Homo sapiens

135 known processes

PKP4

plakophilin 4

(Aliases: FLJ31261,p0071,FLJ42243)

PKP4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein localization to adherens junction GO:0071896 2 0.681
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.636
amyloid precursor protein catabolic process GO:0042987 12 0.609
pharynx development GO:0060465 1 0.575
heart morphogenesis GO:0003007 48 0.560
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.558
cerebral cortex cell migration GO:0021795 3 0.499
rho protein signal transduction GO:0007266 26 0.464
regulation of cellular amino acid metabolic process GO:0006521 6 0.417
positive regulation of gtp catabolic process GO:0033126 166 0.407
protein localization to cell junction GO:1902414 3 0.407
positive regulation of ras gtpase activity GO:0032320 117 0.388
cellular amino acid metabolic process GO:0006520 116 0.387
beta amyloid formation GO:0034205 7 0.376
regulation of nucleoside metabolic process GO:0009118 209 0.355
embryonic digestive tract morphogenesis GO:0048557 2 0.354
actin filament based process GO:0030029 224 0.347
Worm
amine metabolic process GO:0009308 44 0.342
cerebral cortex neuron differentiation GO:0021895 1 0.337
nucleoside triphosphate catabolic process GO:0009143 394 0.337
regulation of purine nucleotide catabolic process GO:0033121 205 0.337
intermediate filament cytoskeleton organization GO:0045104 17 0.333
Human
brain morphogenesis GO:0048854 1 0.331
embryonic epithelial tube formation GO:0001838 4 0.321
guanosine containing compound metabolic process GO:1901068 244 0.314
cardiac muscle cell contraction GO:0086003 4 0.310
inorganic ion transmembrane transport GO:0098660 231 0.308
ion transmembrane transport GO:0034220 338 0.302
signal transduction by phosphorylation GO:0023014 297 0.302
cell cell junction organization GO:0045216 69 0.301
Human Mouse
glycoprotein biosynthetic process GO:0009101 91 0.296
cell junction assembly GO:0034329 67 0.291
Human Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.289
cation transport GO:0006812 331 0.286
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.281
notch receptor processing GO:0007220 2 0.281
nucleoside phosphate catabolic process GO:1901292 412 0.275
ribonucleotide catabolic process GO:0009261 405 0.275
glycosyl compound catabolic process GO:1901658 413 0.268
desmosome assembly GO:0002159 4 0.262
Human
developmental programmed cell death GO:0010623 3 0.258
cation transmembrane transport GO:0098655 238 0.246
cell projection organization GO:0030030 252 0.238
regulation of rho gtpase activity GO:0032319 66 0.236
positive regulation of coagulation GO:0050820 11 0.234
regulation of rho protein signal transduction GO:0035023 79 0.229
mitotic cell cycle GO:0000278 326 0.228
nucleotide catabolic process GO:0009166 408 0.227
neural tube formation GO:0001841 3 0.225
guanosine containing compound catabolic process GO:1901069 239 0.224
regulation of nucleotide catabolic process GO:0030811 205 0.223
gtp catabolic process GO:0006184 237 0.219
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.218
single organism cell adhesion GO:0098602 179 0.208
positive regulation of hydrolase activity GO:0051345 331 0.203
inorganic cation transmembrane transport GO:0098662 194 0.197
small gtpase mediated signal transduction GO:0007264 78 0.197
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.196
nervous system development GO:0007399 293 0.195
organ morphogenesis GO:0009887 147 0.191
Human
negative regulation of axonogenesis GO:0050771 4 0.188
ribonucleoside catabolic process GO:0042454 406 0.188
purine containing compound catabolic process GO:0072523 411 0.187
biological adhesion GO:0022610 331 0.181
female gamete generation GO:0007292 2 0.178
regulation of heart rate by cardiac conduction GO:0086091 19 0.171
