Homo sapiens

0 known processes

PLEKHB2

pleckstrin homology domain containing, family B (evectins) member 2

(Aliases: EVT2,FLJ30436,FLJ23679,FLJ20783)

PLEKHB2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.298
inorganic cation transmembrane transport GO:0098662 194 0.200
inorganic ion transmembrane transport GO:0098660 231 0.198
oogenesis GO:0048477 2 0.192
cation transmembrane transport GO:0098655 238 0.185
transmembrane transport GO:0055085 399 0.176
cation transport GO:0006812 331 0.160
ribonucleotide catabolic process GO:0009261 405 0.156
determination of adult lifespan GO:0008340 2 0.148
female gamete generation GO:0007292 2 0.144
vesicle mediated transport GO:0016192 371 0.137
ion transmembrane transport GO:0034220 338 0.136
monovalent inorganic cation transport GO:0015672 128 0.127
purine nucleoside triphosphate metabolic process GO:0009144 412 0.118
cellular sodium ion homeostasis GO:0006883 8 0.117
purine containing compound catabolic process GO:0072523 411 0.108
purine ribonucleoside metabolic process GO:0046128 437 0.108
nucleoside catabolic process GO:0009164 408 0.098
purine ribonucleoside catabolic process GO:0046130 398 0.096
ion homeostasis GO:0050801 230 0.094
cation homeostasis GO:0055080 189 0.093
organophosphate catabolic process GO:0046434 430 0.089
purine nucleotide catabolic process GO:0006195 405 0.088
purine ribonucleotide catabolic process GO:0009154 404 0.086
chemical homeostasis GO:0048878 306 0.085
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.084
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.084
ribonucleoside catabolic process GO:0042454 406 0.083
ribonucleoside triphosphate metabolic process GO:0009199 412 0.083
nucleoside phosphate catabolic process GO:1901292 412 0.082
purine nucleoside catabolic process GO:0006152 398 0.082
cellular cation homeostasis GO:0030003 163 0.078
purine nucleoside triphosphate catabolic process GO:0009146 392 0.075
multicellular organismal aging GO:0010259 3 0.074
cellular ion homeostasis GO:0006873 168 0.072
ribonucleoside triphosphate catabolic process GO:0009203 391 0.071
nucleoside triphosphate metabolic process GO:0009141 422 0.069
cellular chemical homeostasis GO:0055082 180 0.069
cytoplasmic transport GO:0016482 379 0.067
cellular homeostasis GO:0019725 196 0.065
nucleoside triphosphate catabolic process GO:0009143 394 0.063
response to salt stress GO:0009651 3 0.062
cellular metal ion homeostasis GO:0006875 146 0.060
glycosyl compound catabolic process GO:1901658 413 0.058
nucleotide catabolic process GO:0009166 408 0.058
membrane organization GO:0061024 292 0.058
guanosine containing compound metabolic process GO:1901068 244 0.057
ras protein signal transduction GO:0007265 73 0.054
response to abiotic stimulus GO:0009628 336 0.052
cellular divalent inorganic cation homeostasis GO:0072503 128 0.049
secretion by cell GO:0032940 226 0.046
gtp metabolic process GO:0046039 239 0.045
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.044
cell development GO:0048468 328 0.042
monovalent inorganic cation homeostasis GO:0055067 37 0.041
system process GO:0003008 349 0.040
locomotory behavior GO:0007626 1 0.040
single organism membrane organization GO:0044802 268 0.039
anatomical structure formation involved in morphogenesis GO:0048646 284 0.039
gtp catabolic process GO:0006184 237 0.038
dephosphorylation GO:0016311 209 0.038
biological adhesion GO:0022610 331 0.038
regulation of neurotransmitter secretion GO:0046928 3 0.037
endosomal transport GO:0016197 129 0.036
protein localization to organelle GO:0033365 280 0.036
metal ion transport GO:0030001 272 0.036
embryo development GO:0009790 123 0.036
cellular lipid metabolic process GO:0044255 303 0.036
organelle assembly GO:0070925 176 0.035
cellular protein complex assembly GO:0043623 188 0.035
lipid metabolic process GO:0006629 381 0.034
maintenance of location GO:0051235 112 0.033
cellular macromolecule catabolic process GO:0044265 380 0.033
intracellular protein transport GO:0006886 270 0.033
positive regulation of cell death GO:0010942 263 0.033
cell morphogenesis GO:0000902 296 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
guanosine containing compound catabolic process GO:1901069 239 0.032
metal ion homeostasis GO:0055065 169 0.032
cellular component morphogenesis GO:0032989 314 0.031
calcium ion homeostasis GO:0055074 122 0.031
regulation of cellular component biogenesis GO:0044087 281 0.030
amine metabolic process GO:0009308 44 0.030
regulation of purine nucleotide metabolic process GO:1900542 264 0.029
vacuolar transport GO:0007034 34 0.029
cellular amine metabolic process GO:0044106 41 0.028
exocytosis GO:0006887 71 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
anion transport GO:0006820 161 0.027
