Homo sapiens

54 known processes

PLAU

plasminogen activator, urokinase

(Aliases: ATF,u-PA,URK,UPA)

PLAU biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
leukotriene production involved in inflammatory response GO:0002540 1 1.000
plasminogen activation GO:0031639 11 1.000
Human
angiogenesis involved in wound healing GO:0060055 4 1.000
regulation of plasminogen activation GO:0010755 7 1.000
Human
positive regulation of blood coagulation GO:0030194 11 1.000
Human
vascular wound healing GO:0061042 4 1.000
negative regulation of plasminogen activation GO:0010757 4 1.000
regulation of fibrinolysis GO:0051917 8 0.998
Human
regulation of vascular wound healing GO:0061043 2 0.995
positive regulation of keratinocyte migration GO:0051549 4 0.992
smooth muscle cell matrix adhesion GO:0061302 5 0.987
regulation of smooth muscle cell matrix adhesion GO:2000097 3 0.983
regulation of keratinocyte migration GO:0051547 4 0.981
positive regulation of hemostasis GO:1900048 11 0.971
Human
kinin cascade GO:0002254 1 0.969
Human
regulation of astrocyte differentiation GO:0048710 3 0.961
muscle cell migration GO:0014812 19 0.960
cellular amine metabolic process GO:0044106 41 0.958
response to low density lipoprotein particle GO:0055098 4 0.951
negative regulation of wound healing GO:0061045 25 0.919
Human Mouse
response to glucagon GO:0033762 1 0.916
regulation of cellular ketone metabolic process GO:0010565 50 0.910
cellular response to molecule of bacterial origin GO:0071219 62 0.908
Rat
negative regulation of fibrinolysis GO:0051918 5 0.900
Human
negative regulation of hemostasis GO:1900047 22 0.889
Human Mouse
regulation of leukocyte migration GO:0002685 63 0.889
regulation of chemotaxis GO:0050920 74 0.885
positive regulation of chemotaxis GO:0050921 57 0.882
positive regulation of defense response GO:0031349 87 0.880
Human
negative regulation of blood coagulation GO:0030195 22 0.869
Human Mouse
cellular response to biotic stimulus GO:0071216 71 0.864
Rat
regulation of cell migration GO:0030334 289 0.863
positive regulation of locomotion GO:0040017 186 0.854
Human Rat
biological adhesion GO:0022610 331 0.844
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.806
Human
positive regulation of cell proliferation GO:0008284 301 0.793
Rat
regulation of cellular component movement GO:0051270 334 0.785
positive regulation of gliogenesis GO:0014015 4 0.776
cellular response to glucagon stimulus GO:0071377 1 0.774
regulation of monocyte chemotaxis GO:0090025 11 0.774
divalent inorganic cation transport GO:0072511 158 0.764
positive regulation of cellular amine metabolic process GO:0033240 7 0.761
regulation of smooth muscle cell migration GO:0014910 15 0.760
regulation of glial cell differentiation GO:0045685 3 0.759
monocyte chemotaxis GO:0002548 20 0.756
cell chemotaxis GO:0060326 112 0.745
Human
regulation of blood coagulation GO:0030193 42 0.745
Human Mouse
positive regulation of response to external stimulus GO:0032103 88 0.735
Human
positive regulation of protein phosphorylation GO:0001934 313 0.729
Human
positive regulation of cell migration GO:0030335 172 0.728
Human Rat
myeloid leukocyte migration GO:0097529 62 0.727
positive regulation of cellular component movement GO:0051272 181 0.705
Human Rat
positive regulation of monocyte chemotaxis GO:0090026 10 0.692
regulation of cellular amino acid metabolic process GO:0006521 6 0.686
cell adhesion mediated by integrin GO:0033627 27 0.685
chemotaxis GO:0006935 157 0.683
Human
response to organonitrogen compound GO:0010243 156 0.681
Rat
vasculature development GO:0001944 181 0.676
Rat
response to lipopolysaccharide GO:0032496 70 0.672
Rat
negative regulation of locomotion GO:0040013 118 0.672
regulation of response to wounding GO:1903034 101 0.669
Human Mouse
response to bacterium GO:0009617 144 0.666
Rat
regulation of cell matrix adhesion GO:0001952 42 0.660
cellular response to endogenous stimulus GO:0071495 336 0.651
Rat
regulation of angiogenesis GO:0045765 92 0.646
response to fibroblast growth factor GO:0071774 39 0.645
