Homo sapiens

111 known processes

PKP2

plakophilin 2

(Aliases: MGC177501,ARVD9)

PKP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
keratinization GO:0031424 2 0.968
asymmetric stem cell division GO:0098722 1 0.951
cell fate determination GO:0001709 3 0.914
somatic stem cell division GO:0048103 1 0.912
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.813
positive regulation of anoikis GO:2000210 4 0.768
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.748
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.696
cardiac muscle cell contraction GO:0086003 4 0.682
asymmetric neuroblast division GO:0055059 1 0.672
neuroblast division GO:0055057 1 0.658
neuronal stem cell division GO:0036445 1 0.613
actin filament based movement GO:0030048 17 0.608
cardiac muscle cell action potential involved in contraction GO:0086002 21 0.472
catagen GO:0042637 3 0.458
striated muscle contraction GO:0006941 52 0.452
cardiac muscle contraction GO:0060048 34 0.448
neuroblast proliferation GO:0007405 4 0.404
actin mediated cell contraction GO:0070252 12 0.388
action potential GO:0001508 34 0.362
regulation of muscle contraction GO:0006937 45 0.348
intermediate filament based process GO:0045103 17 0.345
muscle contraction GO:0006936 73 0.339
regulation of heart rate GO:0002027 38 0.280
desmosome assembly GO:0002159 4 0.252
intermediate filament organization GO:0045109 10 0.237
regulation of cell differentiation GO:0045595 393 0.230
muscle system process GO:0003012 81 0.227
actin filament based process GO:0030029 224 0.211
epithelium development GO:0060429 227 0.209
Zebrafish
regulation of heart rate by cardiac conduction GO:0086091 19 0.209
regulation of membrane potential GO:0042391 95 0.196
cell division GO:0051301 168 0.181
Human
heart contraction GO:0060047 62 0.178
regulation of cardiac muscle cell contraction GO:0086004 23 0.178
ras protein signal transduction GO:0007265 73 0.178
protein autophosphorylation GO:0046777 123 0.177
epidermal cell differentiation GO:0009913 45 0.174
protein localization to membrane GO:0072657 160 0.168
Human Rat
positive regulation of keratinocyte proliferation GO:0010838 4 0.165
cardiac muscle tissue development GO:0048738 39 0.162
intermediate filament cytoskeleton organization GO:0045104 17 0.160
positive regulation of programmed cell death GO:0043068 249 0.157
single organismal cell cell adhesion GO:0016337 148 0.157
Mouse
cardiac muscle tissue morphogenesis GO:0055008 18 0.148
regulation of cellular component movement GO:0051270 334 0.144
cell communication involved in cardiac conduction GO:0086065 18 0.144
regulation of cardiac muscle contraction GO:0055117 33 0.140
ventricular cardiac muscle cell action potential GO:0086005 15 0.138
epithelial cell differentiation GO:0030855 141 0.138
small gtpase mediated signal transduction GO:0007264 78 0.137
heart process GO:0003015 62 0.127
regulation of heart contraction GO:0008016 50 0.126
cell junction organization GO:0034330 79 0.117
regulation of striated muscle contraction GO:0006942 37 0.110
positive regulation of cell death GO:0010942 263 0.110
cardiac muscle cell cardiac muscle cell adhesion GO:0086042 1 0.109
negative regulation of catagen GO:0051796 1 0.109
plasma membrane organization GO:0007009 115 0.108
Human Rat
regulation of neuron differentiation GO:0045664 70 0.108
circulatory system development GO:0072359 262 0.105
regulation of blood circulation GO:1903522 59 0.104
positive regulation of cell proliferation GO:0008284 301 0.104
cell development GO:0048468 328 0.103
ventricular cardiac muscle tissue development GO:0003229 14 0.102
cardiac conduction GO:0061337 23 0.101
microtubule based process GO:0007017 210 0.100
multicellular organismal signaling GO:0035637 34 0.100
regulation of cytokine production GO:0001817 232 0.094
regulation of muscle system process GO:0090257 53 0.094
positive regulation of cell differentiation GO:0045597 211 0.092
intracellular protein transport GO:0006886 270 0.088
protein localization to adherens junction GO:0071896 2 0.086
regulation of cell development GO:0060284 161 0.079
microtubule cytoskeleton organization GO:0000226 176 0.077
epidermis development GO:0008544 59 0.077
cellular component morphogenesis GO:0032989 314 0.076
desmosome organization GO:0002934 5 0.076
positive regulation of cytoplasmic transport GO:1903651 82 0.075
