GO:0002692 5 0.074
response to other organism GO:0051707 261 0.070
carbohydrate derivative biosynthetic process GO:1901137 207 0.069
lipid metabolic process GO:0006629 381 0.069
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.066
chemical homeostasis GO:0048878 306 0.066
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.066
response to abiotic stimulus GO:0009628 336 0.066
cellular amino acid metabolic process GO:0006520 116 0.065
cellular lipid metabolic process GO:0044255 303 0.063
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.061
divalent metal ion transport GO:0070838 152 0.059
ion transmembrane transport GO:0034220 338 0.057
Human
ribose phosphate biosynthetic process GO:0046390 82 0.056
regulation of camp metabolic process GO:0030814 52 0.052
regulation of purine nucleotide metabolic process GO:1900542 264 0.052
immune response GO:0006955 307 0.047
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.046
post embryonic development GO:0009791 2 0.045
cellular ketone metabolic process GO:0042180 80 0.045
response to nitrogen compound GO:1901698 184 0.043
regulation of ion transport GO:0043269 189 0.041
Human
amine metabolic process GO:0009308 44 0.040
cellular chemical homeostasis GO:0055082 180 0.040
ras protein signal transduction GO:0007265 73 0.040
cytoplasmic transport GO:0016482 379 0.039
nitrogen compound transport GO:0071705 191 0.039
Human
divalent inorganic cation transport GO:0072511 158 0.038
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.038
regulation of transferase activity GO:0051338 355 0.038
positive regulation of phosphorylation GO:0042327 394 0.038
multicellular organismal aging GO:0010259 3 0.037
cellular amine metabolic process GO:0044106 41 0.037
determination of adult lifespan GO:0008340 2 0.036
negative regulation of transport GO:0051051 176 0.036
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
membrane organization GO:0061024 292 0.035
defense response GO:0006952 315 0.034
organic acid transport GO:0015849 65 0.034
Human
metal ion homeostasis GO:0055065 169 0.033
response to lipid GO:0033993 206 0.033
secretion GO:0046903 254 0.032
regulation of cellular component biogenesis GO:0044087 281 0.032
single organism membrane organization GO:0044802 268 0.032
neurological system process GO:0050877 163 0.032
regulation of transmembrane transport GO:0034762 139 0.032
Human
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.032
lipid biosynthetic process GO:0008610 177 0.032
regulation of ion transmembrane transporter activity GO:0032412 72 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.031
cation homeostasis GO:0055080 189 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.030
carbohydrate metabolic process GO:0005975 207 0.030
positive regulation of transferase activity GO:0051347 227 0.029
positive regulation of ion transport GO:0043270 87 0.029
Human
cellular homeostasis GO:0019725 196 0.029
nucleotide catabolic process GO:0009166 408 0.029
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.029
organic hydroxy compound transport GO:0015850 63 0.028
Human
negative regulation of cell proliferation GO:0008285 228 0.027
Human
regulation of transmembrane transporter activity GO:0022898 74 0.027
regulation of locomotion GO:0040012 329 0.027
organophosphate catabolic process GO:0046434 430 0.027
regulation of kinase activity GO:0043549 314 0.027
cellular ion homeostasis GO:0006873 168 0.027
protein oligomerization GO:0051259 173 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.027
cellular response to endogenous stimulus GO:0071495 336 0.027
cyclic nucleotide mediated signaling GO:0019935 26 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
muscle system process GO:0003012 81 0.026
positive regulation of hydrolase activity GO:0051345 331 0.026
oxidation reduction process GO:0055114 396 0.026
associative learning GO:0008306 1 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
nucleoside phosphate catabolic process GO:1901292 412 0.026
regulation of protein kinase activity GO:0045859 289 0.026
cellular divalent inorganic cation homeostasis GO:0072503 128 0.026
purine ribonucleotide catabolic process GO:0009154 404 0.026
negative regulation of integrin activation GO:0033624 2 0.025
positive regulation of cell proliferation GO:0008284 301 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
regulation of cellular component movement GO:0051270 334 0.025
positive regulation of camp metabolic process GO:0030816 41 0.025
regulation of secretion GO:0051046 194 0.025
regulation of response to external stimulus GO:0032101 222 0.025
single organism carbohydrate metabolic process GO:0044723 193 0.024
cellular cation homeostasis GO:0030003 163 0.024