positive regulation of coagulation GO:0050820 11 0.644
Human
fibrinolysis GO:0042730 11 0.643
Human Mouse
protein maturation GO:0051604 233 0.640
Human
regulation of ion transport GO:0043269 189 0.639
peptidyl tyrosine modification GO:0018212 170 0.638
Human
cytokine production GO:0001816 247 0.638
positive regulation of phosphorylation GO:0042327 394 0.633
Human
zymogen activation GO:0031638 70 0.627
Human
response to hyperoxia GO:0055093 4 0.623
Rat
regulation of peptidase activity GO:0052547 180 0.621
Human
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.619
cellular response to gonadotropin stimulus GO:0071371 4 0.614
taxis GO:0042330 157 0.612
Human
fibroblast proliferation GO:0048144 33 0.601
cellular response to interleukin 1 GO:0071347 35 0.591
negative regulation of smooth muscle cell migration GO:0014912 7 0.583
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.582
regulation of protein processing GO:0070613 150 0.558
Human
tissue regeneration GO:0042246 3 0.557
Rat
cellular response to lipopolysaccharide GO:0071222 57 0.550
Rat
positive regulation of ion transport GO:0043270 87 0.543
positive regulation of cytokine production GO:0001819 167 0.542
cellular response to hydrogen peroxide GO:0070301 37 0.539
Human
negative regulation of protein maturation GO:1903318 142 0.534
Human
blood coagulation GO:0007596 76 0.531
Human Mouse
negative regulation of vasculature development GO:1901343 43 0.530
negative regulation of peptidase activity GO:0010466 91 0.515
Human
regulation of coagulation GO:0050818 44 0.511
Human Mouse
negative regulation of cellular component movement GO:0051271 106 0.508
positive regulation of cell motility GO:2000147 177 0.505
Human Rat
extrinsic apoptotic signaling pathway GO:0097191 119 0.499
negative regulation of coagulation GO:0050819 24 0.498
Human Mouse
salivary gland morphogenesis GO:0007435 4 0.497
Human
response to molecule of bacterial origin GO:0002237 82 0.496
Rat
regulation of proteolysis GO:0030162 293 0.495
Human
coagulation GO:0050817 78 0.492
Human Mouse
response to interleukin 1 GO:0070555 47 0.490
regulation of calcium ion transport GO:0051924 79 0.490
decidualization GO:0046697 4 0.488
regulation of vasculature development GO:1901342 97 0.488
cellular response to camp GO:0071320 21 0.488
epithelium migration GO:0090132 119 0.485
negative regulation of apoptotic signaling pathway GO:2001234 97 0.478
Human
regulation of cell motility GO:2000145 299 0.469
response to increased oxygen levels GO:0036296 4 0.469
Rat
negative regulation of apoptotic process GO:0043066 316 0.469
Human
response to wounding GO:0009611 168 0.468
Human Mouse Rat
female gamete generation GO:0007292 2 0.464
Rat
defense response GO:0006952 315 0.461
Human
response to hydrogen peroxide GO:0042542 40 0.461
Human
response to lipid GO:0033993 206 0.458
Rat
defense response to other organism GO:0098542 129 0.457
regulation of cell adhesion mediated by integrin GO:0033628 22 0.453
response to hormone GO:0009725 175 0.453
regulation of defense response GO:0031347 154 0.451
Human
response to abiotic stimulus GO:0009628 336 0.449
Mouse Rat
positive regulation of developmental process GO:0051094 314 0.446
regulation of wound healing GO:0061041 56 0.443
Human Mouse
protein processing GO:0016485 226 0.442
Human
cell substrate adhesion GO:0031589 132 0.439
cellular response to glucocorticoid stimulus GO:0071385 4 0.438
response to decreased oxygen levels GO:0036293 96 0.431
Mouse Rat
regulation of cell adhesion GO:0030155 166 0.430
keratinocyte migration GO:0051546 6 0.430
leukocyte migration GO:0050900 107 0.428
positive regulation of leukocyte chemotaxis GO:0002690 38 0.427
positive regulation of epithelial cell migration GO:0010634 55 0.422
positive regulation of angiogenesis GO:0045766 51 0.422
cellular response to decreased oxygen levels GO:0036294 51 0.421
Rat
negative regulation of cell substrate adhesion GO:0010812 24 0.421
Human
hemostasis GO:0007599 76 0.418
Human Mouse
positive regulation of behavior GO:0048520 60 0.418
vesicle mediated transport GO:0016192 371 0.416
