Homo sapiens

423 known processes

PKD2

polycystic kidney disease 2 (autosomal dominant)

(Aliases: MGC138468,APKD2,PC2,Pc-2,TRPP2,MGC138466,PKD4)

PKD2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
calcium ion transmembrane transport GO:0070588 76 0.998
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.989
positive regulation of cardiac muscle adaptation GO:0010615 1 0.981
cartilage condensation GO:0001502 1 0.978
metanephric nephron tubule morphogenesis GO:0072282 1 0.978
regulation of cardiac muscle hypertrophy in response to stress GO:1903242 2 0.967
cell aggregation GO:0098743 1 0.964
inorganic ion transmembrane transport GO:0098660 231 0.955
circulatory system development GO:0072359 262 0.948
cation transmembrane transport GO:0098655 238 0.947
cellular divalent inorganic cation homeostasis GO:0072503 128 0.932
ion homeostasis GO:0050801 230 0.929
metanephric tubule development GO:0072170 3 0.926
divalent inorganic cation transport GO:0072511 158 0.921
metanephric collecting duct development GO:0072205 2 0.917
cellular ion homeostasis GO:0006873 168 0.912
metal ion homeostasis GO:0055065 169 0.905
cellular cation homeostasis GO:0030003 163 0.897
cardiovascular system development GO:0072358 262 0.892
divalent metal ion transport GO:0070838 152 0.891
spinal cord development GO:0021510 4 0.885
detection of stimulus GO:0051606 85 0.883
Mouse
cation transport GO:0006812 331 0.878
metanephric distal tubule development GO:0072235 2 0.878
distal tubule development GO:0072017 4 0.859
cellular calcium ion homeostasis GO:0006874 117 0.852
metal ion transport GO:0030001 272 0.835
metanephric nephron tubule development GO:0072234 3 0.808
organ morphogenesis GO:0009887 147 0.805
metanephric nephron epithelium development GO:0072243 4 0.803
detection of mechanical stimulus GO:0050982 4 0.776
Mouse
maintenance of location GO:0051235 112 0.739
chemical homeostasis GO:0048878 306 0.733
regulation of cardiac muscle adaptation GO:0010612 2 0.728
transmembrane transport GO:0055085 399 0.703
metanephric nephron morphogenesis GO:0072273 7 0.696
kidney morphogenesis GO:0060993 19 0.648
cellular homeostasis GO:0019725 196 0.637
metanephric ascending thin limb development GO:0072218 2 0.625
morphogenesis of a branching structure GO:0001763 21 0.618
digestive tract development GO:0048565 75 0.616
maintenance of protein location GO:0045185 57 0.603
regulation of cytoplasmic transport GO:1903649 149 0.549
tube morphogenesis GO:0035239 95 0.518
lung epithelium development GO:0060428 7 0.501
positive regulation of muscle adaptation GO:0014744 1 0.496
nephron epithelium morphogenesis GO:0072088 15 0.487
nephron tubule morphogenesis GO:0072078 13 0.480
sequestering of calcium ion GO:0051208 17 0.471
cytosolic calcium ion homeostasis GO:0051480 89 0.464
embryonic placenta development GO:0001892 1 0.455
Mouse
nephron morphogenesis GO:0072028 15 0.440
metanephric tubule morphogenesis GO:0072173 1 0.433
regulation of cell adhesion GO:0030155 166 0.420
positive regulation of transferase activity GO:0051347 227 0.416
establishment of protein localization to organelle GO:0072594 172 0.414
positive regulation of protein phosphorylation GO:0001934 313 0.412
kidney development GO:0001822 53 0.410
maintenance of protein location in cell GO:0032507 56 0.408
regulation of spindle organization GO:0090224 10 0.383
mesonephric epithelium development GO:0072163 14 0.374
metanephric nephron development GO:0072210 9 0.368
anatomical structure formation involved in morphogenesis GO:0048646 284 0.367
protein localization to organelle GO:0033365 280 0.366
heart development GO:0007507 95 0.365
cell adhesion GO:0007155 325 0.362
digestive system development GO:0055123 75 0.346
detection of external stimulus GO:0009581 15 0.344
Mouse
peptidyl serine modification GO:0018209 106 0.343
renal tubule development GO:0061326 19 0.342
sequestering of metal ion GO:0051238 24 0.341
positive regulation of protein kinase activity GO:0045860 190 0.340
positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 1 0.335
detection of abiotic stimulus GO:0009582 15 0.326
Mouse
nephron epithelium development GO:0072009 23 0.325
connective tissue development GO:0061448 39 0.323
regulation of microtubule based process GO:0032886 74 0.321
intracellular protein transport GO:0006886 270 0.319
tube development GO:0035295 125 0.318
protein catabolic process GO:0030163 325 0.317
