Homo sapiens

50 known processes

PIK3C3

phosphoinositide-3-kinase, class 3

(Aliases: hVps34,VPS34,MGC61518)

PIK3C3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vacuole organization GO:0007033 44 0.795
Rat
cytoplasmic transport GO:0016482 379 0.526
autophagy GO:0006914 88 0.496
Yeast Rat
endosomal transport GO:0016197 129 0.467
cellular response to external stimulus GO:0071496 111 0.456
Rat
cellular response to starvation GO:0009267 58 0.403
Rat
endosome to lysosome transport GO:0008333 21 0.310
positive regulation of catabolic process GO:0009896 310 0.265
response to starvation GO:0042594 59 0.220
Rat
purine containing compound catabolic process GO:0072523 411 0.198
ribonucleotide catabolic process GO:0009261 405 0.181
vacuolar transport GO:0007034 34 0.174
glycosyl compound catabolic process GO:1901658 413 0.170
gtp metabolic process GO:0046039 239 0.167
vesicle mediated transport GO:0016192 371 0.158
small gtpase mediated signal transduction GO:0007264 78 0.139
gtp catabolic process GO:0006184 237 0.138
purine ribonucleotide catabolic process GO:0009154 404 0.135
purine nucleoside triphosphate catabolic process GO:0009146 392 0.128
nucleotide catabolic process GO:0009166 408 0.127
purine nucleotide catabolic process GO:0006195 405 0.120
regulation of nucleoside metabolic process GO:0009118 209 0.117
nucleoside triphosphate catabolic process GO:0009143 394 0.116
response to nutrient levels GO:0031667 81 0.115
Rat
organophosphate catabolic process GO:0046434 430 0.109
nucleoside triphosphate metabolic process GO:0009141 422 0.107
cellular response to nutrient levels GO:0031669 69 0.106
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.104
determination of adult lifespan GO:0008340 2 0.099
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.098
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.096
positive regulation of cellular component organization GO:0051130 376 0.095
regulation of gtpase activity GO:0043087 180 0.094
positive regulation of nucleotide metabolic process GO:0045981 230 0.093
purine nucleoside catabolic process GO:0006152 398 0.090
positive regulation of cellular catabolic process GO:0031331 284 0.090
macroautophagy GO:0016236 39 0.090
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.086
multicellular organismal aging GO:0010259 3 0.085
cell adhesion GO:0007155 325 0.085
regulation of nucleotide catabolic process GO:0030811 205 0.083
nucleoside catabolic process GO:0009164 408 0.082
ribonucleoside catabolic process GO:0042454 406 0.082
regulation of cellular component biogenesis GO:0044087 281 0.081
regulation of gtp catabolic process GO:0033124 180 0.080
purine ribonucleoside catabolic process GO:0046130 398 0.077
guanosine containing compound catabolic process GO:1901069 239 0.076
regulation of purine nucleotide metabolic process GO:1900542 264 0.073
regulation of purine nucleotide catabolic process GO:0033121 205 0.066
post embryonic development GO:0009791 2 0.064
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.063
ras protein signal transduction GO:0007265 73 0.063
intracellular protein transport GO:0006886 270 0.062
regulation of locomotion GO:0040012 329 0.061
enzyme linked receptor protein signaling pathway GO:0007167 303 0.060
nucleoside phosphate catabolic process GO:1901292 412 0.060
ribonucleoside triphosphate catabolic process GO:0009203 391 0.057
regulation of cytoskeleton organization GO:0051493 177 0.056
positive regulation of gtp catabolic process GO:0033126 166 0.053
cellular amine metabolic process GO:0044106 41 0.052
cellular macromolecule catabolic process GO:0044265 380 0.051
response to other organism GO:0051707 261 0.051
purine nucleoside triphosphate metabolic process GO:0009144 412 0.051
autophagic vacuole assembly GO:0000045 19 0.050
Rat
purine ribonucleoside metabolic process GO:0046128 437 0.050
cellular protein catabolic process GO:0044257 261 0.049
regulation of protein localization GO:0032880 296 0.049
Rat
regulation of ras gtpase activity GO:0032318 128 0.048
regulation of cell motility GO:2000145 299 0.046
amine metabolic process GO:0009308 44 0.046
regulation of nucleotide metabolic process GO:0006140 269 0.044
single organism cellular localization GO:1902580 332 0.044
secretion GO:0046903 254 0.044
Rat
regulation of cellular response to stress GO:0080135 244 0.044
positive regulation of nucleoside metabolic process GO:0045979 186 0.043
