Homo sapiens

156 known processes

PEX14

peroxisomal biogenesis factor 14

(Aliases: MGC12767,dJ734G22.2,Pex14p,NAPP2)

PEX14 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein import into peroxisome matrix GO:0016558 11 1.000
peroxisome organization GO:0007031 28 1.000
establishment of protein localization to peroxisome GO:0072663 15 1.000
peroxisomal transport GO:0043574 15 1.000
protein localization to peroxisome GO:0072662 15 1.000
protein targeting to peroxisome GO:0006625 15 1.000
intracellular protein transmembrane transport GO:0065002 24 1.000
protein import into peroxisome membrane GO:0045046 5 1.000
protein to membrane docking GO:0022615 3 1.000
Yeast
intracellular protein transmembrane import GO:0044743 23 1.000
carboxylic acid catabolic process GO:0046395 71 1.000
monocarboxylic acid catabolic process GO:0072329 37 0.999
cellular lipid catabolic process GO:0044242 65 0.999
cerebral cortex cell migration GO:0021795 3 0.999
fatty acid catabolic process GO:0009062 29 0.999
protein transmembrane transport GO:0071806 25 0.999
lipid oxidation GO:0034440 33 0.996
oxidation reduction process GO:0055114 396 0.996
small molecule catabolic process GO:0044282 92 0.995
lipid modification GO:0030258 84 0.994
lipid catabolic process GO:0016042 84 0.994
telencephalon cell migration GO:0022029 4 0.991
long chain fatty acid catabolic process GO:0042758 3 0.990
monocarboxylic acid metabolic process GO:0032787 185 0.988
transmembrane transport GO:0055085 399 0.985
very long chain fatty acid metabolic process GO:0000038 19 0.980
lipid metabolic process GO:0006629 381 0.977
fatty acid metabolic process GO:0006631 115 0.966
protein targeting GO:0006605 187 0.954
protein import GO:0017038 130 0.950
establishment of protein localization to organelle GO:0072594 172 0.948
cellular lipid metabolic process GO:0044255 303 0.945
cerebral cortex development GO:0021987 10 0.937
single organism cellular localization GO:1902580 332 0.933
protein import into peroxisome matrix docking GO:0016560 2 0.892
Yeast
protein localization to organelle GO:0033365 280 0.882
forebrain development GO:0030900 26 0.864
protein targeting to membrane GO:0006612 42 0.809
neuron migration GO:0001764 11 0.800
cytoplasmic transport GO:0016482 379 0.795
intracellular protein transport GO:0006886 270 0.785
pallium development GO:0021543 10 0.752
membrane organization GO:0061024 292 0.671
protein localization to membrane GO:0072657 160 0.649
establishment of protein localization to membrane GO:0090150 121 0.634
locomotory behavior GO:0007626 1 0.607
very long chain fatty acid catabolic process GO:0042760 3 0.602
peroxisome fission GO:0016559 10 0.589
fatty acid oxidation GO:0019395 31 0.568
diterpenoid metabolic process GO:0016101 20 0.523
forebrain cell migration GO:0021885 4 0.511
peroxisomal membrane transport GO:0015919 5 0.480
long chain fatty acid metabolic process GO:0001676 30 0.455
chaperone mediated protein transport GO:0072321 5 0.453
organic acid catabolic process GO:0016054 71 0.440
microtubule based process GO:0007017 210 0.431
nervous system development GO:0007399 293 0.424
isoprenoid metabolic process GO:0006720 39 0.407
fatty acid beta oxidation GO:0006635 22 0.406
head development GO:0060322 108 0.388
spermatid development GO:0007286 4 0.332
spermatid differentiation GO:0048515 4 0.321
retinoid metabolic process GO:0001523 18 0.317
single organism membrane organization GO:0044802 268 0.301
steroid metabolic process GO:0008202 94 0.294
central nervous system development GO:0007417 123 0.287
telencephalon development GO:0021537 17 0.282
organic hydroxy compound metabolic process GO:1901615 147 0.258
protein homotetramerization GO:0051289 28 0.255
cellular ketone metabolic process GO:0042180 80 0.228
regulation of cellular component biogenesis GO:0044087 281 0.200
cell development GO:0048468 328 0.187
terpenoid metabolic process GO:0006721 27 0.186
post embryonic development GO:0009791 2 0.181
brain development GO:0007420 97 0.173
negative regulation of protein complex assembly GO:0031333 43 0.154
membrane biogenesis GO:0044091 13 0.147
negative regulation of cellular component organization GO:0051129 235 0.144
neurogenesis GO:0022008 169 0.139
protein oligomerization GO:0051259 173 0.139
mitochondrial membrane organization GO:0007006 40 0.135
regulation of protein complex assembly GO:0043254 147 0.126