muscle structure development GO:0061061 98 0.075
cardiac ventricle morphogenesis GO:0003208 20 0.074
cardiac muscle cell action potential GO:0086001 23 0.073
circulatory system process GO:0003013 113 0.073
cellular ketone metabolic process GO:0042180 80 0.069
system process GO:0003008 349 0.069
cytoplasmic transport GO:0016482 379 0.068
anoikis GO:0043276 22 0.068
cell cell junction assembly GO:0007043 25 0.067
single organism cell adhesion GO:0098602 179 0.067
Mouse
skin development GO:0043588 76 0.067
regulation of protein localization GO:0032880 296 0.067
regulation of anatomical structure morphogenesis GO:0022603 286 0.067
positive regulation of apoptotic process GO:0043065 246 0.067
endomembrane system organization GO:0010256 196 0.066
Human Rat
establishment of cell polarity GO:0030010 22 0.066
positive regulation of developmental process GO:0051094 314 0.065
regulation of kinase activity GO:0043549 314 0.064
negative regulation of cellular protein metabolic process GO:0032269 353 0.063
nucleotide catabolic process GO:0009166 408 0.063
Human
amine metabolic process GO:0009308 44 0.063
heart morphogenesis GO:0003007 48 0.063
positive regulation of cellular component organization GO:0051130 376 0.062
peptidyl serine modification GO:0018209 106 0.061
hair follicle morphogenesis GO:0031069 2 0.060
female gamete generation GO:0007292 2 0.060
oogenesis GO:0048477 2 0.059
carbohydrate metabolic process GO:0005975 207 0.059
positive regulation of cell projection organization GO:0031346 64 0.059
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.059
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.058
regulation of wnt signaling pathway GO:0030111 123 0.058
Human
single organism membrane organization GO:0044802 268 0.057
Human Rat
multicellular organismal aging GO:0010259 3 0.057
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.057
regulation of actin filament based process GO:0032970 141 0.056
cellular amino acid metabolic process GO:0006520 116 0.056
positive regulation of neuron projection development GO:0010976 34 0.055
peptidyl serine phosphorylation GO:0018105 101 0.054
photoreceptor cell differentiation GO:0046530 2 0.053
positive regulation of kinase activity GO:0033674 204 0.053
regulation of cell projection organization GO:0031344 107 0.053
regulation of protein stability GO:0031647 87 0.052
cellular macromolecular complex assembly GO:0034622 324 0.052
oxidation reduction process GO:0055114 396 0.052
protein targeting GO:0006605 187 0.051
enzyme linked receptor protein signaling pathway GO:0007167 303 0.051
muscle tissue morphogenesis GO:0060415 19 0.051
cell cell junction organization GO:0045216 69 0.050
posttranscriptional regulation of gene expression GO:0010608 213 0.050
regulation of hair follicle maturation GO:0048819 3 0.048
positive regulation of catabolic process GO:0009896 310 0.048
Human
cell junction assembly GO:0034329 67 0.047
anatomical structure homeostasis GO:0060249 100 0.047
pattern specification process GO:0007389 43 0.046
Zebrafish
cardiac ventricle development GO:0003231 23 0.046
protein modification by small protein conjugation GO:0032446 342 0.045
neuron differentiation GO:0030182 138 0.045
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.045
regulation of system process GO:0044057 101 0.044
neurogenesis GO:0022008 169 0.044
regeneration GO:0031099 4 0.043
cellular lipid metabolic process GO:0044255 303 0.042
negative regulation of protein modification process GO:0031400 200 0.042
directional locomotion GO:0033058 1 0.042
negative regulation of cellular amine metabolic process GO:0033239 3 0.042
negative regulation of cell proliferation GO:0008285 228 0.041
Rat
mitochondrion organization GO:0007005 156 0.041
response to wounding GO:0009611 168 0.041
regulation of intracellular transport GO:0032386 195 0.041
cell morphogenesis GO:0000902 296 0.040
positive regulation of neuron differentiation GO:0045666 40 0.040
regulation of cellular ketone metabolic process GO:0010565 50 0.039
segmentation GO:0035282 4 0.038
cell projection morphogenesis GO:0048858 129 0.038
positive regulation of intracellular protein transport GO:0090316 76 0.038
cell adhesion GO:0007155 325 0.038
Mouse
purine containing compound catabolic process GO:0072523 411 0.038
Human
cell projection organization GO:0030030 252 0.037
innate immune response GO:0045087 178 0.037