Human
positive regulation of nucleotide catabolic process GO:0030813 185 0.170
organophosphate catabolic process GO:0046434 430 0.167
cardiac muscle cell action potential involved in contraction GO:0086002 21 0.164
Human
cell morphogenesis involved in differentiation GO:0000904 144 0.164
neurotransmitter secretion GO:0007269 4 0.161
ribonucleoside triphosphate metabolic process GO:0009199 412 0.161
cell activation GO:0001775 213 0.160
protein glycosylation GO:0006486 62 0.159
nucleoside catabolic process GO:0009164 408 0.159
memory GO:0007613 3 0.156
positive regulation of rho gtpase activity GO:0032321 56 0.155
single organismal cell cell adhesion GO:0016337 148 0.152
regulation of cellular amine metabolic process GO:0033238 11 0.150
cardiovascular system development GO:0072358 262 0.147
Human
determination of adult lifespan GO:0008340 2 0.146
pituitary gland development GO:0021983 2 0.146
regulation of gtpase activity GO:0043087 180 0.145
regulation of cell differentiation GO:0045595 393 0.144
Human
establishment or maintenance of monopolar cell polarity GO:0061339 1 0.144
positive regulation of cellular catabolic process GO:0031331 284 0.140
positive regulation of nucleotide metabolic process GO:0045981 230 0.138
regulation of small gtpase mediated signal transduction GO:0051056 156 0.137
ras protein signal transduction GO:0007265 73 0.136
regulation of cell motility GO:2000145 299 0.136
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.136
keratinocyte differentiation GO:0030216 36 0.132
neural tube closure GO:0001843 3 0.132
regulation of purine nucleotide metabolic process GO:1900542 264 0.130
purine nucleoside catabolic process GO:0006152 398 0.129
somitogenesis GO:0001756 2 0.129
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.127
apoptotic process involved in morphogenesis GO:0060561 3 0.127
neural tube patterning GO:0021532 2 0.127
purine ribonucleoside catabolic process GO:0046130 398 0.127
neuron projection development GO:0031175 106 0.126
cell adhesion GO:0007155 325 0.125
regulation of cell cycle GO:0051726 393 0.125
glycosylation GO:0070085 71 0.121
positive regulation of programmed cell death GO:0043068 249 0.121
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.120
motor neuron axon guidance GO:0008045 2 0.119
chemical homeostasis GO:0048878 306 0.118
amyloid precursor protein metabolic process GO:0042982 17 0.116
hair follicle maturation GO:0048820 3 0.116
transmembrane transport GO:0055085 399 0.114
embryonic forelimb morphogenesis GO:0035115 4 0.113
regulation of mitotic cell cycle GO:0007346 189 0.112
primary neural tube formation GO:0014020 3 0.110
regulation of cytoskeleton organization GO:0051493 177 0.110
Worm
neuron differentiation GO:0030182 138 0.109
purine nucleotide catabolic process GO:0006195 405 0.108
epithelium development GO:0060429 227 0.105
carbohydrate derivative biosynthetic process GO:1901137 207 0.104
positive regulation of kinase activity GO:0033674 204 0.104
establishment of monopolar cell polarity GO:0061162 1 0.104
epithelial cell proliferation GO:0050673 128 0.103
blood vessel development GO:0001568 172 0.103
receptor metabolic process GO:0043112 81 0.103
receptor recycling GO:0001881 15 0.101
regulation of ras gtpase activity GO:0032318 128 0.101
regulation of cell projection organization GO:0031344 107 0.099
multicellular organismal aging GO:0010259 3 0.097
secretion by cell GO:0032940 226 0.097
cell cell junction assembly GO:0007043 25 0.096
Human Mouse
negative regulation of cellular amine metabolic process GO:0033239 3 0.096
regulation of cell development GO:0060284 161 0.096
copper ion import GO:0015677 1 0.095
regulation of muscle system process GO:0090257 53 0.095
Human
segmentation GO:0035282 4 0.095
