Homo sapiens

16 known processes

PKN3

protein kinase N3

(Aliases: RP11-545E17.1)

PKN3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 73 0.881
rho protein signal transduction GO:0007266 26 0.874
guanosine containing compound metabolic process GO:1901068 244 0.851
nucleoside catabolic process GO:0009164 408 0.850
purine ribonucleotide catabolic process GO:0009154 404 0.773
ribonucleotide catabolic process GO:0009261 405 0.765
organophosphate catabolic process GO:0046434 430 0.732
purine containing compound catabolic process GO:0072523 411 0.711
nucleoside triphosphate metabolic process GO:0009141 422 0.708
purine ribonucleoside metabolic process GO:0046128 437 0.704
regulation of rho protein signal transduction GO:0035023 79 0.657
regulation of gtp catabolic process GO:0033124 180 0.612
purine nucleotide catabolic process GO:0006195 405 0.610
purine ribonucleoside catabolic process GO:0046130 398 0.603
gtp catabolic process GO:0006184 237 0.596
positive regulation of gtp catabolic process GO:0033126 166 0.574
purine nucleoside triphosphate catabolic process GO:0009146 392 0.569
regulation of small gtpase mediated signal transduction GO:0051056 156 0.561
small gtpase mediated signal transduction GO:0007264 78 0.552
glycosyl compound catabolic process GO:1901658 413 0.551
guanosine containing compound catabolic process GO:1901069 239 0.540
nucleoside triphosphate catabolic process GO:0009143 394 0.534
regulation of nucleotide catabolic process GO:0030811 205 0.531
positive regulation of rho gtpase activity GO:0032321 56 0.531
positive regulation of nucleotide metabolic process GO:0045981 230 0.493
regulation of gtpase activity GO:0043087 180 0.492
nucleoside phosphate catabolic process GO:1901292 412 0.486
positive regulation of cellular catabolic process GO:0031331 284 0.482
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.475
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.467
nucleotide catabolic process GO:0009166 408 0.460
positive regulation of ras gtpase activity GO:0032320 117 0.456
regulation of purine nucleotide metabolic process GO:1900542 264 0.441
regulation of nucleoside metabolic process GO:0009118 209 0.425
ribonucleoside triphosphate catabolic process GO:0009203 391 0.416
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.416
purine nucleoside triphosphate metabolic process GO:0009144 412 0.403
regulation of rho gtpase activity GO:0032319 66 0.393
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.384
regulation of ras protein signal transduction GO:0046578 155 0.366
regulation of purine nucleotide catabolic process GO:0033121 205 0.361
regulation of ras gtpase activity GO:0032318 128 0.348
negative regulation of apoptotic process GO:0043066 316 0.335
regulation of nucleotide metabolic process GO:0006140 269 0.302
negative regulation of programmed cell death GO:0043069 321 0.290
positive regulation of catabolic process GO:0009896 310 0.258
negative regulation of cell death GO:0060548 345 0.251
positive regulation of nucleoside metabolic process GO:0045979 186 0.240
positive regulation of hydrolase activity GO:0051345 331 0.211
golgi vesicle fusion to target membrane GO:0048210 2 0.129
cellular lipid metabolic process GO:0044255 303 0.116
endomembrane system organization GO:0010256 196 0.088
phosphatidic acid biosynthetic process GO:0006654 4 0.086
regulation of cell motility GO:2000145 299 0.085
Human
phototransduction GO:0007602 3 0.084
organophosphate biosynthetic process GO:0090407 163 0.082
regulation of locomotion GO:0040012 329 0.081
Human
defense response GO:0006952 315 0.080
lipid catabolic process GO:0016042 84 0.064
phospholipid catabolic process GO:0009395 12 0.054
defense response to bacterium GO:0042742 63 0.054
post embryonic development GO:0009791 2 0.053
Fly
phosphatidic acid metabolic process GO:0046473 5 0.052
response to external biotic stimulus GO:0043207 261 0.047
positive regulation of cellular component movement GO:0051272 181 0.046
response to light stimulus GO:0009416 87 0.041
amine metabolic process GO:0009308 44 0.041
glycerolipid metabolic process GO:0046486 107 0.040
positive regulation of cellular amine metabolic process GO:0033240 7 0.040
regulation of cellular ketone metabolic process GO:0010565 50 0.037
lipid metabolic process GO:0006629 381 0.037
positive regulation of cellular component organization GO:0051130 376 0.036
response to nitrogen compound GO:1901698 184 0.034
cellular amino acid metabolic process GO:0006520 116 0.034
membrane organization GO:0061024 292 0.034
response to hormone GO:0009725 175 0.034
regulation of cell migration GO:0030334 289 0.033
female gamete generation GO:0007292 2 0.033
response to abiotic stimulus GO:0009628 336 0.033
regulation of cellular amine metabolic process GO:0033238 11 0.032