nervous system development GO:0007399 293 0.024
regulation of protein complex assembly GO:0043254 147 0.024
negative regulation of cellular component organization GO:0051129 235 0.024
cytokine production GO:0001816 247 0.024
nucleoside catabolic process GO:0009164 408 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
dephosphorylation GO:0016311 209 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
synaptic transmission involved in micturition GO:0060084 2 0.023
neuromuscular junction development GO:0007528 3 0.023
locomotory behavior GO:0007626 1 0.023
negative regulation of protein modification process GO:0031400 200 0.022
innate immune response GO:0045087 178 0.022
memory GO:0007613 3 0.022
visual behavior GO:0007632 2 0.022
glycine import GO:0036233 1 0.022
mating GO:0007618 1 0.022
protein catabolic process GO:0030163 325 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
regulation of cellular ketone metabolic process GO:0010565 50 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
regulation of metal ion transport GO:0010959 120 0.021
cardiac muscle cell contraction GO:0086003 4 0.021
rhythmic behavior GO:0007622 2 0.021
maintenance of location GO:0051235 112 0.021
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 4 0.021
negative regulation of cell death GO:0060548 345 0.021
angiotensin activated signaling pathway GO:0038166 4 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
positive regulation of cellular component organization GO:0051130 376 0.020
cellular metal ion homeostasis GO:0006875 146 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
ribonucleotide catabolic process GO:0009261 405 0.020
female gamete generation GO:0007292 2 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
Human
micturition GO:0060073 3 0.020
circadian behavior GO:0048512 2 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
Human
regulation of nucleotide metabolic process GO:0006140 269 0.020
positive regulation of transport GO:0051050 336 0.019
Human
intracellular protein transport GO:0006886 270 0.019
blastoderm segmentation GO:0007350 2 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
regulation of intracellular transport GO:0032386 195 0.019
cellular protein catabolic process GO:0044257 261 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
regulation of cellular response to stress GO:0080135 244 0.019
sensory perception GO:0007600 103 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
calcium mediated signaling GO:0019722 44 0.019
regulation of immune response GO:0050776 201 0.018
chromatin organization GO:0006325 351 0.018
endomembrane system organization GO:0010256 196 0.018
regulation of calcium ion transport GO:0051924 79 0.018
vasodilation GO:0042311 4 0.018
actin cytoskeleton organization GO:0030036 207 0.018
establishment of protein localization to membrane GO:0090150 121 0.018
divalent inorganic cation homeostasis GO:0072507 136 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
protein localization to membrane GO:0072657 160 0.017
cellular response to organonitrogen compound GO:0071417 124 0.017
visual learning GO:0008542 1 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
mapk cascade GO:0000165 288 0.017
Human
mitotic cell cycle process GO:1903047 286 0.017
segmentation GO:0035282 4 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
oogenesis GO:0048477 2 0.017
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
regulation of cell cycle process GO:0010564 266 0.016
hindbrain development GO:0030902 3 0.016
postsynaptic membrane organization GO:0001941 2 0.016
glycerolipid metabolic process GO:0046486 107 0.016
anion transmembrane transport GO:0098656 76 0.016
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.016
regulation of response to wounding GO:1903034 101 0.016
epithelium development GO:0060429 227 0.016
monovalent inorganic cation transport GO:0015672 128 0.016
lipid transport GO:0006869 90 0.016
cellular extravasation GO:0045123 21 0.016
protein processing GO:0016485 226 0.016
actin filament based process GO:0030029 224 0.015
homeostasis of number of cells in a free living population GO:0048874 1 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
mitotic cell cycle GO:0000278 326 0.015
negative regulation of cell migration GO:0030336 102 0.015
regulation of smooth muscle cell proliferation GO:0048660 28 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
regulation of eosinophil migration GO:2000416 2 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
biological adhesion GO:0022610 331 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
negative regulation of leukocyte migration GO:0002686 14 0.015
lung alveolus development GO:0048286 4 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
