Homo sapiens

0 known processes

PIK3CB

phosphoinositide-3-kinase, catalytic, beta polypeptide

(Aliases: PI3KBETA,PI3K,P110BETA,DKFZp779K1237,MGC133043,PIK3C1)

PIK3CB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.721
post embryonic development GO:0009791 2 0.326
Worm Fly
regulation of cellular component biogenesis GO:0044087 281 0.230
organ formation GO:0048645 3 0.227
single organism cellular localization GO:1902580 332 0.210
lipid metabolic process GO:0006629 381 0.176
Human Mouse Rat Fly
determination of adult lifespan GO:0008340 2 0.163
Worm
cellular lipid metabolic process GO:0044255 303 0.163
Human Mouse Rat Fly
locomotory behavior GO:0007626 1 0.143
regulation of cellular amine metabolic process GO:0033238 11 0.125
oogenesis GO:0048477 2 0.124
Fly
heart field specification GO:0003128 2 0.124
cation transport GO:0006812 331 0.123
glycerolipid metabolic process GO:0046486 107 0.122
Human Mouse Rat Fly
phosphatidylinositol metabolic process GO:0046488 53 0.120
Human Mouse Rat Fly
negative regulation of cell fate specification GO:0009996 3 0.113
cell fate determination GO:0001709 3 0.112
negative regulation of cell fate commitment GO:0010454 3 0.109
regulation of heart induction GO:0090381 2 0.101
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.100
regulation of mapk cascade GO:0043408 262 0.100
heart formation GO:0060914 2 0.096
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.094
lipid modification GO:0030258 84 0.093
Human Mouse Rat Fly
regulation of kinase activity GO:0043549 314 0.092
regulation of protein serine threonine kinase activity GO:0071900 179 0.091
regulation of organ formation GO:0003156 4 0.087
positive regulation of transferase activity GO:0051347 227 0.086
protein localization to organelle GO:0033365 280 0.085
positive regulation of map kinase activity GO:0043406 80 0.083
behavior GO:0007610 112 0.083
Worm Fly
regulation of synaptic plasticity GO:0048167 3 0.083
Fly
actin filament based process GO:0030029 224 0.082
ras protein signal transduction GO:0007265 73 0.081
cell cell signaling GO:0007267 155 0.081
Fly
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 3 0.081
Human Mouse Rat Fly
rho protein signal transduction GO:0007266 26 0.081
regulation of response to external stimulus GO:0032101 222 0.080
Worm
epidermis morphogenesis GO:0048730 3 0.078
positive regulation of jnk cascade GO:0046330 52 0.078
salivary gland morphogenesis GO:0007435 4 0.077
Fly
signal transduction by phosphorylation GO:0023014 297 0.075
single organism membrane organization GO:0044802 268 0.075
jnk cascade GO:0007254 80 0.075
glycerophospholipid metabolic process GO:0006650 84 0.074
Human Mouse Rat Fly
chemotaxis GO:0006935 157 0.074
Worm
multicellular organismal aging GO:0010259 3 0.073
Worm
cellular component morphogenesis GO:0032989 314 0.072
Fly
response to growth factor GO:0070848 205 0.072
morphogenesis of embryonic epithelium GO:0016331 4 0.071
cellular chemical homeostasis GO:0055082 180 0.071
Mouse
mapk cascade GO:0000165 288 0.070
biological adhesion GO:0022610 331 0.070
Mouse
regulation of cell migration GO:0030334 289 0.070
photoreceptor cell differentiation GO:0046530 2 0.069
neuromuscular junction development GO:0007528 3 0.069
Fly
anterior posterior axis specification GO:0009948 2 0.068
negative regulation of protein metabolic process GO:0051248 391 0.067
protein catabolic process GO:0030163 325 0.066
phospholipid metabolic process GO:0006644 99 0.065
Human Mouse Rat Fly
cellular ketone metabolic process GO:0042180 80 0.064
heart induction GO:0003129 4 0.064
growth GO:0040007 202 0.064
Fly
female gamete generation GO:0007292 2 0.064
Fly
cellular macromolecule catabolic process GO:0044265 380 0.063
regulation of jnk cascade GO:0046328 73 0.063
outflow tract septum morphogenesis GO:0003148 4 0.063
positive regulation of mapk cascade GO:0043410 190 0.062
positive regulation of phosphorylation GO:0042327 394 0.062
cytoplasmic transport GO:0016482 379 0.062
metal ion transport GO:0030001 272 0.061
positive regulation of kinase activity GO:0033674 204 0.061
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.061
amine metabolic process GO:0009308 44 0.061
regulation of map kinase activity GO:0043405 108 0.060
spermatid development GO:0007286 4 0.060
associative learning GO:0008306 1 0.059
