Homo sapiens

48 known processes

PEX12

peroxisomal biogenesis factor 12

(Aliases: PAF-3)

PEX12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein localization to peroxisome GO:0072662 15 1.000
protein targeting to peroxisome GO:0006625 15 1.000
peroxisome organization GO:0007031 28 0.994
peroxisomal transport GO:0043574 15 0.990
establishment of protein localization to peroxisome GO:0072663 15 0.987
protein import into peroxisome matrix GO:0016558 11 0.975
cerebral cortex cell migration GO:0021795 3 0.934
intracellular protein transmembrane transport GO:0065002 24 0.932
protein import into peroxisome membrane GO:0045046 5 0.863
endoplasmic reticulum organization GO:0007029 20 0.746
fatty acid metabolic process GO:0006631 115 0.732
transmembrane transport GO:0055085 399 0.732
small molecule catabolic process GO:0044282 92 0.708
cellular lipid catabolic process GO:0044242 65 0.694
protein to membrane docking GO:0022615 3 0.682
carboxylic acid catabolic process GO:0046395 71 0.647
fatty acid catabolic process GO:0009062 29 0.589
lipid catabolic process GO:0016042 84 0.575
monocarboxylic acid metabolic process GO:0032787 185 0.573
lipid oxidation GO:0034440 33 0.506
monocarboxylic acid catabolic process GO:0072329 37 0.474
protein transmembrane transport GO:0071806 25 0.473
very long chain fatty acid metabolic process GO:0000038 19 0.426
long chain fatty acid catabolic process GO:0042758 3 0.414
lipid modification GO:0030258 84 0.373
organic acid catabolic process GO:0016054 71 0.368
protein localization to organelle GO:0033365 280 0.329
establishment of protein localization to organelle GO:0072594 172 0.286
intracellular protein transport GO:0006886 270 0.286
intracellular protein transmembrane import GO:0044743 23 0.265
telencephalon cell migration GO:0022029 4 0.259
fatty acid beta oxidation GO:0006635 22 0.245
protein targeting GO:0006605 187 0.238
protein import GO:0017038 130 0.227
cytoplasmic transport GO:0016482 379 0.226
cellular lipid metabolic process GO:0044255 303 0.220
protein localization to membrane GO:0072657 160 0.220
protein import into peroxisome matrix docking GO:0016560 2 0.204
membrane organization GO:0061024 292 0.190
protein homooligomerization GO:0051260 100 0.173
pallium development GO:0021543 10 0.168
lipid metabolic process GO:0006629 381 0.150
regulation of cellular component biogenesis GO:0044087 281 0.135
single organism membrane organization GO:0044802 268 0.132
mitochondrial membrane organization GO:0007006 40 0.124
establishment of protein localization to membrane GO:0090150 121 0.123
negative regulation of protein homooligomerization GO:0032463 4 0.118
positive regulation of developmental process GO:0051094 314 0.110
protein targeting to membrane GO:0006612 42 0.107
protein homotetramerization GO:0051289 28 0.106
cerebral cortex development GO:0021987 10 0.098
regulation of protein oligomerization GO:0032459 26 0.093
oxidation reduction process GO:0055114 396 0.092
protein oligomerization GO:0051259 173 0.091
negative regulation of cellular component organization GO:0051129 235 0.086
endomembrane system organization GO:0010256 196 0.081
system process GO:0003008 349 0.080
fatty acid oxidation GO:0019395 31 0.078
cerebral cortex neuron differentiation GO:0021895 1 0.071
regulation of protein complex assembly GO:0043254 147 0.071
neurological system process GO:0050877 163 0.057
mitochondrion organization GO:0007005 156 0.055
locomotory behavior GO:0007626 1 0.053
negative regulation of protein oligomerization GO:0032460 8 0.051
neurogenesis GO:0022008 169 0.046
negative regulation of protein complex assembly GO:0031333 43 0.044
neuromuscular process GO:0050905 15 0.043
response to drug GO:0042493 81 0.042
nervous system development GO:0007399 293 0.042
histone h3 acetylation GO:0043966 45 0.041
regulation of protein homooligomerization GO:0032462 11 0.041
single organism cellular localization GO:1902580 332 0.039
ion transmembrane transport GO:0034220 338 0.039
head development GO:0060322 108 0.038
cellular amino acid metabolic process GO:0006520 116 0.038
cell development GO:0048468 328 0.038
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.037
regulation of growth GO:0040008 165 0.035
growth GO:0040007 202 0.035
purine nucleotide catabolic process GO:0006195 405 0.035
positive regulation of transcription from rna polymerase ii promoter during mitosis GO:0046022 1 0.034
nucleotide catabolic process GO:0009166 408 0.034
organic anion transport GO:0015711 103 0.033
cellular amine metabolic process GO:0044106 41 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
regulation of binding GO:0051098 111 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
positive regulation of transcription during mitosis GO:0045897 2 0.030
maintenance of protein location GO:0045185 57 0.030
forebrain development GO:0030900 26 0.030