negative regulation of cellular component organization GO:0051129 235 0.093
synaptic vesicle exocytosis GO:0016079 3 0.093
thymus development GO:0048538 3 0.092
action potential GO:0001508 34 0.092
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.091
regulation of cardiac muscle cell contraction GO:0086004 23 0.090
Human
regulation of nucleotide metabolic process GO:0006140 269 0.090
peptidyl tyrosine phosphorylation GO:0018108 170 0.090
epithelial cell differentiation GO:0030855 141 0.090
negative regulation of cellular protein metabolic process GO:0032269 353 0.089
establishment of apical basal cell polarity GO:0035089 1 0.087
ribonucleoside triphosphate catabolic process GO:0009203 391 0.087
tissue morphogenesis GO:0048729 96 0.086
Human
neurogenesis GO:0022008 169 0.086
purine nucleoside triphosphate catabolic process GO:0009146 392 0.086
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.086
negative regulation of catabolic process GO:0009895 104 0.085
regulation of protein transport GO:0051223 213 0.085
epithelial tube morphogenesis GO:0060562 38 0.084
positive regulation of nucleoside metabolic process GO:0045979 186 0.084
organic anion transport GO:0015711 103 0.083
cellular response to dna damage stimulus GO:0006974 379 0.083
carbohydrate metabolic process GO:0005975 207 0.083
cellular ketone metabolic process GO:0042180 80 0.082
positive regulation of cellular component organization GO:0051130 376 0.082
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.082
actin filament based movement GO:0030048 17 0.081
cardiac muscle cell action potential GO:0086001 23 0.081
Human
organic hydroxy compound transport GO:0015850 63 0.081
single organism carbohydrate metabolic process GO:0044723 193 0.080
cardiac muscle tissue development GO:0048738 39 0.075
Human
nephron tubule formation GO:0072079 1 0.075
morphogenesis of an epithelium GO:0002009 60 0.075
intermediate filament based process GO:0045103 17 0.075
Human
taxis GO:0042330 157 0.074
mapk cascade GO:0000165 288 0.074
proteoglycan metabolic process GO:0006029 29 0.073
protein ubiquitination GO:0016567 314 0.073
cell projection morphogenesis GO:0048858 129 0.073
positive regulation of cell motility GO:2000147 177 0.072
positive regulation of catabolic process GO:0009896 310 0.071
muscle system process GO:0003012 81 0.071
tube development GO:0035295 125 0.071
cardiac chamber morphogenesis GO:0003206 26 0.071
Human
system process GO:0003008 349 0.071
Human
skin development GO:0043588 76 0.070
regulation of actin filament based process GO:0032970 141 0.070
Human Worm
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.069
anion transport GO:0006820 161 0.069
tube closure GO:0060606 3 0.069
regulation of protein serine threonine kinase activity GO:0071900 179 0.067
positive regulation of transport GO:0051050 336 0.067
vesicle targeting GO:0006903 7 0.067
photoreceptor cell differentiation GO:0046530 2 0.066
chemotaxis GO:0006935 157 0.066
cardiac ventricle development GO:0003231 23 0.065
Human
negative regulation of developmental process GO:0051093 247 0.065
Human
regulation of gtp catabolic process GO:0033124 180 0.065
neuromuscular junction development GO:0007528 3 0.064
negative regulation of multicellular organismal process GO:0051241 317 0.064
cell morphogenesis GO:0000902 296 0.063
membrane protein ectodomain proteolysis GO:0006509 33 0.063
positive regulation of receptor recycling GO:0001921 5 0.063
dendritic cell differentiation GO:0097028 13 0.062
actin mediated cell contraction GO:0070252 12 0.062
cerebral cortex radially oriented cell migration GO:0021799 1 0.061
post embryonic development GO:0009791 2 0.061
cellular divalent inorganic cation homeostasis GO:0072503 128 0.060
positive regulation of gtpase activity GO:0043547 166 0.060
organelle assembly GO:0070925 176 0.059