inner ear morphogenesis GO:0042472 4 0.059
cellular macromolecular complex assembly GO:0034622 324 0.059
positive regulation of transport GO:0051050 336 0.059
positive regulation of developmental process GO:0051094 314 0.058
Fly
startle response GO:0001964 3 0.058
microtubule cytoskeleton organization GO:0000226 176 0.058
blastoderm segmentation GO:0007350 2 0.057
positive regulation of catabolic process GO:0009896 310 0.056
negative regulation of multicellular organismal process GO:0051241 317 0.056
cell division GO:0051301 168 0.055
Mouse
oocyte differentiation GO:0009994 2 0.055
regulation of autophagy GO:0010506 52 0.055
Fly
segmentation GO:0035282 4 0.055
cellular response to dna damage stimulus GO:0006974 379 0.054
regulation of cellular response to stress GO:0080135 244 0.054
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.054
regulation of locomotion GO:0040012 329 0.054
Worm
exocytosis GO:0006887 71 0.054
somatic stem cell maintenance GO:0035019 4 0.054
organ induction GO:0001759 4 0.053
neural tube formation GO:0001841 3 0.052
positive regulation of cellular component organization GO:0051130 376 0.052
cardiac cell fate specification GO:0060912 1 0.051
positive regulation of locomotion GO:0040017 186 0.051
spermatid differentiation GO:0048515 4 0.050
embryonic epithelial tube formation GO:0001838 4 0.050
secretion by cell GO:0032940 226 0.049
intracellular protein transport GO:0006886 270 0.049
mitotic cell cycle GO:0000278 326 0.048
Fly
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.048
regulation of cell cycle GO:0051726 393 0.048
Fly
nervous system development GO:0007399 293 0.047
Fly
cellular response to organic cyclic compound GO:0071407 127 0.047
cellular amino acid metabolic process GO:0006520 116 0.046
defense response GO:0006952 315 0.046
regulation of stress activated mapk cascade GO:0032872 84 0.046
regulation of actin filament based process GO:0032970 141 0.045
regulation of protein localization GO:0032880 296 0.045
system process GO:0003008 349 0.044
Worm
regulation of cardioblast differentiation GO:0051890 4 0.043
negative regulation of apoptotic process GO:0043066 316 0.043
Human
regulation of transferase activity GO:0051338 355 0.042
cellular protein complex assembly GO:0043623 188 0.042
response to other organism GO:0051707 261 0.042
regulation of cellular component movement GO:0051270 334 0.042
carbohydrate metabolic process GO:0005975 207 0.042
Fly
actin filament organization GO:0007015 128 0.041
positive regulation of cellular amine metabolic process GO:0033240 7 0.041
cell fate commitment involved in pattern specification GO:0060581 1 0.041
negative regulation of programmed cell death GO:0043069 321 0.041
Human
chemical homeostasis GO:0048878 306 0.040
Mouse
response to external biotic stimulus GO:0043207 261 0.040
neurological system process GO:0050877 163 0.040
Worm
response to inorganic substance GO:0010035 127 0.040
Worm
negative regulation of catalytic activity GO:0043086 335 0.040
cation homeostasis GO:0055080 189 0.039
Mouse
actin cytoskeleton organization GO:0030036 207 0.039
organ morphogenesis GO:0009887 147 0.039
Fly
circulatory system development GO:0072359 262 0.039
cellular amine metabolic process GO:0044106 41 0.039
leukocyte activation GO:0045321 164 0.039
positive regulation of protein phosphorylation GO:0001934 313 0.039
negative regulation of developmental process GO:0051093 247 0.039
retinal ganglion cell axon guidance GO:0031290 2 0.039
protein localization to nucleus GO:0034504 136 0.038
single organism cell adhesion GO:0098602 179 0.038
specification of organ identity GO:0010092 3 0.038
cardiovascular system development GO:0072358 262 0.038
organelle localization GO:0051640 84 0.038
tissue migration GO:0090130 119 0.038
cranial nerve development GO:0021545 4 0.037
regulation of purine nucleotide catabolic process GO:0033121 205 0.037
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
wnt signaling pathway GO:0016055 156 0.036
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.036
anterior posterior axis specification embryo GO:0008595 2 0.036
motor neuron axon guidance GO:0008045 2 0.036
immune system development GO:0002520 195 0.036
organophosphate catabolic process GO:0046434 430 0.036
negative regulation of cell death GO:0060548 345 0.036
Human