multicellular organismal aging GO:0010259 3 0.032
determination of adult lifespan GO:0008340 2 0.032
ribonucleoside catabolic process GO:0042454 406 0.031
response to radiation GO:0009314 151 0.031
purine nucleoside catabolic process GO:0006152 398 0.031
detection of stimulus GO:0051606 85 0.031
regulation of cellular amino acid metabolic process GO:0006521 6 0.030
lipid biosynthetic process GO:0008610 177 0.030
immune response GO:0006955 307 0.030
positive regulation of transport GO:0051050 336 0.030
regulation of intracellular transport GO:0032386 195 0.029
ribonucleoside triphosphate metabolic process GO:0009199 412 0.029
positive regulation of locomotion GO:0040017 186 0.029
regulation of cellular component movement GO:0051270 334 0.029
Human
golgi vesicle transport GO:0048193 80 0.029
cell morphogenesis GO:0000902 296 0.029
anatomical structure formation involved in morphogenesis GO:0048646 284 0.027
response to bacterium GO:0009617 144 0.027
cellular ketone metabolic process GO:0042180 80 0.027
response to oxygen containing compound GO:1901700 369 0.026
regulation of cell cycle GO:0051726 393 0.026
Human
regulation of proteolysis GO:0030162 293 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
response to other organism GO:0051707 261 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
cellular component morphogenesis GO:0032989 314 0.025
cellular amine metabolic process GO:0044106 41 0.024
positive regulation of phosphorylation GO:0042327 394 0.024
organelle fusion GO:0048284 36 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
oogenesis GO:0048477 2 0.023
detection of abiotic stimulus GO:0009582 15 0.023
regulation of cell differentiation GO:0045595 393 0.023
positive regulation of organelle organization GO:0010638 195 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
protein maturation GO:0051604 233 0.023
single organism membrane fusion GO:0044801 37 0.022
glycerolipid biosynthetic process GO:0045017 51 0.022
glycerophospholipid metabolic process GO:0006650 84 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
regulation of cellular component biogenesis GO:0044087 281 0.022
positive regulation of cell motility GO:2000147 177 0.022
positive regulation of cell migration GO:0030335 172 0.022
regulation of cell cycle process GO:0010564 266 0.022
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
positive regulation of intracellular transport GO:0032388 104 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
segmentation GO:0035282 4 0.021
regulation of vesicle mediated transport GO:0060627 130 0.021
phospholipid metabolic process GO:0006644 99 0.021
protein catabolic process GO:0030163 325 0.020
regeneration GO:0031099 4 0.020
mitotic cell cycle GO:0000278 326 0.020
Human
transmembrane transport GO:0055085 399 0.020
actin filament based process GO:0030029 224 0.020
Fly
neuromuscular junction development GO:0007528 3 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
locomotory behavior GO:0007626 1 0.020
defense response to gram positive bacterium GO:0050830 29 0.019
defense response to other organism GO:0098542 129 0.019
apoptotic signaling pathway GO:0097190 268 0.019
cellular protein catabolic process GO:0044257 261 0.019
blastoderm segmentation GO:0007350 2 0.018
regulation of kinase activity GO:0043549 314 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.018
cellular lipid catabolic process GO:0044242 65 0.018
protein localization to organelle GO:0033365 280 0.018
cell adhesion GO:0007155 325 0.018
regulation of transferase activity GO:0051338 355 0.018
gtp metabolic process GO:0046039 239 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
chromatin organization GO:0006325 351 0.018
Human
regulation of mapk cascade GO:0043408 262 0.018
vesicle organization GO:0016050 62 0.018
regulation of protein kinase activity GO:0045859 289 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
chromatin modification GO:0016568 298 0.017
Human
cellular macromolecule catabolic process GO:0044265 380 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
cytokine production GO:0001816 247 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.016
Fly
anterior posterior axis specification GO:0009948 2 0.016
oocyte development GO:0048599 1 0.016
vesicle fusion GO:0006906 17 0.016
protein processing GO:0016485 226 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
positive regulation of immune system process GO:0002684 283 0.016
negative regulation of cell cycle GO:0045786 193 0.016
oocyte differentiation GO:0009994 2 0.016
peripheral nervous system development GO:0007422 2 0.016
innate immune response GO:0045087 178 0.016
single organism membrane organization GO:0044802 268 0.016
memory GO:0007613 3 0.016
protein targeting GO:0006605 187 0.016