nucleoside monophosphate metabolic process GO:0009123 191 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.027
cilium assembly GO:0042384 63 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.027
divalent inorganic cation transport GO:0072511 158 0.026
neuromuscular junction development GO:0007528 3 0.026
immune response GO:0006955 307 0.025
small gtpase mediated signal transduction GO:0007264 78 0.025
atp metabolic process GO:0046034 176 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
post golgi vesicle mediated transport GO:0006892 36 0.025
cellular calcium ion homeostasis GO:0006874 117 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
microtubule based process GO:0007017 210 0.025
cell adhesion GO:0007155 325 0.025
cellular protein catabolic process GO:0044257 261 0.024
single organism cellular localization GO:1902580 332 0.024
syncytium formation by plasma membrane fusion GO:0000768 2 0.024
purine nucleoside monophosphate metabolic process GO:0009126 186 0.024
regulation of vesicle mediated transport GO:0060627 130 0.024
epithelium development GO:0060429 227 0.024
endomembrane system organization GO:0010256 196 0.024
segmentation GO:0035282 4 0.024
regulation of cellular response to stress GO:0080135 244 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
cellular response to nutrient levels GO:0031669 69 0.024
cellular amino acid metabolic process GO:0006520 116 0.024
positive regulation of cellular component organization GO:0051130 376 0.024
spermatid development GO:0007286 4 0.023
secretion GO:0046903 254 0.023
atp catabolic process GO:0006200 157 0.023
mitochondrion organization GO:0007005 156 0.023
actin filament based process GO:0030029 224 0.023
regulation of reactive oxygen species metabolic process GO:2000377 41 0.023
divalent inorganic cation homeostasis GO:0072507 136 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
defense response GO:0006952 315 0.022
regulation of ion transport GO:0043269 189 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
regulation of locomotion GO:0040012 329 0.022
lipid localization GO:0010876 106 0.022
endocytosis GO:0006897 159 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.022
ribonucleoside monophosphate metabolic process GO:0009161 187 0.022
axon cargo transport GO:0008088 2 0.021
hydrogen transport GO:0006818 23 0.021
positive regulation of transport GO:0051050 336 0.021
positive regulation of synaptic transmission GO:0050806 4 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
regulation of secretion by cell GO:1903530 177 0.021
protein catabolic process GO:0030163 325 0.021
cell projection organization GO:0030030 252 0.021
growth GO:0040007 202 0.021
cellular response to external stimulus GO:0071496 111 0.021
cell projection assembly GO:0030031 126 0.020
receptor mediated endocytosis GO:0006898 84 0.020
mitotic cell cycle GO:0000278 326 0.020
regulation of cell cycle GO:0051726 393 0.020
regulation of kinase activity GO:0043549 314 0.020
regulation of synaptic plasticity GO:0048167 3 0.020
neurotransmitter secretion GO:0007269 4 0.020
vesicle organization GO:0016050 62 0.020
rna interference GO:0016246 4 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
response to decreased oxygen levels GO:0036293 96 0.020
regulation of transferase activity GO:0051338 355 0.020
response to hypoxia GO:0001666 96 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
oocyte differentiation GO:0009994 2 0.019
cellular component assembly involved in morphogenesis GO:0010927 73 0.019
cilium organization GO:0044782 68 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
nucleoside monophosphate catabolic process GO:0009125 159 0.019
adult locomotory behavior GO:0008344 1 0.018
regulation of cell growth GO:0001558 135 0.018
regulation of protein transport GO:0051223 213 0.018
spermatid differentiation GO:0048515 4 0.018
regulation of cellular amine metabolic process GO:0033238 11 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
cilium morphogenesis GO:0060271 75 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
regulation of transmembrane transport GO:0034762 139 0.018
cell part morphogenesis GO:0032990 137 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
ribonucleoside monophosphate catabolic process GO:0009158 158 0.018
cell cell signaling GO:0007267 155 0.018
calcium ion transmembrane transport GO:0070588 76 0.018
response to oxygen containing compound GO:1901700 369 0.018
vacuole organization GO:0007033 44 0.018
purine nucleoside monophosphate catabolic process GO:0009128 158 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
regulation of secretion GO:0051046 194 0.017
response to external biotic stimulus GO:0043207 261 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