phosphatidylinositol mediated signaling GO:0048015 55 0.036
positive regulation of cell proliferation GO:0008284 301 0.036
activation of protein kinase activity GO:0032147 90 0.035
positive regulation of wnt signaling pathway GO:0030177 54 0.035
regulation of establishment of protein localization GO:0070201 242 0.035
positive regulation of stress activated mapk cascade GO:0032874 60 0.035
coagulation GO:0050817 78 0.035
Mouse
vesicle mediated transport GO:0016192 371 0.035
nucleotide catabolic process GO:0009166 408 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
regulation of immune response GO:0050776 201 0.034
modification dependent macromolecule catabolic process GO:0043632 212 0.034
regulation of cell adhesion GO:0030155 166 0.034
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.034
cell development GO:0048468 328 0.033
Fly
nuclear transport GO:0051169 179 0.033
membrane organization GO:0061024 292 0.033
regulation of transmembrane transport GO:0034762 139 0.033
cardioblast cell fate commitment GO:0042684 1 0.033
cellular response to nitrogen compound GO:1901699 144 0.033
vegf activated platelet derived growth factor receptor signaling pathway GO:0038086 3 0.033
ribonucleotide catabolic process GO:0009261 405 0.033
protein targeting GO:0006605 187 0.032
innate immune response GO:0045087 178 0.032
generation of neurons GO:0048699 152 0.032
Fly
signal release GO:0023061 70 0.032
cellular divalent inorganic cation homeostasis GO:0072503 128 0.032
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.032
establishment of protein localization to organelle GO:0072594 172 0.032
cellular homeostasis GO:0019725 196 0.032
Mouse
cell activation GO:0001775 213 0.032
Mouse
regulation of cell motility GO:2000145 299 0.031
single organism nuclear import GO:1902593 104 0.031
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.031
cellular metal ion homeostasis GO:0006875 146 0.031
Mouse
cell morphogenesis GO:0000902 296 0.031
Fly
epithelial cell differentiation GO:0030855 141 0.031
reactive oxygen species biosynthetic process GO:1903409 4 0.031
mast cell degranulation GO:0043303 4 0.031
regulation of behavior GO:0050795 82 0.031
Worm
regulation of small gtpase mediated signal transduction GO:0051056 156 0.031
regulation of secretion by cell GO:1903530 177 0.031
hematopoietic or lymphoid organ development GO:0048534 186 0.030
regulation of cytokine production GO:0001817 232 0.030
regulation of cellular ketone metabolic process GO:0010565 50 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
maintenance of location GO:0051235 112 0.030
establishment of organelle localization GO:0051656 59 0.030
regulation of neurotransmitter secretion GO:0046928 3 0.030
response to oxygen containing compound GO:1901700 369 0.030
mitotic cell cycle process GO:1903047 286 0.030
endodermal cell fate commitment GO:0001711 4 0.030
cellular ion homeostasis GO:0006873 168 0.030
Mouse
regulation of protein binding GO:0043393 66 0.029
regulation of mitotic cell cycle GO:0007346 189 0.029
Fly
cellular protein catabolic process GO:0044257 261 0.029
regulation of neuronal synaptic plasticity GO:0048168 1 0.029
Fly
regulation of cytoskeleton organization GO:0051493 177 0.029
anatomical structure formation involved in morphogenesis GO:0048646 284 0.029
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.029
microtubule based process GO:0007017 210 0.029
positive regulation of immune system process GO:0002684 283 0.029
regulation of cell development GO:0060284 161 0.029
Fly
oocyte development GO:0048599 1 0.029
positive regulation of cell motility GO:2000147 177 0.029
response to oxidative stress GO:0006979 121 0.029
Worm Fly
response to biotic stimulus GO:0009607 276 0.029
regulation of erk1 and erk2 cascade GO:0070372 99 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.028
negative regulation of cell proliferation GO:0008285 228 0.028
visual behavior GO:0007632 2 0.028
nerve development GO:0021675 4 0.028
calcium ion homeostasis GO:0055074 122 0.028
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.028
Fly
muscle contraction GO:0006936 73 0.028
cell morphogenesis involved in differentiation GO:0000904 144 0.028
Fly
regulation of protein kinase activity GO:0045859 289 0.028
peptidyl serine phosphorylation GO:0018105 101 0.027
g protein coupled receptor signaling pathway GO:0007186 207 0.027
