Homo sapiens

40 known processes

PLAT

plasminogen activator, tissue

(Aliases: DKFZp686I03148,T-PA,TPA)

PLAT biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
plasminogen activation GO:0031639 11 1.000
leukotriene production involved in inflammatory response GO:0002540 1 0.998
angiogenesis involved in wound healing GO:0060055 4 0.993
kinin cascade GO:0002254 1 0.986
Human
vascular wound healing GO:0061042 4 0.964
regulation of fibrinolysis GO:0051917 8 0.917
Human
regulation of keratinocyte migration GO:0051547 4 0.901
negative regulation of plasminogen activation GO:0010757 4 0.894
regulation of vascular wound healing GO:0061043 2 0.823
regulation of smooth muscle cell matrix adhesion GO:2000097 3 0.780
Human
positive regulation of keratinocyte migration GO:0051549 4 0.736
regulation of smooth muscle cell migration GO:0014910 15 0.720
Human
negative regulation of peptidase activity GO:0010466 91 0.708
Human
negative regulation of fibrinolysis GO:0051918 5 0.652
Human
regulation of locomotion GO:0040012 329 0.639
Human
negative regulation of developmental process GO:0051093 247 0.620
negative regulation of smooth muscle cell migration GO:0014912 7 0.588
positive regulation of hemostasis GO:1900048 11 0.569
Human
negative regulation of hemostasis GO:1900047 22 0.541
Human
blood coagulation GO:0007596 76 0.533
Human
astrocyte differentiation GO:0048708 4 0.524
regulation of leukocyte chemotaxis GO:0002688 46 0.515
positive regulation of blood coagulation GO:0030194 11 0.514
Human
cellular response to camp GO:0071320 21 0.506
circulatory system development GO:0072359 262 0.505
organ morphogenesis GO:0009887 147 0.499
Human
negative regulation of blood coagulation GO:0030195 22 0.498
Human
negative regulation of multicellular organismal process GO:0051241 317 0.494
Human
morphogenesis of a branching structure GO:0001763 21 0.492
Human
regulation of cell motility GO:2000145 299 0.491
Human
negative regulation of cell adhesion GO:0007162 64 0.485
Human
ion transmembrane transport GO:0034220 338 0.483
cardiovascular system development GO:0072358 262 0.483
regulation of cell migration GO:0030334 289 0.480
Human
muscle cell migration GO:0014812 19 0.466
Human Mouse
regulation of peptidase activity GO:0052547 180 0.453
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.442
positive regulation of gliogenesis GO:0014015 4 0.442
transmembrane transport GO:0055085 399 0.437
regulation of coagulation GO:0050818 44 0.433
Human
cellular response to gonadotropin stimulus GO:0071371 4 0.432
blood vessel morphogenesis GO:0048514 162 0.427
protein processing GO:0016485 226 0.426
blood vessel development GO:0001568 172 0.422
negative regulation of coagulation GO:0050819 24 0.421
Human
positive regulation of cellular component organization GO:0051130 376 0.420
regeneration GO:0031099 4 0.399
response to organonitrogen compound GO:0010243 156 0.395
Rat
biological adhesion GO:0022610 331 0.391
Human
positive regulation of calcium ion transport GO:0051928 51 0.390
cell adhesion GO:0007155 325 0.387
Human
cellular response to organic cyclic compound GO:0071407 127 0.385
Rat
positive regulation of immune system process GO:0002684 283 0.379
cellular amine metabolic process GO:0044106 41 0.378
epithelium development GO:0060429 227 0.376
Human
response to organic cyclic compound GO:0014070 204 0.375
Rat
tissue morphogenesis GO:0048729 96 0.375
Human
regulation of endopeptidase activity GO:0052548 170 0.374
Human
cellular response to oxygen containing compound GO:1901701 276 0.373
Human Rat
tissue regeneration GO:0042246 3 0.367
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling GO:0060665 1 0.367
Human
regulation of response to external stimulus GO:0032101 222 0.366
Human
positive regulation of leukocyte chemotaxis GO:0002690 38 0.365
regulation of chemotaxis GO:0050920 74 0.363
positive regulation of coagulation GO:0050820 11 0.360
Human
cellular response to endogenous stimulus GO:0071495 336 0.356
Rat
peptidyl tyrosine modification GO:0018212 170 0.355