regulation of membrane potential GO:0042391 95 0.059
Human
transition metal ion transport GO:0000041 23 0.058
regulation of cellular component movement GO:0051270 334 0.058
Human
anatomical structure homeostasis GO:0060249 100 0.058
regulation of ras protein signal transduction GO:0046578 155 0.058
regulation of epithelial cell proliferation GO:0050678 113 0.058
regulation of locomotion GO:0040012 329 0.058
regulation of neuron migration GO:2001222 3 0.058
calcium ion transmembrane transport GO:0070588 76 0.057
regulation of proteolysis GO:0030162 293 0.057
negative regulation of catagen GO:0051796 1 0.057
forelimb morphogenesis GO:0035136 4 0.056
nucleoside triphosphate metabolic process GO:0009141 422 0.056
single organism nuclear import GO:1902593 104 0.056
positive regulation of cytoskeleton organization GO:0051495 83 0.056
glycoprotein metabolic process GO:0009100 110 0.055
associative learning GO:0008306 1 0.055
peptide metabolic process GO:0006518 51 0.055
negative regulation of protein metabolic process GO:0051248 391 0.055
myeloid dendritic cell activation GO:0001773 4 0.055
regulation of protein processing GO:0070613 150 0.055
regulation of cell morphogenesis GO:0022604 153 0.054
regulation of glutamine family amino acid metabolic process GO:0000820 2 0.054
muscle organ development GO:0007517 56 0.054
Human
mitotic cell cycle process GO:1903047 286 0.054
rna processing GO:0006396 255 0.054
microtubule cytoskeleton organization GO:0000226 176 0.054
nitrogen compound transport GO:0071705 191 0.054
cardiac chamber development GO:0003205 30 0.053
Human
metal ion transport GO:0030001 272 0.052
neural tube development GO:0021915 9 0.052
regulation of receptor recycling GO:0001919 10 0.052
cell junction organization GO:0034330 79 0.051
Human Mouse
protein processing GO:0016485 226 0.051
organic acid transport GO:0015849 65 0.050
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.050
negative regulation of proteolysis GO:0045861 132 0.050
macromolecule glycosylation GO:0043413 63 0.050
ion homeostasis GO:0050801 230 0.050
amino acid transport GO:0006865 28 0.050
regulation of transferase activity GO:0051338 355 0.050
positive regulation of transferase activity GO:0051347 227 0.050
muscle tissue development GO:0060537 62 0.049
Human
neuroblast proliferation GO:0007405 4 0.049
negative regulation of cell motility GO:2000146 104 0.049
positive regulation of developmental process GO:0051094 314 0.049
cellular component morphogenesis GO:0032989 314 0.048
cilium organization GO:0044782 68 0.048
gastrulation with mouth forming second GO:0001702 1 0.048
vasculature development GO:0001944 181 0.048
locomotory behavior GO:0007626 1 0.048
positive regulation of rac gtpase activity GO:0032855 31 0.048
cytokinesis GO:0000910 96 0.048
negative regulation of cell fate specification GO:0009996 3 0.047
endodermal cell fate specification GO:0001714 4 0.047
peptidyl tyrosine modification GO:0018212 170 0.047
negative regulation of protein processing GO:0010955 142 0.046
hair follicle morphogenesis GO:0031069 2 0.046
mating GO:0007618 1 0.046
cellular homeostasis GO:0019725 196 0.046
negative regulation of cellular catabolic process GO:0031330 83 0.046
carboxylic acid transport GO:0046942 63 0.046
positive regulation of cellular component movement GO:0051272 181 0.046
divalent metal ion transport GO:0070838 152 0.046
cation homeostasis GO:0055080 189 0.045
vacuole organization GO:0007033 44 0.045
nuclear transport GO:0051169 179 0.045
neurological system process GO:0050877 163 0.045
cell development GO:0048468 328 0.045
activation of mapkk activity GO:0000186 18 0.045
regulation of anatomical structure morphogenesis GO:0022603 286 0.045
autophagy GO:0006914 88 0.044
macroautophagy GO:0016236 39 0.044