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.314
response to abiotic stimulus GO:0009628 336 0.311
regulation of cytoskeleton organization GO:0051493 177 0.310
collecting duct development GO:0072044 2 0.302
response to oxygen containing compound GO:1901700 369 0.301
peptidyl serine phosphorylation GO:0018105 101 0.293
biological adhesion GO:0022610 331 0.293
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.290
cytoplasmic sequestering of protein GO:0051220 12 0.289
cation homeostasis GO:0055080 189 0.288
regulation of calcium ion transport GO:0051924 79 0.288
regulation of ion transport GO:0043269 189 0.286
regulation of cell motility GO:2000145 299 0.281
tissue morphogenesis GO:0048729 96 0.280
branching morphogenesis of an epithelial tube GO:0048754 19 0.278
regulation of protein import into nucleus GO:0042306 78 0.273
central nervous system development GO:0007417 123 0.271
regulation of transferase activity GO:0051338 355 0.268
regulation of intracellular transport GO:0032386 195 0.261
associative learning GO:0008306 1 0.260
single organism nuclear import GO:1902593 104 0.259
jak stat cascade GO:0007259 46 0.258
Mouse
regulation of ion homeostasis GO:2000021 73 0.254
negative regulation of transport GO:0051051 176 0.252
calcium ion transport GO:0006816 147 0.248
release of sequestered calcium ion into cytosol GO:0051209 41 0.248
cytosolic calcium ion transport GO:0060401 48 0.246
negative regulation of protein transport GO:0051224 75 0.239
skeletal system development GO:0001501 79 0.234
epithelial tube morphogenesis GO:0060562 38 0.233
mesonephric tubule development GO:0072164 14 0.232
regulation of microtubule cytoskeleton organization GO:0070507 61 0.227
mesonephros development GO:0001823 17 0.223
gland development GO:0048732 48 0.223
cytoplasmic transport GO:0016482 379 0.221
regulation of protein localization to nucleus GO:1900180 85 0.219
regulation of cell migration GO:0030334 289 0.217
cell cycle arrest GO:0007050 71 0.214
nuclear transport GO:0051169 179 0.212
negative regulation of homeostatic process GO:0032845 59 0.209
morphogenesis of an epithelium GO:0002009 60 0.203
positive regulation of developmental process GO:0051094 314 0.203
regulation of kinase activity GO:0043549 314 0.201
regulation of intracellular protein transport GO:0033157 123 0.200
distal tubule morphogenesis GO:0072156 3 0.199
single organism cellular localization GO:1902580 332 0.194
neural tube development GO:0021915 9 0.192
cellular macromolecule catabolic process GO:0044265 380 0.191
positive regulation of cell cycle GO:0045787 140 0.189
positive regulation of phosphorylation GO:0042327 394 0.186
microtubule based process GO:0007017 210 0.186
urogenital system development GO:0001655 65 0.174
rhodopsin mediated signaling pathway GO:0016056 1 0.173
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle GO:0031657 9 0.171
single organism cell adhesion GO:0098602 179 0.169
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.165
microtubule cytoskeleton organization GO:0000226 176 0.164
inorganic cation transmembrane transport GO:0098662 194 0.163
nephron tubule development GO:0072080 17 0.160
protein import GO:0017038 130 0.159
cell cycle phase transition GO:0044770 173 0.159
cell projection organization GO:0030030 252 0.158
mitotic cell cycle GO:0000278 326 0.156
divalent inorganic cation homeostasis GO:0072507 136 0.156
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.155
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.155
cellular protein catabolic process GO:0044257 261 0.153
neuron differentiation GO:0030182 138 0.153
nervous system development GO:0007399 293 0.152
protein localization to nucleus GO:0034504 136 0.150
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.150
protein targeting to nucleus GO:0044744 104 0.149
blood vessel morphogenesis GO:0048514 162 0.148
nucleoside catabolic process GO:0009164 408 0.147
respiratory tube development GO:0030323 20 0.144
cell development GO:0048468 328 0.143
regulation of homeostatic process GO:0032844 121 0.140
skin development GO:0043588 76 0.140
positive regulation of binding GO:0051099 45 0.139
regulation of protein targeting GO:1903533 91 0.137
vasculature development GO:0001944 181 0.136
single organismal cell cell adhesion GO:0016337 148 0.135
chordate embryonic development GO:0043009 34 0.132