Human
response to oxygen containing compound GO:1901700 369 0.349
Human Rat
cell substrate adhesion GO:0031589 132 0.349
Human
positive regulation of cell proliferation GO:0008284 301 0.346
negative regulation of locomotion GO:0040013 118 0.345
angiogenesis GO:0001525 147 0.344
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.344
Human Mouse
regulation of leukocyte migration GO:0002685 63 0.341
positive regulation of protein phosphorylation GO:0001934 313 0.340
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.337
negative regulation of vasculature development GO:1901343 43 0.336
response to camp GO:0051591 25 0.335
Rat
regulation of astrocyte differentiation GO:0048710 3 0.334
leukocyte activation GO:0045321 164 0.331
negative regulation of wound healing GO:0061045 25 0.322
Human
regulation of cytokine production GO:0001817 232 0.322
urogenital system development GO:0001655 65 0.321
coagulation GO:0050817 78 0.319
Human
cell chemotaxis GO:0060326 112 0.316
Human
cytokine production GO:0001816 247 0.315
hemostasis GO:0007599 76 0.315
Human
regulation of blood coagulation GO:0030193 42 0.315
Human
regulation of cell differentiation GO:0045595 393 0.314
cellular response to nitrogen compound GO:1901699 144 0.312
taxis GO:0042330 157 0.312
Human
cellular amino acid metabolic process GO:0006520 116 0.308
regulation of cellular ketone metabolic process GO:0010565 50 0.302
negative regulation of cell death GO:0060548 345 0.301
Human
regulation of epithelial cell migration GO:0010632 93 0.298
cellular response to glucocorticoid stimulus GO:0071385 4 0.292
Rat
regulation of protein maturation GO:1903317 150 0.292
regulation of body fluid levels GO:0050878 99 0.288
Human
negative regulation of response to external stimulus GO:0032102 83 0.287
Human
positive regulation of locomotion GO:0040017 186 0.287
Human
vasculature development GO:0001944 181 0.280
positive regulation of cytokine production GO:0001819 167 0.278
chemotaxis GO:0006935 157 0.277
Human
positive regulation of cell motility GO:2000147 177 0.277
Human
regulation of cellular component movement GO:0051270 334 0.275
Human
negative regulation of protein metabolic process GO:0051248 391 0.275
negative regulation of cell motility GO:2000146 104 0.272
leukocyte migration GO:0050900 107 0.271
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.270
zymogen activation GO:0031638 70 0.269
positive regulation of chemotaxis GO:0050921 57 0.267
regulation of behavior GO:0050795 82 0.265
response to hyperoxia GO:0055093 4 0.263
negative regulation of cell migration GO:0030336 102 0.262
regulation of cell substrate adhesion GO:0010810 68 0.260
Human
response to potassium ion GO:0035864 5 0.259
cell development GO:0048468 328 0.258
protein maturation GO:0051604 233 0.256
positive regulation of cellular amine metabolic process GO:0033240 7 0.254
regulation of protein processing GO:0070613 150 0.253
chemical homeostasis GO:0048878 306 0.249
cellular response to cytokine stimulus GO:0071345 181 0.247
response to growth factor GO:0070848 205 0.247
Human
negative regulation of cellular component movement GO:0051271 106 0.245
fibrinolysis GO:0042730 11 0.245
Human
positive regulation of cell differentiation GO:0045597 211 0.241
response to nitrogen compound GO:1901698 184 0.240
Rat
regulation of proteolysis GO:0030162 293 0.236
negative regulation of hydrogen peroxide mediated programmed cell death GO:1901299 3 0.231
Human
response to wounding GO:0009611 168 0.230
Human Rat
epithelial cell migration GO:0010631 119 0.224
negative regulation of proteolysis GO:0045861 132 0.219
apoptotic signaling pathway GO:0097190 268 0.218
Human
response to increased oxygen levels GO:0036296 4 0.218
negative regulation of catalytic activity GO:0043086 335 0.218
Human
factor xii activation GO:0002542 1 0.218
Human
positive regulation of transport GO:0051050 336 0.213
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.213
leukocyte chemotaxis GO:0030595 76 0.212