protein ubiquitination GO:0016567 314 0.016
neurotransmitter secretion GO:0007269 4 0.016
regulation of cellular response to stress GO:0080135 244 0.016
spermatid differentiation GO:0048515 4 0.015
monocarboxylic acid metabolic process GO:0032787 185 0.015
organ formation GO:0048645 3 0.015
small molecule biosynthetic process GO:0044283 157 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
hindbrain development GO:0030902 3 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
regulation of protein transport GO:0051223 213 0.015
cell fate determination GO:0001709 3 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
positive regulation of kinase activity GO:0033674 204 0.015
glial cell migration GO:0008347 4 0.015
positive regulation of protein kinase activity GO:0045860 190 0.015
actin cytoskeleton organization GO:0030036 207 0.015
Fly
single organism cellular localization GO:1902580 332 0.015
cell projection organization GO:0030030 252 0.015
cell cycle phase transition GO:0044770 173 0.014
cytoplasmic transport GO:0016482 379 0.014
regulation of cytokine production GO:0001817 232 0.014
response to biotic stimulus GO:0009607 276 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
spermatid development GO:0007286 4 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
rhythmic behavior GO:0007622 2 0.014
negative regulation of transport GO:0051051 176 0.014
membrane fusion GO:0061025 43 0.014
mitotic cell cycle process GO:1903047 286 0.014
neural tube formation GO:0001841 3 0.014
vesicle mediated transport GO:0016192 371 0.014
negative regulation of protein modification process GO:0031400 200 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
adult locomotory behavior GO:0008344 1 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
inner ear morphogenesis GO:0042472 4 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
intracellular protein transport GO:0006886 270 0.013
tripartite regional subdivision GO:0007351 2 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
neuroblast proliferation GO:0007405 4 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
cell activation GO:0001775 213 0.013
nuclear transport GO:0051169 179 0.013
dephosphorylation GO:0016311 209 0.013
motor neuron axon guidance GO:0008045 2 0.013
nervous system development GO:0007399 293 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
cell division GO:0051301 168 0.013
Human
single organismal cell cell adhesion GO:0016337 148 0.013
multi organism cellular process GO:0044764 156 0.013
protein oligomerization GO:0051259 173 0.013
rna processing GO:0006396 255 0.013
microtubule based process GO:0007017 210 0.013
compound eye development GO:0048749 1 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
establishment of planar polarity GO:0001736 3 0.013
cell projection assembly GO:0030031 126 0.013
system process GO:0003008 349 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
biological adhesion GO:0022610 331 0.013
nitrogen compound transport GO:0071705 191 0.013
ion transmembrane transport GO:0034220 338 0.013
embryonic epithelial tube formation GO:0001838 4 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
atp metabolic process GO:0046034 176 0.013
primary neural tube formation GO:0014020 3 0.013
negative regulation of cell proliferation GO:0008285 228 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
salivary gland morphogenesis GO:0007435 4 0.012
anion transport GO:0006820 161 0.012
blood vessel development GO:0001568 172 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
growth GO:0040007 202 0.012
cardiovascular system development GO:0072358 262 0.012
cellular homeostasis GO:0019725 196 0.012
neurogenesis GO:0022008 169 0.012
ion homeostasis GO:0050801 230 0.012
regulation of response to external stimulus GO:0032101 222 0.012
protein localization to membrane GO:0072657 160 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
metencephalon development GO:0022037 2 0.012
negative regulation of protein processing GO:0010955 142 0.012
dna repair GO:0006281 198 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
maintenance of location GO:0051235 112 0.012
positive regulation of vesicle fusion GO:0031340 4 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
cation transmembrane transport GO:0098655 238 0.012
regulation of protein localization GO:0032880 296 0.012
morphogenesis of a polarized epithelium GO:0001738 3 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
ameboidal type cell migration GO:0001667 135 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
meiosis i GO:0007127 4 0.012
positive regulation of proteolysis GO:0045862 142 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
positive regulation of cytokine production GO:0001819 167 0.012
