Homo sapiens

6 known processes

PHGDH

phosphoglycerate dehydrogenase

(Aliases: PGD,3-PGDH,PGAD,PGDH,MGC3017,SERA,PDG,3PGDH)

PHGDH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dicarboxylic acid metabolic process GO:0043648 29 0.472
alpha amino acid metabolic process GO:1901605 72 0.362
Mouse
response to oxygen containing compound GO:1901700 369 0.195
alanine metabolic process GO:0006522 4 0.194
post embryonic development GO:0009791 2 0.129
alpha amino acid catabolic process GO:1901606 26 0.127
coenzyme metabolic process GO:0006732 65 0.124
organonitrogen compound biosynthetic process GO:1901566 200 0.108
small molecule catabolic process GO:0044282 92 0.097
cofactor metabolic process GO:0051186 87 0.094
cellular amino acid metabolic process GO:0006520 116 0.089
Mouse
serine family amino acid metabolic process GO:0009069 12 0.083
Mouse
organic acid biosynthetic process GO:0016053 97 0.076
water soluble vitamin metabolic process GO:0006767 6 0.072
negative regulation of programmed cell death GO:0043069 321 0.068
amine metabolic process GO:0009308 44 0.068
cellular amino acid catabolic process GO:0009063 31 0.067
carboxylic acid catabolic process GO:0046395 71 0.063
negative regulation of cell death GO:0060548 345 0.062
negative regulation of apoptotic process GO:0043066 316 0.061
cellular response to oxygen containing compound GO:1901701 276 0.061
regulation of cell cycle GO:0051726 393 0.060
chemical homeostasis GO:0048878 306 0.060
one carbon metabolic process GO:0006730 1 0.059
nitrogen compound transport GO:0071705 191 0.059
oxidation reduction process GO:0055114 396 0.059
Rat
small molecule biosynthetic process GO:0044283 157 0.058
regulation of cellular amino acid metabolic process GO:0006521 6 0.057
female gamete generation GO:0007292 2 0.056
regulation of cellular ketone metabolic process GO:0010565 50 0.056
protein oligomerization GO:0051259 173 0.056
organic acid catabolic process GO:0016054 71 0.054
response to nitrogen compound GO:1901698 184 0.053
oogenesis GO:0048477 2 0.052
response to organonitrogen compound GO:0010243 156 0.051
cellular amine metabolic process GO:0044106 41 0.049
cellular ketone metabolic process GO:0042180 80 0.049
negative regulation of protein metabolic process GO:0051248 391 0.046
negative regulation of catalytic activity GO:0043086 335 0.044
regulation of cellular amine metabolic process GO:0033238 11 0.044
cellular response to endogenous stimulus GO:0071495 336 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
cellular modified amino acid metabolic process GO:0006575 64 0.040
carbohydrate metabolic process GO:0005975 207 0.039
positive regulation of cellular amine metabolic process GO:0033240 7 0.039
response to lipid GO:0033993 206 0.039
negative regulation of cellular component organization GO:0051129 235 0.038
l serine metabolic process GO:0006563 5 0.038
Mouse
purine nucleobase biosynthetic process GO:0009113 3 0.038
lipid biosynthetic process GO:0008610 177 0.037
proline transport GO:0015824 4 0.036
regulation of protein kinase activity GO:0045859 289 0.036
mitotic cell cycle process GO:1903047 286 0.036
cellular macromolecule catabolic process GO:0044265 380 0.036
mapk cascade GO:0000165 288 0.034
regulation of hormone secretion GO:0046883 57 0.033
regulation of hormone levels GO:0010817 125 0.032
signal transduction by phosphorylation GO:0023014 297 0.032
negative regulation of phosphate metabolic process GO:0045936 267 0.032
mitotic cell cycle GO:0000278 326 0.032
transmembrane transport GO:0055085 399 0.032
ion transmembrane transport GO:0034220 338 0.032
cell development GO:0048468 328 0.032
Mouse
pyruvate family amino acid metabolic process GO:0009078 4 0.032
sulfur compound biosynthetic process GO:0044272 38 0.032
single organism carbohydrate metabolic process GO:0044723 193 0.031
regulation of mitotic cell cycle GO:0007346 189 0.031
cellular modified amino acid catabolic process GO:0042219 4 0.031
cellular response to dna damage stimulus GO:0006974 379 0.031
enzyme linked receptor protein signaling pathway GO:0007167 303 0.030
system process GO:0003008 349 0.030
positive regulation of transport GO:0051050 336 0.030
cellular response to hormone stimulus GO:0032870 125 0.030
response to external biotic stimulus GO:0043207 261 0.030
apoptotic signaling pathway GO:0097190 268 0.029
regulation of kinase activity GO:0043549 314 0.029
nucleobase biosynthetic process GO:0046112 4 0.029
cell type specific apoptotic process GO:0097285 125 0.029
carboxylic acid biosynthetic process GO:0046394 97 0.029
cytokine production GO:0001816 247 0.029
regulation of cell cycle process GO:0010564 266 0.029
posttranscriptional regulation of gene expression GO:0010608 213 0.028