response to other organism GO:0051707 261 0.211
positive regulation of developmental process GO:0051094 314 0.206
cellular response to lipid GO:0071396 127 0.205
Rat
wound healing GO:0042060 115 0.204
Human Rat
positive regulation of behavior GO:0048520 60 0.203
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.201
negative regulation of response to wounding GO:1903035 47 0.200
Human
single organismal cell cell adhesion GO:0016337 148 0.200
nervous system development GO:0007399 293 0.199
response to biotic stimulus GO:0009607 276 0.192
growth GO:0040007 202 0.192
response to abiotic stimulus GO:0009628 336 0.191
Mouse
defense response GO:0006952 315 0.190
Human
positive regulation of epithelial cell migration GO:0010634 55 0.189
negative regulation of programmed cell death GO:0043069 321 0.189
Human
regulation of plasminogen activation GO:0010755 7 0.189
Human
cellular response to glucagon stimulus GO:0071377 1 0.186
programmed cell death in response to reactive oxygen species GO:0097468 4 0.186
Human
cellular response to growth factor stimulus GO:0071363 197 0.186
Human
ameboidal type cell migration GO:0001667 135 0.185
response to organophosphorus GO:0046683 41 0.184
Rat
female gamete generation GO:0007292 2 0.184
Rat
negative regulation of angiogenesis GO:0016525 39 0.180
response to external biotic stimulus GO:0043207 261 0.178
positive regulation of cell migration GO:0030335 172 0.177
Human
cell matrix adhesion GO:0007160 85 0.174
Human
cell activation GO:0001775 213 0.173
regulation of calcium ion transport GO:0051924 79 0.173
myeloid leukocyte migration GO:0097529 62 0.171
cellular response to organonitrogen compound GO:0071417 124 0.168
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.167
keratinocyte migration GO:0051546 6 0.164
response to molecule of bacterial origin GO:0002237 82 0.164
negative regulation of hydrolase activity GO:0051346 182 0.163
Human
negative regulation of apoptotic process GO:0043066 316 0.163
Human
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.162
cell type specific apoptotic process GO:0097285 125 0.159
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.158
Human
hydrogen peroxide mediated programmed cell death GO:0010421 4 0.157
Human
tissue migration GO:0090130 119 0.156
metal ion transport GO:0030001 272 0.156
negative regulation of cellular protein metabolic process GO:0032269 353 0.155
protein autoprocessing GO:0016540 4 0.154
Human
regulation of receptor mediated endocytosis GO:0048259 32 0.154
response to transforming growth factor beta GO:0071559 94 0.154
central nervous system development GO:0007417 123 0.153
positive regulation of phosphorylation GO:0042327 394 0.153
Human
cation transport GO:0006812 331 0.153
negative regulation of protein maturation GO:1903318 142 0.152
vesicle mediated transport GO:0016192 371 0.152
negative regulation of blood vessel morphogenesis GO:2000181 41 0.152
positive regulation of cellular component movement GO:0051272 181 0.151
Human
response to bacterium GO:0009617 144 0.151
negative regulation of cellular component organization GO:0051129 235 0.151
Human
response to purine containing compound GO:0014074 40 0.151
Rat
cellular response to interleukin 1 GO:0071347 35 0.150
cellular response to molecule of bacterial origin GO:0071219 62 0.149
response to glucagon GO:0033762 1 0.149
regulation of oxidative stress induced cell death GO:1903201 24 0.148
Human
regulation of cell matrix adhesion GO:0001952 42 0.147
Human
tube development GO:0035295 125 0.147
regulation of apoptotic signaling pathway GO:2001233 175 0.145
Human
extrinsic apoptotic signaling pathway GO:0097191 119 0.144
regulation of transmembrane transport GO:0034762 139 0.142
smooth muscle cell migration GO:0014909 18 0.141
Human Mouse
positive regulation of endocytosis GO:0045807 42 0.140
post embryonic development GO:0009791 2 0.138
morphogenesis of an epithelium GO:0002009 60 0.138
Human
cellular ketone metabolic process GO:0042180 80 0.137
positive regulation of interleukin 8 production GO:0032757 36 0.136