endomembrane system organization GO:0010256 196 0.113
generation of neurons GO:0048699 152 0.108
myeloid dendritic cell activation GO:0001773 4 0.103
protein homooligomerization GO:0051260 100 0.099
ribonucleotide catabolic process GO:0009261 405 0.098
ion transmembrane transport GO:0034220 338 0.095
alcohol metabolic process GO:0006066 114 0.094
response to drug GO:0042493 81 0.094
behavior GO:0007610 112 0.091
cerebral cortex neuron differentiation GO:0021895 1 0.089
purine nucleotide catabolic process GO:0006195 405 0.088
forebrain generation of neurons GO:0021872 3 0.084
protein modification by small protein conjugation GO:0032446 342 0.082
negative regulation of protein oligomerization GO:0032460 8 0.080
ribonucleoside triphosphate catabolic process GO:0009203 391 0.079
ribonucleoside monophosphate catabolic process GO:0009158 158 0.078
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.078
ribonucleoside catabolic process GO:0042454 406 0.077
purine ribonucleoside catabolic process GO:0046130 398 0.075
regulation of cellular ketone metabolic process GO:0010565 50 0.070
neuromuscular process GO:0050905 15 0.069
response to oxidative stress GO:0006979 121 0.069
dendritic cell differentiation GO:0097028 13 0.067
lipid transport GO:0006869 90 0.061
purine nucleoside monophosphate metabolic process GO:0009126 186 0.058
regulation of growth GO:0040008 165 0.057
nucleotide catabolic process GO:0009166 408 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.056
neurological system process GO:0050877 163 0.055
fatty acid alpha oxidation GO:0001561 4 0.054
growth GO:0040007 202 0.052
purine containing compound catabolic process GO:0072523 411 0.052
regulation of fatty acid oxidation GO:0046320 9 0.051
lipid biosynthetic process GO:0008610 177 0.051
purine ribonucleoside metabolic process GO:0046128 437 0.050
organelle localization GO:0051640 84 0.049
mitochondrion organization GO:0007005 156 0.048
regulation of testosterone biosynthetic process GO:2000224 2 0.048
positive regulation of lipid metabolic process GO:0045834 50 0.047
cell growth GO:0016049 160 0.047
nucleoside triphosphate catabolic process GO:0009143 394 0.045
retinal metabolic process GO:0042574 8 0.044
organelle assembly GO:0070925 176 0.043
atp catabolic process GO:0006200 157 0.042
cellular response to oxidative stress GO:0034599 85 0.041
positive regulation of catabolic process GO:0009896 310 0.041
cell division GO:0051301 168 0.041
protein tetramerization GO:0051262 47 0.041
blastoderm segmentation GO:0007350 2 0.041
organic anion transport GO:0015711 103 0.040
segmentation GO:0035282 4 0.040
organic acid biosynthetic process GO:0016053 97 0.040
hematopoietic or lymphoid organ development GO:0048534 186 0.039
forebrain neuron differentiation GO:0021879 3 0.039
determination of adult lifespan GO:0008340 2 0.037
reproductive process GO:0022414 106 0.037
regulation of lipid catabolic process GO:0050994 23 0.036
adult locomotory behavior GO:0008344 1 0.035
anion transport GO:0006820 161 0.035
nucleoside monophosphate metabolic process GO:0009123 191 0.035
positive regulation of fatty acid metabolic process GO:0045923 11 0.034
organelle fission GO:0048285 149 0.034
purine ribonucleotide catabolic process GO:0009154 404 0.033
myeloid cell differentiation GO:0030099 117 0.033
meiotic chromosome segregation GO:0045132 4 0.032
glycosyl compound catabolic process GO:1901658 413 0.032
testosterone biosynthetic process GO:0061370 2 0.032
anterior posterior axis specification GO:0009948 2 0.031
atp metabolic process GO:0046034 176 0.031
myeloid dendritic cell differentiation GO:0043011 3 0.031
anterior posterior axis specification embryo GO:0008595 2 0.031
nucleoside triphosphate metabolic process GO:0009141 422 0.030
central nervous system neuron differentiation GO:0021953 9 0.030
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
neuron fate commitment GO:0048663 2 0.029
multicellular organismal aging GO:0010259 3 0.029
regulation of neuroblast proliferation GO:1902692 3 0.028
regulation of neural precursor cell proliferation GO:2000177 4 0.028
system process GO:0003008 349 0.028
cellular macromolecular complex assembly GO:0034622 324 0.027
leukocyte activation GO:0045321 164 0.027
fatty acid transport GO:0015908 25 0.026
actin filament based process GO:0030029 224 0.026
hemopoiesis GO:0030097 180 0.026