negative regulation of multicellular organismal process GO:0051241 317 0.028
positive regulation of secretion by cell GO:1903532 108 0.028
positive regulation of phosphorylation GO:0042327 394 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
response to abiotic stimulus GO:0009628 336 0.028
monocarboxylic acid metabolic process GO:0032787 185 0.028
Mouse
protein modification by small protein conjugation GO:0032446 342 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.028
cerebellum development GO:0021549 2 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
rna processing GO:0006396 255 0.027
regulation of cell differentiation GO:0045595 393 0.027
response to biotic stimulus GO:0009607 276 0.027
negative regulation of developmental process GO:0051093 247 0.027
regulation of cellular component biogenesis GO:0044087 281 0.027
response to organic cyclic compound GO:0014070 204 0.026
actin filament based process GO:0030029 224 0.026
regulation of secretion GO:0051046 194 0.026
regeneration GO:0031099 4 0.026
regulation of transferase activity GO:0051338 355 0.026
positive regulation of cell cycle GO:0045787 140 0.025
cation transport GO:0006812 331 0.025
negative regulation of protein modification process GO:0031400 200 0.025
inorganic ion transmembrane transport GO:0098660 231 0.025
regulation of cellular component movement GO:0051270 334 0.025
segmentation GO:0035282 4 0.024
defense response GO:0006952 315 0.024
chloride transmembrane transport GO:1902476 38 0.024
cellular response to nitrogen compound GO:1901699 144 0.024
lipid metabolic process GO:0006629 381 0.024
protein catabolic process GO:0030163 325 0.024
cellular lipid metabolic process GO:0044255 303 0.024
cell cycle phase transition GO:0044770 173 0.023
regulation of mapk cascade GO:0043408 262 0.023
protein tetramerization GO:0051262 47 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
ras protein signal transduction GO:0007265 73 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
purine nucleoside catabolic process GO:0006152 398 0.022
organelle assembly GO:0070925 176 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
positive regulation of cell proliferation GO:0008284 301 0.021
positive regulation of immune system process GO:0002684 283 0.021
nervous system development GO:0007399 293 0.021
Mouse
secretion by cell GO:0032940 226 0.021
cell adhesion GO:0007155 325 0.021
cytoplasmic transport GO:0016482 379 0.021
protein ubiquitination GO:0016567 314 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
response to acid chemical GO:0001101 66 0.020
regulation of cell motility GO:2000145 299 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
regulation of proteolysis GO:0030162 293 0.020
neuromuscular junction development GO:0007528 3 0.020
cellular response to lipid GO:0071396 127 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
vitamin metabolic process GO:0006766 26 0.020
regulation of locomotion GO:0040012 329 0.020
purine containing compound catabolic process GO:0072523 411 0.020
pigment biosynthetic process GO:0046148 10 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
protein maturation GO:0051604 233 0.020
protein acetylation GO:0006473 116 0.020
multicellular organismal aging GO:0010259 3 0.020
ribonucleoside catabolic process GO:0042454 406 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
determination of adult lifespan GO:0008340 2 0.019
immune response GO:0006955 307 0.019
positive regulation of developmental process GO:0051094 314 0.019
modified amino acid transport GO:0072337 11 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
organic acid transport GO:0015849 65 0.019
innate immune response GO:0045087 178 0.019
regulation of protein complex assembly GO:0043254 147 0.019
single organism cellular localization GO:1902580 332 0.019
organophosphate catabolic process GO:0046434 430 0.019
response to peptide hormone GO:0043434 61 0.019
response to other organism GO:0051707 261 0.019
biological adhesion GO:0022610 331 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
membrane organization GO:0061024 292 0.019
secretion GO:0046903 254 0.019
rho protein signal transduction GO:0007266 26 0.019
single organism membrane organization GO:0044802 268 0.018
protein acylation GO:0043543 138 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
positive regulation of transferase activity GO:0051347 227 0.018
hindbrain development GO:0030902 3 0.018
positive regulation of catabolic process GO:0009896 310 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
regulation of peptide secretion GO:0002791 42 0.018
cellular protein catabolic process GO:0044257 261 0.018
cell morphogenesis GO:0000902 296 0.018
ncrna processing GO:0034470 83 0.018
growth GO:0040007 202 0.018