purine containing compound catabolic process GO:0072523 411 0.029
positive regulation of catabolic process GO:0009896 310 0.029
negative regulation of protein metabolic process GO:0051248 391 0.028
peroxisomal membrane transport GO:0015919 5 0.028
telencephalon development GO:0021537 17 0.028
cellular response to dna damage stimulus GO:0006974 379 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
regulation of protein binding GO:0043393 66 0.027
glycosyl compound catabolic process GO:1901658 413 0.026
protein acetylation GO:0006473 116 0.026
nitrogen compound transport GO:0071705 191 0.026
determination of adult lifespan GO:0008340 2 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
regulation of cell cycle GO:0051726 393 0.025
organophosphate catabolic process GO:0046434 430 0.025
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
protein acylation GO:0043543 138 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
internal protein amino acid acetylation GO:0006475 101 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
neuron differentiation GO:0030182 138 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
histone acetylation GO:0016573 93 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.022
post embryonic development GO:0009791 2 0.022
amine metabolic process GO:0009308 44 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
chaperone mediated protein transport GO:0072321 5 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
regulation of mitotic cell cycle GO:0007346 189 0.021
microtubule based process GO:0007017 210 0.021
methylation GO:0032259 106 0.021
multicellular organismal aging GO:0010259 3 0.021
internal peptidyl lysine acetylation GO:0018393 97 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
peroxisome fission GO:0016559 10 0.021
membrane docking GO:0022406 13 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
cellular ketone metabolic process GO:0042180 80 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
regulation of transcription during mitosis GO:0045896 2 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
regulation of cell cycle process GO:0010564 266 0.020
macromolecule methylation GO:0043414 97 0.020
regulation of protein localization GO:0032880 296 0.019
chromatin organization GO:0006325 351 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.019
central nervous system development GO:0007417 123 0.019
regulation of kinase activity GO:0043549 314 0.019
very long chain fatty acid catabolic process GO:0042760 3 0.019
generation of neurons GO:0048699 152 0.019
lipid biosynthetic process GO:0008610 177 0.018
macromolecular complex disassembly GO:0032984 60 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
histone modification GO:0016570 251 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
regulation of cellular amine metabolic process GO:0033238 11 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
histone methylation GO:0016571 60 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
chemical homeostasis GO:0048878 306 0.017
lipid localization GO:0010876 106 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
neuron migration GO:0001764 11 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.017
cellular macromolecular complex assembly GO:0034622 324 0.016
atp catabolic process GO:0006200 157 0.016
sulfur compound metabolic process GO:0006790 101 0.016
regulation of transferase activity GO:0051338 355 0.016
cytoskeleton dependent intracellular transport GO:0030705 21 0.016
positive regulation of growth GO:0045927 58 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
mitotic cell cycle GO:0000278 326 0.016
cellular protein catabolic process GO:0044257 261 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
regulation of locomotion GO:0040012 329 0.016
cation transport GO:0006812 331 0.015
lipid transport GO:0006869 90 0.015
positive regulation of cell death GO:0010942 263 0.015
cell adhesion GO:0007155 325 0.015
histone h4 k16 acetylation GO:0043984 14 0.015
negative regulation of cell cycle GO:0045786 193 0.015
negative regulation of protein modification process GO:0031400 200 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
spermatid development GO:0007286 4 0.015
Fly
positive regulation of phosphorylation GO:0042327 394 0.015
segmentation GO:0035282 4 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
maintenance of location GO:0051235 112 0.015
peptidyl lysine acetylation GO:0018394 101 0.014
positive regulation of transport GO:0051050 336 0.014
regulation of protein catabolic process GO:0042176 155 0.014
memory GO:0007613 3 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
regulation of intracellular transport GO:0032386 195 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
protein catabolic process GO:0030163 325 0.014
defense response GO:0006952 315 0.013
female gamete generation GO:0007292 2 0.013