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle GO:0031659 8 0.131
regulation of cellular amino acid metabolic process GO:0006521 6 0.129
ion transmembrane transport GO:0034220 338 0.124
proteasomal protein catabolic process GO:0010498 176 0.124
phototransduction visible light GO:0007603 2 0.124
regulation of proteasomal protein catabolic process GO:0061136 87 0.123
sensory perception of light stimulus GO:0050953 35 0.120
segmentation GO:0035282 4 0.120
regulation of protein catabolic process GO:0042176 155 0.119
regulation of transcription factor import into nucleus GO:0042990 39 0.119
regulation of sequestering of calcium ion GO:0051282 41 0.117
regulation of cell cycle GO:0051726 393 0.116
morphogenesis of a branching epithelium GO:0061138 20 0.115
response to calcium ion GO:0051592 46 0.113
blood vessel development GO:0001568 172 0.111
negative regulation of protein localization to nucleus GO:1900181 34 0.110
g1 s transition of mitotic cell cycle GO:0000082 78 0.110
post embryonic development GO:0009791 2 0.110
regulation of cellular protein catabolic process GO:1903362 96 0.109
nucleocytoplasmic transport GO:0006913 176 0.107
muscle system process GO:0003012 81 0.106
Zebrafish
cartilage development GO:0051216 31 0.105
positive regulation of protein binding GO:0032092 24 0.104
nucleoside triphosphate catabolic process GO:0009143 394 0.103
secretion GO:0046903 254 0.101
phototransduction GO:0007602 3 0.100
negative regulation of protein import into nucleus GO:0042308 30 0.100
lymph vessel morphogenesis GO:0036303 7 0.098
Zebrafish
regulation of cell differentiation GO:0045595 393 0.098
regulation of protein binding GO:0043393 66 0.097
single organism membrane organization GO:0044802 268 0.096
cardiac muscle hypertrophy in response to stress GO:0014898 4 0.096
visual perception GO:0007601 27 0.094
calcium ion import GO:0070509 23 0.094
respiratory system development GO:0060541 22 0.093
nucleotide catabolic process GO:0009166 408 0.091
cellular amine metabolic process GO:0044106 41 0.091
regulation of system process GO:0044057 101 0.090
Zebrafish
lymph vessel development GO:0001945 9 0.089
Zebrafish
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.088
sensory perception GO:0007600 103 0.088
regulation of proteolysis GO:0030162 293 0.087
lung development GO:0030324 20 0.087
regulation of calcium ion transport into cytosol GO:0010522 33 0.085
cell morphogenesis involved in differentiation GO:0000904 144 0.085
cell projection assembly GO:0030031 126 0.085
nucleoside triphosphate metabolic process GO:0009141 422 0.083
cellular response to histamine GO:0071420 3 0.082
system process GO:0003008 349 0.082
Zebrafish
cell cycle g1 s phase transition GO:0044843 80 0.082
cellular response to abiotic stimulus GO:0071214 117 0.081
epithelium development GO:0060429 227 0.080
immune response GO:0006955 307 0.080
ossification GO:0001503 121 0.077
regulation of protein transport GO:0051223 213 0.076
actin cytoskeleton organization GO:0030036 207 0.075
regulation of cellular amine metabolic process GO:0033238 11 0.075
response to organonitrogen compound GO:0010243 156 0.074
striated muscle adaptation GO:0014888 4 0.073
regulation of cell cycle process GO:0010564 266 0.073
organophosphate catabolic process GO:0046434 430 0.073
nuclear export GO:0051168 69 0.072
epithelial cell proliferation GO:0050673 128 0.072
purine nucleoside triphosphate catabolic process GO:0009146 392 0.071
embryo development GO:0009790 123 0.071
ribonucleoside catabolic process GO:0042454 406 0.070
calcium mediated signaling GO:0019722 44 0.070
Zebrafish
response to organic cyclic compound GO:0014070 204 0.070
regulation of cell morphogenesis GO:0022604 153 0.069
brain development GO:0007420 97 0.069
establishment or maintenance of cell polarity GO:0007163 31 0.068
cell junction organization GO:0034330 79 0.068
locomotory behavior GO:0007626 1 0.066
cellular metal ion homeostasis GO:0006875 146 0.065
hepaticobiliary system development GO:0061008 10 0.065
negative regulation of intracellular transport GO:0032387 60 0.065
vesicle mediated transport GO:0016192 371 0.064
second messenger mediated signaling GO:0019932 78 0.064
negative regulation of intracellular protein transport GO:0090317 42 0.064
detection of light stimulus involved in visual perception GO:0050908 9 0.063
multicellular organismal aging GO:0010259 3 0.063