endothelial cell apoptotic process GO:0072577 26 0.135
epithelial cell proliferation GO:0050673 128 0.135
single organism cell adhesion GO:0098602 179 0.132
calcium ion transport GO:0006816 147 0.130
renal system development GO:0072001 63 0.129
response to low density lipoprotein particle GO:0055098 4 0.128
response to activity GO:0014823 0 0.127
cellular response to cgmp GO:0071321 5 0.127
positive regulation of protein processing GO:0010954 6 0.127
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.125
Human
response to mechanical stimulus GO:0009612 51 0.125
regulation of cell adhesion GO:0030155 166 0.123
Human
positive regulation of cell death GO:0010942 263 0.123
behavior GO:0007610 112 0.122
divalent metal ion transport GO:0070838 152 0.122
regulation of hemostasis GO:1900046 42 0.122
Human
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.120
Human
cellular response to corticosteroid stimulus GO:0071384 5 0.120
Rat
positive regulation of response to wounding GO:1903036 28 0.119
Human
positive regulation of leukocyte migration GO:0002687 46 0.118
cellular response to metal ion GO:0071248 43 0.118
regulation of defense response GO:0031347 154 0.117
Human
positive regulation of cell development GO:0010720 92 0.116
response to lipopolysaccharide GO:0032496 70 0.116
cellular response to oxidative stress GO:0034599 85 0.116
Human
amine metabolic process GO:0009308 44 0.114
regulation of cell development GO:0060284 161 0.112
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.111
Human
positive regulation of hydrolase activity GO:0051345 331 0.111
regulation of glial cell differentiation GO:0045685 3 0.111
response to inorganic substance GO:0010035 127 0.110
Human
regulation of endothelial cell apoptotic process GO:2000351 24 0.109
regulation of ion transport GO:0043269 189 0.108
positive regulation of programmed cell death GO:0043068 249 0.108
cellular homeostasis GO:0019725 196 0.107
inflammatory response GO:0006954 79 0.107
Human
regulation of inflammatory response GO:0050727 46 0.107
Human
calcium ion import GO:0070509 23 0.106
response to hormone GO:0009725 175 0.106
Rat
regulation of cysteine type endopeptidase activity GO:2000116 127 0.104
Human
monocyte chemotaxis GO:0002548 20 0.104
regulation of wound healing GO:0061041 56 0.104
Human
protein activation cascade GO:0072376 22 0.102
Human
negative regulation of apoptotic signaling pathway GO:2001234 97 0.101
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.100
Human Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.100
regulation of transferase activity GO:0051338 355 0.100
cellular response to dexamethasone stimulus GO:0071549 1 0.099
Rat
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.098
Human
cellular response to lipopolysaccharide GO:0071222 57 0.096
regulation of vesicle mediated transport GO:0060627 130 0.096
negative regulation of cell substrate adhesion GO:0010812 24 0.096
Human
regulation of multi organism process GO:0043900 157 0.096
Rat
regulation of response to wounding GO:1903034 101 0.095
Human
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.095
regulation of ion transmembrane transport GO:0034765 132 0.095
regulation of cell adhesion mediated by integrin GO:0033628 22 0.093
Human
cellular response to hypoxia GO:0071456 51 0.093
positive regulation of transferase activity GO:0051347 227 0.091
cell death in response to oxidative stress GO:0036473 29 0.090
Human
cellular chemical homeostasis GO:0055082 180 0.090
epithelium migration GO:0090132 119 0.089
response to lipid GO:0033993 206 0.088
Rat
negative regulation of oxidative stress induced cell death GO:1903202 17 0.087
Human
cellular response to biotic stimulus GO:0071216 71 0.087
regulation of epithelial cell proliferation GO:0050678 113 0.087
generation of neurons GO:0048699 152 0.086
reactive oxygen species metabolic process GO:0072593 75 0.086
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.085
response to cytokine GO:0034097 232 0.085