positive regulation of secretion GO:0051047 116 0.018
cellular component morphogenesis GO:0032989 314 0.018
locomotory behavior GO:0007626 1 0.018
organic anion transport GO:0015711 103 0.018
memory GO:0007613 3 0.018
regulation of cellular response to stress GO:0080135 244 0.018
atp metabolic process GO:0046034 176 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
compound eye development GO:0048749 1 0.018
protein processing GO:0016485 226 0.018
cellular homeostasis GO:0019725 196 0.017
cardiovascular system development GO:0072358 262 0.017
positive regulation of cell death GO:0010942 263 0.017
response to hormone GO:0009725 175 0.017
regulation of cell migration GO:0030334 289 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
cation transmembrane transport GO:0098655 238 0.017
patterning of blood vessels GO:0001569 2 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
monocarboxylic acid biosynthetic process GO:0072330 67 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
regulation of establishment of protein localization GO:0070201 242 0.017
cell projection organization GO:0030030 252 0.017
Mouse
dephosphorylation GO:0016311 209 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
negative regulation of cell cycle GO:0045786 193 0.017
cellular amino acid biosynthetic process GO:0008652 30 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
anion transmembrane transport GO:0098656 76 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
blastoderm segmentation GO:0007350 2 0.017
regulation of protein localization GO:0032880 296 0.017
circulatory system development GO:0072359 262 0.017
nucleotide catabolic process GO:0009166 408 0.017
intracellular protein transport GO:0006886 270 0.016
regulation of cytokine production GO:0001817 232 0.016
chromatin organization GO:0006325 351 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
neurological system process GO:0050877 163 0.016
morphogenesis of a polarized epithelium GO:0001738 3 0.016
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.016
regulation of cell growth GO:0001558 135 0.016
amino acid activation GO:0043038 12 0.016
vesicle mediated transport GO:0016192 371 0.016
negative regulation of cell migration GO:0030336 102 0.016
response to insulin GO:0032868 45 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
regulation of growth GO:0040008 165 0.016
hexose metabolic process GO:0019318 55 0.016
negative regulation of cell cycle process GO:0010948 121 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
cellular protein complex assembly GO:0043623 188 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
catagen GO:0042637 3 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
oocyte development GO:0048599 1 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
chloride transport GO:0006821 41 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
amide transport GO:0042886 76 0.015
purine containing compound biosynthetic process GO:0072522 88 0.015
epithelium development GO:0060429 227 0.015
Mouse
positive regulation of kinase activity GO:0033674 204 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
neuron apoptotic process GO:0051402 39 0.015
head development GO:0060322 108 0.015
regulation of response to external stimulus GO:0032101 222 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
regulation of secretion by cell GO:1903530 177 0.015
regulation of peptide transport GO:0090087 62 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
regulation of immune response GO:0050776 201 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
response to oxidative stress GO:0006979 121 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.015
salivary gland morphogenesis GO:0007435 4 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
oocyte differentiation GO:0009994 2 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
actin cytoskeleton organization GO:0030036 207 0.015
cell growth GO:0016049 160 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
internal protein amino acid acetylation GO:0006475 101 0.015
response to bacterium GO:0009617 144 0.015
signal release GO:0023061 70 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
cardiac muscle cell contraction GO:0086003 4 0.014
cellular chemical homeostasis GO:0055082 180 0.014
protein homooligomerization GO:0051260 100 0.014
microtubule based process GO:0007017 210 0.014
regulation of protein transport GO:0051223 213 0.014
regulation of multi organism process GO:0043900 157 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
serine family amino acid catabolic process GO:0009071 5 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
regulation of binding GO:0051098 111 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