lipid metabolic process GO:0006629 381 0.043
biological adhesion GO:0022610 331 0.042
negative regulation of cellular component organization GO:0051129 235 0.042
negative regulation of protein metabolic process GO:0051248 391 0.042
growth GO:0040007 202 0.041
guanosine containing compound metabolic process GO:1901068 244 0.039
positive regulation of cellular amine metabolic process GO:0033240 7 0.039
response to external biotic stimulus GO:0043207 261 0.039
rho protein signal transduction GO:0007266 26 0.039
positive regulation of nucleotide catabolic process GO:0030813 185 0.039
protein catabolic process GO:0030163 325 0.039
regulation of growth GO:0040008 165 0.038
response to biotic stimulus GO:0009607 276 0.038
regulation of cellular ketone metabolic process GO:0010565 50 0.037
regulation of autophagy GO:0010506 52 0.037
cation transport GO:0006812 331 0.036
oogenesis GO:0048477 2 0.036
cellular response to endogenous stimulus GO:0071495 336 0.036
regulation of cell migration GO:0030334 289 0.035
cellular amino acid metabolic process GO:0006520 116 0.035
positive regulation of autophagy GO:0010508 24 0.035
negative regulation of developmental process GO:0051093 247 0.034
establishment of protein localization to organelle GO:0072594 172 0.034
positive regulation of transport GO:0051050 336 0.034
cell substrate adhesion GO:0031589 132 0.033
regulation of response to external stimulus GO:0032101 222 0.033
neuromuscular junction development GO:0007528 3 0.032
positive regulation of cellular component biogenesis GO:0044089 158 0.032
apoptotic signaling pathway GO:0097190 268 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
cellular macromolecular complex assembly GO:0034622 324 0.032
positive regulation of hydrolase activity GO:0051345 331 0.032
negative regulation of cell proliferation GO:0008285 228 0.032
cell morphogenesis GO:0000902 296 0.031
lytic vacuole organization GO:0080171 24 0.031
defense response GO:0006952 315 0.030
positive regulation of gtpase activity GO:0043547 166 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.029
organelle assembly GO:0070925 176 0.029
Rat
regulation of ras protein signal transduction GO:0046578 155 0.028
protein targeting GO:0006605 187 0.028
cellular ketone metabolic process GO:0042180 80 0.028
positive regulation of phosphorylation GO:0042327 394 0.027
mitotic cell cycle GO:0000278 326 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
cellular component morphogenesis GO:0032989 314 0.027
nervous system development GO:0007399 293 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.026
protein localization to organelle GO:0033365 280 0.026
response to oxygen containing compound GO:1901700 369 0.026
Rat
response to extracellular stimulus GO:0009991 85 0.026
Rat
negative regulation of catalytic activity GO:0043086 335 0.026
regulation of protein kinase activity GO:0045859 289 0.026
regulation of cell morphogenesis GO:0022604 153 0.025
locomotory behavior GO:0007626 1 0.025
regulation of intracellular transport GO:0032386 195 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.024
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
purine nucleoside monophosphate metabolic process GO:0009126 186 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
positive regulation of immune system process GO:0002684 283 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.024
regulation of actin filament based process GO:0032970 141 0.023
cellular response to extracellular stimulus GO:0031668 72 0.023
Rat
maintenance of location in cell GO:0051651 62 0.023
maintenance of location GO:0051235 112 0.023
endomembrane system organization GO:0010256 196 0.023
Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.023
cell projection morphogenesis GO:0048858 129 0.022
positive regulation of developmental process GO:0051094 314 0.022
rna splicing GO:0008380 131 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
actin filament based process GO:0030029 224 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
multi organism cellular process GO:0044764 156 0.022
regulation of rho protein signal transduction GO:0035023 79 0.022
innate immune response GO:0045087 178 0.022
late endosome to vacuole transport GO:0045324 2 0.022
positive regulation of protein transport GO:0051222 135 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
regulation of cell adhesion GO:0030155 166 0.021