regulation of cell migration GO:0030334 289 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
sodium ion homeostasis GO:0055078 14 0.017
negative regulation of transport GO:0051051 176 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
regulation of growth GO:0040008 165 0.017
regulation of response to external stimulus GO:0032101 222 0.017
regulation of gtpase activity GO:0043087 180 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
divalent metal ion transport GO:0070838 152 0.017
organ morphogenesis GO:0009887 147 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
negative regulation of catabolic process GO:0009895 104 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
cellular monovalent inorganic cation homeostasis GO:0030004 26 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
response to extracellular stimulus GO:0009991 85 0.016
compound eye development GO:0048749 1 0.016
response to oxygen levels GO:0070482 100 0.016
cell growth GO:0016049 160 0.016
nitrogen compound transport GO:0071705 191 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
rho protein signal transduction GO:0007266 26 0.016
negative regulation of cell death GO:0060548 345 0.016
golgi vesicle transport GO:0048193 80 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
regulation of synaptic vesicle transport GO:1902803 3 0.016
vesicle targeting rough er to cis golgi GO:0048207 2 0.016
regulation of immune response GO:0050776 201 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.016
regulation of neuronal synaptic plasticity GO:0048168 1 0.015
blastoderm segmentation GO:0007350 2 0.015
regulation of protein complex assembly GO:0043254 147 0.015
positive regulation of immune system process GO:0002684 283 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
regulation of protein kinase activity GO:0045859 289 0.015
regulation of mapk cascade GO:0043408 262 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
lipid biosynthetic process GO:0008610 177 0.015
negative regulation of cellular catabolic process GO:0031330 83 0.015
anterior posterior axis specification GO:0009948 2 0.015
regeneration GO:0031099 4 0.015
meiotic chromosome segregation GO:0045132 4 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
regulation of protein localization GO:0032880 296 0.015
single organism cell adhesion GO:0098602 179 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
positive regulation of kinase activity GO:0033674 204 0.015
cellular response to starvation GO:0009267 58 0.014
actin cytoskeleton organization GO:0030036 207 0.014
positive regulation of immune response GO:0050778 159 0.014
regulation of cellular component movement GO:0051270 334 0.014
regulation of cell projection organization GO:0031344 107 0.014
calcium ion transport GO:0006816 147 0.014
actin filament organization GO:0007015 128 0.014
cell division GO:0051301 168 0.014
synaptic vesicle exocytosis GO:0016079 3 0.014
apoptotic signaling pathway GO:0097190 268 0.014
associative learning GO:0008306 1 0.014
establishment of vesicle localization GO:0051650 23 0.014
lipid modification GO:0030258 84 0.014
cellular response to extracellular stimulus GO:0031668 72 0.014
regulation of cell cycle process GO:0010564 266 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
regulation of ph GO:0006885 20 0.014
mapk cascade GO:0000165 288 0.014
reproductive process GO:0022414 106 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
cellular ketone metabolic process GO:0042180 80 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
reproduction GO:0000003 63 0.014
synaptic vesicle endocytosis GO:0048488 2 0.013
lipid transport GO:0006869 90 0.013
innate immune response GO:0045087 178 0.013
anterograde axon cargo transport GO:0008089 1 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
proton transport GO:0015992 22 0.013
somitogenesis GO:0001756 2 0.013
protein localization to membrane GO:0072657 160 0.013
organelle localization GO:0051640 84 0.013
glycerolipid metabolic process GO:0046486 107 0.013
organelle fission GO:0048285 149 0.013
neurological system process GO:0050877 163 0.013
cardiac muscle cell apoptotic process GO:0010659 3 0.013
stem cell division GO:0017145 2 0.013
positive regulation of transferase activity GO:0051347 227 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
positive regulation of catabolic process GO:0009896 310 0.013
regulation of cellular ph GO:0030641 17 0.013
wnt signaling pathway GO:0016055 156 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
protein ubiquitination GO:0016567 314 0.013
sequestering of metal ion GO:0051238 24 0.013
nuclear migration GO:0007097 1 0.012
potassium ion transport GO:0006813 62 0.012
immune effector process GO:0002252 159 0.012
protein targeting GO:0006605 187 0.012
negative regulation of cell cycle GO:0045786 193 0.012