regulation of ion transmembrane transport GO:0034765 132 0.412
response to hexose GO:0009746 20 0.411
Rat
response to cytokine GO:0034097 232 0.410
blood vessel morphogenesis GO:0048514 162 0.409
Rat
regulation of interleukin 8 production GO:0032677 49 0.409
regulation of body fluid levels GO:0050878 99 0.407
Human Mouse
chemical homeostasis GO:0048878 306 0.404
Rat
regulation of inflammatory response GO:0050727 46 0.402
Human
cellular response to organonitrogen compound GO:0071417 124 0.401
Rat
negative regulation of response to external stimulus GO:0032102 83 0.393
Human Mouse
positive regulation of cell development GO:0010720 92 0.390
regulation of hemostasis GO:1900046 42 0.388
Human Mouse
negative regulation of hydrolase activity GO:0051346 182 0.387
Human
ion transmembrane transport GO:0034220 338 0.385
regulation of response to external stimulus GO:0032101 222 0.383
Human Mouse
response to nerve growth factor GO:1990089 6 0.381
cellular response to glucose stimulus GO:0071333 10 0.375
Rat
interleukin 8 production GO:0032637 51 0.375
factor xii activation GO:0002542 1 0.373
Human
response to cycloheximide GO:0046898 1 0.372
positive regulation of interleukin 8 production GO:0032757 36 0.370
blood vessel development GO:0001568 172 0.366
Rat
regulation of receptor mediated endocytosis GO:0048259 32 0.364
negative regulation of response to wounding GO:1903035 47 0.354
Human Mouse
cellular response to lipoprotein particle stimulus GO:0071402 1 0.341
response to biotic stimulus GO:0009607 276 0.337
Rat
positive regulation of fibroblast proliferation GO:0048146 21 0.327
negative regulation of cell migration GO:0030336 102 0.323
cellular response to dexamethasone stimulus GO:0071549 1 0.320
tissue migration GO:0090130 119 0.319
calcium ion import GO:0070509 23 0.316
response to purine containing compound GO:0014074 40 0.315
regulation of leukocyte chemotaxis GO:0002688 46 0.315
positive regulation of immune system process GO:0002684 283 0.309
cellular response to abiotic stimulus GO:0071214 117 0.307
cellular response to oxygen containing compound GO:1901701 276 0.301
Human Rat
extracellular matrix organization GO:0030198 41 0.299
Human
organ morphogenesis GO:0009887 147 0.298
Human Rat
regulation of anatomical structure morphogenesis GO:0022603 286 0.297
Human Rat
regulation of cellular amine metabolic process GO:0033238 11 0.294
positive regulation of calcium ion transport GO:0051928 51 0.292
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.291
cellular response to nerve growth factor stimulus GO:1990090 6 0.289
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.289
negative regulation of programmed cell death GO:0043069 321 0.286
Human
positive regulation of ion transmembrane transport GO:0034767 40 0.284
cellular response to nitrogen compound GO:1901699 144 0.283
Rat
cellular response to mechanical stimulus GO:0071260 39 0.283
single organismal cell cell adhesion GO:0016337 148 0.281
cellular response to peptide hormone stimulus GO:0071375 56 0.280
inflammatory response GO:0006954 79 0.277
Human
cell activation GO:0001775 213 0.275
maternal placenta development GO:0001893 5 0.270
regulation of calcium ion import GO:0090279 11 0.270
regulation of cell cell adhesion GO:0022407 57 0.269
endoderm formation GO:0001706 33 0.268
negative regulation of multicellular organismal process GO:0051241 317 0.264
Human Mouse
response to organic cyclic compound GO:0014070 204 0.263
Rat
mapk cascade GO:0000165 288 0.262
regulation of transmembrane transport GO:0034762 139 0.259
regulation of establishment of protein localization GO:0070201 242 0.249
cellular response to oxidative stress GO:0034599 85 0.245
Human
cell adhesion GO:0007155 325 0.243
positive regulation of wound healing GO:0090303 20 0.242
Human
single organism cell adhesion GO:0098602 179 0.242
tube development GO:0035295 125 0.240
response to steroid hormone GO:0048545 80 0.231
response to oxygen containing compound GO:1901700 369 0.231
Human Rat
positive regulation of leukocyte migration GO:0002687 46 0.227