response to fungus GO:0009620 4 0.012
mitochondrion organization GO:0007005 156 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
metal ion transport GO:0030001 272 0.012
golgi organization GO:0007030 38 0.012
fatty acid metabolic process GO:0006631 115 0.011
cellular chemical homeostasis GO:0055082 180 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
mating GO:0007618 1 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
regulation of protein catabolic process GO:0042176 155 0.011
glycerophospholipid biosynthetic process GO:0046474 40 0.011
response to organonitrogen compound GO:0010243 156 0.011
actin mediated cell contraction GO:0070252 12 0.011
wnt signaling pathway GO:0016055 156 0.011
organic acid biosynthetic process GO:0016053 97 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
response to axon injury GO:0048678 1 0.011
organelle assembly GO:0070925 176 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
viral process GO:0016032 146 0.011
positive regulation of developmental process GO:0051094 314 0.011
specification of organ identity GO:0010092 3 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
cellular protein complex assembly GO:0043623 188 0.011
regulation of dna metabolic process GO:0051052 153 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
positive regulation of immune response GO:0050778 159 0.011
circadian behavior GO:0048512 2 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
covalent chromatin modification GO:0016569 254 0.011
Human
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.011
negative regulation of synaptic transmission GO:0050805 2 0.011
tube closure GO:0060606 3 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
Human
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
cell part morphogenesis GO:0032990 137 0.011
protein modification by small protein conjugation GO:0032446 342 0.011
cerebellum development GO:0021549 2 0.011
rna interference GO:0016246 4 0.011
negative regulation of locomotion GO:0040013 118 0.011
protein autophosphorylation GO:0046777 123 0.011
Fly
secretion by cell GO:0032940 226 0.011
interspecies interaction between organisms GO:0044419 156 0.011
neuron development GO:0048666 113 0.011
response to inorganic substance GO:0010035 127 0.011
cilium morphogenesis GO:0060271 75 0.011
tissue regeneration GO:0042246 3 0.011
histone modification GO:0016570 251 0.011
Human
epithelial cell proliferation GO:0050673 128 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
neural tube closure GO:0001843 3 0.010
central nervous system development GO:0007417 123 0.010
negative regulation of proteolysis GO:0045861 132 0.010
somatic stem cell maintenance GO:0035019 4 0.010
response to growth factor GO:0070848 205 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
neuron differentiation GO:0030182 138 0.010
cellular response to abiotic stimulus GO:0071214 117 0.010
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
atp catabolic process GO:0006200 157 0.010
positive regulation of protein transport GO:0051222 135 0.010
regulation of neurotransmitter secretion GO:0046928 3 0.010
cell growth GO:0016049 160 0.010
engulfment of apoptotic cell GO:0043652 2 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
sulfur compound metabolic process GO:0006790 101 0.010
neural crest cell development GO:0014032 3 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
divalent metal ion transport GO:0070838 152 0.010
calcium ion transport GO:0006816 147 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
positive regulation of cell cycle GO:0045787 140 0.010
Human
sequestering of metal ion GO:0051238 24 0.010
cation homeostasis GO:0055080 189 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
cilium organization GO:0044782 68 0.010
positive regulation of mapk cascade GO:0043410 190 0.010
limbic system development GO:0021761 3 0.010
cell cycle checkpoint GO:0000075 117 0.010

PKN3 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.231
disease of cellular proliferation DOID:14566 174 0.231
organ system cancer DOID:0050686 164 0.183
musculoskeletal system disease DOID:17 223 0.027
disease of metabolism DOID:0014667 295 0.025
immune system cancer DOID:0060083 36 0.020
connective tissue disease DOID:65 109 0.019
sensory system disease DOID:0050155 203 0.016
nervous system disease DOID:863 431 0.016
bone disease DOID:0080001 88 0.015
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
central nervous system disease DOID:331 186 0.013
neurodegenerative disease DOID:1289 102 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
retinal disease DOID:5679 118 0.011
inherited metabolic disorder DOID:655 242 0.011
immune system disease DOID:2914 155 0.011
bone development disease DOID:0080006 55 0.011
myopathy DOID:423 104 0.011