protein maturation GO:0051604 233 0.044
cell migration involved in gastrulation GO:0042074 1 0.044
blood circulation GO:0008015 113 0.044
Human
regulation of mapk cascade GO:0043408 262 0.044
cellular metal ion homeostasis GO:0006875 146 0.044
negative regulation of phosphorus metabolic process GO:0010563 267 0.043
activation of protein kinase activity GO:0032147 90 0.043
positive regulation of apoptotic process GO:0043065 246 0.043
embryonic digestive tract development GO:0048566 10 0.043
regulation of protein complex assembly GO:0043254 147 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.042
regulation of cardioblast differentiation GO:0051890 4 0.042
protein localization to membrane GO:0072657 160 0.042
Human
circulatory system development GO:0072359 262 0.042
Human
proteoglycan biosynthetic process GO:0030166 20 0.042
cell fate determination GO:0001709 3 0.042
negative regulation of protein phosphorylation GO:0001933 140 0.041
positive regulation of organelle organization GO:0010638 195 0.041
organelle fission GO:0048285 149 0.041
intracellular protein transport GO:0006886 270 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.041
enzyme linked receptor protein signaling pathway GO:0007167 303 0.041
muscle structure development GO:0061061 98 0.040
Human
negative regulation of phosphorylation GO:0042326 174 0.040
membrane organization GO:0061024 292 0.040
Human
cellular response to endogenous stimulus GO:0071495 336 0.040
vesicle mediated transport GO:0016192 371 0.040
negative regulation of protein modification process GO:0031400 200 0.040
heart development GO:0007507 95 0.039
Human
regulation of actin cytoskeleton organization GO:0032956 116 0.039
Worm
cellular response to external stimulus GO:0071496 111 0.039
cell part morphogenesis GO:0032990 137 0.039
regulation of neurogenesis GO:0050767 82 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.038
positive regulation of cell cycle process GO:0090068 106 0.038
regulation of synaptic plasticity GO:0048167 3 0.038
regulation of endopeptidase activity GO:0052548 170 0.038
head development GO:0060322 108 0.038
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.038
positive regulation of cell death GO:0010942 263 0.038
protein targeting to nucleus GO:0044744 104 0.038
cellular response to starvation GO:0009267 58 0.038
chordate embryonic development GO:0043009 34 0.038
cerebral cortex radial glia guided migration GO:0021801 1 0.038
skeletal system development GO:0001501 79 0.037
negative regulation of embryonic development GO:0045992 4 0.037
positive regulation of keratinocyte proliferation GO:0010838 4 0.037
cellular calcium ion homeostasis GO:0006874 117 0.037
regulation of cell migration GO:0030334 289 0.036
coagulation GO:0050817 78 0.036
regulation of heart rate GO:0002027 38 0.036
Human
regulation of protein maturation GO:1903317 150 0.036
positive regulation of protein kinase activity GO:0045860 190 0.035
peptidyl serine phosphorylation GO:0018105 101 0.035
cardioblast cell fate specification GO:0042685 1 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
anterior posterior axis specification GO:0009948 2 0.035
regulation of kinase activity GO:0043549 314 0.035
positive regulation of phosphorylation GO:0042327 394 0.035
immune system development GO:0002520 195 0.035
negative regulation of protein catabolic process GO:0042177 59 0.035
negative regulation of cell death GO:0060548 345 0.034
negative regulation of cell migration GO:0030336 102 0.034
hematopoietic or lymphoid organ development GO:0048534 186 0.034
cell cell signaling GO:0007267 155 0.034
Human
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.034
Human
regulation of protein localization GO:0032880 296 0.034
Worm
regulation of protein catabolic process GO:0042176 155 0.034