establishment of nucleus localization GO:0040023 1 0.027
epithelium development GO:0060429 227 0.027
protein processing GO:0016485 226 0.027
ubiquitin dependent protein catabolic process GO:0006511 206 0.027
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.027
positive regulation of protein kinase activity GO:0045860 190 0.027
regulation of proteolysis GO:0030162 293 0.027
establishment of planar polarity GO:0001736 3 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
negative regulation of protein phosphorylation GO:0001933 140 0.026
negative regulation of catabolic process GO:0009895 104 0.026
Fly
guanosine containing compound metabolic process GO:1901068 244 0.026
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
erk1 and erk2 cascade GO:0070371 104 0.026
regulation of membrane potential GO:0042391 95 0.026
divalent inorganic cation homeostasis GO:0072507 136 0.026
Mouse
organophosphate biosynthetic process GO:0090407 163 0.026
Human Mouse Rat Fly
tube development GO:0035295 125 0.025
positive regulation of secretion GO:0051047 116 0.025
transmembrane transport GO:0055085 399 0.025
neurotransmitter secretion GO:0007269 4 0.025
cellular calcium ion homeostasis GO:0006874 117 0.025
Mouse
regulation of cell activation GO:0050865 125 0.025
positive regulation of cellular component movement GO:0051272 181 0.025
tripartite regional subdivision GO:0007351 2 0.025
potassium ion transport GO:0006813 62 0.025
purine nucleotide catabolic process GO:0006195 405 0.025
primary neural tube formation GO:0014020 3 0.025
protein maturation GO:0051604 233 0.025
protein localization to membrane GO:0072657 160 0.025
stem cell division GO:0017145 2 0.024
regulation of multi organism process GO:0043900 157 0.024
sensory perception of pain GO:0019233 4 0.024
regulation of heart morphogenesis GO:2000826 4 0.024
negative regulation of cell differentiation GO:0045596 171 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
regulation of ion transport GO:0043269 189 0.024
cytokine production GO:0001816 247 0.024
regulation of protein transport GO:0051223 213 0.024
response to nitrogen compound GO:1901698 184 0.024
establishment of apical basal cell polarity GO:0035089 1 0.024
neurogenesis GO:0022008 169 0.024
Fly
lipid transport GO:0006869 90 0.024
muscle system process GO:0003012 81 0.024
endodermal cell fate specification GO:0001714 4 0.024
apoptotic signaling pathway GO:0097190 268 0.024
metal ion homeostasis GO:0055065 169 0.024
Mouse
cell growth GO:0016049 160 0.024
nucleocytoplasmic transport GO:0006913 176 0.023
regulation of canonical wnt signaling pathway GO:0060828 88 0.023
regulation of intracellular transport GO:0032386 195 0.023
single organism carbohydrate metabolic process GO:0044723 193 0.023
regulation of cardioblast cell fate specification GO:0042686 1 0.023
monovalent inorganic cation transport GO:0015672 128 0.023
positive regulation of protein kinase b signaling GO:0051897 42 0.023
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.023
regulation of dna metabolic process GO:0051052 153 0.023
cell chemotaxis GO:0060326 112 0.022
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 1 0.022
nucleus localization GO:0051647 1 0.022
positive regulation of cell death GO:0010942 263 0.022
blood coagulation GO:0007596 76 0.022
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
positive regulation of response to external stimulus GO:0032103 88 0.022
phospholipid biosynthetic process GO:0008654 44 0.022
Human Mouse Rat Fly
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.022
regulation of cell cycle process GO:0010564 266 0.022
meiotic chromosome segregation GO:0045132 4 0.022
lipid catabolic process GO:0016042 84 0.022
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.022
canonical wnt signaling pathway GO:0060070 116 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
cochlea development GO:0090102 1 0.022
regulation of exocytosis GO:0017157 46 0.021
regulation of secretion GO:0051046 194 0.021
cellular component assembly involved in morphogenesis GO:0010927 73 0.021
cell projection assembly GO:0030031 126 0.021
establishment of monopolar cell polarity GO:0061162 1 0.021
cell part morphogenesis GO:0032990 137 0.021
Fly
regulation of protein import into nucleus GO:0042306 78 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