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.085
cellular response to decreased oxygen levels GO:0036294 51 0.083
cell morphogenesis involved in differentiation GO:0000904 144 0.083
positive regulation of angiogenesis GO:0045766 51 0.082
cellular response to mechanical stimulus GO:0071260 39 0.082
response to peptide hormone GO:0043434 61 0.081
Rat
regulation of protein localization GO:0032880 296 0.081
cellular response to steroid hormone stimulus GO:0071383 37 0.081
Rat
regulation of vasculature development GO:1901342 97 0.080
endocytosis GO:0006897 159 0.080
system process GO:0003008 349 0.079
regulation of reactive oxygen species metabolic process GO:2000377 41 0.079
regulation of cellular response to stress GO:0080135 244 0.079
Human
epithelial cell differentiation GO:0030855 141 0.079
retina vasculature development in camera type eye GO:0061298 3 0.079
cellular response to reactive oxygen species GO:0034614 50 0.078
Human
cellular response to peptide GO:1901653 59 0.078
basement membrane organization GO:0071711 3 0.076
regulation of protein transport GO:0051223 213 0.074
positive regulation of fibroblast proliferation GO:0048146 21 0.074
cellular response to low density lipoprotein particle stimulus GO:0071404 1 0.072
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.070
tube morphogenesis GO:0035239 95 0.070
cellular response to abiotic stimulus GO:0071214 117 0.070
positive regulation of wound healing GO:0090303 20 0.070
Human
hepatocyte growth factor receptor signaling pathway GO:0048012 8 0.069
Human
response to hydrogen peroxide GO:0042542 40 0.069
Human
cellular response to hydrogen peroxide GO:0070301 37 0.069
Human
negative regulation of protein processing GO:0010955 142 0.068
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.068
neurogenesis GO:0022008 169 0.068
cellular response to alkaloid GO:0071312 11 0.067
regulation of metal ion transport GO:0010959 120 0.067
positive regulation of monocyte chemotaxis GO:0090026 10 0.067
regulation of cellular response to oxidative stress GO:1900407 26 0.067
Human
secretion by cell GO:0032940 226 0.066
cellular response to oxygen levels GO:0071453 55 0.066
regulation of kinase activity GO:0043549 314 0.065
negative regulation of endothelial cell apoptotic process GO:2000352 16 0.065
positive chemotaxis GO:0050918 33 0.065
Human
embryonic morphogenesis GO:0048598 85 0.064
response to hypoxia GO:0001666 96 0.064
Mouse
endothelial cell migration GO:0043542 86 0.063
regulation of monocyte chemotaxis GO:0090025 11 0.063
neuromuscular junction development GO:0007528 3 0.063
regulation of growth GO:0040008 165 0.062
positive regulation of protein kinase activity GO:0045860 190 0.062
gland development GO:0048732 48 0.062
Human
regulation of establishment of protein localization GO:0070201 242 0.061
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.060
Human
negative regulation of cell proliferation GO:0008285 228 0.060
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.060
endodermal cell differentiation GO:0035987 31 0.060
digestive tract development GO:0048565 75 0.060
response to steroid hormone GO:0048545 80 0.059
Rat
actin filament based process GO:0030029 224 0.059
positive regulation of kinase activity GO:0033674 204 0.058
regulation of endocytosis GO:0030100 72 0.057
regulation of angiogenesis GO:0045765 92 0.057
chronological cell aging GO:0001300 2 0.057
cell morphogenesis GO:0000902 296 0.056
cell growth GO:0016049 160 0.056
cell aging GO:0007569 52 0.056
positive regulation of response to external stimulus GO:0032103 88 0.055
Human
cellular response to peptide hormone stimulus GO:0071375 56 0.055
divalent inorganic cation transport GO:0072511 158 0.055
cell projection organization GO:0030030 252 0.055
release of cytochrome c from mitochondria GO:0001836 35 0.055
Human
extracellular matrix organization GO:0030198 41 0.054
Human
response to fibroblast growth factor GO:0071774 39 0.054
response to drug GO:0042493 81 0.053
morphogenesis of a polarized epithelium GO:0001738 3 0.053