cellular response to hepatocyte growth factor stimulus GO:0035729 6 0.227
Human Rat
cellular response to reactive oxygen species GO:0034614 50 0.226
Human
cellular response to lipid GO:0071396 127 0.224
Rat
response to oxidative stress GO:0006979 121 0.224
Human
positive regulation of glial cell differentiation GO:0045687 2 0.224
cellular response to cgmp GO:0071321 5 0.223
neuron projection regeneration GO:0031102 1 0.221
negative regulation of blood vessel morphogenesis GO:2000181 41 0.218
positive regulation of neurogenesis GO:0050769 49 0.215
cellular glucose homeostasis GO:0001678 11 0.215
Rat
regulation of locomotion GO:0040012 329 0.214
regulation of cytokine production GO:0001817 232 0.213
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.212
Human
response to carbohydrate GO:0009743 21 0.211
Rat
positive regulation of macrophage chemotaxis GO:0010759 3 0.211
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.208
generation of neurons GO:0048699 152 0.207
endothelial cell apoptotic process GO:0072577 26 0.204
chronological cell aging GO:0001300 2 0.203
response to oxygen levels GO:0070482 100 0.201
Mouse Rat
negative regulation of hydrogen peroxide mediated programmed cell death GO:1901299 3 0.200
Human
positive regulation of nervous system development GO:0051962 54 0.199
response to reactive oxygen species GO:0000302 61 0.198
Human
regulation of cell projection organization GO:0031344 107 0.196
negative regulation of cellular protein metabolic process GO:0032269 353 0.195
Human
hydrogen peroxide mediated programmed cell death GO:0010421 4 0.194
Human
regulation of behavior GO:0050795 82 0.193
response to starvation GO:0042594 59 0.192
cyclic nucleotide metabolic process GO:0009187 82 0.192
regulation of receptor activity GO:0010469 47 0.191
negative regulation of cell death GO:0060548 345 0.190
Human
positive regulation of transmembrane transport GO:0034764 41 0.189
positive regulation of response to wounding GO:1903036 28 0.188
Human
angiogenesis GO:0001525 147 0.187
Rat
cellular amino acid metabolic process GO:0006520 116 0.187
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.186
Human
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.183
Human
response to fluid shear stress GO:0034405 14 0.183
Rat
regulation of endothelial cell apoptotic process GO:2000351 24 0.180
smooth muscle cell migration GO:0014909 18 0.175
cellular response to low density lipoprotein particle stimulus GO:0071404 1 0.169
positive regulation of cellular component organization GO:0051130 376 0.169
response to camp GO:0051591 25 0.165
regulation of protein localization GO:0032880 296 0.165
nervous system development GO:0007399 293 0.164
negative regulation of catalytic activity GO:0043086 335 0.163
Human
regulation of metal ion transport GO:0010959 120 0.162
regulation of synaptic plasticity GO:0048167 3 0.161
negative regulation of cell adhesion GO:0007162 64 0.158
Human
negative regulation of cell motility GO:2000146 104 0.158
regulation of apoptotic signaling pathway GO:2001233 175 0.158
Human
negative regulation of protein processing GO:0010955 142 0.158
Human
female pregnancy GO:0007565 17 0.157
Rat
cell matrix adhesion GO:0007160 85 0.155
regulation of erk1 and erk2 cascade GO:0070372 99 0.155
cell development GO:0048468 328 0.154
cell projection organization GO:0030030 252 0.151
cellular response to corticosteroid stimulus GO:0071384 5 0.151
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.151
response to ketone GO:1901654 19 0.151
myeloid leukocyte activation GO:0002274 34 0.150
anatomical structure formation involved in morphogenesis GO:0048646 284 0.150
Rat
regulation of cell development GO:0060284 161 0.143
leukocyte chemotaxis GO:0030595 76 0.143
cell morphogenesis GO:0000902 296 0.143
negative regulation of developmental process GO:0051093 247 0.142
apoptotic signaling pathway GO:0097190 268 0.142
Human
programmed cell death in response to reactive oxygen species GO:0097468 4 0.141
Human
cellular response to alkaloid GO:0071312 11 0.140
Rat
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.140