epidermis morphogenesis GO:0048730 3 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.036
Human
blood circulation GO:0008015 113 0.036
nervous system development GO:0007399 293 0.036
regulation of cellular amino acid metabolic process GO:0006521 6 0.036
regulation of actin filament based movement GO:1903115 24 0.036
generation of neurons GO:0048699 152 0.035
protein localization to nucleus GO:0034504 136 0.035
lipid metabolic process GO:0006629 381 0.035
positive regulation of protein transport GO:0051222 135 0.035
determination of adult lifespan GO:0008340 2 0.035
regulation of neuron projection development GO:0010975 57 0.035
wound healing GO:0042060 115 0.035
purine nucleoside triphosphate metabolic process GO:0009144 412 0.035
Human
regulation of nervous system development GO:0051960 88 0.035
stem cell division GO:0017145 2 0.034
protein localization to organelle GO:0033365 280 0.034
glycerolipid metabolic process GO:0046486 107 0.034
cation transport GO:0006812 331 0.034
Rat
regulation of cell motility GO:2000145 299 0.034
Rat
regulation of cell morphogenesis GO:0022604 153 0.034
response to growth factor GO:0070848 205 0.034
regulation of nucleocytoplasmic transport GO:0046822 98 0.033
regulation of protein localization to nucleus GO:1900180 85 0.033
ion transmembrane transport GO:0034220 338 0.033
Rat
negative regulation of protein metabolic process GO:0051248 391 0.033
bundle of his cell to purkinje myocyte communication GO:0086069 8 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
Human
positive regulation of nucleoside metabolic process GO:0045979 186 0.032
Human
positive regulation of cellular catabolic process GO:0031331 284 0.032
Human
protein maturation GO:0051604 233 0.032
positive regulation of protein localization to nucleus GO:1900182 48 0.032
response to cytokine GO:0034097 232 0.032
positive regulation of neurogenesis GO:0050769 49 0.031
single organism cellular localization GO:1902580 332 0.031
Human Rat
regulation of proteolysis GO:0030162 293 0.031
regulation of rho protein signal transduction GO:0035023 79 0.031
Human
guanosine containing compound metabolic process GO:1901068 244 0.031
Human
biological adhesion GO:0022610 331 0.030
Mouse
immune response GO:0006955 307 0.030
blastoderm segmentation GO:0007350 2 0.030
negative regulation of cell death GO:0060548 345 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
cell fate commitment GO:0045165 27 0.030
cation transmembrane transport GO:0098655 238 0.030
Rat
nuclear transport GO:0051169 179 0.030
establishment of protein localization to organelle GO:0072594 172 0.030
organophosphate catabolic process GO:0046434 430 0.029
Human
canonical wnt signaling pathway GO:0060070 116 0.029
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.029
Human
positive regulation of protein phosphorylation GO:0001934 313 0.028
cell morphogenesis involved in differentiation GO:0000904 144 0.028
dephosphorylation GO:0016311 209 0.028
negative regulation of cellular component organization GO:0051129 235 0.028
peptidyl tyrosine phosphorylation GO:0018108 170 0.028
protein localization to cell junction GO:1902414 3 0.028
epithelial cell migration GO:0010631 119 0.028
purine nucleoside catabolic process GO:0006152 398 0.028
Human
stem cell proliferation GO:0072089 25 0.028
cell part morphogenesis GO:0032990 137 0.027
lung alveolus development GO:0048286 4 0.027
metal ion transport GO:0030001 272 0.027
Rat
chemical homeostasis GO:0048878 306 0.027
Rat
positive regulation of gtp catabolic process GO:0033126 166 0.027
Human
regulation of gtpase activity GO:0043087 180 0.026
Human
endothelial cell migration GO:0043542 86 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
protein dephosphorylation GO:0006470 81 0.026
protein catabolic process GO:0030163 325 0.026
memory GO:0007613 3 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
Human
single organism reproductive process GO:0044702 98 0.026
regulation of anoikis GO:2000209 19 0.026
inorganic ion transmembrane transport GO:0098660 231 0.026
Rat
regulation of cell migration GO:0030334 289 0.026
Rat
post embryonic development GO:0009791 2 0.025
monocarboxylic acid metabolic process GO:0032787 185 0.025
defense response GO:0006952 315 0.025
microtubule bundle formation GO:0001578 15 0.025
regulation of neurogenesis GO:0050767 82 0.025