negative regulation of apoptotic process GO:0043066 316 0.021
negative regulation of growth GO:0045926 97 0.020
positive regulation of organelle organization GO:0010638 195 0.020
negative regulation of cell development GO:0010721 48 0.020
single organism membrane organization GO:0044802 268 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
positive regulation of dna templated transcription elongation GO:0032786 18 0.020
Yeast
regulation of cellular component movement GO:0051270 334 0.020
regulation of vesicle mediated transport GO:0060627 130 0.020
negative regulation of cell cycle GO:0045786 193 0.019
regulation of transferase activity GO:0051338 355 0.019
cell growth GO:0016049 160 0.019
response to endoplasmic reticulum stress GO:0034976 49 0.019
neuron differentiation GO:0030182 138 0.019
oocyte differentiation GO:0009994 2 0.019
golgi vesicle transport GO:0048193 80 0.019
metal ion transport GO:0030001 272 0.019
negative regulation of cell migration GO:0030336 102 0.019
response to cytokine GO:0034097 232 0.019
negative regulation of cell motility GO:2000146 104 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
protein modification by small protein conjugation GO:0032446 342 0.018
regulation of neural precursor cell proliferation GO:2000177 4 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
regulation of protein complex assembly GO:0043254 147 0.018
negative regulation of locomotion GO:0040013 118 0.018
regulation of small gtpase mediated signal transduction GO:0051056 156 0.018
regulation of cell cycle GO:0051726 393 0.018
regulation of cellular protein catabolic process GO:1903362 96 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
response to growth factor GO:0070848 205 0.017
cell division GO:0051301 168 0.017
protein ubiquitination GO:0016567 314 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
maintenance of protein location GO:0045185 57 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
response to abiotic stimulus GO:0009628 336 0.017
atp metabolic process GO:0046034 176 0.017
cellular lipid metabolic process GO:0044255 303 0.017
negative regulation of protein modification process GO:0031400 200 0.017
regulation of cell growth GO:0001558 135 0.017
membrane organization GO:0061024 292 0.017
negative regulation of transport GO:0051051 176 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.017
negative regulation of cellular component movement GO:0051271 106 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
cellular response to organonitrogen compound GO:0071417 124 0.016
circulatory system development GO:0072359 262 0.016
associative learning GO:0008306 1 0.016
chromatin modification GO:0016568 298 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
ameboidal type cell migration GO:0001667 135 0.016
positive regulation of ras gtpase activity GO:0032320 117 0.016
positive regulation of transferase activity GO:0051347 227 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
positive regulation of protein catabolic process GO:0045732 75 0.016
oocyte development GO:0048599 1 0.016
mitotic cell cycle process GO:1903047 286 0.016
regulation of protein catabolic process GO:0042176 155 0.016
immune response GO:0006955 307 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
cell projection organization GO:0030030 252 0.015
regulation of ion transport GO:0043269 189 0.015
negative regulation of catabolic process GO:0009895 104 0.015
negative regulation of cellular catabolic process GO:0031330 83 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
single organism cell adhesion GO:0098602 179 0.015
female gamete generation GO:0007292 2 0.015
regulation of proteolysis GO:0030162 293 0.015
regulation of tor signaling GO:0032006 30 0.015
system process GO:0003008 349 0.015
viral process GO:0016032 146 0.015
protein localization to membrane GO:0072657 160 0.014
regulation of dna metabolic process GO:0051052 153 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.014
regulation of organelle assembly GO:1902115 40 0.014
cytokinesis GO:0000910 96 0.014
cell part morphogenesis GO:0032990 137 0.014
secretion by cell GO:0032940 226 0.014
Rat
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
limbic system development GO:0021761 3 0.014
receptor metabolic process GO:0043112 81 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
regulation of cellular component size GO:0032535 82 0.014
regulation of protein stability GO:0031647 87 0.014