establishment or maintenance of monopolar cell polarity GO:0061339 1 0.021
aging GO:0007568 66 0.021
Worm
stress activated protein kinase signaling cascade GO:0031098 94 0.021
notch signaling pathway GO:0007219 31 0.021
positive regulation of secretion by cell GO:1903532 108 0.021
cell type specific apoptotic process GO:0097285 125 0.021
stress activated mapk cascade GO:0051403 93 0.021
reproductive process GO:0022414 106 0.021
Fly
cell projection organization GO:0030030 252 0.021
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.021
response to extracellular stimulus GO:0009991 85 0.021
Fly
rhythmic behavior GO:0007622 2 0.020
positive regulation of jun kinase activity GO:0043507 23 0.020
dephosphorylation GO:0016311 209 0.020
regulation of growth GO:0040008 165 0.020
Fly
ion homeostasis GO:0050801 230 0.020
Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
immune effector process GO:0002252 159 0.020
secretion GO:0046903 254 0.020
mitochondrion organization GO:0007005 156 0.020
single organism reproductive process GO:0044702 98 0.020
Fly
regulation of wnt signaling pathway GO:0030111 123 0.020
protein import into nucleus GO:0006606 104 0.020
positive regulation of synaptic transmission GO:0050806 4 0.020
positive regulation of cellular component biogenesis GO:0044089 158 0.020
neuron differentiation GO:0030182 138 0.020
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.020
regulation of protein localization to nucleus GO:1900180 85 0.020
inositol lipid mediated signaling GO:0048017 55 0.020
cellular cation homeostasis GO:0030003 163 0.019
Mouse
blood vessel development GO:0001568 172 0.019
sensory perception GO:0007600 103 0.019
negative regulation of transport GO:0051051 176 0.019
somatic stem cell division GO:0048103 1 0.019
gtp catabolic process GO:0006184 237 0.019
ribonucleoside catabolic process GO:0042454 406 0.019
negative regulation of cardioblast cell fate specification GO:0009997 1 0.019
regulation of dephosphorylation GO:0035303 96 0.019
hemopoiesis GO:0030097 180 0.019
positive regulation of organ growth GO:0046622 2 0.019
Fly
purine containing compound catabolic process GO:0072523 411 0.019
regulation of stem cell differentiation GO:2000736 56 0.019
regulation of binding GO:0051098 111 0.019
negative regulation of cardioblast differentiation GO:0051892 2 0.019
somatic muscle development GO:0007525 1 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
positive regulation of cell migration GO:0030335 172 0.019
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.019
immune response GO:0006955 307 0.019
regulation of hormone levels GO:0010817 125 0.019
glial cell migration GO:0008347 4 0.019
male genitalia development GO:0030539 1 0.019
neural tube closure GO:0001843 3 0.019
protein targeting to nucleus GO:0044744 104 0.019
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.019
stem cell differentiation GO:0048863 93 0.019
epithelial cell migration GO:0010631 119 0.018
ion transmembrane transport GO:0034220 338 0.018
endothelial cell migration GO:0043542 86 0.018
sequestering of calcium ion GO:0051208 17 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
taxis GO:0042330 157 0.018
Worm
positive regulation of programmed cell death GO:0043068 249 0.018
negative regulation of axon extension GO:0030517 2 0.018
extrinsic apoptotic signaling pathway GO:0097191 119 0.018
response to metal ion GO:0010038 84 0.018
Worm
hair follicle morphogenesis GO:0031069 2 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
nitrogen compound transport GO:0071705 191 0.018
endocytosis GO:0006897 159 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
keratinization GO:0031424 2 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
regulation of translation GO:0006417 89 0.017
Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
axon cargo transport GO:0008088 2 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
spindle organization GO:0007051 53 0.017
sequestering of metal ion GO:0051238 24 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
positive regulation of cytokine production GO:0001819 167 0.017
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.017
blood vessel morphogenesis GO:0048514 162 0.017
limbic system development GO:0021761 3 0.017
circadian behavior GO:0048512 2 0.017