anterior posterior axis specification GO:0009948 2 0.025
protein ubiquitination GO:0016567 314 0.024
oocyte development GO:0048599 1 0.024
motor neuron axon guidance GO:0008045 2 0.024
golgi to plasma membrane cftr protein transport GO:0043000 1 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.024
Human
tripartite regional subdivision GO:0007351 2 0.024
transmembrane transport GO:0055085 399 0.024
Rat
cellular response to oxygen containing compound GO:1901701 276 0.024
negative regulation of transforming growth factor beta production GO:0071635 4 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
Rat
cellular amine metabolic process GO:0044106 41 0.023
oocyte differentiation GO:0009994 2 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
lipid catabolic process GO:0016042 84 0.023
epithelium migration GO:0090132 119 0.023
positive regulation of transport GO:0051050 336 0.023
Rat
regulation of smooth muscle cell proliferation GO:0048660 28 0.023
single organism nuclear import GO:1902593 104 0.023
intermediate filament bundle assembly GO:0045110 5 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
Human
negative regulation of phosphorylation GO:0042326 174 0.023
regulation of protein complex assembly GO:0043254 147 0.023
muscle tissue development GO:0060537 62 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
Human
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.023
positive regulation of mapk cascade GO:0043410 190 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
Human
establishment or maintenance of cell polarity GO:0007163 31 0.022
hair follicle maturation GO:0048820 3 0.022
regulation of mitotic cell cycle GO:0007346 189 0.022
developmental process involved in reproduction GO:0003006 66 0.022
potassium ion transmembrane transport GO:0071805 60 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.022
tissue morphogenesis GO:0048729 96 0.022
reproductive process GO:0022414 106 0.021
organ morphogenesis GO:0009887 147 0.021
nitrogen compound transport GO:0071705 191 0.021
glycoprotein metabolic process GO:0009100 110 0.021
positive regulation of ras gtpase activity GO:0032320 117 0.021
Human
hair cycle GO:0042633 28 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
cardiovascular system development GO:0072358 262 0.021
muscle organ development GO:0007517 56 0.021
inorganic cation transmembrane transport GO:0098662 194 0.021
Rat
nucleoside catabolic process GO:0009164 408 0.021
Human
keratinocyte activation GO:0032980 1 0.021
regulation of protein catabolic process GO:0042176 155 0.021
membrane organization GO:0061024 292 0.021
Human Rat
cellular potassium ion transport GO:0071804 60 0.020
low density lipoprotein particle mediated signaling GO:0055096 1 0.020
golgi vesicle transport GO:0048193 80 0.020
positive regulation of locomotion GO:0040017 186 0.020
regulation of mapk cascade GO:0043408 262 0.020
regulation of canonical wnt signaling pathway GO:0060828 88 0.020
Human
morphogenesis of a polarized epithelium GO:0001738 3 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
specification of organ identity GO:0010092 3 0.020
neuron projection development GO:0031175 106 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.020
i kappab kinase nf kappab signaling GO:0007249 166 0.020
neuron development GO:0048666 113 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
cellular response to endogenous stimulus GO:0071495 336 0.019
lipid biosynthetic process GO:0008610 177 0.019
ribonucleotide catabolic process GO:0009261 405 0.019
Human
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
Human
lipoprotein particle mediated signaling GO:0055095 1 0.019
organic hydroxy compound metabolic process GO:1901615 147 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
cellular protein catabolic process GO:0044257 261 0.019
regulation of melanin biosynthetic process GO:0048021 1 0.019
response to hormone GO:0009725 175 0.019
positive regulation of cell motility GO:2000147 177 0.019
establishment of skin barrier GO:0061436 5 0.019
establishment of protein localization to membrane GO:0090150 121 0.018
Human
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.018
keratinocyte proliferation GO:0043616 17 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
Human
tissue regeneration GO:0042246 3 0.018
regulation of melanosome transport GO:1902908 1 0.018