regulation of receptor activity GO:0010469 47 0.052
Human
cellular response to lipoprotein particle stimulus GO:0071402 1 0.052
cellular response to alcohol GO:0097306 29 0.052
Rat
reproductive process GO:0022414 106 0.052
Rat
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.051
Human
positive regulation of ion transport GO:0043270 87 0.051
response to oxidative stress GO:0006979 121 0.051
Human
response to estrogen GO:0043627 47 0.050
peptidyl tyrosine phosphorylation GO:0018108 170 0.050
Human
cellular response to potassium ion GO:0035865 5 0.050
osteoblast differentiation GO:0001649 92 0.049
regulation of protein serine threonine kinase activity GO:0071900 179 0.049
immune response GO:0006955 307 0.049
single organism cellular localization GO:1902580 332 0.048
mapk cascade GO:0000165 288 0.048
cellular response to ammonium ion GO:0071242 4 0.048
apoptotic mitochondrial changes GO:0008637 57 0.048
Human
response to alcohol GO:0097305 64 0.048
Rat
regulation of leukocyte activation GO:0002694 115 0.047
purine nucleotide catabolic process GO:0006195 405 0.047
morphogenesis of a branching epithelium GO:0061138 20 0.047
Human
nucleoside phosphate catabolic process GO:1901292 412 0.046
regulation of cellular component biogenesis GO:0044087 281 0.046
signal transduction by phosphorylation GO:0023014 297 0.045
regulation of protein kinase activity GO:0045859 289 0.045
organic hydroxy compound metabolic process GO:1901615 147 0.045
endoderm development GO:0007492 33 0.044
regulation of nervous system development GO:0051960 88 0.044
myeloid leukocyte activation GO:0002274 34 0.044
single organism carbohydrate metabolic process GO:0044723 193 0.044
regulation of dna metabolic process GO:0051052 153 0.043
Human
cell adhesion mediated by integrin GO:0033627 27 0.043
Human
secretion GO:0046903 254 0.043
glucose homeostasis GO:0042593 31 0.043
regulation of fibroblast proliferation GO:0048145 32 0.043
oogenesis GO:0048477 2 0.043
positive regulation of proteolysis GO:0045862 142 0.042
response to reactive oxygen species GO:0000302 61 0.042
Human
inner ear morphogenesis GO:0042472 4 0.042
cellular response to external stimulus GO:0071496 111 0.042
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.042
smooth muscle cell matrix adhesion GO:0061302 5 0.042
Human
membrane organization GO:0061024 292 0.042
small gtpase mediated signal transduction GO:0007264 78 0.041
positive regulation of nervous system development GO:0051962 54 0.041
protein catabolic process GO:0030163 325 0.041
muscle structure development GO:0061061 98 0.041
cellular response to nerve growth factor stimulus GO:1990090 6 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.040
regulation of cell projection organization GO:0031344 107 0.040
cellular response to monosaccharide stimulus GO:0071326 10 0.040
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.040
Human
carbohydrate metabolic process GO:0005975 207 0.040
negative regulation of phosphate metabolic process GO:0045936 267 0.040
morphogenesis of embryonic epithelium GO:0016331 4 0.040
response to fluid shear stress GO:0034405 14 0.039
glycosyl compound catabolic process GO:1901658 413 0.039
cellular response to hepatocyte growth factor stimulus GO:0035729 6 0.039
Human
response to oxygen levels GO:0070482 100 0.039
Mouse
segmentation GO:0035282 4 0.038
phosphatidylinositol mediated signaling GO:0048015 55 0.038
Human
activation of protein kinase activity GO:0032147 90 0.038
purine ribonucleoside catabolic process GO:0046130 398 0.038
digestive tract morphogenesis GO:0048546 56 0.038
cytoplasmic transport GO:0016482 379 0.038
response to decreased oxygen levels GO:0036293 96 0.038
Mouse
regulation of cell activation GO:0050865 125 0.037
negative regulation of cell differentiation GO:0045596 171 0.037
regulation of secretion by cell GO:1903530 177 0.037
single organism reproductive process GO:0044702 98 0.037
Rat
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.037