cellular ketone metabolic process GO:0042180 80 0.063
regulation of epithelial cell migration GO:0010632 93 0.062
neurological system process GO:0050877 163 0.061
regulation of endothelial cell migration GO:0010594 67 0.061
regulation of binding GO:0051098 111 0.060
nucleoside phosphate catabolic process GO:1901292 412 0.060
cellular component morphogenesis GO:0032989 314 0.058
regulation of transmembrane transporter activity GO:0022898 74 0.058
positive regulation of transporter activity GO:0032411 32 0.058
positive regulation of transport GO:0051050 336 0.058
purine nucleoside monophosphate catabolic process GO:0009128 158 0.057
embryonic organ development GO:0048568 36 0.057
amine metabolic process GO:0009308 44 0.056
rhythmic behavior GO:0007622 2 0.056
regulation of mitotic spindle organization GO:0060236 6 0.055
regulation of neuron differentiation GO:0045664 70 0.054
response to mechanical stimulus GO:0009612 51 0.054
Mouse
oogenesis GO:0048477 2 0.053
positive regulation of cell differentiation GO:0045597 211 0.053
generation of neurons GO:0048699 152 0.052
single organism reproductive process GO:0044702 98 0.052
Mouse
innate immune response GO:0045087 178 0.052
atp catabolic process GO:0006200 157 0.052
purine ribonucleoside metabolic process GO:0046128 437 0.052
regulation of nervous system development GO:0051960 88 0.051
regulation of mitotic cell cycle GO:0007346 189 0.051
protein export from nucleus GO:0006611 29 0.051
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.050
growth GO:0040007 202 0.050
positive regulation of immune system process GO:0002684 283 0.050
positive regulation of homeostatic process GO:0032846 47 0.049
signal transduction by phosphorylation GO:0023014 297 0.049
anion transport GO:0006820 161 0.049
negative regulation of multicellular organismal process GO:0051241 317 0.049
hemopoiesis GO:0030097 180 0.049
negative regulation of bmp signaling pathway GO:0030514 17 0.049
defense response GO:0006952 315 0.047
heart morphogenesis GO:0003007 48 0.047
regulation of muscle system process GO:0090257 53 0.047
Zebrafish
nucleoside monophosphate catabolic process GO:0009125 159 0.046
saliva secretion GO:0046541 2 0.045
ribonucleoside monophosphate metabolic process GO:0009161 187 0.045
negative regulation of cell proliferation GO:0008285 228 0.044
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.044
regulation of protein kinase activity GO:0045859 289 0.044
regulation of growth GO:0040008 165 0.043
skeletal system morphogenesis GO:0048705 24 0.042
ameboidal type cell migration GO:0001667 135 0.042
positive regulation of catabolic process GO:0009896 310 0.042
regulation of ion transmembrane transport GO:0034765 132 0.042
purine ribonucleoside catabolic process GO:0046130 398 0.042
spindle organization GO:0007051 53 0.042
immune effector process GO:0002252 159 0.042
regulation of transmembrane transport GO:0034762 139 0.042
cellular amino acid metabolic process GO:0006520 116 0.041
osteoblast differentiation GO:0001649 92 0.041
positive regulation of hydrolase activity GO:0051345 331 0.041
regulation of cell projection organization GO:0031344 107 0.041
response to metal ion GO:0010038 84 0.041
bmp signaling pathway GO:0030509 49 0.041
developmental process involved in reproduction GO:0003006 66 0.040
Mouse
positive regulation of ion transmembrane transport GO:0034767 40 0.040
negative regulation of locomotion GO:0040013 118 0.039
regulation of body fluid levels GO:0050878 99 0.039
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.039
sensory perception of sound GO:0007605 37 0.039
purine nucleoside triphosphate metabolic process GO:0009144 412 0.039
salivary gland morphogenesis GO:0007435 4 0.038
positive regulation of transmembrane transport GO:0034764 41 0.038
purine containing compound catabolic process GO:0072523 411 0.038
epithelial cell differentiation GO:0030855 141 0.038
cytokine production GO:0001816 247 0.038
regulation of ossification GO:0030278 58 0.038
endomembrane system organization GO:0010256 196 0.038
mating GO:0007618 1 0.038
Worm
spermatid differentiation GO:0048515 4 0.038
cell morphogenesis GO:0000902 296 0.037
embryonic morphogenesis GO:0048598 85 0.037
calcium ion homeostasis GO:0055074 122 0.037
hematopoietic or lymphoid organ development GO:0048534 186 0.037
regulation of cellular response to growth factor stimulus GO:0090287 76 0.036