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.018
secondary metabolite biosynthetic process GO:0044550 2 0.018
reproductive structure development GO:0048608 55 0.018
positive regulation of wnt signaling pathway GO:0030177 54 0.018
positive regulation of proteolysis GO:0045862 142 0.018
protein localization to plasma membrane GO:0072659 93 0.018
Human Rat
morphogenesis of an epithelium GO:0002009 60 0.018
Zebrafish
regulation of gtp catabolic process GO:0033124 180 0.018
Human
mapk cascade GO:0000165 288 0.018
heart development GO:0007507 95 0.018
mitotic cell cycle GO:0000278 326 0.018
neuromuscular junction development GO:0007528 3 0.018
response to tumor necrosis factor GO:0034612 76 0.017
cellular protein complex assembly GO:0043623 188 0.017
positive regulation of organelle organization GO:0010638 195 0.017
cytokine mediated signaling pathway GO:0019221 109 0.017
regulation of transferase activity GO:0051338 355 0.017
regulation of cell cell adhesion GO:0022407 57 0.017
endodermal cell fate specification GO:0001714 4 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
blood vessel morphogenesis GO:0048514 162 0.017
sodium ion transmembrane transport GO:0035725 59 0.017
Rat
response to transforming growth factor beta GO:0071559 94 0.017
response to lipid GO:0033993 206 0.017
monovalent inorganic cation transport GO:0015672 128 0.017
Rat
cell substrate adhesion GO:0031589 132 0.017
regulation of protein kinase activity GO:0045859 289 0.017
chromatin modification GO:0016568 298 0.017
protein complex disassembly GO:0043241 52 0.017
protein targeting to nucleus GO:0044744 104 0.017
anterior posterior axis specification embryo GO:0008595 2 0.017
mitotic cell cycle process GO:1903047 286 0.017
organelle assembly GO:0070925 176 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.016
amide transport GO:0042886 76 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.016
atrioventricular valve development GO:0003171 3 0.016
regulation of map kinase activity GO:0043405 108 0.016
spermatid differentiation GO:0048515 4 0.016
peptide transport GO:0015833 74 0.016
regulation of epithelial cell proliferation GO:0050678 113 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
sulfur compound metabolic process GO:0006790 101 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
regulation of protein transport GO:0051223 213 0.016
response to other organism GO:0051707 261 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
Human
cellular response to tumor necrosis factor GO:0071356 63 0.016
regulation of synaptic plasticity GO:0048167 3 0.016
negative regulation of transferase activity GO:0051348 124 0.016
response to low density lipoprotein particle GO:0055098 4 0.016
regulation of cell cycle process GO:0010564 266 0.015
Human
spermatid development GO:0007286 4 0.015
regulation of cellular response to stress GO:0080135 244 0.015
apoptotic signaling pathway GO:0097190 268 0.015
positive regulation of protein catabolic process GO:0045732 75 0.015
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.015
epiboly involved in gastrulation with mouth forming second GO:0055113 1 0.015
protein dna complex assembly GO:0065004 64 0.015
smad protein complex assembly GO:0007183 12 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.015
convergent extension involved in gastrulation GO:0060027 1 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
Human
regulation of endopeptidase activity GO:0052548 170 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
cellular component disassembly GO:0022411 92 0.015
divalent inorganic cation transport GO:0072511 158 0.015
regulation of epidermis development GO:0045682 19 0.015
epithelial cell proliferation GO:0050673 128 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
behavior GO:0007610 112 0.015
negative regulation of locomotion GO:0040013 118 0.015
Rat
positive regulation of transferase activity GO:0051347 227 0.015
hindbrain development GO:0030902 3 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
Human
ossification GO:0001503 121 0.015
small molecule biosynthetic process GO:0044283 157 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
metal ion homeostasis GO:0055065 169 0.014
negative regulation of hair follicle development GO:0051799 1 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
Human