actin cytoskeleton organization GO:0030036 207 0.026
myeloid leukocyte activation GO:0002274 34 0.026
lipid localization GO:0010876 106 0.025
cellular protein complex assembly GO:0043623 188 0.024
protein monoubiquitination GO:0006513 39 0.024
anion transmembrane transport GO:0098656 76 0.024
memory GO:0007613 3 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
monocarboxylic acid transport GO:0015718 32 0.024
regulation of lipid metabolic process GO:0019216 96 0.024
negative regulation of apoptotic process GO:0043066 316 0.024
immune system development GO:0002520 195 0.024
negative regulation of cell death GO:0060548 345 0.024
mitotic cell cycle GO:0000278 326 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.024
circadian behavior GO:0048512 2 0.023
regulation of cell cycle process GO:0010564 266 0.023
regulation of cell cycle GO:0051726 393 0.023
protein folding GO:0006457 38 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
negative regulation of neural precursor cell proliferation GO:2000178 1 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
positive regulation of developmental process GO:0051094 314 0.021
salivary gland morphogenesis GO:0007435 4 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
neuron differentiation GO:0030182 138 0.021
positive regulation of growth GO:0045927 58 0.020
regulation of protein stability GO:0031647 87 0.020
response to organic cyclic compound GO:0014070 204 0.020
oocyte development GO:0048599 1 0.020
organophosphate catabolic process GO:0046434 430 0.019
cellular amine metabolic process GO:0044106 41 0.019
negative regulation of stem cell proliferation GO:2000647 3 0.019
amine metabolic process GO:0009308 44 0.019
purine nucleoside monophosphate catabolic process GO:0009128 158 0.019
nucleoside monophosphate catabolic process GO:0009125 159 0.019
positive regulation of multicellular organism growth GO:0040018 6 0.019
regulation of growth rate GO:0040009 1 0.019
cellular amino acid metabolic process GO:0006520 116 0.019
leukocyte differentiation GO:0002521 98 0.019
neuroblast proliferation GO:0007405 4 0.019
protein polyubiquitination GO:0000209 110 0.019
organophosphate biosynthetic process GO:0090407 163 0.019
response to toxic substance GO:0009636 37 0.019
organic cation transport GO:0015695 13 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
hindbrain development GO:0030902 3 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.018
protein localization to endoplasmic reticulum GO:0070972 19 0.018
small molecule biosynthetic process GO:0044283 157 0.018
negative regulation of cell proliferation GO:0008285 228 0.018
secretion by cell GO:0032940 226 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
regulation of synaptic plasticity GO:0048167 3 0.018
protein ubiquitination GO:0016567 314 0.017
purine containing compound transmembrane transport GO:0072530 6 0.017
regulation of steroid metabolic process GO:0019218 32 0.017
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
startle response GO:0001964 3 0.017
peripheral nervous system development GO:0007422 2 0.017
regulation of cytoskeleton organization GO:0051493 177 0.016
oocyte differentiation GO:0009994 2 0.016
actin filament organization GO:0007015 128 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
nucleoside catabolic process GO:0009164 408 0.016
multi organism reproductive process GO:0044703 54 0.016
regulation of cholesterol metabolic process GO:0090181 4 0.016
sensory perception of pain GO:0019233 4 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
chromatin organization GO:0006325 351 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
developmental growth GO:0048589 48 0.015
regulation of cellular component movement GO:0051270 334 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
negative regulation of mitotic cell cycle GO:0045930 102 0.015
regulation of cellular component size GO:0032535 82 0.015
organic acid transport GO:0015849 65 0.015
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.015
myeloid leukocyte differentiation GO:0002573 60 0.015
regulation of multi organism process GO:0043900 157 0.015
protein complex disassembly GO:0043241 52 0.014
morphogenesis of a polarized epithelium GO:0001738 3 0.014
regeneration GO:0031099 4 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
response to fungus GO:0009620 4 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