rhythmic behavior GO:0007622 2 0.014
regulation of intracellular transport GO:0032386 195 0.014
peptide transport GO:0015833 74 0.014
somatic stem cell maintenance GO:0035019 4 0.014
cellular amide metabolic process GO:0043603 69 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
pharynx development GO:0060465 1 0.014
nucleoside catabolic process GO:0009164 408 0.014
sulfur compound metabolic process GO:0006790 101 0.014
Mouse
response to growth factor GO:0070848 205 0.014
hormone transport GO:0009914 68 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
blood vessel morphogenesis GO:0048514 162 0.014
spermatid differentiation GO:0048515 4 0.014
cell activation GO:0001775 213 0.014
pyruvate metabolic process GO:0006090 26 0.014
negative regulation of cell motility GO:2000146 104 0.014
response to steroid hormone GO:0048545 80 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
negative regulation of transferase activity GO:0051348 124 0.014
negative regulation of protein maturation GO:1903318 142 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
protein localization to organelle GO:0033365 280 0.014
hormone secretion GO:0046879 65 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
canonical wnt signaling pathway GO:0060070 116 0.013
inner ear morphogenesis GO:0042472 4 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
alpha amino acid biosynthetic process GO:1901607 23 0.013
peripheral nervous system development GO:0007422 2 0.013
regulation of protein maturation GO:1903317 150 0.013
wnt signaling pathway GO:0016055 156 0.013
negative regulation of cellular component movement GO:0051271 106 0.013
neuron development GO:0048666 113 0.013
Mouse
epidermis development GO:0008544 59 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
motor neuron axon guidance GO:0008045 2 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
brain development GO:0007420 97 0.013
ion homeostasis GO:0050801 230 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.013
oxidoreduction coenzyme metabolic process GO:0006733 19 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
neurotransmitter secretion GO:0007269 4 0.013
negative regulation of protein processing GO:0010955 142 0.013
response to radiation GO:0009314 151 0.013
positive regulation of cellular protein catabolic process GO:1903364 37 0.013
single organism cell adhesion GO:0098602 179 0.013
cell division GO:0051301 168 0.013
positive regulation of organelle organization GO:0010638 195 0.013
cell fate determination GO:0001709 3 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
peptide secretion GO:0002790 51 0.013
negative regulation of protein complex assembly GO:0031333 43 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
negative regulation of organelle organization GO:0010639 126 0.012
adult locomotory behavior GO:0008344 1 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
striated muscle contraction GO:0006941 52 0.012
positive regulation of immune response GO:0050778 159 0.012
tripartite regional subdivision GO:0007351 2 0.012
epithelial cell differentiation GO:0030855 141 0.012
cell projection assembly GO:0030031 126 0.012
regulation of cell adhesion GO:0030155 166 0.012
negative regulation of cytokine production GO:0001818 82 0.012
anterior posterior axis specification GO:0009948 2 0.012
endocytosis GO:0006897 159 0.012
metencephalon development GO:0022037 2 0.012
metal ion transport GO:0030001 272 0.012
positive regulation of mitotic cell cycle GO:0045931 60 0.012
vasculature development GO:0001944 181 0.012
tissue regeneration GO:0042246 3 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
spermatid development GO:0007286 4 0.012
negative regulation of response to external stimulus GO:0032102 83 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
cardiac muscle contraction GO:0060048 34 0.012
circadian behavior GO:0048512 2 0.012
regulation of neuron death GO:1901214 56 0.012
response to axon injury GO:0048678 1 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
generation of neurons GO:0048699 152 0.012
Mouse
carboxylic acid transport GO:0046942 63 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
regulation of protein processing GO:0070613 150 0.012
fatty acid metabolic process GO:0006631 115 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.012
forebrain neuron differentiation GO:0021879 3 0.012
positive regulation of protein transport GO:0051222 135 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
regulation of translation GO:0006417 89 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
neuroblast proliferation GO:0007405 4 0.012
cellular response to organonitrogen compound GO:0071417 124 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