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.033
brain development GO:0007420 97 0.033
cellular response to nutrient levels GO:0031669 69 0.033
response to extracellular stimulus GO:0009991 85 0.033
ectoderm development GO:0007398 3 0.033
regulation of endothelial cell differentiation GO:0045601 4 0.033
negative regulation of protein transport GO:0051224 75 0.033
positive regulation of cell migration GO:0030335 172 0.033
bundle of his cell to purkinje myocyte communication GO:0086069 8 0.032
Human
posttranscriptional regulation of gene expression GO:0010608 213 0.032
purine ribonucleotide catabolic process GO:0009154 404 0.032
behavioral response to ethanol GO:0048149 2 0.032
autophagic vacuole assembly GO:0000045 19 0.032
regulation of cellular protein catabolic process GO:1903362 96 0.032
t cell differentiation in thymus GO:0033077 4 0.032
negative regulation of epithelial cell proliferation GO:0050680 48 0.032
embryonic organ development GO:0048568 36 0.032
cellular macromolecular complex assembly GO:0034622 324 0.031
positive chemotaxis GO:0050918 33 0.031
negative regulation of protein kinase activity GO:0006469 98 0.031
telencephalon cell migration GO:0022029 4 0.031
oocyte development GO:0048599 1 0.031
negative regulation of transport GO:0051051 176 0.031
proteasomal protein catabolic process GO:0010498 176 0.030
mitotic cell cycle phase transition GO:0044772 162 0.030
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.030
Human
positive regulation of locomotion GO:0040017 186 0.030
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.030
cellular amine metabolic process GO:0044106 41 0.030
mitotic nuclear division GO:0007067 119 0.030
regulation of intracellular transport GO:0032386 195 0.030
response to oxygen containing compound GO:1901700 369 0.030
embryonic hindlimb morphogenesis GO:0035116 2 0.030
negative regulation of cellular protein catabolic process GO:1903363 38 0.030
cellular macromolecule catabolic process GO:0044265 380 0.030
calcium ion homeostasis GO:0055074 122 0.030
glutamate metabolic process GO:0006536 10 0.030
organelle localization GO:0051640 84 0.029
negative regulation of wnt signaling pathway GO:0030178 69 0.029
Human
cerebral cortex development GO:0021987 10 0.029
cellular amide metabolic process GO:0043603 69 0.029
oocyte differentiation GO:0009994 2 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
membrane protein proteolysis GO:0033619 38 0.029
response to nitrogen compound GO:1901698 184 0.029
catagen GO:0042637 3 0.028
positive regulation of protein phosphorylation GO:0001934 313 0.028
adenosine metabolic process GO:0046085 4 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.028
regulation of cell adhesion GO:0030155 166 0.028
determination of bilateral symmetry GO:0009855 15 0.028
regulation of heart induction GO:0090381 2 0.028
lymphangiogenesis GO:0001946 7 0.028
divalent inorganic cation homeostasis GO:0072507 136 0.028
engulfment of apoptotic cell GO:0043652 2 0.028
hair cycle phase GO:0044851 3 0.028
negative regulation of cell cycle GO:0045786 193 0.028
hair cycle process GO:0022405 12 0.027
protein autophosphorylation GO:0046777 123 0.027
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 7 0.027
adult locomotory behavior GO:0008344 1 0.027
immune response GO:0006955 307 0.027
protein modification by small protein conjugation GO:0032446 342 0.027
canonical wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition GO:0044334 2 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
hindlimb morphogenesis GO:0035137 2 0.027
epidermal cell differentiation GO:0009913 45 0.027
regulation of mitotic cell cycle phase transition GO:1901990 118 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.027
myeloid leukocyte activation GO:0002274 34 0.026