behavior GO:0007610 112 0.036
Worm
blastoderm segmentation GO:0007350 2 0.036
purine nucleotide catabolic process GO:0006195 405 0.036
mitotic cell cycle process GO:1903047 286 0.036
response to radiation GO:0009314 151 0.035
circadian behavior GO:0048512 2 0.035
negative regulation of developmental process GO:0051093 247 0.035
purine ribonucleotide catabolic process GO:0009154 404 0.035
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.034
positive regulation of cell migration GO:0030335 172 0.034
vasculogenesis GO:0001570 8 0.034
regulation of mapk cascade GO:0043408 262 0.034
negative regulation of cellular component movement GO:0051271 106 0.034
detection of visible light GO:0009584 11 0.034
wnt signaling pathway GO:0016055 156 0.034
endothelial cell migration GO:0043542 86 0.033
positive regulation of cytoplasmic transport GO:1903651 82 0.033
regulation of cellular ketone metabolic process GO:0010565 50 0.033
cellular chemical homeostasis GO:0055082 180 0.033
regulation of actin cytoskeleton organization GO:0032956 116 0.032
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.032
positive regulation of nucleotide metabolic process GO:0045981 230 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
regulation of cell development GO:0060284 161 0.031
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.031
positive regulation of cellular catabolic process GO:0031331 284 0.031
atp metabolic process GO:0046034 176 0.031
negative regulation of cellular amine metabolic process GO:0033239 3 0.031
compound eye development GO:0048749 1 0.031
regulation of nucleoside metabolic process GO:0009118 209 0.031
ribonucleoside monophosphate catabolic process GO:0009158 158 0.031
tripartite regional subdivision GO:0007351 2 0.031
endothelial cell proliferation GO:0001935 65 0.031
response to light stimulus GO:0009416 87 0.031
regulation of canonical wnt signaling pathway GO:0060828 88 0.031
regulation of multi organism process GO:0043900 157 0.031
regulation of purine nucleotide catabolic process GO:0033121 205 0.030
regulation of establishment of protein localization GO:0070201 242 0.030
regulation of actin filament based process GO:0032970 141 0.030
establishment of cell polarity GO:0030010 22 0.030
immune system development GO:0002520 195 0.030
placenta development GO:0001890 10 0.030
Mouse
membrane organization GO:0061024 292 0.030
regulation of bmp signaling pathway GO:0030510 27 0.029
actin mediated cell contraction GO:0070252 12 0.029
cell substrate adhesion GO:0031589 132 0.029
positive regulation of cell proliferation GO:0008284 301 0.029
memory GO:0007613 3 0.028
positive regulation of cell death GO:0010942 263 0.028
positive regulation of gtpase activity GO:0043547 166 0.028
cellular component disassembly GO:0022411 92 0.028
actin filament based process GO:0030029 224 0.028
g protein coupled receptor signaling pathway GO:0007186 207 0.028
regeneration GO:0031099 4 0.028
regulation of epithelial cell proliferation GO:0050678 113 0.028
regulation of cell substrate adhesion GO:0010810 68 0.028
determination of adult lifespan GO:0008340 2 0.028
detection of stimulus involved in sensory perception GO:0050906 43 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
anterior posterior axis specification GO:0009948 2 0.027
purine nucleoside monophosphate metabolic process GO:0009126 186 0.027
cell division GO:0051301 168 0.027
response to oxygen levels GO:0070482 100 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
regulation of wnt signaling pathway GO:0030111 123 0.026
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
positive regulation of cellular component movement GO:0051272 181 0.026
tissue migration GO:0090130 119 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.026
regulation of ion transmembrane transporter activity GO:0032412 72 0.026
response to organophosphorus GO:0046683 41 0.026
sensory organ development GO:0007423 52 0.026
regulation of cellular component movement GO:0051270 334 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.026
Mouse
digestive system process GO:0022600 17 0.025
muscle hypertrophy GO:0014896 14 0.025
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.025
positive regulation of muscle hypertrophy GO:0014742 6 0.025
purine nucleoside catabolic process GO:0006152 398 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