regulation of vesicle mediated transport GO:0060627 130 0.140
embryonic morphogenesis GO:0048598 85 0.139
cellular response to oxygen levels GO:0071453 55 0.138
Rat
positive regulation of cell differentiation GO:0045597 211 0.138
cellular response to hormone stimulus GO:0032870 125 0.134
response to monosaccharide GO:0034284 20 0.134
Rat
response to glucocorticoid GO:0051384 13 0.134
cellular response to alcohol GO:0097306 29 0.130
circulatory system development GO:0072359 262 0.130
Rat
mast cell activation GO:0045576 6 0.129
regulation of cysteine type endopeptidase activity GO:2000116 127 0.129
Human
digestive tract development GO:0048565 75 0.129
behavior GO:0007610 112 0.128
neurogenesis GO:0022008 169 0.127
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling GO:0060665 1 0.126
Human
regulation of cell differentiation GO:0045595 393 0.122
response to alcohol GO:0097305 64 0.121
regulation of protein maturation GO:1903317 150 0.120
Human
central nervous system development GO:0007417 123 0.117
female gonad development GO:0008585 10 0.117
cellular response to metal ion GO:0071248 43 0.116
regulation of oxidative stress induced cell death GO:1903201 24 0.115
Human
negative regulation of cell matrix adhesion GO:0001953 14 0.114
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.114
Human
regulation of nervous system development GO:0051960 88 0.113
leukocyte activation GO:0045321 164 0.113
protein autoprocessing GO:0016540 4 0.112
Human
response to organophosphorus GO:0046683 41 0.111
neuron development GO:0048666 113 0.110
regulation of lymphocyte migration GO:2000401 22 0.109
response to peptide GO:1901652 65 0.108
epithelial cell migration GO:0010631 119 0.107
purine nucleoside triphosphate metabolic process GO:0009144 412 0.106
cell aging GO:0007569 52 0.105
response to other organism GO:0051707 261 0.102
Rat
response to nicotine GO:0035094 12 0.102
tissue morphogenesis GO:0048729 96 0.102
Human
cell morphogenesis involved in differentiation GO:0000904 144 0.100
response to corticosteroid GO:0031960 15 0.099
cellular response to steroid hormone stimulus GO:0071383 37 0.098
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.098
regulation of nucleotide metabolic process GO:0006140 269 0.097
inositol lipid mediated signaling GO:0048017 55 0.097
Human
response to transforming growth factor beta GO:0071559 94 0.095
cellular response to growth factor stimulus GO:0071363 197 0.095
Human Rat
regulation of protein import into nucleus GO:0042306 78 0.094
glial cell differentiation GO:0010001 11 0.094
regulation of cell substrate adhesion GO:0010810 68 0.093
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.090
cellular response to inorganic substance GO:0071241 45 0.089
viral life cycle GO:0019058 132 0.089
positive regulation of transport GO:0051050 336 0.089
positive regulation of nucleotide metabolic process GO:0045981 230 0.089
regulation of neurogenesis GO:0050767 82 0.087
wound healing GO:0042060 115 0.087
Human Mouse Rat
positive regulation of inflammatory response GO:0050729 10 0.086
Human
single organism reproductive process GO:0044702 98 0.085
Rat
gland development GO:0048732 48 0.084
Human Rat
response to atp GO:0033198 10 0.084
response to dexamethasone GO:0071548 1 0.084
small gtpase mediated signal transduction GO:0007264 78 0.082
ribonucleotide catabolic process GO:0009261 405 0.082
positive regulation of transferase activity GO:0051347 227 0.082
follicle stimulating hormone secretion GO:0046884 3 0.082
transmembrane transport GO:0055085 399 0.080
morphogenesis of an epithelium GO:0002009 60 0.079
Human
cellular response to hexose stimulus GO:0071331 10 0.079
Rat
cellular response to ketone GO:1901655 9 0.079
cell cell signaling GO:0007267 155 0.078
Human
post embryonic development GO:0009791 2 0.078
endocytosis GO:0006897 159 0.075
protein catabolic process GO:0030163 325 0.075
nerve development GO:0021675 4 0.074
monocyte aggregation GO:0070487 4 0.074
regulation of reactive oxygen species metabolic process GO:2000377 41 0.073
Rat