oocyte development GO:0048599 1 0.012
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
small molecule biosynthetic process GO:0044283 157 0.012
regulation of intracellular transport GO:0032386 195 0.012
regulation of protein catabolic process GO:0042176 155 0.012
positive regulation of secretion GO:0051047 116 0.012
peptidyl serine modification GO:0018209 106 0.012
cell fate determination GO:0001709 3 0.012
negative regulation of protein modification process GO:0031400 200 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
regulation of metal ion transport GO:0010959 120 0.012
positive regulation of developmental process GO:0051094 314 0.012
regulation of ion transmembrane transport GO:0034765 132 0.012
mitochondrion distribution GO:0048311 3 0.012
regulation of cell motility GO:2000145 299 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
positive regulation of ras gtpase activity GO:0032320 117 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
single organism reproductive process GO:0044702 98 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
apoptotic mitochondrial changes GO:0008637 57 0.012
mitotic cell cycle process GO:1903047 286 0.012
regulation of intracellular ph GO:0051453 16 0.011
negative regulation of organelle organization GO:0010639 126 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
regulation of anatomical structure size GO:0090066 101 0.011
phospholipid metabolic process GO:0006644 99 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
response to fungus GO:0009620 4 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
autophagy GO:0006914 88 0.011
cytokine production GO:0001816 247 0.011
constitutive secretory pathway GO:0045054 3 0.011
synaptic vesicle recycling GO:0036465 3 0.011
visual behavior GO:0007632 2 0.011
melanin metabolic process GO:0006582 1 0.011
response to nutrient levels GO:0031667 81 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of stress activated mapk cascade GO:0032872 84 0.011
interspecies interaction between organisms GO:0044419 156 0.011
myosin filament organization GO:0031033 2 0.011
behavior GO:0007610 112 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
regulation of multi organism process GO:0043900 157 0.011
regulation of membrane potential GO:0042391 95 0.011
regulation of proteolysis GO:0030162 293 0.011
neurogenesis GO:0022008 169 0.011
regulation of transmembrane transporter activity GO:0022898 74 0.011
aging GO:0007568 66 0.011
sulfur compound metabolic process GO:0006790 101 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
hemopoiesis GO:0030097 180 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
memory GO:0007613 3 0.011
peripheral nervous system development GO:0007422 2 0.010
visual learning GO:0008542 1 0.010
response to axon injury GO:0048678 1 0.010
regulation of synaptic vesicle exocytosis GO:2000300 2 0.010
response to hormone GO:0009725 175 0.010
protein dephosphorylation GO:0006470 81 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
positive regulation of locomotion GO:0040017 186 0.010
response to other organism GO:0051707 261 0.010
stress activated mapk cascade GO:0051403 93 0.010
hindbrain development GO:0030902 3 0.010
cdc42 protein signal transduction GO:0032488 4 0.010
cardiovascular system development GO:0072358 262 0.010
viral process GO:0016032 146 0.010
plasma membrane organization GO:0007009 115 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
organic acid catabolic process GO:0016054 71 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
response to lipid GO:0033993 206 0.010
chromosome segregation GO:0007059 114 0.010
intracellular mrna localization GO:0008298 1 0.010
protein secretion GO:0009306 98 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
inner ear morphogenesis GO:0042472 4 0.010
response to biotic stimulus GO:0009607 276 0.010

PLEKHB2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.041
sensory system disease DOID:0050155 203 0.039
nervous system disease DOID:863 431 0.039
immune system disease DOID:2914 155 0.031
eye and adnexa disease DOID:1492 150 0.027
eye disease DOID:5614 149 0.027
central nervous system disease DOID:331 186 0.026
inherited metabolic disorder DOID:655 242 0.023
musculoskeletal system disease DOID:17 223 0.023
lysosomal storage disease DOID:3211 47 0.018
disease of cellular proliferation DOID:14566 174 0.017
connective tissue disease DOID:65 109 0.016
brain disease DOID:936 73 0.015
cancer DOID:162 167 0.015
hematopoietic system disease DOID:74 100 0.015
organ system cancer DOID:0050686 164 0.014
neurodegenerative disease DOID:1289 102 0.013
bone disease DOID:0080001 88 0.013
anemia DOID:2355 55 0.013
retinal disease DOID:5679 118 0.013
retinal degeneration DOID:8466 89 0.010