regulation of mapk cascade GO:0043408 262 0.013
regulation of cellular response to stress GO:0080135 244 0.013
positive regulation of transferase activity GO:0051347 227 0.013
adult locomotory behavior GO:0008344 1 0.013
covalent chromatin modification GO:0016569 254 0.013
protein methylation GO:0006479 74 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
regulation of protein kinase activity GO:0045859 289 0.013
protein alkylation GO:0008213 74 0.013
atp metabolic process GO:0046034 176 0.013
organic acid transport GO:0015849 65 0.013
cell cycle phase transition GO:0044770 173 0.013
innate immune response GO:0045087 178 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.013
hindbrain development GO:0030902 3 0.013
maintenance of protein location in cell GO:0032507 56 0.013
epithelial cell proliferation GO:0050673 128 0.013
peptidyl lysine modification GO:0018205 144 0.013
histone h4 acetylation GO:0043967 47 0.013
regulation of protein transport GO:0051223 213 0.013
regulation of cellular component movement GO:0051270 334 0.012
regulation of cell motility GO:2000145 299 0.012
blastoderm segmentation GO:0007350 2 0.012
biological adhesion GO:0022610 331 0.012
mapk cascade GO:0000165 288 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
dephosphorylation GO:0016311 209 0.012
translation GO:0006412 132 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
regulation of secretion GO:0051046 194 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
immune response GO:0006955 307 0.012
inner ear morphogenesis GO:0042472 4 0.012
response to cytokine GO:0034097 232 0.012
multi organism cellular process GO:0044764 156 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
anion transmembrane transport GO:0098656 76 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
spermatid differentiation GO:0048515 4 0.011
Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
neuromuscular junction development GO:0007528 3 0.011
regulation of secretion by cell GO:1903530 177 0.011
microtubule based movement GO:0007018 32 0.011
anion transport GO:0006820 161 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
compound eye development GO:0048749 1 0.011
regeneration GO:0031099 4 0.011
regulation of cytokine production GO:0001817 232 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
secretion by cell GO:0032940 226 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
gtp catabolic process GO:0006184 237 0.011
regulation of lipid metabolic process GO:0019216 96 0.011
regulation of cell migration GO:0030334 289 0.011
neurotransmitter secretion GO:0007269 4 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
central nervous system neuron differentiation GO:0021953 9 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
negative regulation of transport GO:0051051 176 0.011
positive regulation of immune system process GO:0002684 283 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
negative regulation of protein binding GO:0032091 35 0.011
ion homeostasis GO:0050801 230 0.011
rna interference GO:0016246 4 0.011
protein ubiquitination GO:0016567 314 0.011
Yeast
ras protein signal transduction GO:0007265 73 0.011
positive regulation of kinase activity GO:0033674 204 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
organic acid biosynthetic process GO:0016053 97 0.010
nucleoside catabolic process GO:0009164 408 0.010
metal ion transport GO:0030001 272 0.010
response to abiotic stimulus GO:0009628 336 0.010
sequestering of metal ion GO:0051238 24 0.010
long chain fatty acid metabolic process GO:0001676 30 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
oogenesis GO:0048477 2 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
rho protein signal transduction GO:0007266 26 0.010
response to oxygen containing compound GO:1901700 369 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
cellular protein complex assembly GO:0043623 188 0.010
cytokine production GO:0001816 247 0.010

PEX12 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.286
brain disease DOID:936 73 0.286
nervous system disease DOID:863 431 0.286
leukodystrophy DOID:10579 8 0.200
cerebral degeneration DOID:1443 16 0.200
musculoskeletal system disease DOID:17 223 0.018
disease of cellular proliferation DOID:14566 174 0.016
sensory system disease DOID:0050155 203 0.015
immune system disease DOID:2914 155 0.015
organ system cancer DOID:0050686 164 0.013
cancer DOID:162 167 0.013
bone disease DOID:0080001 88 0.013
connective tissue disease DOID:65 109 0.013
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
eye disease DOID:5614 149 0.012
eye and adnexa disease DOID:1492 150 0.012
retinal disease DOID:5679 118 0.012
disease of metabolism DOID:0014667 295 0.011
inherited metabolic disorder DOID:655 242 0.010
cardiovascular system disease DOID:1287 106 0.010
lipid metabolism disorder DOID:3146 26 0.003
peroxisomal disease DOID:906 5 0.001