negative regulation of angiogenesis GO:0016525 39 0.073
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.072
regulation of neuron differentiation GO:0045664 70 0.072
multicellular organismal metabolic process GO:0044236 34 0.071
positive regulation of dna metabolic process GO:0051054 73 0.071
Human
regulation of transferase activity GO:0051338 355 0.070
response to extracellular stimulus GO:0009991 85 0.068
positive regulation of endocytosis GO:0045807 42 0.068
positive chemotaxis GO:0050918 33 0.068
Human
cellular response to peptide GO:1901653 59 0.067
response to growth factor GO:0070848 205 0.067
Human Rat
response to metal ion GO:0010038 84 0.066
response to nitrogen compound GO:1901698 184 0.064
Rat
formation of primary germ layer GO:0001704 42 0.063
response to drug GO:0042493 81 0.063
cardiovascular system development GO:0072358 262 0.062
Rat
peptidyl tyrosine phosphorylation GO:0018108 170 0.061
Human
platelet derived growth factor receptor signaling pathway GO:0048008 14 0.061
regulation of endopeptidase activity GO:0052548 170 0.060
Human
receptor mediated endocytosis GO:0006898 84 0.059
intracellular protein transport GO:0006886 270 0.059
cation transport GO:0006812 331 0.059
regulation of dna metabolic process GO:0051052 153 0.058
Human
regulation of neurotransmitter secretion GO:0046928 3 0.058
positive regulation of secretion GO:0051047 116 0.058
negative regulation of cellular component organization GO:0051129 235 0.057
Human
dna biosynthetic process GO:0071897 40 0.057
Human
regulation of endocytosis GO:0030100 72 0.056
cell growth GO:0016049 160 0.056
response to cgmp GO:0070305 5 0.056
chronic inflammatory response GO:0002544 2 0.055
basement membrane organization GO:0071711 3 0.055
regeneration GO:0031099 4 0.055
Rat
axon regeneration GO:0031103 1 0.055
positive regulation of calcium ion import GO:0090280 6 0.055
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.054
regulation of epithelial cell migration GO:0010632 93 0.053
response to hypoxia GO:0001666 96 0.053
Mouse Rat
g protein coupled receptor signaling pathway GO:0007186 207 0.053
establishment of protein localization to organelle GO:0072594 172 0.052
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.052
Human
positive regulation of multi organism process GO:0043902 56 0.050
Rat
growth GO:0040007 202 0.050
Rat
viral process GO:0016032 146 0.050
cell death in response to oxidative stress GO:0036473 29 0.050
Human
cellular response to carbohydrate stimulus GO:0071322 11 0.049
Rat
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.049
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.049
positive regulation of nucleotide catabolic process GO:0030813 185 0.048
female sex differentiation GO:0046660 12 0.048
multi organism cellular process GO:0044764 156 0.048
arachidonic acid metabolite production involved in inflammatory response GO:0002538 1 0.048
urogenital system development GO:0001655 65 0.047
embryo development GO:0009790 123 0.047
cellular response to cytokine stimulus GO:0071345 181 0.047
motor neuron axon guidance GO:0008045 2 0.047
response to radiation GO:0009314 151 0.046
actin filament based process GO:0030029 224 0.046
neuron differentiation GO:0030182 138 0.045
neurological system process GO:0050877 163 0.045
negative regulation of oxidative stress induced cell death GO:1903202 17 0.045
Human
positive regulation of intracellular protein transport GO:0090316 76 0.045
positive regulation of lymphocyte activation GO:0051251 73 0.045
positive regulation of fibroblast migration GO:0010763 3 0.044
regulation of cellular response to oxidative stress GO:1900407 26 0.044
Human
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.044
cellular response to nicotine GO:0071316 4 0.044
regulation of growth GO:0040008 165 0.043
guanosine containing compound metabolic process GO:1901068 244 0.043
positive regulation of protein processing GO:0010954 6 0.042
Human
positive regulation of acute inflammatory response GO:0002675 2 0.042
Human
hepatocyte growth factor receptor signaling pathway GO:0048012 8 0.042