regulation of mitosis GO:0007088 63 0.012
hemopoiesis GO:0030097 180 0.012
regulation of cell development GO:0060284 161 0.012
negative regulation of locomotion GO:0040013 118 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
regulation of peptidase activity GO:0052547 180 0.012
ribonucleotide biosynthetic process GO:0009260 81 0.012
endomembrane system organization GO:0010256 196 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
reproductive process GO:0022414 106 0.012
regulation of defense response GO:0031347 154 0.012
regulation of insulin secretion GO:0050796 33 0.011
nuclear transport GO:0051169 179 0.011
response to metal ion GO:0010038 84 0.011
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.011
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
meiosis i GO:0007127 4 0.011
cysteine metabolic process GO:0006534 4 0.011
translation GO:0006412 132 0.011
limbic system development GO:0021761 3 0.011
positive regulation of proteolysis GO:0045862 142 0.011
peptide hormone secretion GO:0030072 50 0.011
anion transport GO:0006820 161 0.011
epidermis morphogenesis GO:0048730 3 0.011
response to fungus GO:0009620 4 0.011
epithelial cell migration GO:0010631 119 0.011
organelle fission GO:0048285 149 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
regulation of gtpase activity GO:0043087 180 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
cap independent translational initiation GO:0002190 4 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
cerebellar cortex development GO:0021695 1 0.011
organ formation GO:0048645 3 0.011
rna interference GO:0016246 4 0.011
response to lipopolysaccharide GO:0032496 70 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of cell division GO:0051302 116 0.011
mitotic nuclear division GO:0007067 119 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
positive regulation of cell development GO:0010720 92 0.011
negative regulation of kinase activity GO:0033673 106 0.011
muscle contraction GO:0006936 73 0.011
protein targeting GO:0006605 187 0.011
forebrain generation of neurons GO:0021872 3 0.011
developmental programmed cell death GO:0010623 3 0.011
macromolecule methylation GO:0043414 97 0.011
chemotaxis GO:0006935 157 0.011
axon cargo transport GO:0008088 2 0.011
negative regulation of cell fate commitment GO:0010454 3 0.011
glial cell migration GO:0008347 4 0.011
alanine transport GO:0032328 3 0.011
response to cytokine GO:0034097 232 0.011
maintenance of location GO:0051235 112 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
regulation of peptide hormone secretion GO:0090276 41 0.011
positive regulation of neural precursor cell proliferation GO:2000179 2 0.011
l amino acid import GO:0043092 4 0.011
blood vessel development GO:0001568 172 0.011
stress activated mapk cascade GO:0051403 93 0.011
actin mediated cell contraction GO:0070252 12 0.011
single organismal cell cell adhesion GO:0016337 148 0.011
cell projection morphogenesis GO:0048858 129 0.011
phospholipid metabolic process GO:0006644 99 0.011
establishment of planar polarity GO:0001736 3 0.010
regulation of vesicle mediated transport GO:0060627 130 0.010
sulfur compound catabolic process GO:0044273 8 0.010
regulation of mitotic cell cycle phase transition GO:1901990 118 0.010
angiogenesis GO:0001525 147 0.010
gtp catabolic process GO:0006184 237 0.010
retinal ganglion cell axon guidance GO:0031290 2 0.010
positive regulation of synaptic transmission GO:0050806 4 0.010
nadh metabolic process GO:0006734 1 0.010
muscle system process GO:0003012 81 0.010
establishment of tissue polarity GO:0007164 3 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010
neural tube formation GO:0001841 3 0.010
response to inorganic substance GO:0010035 127 0.010
cell part morphogenesis GO:0032990 137 0.010
ameboidal type cell migration GO:0001667 135 0.010

PHGDH disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.240
amino acid metabolic disorder DOID:9252 50 0.240
inherited metabolic disorder DOID:655 242 0.240
nervous system disease DOID:863 431 0.029
neuropathy DOID:870 52 0.029
central nervous system disease DOID:331 186 0.026
sensory system disease DOID:0050155 203 0.023
eye and adnexa disease DOID:1492 150 0.023
eye disease DOID:5614 149 0.023
musculoskeletal system disease DOID:17 223 0.020
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
organ system cancer DOID:0050686 164 0.018
connective tissue disease DOID:65 109 0.017
bone disease DOID:0080001 88 0.014
retinal disease DOID:5679 118 0.014
immune system disease DOID:2914 155 0.011
neuromuscular disease DOID:440 38 0.011
charcot marie tooth disease DOID:10595 33 0.011
carbohydrate metabolic disorder DOID:2978 55 0.011