dna replication GO:0006260 116 0.017
leukocyte differentiation GO:0002521 98 0.017
regulation of cell differentiation GO:0045595 393 0.017
Fly
regulation of protein catabolic process GO:0042176 155 0.017
macromolecule methylation GO:0043414 97 0.016
collateral sprouting GO:0048668 2 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
positive regulation of leukocyte activation GO:0002696 80 0.016
rna processing GO:0006396 255 0.016
cell projection morphogenesis GO:0048858 129 0.016
Fly
response to fungus GO:0009620 4 0.016
cerebral cortex cell migration GO:0021795 3 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
response to abiotic stimulus GO:0009628 336 0.016
cellular response to macrophage colony stimulating factor stimulus GO:0036006 4 0.016
negative regulation of cellular catabolic process GO:0031330 83 0.016
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
Fly
inflammatory response GO:0006954 79 0.016
epithelial cell proliferation GO:0050673 128 0.016
positive regulation of myeloid leukocyte mediated immunity GO:0002888 1 0.016
regulation of dendritic cell apoptotic process GO:2000668 4 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
angiogenesis GO:0001525 147 0.016
response to light stimulus GO:0009416 87 0.016
embryo development GO:0009790 123 0.016
Mouse Worm Fly
reactive oxygen species metabolic process GO:0072593 75 0.016
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.016
regulation of synaptic vesicle exocytosis GO:2000300 2 0.016
autophagy GO:0006914 88 0.016
Fly
protein autophosphorylation GO:0046777 123 0.016
lymphocyte activation GO:0046649 133 0.016
mast cell activation involved in immune response GO:0002279 4 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
Fly
regulation of mast cell degranulation GO:0043304 3 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.015
response to testosterone GO:0033574 1 0.015
regulation of protein targeting GO:1903533 91 0.015
regulation of anatomical structure size GO:0090066 101 0.015
Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
regulation of protein processing GO:0070613 150 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
regulation of chemotaxis GO:0050920 74 0.015
Worm
negative regulation of hydrolase activity GO:0051346 182 0.015
negative regulation of binding GO:0051100 57 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.015
nuclear import GO:0051170 106 0.015
wnt signaling pathway planar cell polarity pathway GO:0060071 5 0.015
positive regulation of exocytosis GO:0045921 35 0.015
protein kinase b signaling GO:0043491 69 0.015
regulation of microtubule based process GO:0032886 74 0.015
positive regulation of behavior GO:0048520 60 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
Fly
nuclear migration GO:0007097 1 0.015
negative regulation of response to external stimulus GO:0032102 83 0.015
serotonin transport GO:0006837 3 0.015
lipid phosphorylation GO:0046834 31 0.014
Human Mouse Rat Fly
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
actin mediated cell contraction GO:0070252 12 0.014
cell migration involved in gastrulation GO:0042074 1 0.014
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.014
hormone transport GO:0009914 68 0.014
rap protein signal transduction GO:0032486 7 0.014
cardioblast cell fate specification GO:0042685 1 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.014
negative regulation of blood circulation GO:1903523 4 0.014
interspecies interaction between organisms GO:0044419 156 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014

PIK3CB disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.064
Human
disease of cellular proliferation DOID:14566 174 0.064
Human
organ system cancer DOID:0050686 164 0.045
Human
disease of metabolism DOID:0014667 295 0.039
immune system disease DOID:2914 155 0.038
musculoskeletal system disease DOID:17 223 0.036
gastrointestinal system cancer DOID:3119 52 0.020
Human
hematopoietic system disease DOID:74 100 0.020
inherited metabolic disorder DOID:655 242 0.019
skin disease DOID:37 33 0.019
Human
integumentary system disease DOID:16 43 0.019
Human
central nervous system disease DOID:331 186 0.019
nervous system disease DOID:863 431 0.019
sensory system disease DOID:0050155 203 0.015
eye and adnexa disease DOID:1492 150 0.015