response to inorganic substance GO:0010035 127 0.015
protein ubiquitination GO:0016567 314 0.015
cellular amide metabolic process GO:0043603 69 0.015
protein localization to organelle GO:0033365 280 0.015
positive regulation of catabolic process GO:0009896 310 0.015
neuroblast proliferation GO:0007405 4 0.015
regulation of leukocyte migration GO:0002685 63 0.015
i kappab kinase nf kappab signaling GO:0007249 166 0.015
angiogenesis GO:0001525 147 0.014
actin mediated cell contraction GO:0070252 12 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
dna repair GO:0006281 198 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
negative regulation of response to wounding GO:1903035 47 0.014
regulation of proteolysis GO:0030162 293 0.014
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.014
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.014
synaptic transmission glycinergic GO:0060012 1 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
Human
rho protein signal transduction GO:0007266 26 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
regulation of hormone levels GO:0010817 125 0.014
calcium ion transport GO:0006816 147 0.014
blood circulation GO:0008015 113 0.014
epithelium migration GO:0090132 119 0.014
g protein coupled receptor signaling pathway GO:0007186 207 0.014
behavioral response to ethanol GO:0048149 2 0.014
camp biosynthetic process GO:0006171 47 0.014
negative regulation of cell motility GO:2000146 104 0.014
response to metal ion GO:0010038 84 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
lipid catabolic process GO:0016042 84 0.013
small molecule biosynthetic process GO:0044283 157 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
response to oxygen containing compound GO:1901700 369 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
system process GO:0003008 349 0.013
Human
covalent chromatin modification GO:0016569 254 0.013
purine containing compound catabolic process GO:0072523 411 0.013
response to radiation GO:0009314 151 0.013
brain development GO:0007420 97 0.013
action potential GO:0001508 34 0.013
positive regulation of cell motility GO:2000147 177 0.013
protein maturation GO:0051604 233 0.013
cell cell signaling GO:0007267 155 0.013
regulation of cell motility GO:2000145 299 0.013
adult locomotory behavior GO:0008344 1 0.013
sodium ion transmembrane transport GO:0035725 59 0.013
epithelial cell proliferation GO:0050673 128 0.013
regulation of map kinase activity GO:0043405 108 0.013
organic acid biosynthetic process GO:0016053 97 0.013
negative regulation of cytokine production GO:0001818 82 0.013
amide transport GO:0042886 76 0.013
regulation of camp biosynthetic process GO:0030817 45 0.013
regulation of mapk cascade GO:0043408 262 0.013
Human
phospholipid metabolic process GO:0006644 99 0.013
regulation of cell cycle GO:0051726 393 0.013
cellular response to organic cyclic compound GO:0071407 127 0.013
cellular component morphogenesis GO:0032989 314 0.013
somatostatin signaling pathway GO:0038170 1 0.013
multi organism cellular process GO:0044764 156 0.012
epithelial cell differentiation GO:0030855 141 0.012
cation transmembrane transport GO:0098655 238 0.012
regulation of lipid metabolic process GO:0019216 96 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
anatomical structure homeostasis GO:0060249 100 0.012
smooth muscle cell proliferation GO:0048659 28 0.012
regulation of anatomical structure size GO:0090066 101 0.012
positive regulation of cell cycle GO:0045787 140 0.012
gtp catabolic process GO:0006184 237 0.012
regulation of phosphatase activity GO:0010921 81 0.012
vesicle mediated transport GO:0016192 371 0.012
metencephalon development GO:0022037 2 0.012
chromatin modification GO:0016568 298 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
epidermal cell differentiation GO:0009913 45 0.012
spermatid differentiation GO:0048515 4 0.012
regulation of glial cell differentiation GO:0045685 3 0.012
regulation of ion transmembrane transport GO:0034765 132 0.012
Human
nucleoside monophosphate catabolic process GO:0009125 159 0.012
cardiac muscle contraction GO:0060048 34 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
regulation of gtpase activity GO:0043087 180 0.012
glycine transport GO:0015816 3 0.012
histone modification GO:0016570 251 0.012
inorganic anion transmembrane transport GO:0098661 47 0.012
Human
positive regulation of intracellular transport GO:0032388 104 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
defense response to other organism GO:0098542 129 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
ion homeostasis GO:0050801 230 0.012
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.012