embryonic camera type eye formation GO:0060900 2 0.014
regulation of response to external stimulus GO:0032101 222 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
rhythmic behavior GO:0007622 2 0.014
positive regulation of transferase activity GO:0051347 227 0.014
single organism reproductive process GO:0044702 98 0.014
positive regulation of lipid catabolic process GO:0050996 13 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
developmental process involved in reproduction GO:0003006 66 0.013
cell activation GO:0001775 213 0.013
regulation of steroid biosynthetic process GO:0050810 23 0.013
rho protein signal transduction GO:0007266 26 0.013
synaptic vesicle endocytosis GO:0048488 2 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
regulation of locomotion GO:0040012 329 0.013
interspecies interaction between organisms GO:0044419 156 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
intracellular mrna localization GO:0008298 1 0.013
microtubule anchoring GO:0034453 24 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
sulfur compound metabolic process GO:0006790 101 0.013
protein stabilization GO:0050821 64 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
axon cargo transport GO:0008088 2 0.012
regulation of developmental growth GO:0048638 30 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
autophagy GO:0006914 88 0.012
ribonucleoprotein complex biogenesis GO:0022613 116 0.012
negative regulation of developmental process GO:0051093 247 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
embryonic hindlimb morphogenesis GO:0035116 2 0.012
regulation of cell motility GO:2000145 299 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
maintenance of location GO:0051235 112 0.012
associative learning GO:0008306 1 0.012
regulation of cellular response to stress GO:0080135 244 0.012
gtp metabolic process GO:0046039 239 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
long chain fatty acid transport GO:0015909 18 0.012
cardiac muscle cell contraction GO:0086003 4 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
nucleoside phosphate biosynthetic process GO:1901293 109 0.011
compound eye development GO:0048749 1 0.011
cranial nerve development GO:0021545 4 0.011
response to axon injury GO:0048678 1 0.011
regulation of multicellular organism growth GO:0040014 8 0.011
hyperosmotic response GO:0006972 4 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
negative regulation of cell cycle GO:0045786 193 0.011
purine nucleoside transmembrane transport GO:0015860 6 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
multi organism behavior GO:0051705 14 0.011
mitotic cell cycle process GO:1903047 286 0.011
visual learning GO:0008542 1 0.011
cell cycle phase transition GO:0044770 173 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
atp transport GO:0015867 4 0.011
nuclear division GO:0000280 128 0.011
mating GO:0007618 1 0.011
cell morphogenesis GO:0000902 296 0.011
protein polymerization GO:0051258 71 0.011
ras protein signal transduction GO:0007265 73 0.011
convergent extension GO:0060026 1 0.011
cell projection organization GO:0030030 252 0.010
protein catabolic process GO:0030163 325 0.010
positive regulation of kinase activity GO:0033674 204 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.010
neuromuscular junction development GO:0007528 3 0.010
viral life cycle GO:0019058 132 0.010
regulation of cellular amine metabolic process GO:0033238 11 0.010
hormone metabolic process GO:0042445 61 0.010
nuclear transport GO:0051169 179 0.010

PEX14 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.706
nervous system disease DOID:863 431 0.706
cerebral degeneration DOID:1443 16 0.399
brain disease DOID:936 73 0.399
leukodystrophy DOID:10579 8 0.399
disease of metabolism DOID:0014667 295 0.171
lipid metabolism disorder DOID:3146 26 0.092
inherited metabolic disorder DOID:655 242 0.092
musculoskeletal system disease DOID:17 223 0.030
myopathy DOID:423 104 0.020
muscular disease DOID:0080000 114 0.020
muscle tissue disease DOID:66 113 0.020
neurodegenerative disease DOID:1289 102 0.016
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
neuropathy DOID:870 52 0.013
cardiovascular system disease DOID:1287 106 0.013
immune system disease DOID:2914 155 0.011
neuromuscular disease DOID:440 38 0.011