Human
endothelial cell migration GO:0043542 86 0.042
purine ribonucleoside metabolic process GO:0046128 437 0.041
granulocyte chemotaxis GO:0071621 37 0.041
regulation of intracellular transport GO:0032386 195 0.041
endodermal cell differentiation GO:0035987 31 0.040
positive regulation of cd8 positive alpha beta t cell activation GO:2001187 1 0.040
single organism carbohydrate metabolic process GO:0044723 193 0.040
regulation of homeostatic process GO:0032844 121 0.040
small molecule biosynthetic process GO:0044283 157 0.039
cellular response to monosaccharide stimulus GO:0071326 10 0.039
Rat
regulation of synaptic transmission GO:0050804 11 0.039
response to mechanical stimulus GO:0009612 51 0.039
response to glucose GO:0009749 19 0.039
Rat
neurotransmitter secretion GO:0007269 4 0.039
epithelium development GO:0060429 227 0.039
Human
multicellular organismal reproductive process GO:0048609 40 0.038
Rat
defense response to gram negative bacterium GO:0050829 14 0.038
lipid biosynthetic process GO:0008610 177 0.037
secretion GO:0046903 254 0.037
negative regulation of protein metabolic process GO:0051248 391 0.037
Human
cellular ion homeostasis GO:0006873 168 0.037
positive regulation of leukocyte proliferation GO:0070665 48 0.037
regulation of fibroblast proliferation GO:0048145 32 0.036
single organism cellular localization GO:1902580 332 0.036
organic hydroxy compound metabolic process GO:1901615 147 0.036
development of primary female sexual characteristics GO:0046545 10 0.036
multi organism reproductive process GO:0044703 54 0.036
Rat
erk1 and erk2 cascade GO:0070371 104 0.036
cellular metal ion homeostasis GO:0006875 146 0.036
peptidyl serine modification GO:0018209 106 0.036
segmentation GO:0035282 4 0.036
regulation of leukocyte cell cell adhesion GO:1903037 7 0.036
hematopoietic or lymphoid organ development GO:0048534 186 0.035
positive regulation of homeostatic process GO:0032846 47 0.035
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.035
ribonucleoside triphosphate catabolic process GO:0009203 391 0.035
nucleotide catabolic process GO:0009166 408 0.035
regulation of response to oxidative stress GO:1902882 26 0.034
Human
reproductive process GO:0022414 106 0.034
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.034
positive regulation of odontogenesis GO:0042482 3 0.034
response to insulin GO:0032868 45 0.034
renal system development GO:0072001 63 0.033
release of cytochrome c from mitochondria GO:0001836 35 0.033
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.033
response to peptide hormone GO:0043434 61 0.033
positive regulation of neuron projection development GO:0010976 34 0.033
positive regulation of nucleoside metabolic process GO:0045979 186 0.033
positive regulation of kinase activity GO:0033674 204 0.033
regulation of nucleotide catabolic process GO:0030811 205 0.033
negative regulation of cell cell adhesion GO:0022408 27 0.032
lipid metabolic process GO:0006629 381 0.032
morphogenesis of a branching structure GO:0001763 21 0.032
Human
cellular chemical homeostasis GO:0055082 180 0.032
Rat
regulation of mapk cascade GO:0043408 262 0.032
phosphatidylinositol mediated signaling GO:0048015 55 0.032
Human
leukocyte cell cell adhesion GO:0007159 37 0.032
cellular ketone metabolic process GO:0042180 80 0.032
nucleoside triphosphate metabolic process GO:0009141 422 0.032
response to light stimulus GO:0009416 87 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.031
cellular response to organic cyclic compound GO:0071407 127 0.031
Rat
positive regulation of axon extension GO:0045773 4 0.031
developmental process involved in reproduction GO:0003006 66 0.031
regulation of gliogenesis GO:0014013 7 0.031
neutrophil chemotaxis GO:0030593 24 0.031
tube morphogenesis GO:0035239 95 0.031

PLAU disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.044
disease of cellular proliferation DOID:14566 174 0.044
sensory system disease DOID:0050155 203 0.036
Human
eye and adnexa disease DOID:1492 150 0.036
nervous system disease DOID:863 431 0.036