regulation of rab gtpase activity GO:0032313 39 0.014
spermatid differentiation GO:0048515 4 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
axon cargo transport GO:0008088 2 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
lipid localization GO:0010876 106 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
generation of neurons GO:0048699 152 0.013
neuron development GO:0048666 113 0.013
regulation of feeding behavior GO:0060259 3 0.013
segmentation GO:0035282 4 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
positive regulation of response to external stimulus GO:0032103 88 0.013
cell cycle phase transition GO:0044770 173 0.013
cardiovascular system development GO:0072358 262 0.013
regulation of protein transport GO:0051223 213 0.013
Rat
visual behavior GO:0007632 2 0.013
purine nucleoside monophosphate catabolic process GO:0009128 158 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
cellular component disassembly GO:0022411 92 0.013
response to peptide GO:1901652 65 0.012
plasma membrane organization GO:0007009 115 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
regulation of kinase activity GO:0043549 314 0.012
response to nitrogen compound GO:1901698 184 0.012
Rat
regulation of protein processing GO:0070613 150 0.012
cell development GO:0048468 328 0.012
vesicle organization GO:0016050 62 0.012
negative regulation of integrin activation GO:0033624 2 0.012
positive regulation of cell death GO:0010942 263 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
positive regulation of rab gtpase activity GO:0032851 39 0.012
lipid biosynthetic process GO:0008610 177 0.012
lysosomal transport GO:0007041 33 0.012
protein localization to plasma membrane GO:0072659 93 0.012
vasculature development GO:0001944 181 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
receptor catabolic process GO:0032801 11 0.012
actin cytoskeleton organization GO:0030036 207 0.012
regulation of cell differentiation GO:0045595 393 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
regulation of multi organism process GO:0043900 157 0.012
cellular response to lipid GO:0071396 127 0.012
response to hypoxia GO:0001666 96 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
negative regulation of cell death GO:0060548 345 0.011
peptidyl lysine modification GO:0018205 144 0.011
spermatid development GO:0007286 4 0.011
transmembrane transport GO:0055085 399 0.011
memory GO:0007613 3 0.011
regulation of defense response GO:0031347 154 0.011
endocytosis GO:0006897 159 0.011
retrograde transport endosome to golgi GO:0042147 45 0.011
rab protein signal transduction GO:0032482 4 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
Rat
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
cell projection assembly GO:0030031 126 0.011
regulation of anatomical structure size GO:0090066 101 0.011
rna processing GO:0006396 255 0.011
dna templated transcription elongation GO:0006354 25 0.011
Yeast
neurogenesis GO:0022008 169 0.011
regulation of microtubule based process GO:0032886 74 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
regulation of rab protein signal transduction GO:0032483 39 0.011
microtubule based process GO:0007017 210 0.011
response to acid chemical GO:0001101 66 0.011
Rat
reactive oxygen species biosynthetic process GO:1903409 4 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
somatic stem cell maintenance GO:0035019 4 0.010
exocytosis GO:0006887 71 0.010
protein import into nucleus GO:0006606 104 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.010
positive regulation of proteolysis GO:0045862 142 0.010
response to lipid GO:0033993 206 0.010
inner ear morphogenesis GO:0042472 4 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
regulation of canonical wnt signaling pathway GO:0060828 88 0.010
cellular homeostasis GO:0019725 196 0.010
metencephalon development GO:0022037 2 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.010
protein autophosphorylation GO:0046777 123 0.010
positive regulation of kinase activity GO:0033674 204 0.010
blastoderm segmentation GO:0007350 2 0.010

PIK3C3 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.035
disease of cellular proliferation DOID:14566 174 0.035
organ system cancer DOID:0050686 164 0.028
disease of metabolism DOID:0014667 295 0.016
sensory system disease DOID:0050155 203 0.010
nervous system disease DOID:863 431 0.010