spinal cord dorsal ventral patterning GO:0021513 2 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.025
actin filament organization GO:0007015 128 0.025
negative regulation of cell migration GO:0030336 102 0.025
response to other organism GO:0051707 261 0.025
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 16 0.025
anterior posterior axis specification embryo GO:0008595 2 0.025
response to external biotic stimulus GO:0043207 261 0.025
female gamete generation GO:0007292 2 0.024
digestion GO:0007586 22 0.024
positive regulation of synaptic transmission GO:0050806 4 0.024
response to cytokine GO:0034097 232 0.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.024
neuron projection regeneration GO:0031102 1 0.024
regulation of cellular component size GO:0032535 82 0.024
melanin metabolic process GO:0006582 1 0.024
regulation of osteoblast differentiation GO:0045667 38 0.024
cellular response to ammonium ion GO:0071242 4 0.023
epithelial cell migration GO:0010631 119 0.023
enzyme linked receptor protein signaling pathway GO:0007167 303 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
negative regulation of sequestering of calcium ion GO:0051283 41 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
response to biotic stimulus GO:0009607 276 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.023
protein localization to membrane GO:0072657 160 0.022
response to transforming growth factor beta GO:0071559 94 0.022
organelle assembly GO:0070925 176 0.022
negative regulation of smoothened signaling pathway GO:0045879 3 0.022
regulation of immune response GO:0050776 201 0.022
regulation of metal ion transport GO:0010959 120 0.022
morphogenesis of a polarized epithelium GO:0001738 3 0.022
midgut development GO:0007494 1 0.022
stem cell division GO:0017145 2 0.022
response to growth factor GO:0070848 205 0.022
negative regulation of cell motility GO:2000146 104 0.022
sex differentiation GO:0007548 45 0.022
protein ubiquitination GO:0016567 314 0.022
regulation of locomotion GO:0040012 329 0.021
cardiac muscle hypertrophy GO:0003300 14 0.021
reproductive process GO:0022414 106 0.021
Mouse Worm
liver development GO:0001889 9 0.021
inner ear morphogenesis GO:0042472 4 0.021
cell part morphogenesis GO:0032990 137 0.021
regulation of endothelial cell proliferation GO:0001936 56 0.021
regulation of protein localization GO:0032880 296 0.021
organic hydroxy compound metabolic process GO:1901615 147 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
regulation of neuron projection development GO:0010975 57 0.021
cellular response to oxygen containing compound GO:1901701 276 0.020
regulation of muscle hypertrophy GO:0014743 10 0.020
cellular amide metabolic process GO:0043603 69 0.020
cell projection morphogenesis GO:0048858 129 0.020
positive regulation of cell motility GO:2000147 177 0.020
actin filament based movement GO:0030048 17 0.020
interspecies interaction between organisms GO:0044419 156 0.020
response to wounding GO:0009611 168 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
adult locomotory behavior GO:0008344 1 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
epithelial cell morphogenesis GO:0003382 8 0.020
regulation of behavior GO:0050795 82 0.020
spermatid development GO:0007286 4 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
neuron projection development GO:0031175 106 0.020
meiosis i GO:0007127 4 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.019
extrinsic apoptotic signaling pathway GO:0097191 119 0.019
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.019
somitogenesis GO:0001756 2 0.019
embryonic epithelial tube formation GO:0001838 4 0.019
cellular response to hypoxia GO:0071456 51 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
Mouse
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
positive regulation of cell adhesion GO:0045785 84 0.019
regulation of growth rate GO:0040009 1 0.019
endocytosis GO:0006897 159 0.019
neuromuscular junction development GO:0007528 3 0.019
maintenance of location in cell GO:0051651 62 0.019

PKD2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.089
sensory system disease DOID:0050155 203 0.070
nervous system disease DOID:863 431 0.070
auditory system disease DOID:2742 53 0.039
nonsyndromic deafness DOID:0050563 50 0.036
connective tissue disease DOID:65 109 0.028
disease of cellular proliferation DOID:14566 174 0.020