brain development GO:0007420 97 0.036
multicellular organismal aging GO:0010259 3 0.036
developmental growth GO:0048589 48 0.036
organophosphate catabolic process GO:0046434 430 0.036
cellular glucose homeostasis GO:0001678 11 0.036
actin cytoskeleton organization GO:0030036 207 0.036
response to nutrient levels GO:0031667 81 0.035
cellular lipid metabolic process GO:0044255 303 0.035
small molecule biosynthetic process GO:0044283 157 0.035
endothelial cell proliferation GO:0001935 65 0.035
regulation of smooth muscle cell proliferation GO:0048660 28 0.035
defense response to other organism GO:0098542 129 0.035
regulation of branching involved in salivary gland morphogenesis GO:0060693 1 0.035
Human
formation of primary germ layer GO:0001704 42 0.034
cyclic nucleotide metabolic process GO:0009187 82 0.034
embryo development GO:0009790 123 0.034
reproductive structure development GO:0048608 55 0.034
response to misfolded protein GO:0051788 5 0.034
Human
regulation of cellular response to growth factor stimulus GO:0090287 76 0.034
decidualization GO:0046697 4 0.034
positive regulation of organelle organization GO:0010638 195 0.034
positive regulation of map kinase activity GO:0043406 80 0.034
nucleoside catabolic process GO:0009164 408 0.034
negative regulation of transport GO:0051051 176 0.033
dna biosynthetic process GO:0071897 40 0.033
Human
mesenchymal epithelial cell signaling GO:0060638 1 0.033
Human
cellular response to inorganic substance GO:0071241 45 0.033
response to epidermal growth factor GO:0070849 14 0.033
negative regulation of phosphorus metabolic process GO:0010563 267 0.033
developmental process involved in reproduction GO:0003006 66 0.033
response to ketone GO:1901654 19 0.033
Rat
purine ribonucleoside metabolic process GO:0046128 437 0.032
receptor mediated endocytosis GO:0006898 84 0.032
cellular component morphogenesis GO:0032989 314 0.032
muscle system process GO:0003012 81 0.032
carbohydrate homeostasis GO:0033500 31 0.032
nucleotide catabolic process GO:0009166 408 0.032
purine ribonucleotide catabolic process GO:0009154 404 0.032
nucleoside triphosphate catabolic process GO:0009143 394 0.032
interleukin 8 production GO:0032637 51 0.032
purine nucleoside triphosphate catabolic process GO:0009146 392 0.032
ras protein signal transduction GO:0007265 73 0.031
response to monosaccharide GO:0034284 20 0.031
response to corticosteroid GO:0031960 15 0.031
Rat
positive regulation of calcium ion import GO:0090280 6 0.031
positive regulation of smooth muscle cell migration GO:0014911 6 0.031
response to nicotine GO:0035094 12 0.031
positive regulation of defense response GO:0031349 87 0.031
Human
determination of adult lifespan GO:0008340 2 0.031
inositol lipid mediated signaling GO:0048017 55 0.031
Human
positive regulation of neurogenesis GO:0050769 49 0.031
ribonucleotide catabolic process GO:0009261 405 0.031
glomerular basement membrane development GO:0032836 3 0.030
cellular response to insulin stimulus GO:0032869 41 0.030
negative regulation of cell matrix adhesion GO:0001953 14 0.030
positive regulation of intracellular transport GO:0032388 104 0.030
positive regulation of inflammatory response GO:0050729 10 0.030
Human
branching morphogenesis of an epithelial tube GO:0048754 19 0.030
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.030
patterning of blood vessels GO:0001569 2 0.029
purine containing compound catabolic process GO:0072523 411 0.029
endomembrane system organization GO:0010256 196 0.028
regulation of protein secretion GO:0050708 86 0.028
positive regulation of epithelial cell proliferation GO:0050679 65 0.027
defense response to bacterium GO:0042742 63 0.027
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.027
response to insulin GO:0032868 45 0.027

PLAT disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.113
Human
nervous system disease DOID:863 431 0.113
Human
neurodegenerative disease DOID:1289 102 0.102
Human
tauopathy DOID:680 16 0.045
Human
cardiovascular system disease DOID:1287 106 0.034