intracellular receptor signaling pathway GO:0030522 104 0.014
keratinocyte differentiation GO:0030216 36 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.014
tissue homeostasis GO:0001894 63 0.014
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.014
regulation of metal ion transport GO:0010959 120 0.014
Rat
transcription factor import into nucleus GO:0042991 40 0.014
organ formation GO:0048645 3 0.014
regulation of multi organism process GO:0043900 157 0.014
transforming growth factor beta production GO:0071604 14 0.014
regulation of locomotion GO:0040012 329 0.014
Rat
regulation of behavior GO:0050795 82 0.014
positive regulation of cell division GO:0051781 59 0.014
Human
response to light stimulus GO:0009416 87 0.014
regulation of ion homeostasis GO:2000021 73 0.014
adult locomotory behavior GO:0008344 1 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
macromolecular complex disassembly GO:0032984 60 0.014
peptide cross linking GO:0018149 12 0.014
cellular homeostasis GO:0019725 196 0.014
regulation of cardiac muscle tissue growth GO:0055021 4 0.014
cellular response to dna damage stimulus GO:0006974 379 0.013
response to estrogen GO:0043627 47 0.013
positive regulation of intracellular transport GO:0032388 104 0.013
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.013
regulation of rho gtpase activity GO:0032319 66 0.013
Human
locomotory behavior GO:0007626 1 0.013
regulation of ion transmembrane transport GO:0034765 132 0.013
primary neural tube formation GO:0014020 3 0.013
vasculature development GO:0001944 181 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
embryonic placenta development GO:0001892 1 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
Human
response to radiation GO:0009314 151 0.013
response to oxygen containing compound GO:1901700 369 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
axis elongation GO:0003401 4 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.013
endosomal transport GO:0016197 129 0.013
regulation of immune response GO:0050776 201 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
long term memory GO:0007616 2 0.013
regulation of erk1 and erk2 cascade GO:0070372 99 0.013
meiosis i GO:0007127 4 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
Human
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 19 0.013
cellular polysaccharide metabolic process GO:0044264 27 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
gtp catabolic process GO:0006184 237 0.013
Human
negative regulation of protein phosphorylation GO:0001933 140 0.013
establishment of planar polarity GO:0001736 3 0.013
embryonic pattern specification GO:0009880 5 0.013
positive regulation of map kinase activity GO:0043406 80 0.012
response to hypoxia GO:0001666 96 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
blood vessel development GO:0001568 172 0.012
monocarboxylic acid biosynthetic process GO:0072330 67 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
organic hydroxy compound biosynthetic process GO:1901617 71 0.012
negative regulation of cell cycle GO:0045786 193 0.012
embryo development GO:0009790 123 0.012
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 186 0.012
fatty acid metabolic process GO:0006631 115 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
regulation of cell division GO:0051302 116 0.012
Human
response to biotic stimulus GO:0009607 276 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
positive regulation of neural precursor cell proliferation GO:2000179 2 0.012

PKP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 114 0.905
musculoskeletal system disease DOID:17 223 0.905
heart disease DOID:114 68 0.888
myopathy DOID:423 104 0.888
muscle tissue disease DOID:66 113 0.888
intrinsic cardiomyopathy DOID:0060036 50 0.888
cardiovascular system disease DOID:1287 106 0.888
cardiomyopathy DOID:0050700 50 0.888
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 9 0.213
disease of metabolism DOID:0014667 295 0.029
nervous system disease DOID:863 431 0.020
sensory system disease DOID:0050155 203 0.020
dilated cardiomyopathy DOID:12930 32 0.018
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.015
retinal disease DOID:5679 118 0.014
inherited metabolic disorder DOID:655 242 0.012
disease of cellular proliferation DOID:14566 174 0.012
cancer DOID:162 167 0.012
organ system cancer DOID:0050686 164 0.012