cardioblast cell fate commitment GO:0042684 1 0.026
actin cytoskeleton organization GO:0030036 207 0.026
Worm
regulation of heart morphogenesis GO:2000826 4 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.026
cellular chemical homeostasis GO:0055082 180 0.026
cellular ion homeostasis GO:0006873 168 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.026
regulation of system process GO:0044057 101 0.026
Human
specification of symmetry GO:0009799 16 0.025
maintenance of location in cell GO:0051651 62 0.025
somatic stem cell maintenance GO:0035019 4 0.025
blastocyst development GO:0001824 3 0.025
exocytosis GO:0006887 71 0.025
keratinization GO:0031424 2 0.025
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.024
negative regulation of mitotic cell cycle GO:0045930 102 0.024
neurotransmitter transport GO:0006836 10 0.024
cellular response to oxygen containing compound GO:1901701 276 0.024
regulation of muscle contraction GO:0006937 45 0.024
Human
positive regulation of protein transport GO:0051222 135 0.024
peripheral nervous system development GO:0007422 2 0.024
endodermal cell fate commitment GO:0001711 4 0.024
sulfur compound biosynthetic process GO:0044272 38 0.024
lipid metabolic process GO:0006629 381 0.024
monovalent inorganic cation transport GO:0015672 128 0.024
organ induction GO:0001759 4 0.024
response to abiotic stimulus GO:0009628 336 0.024
histone modification GO:0016570 251 0.024
lymphocyte activation GO:0046649 133 0.024
regulation of peptidase activity GO:0052547 180 0.024
nephron tubule epithelial cell differentiation GO:0072160 3 0.023
response to growth factor GO:0070848 205 0.023
protein import into nucleus GO:0006606 104 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
long term memory GO:0007616 2 0.023
response to starvation GO:0042594 59 0.023
negative regulation of glial cell differentiation GO:0045686 1 0.023
striated muscle tissue development GO:0014706 59 0.023
Human
beta amyloid metabolic process GO:0050435 12 0.023
reproductive structure development GO:0048608 55 0.023
peptidyl serine modification GO:0018209 106 0.023
cellular response to extracellular stimulus GO:0031668 72 0.023
modification dependent macromolecule catabolic process GO:0043632 212 0.023
negative regulation of gliogenesis GO:0014014 3 0.022
prostate gland development GO:0030850 3 0.022
neuronal action potential GO:0019228 9 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022

PKP4 disease predictions

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 104 0.838
Human
muscular disease DOID:0080000 114 0.838
Human
heart disease DOID:114 68 0.838
Human
cardiomyopathy DOID:0050700 50 0.838
Human
cardiovascular system disease DOID:1287 106 0.838
Human
musculoskeletal system disease DOID:17 223 0.838
Human
muscle tissue disease DOID:66 113 0.838
Human
disease of mental health DOID:150 70 0.562
cognitive disorder DOID:1561 29 0.562
central nervous system disease DOID:331 186 0.519
tauopathy DOID:680 16 0.519
neurodegenerative disease DOID:1289 102 0.519
nervous system disease DOID:863 431 0.519
intrinsic cardiomyopathy DOID:0060036 50 0.329
Human
dilated cardiomyopathy DOID:12930 32 0.228
skin disease DOID:37 33 0.159
integumentary system disease DOID:16 43 0.159
bone disease DOID:0080001 88 0.125
connective tissue disease DOID:65 109 0.125
disease of metabolism DOID:0014667 295 0.104
acquired metabolic disease DOID:0060158 58 0.064
dementia DOID:1307 19 0.059
alzheimer s disease DOID:10652 16 0.059
bone development disease DOID:0080006 55 0.053
brain disease DOID:936 73 0.043
gastrointestinal system cancer DOID:3119 52 0.035
cancer DOID:162 167 0.035
disease of cellular proliferation DOID:14566 174 0.035
organ system cancer DOID:0050686 164 0.035
immune system disease DOID:2914 155 0.023