plasma membrane organization GO:0007009 115 0.012
immune system development GO:0002520 195 0.012
cell projection organization GO:0030030 252 0.012
Human
protein targeting GO:0006605 187 0.012
blastocyst development GO:0001824 3 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
Human
positive regulation of cellular component movement GO:0051272 181 0.011
protein acylation GO:0043543 138 0.011
regeneration GO:0031099 4 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
catecholamine secretion GO:0050432 1 0.011
single organism cellular localization GO:1902580 332 0.011
sequestering of calcium ion GO:0051208 17 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
positive regulation of kinase activity GO:0033674 204 0.011
protein homooligomerization GO:0051260 100 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
oocyte development GO:0048599 1 0.011
limbic system development GO:0021761 3 0.011
striated muscle contraction GO:0006941 52 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.011
gtp metabolic process GO:0046039 239 0.011
negative regulation of protein complex assembly GO:0031333 43 0.011
peripheral nervous system development GO:0007422 2 0.011
spermatid development GO:0007286 4 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
regulation of transporter activity GO:0032409 82 0.011
response to molecule of bacterial origin GO:0002237 82 0.011
positive regulation of developmental process GO:0051094 314 0.011
cell morphogenesis GO:0000902 296 0.011
cell projection assembly GO:0030031 126 0.011
Human
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
second messenger mediated signaling GO:0019932 78 0.011
growth GO:0040007 202 0.011
regulation of cyclase activity GO:0031279 19 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
response to biotic stimulus GO:0009607 276 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
cell adhesion GO:0007155 325 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
response to external biotic stimulus GO:0043207 261 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
Human
basement membrane organization GO:0071711 3 0.011
negative regulation of transferase activity GO:0051348 124 0.011
regulation of protein catabolic process GO:0042176 155 0.011
negative regulation of cellular component movement GO:0051271 106 0.011
regulation of cell division GO:0051302 116 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
mitochondrion organization GO:0007005 156 0.011
regulation of defense response GO:0031347 154 0.011
negative regulation of secretion GO:0051048 58 0.011
response to hormone GO:0009725 175 0.011
response to wounding GO:0009611 168 0.011
multicellular organismal homeostasis GO:0048871 67 0.010
regulation of secretion by cell GO:1903530 177 0.010
salivary gland morphogenesis GO:0007435 4 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
sodium ion transport GO:0006814 61 0.010
sequestering of metal ion GO:0051238 24 0.010
establishment of protein localization to plasma membrane GO:0090002 68 0.010
sleep GO:0030431 2 0.010
regulation of cell migration GO:0030334 289 0.010
immune response in mucosal associated lymphoid tissue GO:0002386 1 0.010
cell development GO:0048468 328 0.010
regulation of protein localization GO:0032880 296 0.010
positive regulation of neurogenesis GO:0050769 49 0.010
steroid biosynthetic process GO:0006694 46 0.010
negative regulation of response to external stimulus GO:0032102 83 0.010
microtubule based process GO:0007017 210 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
regulation of protein stability GO:0031647 87 0.010
apoptotic signaling pathway GO:0097190 268 0.010
Human
blastocyst formation GO:0001825 3 0.010
inorganic cation transmembrane transport GO:0098662 194 0.010
atp metabolic process GO:0046034 176 0.010
photoreceptor cell differentiation GO:0046530 2 0.010
glycoprotein metabolic process GO:0009100 110 0.010
negative regulation of smooth muscle cell proliferation GO:0048662 14 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.010
synaptic transmission cholinergic GO:0007271 2 0.010

PDZD3 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.022
nervous system disease DOID:863 431 0.022
disease of metabolism DOID:0014667 295 0.020
cardiovascular system disease DOID:1287 106 0.016
central nervous system disease DOID:331 186 0.015
auditory system disease DOID:2742 53 0.015
musculoskeletal system disease DOID:17 223 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
cancer DOID:162 167 0.014
eye disease DOID:5614 149 0.013
eye and adnexa disease DOID:1492 150 0.013
retinal disease DOID:5679 118 0.013
neurodegenerative disease DOID:1289 102 0.011
inherited metabolic disorder DOID:655 242 0.011
urinary system disease DOID:18 40 0.011